1850252:LPB136 RS07525
gene id: 1850252:LPB136_RS07525
uniprot id: A0A1L3JMY6
names: Similarity
messages: Belongs to the arginase family.

1850252:LPB136 RS09790
gene id: 1850252:LPB136_RS09790
uniprot id: A0A1L3JMT0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1850252:LPB136 RS03090
gene id: 1850252:LPB136_RS03090
uniprot id: A0A1L3JH01
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1850252:LPB136 RS01270
gene id: 1850252:LPB136_RS01270
uniprot id: A0A1L3JG12
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS08480
gene id: 1850252:LPB136_RS08480
uniprot id: A0A1L3JJU5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1850252:LPB136 RS07210
gene id: 1850252:LPB136_RS07210
uniprot id: A0A1L3JMW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1850252:LPB136 RS11885
gene id: 1850252:LPB136_RS11885
uniprot id: A0A1L3JLP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1850252:LPB136 RS09255
gene id: 1850252:LPB136_RS09255
uniprot id: A0A1L3JK33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1850252:LPB136 RS10365
gene id: 1850252:LPB136_RS10365
uniprot id: A0A1L3JKV9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1850252:LPB136 RS09640
gene id: 1850252:LPB136_RS09640
uniprot id: A0A1L3JKF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1850252:LPB136 RS02295
gene id: 1850252:LPB136_RS02295
uniprot id: A0A1L3JGL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1850252:LPB136 RS05255
gene id: 1850252:LPB136_RS05255
uniprot id: A0A1L3JMV6
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS05875
gene id: 1850252:LPB136_RS05875
uniprot id: A0A1L3JIG3
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS10905
gene id: 1850252:LPB136_RS10905
uniprot id: A0A1L3JL54
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1850252:LPB136 RS07940
gene id: 1850252:LPB136_RS07940
uniprot id: A0A1L3JJF9
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1850252:LPB136 RS10160
gene id: 1850252:LPB136_RS10160
uniprot id: A0A1L3JKT5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1850252:LPB136 RS00375
gene id: 1850252:LPB136_RS00375
uniprot id: A0A1L3JFK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1850252:LPB136 RS12200
gene id: 1850252:LPB136_RS12200
uniprot id: A0A1L3JLV6
names: Similarity
messages: Belongs to the pyruvate kinase family.

1850252:LPB136 RS00545
gene id: 1850252:LPB136_RS00545
uniprot id: A0A1L3JFP0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1850252:LPB136 RS03840
gene id: 1850252:LPB136_RS03840
uniprot id: A0A1L3JHJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1850252:LPB136 RS11280
gene id: 1850252:LPB136_RS11280
uniprot id: A0A1L3JLC2
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1850252:LPB136 RS02990
gene id: 1850252:LPB136_RS02990
uniprot id: A0A1L3JGY4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1850252:LPB136 RS05230
gene id: 1850252:LPB136_RS05230
uniprot id: A0A1L3JI49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1850252:LPB136 RS01735
gene id: 1850252:LPB136_RS01735
uniprot id: A0A1L3JGB1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1850252:LPB136 RS09400
gene id: 1850252:LPB136_RS09400
uniprot id: A0A1L3JKC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS12970
gene id: 1850252:LPB136_RS12970
uniprot id: A0A1L3JN04
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS07290
gene id: 1850252:LPB136_RS07290
uniprot id: A0A1L3JMR8
names: Similarity
messages: Belongs to the LOG family.

1850252:LPB136 RS03475
gene id: 1850252:LPB136_RS03475
uniprot id: A0A1L3JH49
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS10050
gene id: 1850252:LPB136_RS10050
uniprot id: A0A1L3JKP8
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1850252:LPB136 RS06335
gene id: 1850252:LPB136_RS06335
uniprot id: A0A1L3JIN9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1850252:LPB136 RS10075
gene id: 1850252:LPB136_RS10075
uniprot id: A0A1L3JKN2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1850252:LPB136 RS05390
gene id: 1850252:LPB136_RS05390
uniprot id: A0A1L3JI89
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS12910
gene id: 1850252:LPB136_RS12910
uniprot id: A0A1L3JM48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1850252:LPB136 RS08215
gene id: 1850252:LPB136_RS08215
uniprot id: A0A1L3JJP2
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1850252:LPB136 RS07830
gene id: 1850252:LPB136_RS07830
uniprot id: A0A1L3JJG6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1850252:LPB136 RS09625
gene id: 1850252:LPB136_RS09625
uniprot id: A0A1L3JKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1850252:LPB136 RS05070
gene id: 1850252:LPB136_RS05070
uniprot id: A0A1L3JI05
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS05655
gene id: 1850252:LPB136_RS05655
uniprot id: A0A1L3JIC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1850252:LPB136 RS11795
gene id: 1850252:LPB136_RS11795
uniprot id: A0A1L3JLG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS01305
gene id: 1850252:LPB136_RS01305
uniprot id: A0A1L3JG19
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS04565
gene id: 1850252:LPB136_RS04565
uniprot id: A0A1L3JHT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1850252:LPB136 RS04120
gene id: 1850252:LPB136_RS04120
uniprot id: A0A1L3JHJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1850252:LPB136 RS04185
gene id: 1850252:LPB136_RS04185
uniprot id: A0A1L3JHL3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

1850252:LPB136 RS02955
gene id: 1850252:LPB136_RS02955
uniprot id: A0A1L3JGZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1850252:LPB136 RS09700
gene id: 1850252:LPB136_RS09700
uniprot id: A0A1L3JKG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1850252:LPB136 RS12230
gene id: 1850252:LPB136_RS12230
uniprot id: A0A1L3JLV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

1850252:LPB136 RS12225
gene id: 1850252:LPB136_RS12225
uniprot id: A0A1L3JLS6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS08090
gene id: 1850252:LPB136_RS08090
uniprot id: A0A1L3JJL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1850252:LPB136 RS06825
gene id: 1850252:LPB136_RS06825
uniprot id: A0A1L3JIV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1850252:LPB136 RS09890
gene id: 1850252:LPB136_RS09890
uniprot id: A0A1L3JKH1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1850252:LPB136 RS00575
gene id: 1850252:LPB136_RS00575
uniprot id: A0A1L3JFR3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1850252:LPB136 RS02345
gene id: 1850252:LPB136_RS02345
uniprot id: A0A1L3JGM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1850252:LPB136 RS12470
gene id: 1850252:LPB136_RS12470
uniprot id: A0A1L3JM09
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1850252:LPB136 RS05780
gene id: 1850252:LPB136_RS05780
uniprot id: A0A1L3JIC7
names: Similarity
messages: Belongs to the DinB family.

1850252:LPB136 RS06315
gene id: 1850252:LPB136_RS06315
uniprot id: A0A1L3JIP1
names: Subunit
messages: Homodimer.

1850252:LPB136 RS13125
gene id: 1850252:LPB136_RS13125
uniprot id: A0A1L3JM90
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS01610
gene id: 1850252:LPB136_RS01610
uniprot id: A0A1L3JG90
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850252:LPB136 RS11920
gene id: 1850252:LPB136_RS11920
uniprot id: A0A1L3JLM7
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS07095
gene id: 1850252:LPB136_RS07095
uniprot id: A0A1L3JJ54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1850252:LPB136 RS10200
gene id: 1850252:LPB136_RS10200
uniprot id: A0A1L3JKS4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1850252:LPB136 RS09985
gene id: 1850252:LPB136_RS09985
uniprot id: A0A1L3JKH9
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS10780
gene id: 1850252:LPB136_RS10780
uniprot id: A0A1L3JMW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS01350
gene id: 1850252:LPB136_RS01350
uniprot id: A0A1L3JG99
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1850252:LPB136 RS09390
gene id: 1850252:LPB136_RS09390
uniprot id: A0A1L3JK68
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS10515
gene id: 1850252:LPB136_RS10515
uniprot id: A0A1L3JKW1
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1850252:LPB136 RS09315
gene id: 1850252:LPB136_RS09315
uniprot id: A0A1L3JK60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1850252:LPB136 RS08535
gene id: 1850252:LPB136_RS08535
uniprot id: A0A1L3JJS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1850252:LPB136 RS01680
gene id: 1850252:LPB136_RS01680
uniprot id: A0A1L3JGA3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1850252:LPB136 RS02130
gene id: 1850252:LPB136_RS02130
uniprot id: A0A1L3JGI1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1850252:LPB136 RS11575
gene id: 1850252:LPB136_RS11575
uniprot id: A0A1L3JLI8
names: Similarity
messages: Belongs to the peptidase S8 family.

1850252:LPB136 RS06690
gene id: 1850252:LPB136_RS06690
uniprot id: A0A1L3JIT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1850252:LPB136 RS09970
gene id: 1850252:LPB136_RS09970
uniprot id: A0A1L3JKL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1850252:LPB136 RS07720
gene id: 1850252:LPB136_RS07720
uniprot id: A0A1L3JJG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1850252:LPB136 RS07930
gene id: 1850252:LPB136_RS07930
uniprot id: A0A1L3JJI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS10135
gene id: 1850252:LPB136_RS10135
uniprot id: A0A1L3JKN9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1850252:LPB136 RS10340
gene id: 1850252:LPB136_RS10340
uniprot id: A0A1L3JKR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS13245
gene id: 1850252:LPB136_RS13245
uniprot id: A0A1L3JMF7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1850252:LPB136 RS02105
gene id: 1850252:LPB136_RS02105
uniprot id: A0A1L3JGI7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1850252:LPB136 RS04015
gene id: 1850252:LPB136_RS04015
uniprot id: A0A1L3JHI2
names: Similarity
messages: Belongs to the peptidase M24B family.

1850252:LPB136 RS09915
gene id: 1850252:LPB136_RS09915
uniprot id: A0A1L3JKH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1850252:LPB136 RS02735
gene id: 1850252:LPB136_RS02735
uniprot id: A0A1L3JGV5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1850252:LPB136 RS09110
gene id: 1850252:LPB136_RS09110
uniprot id: A0A1L3JK23
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1850252:LPB136 RS01235
gene id: 1850252:LPB136_RS01235
uniprot id: A0A1L3JG05
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1850252:LPB136 RS11850
gene id: 1850252:LPB136_RS11850
uniprot id: A0A1L3JLK1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1850252:LPB136 RS11470
gene id: 1850252:LPB136_RS11470
uniprot id: A0A1L3JLG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS06775
gene id: 1850252:LPB136_RS06775
uniprot id: A0A1L3JIZ3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS01365
gene id: 1850252:LPB136_RS01365
uniprot id: A0A1L3JG50
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1850252:LPB136 RS11965
gene id: 1850252:LPB136_RS11965
uniprot id: A0A1L3JLK7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS06830
gene id: 1850252:LPB136_RS06830
uniprot id: A0A1L3JJ03
names: Similarity
messages: Belongs to the AIR synthase family.

1850252:LPB136 RS11955
gene id: 1850252:LPB136_RS11955
uniprot id: A0A1L3JLM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1850252:LPB136 RS01225
gene id: 1850252:LPB136_RS01225
uniprot id: A0A1L3JG28
names: Subcellular Location Annotation
messages: Secreted

1850252:LPB136 RS02670
gene id: 1850252:LPB136_RS02670
uniprot id: A0A1L3JGT2
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS09980
gene id: 1850252:LPB136_RS09980
uniprot id: A0A1L3JKL2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1850252:LPB136 RS07675
gene id: 1850252:LPB136_RS07675
uniprot id: A0A1L3JJD5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1850252:LPB136 RS07765
gene id: 1850252:LPB136_RS07765
uniprot id: A0A1L3JJC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1850252:LPB136 RS06225
gene id: 1850252:LPB136_RS06225
uniprot id: A0A1L3JIM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1850252:LPB136 RS12870
gene id: 1850252:LPB136_RS12870
uniprot id: A0A1L3JM23
names: Subcellular Location Annotation
messages: Periplasm

1850252:LPB136 RS12455
gene id: 1850252:LPB136_RS12455
uniprot id: A0A1L3JM04
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1850252:LPB136 RS00030
gene id: 1850252:LPB136_RS00030
uniprot id: A0A1L3JFE2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850252:LPB136 RS00550
gene id: 1850252:LPB136_RS00550
uniprot id: A0A1L3JFQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS01930
gene id: 1850252:LPB136_RS01930
uniprot id: A0A1L3JGD2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1850252:LPB136 RS01585
gene id: 1850252:LPB136_RS01585
uniprot id: A0A1L3JG68
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1850252:LPB136 RS12960
gene id: 1850252:LPB136_RS12960
uniprot id: A0A1L3JM57
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1850252:LPB136 RS08400
gene id: 1850252:LPB136_RS08400
uniprot id: A0A1L3JJU9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1850252:LPB136 RS02285
gene id: 1850252:LPB136_RS02285
uniprot id: A0A1L3JGL3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850252:LPB136 RS04995
gene id: 1850252:LPB136_RS04995
uniprot id: A0A1L3JHY5
names: Similarity
messages: Belongs to the SUI1 family.

1850252:LPB136 RS05395
gene id: 1850252:LPB136_RS05395
uniprot id: A0A1L3JIB9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850252:LPB136 RS11675
gene id: 1850252:LPB136_RS11675
uniprot id: A0A1L3JLJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1850252:LPB136 RS05080
gene id: 1850252:LPB136_RS05080
uniprot id: A0A1L3JI26
names: Similarity
messages: Belongs to the peptidase S51 family.

