1850254:LPB137 RS13130
gene id: 1850254:LPB137_RS13130
uniprot id: A0A1P8KQ43
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1850254:LPB137 RS13975
gene id: 1850254:LPB137_RS13975
uniprot id: A0A1P8KQU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1850254:LPB137 RS13940
gene id: 1850254:LPB137_RS13940
uniprot id: A0A1P8KQP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1850254:LPB137 RS02080
gene id: 1850254:LPB137_RS02080
uniprot id: A0A1P8KJN4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1850254:LPB137 RS02700
gene id: 1850254:LPB137_RS02700
uniprot id: A0A1P8KJU7
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1850254:LPB137 RS11360
gene id: 1850254:LPB137_RS11360
uniprot id: A0A1P8KPD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1850254:LPB137 RS04640
gene id: 1850254:LPB137_RS04640
uniprot id: A0A1P8KKW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS02635
gene id: 1850254:LPB137_RS02635
uniprot id: A0A1P8KJU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1850254:LPB137 RS10245
gene id: 1850254:LPB137_RS10245
uniprot id: A0A1P8KR52
names: Similarity
messages: Belongs to the ribF family.

1850254:LPB137 RS12510
gene id: 1850254:LPB137_RS12510
uniprot id: A0A1P8KQ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1850254:LPB137 RS03595
gene id: 1850254:LPB137_RS03595
uniprot id: A0A1P8KKA8
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS02865
gene id: 1850254:LPB137_RS02865
uniprot id: A0A1P8KJY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1850254:LPB137 RS02210
gene id: 1850254:LPB137_RS02210
uniprot id: A0A1P8KJL6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1850254:LPB137 RS06560
gene id: 1850254:LPB137_RS06560
uniprot id: A0A1P8KLV3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1850254:LPB137 RS02045
gene id: 1850254:LPB137_RS02045
uniprot id: A0A1P8KJI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1850254:LPB137 RS13780
gene id: 1850254:LPB137_RS13780
uniprot id: A0A1P8KQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1850254:LPB137 RS01060
gene id: 1850254:LPB137_RS01060
uniprot id: A0A1P8KIZ9
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS08150
gene id: 1850254:LPB137_RS08150
uniprot id: A0A1P8KMS2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS09485
gene id: 1850254:LPB137_RS09485
uniprot id: A0A1P8KNC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1850254:LPB137 RS09910
gene id: 1850254:LPB137_RS09910
uniprot id: A0A1P8KNP0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS04050
gene id: 1850254:LPB137_RS04050
uniprot id: A0A1P8KKI2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1850254:LPB137 RS08035
gene id: 1850254:LPB137_RS08035
uniprot id: A0A1P8KMQ4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS00340
gene id: 1850254:LPB137_RS00340
uniprot id: A0A1P8KIK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1850254:LPB137 RS06050
gene id: 1850254:LPB137_RS06050
uniprot id: A0A1P8KLK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1850254:LPB137 RS13710
gene id: 1850254:LPB137_RS13710
uniprot id: A0A1P8KQL1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS03610
gene id: 1850254:LPB137_RS03610
uniprot id: A0A1P8KK93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1850254:LPB137 RS11855
gene id: 1850254:LPB137_RS11855
uniprot id: A0A1P8KPL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1850254:LPB137 RS13015
gene id: 1850254:LPB137_RS13015
uniprot id: A0A1P8KQ77
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850254:LPB137 RS09495
gene id: 1850254:LPB137_RS09495
uniprot id: A0A1P8KNC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1850254:LPB137 RS10660
gene id: 1850254:LPB137_RS10660
uniprot id: A0A1P8KNU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1850254:LPB137 RS12690
gene id: 1850254:LPB137_RS12690
uniprot id: A0A1P8KPW5
names: Similarity
messages: Belongs to the P(II) protein family.

1850254:LPB137 RS07450
gene id: 1850254:LPB137_RS07450
uniprot id: A0A1P8KMF6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1850254:LPB137 RS12250
gene id: 1850254:LPB137_RS12250
uniprot id: A0A1P8KPU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1850254:LPB137 RS07365
gene id: 1850254:LPB137_RS07365
uniprot id: A0A1P8KMB1
names: Similarity
messages: Belongs to the YggT family.

1850254:LPB137 RS07675
gene id: 1850254:LPB137_RS07675
uniprot id: A0A1P8KMH3
names: Similarity
messages: Belongs to the peptidase A31 family.

1850254:LPB137 RS03685
gene id: 1850254:LPB137_RS03685
uniprot id: A0A1P8KKB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1850254:LPB137 RS07475
gene id: 1850254:LPB137_RS07475
uniprot id: A0A1P8KMA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1850254:LPB137 RS08535
gene id: 1850254:LPB137_RS08535
uniprot id: A0A1P8KR20
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS06270
gene id: 1850254:LPB137_RS06270
uniprot id: A0A1P8KLQ1
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS01120
gene id: 1850254:LPB137_RS01120
uniprot id: A0A1P8KJ10
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1850254:LPB137 RS09235
gene id: 1850254:LPB137_RS09235
uniprot id: A0A1P8KNB7
names: Subcellular Location Annotation
messages: Cytoplasm

1850254:LPB137 RS04880
gene id: 1850254:LPB137_RS04880
uniprot id: A0A1P8KL00
names: Similarity
messages: Belongs to the UPF0251 family.

1850254:LPB137 RS01440
gene id: 1850254:LPB137_RS01440
uniprot id: A0A1P8KJ66
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

1850254:LPB137 RS00365
gene id: 1850254:LPB137_RS00365
uniprot id: A0A1P8KIM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1850254:LPB137 RS05475
gene id: 1850254:LPB137_RS05475
uniprot id: A0A1P8KLA7
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

1850254:LPB137 RS07645
gene id: 1850254:LPB137_RS07645
uniprot id: A0A1P8KMF0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1850254:LPB137 RS03810
gene id: 1850254:LPB137_RS03810
uniprot id: A0A1P8KKE9
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS11145
gene id: 1850254:LPB137_RS11145
uniprot id: A0A1P8KPB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1850254:LPB137 RS04525
gene id: 1850254:LPB137_RS04525
uniprot id: A0A1P8KKS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1850254:LPB137 RS01140
gene id: 1850254:LPB137_RS01140
uniprot id: A0A1P8KJ07
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1850254:LPB137 RS10330
gene id: 1850254:LPB137_RS10330
uniprot id: A0A1P8KNN8
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS00350
gene id: 1850254:LPB137_RS00350
uniprot id: A0A1P8KIL1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1850254:LPB137 RS10685
gene id: 1850254:LPB137_RS10685
uniprot id: A0A1P8KP62
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1850254:LPB137 RS02705
gene id: 1850254:LPB137_RS02705
uniprot id: A0A1P8KQS8
names: Similarity
messages: Belongs to the PqqA family.

1850254:LPB137 RS08030
gene id: 1850254:LPB137_RS08030
uniprot id: A0A1P8KML3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1850254:LPB137 RS02215
gene id: 1850254:LPB137_RS02215
uniprot id: A0A1P8KJK6
names: Similarity
messages: Belongs to the glutamate synthase family.

1850254:LPB137 RS05815
gene id: 1850254:LPB137_RS05815
uniprot id: A0A1P8KLJ3
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1850254:LPB137 RS01610
gene id: 1850254:LPB137_RS01610
uniprot id: A0A1P8KJ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1850254:LPB137 RS09735
gene id: 1850254:LPB137_RS09735
uniprot id: A0A1P8KNK2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1850254:LPB137 RS09610
gene id: 1850254:LPB137_RS09610
uniprot id: A0A1P8KNF2
names: Similarity
messages: Belongs to the UPF0234 family.

1850254:LPB137 RS00165
gene id: 1850254:LPB137_RS00165
uniprot id: A0A1P8KIH8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS10120
gene id: 1850254:LPB137_RS10120
uniprot id: A0A1P8KNR2
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

1850254:LPB137 RS06280
gene id: 1850254:LPB137_RS06280
uniprot id: A0A1P8KLQ9
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS10355
gene id: 1850254:LPB137_RS10355
uniprot id: A0A1P8KNV8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1850254:LPB137 RS02600
gene id: 1850254:LPB137_RS02600
uniprot id: A0A1P8KJS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane

1850254:LPB137 RS11515
gene id: 1850254:LPB137_RS11515
uniprot id: A0A1P8KPG2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Periplasm

1850254:LPB137 RS10345
gene id: 1850254:LPB137_RS10345
uniprot id: A0A1P8KNN7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1850254:LPB137 RS07415
gene id: 1850254:LPB137_RS07415
uniprot id: A0A1P8KMD6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1850254:LPB137 RS04460
gene id: 1850254:LPB137_RS04460
uniprot id: A0A1P8KKS7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1850254:LPB137 RS02155
gene id: 1850254:LPB137_RS02155
uniprot id: A0A1P8KJJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1850254:LPB137 RS11735
gene id: 1850254:LPB137_RS11735
uniprot id: A0A1P8KPE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS07505
gene id: 1850254:LPB137_RS07505
uniprot id: A0A1P8KMD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1850254:LPB137 RS00800
gene id: 1850254:LPB137_RS00800
uniprot id: A0A1P8KIU3
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS09470
gene id: 1850254:LPB137_RS09470
uniprot id: A0A1P8KNJ8
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS11260
gene id: 1850254:LPB137_RS11260
uniprot id: A0A1P8KPA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1850254:LPB137 RS08090
gene id: 1850254:LPB137_RS08090
uniprot id: A0A1P8KMN6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1850254:LPB137 RS12240
gene id: 1850254:LPB137_RS12240
uniprot id: A0A1P8KPV6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1850254:LPB137 RS09965
gene id: 1850254:LPB137_RS09965
uniprot id: A0A1P8KNM7
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS07010
gene id: 1850254:LPB137_RS07010
uniprot id: A0A1P8KM68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1850254:LPB137 RS01205
gene id: 1850254:LPB137_RS01205
uniprot id: A0A1P8KJ39
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1850254:LPB137 RS11370
gene id: 1850254:LPB137_RS11370
uniprot id: A0A1P8KPC7
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1850254:LPB137 RS07960
gene id: 1850254:LPB137_RS07960
uniprot id: A0A1P8KML0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850254:LPB137 RS01905
gene id: 1850254:LPB137_RS01905
uniprot id: A0A1P8KJE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1850254:LPB137 RS06970
gene id: 1850254:LPB137_RS06970
uniprot id: A0A1P8KM24
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1850254:LPB137 RS06780
gene id: 1850254:LPB137_RS06780
uniprot id: A0A1P8KLZ8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1850254:LPB137 RS10740
gene id: 1850254:LPB137_RS10740
uniprot id: A0A1P8KP72
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1850254:LPB137 RS13145
gene id: 1850254:LPB137_RS13145
uniprot id: A0A1P8KQA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1850254:LPB137 RS10650
gene id: 1850254:LPB137_RS10650
uniprot id: A0A1P8KNU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS05650
gene id: 1850254:LPB137_RS05650
uniprot id: A0A1P8KLF1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1850254:LPB137 RS06025
gene id: 1850254:LPB137_RS06025
uniprot id: A0A1P8KLI6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1850254:LPB137 RS04295
gene id: 1850254:LPB137_RS04295
uniprot id: A0A1P8KKQ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1850254:LPB137 RS11560
gene id: 1850254:LPB137_RS11560
uniprot id: A0A1P8KPB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1850254:LPB137 RS10055
gene id: 1850254:LPB137_RS10055
uniprot id: A0A1P8KNQ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1850254:LPB137 RS10260
gene id: 1850254:LPB137_RS10260
uniprot id: A0A1P8KNW5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).

1850254:LPB137 RS02255
gene id: 1850254:LPB137_RS02255
uniprot id: A0A1P8KJL0
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1850254:LPB137 RS04660
gene id: 1850254:LPB137_RS04660
uniprot id: A0A1P8KKW6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850254:LPB137 RS06140
gene id: 1850254:LPB137_RS06140
uniprot id: A0A1P8KQW9
names: Similarity
messages: Belongs to the MlaA family.

1850254:LPB137 RS08070
gene id: 1850254:LPB137_RS08070
uniprot id: A0A1P8KMM1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1850254:LPB137 RS09085
gene id: 1850254:LPB137_RS09085
uniprot id: A0A1P8KNA5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1850254:LPB137 RS11850
gene id: 1850254:LPB137_RS11850
uniprot id: A0A1P8KPS0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1850254:LPB137 RS02455
gene id: 1850254:LPB137_RS02455
uniprot id: A0A1P8KJR0
names: Similarity
messages: Belongs to the Ahb/Nir family.

1850254:LPB137 RS04545
gene id: 1850254:LPB137_RS04545
uniprot id: A0A1P8KKU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1850254:LPB137 RS08210
gene id: 1850254:LPB137_RS08210
uniprot id: A0A1P8KMP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1850254:LPB137 RS11030
gene id: 1850254:LPB137_RS11030
uniprot id: A0A1P8KP99
names: Similarity
messages: Belongs to the UPF0751 family.

1850254:LPB137 RS11245
gene id: 1850254:LPB137_RS11245
uniprot id: A0A1P8KP49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1850254:LPB137 RS02425
gene id: 1850254:LPB137_RS02425
uniprot id: A0A1P8KJP5
names: Similarity
messages: Belongs to the SCO1/2 family.

1850254:LPB137 RS10180
gene id: 1850254:LPB137_RS10180
uniprot id: A0A1P8KNS2
names: Similarity
messages: Belongs to the IMPACT family.

1850254:LPB137 RS13250
gene id: 1850254:LPB137_RS13250
uniprot id: A0A1P8KQB9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS13515
gene id: 1850254:LPB137_RS13515
uniprot id: A0A1P8KQG7
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1850254:LPB137 RS01590
gene id: 1850254:LPB137_RS01590
uniprot id: A0A1P8KJ95
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1850254:LPB137 RS03815
gene id: 1850254:LPB137_RS03815
uniprot id: A0A1P8KKD4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1850254:LPB137 RS11785
gene id: 1850254:LPB137_RS11785
uniprot id: A0A1P8KPR0
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS13350
gene id: 1850254:LPB137_RS13350
uniprot id: A0A1P8KQE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1850254:LPB137 RS01265
gene id: 1850254:LPB137_RS01265
uniprot id: A0A1P8KJ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1850254:LPB137 RS08780
gene id: 1850254:LPB137_RS08780
uniprot id: A0A1P8KMZ8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1850254:LPB137 RS07240
gene id: 1850254:LPB137_RS07240
uniprot id: A0A1P8KQX8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1850254:LPB137 RS10455
gene id: 1850254:LPB137_RS10455
uniprot id: A0A1P8KNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1850254:LPB137 RS07630
gene id: 1850254:LPB137_RS07630
uniprot id: A0A1P8KMD9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1850254:LPB137 RS08745
gene id: 1850254:LPB137_RS08745
uniprot id: A0A1P8KN24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1850254:LPB137 RS01870
gene id: 1850254:LPB137_RS01870
uniprot id: A0A1P8KJJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1850254:LPB137 RS06010
gene id: 1850254:LPB137_RS06010
uniprot id: A0A1P8KLK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1850254:LPB137 RS03135
gene id: 1850254:LPB137_RS03135
uniprot id: A0A1P8KK25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1850254:LPB137 RS07035
gene id: 1850254:LPB137_RS07035
uniprot id: A0A1P8KM31
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1850254:LPB137 RS11630
gene id: 1850254:LPB137_RS11630
uniprot id: A0A1P8KPI4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1850254:LPB137 RS12015
gene id: 1850254:LPB137_RS12015
uniprot id: A0A1P8KPJ0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

1850254:LPB137 RS13965
gene id: 1850254:LPB137_RS13965
uniprot id: A0A1P8KQU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1850254:LPB137 RS10480
gene id: 1850254:LPB137_RS10480
uniprot id: A0A1P8KP11
names: Similarity
messages: Belongs to the fabD family.