1850252:LPB136 RS06635
gene id: 1850252:LPB136_RS06635
uniprot id: A0A1L3JMS2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1850252:LPB136 RS08940
gene id: 1850252:LPB136_RS08940
uniprot id: A0A1L3JK45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850252:LPB136 RS07385
gene id: 1850252:LPB136_RS07385
uniprot id: A0A1L3JJ57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1850252:LPB136 RS06965
gene id: 1850252:LPB136_RS06965
uniprot id: A0A1L3JIX2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1850252:LPB136 RS09095
gene id: 1850252:LPB136_RS09095
uniprot id: A0A1L3JK77
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1850252:LPB136 RS11580
gene id: 1850252:LPB136_RS11580
uniprot id: A0A1L3JLI6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1850252:LPB136 RS12560
gene id: 1850252:LPB136_RS12560
uniprot id: A0A1L3JLW2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1850252:LPB136 RS11375
gene id: 1850252:LPB136_RS11375
uniprot id: A0A1L3JLB5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850252:LPB136 RS11545
gene id: 1850252:LPB136_RS11545
uniprot id: A0A1L3JLE1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS11665
gene id: 1850252:LPB136_RS11665
uniprot id: A0A1L3JLE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1850252:LPB136 RS01250
gene id: 1850252:LPB136_RS01250
uniprot id: A0A1L3JG38
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1850252:LPB136 RS02095
gene id: 1850252:LPB136_RS02095
uniprot id: A0A1L3JGG3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1850252:LPB136 RS09830
gene id: 1850252:LPB136_RS09830
uniprot id: A0A1L3JKM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

1850252:LPB136 RS12615
gene id: 1850252:LPB136_RS12615
uniprot id: A0A1L3JM00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1850252:LPB136 RS02470
gene id: 1850252:LPB136_RS02470
uniprot id: A0A1L3JGQ1
names: Similarity
messages: Belongs to the NusB family.

1850252:LPB136 RS04435
gene id: 1850252:LPB136_RS04435
uniprot id: A0A1L3JHV5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1850252:LPB136 RS04180
gene id: 1850252:LPB136_RS04180
uniprot id: A0A1L3JHK6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1850252:LPB136 RS09870
gene id: 1850252:LPB136_RS09870
uniprot id: A0A1L3JKL0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1850252:LPB136 RS06405
gene id: 1850252:LPB136_RS06405
uniprot id: A0A1L3JIT1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS06170
gene id: 1850252:LPB136_RS06170
uniprot id: A0A1L3JIJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1850252:LPB136 RS13295
gene id: 1850252:LPB136_RS13295
uniprot id: A0A1L3JMB0
names: Subcellular Location Annotation
messages: Cytoplasm

1850252:LPB136 RS07655
gene id: 1850252:LPB136_RS07655
uniprot id: A0A1L3JJ99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1850252:LPB136 RS07915
gene id: 1850252:LPB136_RS07915
uniprot id: A0A1L3JJF6
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1850252:LPB136 RS05535
gene id: 1850252:LPB136_RS05535
uniprot id: A0A1L3JIA3
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS06035
gene id: 1850252:LPB136_RS06035
uniprot id: A0A1L3JIJ4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1850252:LPB136 RS07800
gene id: 1850252:LPB136_RS07800
uniprot id: A0A1L3JJE2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS03870
gene id: 1850252:LPB136_RS03870
uniprot id: A0A1L3JHF7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1850252:LPB136 RS08155
gene id: 1850252:LPB136_RS08155
uniprot id: A0A1L3JJN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1850252:LPB136 RS02460
gene id: 1850252:LPB136_RS02460
uniprot id: A0A1L3JGM8
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS03040
gene id: 1850252:LPB136_RS03040
uniprot id: A0A1L3JH09
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1850252:LPB136 RS05075
gene id: 1850252:LPB136_RS05075
uniprot id: A0A1L3JHZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1850252:LPB136 RS11975
gene id: 1850252:LPB136_RS11975
uniprot id: A0A1L3JLP1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1850252:LPB136 RS11680
gene id: 1850252:LPB136_RS11680
uniprot id: A0A1L3JLK6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS11510
gene id: 1850252:LPB136_RS11510
uniprot id: A0A1L3JLE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1850252:LPB136 RS00760
gene id: 1850252:LPB136_RS00760
uniprot id: A0A1L3JFY4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1850252:LPB136 RS04595
gene id: 1850252:LPB136_RS04595
uniprot id: A0A1L3JHR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1850252:LPB136 RS00165
gene id: 1850252:LPB136_RS00165
uniprot id: A0A1L3JFG6
names: Similarity
messages: Belongs to the UPF0758 family.

1850252:LPB136 RS13190
gene id: 1850252:LPB136_RS13190
uniprot id: A0A1L3JM83
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1850252:LPB136 RS03845
gene id: 1850252:LPB136_RS03845
uniprot id: A0A1L3JHG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1850252:LPB136 RS07795
gene id: 1850252:LPB136_RS07795
uniprot id: A0A1L3JJG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS03350
gene id: 1850252:LPB136_RS03350
uniprot id: A0A1L3JH59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1850252:LPB136 RS00045
gene id: 1850252:LPB136_RS00045
uniprot id: A0A1L3JMI4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1850252:LPB136 RS00635
gene id: 1850252:LPB136_RS00635
uniprot id: A0A1L3JFQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1850252:LPB136 RS02680
gene id: 1850252:LPB136_RS02680
uniprot id: A0A1L3JGR5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1850252:LPB136 RS02335
gene id: 1850252:LPB136_RS02335
uniprot id: A0A1L3JGM3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1850252:LPB136 RS10235
gene id: 1850252:LPB136_RS10235
uniprot id: A0A1L3JKR8
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1850252:LPB136 RS04130
gene id: 1850252:LPB136_RS04130
uniprot id: A0A1L3JHI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1850252:LPB136 RS08410
gene id: 1850252:LPB136_RS08410
uniprot id: A0A1L3JJN4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS07180
gene id: 1850252:LPB136_RS07180
uniprot id: A0A1L3JJ31
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1850252:LPB136 RS10570
gene id: 1850252:LPB136_RS10570
uniprot id: A0A1L3JKZ6
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS08930
gene id: 1850252:LPB136_RS08930
uniprot id: A0A1L3JK32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850252:LPB136 RS06175
gene id: 1850252:LPB136_RS06175
uniprot id: A0A1L3JIN6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1850252:LPB136 RS04265
gene id: 1850252:LPB136_RS04265
uniprot id: A0A1L3JHS1
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1850252:LPB136 RS12465
gene id: 1850252:LPB136_RS12465
uniprot id: A0A1L3JMX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1850252:LPB136 RS09115
gene id: 1850252:LPB136_RS09115
uniprot id: A0A1L3JK42
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1850252:LPB136 RS00265
gene id: 1850252:LPB136_RS00265
uniprot id: A0A1L3JFI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1850252:LPB136 RS11530
gene id: 1850252:LPB136_RS11530
uniprot id: A0A1L3JLH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1850252:LPB136 RS00200
gene id: 1850252:LPB136_RS00200
uniprot id: A0A1L3JFH5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1850252:LPB136 RS07840
gene id: 1850252:LPB136_RS07840
uniprot id: A0A1L3JJE1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1850252:LPB136 RS12710
gene id: 1850252:LPB136_RS12710
uniprot id: A0A1L3JLZ0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1850252:LPB136 RS10850
gene id: 1850252:LPB136_RS10850
uniprot id: A0A1L3JL22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1850252:LPB136 RS06025
gene id: 1850252:LPB136_RS06025
uniprot id: A0A1L3JIH0
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1850252:LPB136 RS00595
gene id: 1850252:LPB136_RS00595
uniprot id: A0A1L3JFP6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

1850252:LPB136 RS02885
gene id: 1850252:LPB136_RS02885
uniprot id: A0A1L3JH16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1850252:LPB136 RS06860
gene id: 1850252:LPB136_RS06860
uniprot id: A0A1L3JIZ5
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1850252:LPB136 RS02710
gene id: 1850252:LPB136_RS02710
uniprot id: A0A1L3JGV2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1850252:LPB136 RS11515
gene id: 1850252:LPB136_RS11515
uniprot id: A0A1L3JLG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1850252:LPB136 RS07015
gene id: 1850252:LPB136_RS07015
uniprot id: A0A1L3JIY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS11945
gene id: 1850252:LPB136_RS11945
uniprot id: A0A1L3JLJ0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1850252:LPB136 RS02785
gene id: 1850252:LPB136_RS02785
uniprot id: A0A1L3JGW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1850252:LPB136 RS01685
gene id: 1850252:LPB136_RS01685
uniprot id: A0A1L3JGA1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS04800
gene id: 1850252:LPB136_RS04800
uniprot id: A0A1L3JHV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1850252:LPB136 RS11465
gene id: 1850252:LPB136_RS11465
uniprot id: A0A1L3JLG5
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1850252:LPB136 RS06310
gene id: 1850252:LPB136_RS06310
uniprot id: A0A1L3JIR8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1850252:LPB136 RS04550
gene id: 1850252:LPB136_RS04550
uniprot id: A0A1L3JHQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS09555
gene id: 1850252:LPB136_RS09555
uniprot id: A0A1L3JKG0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1850252:LPB136 RS00805
gene id: 1850252:LPB136_RS00805
uniprot id: A0A1L3JFU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1850252:LPB136 RS03850
gene id: 1850252:LPB136_RS03850
uniprot id: A0A1L3JHC2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1850252:LPB136 RS09675
gene id: 1850252:LPB136_RS09675
uniprot id: A0A1L3JKB8
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1850252:LPB136 RS13380
gene id: 1850252:LPB136_RS13380
uniprot id: A0A1L3JMG3
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS04835
gene id: 1850252:LPB136_RS04835
uniprot id: A0A1L3JHV3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1850252:LPB136 RS12435
gene id: 1850252:LPB136_RS12435
uniprot id: A0A1L3JLX0
names: Similarity
messages: Belongs to the peptidase S41A family.

1850252:LPB136 RS07865
gene id: 1850252:LPB136_RS07865
uniprot id: A0A1L3JJE7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1850252:LPB136 RS11235
gene id: 1850252:LPB136_RS11235
uniprot id: A0A1L3JL72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1850252:LPB136 RS03855
gene id: 1850252:LPB136_RS03855
uniprot id: A0A1L3JHC5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS07190
gene id: 1850252:LPB136_RS07190
uniprot id: A0A1L3JJ25
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1850252:LPB136 RS09025
gene id: 1850252:LPB136_RS09025
uniprot id: A0A1L3JK14
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1850252:LPB136 RS07250
gene id: 1850252:LPB136_RS07250
uniprot id: A0A1L3JJ59
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS10260
gene id: 1850252:LPB136_RS10260
uniprot id: A0A1L3JKV4
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS07400
gene id: 1850252:LPB136_RS07400
uniprot id: A0A1L3JJA4
names: Similarity
messages: Belongs to the universal stress protein A family.

1850252:LPB136 RS12360
gene id: 1850252:LPB136_RS12360
uniprot id: A0A1L3JLS3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1850252:LPB136 RS13630
gene id: 1850252:LPB136_RS13630
uniprot id: A0A1L3JMH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1850252:LPB136 RS11390
gene id: 1850252:LPB136_RS11390
uniprot id: A0A1L3JLC5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850252:LPB136 RS13200
gene id: 1850252:LPB136_RS13200
uniprot id: A0A1L3JME2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1850252:LPB136 RS08975
gene id: 1850252:LPB136_RS08975
uniprot id: A0A1L3JK04
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1850252:LPB136 RS12515
gene id: 1850252:LPB136_RS12515
uniprot id: A0A1L3JM11
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850252:LPB136 RS07640
gene id: 1850252:LPB136_RS07640
uniprot id: A0A1L3JJB4
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS06695
gene id: 1850252:LPB136_RS06695
uniprot id: A0A1L3JIT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1850252:LPB136 RS09395
gene id: 1850252:LPB136_RS09395
uniprot id: A0A1L3JKA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

1850252:LPB136 RS02975
gene id: 1850252:LPB136_RS02975
uniprot id: A0A1L3JGY5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1850252:LPB136 RS08515
gene id: 1850252:LPB136_RS08515
uniprot id: A0A1L3JJS2
names: Similarity
messages: Belongs to the DapA family.

1850252:LPB136 RS08005
gene id: 1850252:LPB136_RS08005
uniprot id: A0A1L3JJI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1850252:LPB136 RS10745
gene id: 1850252:LPB136_RS10745
uniprot id: A0A1L3JL43
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1850252:LPB136 RS08345
gene id: 1850252:LPB136_RS08345
uniprot id: A0A1L3JJS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850252:LPB136 RS00825
gene id: 1850252:LPB136_RS00825
uniprot id: A0A1L3JFT5
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1850252:LPB136 RS06020
gene id: 1850252:LPB136_RS06020
uniprot id: A0A1L3JIJ5
names: Similarity
messages: Belongs to the RutC family.

1850252:LPB136 RS10265
gene id: 1850252:LPB136_RS10265
uniprot id: A0A1L3JKP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1850252:LPB136 RS08485
gene id: 1850252:LPB136_RS08485
uniprot id: A0A1L3JJQ8
names: Similarity
messages: Belongs to the peptidase M24B family.

1850252:LPB136 RS01215
gene id: 1850252:LPB136_RS01215
uniprot id: A0A1L3JG09
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850252:LPB136 RS11350
gene id: 1850252:LPB136_RS11350
uniprot id: A0A1L3JLE3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1850252:LPB136 RS01080
gene id: 1850252:LPB136_RS01080
uniprot id: A0A1L3JFX9
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.

1850252:LPB136 RS06515
gene id: 1850252:LPB136_RS06515
uniprot id: A0A1L3JIT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1850252:LPB136 RS00325
gene id: 1850252:LPB136_RS00325
uniprot id: A0A1L3JFJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1850252:LPB136 RS03315
gene id: 1850252:LPB136_RS03315
uniprot id: A0A1L3JH30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1850252:LPB136 RS06700
gene id: 1850252:LPB136_RS06700
uniprot id: A0A1L3JIW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1850252:LPB136 RS13455
gene id: 1850252:LPB136_RS13455
uniprot id: A0A1L3JMD9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1850252:LPB136 RS12310
gene id: 1850252:LPB136_RS12310
uniprot id: A0A1L3JLR3
names: Similarity
messages: Belongs to the UPF0102 family.

1850252:LPB136 RS09710
gene id: 1850252:LPB136_RS09710
uniprot id: A0A1L3JKJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1850252:LPB136 RS06180
gene id: 1850252:LPB136_RS06180
uniprot id: A0A1L3JIQ0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1850252:LPB136 RS02290
gene id: 1850252:LPB136_RS02290
uniprot id: A0A1L3JGK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1850252:LPB136 RS12825
gene id: 1850252:LPB136_RS12825
uniprot id: A0A1L3JM43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1850252:LPB136 RS04065
gene id: 1850252:LPB136_RS04065
uniprot id: A0A1L3JHJ1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1850252:LPB136 RS09990
gene id: 1850252:LPB136_RS09990
uniprot id: A0A1L3JKL6
names: Similarity
messages: Belongs to the universal stress protein A family.

1850252:LPB136 RS02125
gene id: 1850252:LPB136_RS02125
uniprot id: A0A1L3JGN4
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1850252:LPB136 RS03540
gene id: 1850252:LPB136_RS03540
uniprot id: A0A1L3JH76
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850252:LPB136 RS11940
gene id: 1850252:LPB136_RS11940
uniprot id: A0A1L3JLJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS02315
gene id: 1850252:LPB136_RS02315
uniprot id: A0A1L3JGM2
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS07000
gene id: 1850252:LPB136_RS07000
uniprot id: A0A1L3JJ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1850252:LPB136 RS06865
gene id: 1850252:LPB136_RS06865
uniprot id: A0A1L3JIX8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1850252:LPB136 RS11460
gene id: 1850252:LPB136_RS11460
uniprot id: A0A1L3JLF5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS00435
gene id: 1850252:LPB136_RS00435
uniprot id: A0A1L3JFL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS00345
gene id: 1850252:LPB136_RS00345
uniprot id: A0A1L3JFK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1850252:LPB136 RS09405
gene id: 1850252:LPB136_RS09405
uniprot id: A0A1L3JKD4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1850252:LPB136 RS08225
gene id: 1850252:LPB136_RS08225
uniprot id: A0A1L3JJQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1850252:LPB136 RS09965
gene id: 1850252:LPB136_RS09965
uniprot id: A0A1L3JKG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1850252:LPB136 RS03365
gene id: 1850252:LPB136_RS03365
uniprot id: A0A1L3JH73
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1850252:LPB136 RS07705
gene id: 1850252:LPB136_RS07705
uniprot id: A0A1L3JJB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1850252:LPB136 RS06505
gene id: 1850252:LPB136_RS06505
uniprot id: A0A1L3JIV5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1850252:LPB136 RS12695
gene id: 1850252:LPB136_RS12695
uniprot id: A0A1L3JM12
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS12865
gene id: 1850252:LPB136_RS12865
uniprot id: A0A1L3JM86
names: Subcellular Location Annotation
messages: Periplasm

1850252:LPB136 RS08420
gene id: 1850252:LPB136_RS08420
uniprot id: A0A1L3JJT1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1850252:LPB136 RS02135
gene id: 1850252:LPB136_RS02135
uniprot id: A0A1L3JGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1850252:LPB136 RS09170
gene id: 1850252:LPB136_RS09170
uniprot id: A0A1L3JK53
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS03320
gene id: 1850252:LPB136_RS03320
uniprot id: A0A1L3JH52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1850252:LPB136 RS01595
gene id: 1850252:LPB136_RS01595
uniprot id: A0A1L3JGD1
names: Similarity
messages: Belongs to the threonine aldolase family.

1850252:LPB136 RS07305
gene id: 1850252:LPB136_RS07305
uniprot id: A0A1L3JJ72
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1850252:LPB136 RS10725
gene id: 1850252:LPB136_RS10725
uniprot id: A0A1L3JL00
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1850252:LPB136 RS07780
gene id: 1850252:LPB136_RS07780
uniprot id: A0A1L3JJF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS00280
gene id: 1850252:LPB136_RS00280
uniprot id: A0A1L3JFI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1850252:LPB136 RS07760
gene id: 1850252:LPB136_RS07760
uniprot id: A0A1L3JJC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1850252:LPB136 RS09265
gene id: 1850252:LPB136_RS09265
uniprot id: A0A1L3JK48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1850252:LPB136 RS03060
gene id: 1850252:LPB136_RS03060
uniprot id: A0A1L3JH56
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1850252:LPB136 RS02575
gene id: 1850252:LPB136_RS02575
uniprot id: A0A1L3JGS8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1850252:LPB136 RS01505
gene id: 1850252:LPB136_RS01505
uniprot id: A0A1L3JG55
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1850252:LPB136 RS05515
gene id: 1850252:LPB136_RS05515
uniprot id: A0A1L3JIA4
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1850252:LPB136 RS05055
gene id: 1850252:LPB136_RS05055
uniprot id: A0A1L3JI35
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1850252:LPB136 RS03530
gene id: 1850252:LPB136_RS03530
uniprot id: A0A1L3JH66
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS04580
gene id: 1850252:LPB136_RS04580
uniprot id: A0A1L3JHT3
names: Similarity
messages: Belongs to the DEAD box helicase family.

1850252:LPB136 RS03295
gene id: 1850252:LPB136_RS03295
uniprot id: A0A1L3JHA1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1850252:LPB136 RS10250
gene id: 1850252:LPB136_RS10250
uniprot id: A0A1L3JKT3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS01380
gene id: 1850252:LPB136_RS01380
uniprot id: A0A1L3JG52
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1850252:LPB136 RS11915
gene id: 1850252:LPB136_RS11915
uniprot id: A0A1L3JLJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1850252:LPB136 RS00040
gene id: 1850252:LPB136_RS00040
uniprot id: A0A1L3JMG3
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS00360
gene id: 1850252:LPB136_RS00360
uniprot id: A0A1L3JFL9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1850252:LPB136 RS11140
gene id: 1850252:LPB136_RS11140
uniprot id: A0A1L3JL79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1850252:LPB136 RS09610
gene id: 1850252:LPB136_RS09610
uniprot id: A0A1L3JKH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1850252:LPB136 RS06430
gene id: 1850252:LPB136_RS06430
uniprot id: A0A1L3JIS0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1850252:LPB136 RS02775
gene id: 1850252:LPB136_RS02775
uniprot id: A0A1L3JGU4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1850252:LPB136 RS08335
gene id: 1850252:LPB136_RS08335
uniprot id: A0A1L3JJN0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1850252:LPB136 RS04340
gene id: 1850252:LPB136_RS04340
uniprot id: A0A1L3JHL8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1850252:LPB136 RS11040
gene id: 1850252:LPB136_RS11040
uniprot id: A0A1L3JL60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1850252:LPB136 RS07560
gene id: 1850252:LPB136_RS07560
uniprot id: A0A1L3JJC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1850252:LPB136 RS05205
gene id: 1850252:LPB136_RS05205
uniprot id: A0A1L3JI44
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1850252:LPB136 RS12440
gene id: 1850252:LPB136_RS12440
uniprot id: A0A1L3JLZ8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1850252:LPB136 RS01540
gene id: 1850252:LPB136_RS01540
uniprot id: A0A1L3JG80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1850252:LPB136 RS03210
gene id: 1850252:LPB136_RS03210
uniprot id: A0A1L3JH21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1850252:LPB136 RS02720
gene id: 1850252:LPB136_RS02720
uniprot id: A0A1L3JGU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1850252:LPB136 RS02555
gene id: 1850252:LPB136_RS02555
uniprot id: A0A1L3JGR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1850252:LPB136 RS13135
gene id: 1850252:LPB136_RS13135
uniprot id: A0A1L3JM73
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1850252:LPB136 RS10130
gene id: 1850252:LPB136_RS10130
uniprot id: A0A1L3JKN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1850252:LPB136 RS06705
gene id: 1850252:LPB136_RS06705
uniprot id: A0A1L3JIV8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1850252:LPB136 RS04970
gene id: 1850252:LPB136_RS04970
uniprot id: A0A1L3JHX7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1850252:LPB136 RS02825
gene id: 1850252:LPB136_RS02825
uniprot id: A0A1L3JGV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1850252:LPB136 RS13075
gene id: 1850252:LPB136_RS13075
uniprot id: A0A1L3JM80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1850252:LPB136 RS11735
gene id: 1850252:LPB136_RS11735
uniprot id: A0A1L3JLL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1850252:LPB136 RS09620
gene id: 1850252:LPB136_RS09620
uniprot id: A0A1L3JKC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1850252:LPB136 RS09525
gene id: 1850252:LPB136_RS09525
uniprot id: A0A1L3JK88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1850252:LPB136 RS05610
gene id: 1850252:LPB136_RS05610
uniprot id: A0A1L3JI91
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850252:LPB136 RS10895
gene id: 1850252:LPB136_RS10895
uniprot id: A0A1L3JL07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1850252:LPB136 RS03225
gene id: 1850252:LPB136_RS03225
uniprot id: A0A1L3JH20
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1850252:LPB136 RS03775
gene id: 1850252:LPB136_RS03775
uniprot id: A0A1L3JHE3
names: Similarity
messages: Belongs to the peptidase C1 family.

1850252:LPB136 RS11520
gene id: 1850252:LPB136_RS11520
uniprot id: A0A1L3JMW2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1850252:LPB136 RS05160
gene id: 1850252:LPB136_RS05160
uniprot id: A0A1L3JI10
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

1850252:LPB136 RS01700
gene id: 1850252:LPB136_RS01700
uniprot id: A0A1L3JGF0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1850252:LPB136 RS09240
gene id: 1850252:LPB136_RS09240
uniprot id: A0A1L3JK96
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1850252:LPB136 RS04205
gene id: 1850252:LPB136_RS04205
uniprot id: A0A1L3JHM7
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

1850252:LPB136 RS01660
gene id: 1850252:LPB136_RS01660
uniprot id: A0A1L3JG81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1850252:LPB136 RS04040
gene id: 1850252:LPB136_RS04040
uniprot id: A0A1L3JHJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS04085
gene id: 1850252:LPB136_RS04085
uniprot id: A0A1L3JHH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1850252:LPB136 RS00535
gene id: 1850252:LPB136_RS00535
uniprot id: A0A1L3JMM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1850252:LPB136 RS12510
gene id: 1850252:LPB136_RS12510
uniprot id: A0A1L3JLY2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850252:LPB136 RS09470
gene id: 1850252:LPB136_RS09470
uniprot id: A0A1L3JK95
names: Similarity
messages: Belongs to the MoaD family.

1850252:LPB136 RS00160
gene id: 1850252:LPB136_RS00160
uniprot id: A0A1L3JFH0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS00780
gene id: 1850252:LPB136_RS00780
uniprot id: A0A1L3JFS6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1850252:LPB136 RS12770
gene id: 1850252:LPB136_RS12770
uniprot id: A0A1L3JM35
names: Similarity
messages: Belongs to the universal stress protein A family.

1850252:LPB136 RS00505
gene id: 1850252:LPB136_RS00505
uniprot id: A0A1L3JFM7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1850252:LPB136 RS11340
gene id: 1850252:LPB136_RS11340
uniprot id: A0A1L3JLD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1850252:LPB136 RS09975
gene id: 1850252:LPB136_RS09975
uniprot id: A0A1L3JKK5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1850252:LPB136 RS06030
gene id: 1850252:LPB136_RS06030
uniprot id: A0A1L3JIG9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1850252:LPB136 RS11660
gene id: 1850252:LPB136_RS11660
uniprot id: A0A1L3JLJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1850252:LPB136 RS01075
gene id: 1850252:LPB136_RS01075
uniprot id: A0A1L3JG04
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS03010
gene id: 1850252:LPB136_RS03010
uniprot id: A0A1L3JH45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1850252:LPB136 RS11825
gene id: 1850252:LPB136_RS11825
uniprot id: A0A1L3JLM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1850252:LPB136 RS07025
gene id: 1850252:LPB136_RS07025
uniprot id: A0A1L3JJ08
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1850252:LPB136 RS05175
gene id: 1850252:LPB136_RS05175
uniprot id: A0A1L3JI37
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1850252:LPB136 RS03120
gene id: 1850252:LPB136_RS03120
uniprot id: A0A1L3JH71
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1850252:LPB136 RS12355
gene id: 1850252:LPB136_RS12355
uniprot id: A0A1L3JLZ1
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS04630
gene id: 1850252:LPB136_RS04630
uniprot id: A0A1L3JHR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1850252:LPB136 RS07115
gene id: 1850252:LPB136_RS07115
uniprot id: A0A1L3JJ01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS05195
gene id: 1850252:LPB136_RS05195
uniprot id: A0A1L3JI46
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1850252:LPB136 RS06350
gene id: 1850252:LPB136_RS06350
uniprot id: A0A1L3JIM4
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1850252:LPB136 RS07430
gene id: 1850252:LPB136_RS07430
uniprot id: A0A1L3JJ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1850252:LPB136 RS09455
gene id: 1850252:LPB136_RS09455
uniprot id: A0A1L3JKE0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1850252:LPB136 RS04890
gene id: 1850252:LPB136_RS04890
uniprot id: A0A1L3JI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1850252:LPB136 RS00300
gene id: 1850252:LPB136_RS00300
uniprot id: A0A1L3JFJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1850252:LPB136 RS11775
gene id: 1850252:LPB136_RS11775
uniprot id: A0A1L3JLL2
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS03705
gene id: 1850252:LPB136_RS03705
uniprot id: A0A1L3JHA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1850252:LPB136 RS12325
gene id: 1850252:LPB136_RS12325
uniprot id: A0A1L3JLV1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1850252:LPB136 RS10840
gene id: 1850252:LPB136_RS10840
uniprot id: A0A1L3JKZ7
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS04190
gene id: 1850252:LPB136_RS04190
uniprot id: A0A1L3JHJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1850252:LPB136 RS05220
gene id: 1850252:LPB136_RS05220
uniprot id: A0A1L3JI60
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850252:LPB136 RS00945
gene id: 1850252:LPB136_RS00945
uniprot id: A0A1L3JFY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1850252:LPB136 RS09380
gene id: 1850252:LPB136_RS09380
uniprot id: A0A1L3JK99
names: Similarity
messages: Belongs to the SCO1/2 family.

1850252:LPB136 RS02755
gene id: 1850252:LPB136_RS02755
uniprot id: A0A1L3JGZ7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1850252:LPB136 RS01580
gene id: 1850252:LPB136_RS01580
uniprot id: A0A1L3JG82
names: Similarity
messages: Belongs to the ArsC family.

1850252:LPB136 RS00530
gene id: 1850252:LPB136_RS00530
uniprot id: A0A1L3JFN6
names: Similarity
messages: Belongs to the glutamate synthase family.