1850254:LPB137 RS10635
gene id: 1850254:LPB137_RS10635
uniprot id: A0A1P8KP52
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1850254:LPB137 RS02340
gene id: 1850254:LPB137_RS02340
uniprot id: A0A1P8KJQ3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS01740
gene id: 1850254:LPB137_RS01740
uniprot id: A0A1P8KJB7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1850254:LPB137 RS08900
gene id: 1850254:LPB137_RS08900
uniprot id: A0A1P8KN13
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1850254:LPB137 RS11705
gene id: 1850254:LPB137_RS11705
uniprot id: A0A1P8KPJ3
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1850254:LPB137 RS06565
gene id: 1850254:LPB137_RS06565
uniprot id: A0A1P8KLW0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1850254:LPB137 RS09285
gene id: 1850254:LPB137_RS09285
uniprot id: A0A1P8KNC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1850254:LPB137 RS09425
gene id: 1850254:LPB137_RS09425
uniprot id: A0A1P8KNB1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1850254:LPB137 RS12200
gene id: 1850254:LPB137_RS12200
uniprot id: A0A1P8KPT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS12590
gene id: 1850254:LPB137_RS12590
uniprot id: A0A1P8KQ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS08960
gene id: 1850254:LPB137_RS08960
uniprot id: A0A1P8KN66
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS09795
gene id: 1850254:LPB137_RS09795
uniprot id: A0A1P8KNK0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1850254:LPB137 RS08055
gene id: 1850254:LPB137_RS08055
uniprot id: A0A1P8KMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1850254:LPB137 RS05375
gene id: 1850254:LPB137_RS05375
uniprot id: A0A1P8KLA6
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS07225
gene id: 1850254:LPB137_RS07225
uniprot id: A0A1P8KM67
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS02390
gene id: 1850254:LPB137_RS02390
uniprot id: A0A1P8KJR3
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Periplasm

1850254:LPB137 RS02020
gene id: 1850254:LPB137_RS02020
uniprot id: A0A1P8KJI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1850254:LPB137 RS09515
gene id: 1850254:LPB137_RS09515
uniprot id: A0A1P8KNG6
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1850254:LPB137 RS03850
gene id: 1850254:LPB137_RS03850
uniprot id: A0A1P8KKF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1850254:LPB137 RS03915
gene id: 1850254:LPB137_RS03915
uniprot id: A0A1P8KKG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850254:LPB137 RS01095
gene id: 1850254:LPB137_RS01095
uniprot id: A0A1P8KJ04
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1850254:LPB137 RS12710
gene id: 1850254:LPB137_RS12710
uniprot id: A0A1P8KQ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1850254:LPB137 RS04015
gene id: 1850254:LPB137_RS04015
uniprot id: A0A1P8KKI8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850254:LPB137 RS03455
gene id: 1850254:LPB137_RS03455
uniprot id: A0A1P8KK96
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS03945
gene id: 1850254:LPB137_RS03945
uniprot id: A0A1P8KKG9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1850254:LPB137 RS04800
gene id: 1850254:LPB137_RS04800
uniprot id: A0A1P8KKX4
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1850254:LPB137 RS11905
gene id: 1850254:LPB137_RS11905
uniprot id: A0A1P8KPM7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1850254:LPB137 RS12680
gene id: 1850254:LPB137_RS12680
uniprot id: A0A1P8KQ59
names: Similarity
messages: Belongs to the P(II) protein family.

1850254:LPB137 RS07335
gene id: 1850254:LPB137_RS07335
uniprot id: A0A1P8KM95
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS13765
gene id: 1850254:LPB137_RS13765
uniprot id: A0A1P8KQQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1850254:LPB137 RS00385
gene id: 1850254:LPB137_RS00385
uniprot id: A0A1P8KIM4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1850254:LPB137 RS01630
gene id: 1850254:LPB137_RS01630
uniprot id: A0A1P8KJ98
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1850254:LPB137 RS01110
gene id: 1850254:LPB137_RS01110
uniprot id: A0A1P8KJ06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1850254:LPB137 RS07875
gene id: 1850254:LPB137_RS07875
uniprot id: A0A1P8KMM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1850254:LPB137 RS11700
gene id: 1850254:LPB137_RS11700
uniprot id: A0A1P8KPI8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1850254:LPB137 RS11965
gene id: 1850254:LPB137_RS11965
uniprot id: A0A1P8KPI0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1850254:LPB137 RS01805
gene id: 1850254:LPB137_RS01805
uniprot id: A0A1P8KJC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1850254:LPB137 RS12210
gene id: 1850254:LPB137_RS12210
uniprot id: A0A1P8KPU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1850254:LPB137 RS08490
gene id: 1850254:LPB137_RS08490
uniprot id: A0A1P8KMV1
names: Similarity
messages: Belongs to the peptidase C40 family.

1850254:LPB137 RS03115
gene id: 1850254:LPB137_RS03115
uniprot id: A0A1P8KK40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1850254:LPB137 RS06485
gene id: 1850254:LPB137_RS06485
uniprot id: A0A1P8KLV4
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1850254:LPB137 RS00280
gene id: 1850254:LPB137_RS00280
uniprot id: A0A1P8KIK2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1850254:LPB137 RS11410
gene id: 1850254:LPB137_RS11410
uniprot id: A0A1P8KPE1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1850254:LPB137 RS06460
gene id: 1850254:LPB137_RS06460
uniprot id: A0A1P8KLT7
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS12940
gene id: 1850254:LPB137_RS12940
uniprot id: A0A1P8KQ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS04330
gene id: 1850254:LPB137_RS04330
uniprot id: A0A1P8KQV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1850254:LPB137 RS04210
gene id: 1850254:LPB137_RS04210
uniprot id: A0A1P8KKL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1850254:LPB137 RS10130
gene id: 1850254:LPB137_RS10130
uniprot id: A0A1P8KNQ4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1850254:LPB137 RS06505
gene id: 1850254:LPB137_RS06505
uniprot id: A0A1P8KLU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1850254:LPB137 RS13660
gene id: 1850254:LPB137_RS13660
uniprot id: A0A1P8KQJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1850254:LPB137 RS03305
gene id: 1850254:LPB137_RS03305
uniprot id: A0A1P8KK54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850254:LPB137 RS02270
gene id: 1850254:LPB137_RS02270
uniprot id: A0A1P8KJL8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1850254:LPB137 RS00300
gene id: 1850254:LPB137_RS00300
uniprot id: A0A1P8KIJ8
names: Similarity
messages: Belongs to the asparagine synthetase family.

1850254:LPB137 RS01935
gene id: 1850254:LPB137_RS01935
uniprot id: A0A1P8KJE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1850254:LPB137 RS04480
gene id: 1850254:LPB137_RS04480
uniprot id: A0A1P8KKR4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1850254:LPB137 RS11860
gene id: 1850254:LPB137_RS11860
uniprot id: A0A1P8KPQ4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1850254:LPB137 RS03180
gene id: 1850254:LPB137_RS03180
uniprot id: A0A1P8KK37
names: Subcellular Location Annotation
messages: Nucleus

1850254:LPB137 RS06160
gene id: 1850254:LPB137_RS06160
uniprot id: A0A1P8KLM2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1850254:LPB137 RS06710
gene id: 1850254:LPB137_RS06710
uniprot id: A0A1P8KLW8
names: Similarity
messages: Belongs to the AAA ATPase family.

1850254:LPB137 RS09585
gene id: 1850254:LPB137_RS09585
uniprot id: A0A1P8KNE1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Membrane

1850254:LPB137 RS08145
gene id: 1850254:LPB137_RS08145
uniprot id: A0A1P8KMM3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1850254:LPB137 RS00290
gene id: 1850254:LPB137_RS00290
uniprot id: A0A1P8KIK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1850254:LPB137 RS02790
gene id: 1850254:LPB137_RS02790
uniprot id: A0A1P8KJV6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS08290
gene id: 1850254:LPB137_RS08290
uniprot id: A0A1P8KMV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1850254:LPB137 RS11615
gene id: 1850254:LPB137_RS11615
uniprot id: A0A1P8KPI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1850254:LPB137 RS04680
gene id: 1850254:LPB137_RS04680
uniprot id: A0A1P8KKV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1850254:LPB137 RS12565
gene id: 1850254:LPB137_RS12565
uniprot id: A0A1P8KQ10
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1850254:LPB137 RS08830
gene id: 1850254:LPB137_RS08830
uniprot id: A0A1P8KN51
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1850254:LPB137 RS07005
gene id: 1850254:LPB137_RS07005
uniprot id: A0A1P8KM23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS01930
gene id: 1850254:LPB137_RS01930
uniprot id: A0A1P8KJF9
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1850254:LPB137 RS07160
gene id: 1850254:LPB137_RS07160
uniprot id: A0A1P8KM60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1850254:LPB137 RS05950
gene id: 1850254:LPB137_RS05950
uniprot id: A0A1P8KLL3
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1850254:LPB137 RS06130
gene id: 1850254:LPB137_RS06130
uniprot id: A0A1P8KLP5
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS09525
gene id: 1850254:LPB137_RS09525
uniprot id: A0A1P8KND1
names: Similarity
messages: Belongs to the TrpC family.

1850254:LPB137 RS11070
gene id: 1850254:LPB137_RS11070
uniprot id: A0A1P8KP73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1850254:LPB137 RS09575
gene id: 1850254:LPB137_RS09575
uniprot id: A0A1P8KNE0
names: Similarity
messages: Belongs to the TrpF family.

1850254:LPB137 RS00010
gene id: 1850254:LPB137_RS00010
uniprot id: A0A1P8KIH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

1850254:LPB137 RS06515
gene id: 1850254:LPB137_RS06515
uniprot id: A0A1P8KLU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS04895
gene id: 1850254:LPB137_RS04895
uniprot id: A0A1P8KKZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1850254:LPB137 RS13555
gene id: 1850254:LPB137_RS13555
uniprot id: A0A1P8KQH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1850254:LPB137 RS13690
gene id: 1850254:LPB137_RS13690
uniprot id: A0A1P8KQJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1850254:LPB137 RS00060
gene id: 1850254:LPB137_RS00060
uniprot id: A0A1P8KIG2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1850254:LPB137 RS10405
gene id: 1850254:LPB137_RS10405
uniprot id: A0A1P8KNW7
names: Similarity
messages: Belongs to the thymidylate kinase family.

1850254:LPB137 RS03495
gene id: 1850254:LPB137_RS03495
uniprot id: A0A1P8KK74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1850254:LPB137 RS09075
gene id: 1850254:LPB137_RS09075
uniprot id: A0A1P8KN50
names: Similarity
messages: Belongs to the glutamate synthase family.

1850254:LPB137 RS08600
gene id: 1850254:LPB137_RS08600
uniprot id: A0A1P8KMY3
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS11435
gene id: 1850254:LPB137_RS11435
uniprot id: A0A1P8KPE8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1850254:LPB137 RS01460
gene id: 1850254:LPB137_RS01460
uniprot id: A0A1P8KJ64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1850254:LPB137 RS02580
gene id: 1850254:LPB137_RS02580
uniprot id: A0A1P8KJT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1850254:LPB137 RS03140
gene id: 1850254:LPB137_RS03140
uniprot id: A0A1P8KK29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1850254:LPB137 RS13945
gene id: 1850254:LPB137_RS13945
uniprot id: A0A1P8KQQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1850254:LPB137 RS13715
gene id: 1850254:LPB137_RS13715
uniprot id: A0A1P8KQP1
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS01115
gene id: 1850254:LPB137_RS01115
uniprot id: A0A1P8KJ59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1850254:LPB137 RS06090
gene id: 1850254:LPB137_RS06090
uniprot id: A0A1P8KLN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

1850254:LPB137 RS00710
gene id: 1850254:LPB137_RS00710
uniprot id: A0A1P8KIS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS04475
gene id: 1850254:LPB137_RS04475
uniprot id: A0A1P8KKS0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1850254:LPB137 RS06555
gene id: 1850254:LPB137_RS06555
uniprot id: A0A1P8KLX7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1850254:LPB137 RS03130
gene id: 1850254:LPB137_RS03130
uniprot id: A0A1P8KK27
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1850254:LPB137 RS07305
gene id: 1850254:LPB137_RS07305
uniprot id: A0A1P8KMB6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS13920
gene id: 1850254:LPB137_RS13920
uniprot id: A0A1P8KQQ1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1850254:LPB137 RS10870
gene id: 1850254:LPB137_RS10870
uniprot id: A0A1P8KP71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1850254:LPB137 RS09370
gene id: 1850254:LPB137_RS09370
uniprot id: A0A1P8KNA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1850254:LPB137 RS06955
gene id: 1850254:LPB137_RS06955
uniprot id: A0A1P8KM09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1850254:LPB137 RS02075
gene id: 1850254:LPB137_RS02075
uniprot id: A0A1P8KJJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

1850254:LPB137 RS01475
gene id: 1850254:LPB137_RS01475
uniprot id: A0A1P8KJ63
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS06210
gene id: 1850254:LPB137_RS06210
uniprot id: A0A1P8KLN2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1850254:LPB137 RS00670
gene id: 1850254:LPB137_RS00670
uniprot id: A0A1P8KIS4
names: Similarity
messages: Belongs to the GSP E family.

1850254:LPB137 RS08690
gene id: 1850254:LPB137_RS08690
uniprot id: A0A1P8KN16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1850254:LPB137 RS06350
gene id: 1850254:LPB137_RS06350
uniprot id: A0A1P8KLP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1850254:LPB137 RS11840
gene id: 1850254:LPB137_RS11840
uniprot id: A0A1P8KPL1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1850254:LPB137 RS02375
gene id: 1850254:LPB137_RS02375
uniprot id: A0A1P8KJN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1850254:LPB137 RS08205
gene id: 1850254:LPB137_RS08205
uniprot id: A0A1P8KMV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatB family.
messages: Cell membrane

1850254:LPB137 RS09445
gene id: 1850254:LPB137_RS09445
uniprot id: A0A1P8KNB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

1850254:LPB137 RS06370
gene id: 1850254:LPB137_RS06370
uniprot id: A0A1P8KLQ7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1850254:LPB137 RS00480
gene id: 1850254:LPB137_RS00480
uniprot id: A0A1P8KQV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850254:LPB137 RS11585
gene id: 1850254:LPB137_RS11585
uniprot id: A0A1P8KPN0
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS12340
gene id: 1850254:LPB137_RS12340
uniprot id: A0A1P8KPP1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1850254:LPB137 RS03935
gene id: 1850254:LPB137_RS03935
uniprot id: A0A1P8KKI4
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1850254:LPB137 RS01995
gene id: 1850254:LPB137_RS01995
uniprot id: A0A1P8KJH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS12225
gene id: 1850254:LPB137_RS12225
uniprot id: A0A1P8KPW8
names: Similarity
messages: Belongs to the PrpF family.