1850252:LPB136 RS12690
gene id: 1850252:LPB136_RS12690
uniprot id: A0A1L3JLX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1850252:LPB136 RS10945
gene id: 1850252:LPB136_RS10945
uniprot id: A0A1L3JL16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1850252:LPB136 RS01890
gene id: 1850252:LPB136_RS01890
uniprot id: A0A1L3JGE9
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS02385
gene id: 1850252:LPB136_RS02385
uniprot id: A0A1L3JGN6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1850252:LPB136 RS11550
gene id: 1850252:LPB136_RS11550
uniprot id: A0A1L3JLE5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1850252:LPB136 RS06810
gene id: 1850252:LPB136_RS06810
uniprot id: A0A1L3JIW8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1850252:LPB136 RS10470
gene id: 1850252:LPB136_RS10470
uniprot id: A0A1L3JKY0
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS01265
gene id: 1850252:LPB136_RS01265
uniprot id: A0A1L3JG16
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS04750
gene id: 1850252:LPB136_RS04750
uniprot id: A0A1L3JHU1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1850252:LPB136 RS13070
gene id: 1850252:LPB136_RS13070
uniprot id: A0A1L3JM69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS10085
gene id: 1850252:LPB136_RS10085
uniprot id: A0A1L3JKN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1850252:LPB136 RS03835
gene id: 1850252:LPB136_RS03835
uniprot id: A0A1L3JHF5
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1850252:LPB136 RS12640
gene id: 1850252:LPB136_RS12640
uniprot id: A0A1L3JLW9
names: Similarity
messages: Belongs to the asparaginase 1 family.

1850252:LPB136 RS12460
gene id: 1850252:LPB136_RS12460
uniprot id: A0A1L3JM02
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1850252:LPB136 RS01850
gene id: 1850252:LPB136_RS01850
uniprot id: A0A1L3JGD3
names: Similarity
messages: Belongs to the IMPACT family.

1850252:LPB136 RS10305
gene id: 1850252:LPB136_RS10305
uniprot id: A0A1L3JKS1
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1850252:LPB136 RS11050
gene id: 1850252:LPB136_RS11050
uniprot id: A0A1L3JL81
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1850252:LPB136 RS08995
gene id: 1850252:LPB136_RS08995
uniprot id: A0A1L3JK54
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1850252:LPB136 RS05640
gene id: 1850252:LPB136_RS05640
uniprot id: A0A1L3JI94
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS01810
gene id: 1850252:LPB136_RS01810
uniprot id: A0A1L3JGB0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1850252:LPB136 RS04960
gene id: 1850252:LPB136_RS04960
uniprot id: A0A1L3JHZ8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1850252:LPB136 RS13645
gene id: 1850252:LPB136_RS13645
uniprot id: A0A1L3JFF2
names: Similarity
messages: Belongs to the peptidase S8 family.

1850252:LPB136 RS06330
gene id: 1850252:LPB136_RS06330
uniprot id: A0A1L3JIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1850252:LPB136 RS12940
gene id: 1850252:LPB136_RS12940
uniprot id: A0A1L3JM82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1850252:LPB136 RS03130
gene id: 1850252:LPB136_RS03130
uniprot id: A0A1L3JGZ6
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

1850252:LPB136 RS10615
gene id: 1850252:LPB136_RS10615
uniprot id: A0A1L3JKY8
names: Similarity
messages: Belongs to the peptidase M13 family.

1850252:LPB136 RS12365
gene id: 1850252:LPB136_RS12365
uniprot id: A0A1L3JLR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1850252:LPB136 RS05530
gene id: 1850252:LPB136_RS05530
uniprot id: A0A1L3JI77
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS00400
gene id: 1850252:LPB136_RS00400
uniprot id: A0A1L3JFL3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1850252:LPB136 RS02015
gene id: 1850252:LPB136_RS02015
uniprot id: A0A1L3JGG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1850252:LPB136 RS03495
gene id: 1850252:LPB136_RS03495
uniprot id: A0A1L3JH91
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1850252:LPB136 RS06480
gene id: 1850252:LPB136_RS06480
uniprot id: A0A1L3JIT0
names: Similarity
messages: Belongs to the UPF0246 family.

1850252:LPB136 RS06435
gene id: 1850252:LPB136_RS06435
uniprot id: A0A1L3JIQ4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1850252:LPB136 RS02595
gene id: 1850252:LPB136_RS02595
uniprot id: A0A1L3JGW9
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS02215
gene id: 1850252:LPB136_RS02215
uniprot id: A0A1L3JGK5
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1850252:LPB136 RS04825
gene id: 1850252:LPB136_RS04825
uniprot id: A0A1L3JHW8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS09715
gene id: 1850252:LPB136_RS09715
uniprot id: A0A1L3JKK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1850252:LPB136 RS03890
gene id: 1850252:LPB136_RS03890
uniprot id: A0A1L3JHK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1850252:LPB136 RS09350
gene id: 1850252:LPB136_RS09350
uniprot id: A0A1L3JKB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1850252:LPB136 RS00525
gene id: 1850252:LPB136_RS00525
uniprot id: A0A1L3JFN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

1850252:LPB136 RS11685
gene id: 1850252:LPB136_RS11685
uniprot id: A0A1L3JLK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1850252:LPB136 RS01670
gene id: 1850252:LPB136_RS01670
uniprot id: A0A1L3JG85
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS06160
gene id: 1850252:LPB136_RS06160
uniprot id: A0A1L3JIL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1850252:LPB136 RS09585
gene id: 1850252:LPB136_RS09585
uniprot id: A0A1L3JKD8
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS04245
gene id: 1850252:LPB136_RS04245
uniprot id: A0A1L3JHM4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1850252:LPB136 RS02100
gene id: 1850252:LPB136_RS02100
uniprot id: A0A1L3JGI2
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS04080
gene id: 1850252:LPB136_RS04080
uniprot id: A0A1L3JHH3
names: Similarity
messages: Belongs to the universal stress protein A family.

1850252:LPB136 RS09165
gene id: 1850252:LPB136_RS09165
uniprot id: A0A1L3JK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1850252:LPB136 RS07425
gene id: 1850252:LPB136_RS07425
uniprot id: A0A1L3JMS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1850252:LPB136 RS08900
gene id: 1850252:LPB136_RS08900
uniprot id: A0A1L3JK22
names: Similarity
messages: Belongs to the Skp family.

1850252:LPB136 RS06375
gene id: 1850252:LPB136_RS06375
uniprot id: A0A1L3JIM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1850252:LPB136 RS00340
gene id: 1850252:LPB136_RS00340
uniprot id: A0A1L3JFK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1850252:LPB136 RS06975
gene id: 1850252:LPB136_RS06975
uniprot id: A0A1L3JIZ7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1850252:LPB136 RS04250
gene id: 1850252:LPB136_RS04250
uniprot id: A0A1L3JHK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1850252:LPB136 RS07175
gene id: 1850252:LPB136_RS07175
uniprot id: A0A1L3JJ56
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1850252:LPB136 RS13370
gene id: 1850252:LPB136_RS13370
uniprot id: A0A1L3JFE2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850252:LPB136 RS07785
gene id: 1850252:LPB136_RS07785
uniprot id: A0A1L3JJC0
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS02890
gene id: 1850252:LPB136_RS02890
uniprot id: A0A1L3JGY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1850252:LPB136 RS11780
gene id: 1850252:LPB136_RS11780
uniprot id: A0A1L3JLM6
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS01875
gene id: 1850252:LPB136_RS01875
uniprot id: A0A1L3JGC9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1850252:LPB136 RS08415
gene id: 1850252:LPB136_RS08415
uniprot id: A0A1L3JJQ4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1850252:LPB136 RS07625
gene id: 1850252:LPB136_RS07625
uniprot id: A0A1L3JJ93
names: Similarity
messages: Belongs to the MreC family.

1850252:LPB136 RS00225
gene id: 1850252:LPB136_RS00225
uniprot id: A0A1L3JFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS01935
gene id: 1850252:LPB136_RS01935
uniprot id: A0A1L3JGE8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1850252:LPB136 RS00350
gene id: 1850252:LPB136_RS00350
uniprot id: A0A1L3JFK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1850252:LPB136 RS06055
gene id: 1850252:LPB136_RS06055
uniprot id: A0A1L3JIH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1850252:LPB136 RS12415
gene id: 1850252:LPB136_RS12415
uniprot id: A0A1L3JLZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS12895
gene id: 1850252:LPB136_RS12895
uniprot id: A0A1L3JM96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS11035
gene id: 1850252:LPB136_RS11035
uniprot id: A0A1L3JL18
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS02065
gene id: 1850252:LPB136_RS02065
uniprot id: A0A1L3JGH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1850252:LPB136 RS04020
gene id: 1850252:LPB136_RS04020
uniprot id: A0A1L3JHH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1850252:LPB136 RS07200
gene id: 1850252:LPB136_RS07200
uniprot id: A0A1L3JJ69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1850252:LPB136 RS04590
gene id: 1850252:LPB136_RS04590
uniprot id: A0A1L3JHT0
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1850252:LPB136 RS01015
gene id: 1850252:LPB136_RS01015
uniprot id: A0A1L3JG35
names: Similarity
messages: Belongs to the ParB family.

1850252:LPB136 RS09325
gene id: 1850252:LPB136_RS09325
uniprot id: A0A1L3JK89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS00290
gene id: 1850252:LPB136_RS00290
uniprot id: A0A1L3JFJ8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1850252:LPB136 RS08080
gene id: 1850252:LPB136_RS08080
uniprot id: A0A1L3JJN1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1850252:LPB136 RS02170
gene id: 1850252:LPB136_RS02170
uniprot id: A0A1L3JGI3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850252:LPB136 RS11070
gene id: 1850252:LPB136_RS11070
uniprot id: A0A1L3JL91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1850252:LPB136 RS07620
gene id: 1850252:LPB136_RS07620
uniprot id: A0A1L3JJC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS05410
gene id: 1850252:LPB136_RS05410
uniprot id: A0A1L3JI57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS05355
gene id: 1850252:LPB136_RS05355
uniprot id: A0A1L3JI76
names: Similarity
messages: Belongs to the BshC family.

1850252:LPB136 RS03955
gene id: 1850252:LPB136_RS03955
uniprot id: A0A1L3JHE8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS08830
gene id: 1850252:LPB136_RS08830
uniprot id: A0A1L3JK18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

1850252:LPB136 RS12625
gene id: 1850252:LPB136_RS12625
uniprot id: A0A1L3JM26
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1850252:LPB136 RS07605
gene id: 1850252:LPB136_RS07605
uniprot id: A0A1L3JJ92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS08965
gene id: 1850252:LPB136_RS08965
uniprot id: A0A1L3JK02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1850252:LPB136 RS08360
gene id: 1850252:LPB136_RS08360
uniprot id: A0A1L3JJM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1850252:LPB136 RS03790
gene id: 1850252:LPB136_RS03790
uniprot id: A0A1L3JHB3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850252:LPB136 RS12140
gene id: 1850252:LPB136_RS12140
uniprot id: A0A1L3JLU9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS05930
gene id: 1850252:LPB136_RS05930
uniprot id: A0A1L3JIF6
names: Similarity
messages: Belongs to the malate synthase family.

1850252:LPB136 RS00235
gene id: 1850252:LPB136_RS00235
uniprot id: A0A1L3JFK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS13610
gene id: 1850252:LPB136_RS13610
uniprot id: A0A1L3JFF3
names: Subunit
messages: Monomer.

1850252:LPB136 RS06385
gene id: 1850252:LPB136_RS06385
uniprot id: A0A1L3JIP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850252:LPB136 RS09850
gene id: 1850252:LPB136_RS09850
uniprot id: A0A1L3JKI5
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1850252:LPB136 RS03860
gene id: 1850252:LPB136_RS03860
uniprot id: A0A1L3JHF2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1850252:LPB136 RS08875
gene id: 1850252:LPB136_RS08875
uniprot id: A0A1L3JK34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS10245
gene id: 1850252:LPB136_RS10245
uniprot id: A0A1L3JKR2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS02030
gene id: 1850252:LPB136_RS02030
uniprot id: A0A1L3JGF7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1850252:LPB136 RS04100
gene id: 1850252:LPB136_RS04100
uniprot id: A0A1L3JHK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1850252:LPB136 RS10605
gene id: 1850252:LPB136_RS10605
uniprot id: A0A1L3JKY7
names: Similarity
messages: Belongs to the peptidase S9A family.

1850252:LPB136 RS06715
gene id: 1850252:LPB136_RS06715
uniprot id: A0A1L3JIU0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1850252:LPB136 RS05980
gene id: 1850252:LPB136_RS05980
uniprot id: A0A1L3JIH5
names: Similarity
messages: Belongs to the AHA1 family.

1850252:LPB136 RS12575
gene id: 1850252:LPB136_RS12575
uniprot id: A0A1L3JM16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

1850252:LPB136 RS13005
gene id: 1850252:LPB136_RS13005
uniprot id: A0A1L3JMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1850252:LPB136 RS03980
gene id: 1850252:LPB136_RS03980
uniprot id: A0A1L3JHF6
names: Similarity
messages: Belongs to the MQO family.

1850252:LPB136 RS11560
gene id: 1850252:LPB136_RS11560
uniprot id: A0A1L3JLC6
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS12830
gene id: 1850252:LPB136_RS12830
uniprot id: A0A1L3JM77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1850252:LPB136 RS03430
gene id: 1850252:LPB136_RS03430
uniprot id: A0A1L3JH68
names: Similarity
messages: Belongs to the peptidase M1 family.

1850252:LPB136 RS08000
gene id: 1850252:LPB136_RS08000
uniprot id: A0A1L3JJK3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS01095
gene id: 1850252:LPB136_RS01095
uniprot id: A0A1L3JFZ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1850252:LPB136 RS03255
gene id: 1850252:LPB136_RS03255
uniprot id: A0A1L3JMM1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS12785
gene id: 1850252:LPB136_RS12785
uniprot id: A0A1L3JM76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1850252:LPB136 RS04455
gene id: 1850252:LPB136_RS04455
uniprot id: A0A1L3JHP0
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1850252:LPB136 RS06370
gene id: 1850252:LPB136_RS06370
uniprot id: A0A1L3JIM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1850252:LPB136 RS05680
gene id: 1850252:LPB136_RS05680
uniprot id: A0A1L3JIE8
names: Similarity
messages: Belongs to the peptidase S8 family.

1850252:LPB136 RS08095
gene id: 1850252:LPB136_RS08095
uniprot id: A0A1L3JJH5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1850252:LPB136 RS09190
gene id: 1850252:LPB136_RS09190
uniprot id: A0A1L3JK86
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1850252:LPB136 RS09560
gene id: 1850252:LPB136_RS09560
uniprot id: A0A1L3JKG6
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1850252:LPB136 RS06660
gene id: 1850252:LPB136_RS06660
uniprot id: A0A1L3JIT7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1850252:LPB136 RS02115
gene id: 1850252:LPB136_RS02115
uniprot id: A0A1L3JGH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1850252:LPB136 RS01180
gene id: 1850252:LPB136_RS01180
uniprot id: A0A1L3JG06
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1850252:LPB136 RS04495
gene id: 1850252:LPB136_RS04495
uniprot id: A0A1L3JHP5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1850252:LPB136 RS01565
gene id: 1850252:LPB136_RS01565
uniprot id: A0A1L3JG66
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1850252:LPB136 RS02675
gene id: 1850252:LPB136_RS02675
uniprot id: A0A1L3JGS9
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS02195
gene id: 1850252:LPB136_RS02195
uniprot id: A0A1L3JGJ5
names: Similarity
messages: Belongs to the Skp family.

1850252:LPB136 RS12915
gene id: 1850252:LPB136_RS12915
uniprot id: A0A1L3JM54
names: Similarity
messages: Belongs to the UPF0045 family.

1850252:LPB136 RS09450
gene id: 1850252:LPB136_RS09450
uniprot id: A0A1L3JKB7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1850252:LPB136 RS06155
gene id: 1850252:LPB136_RS06155
uniprot id: A0A1L3JIL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1850252:LPB136 RS00480
gene id: 1850252:LPB136_RS00480
uniprot id: A0A1L3JFN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS02020
gene id: 1850252:LPB136_RS02020
uniprot id: A0A1L3JGL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1850252:LPB136 RS06490
gene id: 1850252:LPB136_RS06490
uniprot id: A0A1L3JIS9
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS00370
gene id: 1850252:LPB136_RS00370
uniprot id: A0A1L3JFL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1850252:LPB136 RS12040
gene id: 1850252:LPB136_RS12040
uniprot id: A0A1L3JLS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1850252:LPB136 RS11065
gene id: 1850252:LPB136_RS11065
uniprot id: A0A1L3JL80
names: Similarity
messages: Belongs to the peptidase S41A family.

1850252:LPB136 RS11175
gene id: 1850252:LPB136_RS11175
uniprot id: A0A1L3JLB2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1850252:LPB136 RS07350
gene id: 1850252:LPB136_RS07350
uniprot id: A0A1L3JJ80
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS13035
gene id: 1850252:LPB136_RS13035
uniprot id: A0A1L3JM50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1850252:LPB136 RS02325
gene id: 1850252:LPB136_RS02325
uniprot id: A0A1L3JGM4
names: Similarity
messages: Belongs to the CinA family.

1850252:LPB136 RS00800
gene id: 1850252:LPB136_RS00800
uniprot id: A0A1L3JFS7
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS02245
gene id: 1850252:LPB136_RS02245
uniprot id: A0A1L3JGK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS10225
gene id: 1850252:LPB136_RS10225
uniprot id: A0A1L3JKQ9
names: Similarity
messages: Belongs to the aspartokinase family.

1850252:LPB136 RS05825
gene id: 1850252:LPB136_RS05825
uniprot id: A0A1L3JID5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1850252:LPB136 RS07775
gene id: 1850252:LPB136_RS07775
uniprot id: A0A1L3JJH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1850252:LPB136 RS12680
gene id: 1850252:LPB136_RS12680
uniprot id: A0A1L3JM47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1850252:LPB136 RS03200
gene id: 1850252:LPB136_RS03200
uniprot id: A0A1L3JH33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS12120
gene id: 1850252:LPB136_RS12120
uniprot id: A0A1L3JLU0
names: Similarity
messages: Belongs to the peptidase S24 family.

1850252:LPB136 RS04145
gene id: 1850252:LPB136_RS04145
uniprot id: A0A1L3JHQ3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1850252:LPB136 RS07855
gene id: 1850252:LPB136_RS07855
uniprot id: A0A1L3JJH7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1850252:LPB136 RS09045
gene id: 1850252:LPB136_RS09045
uniprot id: A0A1L3JK72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1850252:LPB136 RS06290
gene id: 1850252:LPB136_RS06290
uniprot id: A0A1L3JIN5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1850252:LPB136 RS06380
gene id: 1850252:LPB136_RS06380
uniprot id: A0A1L3JIR0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1850252:LPB136 RS10810
gene id: 1850252:LPB136_RS10810
uniprot id: A0A1L3JL55
names: Similarity
messages: Belongs to the UPF0145 family.

1850252:LPB136 RS09440
gene id: 1850252:LPB136_RS09440
uniprot id: A0A1L3JK79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1850252:LPB136 RS02330
gene id: 1850252:LPB136_RS02330
uniprot id: A0A1L3JGS2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1850252:LPB136 RS10760
gene id: 1850252:LPB136_RS10760
uniprot id: A0A1L3JMU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1850252:LPB136 RS06630
gene id: 1850252:LPB136_RS06630
uniprot id: A0A1L3JIS4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1850252:LPB136 RS06295
gene id: 1850252:LPB136_RS06295
uniprot id: A0A1L3JIL1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1850252:LPB136 RS06345
gene id: 1850252:LPB136_RS06345
uniprot id: A0A1L3JIM7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1850252:LPB136 RS00255
gene id: 1850252:LPB136_RS00255
uniprot id: A0A1L3JFQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1850252:LPB136 RS09900
gene id: 1850252:LPB136_RS09900
uniprot id: A0A1L3JKK2
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS05495
gene id: 1850252:LPB136_RS05495
uniprot id: A0A1L3JI70
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1850252:LPB136 RS04220
gene id: 1850252:LPB136_RS04220
uniprot id: A0A1L3JHM9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1850252:LPB136 RS13130
gene id: 1850252:LPB136_RS13130
uniprot id: A0A1L3JMD7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1850252:LPB136 RS06535
gene id: 1850252:LPB136_RS06535
uniprot id: A0A1L3JIS6
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1850252:LPB136 RS05625
gene id: 1850252:LPB136_RS05625
uniprot id: A0A1L3JIF5
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1850252:LPB136 RS08455
gene id: 1850252:LPB136_RS08455
uniprot id: A0A1L3JJT4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1850252:LPB136 RS09565
gene id: 1850252:LPB136_RS09565
uniprot id: A0A1L3JKH3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1850252:LPB136 RS05615
gene id: 1850252:LPB136_RS05615
uniprot id: A0A1L3JI93
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1850252:LPB136 RS00250
gene id: 1850252:LPB136_RS00250
uniprot id: A0A1L3JFI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1850252:LPB136 RS04840
gene id: 1850252:LPB136_RS04840
uniprot id: A0A1L3JHY8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1850252:LPB136 RS01130
gene id: 1850252:LPB136_RS01130
uniprot id: A0A1L3JG02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1850252:LPB136 RS02700
gene id: 1850252:LPB136_RS02700
uniprot id: A0A1L3JGU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1850252:LPB136 RS11500
gene id: 1850252:LPB136_RS11500
uniprot id: A0A1L3JLG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1850252:LPB136 RS06500
gene id: 1850252:LPB136_RS06500
uniprot id: A0A1L3JIQ7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1850252:LPB136 RS05050
gene id: 1850252:LPB136_RS05050
uniprot id: A0A1L3JHZ5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1850252:LPB136 RS00305
gene id: 1850252:LPB136_RS00305
uniprot id: A0A1L3JFR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1850252:LPB136 RS00775
gene id: 1850252:LPB136_RS00775
uniprot id: A0A1L3JFS9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1850252:LPB136 RS05345
gene id: 1850252:LPB136_RS05345
uniprot id: A0A1L3JI52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1850252:LPB136 RS01535
gene id: 1850252:LPB136_RS01535
uniprot id: A0A1L3JGC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1850252:LPB136 RS10495
gene id: 1850252:LPB136_RS10495
uniprot id: A0A1L3JKU9
names: Similarity
messages: Belongs to the SufE family.

1850252:LPB136 RS00420
gene id: 1850252:LPB136_RS00420
uniprot id: A0A1L3JFL2
names: Similarity
messages: Belongs to the citrate synthase family.

1850252:LPB136 RS12580
gene id: 1850252:LPB136_RS12580
uniprot id: A0A1L3JM28
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1850252:LPB136 RS02570
gene id: 1850252:LPB136_RS02570
uniprot id: A0A1L3JGP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1850252:LPB136 RS10210
gene id: 1850252:LPB136_RS10210
uniprot id: A0A1L3JKU5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1850252:LPB136 RS01555
gene id: 1850252:LPB136_RS01555
uniprot id: A0A1L3JMQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS00745
gene id: 1850252:LPB136_RS00745
uniprot id: A0A1L3JFT0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1850252:LPB136 RS02200
gene id: 1850252:LPB136_RS02200
uniprot id: A0A1L3JGI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS09065
gene id: 1850252:LPB136_RS09065
uniprot id: A0A1L3JK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1850252:LPB136 RS04075
gene id: 1850252:LPB136_RS04075
uniprot id: A0A1L3JHJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1850252:LPB136 RS04910
gene id: 1850252:LPB136_RS04910
uniprot id: A0A1L3JHX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1850252:LPB136 RS07885
gene id: 1850252:LPB136_RS07885
uniprot id: A0A1L3JJD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1850252:LPB136 RS01100
gene id: 1850252:LPB136_RS01100
uniprot id: A0A1L3JG10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1850252:LPB136 RS00650
gene id: 1850252:LPB136_RS00650
uniprot id: A0A1L3JFT4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS05730
gene id: 1850252:LPB136_RS05730
uniprot id: A0A1L3JIB5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1850252:LPB136 RS12275
gene id: 1850252:LPB136_RS12275
uniprot id: A0A1L3JLT6
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Belongs to the GPAT/DAPAT family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1850252:LPB136 RS13385
gene id: 1850252:LPB136_RS13385
uniprot id: A0A1L3JMI4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1850252:LPB136 RS10790
gene id: 1850252:LPB136_RS10790
uniprot id: A0A1L3JKY3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1850252:LPB136 RS00310
gene id: 1850252:LPB136_RS00310
uniprot id: A0A1L3JFK9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1850252:LPB136 RS07295
gene id: 1850252:LPB136_RS07295
uniprot id: A0A1L3JJ73
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1850252:LPB136 RS02120
gene id: 1850252:LPB136_RS02120
uniprot id: A0A1L3JGI4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1850252:LPB136 RS10240
gene id: 1850252:LPB136_RS10240
uniprot id: A0A1L3JKM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1850252:LPB136 RS13450
gene id: 1850252:LPB136_RS13450
uniprot id: A0A1L3JMB9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1850252:LPB136 RS06355
gene id: 1850252:LPB136_RS06355
uniprot id: A0A1L3JIS1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1850252:LPB136 RS07880
gene id: 1850252:LPB136_RS07880
uniprot id: A0A1L3JJH8
names: Similarity
messages: Belongs to the fabD family.

1850252:LPB136 RS04560
gene id: 1850252:LPB136_RS04560
uniprot id: A0A1L3JHX5
names: Similarity
messages: Belongs to the Dps family.

1850252:LPB136 RS11855
gene id: 1850252:LPB136_RS11855
uniprot id: A0A1L3JLK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1850252:LPB136 RS04615
gene id: 1850252:LPB136_RS04615
uniprot id: A0A1L3JHY4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1850252:LPB136 RS09820
gene id: 1850252:LPB136_RS09820
uniprot id: A0A1L3JKL7
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1850252:LPB136 RS12835
gene id: 1850252:LPB136_RS12835
uniprot id: A0A1L3JM67
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1850252:LPB136 RS08820
gene id: 1850252:LPB136_RS08820
uniprot id: A0A1L3JK17
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS05950
gene id: 1850252:LPB136_RS05950
uniprot id: A0A1L3JIL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1850252:LPB136 RS10595
gene id: 1850252:LPB136_RS10595
uniprot id: A0A1L3JKU3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS12270
gene id: 1850252:LPB136_RS12270
uniprot id: A0A1L3JLS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1850252:LPB136 RS04885
gene id: 1850252:LPB136_RS04885
uniprot id: A0A1L3JHW4
names: Similarity
messages: Belongs to the Dps family.

1850252:LPB136 RS10095
gene id: 1850252:LPB136_RS10095
uniprot id: A0A1L3JKN4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS06045
gene id: 1850252:LPB136_RS06045
uniprot id: A0A1L3JIJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850252:LPB136 RS05765
gene id: 1850252:LPB136_RS05765
uniprot id: A0A1L3JID7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1850252:LPB136 RS11255
gene id: 1850252:LPB136_RS11255
uniprot id: A0A1L3JN13
names: Similarity
messages: Belongs to the DEAD box helicase family.

1850252:LPB136 RS01495
gene id: 1850252:LPB136_RS01495
uniprot id: A0A1L3JG69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS09880
gene id: 1850252:LPB136_RS09880
uniprot id: A0A1L3JKM5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1850252:LPB136 RS10940
gene id: 1850252:LPB136_RS10940
uniprot id: A0A1L3JL65
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1850252:LPB136 RS03970
gene id: 1850252:LPB136_RS03970
uniprot id: A0A1L3JHH9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1850252:LPB136 RS08185
gene id: 1850252:LPB136_RS08185
uniprot id: A0A1L3JJQ5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1850252:LPB136 RS00315
gene id: 1850252:LPB136_RS00315
uniprot id: A0A1L3JFJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1850252:LPB136 RS04955
gene id: 1850252:LPB136_RS04955
uniprot id: A0A1L3JI43
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS02730
gene id: 1850252:LPB136_RS02730
uniprot id: A0A1L3JGS6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1850252:LPB136 RS01465
gene id: 1850252:LPB136_RS01465
uniprot id: A0A1L3JG49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1850252:LPB136 RS10190
gene id: 1850252:LPB136_RS10190
uniprot id: A0A1L3JKL9
names: Similarity
messages: Belongs to the ArsC family.