1850254:LPB137 RS10865
gene id: 1850254:LPB137_RS10865
uniprot id: A0A1P8KNY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1850254:LPB137 RS06035
gene id: 1850254:LPB137_RS06035
uniprot id: A0A1P8KLM5
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1850254:LPB137 RS06530
gene id: 1850254:LPB137_RS06530
uniprot id: A0A1P8KR00
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1850254:LPB137 RS09880
gene id: 1850254:LPB137_RS09880
uniprot id: A0A1P8KNM3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1850254:LPB137 RS01155
gene id: 1850254:LPB137_RS01155
uniprot id: A0A1P8KJ26
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS08050
gene id: 1850254:LPB137_RS08050
uniprot id: A0A1P8KMQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1850254:LPB137 RS04655
gene id: 1850254:LPB137_RS04655
uniprot id: A0A1P8KKU4
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1850254:LPB137 RS03325
gene id: 1850254:LPB137_RS03325
uniprot id: A0A1P8KKA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850254:LPB137 RS02780
gene id: 1850254:LPB137_RS02780
uniprot id: A0A1P8KK09
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS13010
gene id: 1850254:LPB137_RS13010
uniprot id: A0A1P8KQ84
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS04595
gene id: 1850254:LPB137_RS04595
uniprot id: A0A1P8KKV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1850254:LPB137 RS03875
gene id: 1850254:LPB137_RS03875
uniprot id: A0A1P8KKG7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1850254:LPB137 RS10720
gene id: 1850254:LPB137_RS10720
uniprot id: A0A1P8KP27
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS12180
gene id: 1850254:LPB137_RS12180
uniprot id: A0A1P8KPL3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1850254:LPB137 RS02065
gene id: 1850254:LPB137_RS02065
uniprot id: A0A1P8KJH2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1850254:LPB137 RS10160
gene id: 1850254:LPB137_RS10160
uniprot id: A0A1P8KNS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS04610
gene id: 1850254:LPB137_RS04610
uniprot id: A0A1P8KKV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1850254:LPB137 RS10855
gene id: 1850254:LPB137_RS10855
uniprot id: A0A1P8KP33
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS12535
gene id: 1850254:LPB137_RS12535
uniprot id: A0A1P8KPT6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850254:LPB137 RS03200
gene id: 1850254:LPB137_RS03200
uniprot id: A0A1P8KK46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1850254:LPB137 RS13355
gene id: 1850254:LPB137_RS13355
uniprot id: A0A1P8KQE3
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS04205
gene id: 1850254:LPB137_RS04205
uniprot id: A0A1P8KKL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1850254:LPB137 RS11910
gene id: 1850254:LPB137_RS11910
uniprot id: A0A1P8KPR3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1850254:LPB137 RS08415
gene id: 1850254:LPB137_RS08415
uniprot id: A0A1P8KMS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1850254:LPB137 RS02035
gene id: 1850254:LPB137_RS02035
uniprot id: A0A1P8KJH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1850254:LPB137 RS09885
gene id: 1850254:LPB137_RS09885
uniprot id: A0A1P8KNI1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1850254:LPB137 RS07580
gene id: 1850254:LPB137_RS07580
uniprot id: A0A1P8KMC9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1850254:LPB137 RS02835
gene id: 1850254:LPB137_RS02835
uniprot id: A0A1P8KJZ4
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS02850
gene id: 1850254:LPB137_RS02850
uniprot id: A0A1P8KJW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1850254:LPB137 RS13540
gene id: 1850254:LPB137_RS13540
uniprot id: A0A1P8KQL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1850254:LPB137 RS10670
gene id: 1850254:LPB137_RS10670
uniprot id: A0A1P8KP18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1850254:LPB137 RS00275
gene id: 1850254:LPB137_RS00275
uniprot id: A0A1P8KIJ9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1850254:LPB137 RS11725
gene id: 1850254:LPB137_RS11725
uniprot id: A0A1P8KPD7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1850254:LPB137 RS02725
gene id: 1850254:LPB137_RS02725
uniprot id: A0A1P8KK00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1850254:LPB137 RS07235
gene id: 1850254:LPB137_RS07235
uniprot id: A0A1P8KM90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1850254:LPB137 RS09260
gene id: 1850254:LPB137_RS09260
uniprot id: A0A1P8KNB8
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS03080
gene id: 1850254:LPB137_RS03080
uniprot id: A0A1P8KK17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS08275
gene id: 1850254:LPB137_RS08275
uniprot id: A0A1P8KMV7
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS12575
gene id: 1850254:LPB137_RS12575
uniprot id: A0A1P8KQ19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1850254:LPB137 RS11175
gene id: 1850254:LPB137_RS11175
uniprot id: A0A1P8KP93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1850254:LPB137 RS09170
gene id: 1850254:LPB137_RS09170
uniprot id: A0A1P8KNA4
names: Similarity
messages: Belongs to the DEAD box helicase family.

1850254:LPB137 RS00210
gene id: 1850254:LPB137_RS00210
uniprot id: A0A1P8KIJ2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1850254:LPB137 RS07685
gene id: 1850254:LPB137_RS07685
uniprot id: A0A1P8KMG4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1850254:LPB137 RS01230
gene id: 1850254:LPB137_RS01230
uniprot id: A0A1P8KJ32
names: Similarity
messages: Belongs to the CutA family.

1850254:LPB137 RS12460
gene id: 1850254:LPB137_RS12460
uniprot id: A0A1P8KPY5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1850254:LPB137 RS11340
gene id: 1850254:LPB137_RS11340
uniprot id: A0A1P8KPG3
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1850254:LPB137 RS12270
gene id: 1850254:LPB137_RS12270
uniprot id: A0A1P8KPY0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS00175
gene id: 1850254:LPB137_RS00175
uniprot id: A0A1P8KII5
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS06550
gene id: 1850254:LPB137_RS06550
uniprot id: A0A1P8KLT9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1850254:LPB137 RS01990
gene id: 1850254:LPB137_RS01990
uniprot id: A0A1P8KJG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1850254:LPB137 RS02190
gene id: 1850254:LPB137_RS02190
uniprot id: A0A1P8KJQ5
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS06510
gene id: 1850254:LPB137_RS06510
uniprot id: A0A1P8KLU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1850254:LPB137 RS02810
gene id: 1850254:LPB137_RS02810
uniprot id: A0A1P8KJW7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS01925
gene id: 1850254:LPB137_RS01925
uniprot id: A0A1P8KJK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1850254:LPB137 RS02295
gene id: 1850254:LPB137_RS02295
uniprot id: A0A1P8KJS3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850254:LPB137 RS02310
gene id: 1850254:LPB137_RS02310
uniprot id: A0A1P8KJM5
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS05015
gene id: 1850254:LPB137_RS05015
uniprot id: A0A1P8KL26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1850254:LPB137 RS00715
gene id: 1850254:LPB137_RS00715
uniprot id: A0A1P8KIS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1850254:LPB137 RS08895
gene id: 1850254:LPB137_RS08895
uniprot id: A0A1P8KN74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1850254:LPB137 RS06225
gene id: 1850254:LPB137_RS06225
uniprot id: A0A1P8KLP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS04860
gene id: 1850254:LPB137_RS04860
uniprot id: A0A1P8KL01
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1850254:LPB137 RS01850
gene id: 1850254:LPB137_RS01850
uniprot id: A0A1P8KJD3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1850254:LPB137 RS01225
gene id: 1850254:LPB137_RS01225
uniprot id: A0A1P8KJ28
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS06445
gene id: 1850254:LPB137_RS06445
uniprot id: A0A1P8KLV8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS07620
gene id: 1850254:LPB137_RS07620
uniprot id: A0A1P8KMH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS10605
gene id: 1850254:LPB137_RS10605
uniprot id: A0A1P8KNY7
names: Similarity
messages: Belongs to the RutC family.

1850254:LPB137 RS05205
gene id: 1850254:LPB137_RS05205
uniprot id: A0A1P8KLJ3
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1850254:LPB137 RS01650
gene id: 1850254:LPB137_RS01650
uniprot id: A0A1P8KJD0
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1850254:LPB137 RS11980
gene id: 1850254:LPB137_RS11980
uniprot id: A0A1P8KPP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1850254:LPB137 RS09845
gene id: 1850254:LPB137_RS09845
uniprot id: A0A1P8KNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1850254:LPB137 RS12360
gene id: 1850254:LPB137_RS12360
uniprot id: A0A1P8KPW3
names: Similarity
messages: Belongs to the pyruvate kinase family.

1850254:LPB137 RS07100
gene id: 1850254:LPB137_RS07100
uniprot id: A0A1P8KM55
names: Similarity
messages: Belongs to the ALAD family.

1850254:LPB137 RS03225
gene id: 1850254:LPB137_RS03225
uniprot id: A0A1P8KK88
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850254:LPB137 RS07230
gene id: 1850254:LPB137_RS07230
uniprot id: A0A1P8KMA6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1850254:LPB137 RS09435
gene id: 1850254:LPB137_RS09435
uniprot id: A0A1P8KNB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1850254:LPB137 RS03870
gene id: 1850254:LPB137_RS03870
uniprot id: A0A1P8KKE1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1850254:LPB137 RS04245
gene id: 1850254:LPB137_RS04245
uniprot id: A0A1P8KKP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1850254:LPB137 RS00320
gene id: 1850254:LPB137_RS00320
uniprot id: A0A1P8KIK9
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1850254:LPB137 RS13635
gene id: 1850254:LPB137_RS13635
uniprot id: A0A1P8KR68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1850254:LPB137 RS03510
gene id: 1850254:LPB137_RS03510
uniprot id: A0A1P8KQU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1850254:LPB137 RS12970
gene id: 1850254:LPB137_RS12970
uniprot id: A0A1P8KQ96
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS06600
gene id: 1850254:LPB137_RS06600
uniprot id: A0A1P8KLU9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850254:LPB137 RS07170
gene id: 1850254:LPB137_RS07170
uniprot id: A0A1P8KM82
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS09625
gene id: 1850254:LPB137_RS09625
uniprot id: A0A1P8KNF0
names: Similarity
messages: Belongs to the UPRTase family.

1850254:LPB137 RS13320
gene id: 1850254:LPB137_RS13320
uniprot id: A0A1P8KQF9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1850254:LPB137 RS03065
gene id: 1850254:LPB137_RS03065
uniprot id: A0A1P8KK31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1850254:LPB137 RS12600
gene id: 1850254:LPB137_RS12600
uniprot id: A0A1P8KQ11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1850254:LPB137 RS10335
gene id: 1850254:LPB137_RS10335
uniprot id: A0A1P8KNX4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1850254:LPB137 RS00700
gene id: 1850254:LPB137_RS00700
uniprot id: A0A1P8KIS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1850254:LPB137 RS13235
gene id: 1850254:LPB137_RS13235
uniprot id: A0A1P8KQF6
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS02000
gene id: 1850254:LPB137_RS02000
uniprot id: A0A1P8KJG6
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1850254:LPB137 RS04890
gene id: 1850254:LPB137_RS04890
uniprot id: A0A1P8KL34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1850254:LPB137 RS08215
gene id: 1850254:LPB137_RS08215
uniprot id: A0A1P8KMQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1850254:LPB137 RS07065
gene id: 1850254:LPB137_RS07065
uniprot id: A0A1P8KM56
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1850254:LPB137 RS02650
gene id: 1850254:LPB137_RS02650
uniprot id: A0A1P8KJT8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1850254:LPB137 RS09915
gene id: 1850254:LPB137_RS09915
uniprot id: A0A1P8KNL9
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1850254:LPB137 RS01790
gene id: 1850254:LPB137_RS01790
uniprot id: A0A1P8KQS6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1850254:LPB137 RS00470
gene id: 1850254:LPB137_RS00470
uniprot id: A0A1P8KIP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1850254:LPB137 RS00865
gene id: 1850254:LPB137_RS00865
uniprot id: A0A1P8KIV6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1850254:LPB137 RS13295
gene id: 1850254:LPB137_RS13295
uniprot id: A0A1P8KQH3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1850254:LPB137 RS06235
gene id: 1850254:LPB137_RS06235
uniprot id: A0A1P8KLR7
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1850254:LPB137 RS06545
gene id: 1850254:LPB137_RS06545
uniprot id: A0A1P8KLW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1850254:LPB137 RS03600
gene id: 1850254:LPB137_RS03600
uniprot id: A0A1P8KKA5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1850254:LPB137 RS09065
gene id: 1850254:LPB137_RS09065
uniprot id: A0A1P8KN90
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1850254:LPB137 RS00850
gene id: 1850254:LPB137_RS00850
uniprot id: A0A1P8KIV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1850254:LPB137 RS03295
gene id: 1850254:LPB137_RS03295
uniprot id: A0A1P8KK68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850254:LPB137 RS05970
gene id: 1850254:LPB137_RS05970
uniprot id: A0A1P8KLL8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1850254:LPB137 RS07430
gene id: 1850254:LPB137_RS07430
uniprot id: A0A1P8KMB0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1850254:LPB137 RS04955
gene id: 1850254:LPB137_RS04955
uniprot id: A0A1P8KL16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1850254:LPB137 RS02840
gene id: 1850254:LPB137_RS02840
uniprot id: A0A1P8KK18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1850254:LPB137 RS07745
gene id: 1850254:LPB137_RS07745
uniprot id: A0A1P8KMH0
names: PTM
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1850254:LPB137 RS03100
gene id: 1850254:LPB137_RS03100
uniprot id: A0A1P8KK22
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS10535
gene id: 1850254:LPB137_RS10535
uniprot id: A0A1P8KNS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1850254:LPB137 RS09015
gene id: 1850254:LPB137_RS09015
uniprot id: A0A1P8KNA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1850254:LPB137 RS13880
gene id: 1850254:LPB137_RS13880
uniprot id: A0A1P8KQI0
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1850254:LPB137 RS08920
gene id: 1850254:LPB137_RS08920
uniprot id: A0A1P8KN19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS04240
gene id: 1850254:LPB137_RS04240
uniprot id: A0A1P8KKN4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1850254:LPB137 RS12770
gene id: 1850254:LPB137_RS12770
uniprot id: A0A1P8KQ57
names: Subcellular Location Annotation
messages: Cytoplasm

1850254:LPB137 RS13485
gene id: 1850254:LPB137_RS13485
uniprot id: A0A1P8KQH0
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS00205
gene id: 1850254:LPB137_RS00205
uniprot id: A0A1P8KII6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1850254:LPB137 RS12625
gene id: 1850254:LPB137_RS12625
uniprot id: A0A1P8KQ30
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1850254:LPB137 RS02195
gene id: 1850254:LPB137_RS02195
uniprot id: A0A1P8KJL3
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS00785
gene id: 1850254:LPB137_RS00785
uniprot id: A0A1P8KIV0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1850254:LPB137 RS01045
gene id: 1850254:LPB137_RS01045
uniprot id: A0A1P8KIZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1850254:LPB137 RS05545
gene id: 1850254:LPB137_RS05545
uniprot id: A0A1P8KLE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1850254:LPB137 RS07445
gene id: 1850254:LPB137_RS07445
uniprot id: A0A1P8KMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerH subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1850254:LPB137 RS03240
gene id: 1850254:LPB137_RS03240
uniprot id: A0A1P8KK49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS13435
gene id: 1850254:LPB137_RS13435
uniprot id: A0A1P8KQG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1850254:LPB137 RS05760
gene id: 1850254:LPB137_RS05760
uniprot id: A0A1P8KLI2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1850254:LPB137 RS11995
gene id: 1850254:LPB137_RS11995
uniprot id: A0A1P8KPP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1850254:LPB137 RS03975
gene id: 1850254:LPB137_RS03975
uniprot id: A0A1P8KKG3
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1850254:LPB137 RS12925
gene id: 1850254:LPB137_RS12925
uniprot id: A0A1P8KQA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1850254:LPB137 RS04620
gene id: 1850254:LPB137_RS04620
uniprot id: A0A1P8KKY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1850254:LPB137 RS02550
gene id: 1850254:LPB137_RS02550
uniprot id: A0A1P8KJU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1850254:LPB137 RS10240
gene id: 1850254:LPB137_RS10240
uniprot id: A0A1P8KNS4
names: Similarity
messages: Belongs to the TlyA family.