1850252:LPB136 RS06150
gene id: 1850252:LPB136_RS06150
uniprot id: A0A1L3JIL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1850252:LPB136 RS06050
gene id: 1850252:LPB136_RS06050
uniprot id: A0A1L3JIH7
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS07645
gene id: 1850252:LPB136_RS07645
uniprot id: A0A1L3JJD7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1850252:LPB136 RS07820
gene id: 1850252:LPB136_RS07820
uniprot id: A0A1L3JJI3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1850252:LPB136 RS12775
gene id: 1850252:LPB136_RS12775
uniprot id: A0A1L3JM60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1850252:LPB136 RS11385
gene id: 1850252:LPB136_RS11385
uniprot id: A0A1L3JL93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1850252:LPB136 RS03665
gene id: 1850252:LPB136_RS03665
uniprot id: A0A1L3JHC4
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1850252:LPB136 RS07695
gene id: 1850252:LPB136_RS07695
uniprot id: A0A1L3JJC1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850252:LPB136 RS08865
gene id: 1850252:LPB136_RS08865
uniprot id: A0A1L3JJZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS01420
gene id: 1850252:LPB136_RS01420
uniprot id: A0A1L3JG65
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1850252:LPB136 RS00270
gene id: 1850252:LPB136_RS00270
uniprot id: A0A1L3JFJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1850252:LPB136 RS01765
gene id: 1850252:LPB136_RS01765
uniprot id: A0A1L3JGB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1850252:LPB136 RS08265
gene id: 1850252:LPB136_RS08265
uniprot id: A0A1L3JJQ0
names: Similarity
messages: Belongs to the peptidase S41A family.

1850252:LPB136 RS13050
gene id: 1850252:LPB136_RS13050
uniprot id: A0A1L3JMA5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1850252:LPB136 RS01280
gene id: 1850252:LPB136_RS01280
uniprot id: A0A1L3JG31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1850252:LPB136 RS09630
gene id: 1850252:LPB136_RS09630
uniprot id: A0A1L3JKF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1850252:LPB136 RS12985
gene id: 1850252:LPB136_RS12985
uniprot id: A0A1L3JM40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS07320
gene id: 1850252:LPB136_RS07320
uniprot id: A0A1L3JJ88
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS00205
gene id: 1850252:LPB136_RS00205
uniprot id: A0A1L3JFP4
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS02480
gene id: 1850252:LPB136_RS02480
uniprot id: A0A1L3JGP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1850252:LPB136 RS12845
gene id: 1850252:LPB136_RS12845
uniprot id: A0A1L3JM19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1850252:LPB136 RS04160
gene id: 1850252:LPB136_RS04160
uniprot id: A0A1L3JHI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850252:LPB136 RS05505
gene id: 1850252:LPB136_RS05505
uniprot id: A0A1L3JIB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1850252:LPB136 RS08145
gene id: 1850252:LPB136_RS08145
uniprot id: A0A1L3JJI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1850252:LPB136 RS06195
gene id: 1850252:LPB136_RS06195
uniprot id: A0A1L3JIJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1850252:LPB136 RS06255
gene id: 1850252:LPB136_RS06255
uniprot id: A0A1L3JIQ6
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS07060
gene id: 1850252:LPB136_RS07060
uniprot id: A0A1L3JIZ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS07275
gene id: 1850252:LPB136_RS07275
uniprot id: A0A1L3JJ60
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1850252:LPB136 RS01000
gene id: 1850252:LPB136_RS01000
uniprot id: A0A1L3JFX7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1850252:LPB136 RS04055
gene id: 1850252:LPB136_RS04055
uniprot id: A0A1L3JHG5
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1850252:LPB136 RS11145
gene id: 1850252:LPB136_RS11145
uniprot id: A0A1L3JL76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1850252:LPB136 RS13320
gene id: 1850252:LPB136_RS13320
uniprot id: A0A1L3JMG6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1850252:LPB136 RS03985
gene id: 1850252:LPB136_RS03985
uniprot id: A0A1L3JHJ0
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS03765
gene id: 1850252:LPB136_RS03765
uniprot id: A0A1L3JML5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1850252:LPB136 RS06790
gene id: 1850252:LPB136_RS06790
uniprot id: A0A1L3JIX3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1850252:LPB136 RS03600
gene id: 1850252:LPB136_RS03600
uniprot id: A0A1L3JH88
names: Similarity
messages: Belongs to the nitroreductase family.

1850252:LPB136 RS07235
gene id: 1850252:LPB136_RS07235
uniprot id: A0A1L3JJ27
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1850252:LPB136 RS11010
gene id: 1850252:LPB136_RS11010
uniprot id: A0A1L3JL48
names: Similarity
messages: Belongs to the GARS family.

1850252:LPB136 RS10390
gene id: 1850252:LPB136_RS10390
uniprot id: A0A1L3JKS9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1850252:LPB136 RS09280
gene id: 1850252:LPB136_RS09280
uniprot id: A0A1L3JK90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1850252:LPB136 RS00295
gene id: 1850252:LPB136_RS00295
uniprot id: A0A1L3JFJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1850252:LPB136 RS06550
gene id: 1850252:LPB136_RS06550
uniprot id: A0A1L3JIR5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1850252:LPB136 RS02600
gene id: 1850252:LPB136_RS02600
uniprot id: A0A1L3JGS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1850252:LPB136 RS01170
gene id: 1850252:LPB136_RS01170
uniprot id: A0A1L3JMP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1850252:LPB136 RS11210
gene id: 1850252:LPB136_RS11210
uniprot id: A0A1L3JL57
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1850252:LPB136 RS01690
gene id: 1850252:LPB136_RS01690
uniprot id: A0A1L3JG92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1850252:LPB136 RS07735
gene id: 1850252:LPB136_RS07735
uniprot id: A0A1L3JJA9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850252:LPB136 RS03950
gene id: 1850252:LPB136_RS03950
uniprot id: A0A1L3JHE5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1850252:LPB136 RS01085
gene id: 1850252:LPB136_RS01085
uniprot id: A0A1L3JFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS12715
gene id: 1850252:LPB136_RS12715
uniprot id: A0A1L3JM25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1850252:LPB136 RS00405
gene id: 1850252:LPB136_RS00405
uniprot id: A0A1L3JFL7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1850252:LPB136 RS06625
gene id: 1850252:LPB136_RS06625
uniprot id: A0A1L3JIS8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1850252:LPB136 RS03285
gene id: 1850252:LPB136_RS03285
uniprot id: A0A1L3JH28
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1850252:LPB136 RS03345
gene id: 1850252:LPB136_RS03345
uniprot id: A0A1L3JH41
names: Similarity
messages: Belongs to the peptidase M16 family.

1850252:LPB136 RS09000
gene id: 1850252:LPB136_RS09000
uniprot id: A0A1L3JJX8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1850252:LPB136 RS09855
gene id: 1850252:LPB136_RS09855
uniprot id: A0A1L3JKJ1
names: Similarity
messages: Belongs to the peptidase M1 family.

1850252:LPB136 RS00440
gene id: 1850252:LPB136_RS00440
uniprot id: A0A1L3JFN9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850252:LPB136 RS04450
gene id: 1850252:LPB136_RS04450
uniprot id: A0A1L3JHR9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1850252:LPB136 RS03930
gene id: 1850252:LPB136_RS03930
uniprot id: A0A1L3JHE7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1850252:LPB136 RS04345
gene id: 1850252:LPB136_RS04345
uniprot id: A0A1L3JHP1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1850252:LPB136 RS01030
gene id: 1850252:LPB136_RS01030
uniprot id: A0A1L3JFY2
names: Similarity
messages: Belongs to the nitroreductase family.

1850252:LPB136 RS12740
gene id: 1850252:LPB136_RS12740
uniprot id: A0A1L3JLY7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1850252:LPB136 RS03960
gene id: 1850252:LPB136_RS03960
uniprot id: A0A1L3JHH2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1850252:LPB136 RS11875
gene id: 1850252:LPB136_RS11875
uniprot id: A0A1L3JLN8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850252:LPB136 RS11165
gene id: 1850252:LPB136_RS11165
uniprot id: A0A1L3JLA6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1850252:LPB136 RS12900
gene id: 1850252:LPB136_RS12900
uniprot id: A0A1L3JM33
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1850252:LPB136 RS09125
gene id: 1850252:LPB136_RS09125
uniprot id: A0A1L3JK64
names: Similarity
messages: Belongs to the CIA30 family.

1850252:LPB136 RS09085
gene id: 1850252:LPB136_RS09085
uniprot id: A0A1L3JK35
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1850252:LPB136 RS06655
gene id: 1850252:LPB136_RS06655
uniprot id: A0A1L3JIT3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1850252:LPB136 RS10695
gene id: 1850252:LPB136_RS10695
uniprot id: A0A1L3JKX5
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1850252:LPB136 RS06185
gene id: 1850252:LPB136_RS06185
uniprot id: A0A1L3JIM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1850252:LPB136 RS08885
gene id: 1850252:LPB136_RS08885
uniprot id: A0A1L3JJW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1850252:LPB136 RS05925
gene id: 1850252:LPB136_RS05925
uniprot id: A0A1L3JIH2
names: Cofactor
messages: Can also use Mn(2+) ion.

1850252:LPB136 RS11990
gene id: 1850252:LPB136_RS11990
uniprot id: A0A1L3JLR9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1850252:LPB136 RS00660
gene id: 1850252:LPB136_RS00660
uniprot id: A0A1L3JFS0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1850252:LPB136 RS05710
gene id: 1850252:LPB136_RS05710
uniprot id: A0A1L3JIC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1850252:LPB136 RS11160
gene id: 1850252:LPB136_RS11160
uniprot id: A0A1L3JL84
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1850252:LPB136 RS01115
gene id: 1850252:LPB136_RS01115
uniprot id: A0A1L3JFZ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS00285
gene id: 1850252:LPB136_RS00285
uniprot id: A0A1L3JFL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1850252:LPB136 RS06570
gene id: 1850252:LPB136_RS06570
uniprot id: A0A1L3JIU4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1850252:LPB136 RS02985
gene id: 1850252:LPB136_RS02985
uniprot id: A0A1L3JH03
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS05200
gene id: 1850252:LPB136_RS05200
uniprot id: A0A1L3JI39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1850252:LPB136 RS13340
gene id: 1850252:LPB136_RS13340
uniprot id: A0A1L3JM99
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1850252:LPB136 RS13220
gene id: 1850252:LPB136_RS13220
uniprot id: A0A1L3JM88
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1850252:LPB136 RS12055
gene id: 1850252:LPB136_RS12055
uniprot id: A0A1L3JLL0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1850252:LPB136 RS07570
gene id: 1850252:LPB136_RS07570
uniprot id: A0A1L3JJB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1850252:LPB136 RS10535
gene id: 1850252:LPB136_RS10535
uniprot id: A0A1L3JKU4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1850252:LPB136 RS11830
gene id: 1850252:LPB136_RS11830
uniprot id: A0A1L3JLN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1850252:LPB136 RS04530
gene id: 1850252:LPB136_RS04530
uniprot id: A0A1L3JHS4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1850252:LPB136 RS12645
gene id: 1850252:LPB136_RS12645
uniprot id: A0A1L3JM03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1850252:LPB136 RS01375
gene id: 1850252:LPB136_RS01375
uniprot id: A0A1L3JG32
names: Similarity
messages: Belongs to the peptidase C40 family.

1850252:LPB136 RS10155
gene id: 1850252:LPB136_RS10155
uniprot id: A0A1L3JKS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1850252:LPB136 RS10930
gene id: 1850252:LPB136_RS10930
uniprot id: A0A1L3JL40
names: Similarity
messages: Belongs to the DprA/Smf family.

1850252:LPB136 RS00555
gene id: 1850252:LPB136_RS00555
uniprot id: A0A1L3JFQ2
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

1850252:LPB136 RS05755
gene id: 1850252:LPB136_RS05755
uniprot id: A0A1L3JIB3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1850252:LPB136 RS02420
gene id: 1850252:LPB136_RS02420
uniprot id: A0A1L3JGN5
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS08825
gene id: 1850252:LPB136_RS08825
uniprot id: A0A1L3JK31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1850252:LPB136 RS10270
gene id: 1850252:LPB136_RS10270
uniprot id: A0A1L3JKN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS11150
gene id: 1850252:LPB136_RS11150
uniprot id: A0A1L3JLA7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850252:LPB136 RS09510
gene id: 1850252:LPB136_RS09510
uniprot id: A0A1L3JKF5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1850252:LPB136 RS03670
gene id: 1850252:LPB136_RS03670
uniprot id: A0A1L3JHG9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1850252:LPB136 RS13140
gene id: 1850252:LPB136_RS13140
uniprot id: A0A1L3JMA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1850252:LPB136 RS02405
gene id: 1850252:LPB136_RS02405
uniprot id: A0A1L3JGL9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1850252:LPB136 RS00930
gene id: 1850252:LPB136_RS00930
uniprot id: A0A1L3JFW0
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS12345
gene id: 1850252:LPB136_RS12345
uniprot id: A0A1L3JLY1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1850252:LPB136 RS11475
gene id: 1850252:LPB136_RS11475
uniprot id: A0A1L3JLB0
names: Similarity
messages: Belongs to the P(II) protein family.

1850252:LPB136 RS11655
gene id: 1850252:LPB136_RS11655
uniprot id: A0A1L3JLG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1850252:LPB136 RS10800
gene id: 1850252:LPB136_RS10800
uniprot id: A0A1L3JL36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1850252:LPB136 RS12675
gene id: 1850252:LPB136_RS12675
uniprot id: A0A1L3JM36
names: Similarity
messages: Belongs to the sigma-54 factor family.

1850252:LPB136 RS11670
gene id: 1850252:LPB136_RS11670
uniprot id: A0A1L3JLH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1850252:LPB136 RS01295
gene id: 1850252:LPB136_RS01295
uniprot id: A0A1L3JG84
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1850252:LPB136 RS02300
gene id: 1850252:LPB136_RS02300
uniprot id: A0A1L3JGL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1850252:LPB136 RS03865
gene id: 1850252:LPB136_RS03865
uniprot id: A0A1L3JHE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1850252:LPB136 RS08340
gene id: 1850252:LPB136_RS08340
uniprot id: A0A1L3JJN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1850252:LPB136 RS02605
gene id: 1850252:LPB136_RS02605
uniprot id: A0A1L3JGR2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1850252:LPB136 RS01440
gene id: 1850252:LPB136_RS01440
uniprot id: A0A1L3JG45
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1850252:LPB136 RS03640
gene id: 1850252:LPB136_RS03640
uniprot id: A0A1L3JHB2
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1850252:LPB136 RS10820
gene id: 1850252:LPB136_RS10820
uniprot id: A0A1L3JKY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1850252:LPB136 RS03945
gene id: 1850252:LPB136_RS03945
uniprot id: A0A1L3JHH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1850252:LPB136 RS11800
gene id: 1850252:LPB136_RS11800
uniprot id: A0A1L3JLJ1
names: Similarity
messages: Belongs to the ribF family.