1850254:LPB137 RS03440
gene id: 1850254:LPB137_RS03440
uniprot id: A0A1P8KK63
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1850254:LPB137 RS10540
gene id: 1850254:LPB137_RS10540
uniprot id: A0A1P8KP06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1850254:LPB137 RS03665
gene id: 1850254:LPB137_RS03665
uniprot id: A0A1P8KKD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1850254:LPB137 RS09250
gene id: 1850254:LPB137_RS09250
uniprot id: A0A1P8KND9
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1850254:LPB137 RS12760
gene id: 1850254:LPB137_RS12760
uniprot id: A0A1P8KQ32
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.

1850254:LPB137 RS00765
gene id: 1850254:LPB137_RS00765
uniprot id: A0A1P8KIT7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1850254:LPB137 RS13990
gene id: 1850254:LPB137_RS13990
uniprot id: A0A1P8KQQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1850254:LPB137 RS07705
gene id: 1850254:LPB137_RS07705
uniprot id: A0A1P8KMK2
names: Similarity
messages: Belongs to the HupF/HypC family.

1850254:LPB137 RS00355
gene id: 1850254:LPB137_RS00355
uniprot id: A0A1P8KIK8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1850254:LPB137 RS01655
gene id: 1850254:LPB137_RS01655
uniprot id: A0A1P8KJB3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1850254:LPB137 RS04580
gene id: 1850254:LPB137_RS04580
uniprot id: A0A1P8KKT5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1850254:LPB137 RS11800
gene id: 1850254:LPB137_RS11800
uniprot id: A0A1P8KPP3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1850254:LPB137 RS08915
gene id: 1850254:LPB137_RS08915
uniprot id: A0A1P8KR36
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1850254:LPB137 RS06820
gene id: 1850254:LPB137_RS06820
uniprot id: A0A1P8KM34
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS12890
gene id: 1850254:LPB137_RS12890
uniprot id: A0A1P8KPZ9
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1850254:LPB137 RS07455
gene id: 1850254:LPB137_RS07455
uniprot id: A0A1P8KMC8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1850254:LPB137 RS03590
gene id: 1850254:LPB137_RS03590
uniprot id: A0A1P8KKA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.

1850254:LPB137 RS11305
gene id: 1850254:LPB137_RS11305
uniprot id: A0A1P8KP57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1850254:LPB137 RS08140
gene id: 1850254:LPB137_RS08140
uniprot id: A0A1P8KMP6
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1850254:LPB137 RS12665
gene id: 1850254:LPB137_RS12665
uniprot id: A0A1P8KQ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1850254:LPB137 RS13600
gene id: 1850254:LPB137_RS13600
uniprot id: A0A1P8KQM6
names: Similarity
messages: Belongs to the RecJ family.

1850254:LPB137 RS07200
gene id: 1850254:LPB137_RS07200
uniprot id: A0A1P8KM72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1850254:LPB137 RS07380
gene id: 1850254:LPB137_RS07380
uniprot id: A0A1P8KMA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1850254:LPB137 RS10690
gene id: 1850254:LPB137_RS10690
uniprot id: A0A1P8KP01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1850254:LPB137 RS12620
gene id: 1850254:LPB137_RS12620
uniprot id: A0A1P8KQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1850254:LPB137 RS00905
gene id: 1850254:LPB137_RS00905
uniprot id: A0A1P8KJ21
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1850254:LPB137 RS11545
gene id: 1850254:LPB137_RS11545
uniprot id: A0A1P8KPK7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1850254:LPB137 RS11440
gene id: 1850254:LPB137_RS11440
uniprot id: A0A1P8KPI7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1850254:LPB137 RS11935
gene id: 1850254:LPB137_RS11935
uniprot id: A0A1P8KPP5
names: Similarity
messages: Belongs to the UbiD family.

1850254:LPB137 RS04805
gene id: 1850254:LPB137_RS04805
uniprot id: A0A1P8KKY7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1850254:LPB137 RS05310
gene id: 1850254:LPB137_RS05310
uniprot id: A0A1P8KL73
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

1850254:LPB137 RS12955
gene id: 1850254:LPB137_RS12955
uniprot id: A0A1P8KQ73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1850254:LPB137 RS04415
gene id: 1850254:LPB137_RS04415
uniprot id: A0A1P8KKU3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS13255
gene id: 1850254:LPB137_RS13255
uniprot id: A0A1P8KQC3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS05055
gene id: 1850254:LPB137_RS05055
uniprot id: A0A1P8KL28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS10485
gene id: 1850254:LPB137_RS10485
uniprot id: A0A1P8KNR7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1850254:LPB137 RS02140
gene id: 1850254:LPB137_RS02140
uniprot id: A0A1P8KJJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS11445
gene id: 1850254:LPB137_RS11445
uniprot id: A0A1P8KP87
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1850254:LPB137 RS11280
gene id: 1850254:LPB137_RS11280
uniprot id: A0A1P8KPH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1850254:LPB137 RS10340
gene id: 1850254:LPB137_RS10340
uniprot id: A0A1P8KR15
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1850254:LPB137 RS03490
gene id: 1850254:LPB137_RS03490
uniprot id: A0A1P8KK89
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1850254:LPB137 RS10500
gene id: 1850254:LPB137_RS10500
uniprot id: A0A1P8KNW9
names: Subcellular Location Annotation
messages: Periplasm

1850254:LPB137 RS12990
gene id: 1850254:LPB137_RS12990
uniprot id: A0A1P8KQ24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1850254:LPB137 RS07260
gene id: 1850254:LPB137_RS07260
uniprot id: A0A1P8KM85
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS01660
gene id: 1850254:LPB137_RS01660
uniprot id: A0A1P8KJF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1850254:LPB137 RS11555
gene id: 1850254:LPB137_RS11555
uniprot id: A0A1P8KPJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1850254:LPB137 RS12010
gene id: 1850254:LPB137_RS12010
uniprot id: A0A1P8KPT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1850254:LPB137 RS00015
gene id: 1850254:LPB137_RS00015
uniprot id: A0A1P8KIF3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1850254:LPB137 RS10730
gene id: 1850254:LPB137_RS10730
uniprot id: A0A1P8KP15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS02315
gene id: 1850254:LPB137_RS02315
uniprot id: A0A1P8KJN7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850254:LPB137 RS02540
gene id: 1850254:LPB137_RS02540
uniprot id: A0A1P8KJR1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1850254:LPB137 RS08085
gene id: 1850254:LPB137_RS08085
uniprot id: A0A1P8KMR3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1850254:LPB137 RS07810
gene id: 1850254:LPB137_RS07810
uniprot id: A0A1P8KMI1
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1850254:LPB137 RS05725
gene id: 1850254:LPB137_RS05725
uniprot id: A0A1P8KLF8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1850254:LPB137 RS10815
gene id: 1850254:LPB137_RS10815
uniprot id: A0A1P8KNX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1850254:LPB137 RS04530
gene id: 1850254:LPB137_RS04530
uniprot id: A0A1P8KKS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1850254:LPB137 RS02030
gene id: 1850254:LPB137_RS02030
uniprot id: A0A1P8KJH6
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS07935
gene id: 1850254:LPB137_RS07935
uniprot id: A0A1P8KML1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1850254:LPB137 RS06995
gene id: 1850254:LPB137_RS06995
uniprot id: A0A1P8KM36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1850254:LPB137 RS10555
gene id: 1850254:LPB137_RS10555
uniprot id: A0A1P8KNZ6
names: Similarity
messages: Belongs to the ParB family.

1850254:LPB137 RS04600
gene id: 1850254:LPB137_RS04600
uniprot id: A0A1P8KKU0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1850254:LPB137 RS11055
gene id: 1850254:LPB137_RS11055
uniprot id: A0A1P8KP74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1850254:LPB137 RS12615
gene id: 1850254:LPB137_RS12615
uniprot id: A0A1P8KQ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1850254:LPB137 RS11080
gene id: 1850254:LPB137_RS11080
uniprot id: A0A1P8KR49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1850254:LPB137 RS03940
gene id: 1850254:LPB137_RS03940
uniprot id: A0A1P8KKK6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1850254:LPB137 RS10580
gene id: 1850254:LPB137_RS10580
uniprot id: A0A1P8KNX9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1850254:LPB137 RS12975
gene id: 1850254:LPB137_RS12975
uniprot id: A0A1P8KQB6
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS11950
gene id: 1850254:LPB137_RS11950
uniprot id: A0A1P8KPT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1850254:LPB137 RS03020
gene id: 1850254:LPB137_RS03020
uniprot id: A0A1P8KK48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1850254:LPB137 RS10530
gene id: 1850254:LPB137_RS10530
uniprot id: A0A1P8KP21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1850254:LPB137 RS11425
gene id: 1850254:LPB137_RS11425
uniprot id: A0A1P8KPE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1850254:LPB137 RS04740
gene id: 1850254:LPB137_RS04740
uniprot id: A0A1P8KKW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1850254:LPB137 RS10830
gene id: 1850254:LPB137_RS10830
uniprot id: A0A1P8KP29
names: Similarity
messages: Belongs to the GSP E family.

1850254:LPB137 RS02060
gene id: 1850254:LPB137_RS02060
uniprot id: A0A1P8KQU3
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1850254:LPB137 RS09440
gene id: 1850254:LPB137_RS09440
uniprot id: A0A1P8KNF6
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS12005
gene id: 1850254:LPB137_RS12005
uniprot id: A0A1P8KPP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1850254:LPB137 RS09500
gene id: 1850254:LPB137_RS09500
uniprot id: A0A1P8KNG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1850254:LPB137 RS12540
gene id: 1850254:LPB137_RS12540
uniprot id: A0A1P8KQ35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1850254:LPB137 RS09805
gene id: 1850254:LPB137_RS09805
uniprot id: A0A1P8KNH5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1850254:LPB137 RS07615
gene id: 1850254:LPB137_RS07615
uniprot id: A0A1P8KMD5
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS09640
gene id: 1850254:LPB137_RS09640
uniprot id: A0A1P8KNL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1850254:LPB137 RS07295
gene id: 1850254:LPB137_RS07295
uniprot id: A0A1P8KM99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1850254:LPB137 RS03340
gene id: 1850254:LPB137_RS03340
uniprot id: A0A1P8KK71
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS04905
gene id: 1850254:LPB137_RS04905
uniprot id: A0A1P8KL07
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1850254:LPB137 RS07805
gene id: 1850254:LPB137_RS07805
uniprot id: A0A1P8KMI0
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1850254:LPB137 RS12215
gene id: 1850254:LPB137_RS12215
uniprot id: A0A1P8KPX1
names: Similarity
messages: Belongs to the citrate synthase family.

1850254:LPB137 RS09835
gene id: 1850254:LPB137_RS09835
uniprot id: A0A1P8KNP9
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

1850254:LPB137 RS00720
gene id: 1850254:LPB137_RS00720
uniprot id: A0A1P8KIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1850254:LPB137 RS08100
gene id: 1850254:LPB137_RS08100
uniprot id: A0A1P8KMR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS02750
gene id: 1850254:LPB137_RS02750
uniprot id: A0A1P8KJX3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1850254:LPB137 RS10350
gene id: 1850254:LPB137_RS10350
uniprot id: A0A1P8KNU2
names: Similarity
messages: Belongs to the GPI family.

1850254:LPB137 RS12300
gene id: 1850254:LPB137_RS12300
uniprot id: A0A1P8KPV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1850254:LPB137 RS03855
gene id: 1850254:LPB137_RS03855
uniprot id: A0A1P8KKF7
names: Cofactor
names: Function
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Binds 1 zinc ion per subunit.

1850254:LPB137 RS04215
gene id: 1850254:LPB137_RS04215
uniprot id: A0A1P8KKM3
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS12655
gene id: 1850254:LPB137_RS12655
uniprot id: A0A1P8KQ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1850254:LPB137 RS07345
gene id: 1850254:LPB137_RS07345
uniprot id: A0A1P8KMA9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS00030
gene id: 1850254:LPB137_RS00030
uniprot id: A0A1P8KQR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1850254:LPB137 RS11625
gene id: 1850254:LPB137_RS11625
uniprot id: A0A1P8KPH6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1850254:LPB137 RS13400
gene id: 1850254:LPB137_RS13400
uniprot id: A0A1P8KQE9
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1850254:LPB137 RS04455
gene id: 1850254:LPB137_RS04455
uniprot id: A0A1P8KQY7
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1850254:LPB137 RS01980
gene id: 1850254:LPB137_RS01980
uniprot id: A0A1P8KJH0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1850254:LPB137 RS03825
gene id: 1850254:LPB137_RS03825
uniprot id: A0A1P8KKF6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS10325
gene id: 1850254:LPB137_RS10325
uniprot id: A0A1P8KNT5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850254:LPB137 RS03715
gene id: 1850254:LPB137_RS03715
uniprot id: A0A1P8KKE0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1850254:LPB137 RS03255
gene id: 1850254:LPB137_RS03255
uniprot id: A0A1P8KK44
names: Similarity
messages: Belongs to the peptidase M24B family.

1850254:LPB137 RS08270
gene id: 1850254:LPB137_RS08270
uniprot id: A0A1P8KMR0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1850254:LPB137 RS01940
gene id: 1850254:LPB137_RS01940
uniprot id: A0A1P8KJG1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1850254:LPB137 RS05335
gene id: 1850254:LPB137_RS05335
uniprot id: A0A1P8KL70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1850254:LPB137 RS01600
gene id: 1850254:LPB137_RS01600
uniprot id: A0A1P8KJ97
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1850254:LPB137 RS12915
gene id: 1850254:LPB137_RS12915
uniprot id: A0A1P8KQ88
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1850254:LPB137 RS07070
gene id: 1850254:LPB137_RS07070
uniprot id: A0A1P8KM43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1850254:LPB137 RS04550
gene id: 1850254:LPB137_RS04550
uniprot id: A0A1P8KKT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1850254:LPB137 RS09620
gene id: 1850254:LPB137_RS09620
uniprot id: A0A1P8KNM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1850254:LPB137 RS13850
gene id: 1850254:LPB137_RS13850
uniprot id: A0A1P8KQR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1850254:LPB137 RS08910
gene id: 1850254:LPB137_RS08910
uniprot id: A0A1P8KN79
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1850254:LPB137 RS10595
gene id: 1850254:LPB137_RS10595
uniprot id: A0A1P8KP19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1850254:LPB137 RS04045
gene id: 1850254:LPB137_RS04045
uniprot id: A0A1P8KKI7
names: Similarity
messages: Belongs to the SufE family.

1850254:LPB137 RS01880
gene id: 1850254:LPB137_RS01880
uniprot id: A0A1P8KJE6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1850254:LPB137 RS01310
gene id: 1850254:LPB137_RS01310
uniprot id: A0A1P8KJ36
names: Similarity
messages: Belongs to the GSP E family.