1850252:LPB136 RS07195
gene id: 1850252:LPB136_RS07195
uniprot id: A0A1L3JJ28
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1850252:LPB136 RS02445
gene id: 1850252:LPB136_RS02445
uniprot id: A0A1L3JGN9
names: Similarity
messages: Belongs to the isochorismate synthase family.

1850252:LPB136 RS04150
gene id: 1850252:LPB136_RS04150
uniprot id: A0A1L3JHL9
names: Similarity
messages: Belongs to the HSP15 family.

1850252:LPB136 RS10590
gene id: 1850252:LPB136_RS10590
uniprot id: A0A1L3JKV6
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1850252:LPB136 RS11930
gene id: 1850252:LPB136_RS11930
uniprot id: A0A1L3JLQ6
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1850252:LPB136 RS01515
gene id: 1850252:LPB136_RS01515
uniprot id: A0A1L3JG75
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1850252:LPB136 RS00685
gene id: 1850252:LPB136_RS00685
uniprot id: A0A1L3JFT3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS01485
gene id: 1850252:LPB136_RS01485
uniprot id: A0A1L3JG72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1850252:LPB136 RS00220
gene id: 1850252:LPB136_RS00220
uniprot id: A0A1L3JFI0
names: Similarity
messages: Belongs to the SusD family.

1850252:LPB136 RS00330
gene id: 1850252:LPB136_RS00330
uniprot id: A0A1L3JFJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1850252:LPB136 RS13205
gene id: 1850252:LPB136_RS13205
uniprot id: A0A1L3JMD2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1850252:LPB136 RS12805
gene id: 1850252:LPB136_RS12805
uniprot id: A0A1L3JM34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1850252:LPB136 RS11985
gene id: 1850252:LPB136_RS11985
uniprot id: A0A1L3JLR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS12660
gene id: 1850252:LPB136_RS12660
uniprot id: A0A1L3JLX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1850252:LPB136 RS05025
gene id: 1850252:LPB136_RS05025
uniprot id: A0A1L3JI16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1850252:LPB136 RS03795
gene id: 1850252:LPB136_RS03795
uniprot id: A0A1L3JHB5
names: Similarity
messages: Belongs to the Skp family.

1850252:LPB136 RS01060
gene id: 1850252:LPB136_RS01060
uniprot id: A0A1L3JFZ3
names: Similarity
messages: Belongs to the LOG family.

1850252:LPB136 RS05575
gene id: 1850252:LPB136_RS05575
uniprot id: A0A1L3JI97
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS10440
gene id: 1850252:LPB136_RS10440
uniprot id: A0A1L3JKV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1850252:LPB136 RS10375
gene id: 1850252:LPB136_RS10375
uniprot id: A0A1L3JKR7
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS09755
gene id: 1850252:LPB136_RS09755
uniprot id: A0A1L3JKJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1850252:LPB136 RS12780
gene id: 1850252:LPB136_RS12780
uniprot id: A0A1L3JM56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1850252:LPB136 RS13230
gene id: 1850252:LPB136_RS13230
uniprot id: A0A1L3JMA0
names: Similarity
messages: Belongs to the peptidase M1 family.

1850252:LPB136 RS09475
gene id: 1850252:LPB136_RS09475
uniprot id: A0A1L3JK75
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS02560
gene id: 1850252:LPB136_RS02560
uniprot id: A0A1L3JGR0
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1850252:LPB136 RS03410
gene id: 1850252:LPB136_RS03410
uniprot id: A0A1L3JHB7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850252:LPB136 RS02830
gene id: 1850252:LPB136_RS02830
uniprot id: A0A1L3JGW6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS08015
gene id: 1850252:LPB136_RS08015
uniprot id: A0A1L3JJG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1850252:LPB136 RS10415
gene id: 1850252:LPB136_RS10415
uniprot id: A0A1L3JKW6
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

1850252:LPB136 RS08895
gene id: 1850252:LPB136_RS08895
uniprot id: A0A1L3JJY6
names: Similarity
messages: Belongs to the Skp family.

1850252:LPB136 RS11650
gene id: 1850252:LPB136_RS11650
uniprot id: A0A1L3JLG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1850252:LPB136 RS11455
gene id: 1850252:LPB136_RS11455
uniprot id: A0A1L3JMX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1850252:LPB136 RS03275
gene id: 1850252:LPB136_RS03275
uniprot id: A0A1L3JH46
names: Similarity
messages: Belongs to the threonine synthase family.

1850252:LPB136 RS00105
gene id: 1850252:LPB136_RS00105
uniprot id: A0A1L3JMH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1850252:LPB136 RS04365
gene id: 1850252:LPB136_RS04365
uniprot id: A0A1L3JHM3
names: Similarity
messages: Belongs to the argonaute family. Long pAgo subfamily.

1850252:LPB136 RS08330
gene id: 1850252:LPB136_RS08330
uniprot id: A0A1L3JJS0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1850252:LPB136 RS01005
gene id: 1850252:LPB136_RS01005
uniprot id: A0A1L3JFW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1850252:LPB136 RS06640
gene id: 1850252:LPB136_RS06640
uniprot id: A0A1L3JIV9
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS00985
gene id: 1850252:LPB136_RS00985
uniprot id: A0A1L3JFW7
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS07740
gene id: 1850252:LPB136_RS07740
uniprot id: A0A1L3JJB9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850252:LPB136 RS03755
gene id: 1850252:LPB136_RS03755
uniprot id: A0A1L3JHD9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1850252:LPB136 RS11910
gene id: 1850252:LPB136_RS11910
uniprot id: A0A1L3JLQ0
names: Similarity
messages: Belongs to the SCO1/2 family.

1850252:LPB136 RS12295
gene id: 1850252:LPB136_RS12295
uniprot id: A0A1L3JLW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1850252:LPB136 RS03170
gene id: 1850252:LPB136_RS03170
uniprot id: A0A1L3JH34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS04990
gene id: 1850252:LPB136_RS04990
uniprot id: A0A1L3JHY0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1850252:LPB136 RS04870
gene id: 1850252:LPB136_RS04870
uniprot id: A0A1L3JHY2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1850252:LPB136 RS08750
gene id: 1850252:LPB136_RS08750
uniprot id: A0A1L3JMZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1850252:LPB136 RS12855
gene id: 1850252:LPB136_RS12855
uniprot id: A0A1L3JM38
names: Subcellular Location Annotation
messages: Periplasm

1850252:LPB136 RS06845
gene id: 1850252:LPB136_RS06845
uniprot id: A0A1L3JMX6
names: Function
messages: May be involved in the biogenesis of curli organelles.

1850252:LPB136 RS11115
gene id: 1850252:LPB136_RS11115
uniprot id: A0A1L3JL92
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1850252:LPB136 RS10445
gene id: 1850252:LPB136_RS10445
uniprot id: A0A1L3JKT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1850252:LPB136 RS11525
gene id: 1850252:LPB136_RS11525
uniprot id: A0A1L3JLH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1850252:LPB136 RS07725
gene id: 1850252:LPB136_RS07725
uniprot id: A0A1L3JJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1850252:LPB136 RS10655
gene id: 1850252:LPB136_RS10655
uniprot id: A0A1L3JKZ5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1850252:LPB136 RS00390
gene id: 1850252:LPB136_RS00390
uniprot id: A0A1L3JFM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1850252:LPB136 RS03585
gene id: 1850252:LPB136_RS03585
uniprot id: A0A1L3JH97
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1850252:LPB136 RS11765
gene id: 1850252:LPB136_RS11765
uniprot id: A0A1L3JLG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS00260
gene id: 1850252:LPB136_RS00260
uniprot id: A0A1L3JFJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1850252:LPB136 RS05060
gene id: 1850252:LPB136_RS05060
uniprot id: A0A1L3JI62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1850252:LPB136 RS04745
gene id: 1850252:LPB136_RS04745
uniprot id: A0A1L3JHT7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1850252:LPB136 RS02185
gene id: 1850252:LPB136_RS02185
uniprot id: A0A1L3JGJ1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1850252:LPB136 RS07530
gene id: 1850252:LPB136_RS07530
uniprot id: A0A1L3JJ78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1850252:LPB136 RS12565
gene id: 1850252:LPB136_RS12565
uniprot id: A0A1L3JLZ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1850252:LPB136 RS01655
gene id: 1850252:LPB136_RS01655
uniprot id: A0A1L3JMM0
names: Similarity
messages: Belongs to the arginase family.

1850252:LPB136 RS07160
gene id: 1850252:LPB136_RS07160
uniprot id: A0A1L3JJ39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Heterotrimer of A, B and C subunits.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS10035
gene id: 1850252:LPB136_RS10035
uniprot id: A0A1L3JKM1
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS05300
gene id: 1850252:LPB136_RS05300
uniprot id: A0A1L3JI38
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1850252:LPB136 RS06720
gene id: 1850252:LPB136_RS06720
uniprot id: A0A1L3JIU8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS04585
gene id: 1850252:LPB136_RS04585
uniprot id: A0A1L3JHS7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1850252:LPB136 RS12005
gene id: 1850252:LPB136_RS12005
uniprot id: A0A1L3JLK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1850252:LPB136 RS07815
gene id: 1850252:LPB136_RS07815
uniprot id: A0A1L3JJD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1850252:LPB136 RS10520
gene id: 1850252:LPB136_RS10520
uniprot id: A0A1L3JKY6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1850252:LPB136 RS02355
gene id: 1850252:LPB136_RS02355
uniprot id: A0A1L3JGK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1850252:LPB136 RS11045
gene id: 1850252:LPB136_RS11045
uniprot id: A0A1L3JL56
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1850252:LPB136 RS12630
gene id: 1850252:LPB136_RS12630
uniprot id: A0A1L3JM37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1850252:LPB136 RS06040
gene id: 1850252:LPB136_RS06040
uniprot id: A0A1L3JII4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS03215
gene id: 1850252:LPB136_RS03215
uniprot id: A0A1L3JH37
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1850252:LPB136 RS13185
gene id: 1850252:LPB136_RS13185
uniprot id: A0A1L3JME7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1850252:LPB136 RS02945
gene id: 1850252:LPB136_RS02945
uniprot id: A0A1L3JH26
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1850252:LPB136 RS12705
gene id: 1850252:LPB136_RS12705
uniprot id: A0A1L3JM49
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1850252:LPB136 RS08160
gene id: 1850252:LPB136_RS08160
uniprot id: A0A1L3JJK8
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS08810
gene id: 1850252:LPB136_RS08810
uniprot id: A0A1L3JJX5
names: Similarity
messages: Belongs to the NAD synthetase family.

1850252:LPB136 RS12335
gene id: 1850252:LPB136_RS12335
uniprot id: A0A1L3JLS2
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS02550
gene id: 1850252:LPB136_RS02550
uniprot id: A0A1L3JGQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1850252:LPB136 RS11075
gene id: 1850252:LPB136_RS11075
uniprot id: A0A1L3JL98
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1850252:LPB136 RS05290
gene id: 1850252:LPB136_RS05290
uniprot id: A0A1L3JI58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1850252:LPB136 RS08755
gene id: 1850252:LPB136_RS08755
uniprot id: A0A1L3JJW7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1850252:LPB136 RS11740
gene id: 1850252:LPB136_RS11740
uniprot id: A0A1L3JLF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

1850252:LPB136 RS12655
gene id: 1850252:LPB136_RS12655
uniprot id: A0A1L3JM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1850252:LPB136 RS08085
gene id: 1850252:LPB136_RS08085
uniprot id: A0A1L3JJN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1850252:LPB136 RS02750
gene id: 1850252:LPB136_RS02750
uniprot id: A0A1L3JGV7
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS13570
gene id: 1850252:LPB136_RS13570
uniprot id: A0A1L3JMG8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1850252:LPB136 RS03045
gene id: 1850252:LPB136_RS03045
uniprot id: A0A1L3JGZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1850252:LPB136 RS04465
gene id: 1850252:LPB136_RS04465
uniprot id: A0A1L3JMN0
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1850252:LPB136 RS06475
gene id: 1850252:LPB136_RS06475
uniprot id: A0A1L3JIP4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1850252:LPB136 RS10060
gene id: 1850252:LPB136_RS10060
uniprot id: A0A1L3JKR6
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1850252:LPB136 RS10065
gene id: 1850252:LPB136_RS10065
uniprot id: A0A1L3JKK6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1850252:LPB136 RS07590
gene id: 1850252:LPB136_RS07590
uniprot id: A0A1L3JJA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS02960
gene id: 1850252:LPB136_RS02960
uniprot id: A0A1L3JGW7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1850252:LPB136 RS06165
gene id: 1850252:LPB136_RS06165
uniprot id: A0A1L3JIJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1850252:LPB136 RS12620
gene id: 1850252:LPB136_RS12620
uniprot id: A0A1L3JM31
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS10880
gene id: 1850252:LPB136_RS10880
uniprot id: A0A1L3JL29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850252:LPB136 RS12215
gene id: 1850252:LPB136_RS12215
uniprot id: A0A1L3JLN7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1850252:LPB136 RS01520
gene id: 1850252:LPB136_RS01520
uniprot id: A0A1L3JG71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1850252:LPB136 RS12115
gene id: 1850252:LPB136_RS12115
uniprot id: A0A1L3JLR1
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1850252:LPB136 RS11360
gene id: 1850252:LPB136_RS11360
uniprot id: A0A1L3JL94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1850252:LPB136 RS08245
gene id: 1850252:LPB136_RS08245
uniprot id: A0A1L3JJR6
names: Similarity
messages: Belongs to the peptidase C40 family.

1850252:LPB136 RS07790
gene id: 1850252:LPB136_RS07790
uniprot id: A0A1L3JJD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1850252:LPB136 RS11495
gene id: 1850252:LPB136_RS11495
uniprot id: A0A1L3JLD6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1850252:LPB136 RS13225
gene id: 1850252:LPB136_RS13225
uniprot id: A0A1L3JM84
names: Similarity
messages: Belongs to the thioredoxin family.