1850254:LPB137 RS08685
gene id: 1850254:LPB137_RS08685
uniprot id: A0A1P8KMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1850254:LPB137 RS09890
gene id: 1850254:LPB137_RS09890
uniprot id: A0A1P8KNR1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1850254:LPB137 RS12285
gene id: 1850254:LPB137_RS12285
uniprot id: A0A1P8KPN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1850254:LPB137 RS13360
gene id: 1850254:LPB137_RS13360
uniprot id: A0A1P8KQD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1850254:LPB137 RS11990
gene id: 1850254:LPB137_RS11990
uniprot id: A0A1P8KPP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1850254:LPB137 RS07860
gene id: 1850254:LPB137_RS07860
uniprot id: A0A1P8KMI8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850254:LPB137 RS01975
gene id: 1850254:LPB137_RS01975
uniprot id: A0A1P8KJL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1850254:LPB137 RS11960
gene id: 1850254:LPB137_RS11960
uniprot id: A0A1P8KPS3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1850254:LPB137 RS10460
gene id: 1850254:LPB137_RS10460
uniprot id: A0A1P8KNV5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1850254:LPB137 RS09785
gene id: 1850254:LPB137_RS09785
uniprot id: A0A1P8KNN4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1850254:LPB137 RS05200
gene id: 1850254:LPB137_RS05200
uniprot id: A0A1P8KLG3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1850254:LPB137 RS03880
gene id: 1850254:LPB137_RS03880
uniprot id: A0A1P8KKH4
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS10050
gene id: 1850254:LPB137_RS10050
uniprot id: A0A1P8KNK6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS11605
gene id: 1850254:LPB137_RS11605
uniprot id: A0A1P8KPK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1850254:LPB137 RS04395
gene id: 1850254:LPB137_RS04395
uniprot id: A0A1P8KKQ3
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1850254:LPB137 RS06880
gene id: 1850254:LPB137_RS06880
uniprot id: A0A1P8KM22
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1850254:LPB137 RS10200
gene id: 1850254:LPB137_RS10200
uniprot id: A0A1P8KNL8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850254:LPB137 RS09990
gene id: 1850254:LPB137_RS09990
uniprot id: A0A1P8KNJ5
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS06260
gene id: 1850254:LPB137_RS06260
uniprot id: A0A1P8KLP1
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS00390
gene id: 1850254:LPB137_RS00390
uniprot id: A0A1P8KIM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850254:LPB137 RS13335
gene id: 1850254:LPB137_RS13335
uniprot id: A0A1P8KQH5
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS10875
gene id: 1850254:LPB137_RS10875
uniprot id: A0A1P8KNY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1850254:LPB137 RS04065
gene id: 1850254:LPB137_RS04065
uniprot id: A0A1P8KKK0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1850254:LPB137 RS07495
gene id: 1850254:LPB137_RS07495
uniprot id: A0A1P8KMC5
names: Similarity
messages: Belongs to the GARS family.

1850254:LPB137 RS09970
gene id: 1850254:LPB137_RS09970
uniprot id: A0A1P8KNP1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1850254:LPB137 RS09050
gene id: 1850254:LPB137_RS09050
uniprot id: A0A1P8KN43
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS01105
gene id: 1850254:LPB137_RS01105
uniprot id: A0A1P8KJ16
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1850254:LPB137 RS13085
gene id: 1850254:LPB137_RS13085
uniprot id: A0A1P8KQC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1850254:LPB137 RS12755
gene id: 1850254:LPB137_RS12755
uniprot id: A0A1P8KQ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1850254:LPB137 RS04265
gene id: 1850254:LPB137_RS04265
uniprot id: A0A1P8KKN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1850254:LPB137 RS12780
gene id: 1850254:LPB137_RS12780
uniprot id: A0A1P8KQ55
names: Caution
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterohexamer of 3 UreA (alpha) and 3 UreB (beta) subunits.
messages: The orthologous protein is known as the alpha subunit (UreC) in most other bacteria.

1850254:LPB137 RS01895
gene id: 1850254:LPB137_RS01895
uniprot id: A0A1P8KJF8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1850254:LPB137 RS10370
gene id: 1850254:LPB137_RS10370
uniprot id: A0A1P8KP03
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1850254:LPB137 RS03580
gene id: 1850254:LPB137_RS03580
uniprot id: A0A1P8KK95
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1850254:LPB137 RS06540
gene id: 1850254:LPB137_RS06540
uniprot id: A0A1P8KLW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1850254:LPB137 RS04195
gene id: 1850254:LPB137_RS04195
uniprot id: A0A1P8KKQ1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1850254:LPB137 RS04300
gene id: 1850254:LPB137_RS04300
uniprot id: A0A1P8KKR8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1850254:LPB137 RS11345
gene id: 1850254:LPB137_RS11345
uniprot id: A0A1P8KP68
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

1850254:LPB137 RS08815
gene id: 1850254:LPB137_RS08815
uniprot id: A0A1P8KMZ9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1850254:LPB137 RS10525
gene id: 1850254:LPB137_RS10525
uniprot id: A0A1P8KNX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1850254:LPB137 RS09905
gene id: 1850254:LPB137_RS09905
uniprot id: A0A1P8KNM6
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1850254:LPB137 RS04585
gene id: 1850254:LPB137_RS04585
uniprot id: A0A1P8KKT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1850254:LPB137 RS00190
gene id: 1850254:LPB137_RS00190
uniprot id: A0A1P8KII0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1850254:LPB137 RS02405
gene id: 1850254:LPB137_RS02405
uniprot id: A0A1P8KJQ1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Secreted

1850254:LPB137 RS13395
gene id: 1850254:LPB137_RS13395
uniprot id: A0A1P8KQJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1850254:LPB137 RS04835
gene id: 1850254:LPB137_RS04835
uniprot id: A0A1P8KL03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS13775
gene id: 1850254:LPB137_RS13775
uniprot id: A0A1P8KQQ7
names: Similarity
messages: Belongs to the TPP enzyme family.

1850254:LPB137 RS02770
gene id: 1850254:LPB137_RS02770
uniprot id: A0A1P8KJY1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1850254:LPB137 RS05330
gene id: 1850254:LPB137_RS05330
uniprot id: A0A1P8KL94
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS11955
gene id: 1850254:LPB137_RS11955
uniprot id: A0A1P8KPN6
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

1850254:LPB137 RS04005
gene id: 1850254:LPB137_RS04005
uniprot id: A0A1P8KKI1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850254:LPB137 RS10315
gene id: 1850254:LPB137_RS10315
uniprot id: A0A1P8KNZ2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850254:LPB137 RS11750
gene id: 1850254:LPB137_RS11750
uniprot id: A0A1P8KPK0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1850254:LPB137 RS12410
gene id: 1850254:LPB137_RS12410
uniprot id: A0A1P8KPY2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1850254:LPB137 RS10585
gene id: 1850254:LPB137_RS10585
uniprot id: A0A1P8KP30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1850254:LPB137 RS11040
gene id: 1850254:LPB137_RS11040
uniprot id: A0A1P8KP64
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1850254:LPB137 RS13345
gene id: 1850254:LPB137_RS13345
uniprot id: A0A1P8KQH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1850254:LPB137 RS12630
gene id: 1850254:LPB137_RS12630
uniprot id: A0A1P8KQ47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.

1850254:LPB137 RS05690
gene id: 1850254:LPB137_RS05690
uniprot id: A0A1P8KLC9
names: Similarity
messages: Belongs to the peptidase C40 family.

1850254:LPB137 RS00225
gene id: 1850254:LPB137_RS00225
uniprot id: A0A1P8KIJ3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1850254:LPB137 RS09770
gene id: 1850254:LPB137_RS09770
uniprot id: A0A1P8KNH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS04605
gene id: 1850254:LPB137_RS04605
uniprot id: A0A1P8KKT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1850254:LPB137 RS03905
gene id: 1850254:LPB137_RS03905
uniprot id: A0A1P8KKG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1850254:LPB137 RS00840
gene id: 1850254:LPB137_RS00840
uniprot id: A0A1P8KIV2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1850254:LPB137 RS04185
gene id: 1850254:LPB137_RS04185
uniprot id: A0A1P8KKM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850254:LPB137 RS13125
gene id: 1850254:LPB137_RS13125
uniprot id: A0A1P8KQD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1850254:LPB137 RS12695
gene id: 1850254:LPB137_RS12695
uniprot id: A0A1P8KQ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS08710
gene id: 1850254:LPB137_RS08710
uniprot id: A0A1P8KMY8
names: Similarity
messages: Belongs to the ArsC family.

1850254:LPB137 RS08195
gene id: 1850254:LPB137_RS08195
uniprot id: A0A1P8KMN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1850254:LPB137 RS01145
gene id: 1850254:LPB137_RS01145
uniprot id: A0A1P8KJ18
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1850254:LPB137 RS00820
gene id: 1850254:LPB137_RS00820
uniprot id: A0A1P8KIV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1850254:LPB137 RS03710
gene id: 1850254:LPB137_RS03710
uniprot id: A0A1P8KKB2
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS12560
gene id: 1850254:LPB137_RS12560
uniprot id: A0A1P8KQ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1850254:LPB137 RS03565
gene id: 1850254:LPB137_RS03565
uniprot id: A0A1P8KKB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS09360
gene id: 1850254:LPB137_RS09360
uniprot id: A0A1P8KND7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1850254:LPB137 RS00475
gene id: 1850254:LPB137_RS00475
uniprot id: A0A1P8KIN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1850254:LPB137 RS07255
gene id: 1850254:LPB137_RS07255
uniprot id: A0A1P8KPW3
names: Similarity
messages: Belongs to the pyruvate kinase family.

1850254:LPB137 RS02010
gene id: 1850254:LPB137_RS02010
uniprot id: A0A1P8KJG4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1850254:LPB137 RS11330
gene id: 1850254:LPB137_RS11330
uniprot id: A0A1P8KPI1
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1850254:LPB137 RS10925
gene id: 1850254:LPB137_RS10925
uniprot id: A0A1P8KP80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1850254:LPB137 RS00900
gene id: 1850254:LPB137_RS00900
uniprot id: A0A1P8KIW4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850254:LPB137 RS11645
gene id: 1850254:LPB137_RS11645
uniprot id: A0A1P8KPI5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1850254:LPB137 RS07125
gene id: 1850254:LPB137_RS07125
uniprot id: A0A1P8KM51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1850254:LPB137 RS13860
gene id: 1850254:LPB137_RS13860
uniprot id: A0A1P8KR33
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1850254:LPB137 RS07700
gene id: 1850254:LPB137_RS07700
uniprot id: A0A1P8KMG2
names: Similarity
messages: Belongs to the HypD family.

1850254:LPB137 RS12640
gene id: 1850254:LPB137_RS12640
uniprot id: A0A1P8KQ53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1850254:LPB137 RS01645
gene id: 1850254:LPB137_RS01645
uniprot id: A0A1P8KJA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1850254:LPB137 RS12130
gene id: 1850254:LPB137_RS12130
uniprot id: A0A1P8KPK5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1850254:LPB137 RS07055
gene id: 1850254:LPB137_RS07055
uniprot id: A0A1P8KM37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1850254:LPB137 RS12815
gene id: 1850254:LPB137_RS12815
uniprot id: A0A1P8KQ70
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS09475
gene id: 1850254:LPB137_RS09475
uniprot id: A0A1P8KNC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1850254:LPB137 RS00230
gene id: 1850254:LPB137_RS00230
uniprot id: A0A1P8KIJ0
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS01695
gene id: 1850254:LPB137_RS01695
uniprot id: A0A1P8KJB4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1850254:LPB137 RS08870
gene id: 1850254:LPB137_RS08870
uniprot id: A0A1P8KN28
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1850254:LPB137 RS13370
gene id: 1850254:LPB137_RS13370
uniprot id: A0A1P8KQG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1850254:LPB137 RS04410
gene id: 1850254:LPB137_RS04410
uniprot id: A0A1P8KKS3
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1850254:LPB137 RS08835
gene id: 1850254:LPB137_RS08835
uniprot id: A0A1P8KN09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1850254:LPB137 RS13725
gene id: 1850254:LPB137_RS13725
uniprot id: A0A1P8KQP7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS01430
gene id: 1850254:LPB137_RS01430
uniprot id: A0A1P8KJ61
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1850254:LPB137 RS02445
gene id: 1850254:LPB137_RS02445
uniprot id: A0A1P8KJS4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1850254:LPB137 RS03920
gene id: 1850254:LPB137_RS03920
uniprot id: A0A1P8KKF5
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

1850254:LPB137 RS12195
gene id: 1850254:LPB137_RS12195
uniprot id: A0A1P8KPT8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1850254:LPB137 RS01615
gene id: 1850254:LPB137_RS01615
uniprot id: A0A1P8KJA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1850254:LPB137 RS04290
gene id: 1850254:LPB137_RS04290
uniprot id: A0A1P8KKP4
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS11970
gene id: 1850254:LPB137_RS11970
uniprot id: A0A1P8KPR8
names: Similarity
messages: Belongs to the citrate synthase family.

1850254:LPB137 RS00115
gene id: 1850254:LPB137_RS00115
uniprot id: A0A1P8KII9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1850254:LPB137 RS09090
gene id: 1850254:LPB137_RS09090
uniprot id: A0A1P8KN45
names: Similarity
messages: Belongs to the hemerythrin family.

1850254:LPB137 RS03260
gene id: 1850254:LPB137_RS03260
uniprot id: A0A1P8KK41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1850254:LPB137 RS01605
gene id: 1850254:LPB137_RS01605
uniprot id: A0A1P8KJE1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1850254:LPB137 RS07945
gene id: 1850254:LPB137_RS07945
uniprot id: A0A1P8KMN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1850254:LPB137 RS12580
gene id: 1850254:LPB137_RS12580
uniprot id: A0A1P8KQ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1850254:LPB137 RS13405
gene id: 1850254:LPB137_RS13405
uniprot id: A0A1P8KQF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1850254:LPB137 RS07185
gene id: 1850254:LPB137_RS07185
uniprot id: A0A1P8KM80
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1850254:LPB137 RS07425
gene id: 1850254:LPB137_RS07425
uniprot id: A0A1P8KM98
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1850254:LPB137 RS11985
gene id: 1850254:LPB137_RS11985
uniprot id: A0A1P8KPQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1850254:LPB137 RS11650
gene id: 1850254:LPB137_RS11650
uniprot id: A0A1P8KPM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1850254:LPB137 RS13865
gene id: 1850254:LPB137_RS13865
uniprot id: A0A1P8KQS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1850254:LPB137 RS00755
gene id: 1850254:LPB137_RS00755
uniprot id: A0A1P8KIZ1
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS03230
gene id: 1850254:LPB137_RS03230
uniprot id: A0A1P8KK47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1850254:LPB137 RS13700
gene id: 1850254:LPB137_RS13700
uniprot id: A0A1P8KQN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1850254:LPB137 RS08245
gene id: 1850254:LPB137_RS08245
uniprot id: A0A1P8KMP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1850254:LPB137 RS11415
gene id: 1850254:LPB137_RS11415
uniprot id: A0A1P8KPF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cytoplasm

1850254:LPB137 RS12350
gene id: 1850254:LPB137_RS12350
uniprot id: A0A1P8KPX4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1850254:LPB137 RS07060
gene id: 1850254:LPB137_RS07060
uniprot id: A0A1P8KM79
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1850254:LPB137 RS11740
gene id: 1850254:LPB137_RS11740
uniprot id: A0A1P8KPK4
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS01745
gene id: 1850254:LPB137_RS01745
uniprot id: A0A1P8KJC0
names: Similarity
messages: Belongs to the thioredoxin family.

1850254:LPB137 RS11085
gene id: 1850254:LPB137_RS11085
uniprot id: A0A1P8KP20
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1850254:LPB137 RS01965
gene id: 1850254:LPB137_RS01965
uniprot id: A0A1P8KJJ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1850254:LPB137 RS01765
gene id: 1850254:LPB137_RS01765
uniprot id: A0A1P8KJH4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1850254:LPB137 RS05820
gene id: 1850254:LPB137_RS05820
uniprot id: A0A1P8KLG3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1850254:LPB137 RS11310
gene id: 1850254:LPB137_RS11310
uniprot id: A0A1P8KPB6
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

1850254:LPB137 RS05235
gene id: 1850254:LPB137_RS05235
uniprot id: A0A1P8KL52
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1850254:LPB137 RS07785
gene id: 1850254:LPB137_RS07785
uniprot id: A0A1P8KMI5
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1850254:LPB137 RS08785
gene id: 1850254:LPB137_RS08785
uniprot id: A0A1P8KN36
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850254:LPB137 RS04165
gene id: 1850254:LPB137_RS04165
uniprot id: A0A1P8KKL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1850254:LPB137 RS12605
gene id: 1850254:LPB137_RS12605
uniprot id: A0A1P8KQ16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.

1850254:LPB137 RS01080
gene id: 1850254:LPB137_RS01080
uniprot id: A0A1P8KJ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1850254:LPB137 RS13330
gene id: 1850254:LPB137_RS13330
uniprot id: A0A1P8KQE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1850254:LPB137 RS13670
gene id: 1850254:LPB137_RS13670
uniprot id: A0A1P8KQK6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1850254:LPB137 RS01550
gene id: 1850254:LPB137_RS01550
uniprot id: A0A1P8KJ82
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS13520
gene id: 1850254:LPB137_RS13520
uniprot id: A0A1P8KQJ4
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1850254:LPB137 RS00360
gene id: 1850254:LPB137_RS00360
uniprot id: A0A1P8KIL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1850254:LPB137 RS09130
gene id: 1850254:LPB137_RS09130
uniprot id: A0A1P8KN98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS04540
gene id: 1850254:LPB137_RS04540
uniprot id: A0A1P8KKT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1850254:LPB137 RS00775
gene id: 1850254:LPB137_RS00775
uniprot id: A0A1P8KIU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1850254:LPB137 RS11265
gene id: 1850254:LPB137_RS11265
uniprot id: A0A1P8KPC5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1850254:LPB137 RS06480
gene id: 1850254:LPB137_RS06480
uniprot id: A0A1P8KLS2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS12445
gene id: 1850254:LPB137_RS12445
uniprot id: A0A1P8KPR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1850254:LPB137 RS11730
gene id: 1850254:LPB137_RS11730
uniprot id: A0A1P8KPM9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS08630
gene id: 1850254:LPB137_RS08630
uniprot id: A0A1P8KN29
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS10810
gene id: 1850254:LPB137_RS10810
uniprot id: A0A1P8KR27
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS06850
gene id: 1850254:LPB137_RS06850
uniprot id: A0A1P8KLZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1850254:LPB137 RS04845
gene id: 1850254:LPB137_RS04845
uniprot id: A0A1P8KKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS06950
gene id: 1850254:LPB137_RS06950
uniprot id: A0A1P8KM13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1850254:LPB137 RS10365
gene id: 1850254:LPB137_RS10365
uniprot id: A0A1P8KNV0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1850254:LPB137 RS07550
gene id: 1850254:LPB137_RS07550
uniprot id: A0A1P8KMH6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1850254:LPB137 RS01825
gene id: 1850254:LPB137_RS01825
uniprot id: A0A1P8KJD6
names: Cofactor
names: Similarity
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.

1850254:LPB137 RS04575
gene id: 1850254:LPB137_RS04575
uniprot id: A0A1P8KKT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1850254:LPB137 RS02240
gene id: 1850254:LPB137_RS02240
uniprot id: A0A1P8KJR4
names: Similarity
messages: Belongs to the arginase family.

1850254:LPB137 RS11620
gene id: 1850254:LPB137_RS11620
uniprot id: A0A1P8KPJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1850254:LPB137 RS01005
gene id: 1850254:LPB137_RS01005
uniprot id: A0A1P8KJ40
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS01150
gene id: 1850254:LPB137_RS01150
uniprot id: A0A1P8KJ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1850254:LPB137 RS04090
gene id: 1850254:LPB137_RS04090
uniprot id: A0A1P8KKL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

1850254:LPB137 RS06770
gene id: 1850254:LPB137_RS06770
uniprot id: A0A1P8KLY9
names: Similarity
messages: Belongs to the YjdM family.

1850254:LPB137 RS07530
gene id: 1850254:LPB137_RS07530
uniprot id: A0A1P8KMD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1850254:LPB137 RS06455
gene id: 1850254:LPB137_RS06455
uniprot id: A0A1P8KLT3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1850254:LPB137 RS11675
gene id: 1850254:LPB137_RS11675
uniprot id: A0A1P8KPC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1850254:LPB137 RS01635
gene id: 1850254:LPB137_RS01635
uniprot id: A0A1P8KJ99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS03550
gene id: 1850254:LPB137_RS03550
uniprot id: A0A1P8KK84
names: Similarity
messages: Belongs to the MEMO1 family.

1850254:LPB137 RS06535
gene id: 1850254:LPB137_RS06535
uniprot id: A0A1P8KLT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1850254:LPB137 RS01185
gene id: 1850254:LPB137_RS01185
uniprot id: A0A1P8KJ19
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS07610
gene id: 1850254:LPB137_RS07610
uniprot id: A0A1P8KMF8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1850254:LPB137 RS06295
gene id: 1850254:LPB137_RS06295
uniprot id: A0A1P8KQQ9
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS01795
gene id: 1850254:LPB137_RS01795
uniprot id: A0A1P8KJC1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1850254:LPB137 RS05560
gene id: 1850254:LPB137_RS05560
uniprot id: A0A1P8KLC8
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1850254:LPB137 RS10630
gene id: 1850254:LPB137_RS10630
uniprot id: A0A1P8KNZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1850254:LPB137 RS01340
gene id: 1850254:LPB137_RS01340
uniprot id: A0A1P8KJ60
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1850254:LPB137 RS03060
gene id: 1850254:LPB137_RS03060
uniprot id: A0A1P8KQX7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1850254:LPB137 RS08000
gene id: 1850254:LPB137_RS08000
uniprot id: A0A1P8KMP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1850254:LPB137 RS12550
gene id: 1850254:LPB137_RS12550
uniprot id: A0A1P8KQ02
names: Similarity
messages: Belongs to the ArsC family.

1850254:LPB137 RS04535
gene id: 1850254:LPB137_RS04535
uniprot id: A0A1P8KKT1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1850254:LPB137 RS07245
gene id: 1850254:LPB137_RS07245
uniprot id: A0A1P8KM66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1850254:LPB137 RS11680
gene id: 1850254:LPB137_RS11680
uniprot id: A0A1P8KPL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS04280
gene id: 1850254:LPB137_RS04280
uniprot id: A0A1P8KKN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS06650
gene id: 1850254:LPB137_RS06650
uniprot id: A0A1P8KLV9
names: Subunit
messages: Homodimer.

1850254:LPB137 RS11365
gene id: 1850254:LPB137_RS11365
uniprot id: A0A1P8KPE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1850254:LPB137 RS03830
gene id: 1850254:LPB137_RS03830
uniprot id: A0A1P8KKG4
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS00055
gene id: 1850254:LPB137_RS00055
uniprot id: A0A1P8KIF8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1850254:LPB137 RS00160
gene id: 1850254:LPB137_RS00160
uniprot id: A0A1P8KIH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS10665
gene id: 1850254:LPB137_RS10665
uniprot id: A0A1P8KNZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1850254:LPB137 RS08625
gene id: 1850254:LPB137_RS08625
uniprot id: A0A1P8KN10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1850254:LPB137 RS12355
gene id: 1850254:LPB137_RS12355
uniprot id: A0A1P8KPX0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850254:LPB137 RS02435
gene id: 1850254:LPB137_RS02435
uniprot id: A0A1P8KJP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS06860
gene id: 1850254:LPB137_RS06860
uniprot id: A0A1P8KM21
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1850254:LPB137 RS01575
gene id: 1850254:LPB137_RS01575
uniprot id: A0A1P8KJ89
names: Similarity
messages: Belongs to the peptidase S41A family.

1850254:LPB137 RS12725
gene id: 1850254:LPB137_RS12725
uniprot id: A0A1P8KQ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1850254:LPB137 RS12810
gene id: 1850254:LPB137_RS12810
uniprot id: A0A1P8KQ42
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS04870
gene id: 1850254:LPB137_RS04870
uniprot id: A0A1P8KKY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1850254:LPB137 RS04135
gene id: 1850254:LPB137_RS04135
uniprot id: A0A1P8KKL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1850254:LPB137 RS09815
gene id: 1850254:LPB137_RS09815
uniprot id: A0A1P8KNQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1850254:LPB137 RS09955
gene id: 1850254:LPB137_RS09955
uniprot id: A0A1P8KNN6
names: Similarity
messages: Belongs to the glutamate synthase family.

1850254:LPB137 RS01395
gene id: 1850254:LPB137_RS01395
uniprot id: A0A1P8KJ71
names: Similarity
messages: Belongs to the CFA/CMAS family.

1850254:LPB137 RS04060
gene id: 1850254:LPB137_RS04060
uniprot id: A0A1P8KKJ5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1850254:LPB137 RS06475
gene id: 1850254:LPB137_RS06475
uniprot id: A0A1P8KLS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1850254:LPB137 RS04260
gene id: 1850254:LPB137_RS04260
uniprot id: A0A1P8KKM1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1850254:LPB137 RS04130
gene id: 1850254:LPB137_RS04130
uniprot id: A0A1P8KKJ3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1850254:LPB137 RS12295
gene id: 1850254:LPB137_RS12295
uniprot id: A0A1P8KPW6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1850254:LPB137 RS10625
gene id: 1850254:LPB137_RS10625
uniprot id: A0A1P8KNY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1850254:LPB137 RS01040
gene id: 1850254:LPB137_RS01040
uniprot id: A0A1P8KIY4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1850254:LPB137 RS00410
gene id: 1850254:LPB137_RS00410
uniprot id: A0A1P8KIM1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850254:LPB137 RS06875
gene id: 1850254:LPB137_RS06875
uniprot id: A0A1P8KM44
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1850254:LPB137 RS09920
gene id: 1850254:LPB137_RS09920
uniprot id: A0A1P8KNN3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1850254:LPB137 RS02695
gene id: 1850254:LPB137_RS02695
uniprot id: A0A1P8KJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS10590
gene id: 1850254:LPB137_RS10590
uniprot id: A0A1P8KNT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1850254:LPB137 RS04570
gene id: 1850254:LPB137_RS04570
uniprot id: A0A1P8KKX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1850254:LPB137 RS07420
gene id: 1850254:LPB137_RS07420
uniprot id: A0A1P8KMC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1850254:LPB137 RS03245
gene id: 1850254:LPB137_RS03245
uniprot id: A0A1P8KK60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS06250
gene id: 1850254:LPB137_RS06250
uniprot id: A0A1P8KLR4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS06680
gene id: 1850254:LPB137_RS06680
uniprot id: A0A1P8KQX9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS11225
gene id: 1850254:LPB137_RS11225
uniprot id: A0A1P8KPA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1850254:LPB137 RS04515
gene id: 1850254:LPB137_RS04515
uniprot id: A0A1P8KKU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1850254:LPB137 RS12515
gene id: 1850254:LPB137_RS12515
uniprot id: A0A1P8KPZ6
names: Subcellular Location Annotation
messages: Cytoplasm

1850254:LPB137 RS13930
gene id: 1850254:LPB137_RS13930
uniprot id: A0A1P8KQI9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1850254:LPB137 RS05975
gene id: 1850254:LPB137_RS05975
uniprot id: A0A1P8KLJ1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1850254:LPB137 RS05785
gene id: 1850254:LPB137_RS05785
uniprot id: A0A1P8KLG1
names: Similarity
messages: Belongs to the RutC family.

1850254:LPB137 RS05075
gene id: 1850254:LPB137_RS05075
uniprot id: A0A1P8KL43
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1850254:LPB137 RS12420
gene id: 1850254:LPB137_RS12420
uniprot id: A0A1P8KQ25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1850254:LPB137 RS12400
gene id: 1850254:LPB137_RS12400
uniprot id: A0A1P8KPY3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1850254:LPB137 RS04820
gene id: 1850254:LPB137_RS04820
uniprot id: A0A1P8KKX5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1850254:LPB137 RS04555
gene id: 1850254:LPB137_RS04555
uniprot id: A0A1P8KKS4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1850254:LPB137 RS00005
gene id: 1850254:LPB137_RS00005
uniprot id: A0A1P8KIF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1850254:LPB137 RS05100
gene id: 1850254:LPB137_RS05100
uniprot id: A0A1P8KL72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1850254:LPB137 RS12670
gene id: 1850254:LPB137_RS12670
uniprot id: A0A1P8KQ65
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1850254:LPB137 RS13375
gene id: 1850254:LPB137_RS13375
uniprot id: A0A1P8KQI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1850254:LPB137 RS14270
gene id: 1850254:LPB137_RS14270
uniprot id: A0A1P8KQN1
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1850254:LPB137 RS12170
gene id: 1850254:LPB137_RS12170
uniprot id: A0A1P8KPL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1850254:LPB137 RS05980
gene id: 1850254:LPB137_RS05980
uniprot id: A0A1P8KLM7
names: Similarity
messages: Belongs to the thioredoxin family.

1850254:LPB137 RS03765
gene id: 1850254:LPB137_RS03765
uniprot id: A0A1P8KKC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1850254:LPB137 RS02125
gene id: 1850254:LPB137_RS02125
uniprot id: A0A1P8KJL1
names: Similarity
messages: Belongs to the proline racemase family.

1850254:LPB137 RS10375
gene id: 1850254:LPB137_RS10375
uniprot id: A0A1P8KNU4
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS08865
gene id: 1850254:LPB137_RS08865
uniprot id: A0A1P8KN05
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1850254:LPB137 RS07925
gene id: 1850254:LPB137_RS07925
uniprot id: A0A1P8KMJ8
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS01955
gene id: 1850254:LPB137_RS01955
uniprot id: A0A1P8KJF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850254:LPB137 RS01810
gene id: 1850254:LPB137_RS01810
uniprot id: A0A1P8KJF6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1850254:LPB137 RS10520
gene id: 1850254:LPB137_RS10520
uniprot id: A0A1P8KP32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1850254:LPB137 RS01720
gene id: 1850254:LPB137_RS01720
uniprot id: A0A1P8KJA9
names: Similarity
messages: Belongs to the peptidase C40 family.

1850254:LPB137 RS02355
gene id: 1850254:LPB137_RS02355
uniprot id: A0A1P8KJN0
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS03705
gene id: 1850254:LPB137_RS03705
uniprot id: A0A1P8KKB4
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS12885
gene id: 1850254:LPB137_RS12885
uniprot id: A0A1P8KQ91
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS08860
gene id: 1850254:LPB137_RS08860
uniprot id: A0A1P8KN69
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

1850254:LPB137 RS03275
gene id: 1850254:LPB137_RS03275
uniprot id: A0A1P8KK97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1850254:LPB137 RS02775
gene id: 1850254:LPB137_RS02775
uniprot id: A0A1P8KJY3
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS02610
gene id: 1850254:LPB137_RS02610
uniprot id: A0A1P8KJV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1850254:LPB137 RS05395
gene id: 1850254:LPB137_RS05395
uniprot id: A0A1P8KL96
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1850254:LPB137 RS13950
gene id: 1850254:LPB137_RS13950
uniprot id: A0A1P8KQP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1850254:LPB137 RS11465
gene id: 1850254:LPB137_RS11465
uniprot id: A0A1P8KPG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1850254:LPB137 RS07905
gene id: 1850254:LPB137_RS07905
uniprot id: A0A1P8KMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1850254:LPB137 RS12450
gene id: 1850254:LPB137_RS12450
uniprot id: A0A1P8KPZ3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1850254:LPB137 RS04320
gene id: 1850254:LPB137_RS04320
uniprot id: A0A1P8KKP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1850254:LPB137 RS11500
gene id: 1850254:LPB137_RS11500
uniprot id: A0A1P8KPA1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1850254:LPB137 RS04445
gene id: 1850254:LPB137_RS04445
uniprot id: A0A1P8KKR0
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1850254:LPB137 RS02760
gene id: 1850254:LPB137_RS02760
uniprot id: A0A1P8KJV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS12105
gene id: 1850254:LPB137_RS12105
uniprot id: A0A1P8KPR7
names: Similarity
messages: Belongs to the RutC family.

1850254:LPB137 RS01800
gene id: 1850254:LPB137_RS01800
uniprot id: A0A1P8KJC7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1850254:LPB137 RS02250
gene id: 1850254:LPB137_RS02250
uniprot id: A0A1P8KJM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1850254:LPB137 RS08515
gene id: 1850254:LPB137_RS08515
uniprot id: A0A1P8KMU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1850254:LPB137 RS08230
gene id: 1850254:LPB137_RS08230
uniprot id: A0A1P8KMP7
names: Subcellular Location Annotation
messages: Cytoplasm

1850254:LPB137 RS05910
gene id: 1850254:LPB137_RS05910
uniprot id: A0A1P8KLG8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1850254:LPB137 RS11140
gene id: 1850254:LPB137_RS11140
uniprot id: A0A1P8KP28
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1850254:LPB137 RS03520
gene id: 1850254:LPB137_RS03520
uniprot id: A0A1P8KKC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1850254:LPB137 RS12025
gene id: 1850254:LPB137_RS12025
uniprot id: A0A1P8KPI6
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1850254:LPB137 RS02845
gene id: 1850254:LPB137_RS02845
uniprot id: A0A1P8KJX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1850254:LPB137 RS01075
gene id: 1850254:LPB137_RS01075
uniprot id: A0A1P8KIZ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1850254:LPB137 RS04465
gene id: 1850254:LPB137_RS04465
uniprot id: A0A1P8KKT2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1850254:LPB137 RS04615
gene id: 1850254:LPB137_RS04615
uniprot id: A0A1P8KKW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1850254:LPB137 RS06965
gene id: 1850254:LPB137_RS06965
uniprot id: A0A1P8KM45
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1850254:LPB137 RS13705
gene id: 1850254:LPB137_RS13705
uniprot id: A0A1P8KQP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1850254:LPB137 RS09385
gene id: 1850254:LPB137_RS09385
uniprot id: A0A1P8KNE6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1850254:LPB137 RS12305
gene id: 1850254:LPB137_RS12305
uniprot id: A0A1P8KPV3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1850254:LPB137 RS12390
gene id: 1850254:LPB137_RS12390
uniprot id: A0A1P8KPZ8
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS11095
gene id: 1850254:LPB137_RS11095
uniprot id: A0A1P8KP16
names: Function
names: Similarity
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.

1850254:LPB137 RS01985
gene id: 1850254:LPB137_RS01985
uniprot id: A0A1P8KJG0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1850254:LPB137 RS01690
gene id: 1850254:LPB137_RS01690
uniprot id: A0A1P8KJB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1850254:LPB137 RS04520
gene id: 1850254:LPB137_RS04520
uniprot id: A0A1P8KKW0
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

1850254:LPB137 RS13665
gene id: 1850254:LPB137_RS13665
uniprot id: A0A1P8KQY3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1850254:LPB137 RS01775
gene id: 1850254:LPB137_RS01775
uniprot id: A0A1P8KJC5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS00745
gene id: 1850254:LPB137_RS00745
uniprot id: A0A1P8KIV1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850254:LPB137 RS04115
gene id: 1850254:LPB137_RS04115
uniprot id: A0A1P8KKK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1850254:LPB137 RS10600
gene id: 1850254:LPB137_RS10600
uniprot id: A0A1P8KNT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1850254:LPB137 RS11635
gene id: 1850254:LPB137_RS11635
uniprot id: A0A1P8KPP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1850254:LPB137 RS07490
gene id: 1850254:LPB137_RS07490
uniprot id: A0A1P8KMC2
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS07500
gene id: 1850254:LPB137_RS07500
uniprot id: A0A1P8KMG6
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1850254:LPB137 RS11685
gene id: 1850254:LPB137_RS11685
uniprot id: A0A1P8KPD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1850254:LPB137 RS02805
gene id: 1850254:LPB137_RS02805
uniprot id: A0A1P8KJX6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1850254:LPB137 RS06835
gene id: 1850254:LPB137_RS06835
uniprot id: A0A1P8KM08
names: Similarity
messages: Belongs to the nitroreductase family.

1850254:LPB137 RS04100
gene id: 1850254:LPB137_RS04100
uniprot id: A0A1P8KKJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS12555
gene id: 1850254:LPB137_RS12555
uniprot id: A0A1P8KQ03
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1850254:LPB137 RS06625
gene id: 1850254:LPB137_RS06625
uniprot id: A0A1P8KLY5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1850254:LPB137 RS01915
gene id: 1850254:LPB137_RS01915
uniprot id: A0A1P8KJI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1850254:LPB137 RS01100
gene id: 1850254:LPB137_RS01100
uniprot id: A0A1P8KJ03
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1850254:LPB137 RS07525
gene id: 1850254:LPB137_RS07525
uniprot id: A0A1P8KMB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1850254:LPB137 RS10570
gene id: 1850254:LPB137_RS10570
uniprot id: A0A1P8KNY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS01950
gene id: 1850254:LPB137_RS01950
uniprot id: A0A1P8KJF7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1850254:LPB137 RS04565
gene id: 1850254:LPB137_RS04565
uniprot id: A0A1P8KKV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1850254:LPB137 RS02710
gene id: 1850254:LPB137_RS02710
uniprot id: A0A1P8KJU1
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1850254:LPB137 RS07370
gene id: 1850254:LPB137_RS07370
uniprot id: A0A1P8KM88
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1850254:LPB137 RS13195
gene id: 1850254:LPB137_RS13195
uniprot id: A0A1P8KQF0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1850254:LPB137 RS07710
gene id: 1850254:LPB137_RS07710
uniprot id: A0A1P8KMH7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1850254:LPB137 RS07735
gene id: 1850254:LPB137_RS07735
uniprot id: A0A1P8KMH5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1850254:LPB137 RS13535
gene id: 1850254:LPB137_RS13535
uniprot id: A0A1P8KQI6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1850254:LPB137 RS04915
gene id: 1850254:LPB137_RS04915
uniprot id: A0A1P8KL11
names: Similarity
messages: Belongs to the arginase family.

1850254:LPB137 RS13365
gene id: 1850254:LPB137_RS13365
uniprot id: A0A1P8KQG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1850254:LPB137 RS06300
gene id: 1850254:LPB137_RS06300
uniprot id: A0A1P8KLN9
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS01640
gene id: 1850254:LPB137_RS01640
uniprot id: A0A1P8KJA4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1850254:LPB137 RS13530
gene id: 1850254:LPB137_RS13530
uniprot id: A0A1P8KQL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1850254:LPB137 RS10550
gene id: 1850254:LPB137_RS10550
uniprot id: A0A1P8KNX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1850254:LPB137 RS08805
gene id: 1850254:LPB137_RS08805
uniprot id: A0A1P8KN34
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1850254:LPB137 RS11610
gene id: 1850254:LPB137_RS11610
uniprot id: A0A1P8KPC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1850254:LPB137 RS07410
gene id: 1850254:LPB137_RS07410
uniprot id: A0A1P8KM96
names: Similarity
messages: Belongs to the aspartokinase family.

1850254:LPB137 RS01180
gene id: 1850254:LPB137_RS01180
uniprot id: A0A1P8KJ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1850254:LPB137 RS11335
gene id: 1850254:LPB137_RS11335
uniprot id: A0A1P8KPC4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1850254:LPB137 RS06915
gene id: 1850254:LPB137_RS06915
uniprot id: A0A1P8KM35
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS02055
gene id: 1850254:LPB137_RS02055
uniprot id: A0A1P8KJH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1850254:LPB137 RS03660
gene id: 1850254:LPB137_RS03660
uniprot id: A0A1P8KKA3
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS05390
gene id: 1850254:LPB137_RS05390
uniprot id: A0A1P8KL79
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS07560
gene id: 1850254:LPB137_RS07560
uniprot id: A0A1P8KMC4
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS01470
gene id: 1850254:LPB137_RS01470
uniprot id: A0A1P8KJ77
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1850254:LPB137 RS04980
gene id: 1850254:LPB137_RS04980
uniprot id: A0A1P8KL05
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1850254:LPB137 RS00285
gene id: 1850254:LPB137_RS00285
uniprot id: A0A1P8KIK0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1850254:LPB137 RS00440
gene id: 1850254:LPB137_RS00440
uniprot id: A0A1P8KIN5
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS03055
gene id: 1850254:LPB137_RS03055
uniprot id: A0A1P8KK01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1850254:LPB137 RS08925
gene id: 1850254:LPB137_RS08925
uniprot id: A0A1P8KN39
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1850254:LPB137 RS03015
gene id: 1850254:LPB137_RS03015
uniprot id: A0A1P8KK24
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1850254:LPB137 RS04695
gene id: 1850254:LPB137_RS04695
uniprot id: A0A1P8KQU8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1850254:LPB137 RS10060
gene id: 1850254:LPB137_RS10060
uniprot id: A0A1P8KNR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS05295
gene id: 1850254:LPB137_RS05295
uniprot id: A0A1P8KLA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1850254:LPB137 RS13090
gene id: 1850254:LPB137_RS13090
uniprot id: A0A1P8KQ41
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1850254:LPB137 RS04170
gene id: 1850254:LPB137_RS04170
uniprot id: A0A1P8KKL9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1850254:LPB137 RS10800
gene id: 1850254:LPB137_RS10800
uniprot id: A0A1P8KP67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1850254:LPB137 RS02325
gene id: 1850254:LPB137_RS02325
uniprot id: A0A1P8KJM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS13230
gene id: 1850254:LPB137_RS13230
uniprot id: A0A1P8KQC7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS08525
gene id: 1850254:LPB137_RS08525
uniprot id: A0A1P8KN14
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1850254:LPB137 RS10545
gene id: 1850254:LPB137_RS10545
uniprot id: A0A1P8KNS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1850254:LPB137 RS06695
gene id: 1850254:LPB137_RS06695
uniprot id: A0A1P8KLW1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS09655
gene id: 1850254:LPB137_RS09655
uniprot id: A0A1P8KNJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS01750
gene id: 1850254:LPB137_RS01750
uniprot id: A0A1P8KJC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1850254:LPB137 RS00180
gene id: 1850254:LPB137_RS00180
uniprot id: A0A1P8KII2
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

1850254:LPB137 RS09290
gene id: 1850254:LPB137_RS09290
uniprot id: A0A1P8KN86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1850254:LPB137 RS10035
gene id: 1850254:LPB137_RS10035
uniprot id: A0A1P8KNQ1
names: Similarity
messages: Belongs to the hemerythrin family.

1850254:LPB137 RS04085
gene id: 1850254:LPB137_RS04085
uniprot id: A0A1P8KQY0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1850254:LPB137 RS11075
gene id: 1850254:LPB137_RS11075
uniprot id: A0A1P8KPB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1850254:LPB137 RS10675
gene id: 1850254:LPB137_RS10675
uniprot id: A0A1P8KNZ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1850254:LPB137 RS08840
gene id: 1850254:LPB137_RS08840
uniprot id: A0A1P8KN46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1850254:LPB137 RS07320
gene id: 1850254:LPB137_RS07320
uniprot id: A0A1P8KM94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1850254:LPB137 RS03070
gene id: 1850254:LPB137_RS03070
uniprot id: A0A1P8KK36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1850254:LPB137 RS12435
gene id: 1850254:LPB137_RS12435
uniprot id: A0A1P8KPR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1850254:LPB137 RS10320
gene id: 1850254:LPB137_RS10320
uniprot id: A0A1P8KNT4
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS05660
gene id: 1850254:LPB137_RS05660
uniprot id: A0A1P8KLD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1850254:LPB137 RS02040
gene id: 1850254:LPB137_RS02040
uniprot id: A0A1P8KJI3
names: Similarity
messages: Belongs to the threonine synthase family.

1850254:LPB137 RS09740
gene id: 1850254:LPB137_RS09740
uniprot id: A0A1P8KNH0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1850254:LPB137 RS04425
gene id: 1850254:LPB137_RS04425
uniprot id: A0A1P8KKQ5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1850254:LPB137 RS11150
gene id: 1850254:LPB137_RS11150
uniprot id: A0A1P8KP26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS00270
gene id: 1850254:LPB137_RS00270
uniprot id: A0A1P8KIM5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1850254:LPB137 RS11945
gene id: 1850254:LPB137_RS11945
uniprot id: A0A1P8KPN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1850254:LPB137 RS10150
gene id: 1850254:LPB137_RS10150
uniprot id: A0A1P8KNL1
names: Similarity
messages: Belongs to the glutamate synthase family.

1850254:LPB137 RS04685
gene id: 1850254:LPB137_RS04685
uniprot id: A0A1P8KKV9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1850254:LPB137 RS02800
gene id: 1850254:LPB137_RS02800
uniprot id: A0A1P8KJY4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1850254:LPB137 RS01585
gene id: 1850254:LPB137_RS01585
uniprot id: A0A1P8KJ96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1850254:LPB137 RS04810
gene id: 1850254:LPB137_RS04810
uniprot id: A0A1P8KKZ2
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS12125
gene id: 1850254:LPB137_RS12125
uniprot id: A0A1P8KPU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS10890
gene id: 1850254:LPB137_RS10890
uniprot id: A0A1P8KP35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1850254:LPB137 RS02185
gene id: 1850254:LPB137_RS02185
uniprot id: A0A1P8KJL9
names: Similarity
messages: Belongs to the leucine-binding protein family.

1850254:LPB137 RS02005
gene id: 1850254:LPB137_RS02005
uniprot id: A0A1P8KJG5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1850254:LPB137 RS10820
gene id: 1850254:LPB137_RS10820
uniprot id: A0A1P8KP61
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1850254:LPB137 RS03205
gene id: 1850254:LPB137_RS03205
uniprot id: A0A1P8KK32
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1850254:LPB137 RS13595
gene id: 1850254:LPB137_RS13595
uniprot id: A0A1P8KQD0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS08190
gene id: 1850254:LPB137_RS08190
uniprot id: A0A1P8KMQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1850254:LPB137 RS03160
gene id: 1850254:LPB137_RS03160
uniprot id: A0A1P8KK20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1850254:LPB137 RS13200
gene id: 1850254:LPB137_RS13200
uniprot id: A0A1P8KQA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1850254:LPB137 RS07310
gene id: 1850254:LPB137_RS07310
uniprot id: A0A1P8KMA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS11550
gene id: 1850254:LPB137_RS11550
uniprot id: A0A1P8KPB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS08905
gene id: 1850254:LPB137_RS08905
uniprot id: A0A1P8KN54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS00825
gene id: 1850254:LPB137_RS00825
uniprot id: A0A1P8KIU8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1850254:LPB137 RS01360
gene id: 1850254:LPB137_RS01360
uniprot id: A0A1P8KJ48
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS04510
gene id: 1850254:LPB137_RS04510
uniprot id: A0A1P8KKT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1850254:LPB137 RS07535
gene id: 1850254:LPB137_RS07535
uniprot id: A0A1P8KMD0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1850254:LPB137 RS10135
gene id: 1850254:LPB137_RS10135
uniprot id: A0A1P8KNQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1850254:LPB137 RS01625
gene id: 1850254:LPB137_RS01625
uniprot id: A0A1P8KJA3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1850254:LPB137 RS12785
gene id: 1850254:LPB137_RS12785
uniprot id: A0A1P8KQ76
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1850254:LPB137 RS02440
gene id: 1850254:LPB137_RS02440
uniprot id: A0A1P8KJT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS07140
gene id: 1850254:LPB137_RS07140
uniprot id: A0A1P8KM50
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1850254:LPB137 RS12500
gene id: 1850254:LPB137_RS12500
uniprot id: A0A1P8KQ00
names: Similarity
messages: Belongs to the DprA/Smf family.

1850254:LPB137 RS06355
gene id: 1850254:LPB137_RS06355
uniprot id: A0A1P8KLQ4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850254:LPB137 RS06655
gene id: 1850254:LPB137_RS06655
uniprot id: A0A1P8KM03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1850254:LPB137 RS06185
gene id: 1850254:LPB137_RS06185
uniprot id: A0A1P8KLQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1850254:LPB137 RS01770
gene id: 1850254:LPB137_RS01770
uniprot id: A0A1P8KJD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1850254:LPB137 RS13290
gene id: 1850254:LPB137_RS13290
uniprot id: A0A1P8KQ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1850254:LPB137 RS11590
gene id: 1850254:LPB137_RS11590
uniprot id: A0A1P8KPH7
names: Similarity
messages: Belongs to the YciI family.

1850254:LPB137 RS12545
gene id: 1850254:LPB137_RS12545
uniprot id: A0A1P8KPT4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1850254:LPB137 RS07800
gene id: 1850254:LPB137_RS07800
uniprot id: A0A1P8KR22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1850254:LPB137 RS06725
gene id: 1850254:LPB137_RS06725
uniprot id: A0A1P8KLY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1850254:LPB137 RS06750
gene id: 1850254:LPB137_RS06750
uniprot id: A0A1P8KLZ9
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Homodimer.

1850254:LPB137 RS04560
gene id: 1850254:LPB137_RS04560
uniprot id: A0A1P8KKU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1850254:LPB137 RS04630
gene id: 1850254:LPB137_RS04630
uniprot id: A0A1P8KKU7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1850254:LPB137 RS09825
gene id: 1850254:LPB137_RS09825
uniprot id: A0A1P8KNL2
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1850254:LPB137 RS03865
gene id: 1850254:LPB137_RS03865
uniprot id: A0A1P8KKE5
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS04925
gene id: 1850254:LPB137_RS04925
uniprot id: A0A1P8KKZ4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1850254:LPB137 RS12570
gene id: 1850254:LPB137_RS12570
uniprot id: A0A1P8KQ46
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1850254:LPB137 RS03040
gene id: 1850254:LPB137_RS03040
uniprot id: A0A1P8KK23
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1850254:LPB137 RS03280
gene id: 1850254:LPB137_RS03280
uniprot id: A0A1P8KK55
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1850254:LPB137 RS10745
gene id: 1850254:LPB137_RS10745
uniprot id: A0A1P8KP13
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS10680
gene id: 1850254:LPB137_RS10680
uniprot id: A0A1P8KP05
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS11185
gene id: 1850254:LPB137_RS11185
uniprot id: A0A1P8KP94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1850254:LPB137 RS10845
gene id: 1850254:LPB137_RS10845
uniprot id: A0A1P8KP34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1850254:LPB137 RS11385
gene id: 1850254:LPB137_RS11385
uniprot id: A0A1P8KPD5
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1850254:LPB137 RS06150
gene id: 1850254:LPB137_RS06150
uniprot id: A0A1P8KLP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1850254:LPB137 RS00420
gene id: 1850254:LPB137_RS00420
uniprot id: A0A1P8KIN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1850254:LPB137 RS01785
gene id: 1850254:LPB137_RS01785
uniprot id: A0A1P8KJE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1850254:LPB137 RS13720
gene id: 1850254:LPB137_RS13720
uniprot id: A0A1P8KQF1
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS11045
gene id: 1850254:LPB137_RS11045
uniprot id: A0A1P8KP89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

1850254:LPB137 RS03695
gene id: 1850254:LPB137_RS03695
uniprot id: A0A1P8KKC8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1850254:LPB137 RS08645
gene id: 1850254:LPB137_RS08645
uniprot id: A0A1P8KN32
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1850254:LPB137 RS12385
gene id: 1850254:LPB137_RS12385
uniprot id: A0A1P8KPQ6
names: Similarity
messages: Belongs to the UPF0102 family.

1850254:LPB137 RS13055
gene id: 1850254:LPB137_RS13055
uniprot id: A0A1P8KQB0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS12000
gene id: 1850254:LPB137_RS12000
uniprot id: A0A1P8KPU8
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS04285
gene id: 1850254:LPB137_RS04285
uniprot id: A0A1P8KKM4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS05885
gene id: 1850254:LPB137_RS05885
uniprot id: A0A1P8KLI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS09465
gene id: 1850254:LPB137_RS09465
uniprot id: A0A1P8KNG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1850254:LPB137 RS07510
gene id: 1850254:LPB137_RS07510
uniprot id: A0A1P8KMB4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1850254:LPB137 RS09860
gene id: 1850254:LPB137_RS09860
uniprot id: A0A1P8KNM5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1850254:LPB137 RS09280
gene id: 1850254:LPB137_RS09280
uniprot id: A0A1P8KN83
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1850254:LPB137 RS03965
gene id: 1850254:LPB137_RS03965
uniprot id: A0A1P8KKH7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1850254:LPB137 RS00810
gene id: 1850254:LPB137_RS00810
uniprot id: A0A1P8KIU6
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1850254:LPB137 RS03900
gene id: 1850254:LPB137_RS03900
uniprot id: A0A1P8KKF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1850254:LPB137 RS10510
gene id: 1850254:LPB137_RS10510
uniprot id: A0A1P8KNW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS07110
gene id: 1850254:LPB137_RS07110
uniprot id: A0A1P8KM49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1850254:LPB137 RS06670
gene id: 1850254:LPB137_RS06670
uniprot id: A0A1P8KLX6
names: Similarity
messages: Belongs to the XseB family.

1850254:LPB137 RS06665
gene id: 1850254:LPB137_RS06665
uniprot id: A0A1P8KLX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1850254:LPB137 RS12465
gene id: 1850254:LPB137_RS12465
uniprot id: A0A1P8KPX6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1850254:LPB137 RS09380
gene id: 1850254:LPB137_RS09380
uniprot id: A0A1P8KNA3
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1850254:LPB137 RS10220
gene id: 1850254:LPB137_RS10220
uniprot id: A0A1P8KNT9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850254:LPB137 RS13325
gene id: 1850254:LPB137_RS13325
uniprot id: A0A1P8KQH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1850254:LPB137 RS12795
gene id: 1850254:LPB137_RS12795
uniprot id: A0A1P8KQ81
names: Similarity
messages: Belongs to the UreD family.

1850254:LPB137 RS02165
gene id: 1850254:LPB137_RS02165
uniprot id: A0A1P8KJJ6
names: Similarity
messages: Belongs to the proline racemase family.

1850254:LPB137 RS01495
gene id: 1850254:LPB137_RS01495
uniprot id: A0A1P8KJ88
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1850254:LPB137 RS06805
gene id: 1850254:LPB137_RS06805
uniprot id: A0A1P8KM11
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS10900
gene id: 1850254:LPB137_RS10900
uniprot id: A0A1P8KPA2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1850254:LPB137 RS03095
gene id: 1850254:LPB137_RS03095
uniprot id: A0A1P8KK34
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1850254:LPB137 RS01275
gene id: 1850254:LPB137_RS01275
uniprot id: A0A1P8KJ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1850254:LPB137 RS09580
gene id: 1850254:LPB137_RS09580
uniprot id: A0A1P8KNF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1850254:LPB137 RS13625
gene id: 1850254:LPB137_RS13625
uniprot id: A0A1P8KQM4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS05370
gene id: 1850254:LPB137_RS05370
uniprot id: A0A1P8KL99
names: Similarity
messages: Belongs to the LOG family.

1850254:LPB137 RS09830
gene id: 1850254:LPB137_RS09830
uniprot id: A0A1P8KNH6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1850254:LPB137 RS12675
gene id: 1850254:LPB137_RS12675
uniprot id: A0A1P8KQ34
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS00795
gene id: 1850254:LPB137_RS00795
uniprot id: A0A1P8KIW0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS08555
gene id: 1850254:LPB137_RS08555
uniprot id: A0A1P8KN07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1850254:LPB137 RS14635
gene id: 1850254:LPB137_RS14635
uniprot id: A0A1P8KNY0
names: Subcellular Location Annotation
messages: Secreted

1850254:LPB137 RS07695
gene id: 1850254:LPB137_RS07695
uniprot id: A0A1P8KMG0
names: Similarity
messages: Belongs to the HypE family.

1850254:LPB137 RS01210
gene id: 1850254:LPB137_RS01210
uniprot id: A0A1P8KJ23
names: Similarity
messages: Belongs to the SUI1 family.

1850254:LPB137 RS00065
gene id: 1850254:LPB137_RS00065
uniprot id: A0A1P8KII1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1850254:LPB137 RS07205
gene id: 1850254:LPB137_RS07205
uniprot id: A0A1P8KM78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1850254:LPB137 RS11600
gene id: 1850254:LPB137_RS11600
uniprot id: A0A1P8KPC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1850254:LPB137 RS03050
gene id: 1850254:LPB137_RS03050
uniprot id: A0A1P8KK05
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1850254:LPB137 RS07995
gene id: 1850254:LPB137_RS07995
uniprot id: A0A1P8KMK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1850254:LPB137 RS00960
gene id: 1850254:LPB137_RS00960
uniprot id: A0A1P8KIX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1850254:LPB137 RS13410
gene id: 1850254:LPB137_RS13410
uniprot id: A0A1P8KQE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1850254:LPB137 RS12595
gene id: 1850254:LPB137_RS12595
uniprot id: A0A1P8KPU5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1850254:LPB137 RS03950
gene id: 1850254:LPB137_RS03950
uniprot id: A0A1P8KKG2
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS02645
gene id: 1850254:LPB137_RS02645
uniprot id: A0A1P8KJT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1850254:LPB137 RS14685
gene id: 1850254:LPB137_RS14685
uniprot id: A0A1P8KQD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1850254:LPB137 RS02950
gene id: 1850254:LPB137_RS02950
uniprot id: A0A1P8KJZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1850254:LPB137 RS10225
gene id: 1850254:LPB137_RS10225
uniprot id: A0A1P8KNR5
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS11130
gene id: 1850254:LPB137_RS11130
uniprot id: A0A1P8KPC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1850254:LPB137 RS08025
gene id: 1850254:LPB137_RS08025
uniprot id: A0A1P8KMR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS04590
gene id: 1850254:LPB137_RS04590
uniprot id: A0A1P8KKV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1850254:LPB137 RS04965
gene id: 1850254:LPB137_RS04965
uniprot id: A0A1P8KL20
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850254:LPB137 RS12165
gene id: 1850254:LPB137_RS12165
uniprot id: A0A1P8KPW1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1850254:LPB137 RS03215
gene id: 1850254:LPB137_RS03215
uniprot id: A0A1P8KK61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1850254:LPB137 RS10280
gene id: 1850254:LPB137_RS10280
uniprot id: A0A1P8KNS8
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS11400
gene id: 1850254:LPB137_RS11400
uniprot id: A0A1P8KPH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1850254:LPB137 RS04250
gene id: 1850254:LPB137_RS04250
uniprot id: A0A1P8KKR2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS04855
gene id: 1850254:LPB137_RS04855
uniprot id: A0A1P8KKZ7
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS03925
gene id: 1850254:LPB137_RS03925
uniprot id: A0A1P8KKF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1850254:LPB137 RS08935
gene id: 1850254:LPB137_RS08935
uniprot id: A0A1P8KN65
names: Similarity
messages: Belongs to the catalase family.

1850254:LPB137 RS13270
gene id: 1850254:LPB137_RS13270
uniprot id: A0A1P8KQE8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1850254:LPB137 RS10360
gene id: 1850254:LPB137_RS10360
uniprot id: A0A1P8KNT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1850254:LPB137 RS11355
gene id: 1850254:LPB137_RS11355
uniprot id: A0A1P8KP70
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1850254:LPB137 RS01960
gene id: 1850254:LPB137_RS01960
uniprot id: A0A1P8KJF4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1850254:LPB137 RS12020
gene id: 1850254:LPB137_RS12020
uniprot id: A0A1P8KPS8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1850254:LPB137 RS09780
gene id: 1850254:LPB137_RS09780
uniprot id: A0A1P8KNG8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS02470
gene id: 1850254:LPB137_RS02470
uniprot id: A0A1P8KJR5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1850254:LPB137 RS13315
gene id: 1850254:LPB137_RS13315
uniprot id: A0A1P8KQF7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS03220
gene id: 1850254:LPB137_RS03220
uniprot id: A0A1P8KK66
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850254:LPB137 RS04235
gene id: 1850254:LPB137_RS04235
uniprot id: A0A1P8KKL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1850254:LPB137 RS02525
gene id: 1850254:LPB137_RS02525
uniprot id: A0A1P8KJS5
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS13525
gene id: 1850254:LPB137_RS13525
uniprot id: A0A1P8KQK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1850254:LPB137 RS13490
gene id: 1850254:LPB137_RS13490
uniprot id: A0A1P8KQK2
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS12455
gene id: 1850254:LPB137_RS12455
uniprot id: A0A1P8KPY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1850254:LPB137 RS07840
gene id: 1850254:LPB137_RS07840
uniprot id: A0A1P8KML5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1850254:LPB137 RS11090
gene id: 1850254:LPB137_RS11090
uniprot id: A0A1P8KPA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1850254:LPB137 RS01445
gene id: 1850254:LPB137_RS01445
uniprot id: A0A1P8KJ79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

1850254:LPB137 RS12220
gene id: 1850254:LPB137_RS12220
uniprot id: A0A1P8KPM6
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1850254:LPB137 RS07845
gene id: 1850254:LPB137_RS07845
uniprot id: A0A1P8KMN9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850254:LPB137 RS00370
gene id: 1850254:LPB137_RS00370
uniprot id: A0A1P8KIL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1850254:LPB137 RS12685
gene id: 1850254:LPB137_RS12685
uniprot id: A0A1P8KR47
names: Subcellular Location Annotation
messages: Membrane

1850254:LPB137 RS11250
gene id: 1850254:LPB137_RS11250
uniprot id: A0A1P8KPD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

1850254:LPB137 RS10125
gene id: 1850254:LPB137_RS10125
uniprot id: A0A1P8KNW2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1850254:LPB137 RS03270
gene id: 1850254:LPB137_RS03270
uniprot id: A0A1P8KK76
names: Similarity
messages: Belongs to the peptidase S49 family.

1850254:LPB137 RS11300
gene id: 1850254:LPB137_RS11300
uniprot id: A0A1P8KPE7
names: Similarity
messages: Belongs to the MotB family.

1850254:LPB137 RS03110
gene id: 1850254:LPB137_RS03110
uniprot id: A0A1P8KK10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1850254:LPB137 RS00450
gene id: 1850254:LPB137_RS00450
uniprot id: A0A1P8KIM7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1850254:LPB137 RS12490
gene id: 1850254:LPB137_RS12490
uniprot id: A0A1P8KQ21
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850254:LPB137 RS07105
gene id: 1850254:LPB137_RS07105
uniprot id: A0A1P8KM47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1850254:LPB137 RS10825
gene id: 1850254:LPB137_RS10825
uniprot id: A0A1P8KNX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1850254:LPB137 RS12275
gene id: 1850254:LPB137_RS12275
uniprot id: A0A1P8KPN7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1850254:LPB137 RS12255
gene id: 1850254:LPB137_RS12255
uniprot id: A0A1P8KQ05
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1850254:LPB137 RS09505
gene id: 1850254:LPB137_RS09505
uniprot id: A0A1P8KNH7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1850254:LPB137 RS03740
gene id: 1850254:LPB137_RS03740
uniprot id: A0A1P8KKD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1850254:LPB137 RS10885
gene id: 1850254:LPB137_RS10885
uniprot id: A0A1P8KP58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1850254:LPB137 RS11565
gene id: 1850254:LPB137_RS11565
uniprot id: A0A1P8KPH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1850254:LPB137 RS13970
gene id: 1850254:LPB137_RS13970
uniprot id: A0A1P8KQR2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.