1850252:LPB136 RS11355
gene id: 1850252:LPB136_RS11355
uniprot id: A0A1L3JLE8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850252:LPB136 RS03030
gene id: 1850252:LPB136_RS03030
uniprot id: A0A1L3JH02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1850252:LPB136 RS02760
gene id: 1850252:LPB136_RS02760
uniprot id: A0A1L3JGW5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850252:LPB136 RS11890
gene id: 1850252:LPB136_RS11890
uniprot id: A0A1L3JLI7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1850252:LPB136 RS03250
gene id: 1850252:LPB136_RS03250
uniprot id: A0A1L3JH14
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1850252:LPB136 RS08470
gene id: 1850252:LPB136_RS08470
uniprot id: A0A1L3JJT8
names: Similarity
messages: Belongs to the proline racemase family.

1850252:LPB136 RS03190
gene id: 1850252:LPB136_RS03190
uniprot id: A0A1L3JMS7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1850252:LPB136 RS12700
gene id: 1850252:LPB136_RS12700
uniprot id: A0A1L3JM14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1850252:LPB136 RS05850
gene id: 1850252:LPB136_RS05850
uniprot id: A0A1L3JIG8
names: Similarity
messages: Belongs to the pirin family.

1850252:LPB136 RS12220
gene id: 1850252:LPB136_RS12220
uniprot id: A0A1L3JLS1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1850252:LPB136 RS06230
gene id: 1850252:LPB136_RS06230
uniprot id: A0A1L3JIM0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1850252:LPB136 RS01205
gene id: 1850252:LPB136_RS01205
uniprot id: A0A1L3JG01
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS10025
gene id: 1850252:LPB136_RS10025
uniprot id: A0A1L3JKM0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850252:LPB136 RS10005
gene id: 1850252:LPB136_RS10005
uniprot id: A0A1L3JKQ7
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1850252:LPB136 RS01145
gene id: 1850252:LPB136_RS01145
uniprot id: A0A1L3JFY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1850252:LPB136 RS13000
gene id: 1850252:LPB136_RS13000
uniprot id: A0A1L3JM91
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1850252:LPB136 RS10370
gene id: 1850252:LPB136_RS10370
uniprot id: A0A1L3JKX3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1850252:LPB136 RS12685
gene id: 1850252:LPB136_RS12685
uniprot id: A0A1L3JLY6
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS00395
gene id: 1850252:LPB136_RS00395
uniprot id: A0A1L3JFL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1850252:LPB136 RS03330
gene id: 1850252:LPB136_RS03330
uniprot id: A0A1L3JH55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1850252:LPB136 RS09245
gene id: 1850252:LPB136_RS09245
uniprot id: A0A1L3JKA2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1850252:LPB136 RS05750
gene id: 1850252:LPB136_RS05750
uniprot id: A0A1L3JIC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1850252:LPB136 RS10290
gene id: 1850252:LPB136_RS10290
uniprot id: A0A1L3JKS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1850252:LPB136 RS08130
gene id: 1850252:LPB136_RS08130
uniprot id: A0A1L3JJP4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1850252:LPB136 RS00980
gene id: 1850252:LPB136_RS00980
uniprot id: A0A1L3JFX3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1850252:LPB136 RS05015
gene id: 1850252:LPB136_RS05015
uniprot id: A0A1L3JHZ6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1850252:LPB136 RS12920
gene id: 1850252:LPB136_RS12920
uniprot id: A0A1L3JM97
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

1850252:LPB136 RS07090
gene id: 1850252:LPB136_RS07090
uniprot id: A0A1L3JIZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1850252:LPB136 RS09175
gene id: 1850252:LPB136_RS09175
uniprot id: A0A1L3JK70
names: Similarity
messages: Belongs to the sterol desaturase family.

1850252:LPB136 RS01430
gene id: 1850252:LPB136_RS01430
uniprot id: A0A1L3JG59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1850252:LPB136 RS07860
gene id: 1850252:LPB136_RS07860
uniprot id: A0A1L3JJE3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1850252:LPB136 RS13025
gene id: 1850252:LPB136_RS13025
uniprot id: A0A1L3JM74
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1850252:LPB136 RS02905
gene id: 1850252:LPB136_RS02905
uniprot id: A0A1L3JGX7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS05480
gene id: 1850252:LPB136_RS05480
uniprot id: A0A1L3JI95
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1850252:LPB136 RS04035
gene id: 1850252:LPB136_RS04035
uniprot id: A0A1L3JHG4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1850252:LPB136 RS02465
gene id: 1850252:LPB136_RS02465
uniprot id: A0A1L3JML1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1850252:LPB136 RS13195
gene id: 1850252:LPB136_RS13195
uniprot id: A0A1L3JMB3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1850252:LPB136 RS12015
gene id: 1850252:LPB136_RS12015
uniprot id: A0A1L3JLN9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1850252:LPB136 RS01895
gene id: 1850252:LPB136_RS01895
uniprot id: A0A1L3JGD4
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS01110
gene id: 1850252:LPB136_RS01110
uniprot id: A0A1L3JMP1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1850252:LPB136 RS03710
gene id: 1850252:LPB136_RS03710
uniprot id: A0A1L3JHB1
names: Similarity
messages: Belongs to the DEAD box helicase family.

1850252:LPB136 RS09885
gene id: 1850252:LPB136_RS09885
uniprot id: A0A1L3JKN5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1850252:LPB136 RS08905
gene id: 1850252:LPB136_RS08905
uniprot id: A0A1L3JJZ2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1850252:LPB136 RS07565
gene id: 1850252:LPB136_RS07565
uniprot id: A0A1L3JJC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1850252:LPB136 RS02070
gene id: 1850252:LPB136_RS02070
uniprot id: A0A1L3JGM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1850252:LPB136 RS08260
gene id: 1850252:LPB136_RS08260
uniprot id: A0A1L3JJM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1850252:LPB136 RS06980
gene id: 1850252:LPB136_RS06980
uniprot id: A0A1L3JJ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1850252:LPB136 RS13020
gene id: 1850252:LPB136_RS13020
uniprot id: A0A1L3JM65
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1850252:LPB136 RS00140
gene id: 1850252:LPB136_RS00140
uniprot id: A0A1L3JFG1
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1850252:LPB136 RS05990
gene id: 1850252:LPB136_RS05990
uniprot id: A0A1L3JII3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1850252:LPB136 RS11450
gene id: 1850252:LPB136_RS11450
uniprot id: A0A1L3JLD9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1850252:LPB136 RS05845
gene id: 1850252:LPB136_RS05845
uniprot id: A0A1L3JMR0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1850252:LPB136 RS08815
gene id: 1850252:LPB136_RS08815
uniprot id: A0A1L3JJY4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1850252:LPB136 RS09615
gene id: 1850252:LPB136_RS09615
uniprot id: A0A1L3JKI3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1850252:LPB136 RS00670
gene id: 1850252:LPB136_RS00670
uniprot id: A0A1L3JFQ9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1850252:LPB136 RS12290
gene id: 1850252:LPB136_RS12290
uniprot id: A0A1L3JLU4
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1850252:LPB136 RS07050
gene id: 1850252:LPB136_RS07050
uniprot id: A0A1L3JJ45
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS05760
gene id: 1850252:LPB136_RS05760
uniprot id: A0A1L3JIE1
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1850252:LPB136 RS10165
gene id: 1850252:LPB136_RS10165
uniprot id: A0A1L3JKM3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS12210
gene id: 1850252:LPB136_RS12210
uniprot id: A0A1L3JLP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1850252:LPB136 RS09570
gene id: 1850252:LPB136_RS09570
uniprot id: A0A1L3JKB3
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS11205
gene id: 1850252:LPB136_RS11205
uniprot id: A0A1L3JLB7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1850252:LPB136 RS11565
gene id: 1850252:LPB136_RS11565
uniprot id: A0A1L3JLF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1850252:LPB136 RS03280
gene id: 1850252:LPB136_RS03280
uniprot id: A0A1L3JH35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS07325
gene id: 1850252:LPB136_RS07325
uniprot id: A0A1L3JJ94
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1850252:LPB136 RS03230
gene id: 1850252:LPB136_RS03230
uniprot id: A0A1L3JH17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

1850252:LPB136 RS01705
gene id: 1850252:LPB136_RS01705
uniprot id: A0A1L3JGA5
names: Similarity
messages: Belongs to the CarB family.

1850252:LPB136 RS08540
gene id: 1850252:LPB136_RS08540
uniprot id: A0A1L3JJT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1850252:LPB136 RS07245
gene id: 1850252:LPB136_RS07245
uniprot id: A0A1L3JJ41
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1850252:LPB136 RS10530
gene id: 1850252:LPB136_RS10530
uniprot id: A0A1L3JL02
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1850252:LPB136 RS11555
gene id: 1850252:LPB136_RS11555
uniprot id: A0A1L3JLH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1850252:LPB136 RS07280
gene id: 1850252:LPB136_RS07280
uniprot id: A0A1L3JJ33
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS07535
gene id: 1850252:LPB136_RS07535
uniprot id: A0A1L3JJB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1850252:LPB136 RS13040
gene id: 1850252:LPB136_RS13040
uniprot id: A0A1L3JM79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1850252:LPB136 RS10770
gene id: 1850252:LPB136_RS10770
uniprot id: A0A1L3JL15
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850252:LPB136 RS02690
gene id: 1850252:LPB136_RS02690
uniprot id: A0A1L3JGU2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1850252:LPB136 RS00085
gene id: 1850252:LPB136_RS00085
uniprot id: A0A1L3JFF3
names: Subunit
messages: Monomer.

1850252:LPB136 RS03340
gene id: 1850252:LPB136_RS03340
uniprot id: A0A1L3JMT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1850252:LPB136 RS10030
gene id: 1850252:LPB136_RS10030
uniprot id: A0A1L3JKL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1850252:LPB136 RS00410
gene id: 1850252:LPB136_RS00410
uniprot id: A0A1L3JFS8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1850252:LPB136 RS05525
gene id: 1850252:LPB136_RS05525
uniprot id: A0A1L3JI87
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850252:LPB136 RS09655
gene id: 1850252:LPB136_RS09655
uniprot id: A0A1L3JKH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1850252:LPB136 RS04690
gene id: 1850252:LPB136_RS04690
uniprot id: A0A1L3JMU7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1850252:LPB136 RS10420
gene id: 1850252:LPB136_RS10420
uniprot id: A0A1L3JKX1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1850252:LPB136 RS00385
gene id: 1850252:LPB136_RS00385
uniprot id: A0A1L3JFK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1850252:LPB136 RS07630
gene id: 1850252:LPB136_RS07630
uniprot id: A0A1L3JJA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1850252:LPB136 RS09705
gene id: 1850252:LPB136_RS09705
uniprot id: A0A1L3JKI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1850252:LPB136 RS00630
gene id: 1850252:LPB136_RS00630
uniprot id: A0A1L3JFQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1850252:LPB136 RS00415
gene id: 1850252:LPB136_RS00415
uniprot id: A0A1L3JFN3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1850252:LPB136 RS08040
gene id: 1850252:LPB136_RS08040
uniprot id: A0A1L3JJG5
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS07315
gene id: 1850252:LPB136_RS07315
uniprot id: A0A1L3JJ47
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS11190
gene id: 1850252:LPB136_RS11190
uniprot id: A0A1L3JL50
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1850252:LPB136 RS00120
gene id: 1850252:LPB136_RS00120
uniprot id: A0A1L3JFF2
names: Similarity
messages: Belongs to the peptidase S8 family.

1850252:LPB136 RS00365
gene id: 1850252:LPB136_RS00365
uniprot id: A0A1L3JFK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1850252:LPB136 RS07300
gene id: 1850252:LPB136_RS07300
uniprot id: A0A1L3JJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1850252:LPB136 RS05835
gene id: 1850252:LPB136_RS05835
uniprot id: A0A1L3JIH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1850252:LPB136 RS10215
gene id: 1850252:LPB136_RS10215
uniprot id: A0A1L3JKN3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS10710
gene id: 1850252:LPB136_RS10710
uniprot id: A0A1L3JKZ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1850252:LPB136 RS01695
gene id: 1850252:LPB136_RS01695
uniprot id: A0A1L3JGA6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS08315
gene id: 1850252:LPB136_RS08315
uniprot id: A0A1L3JJN2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1850252:LPB136 RS01925
gene id: 1850252:LPB136_RS01925
uniprot id: A0A1L3JGE3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1850252:LPB136 RS00335
gene id: 1850252:LPB136_RS00335
uniprot id: A0A1L3JFM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1850252:LPB136 RS01410
gene id: 1850252:LPB136_RS01410
uniprot id: A0A1L3JG53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1850252:LPB136 RS10980
gene id: 1850252:LPB136_RS10980
uniprot id: A0A1L3JL25
names: Similarity
messages: Belongs to the peptidase S8 family.

1850252:LPB136 RS07005
gene id: 1850252:LPB136_RS07005
uniprot id: A0A1L3JJ11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1850252:LPB136 RS10855
gene id: 1850252:LPB136_RS10855
uniprot id: A0A1L3JL42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1850252:LPB136 RS01335
gene id: 1850252:LPB136_RS01335
uniprot id: A0A1L3JG40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1850252:LPB136 RS08440
gene id: 1850252:LPB136_RS08440
uniprot id: A0A1L3JJR1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1850252:LPB136 RS08250
gene id: 1850252:LPB136_RS08250
uniprot id: A0A1L3JJP6
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1850252:LPB136 RS09690
gene id: 1850252:LPB136_RS09690
uniprot id: A0A1L3JKG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1850252:LPB136 RS02855
gene id: 1850252:LPB136_RS02855
uniprot id: A0A1L3JGW1
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS03730
gene id: 1850252:LPB136_RS03730
uniprot id: A0A1L3JMM2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1850252:LPB136 RS03300
gene id: 1850252:LPB136_RS03300
uniprot id: A0A1L3JH64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1850252:LPB136 RS10350
gene id: 1850252:LPB136_RS10350
uniprot id: A0A1L3JKP9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1850252:LPB136 RS00320
gene id: 1850252:LPB136_RS00320
uniprot id: A0A1L3JFK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1850252:LPB136 RS08050
gene id: 1850252:LPB136_RS08050
uniprot id: A0A1L3JJL2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1850252:LPB136 RS01760
gene id: 1850252:LPB136_RS01760
uniprot id: A0A1L3JGA0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1850252:LPB136 RS12525
gene id: 1850252:LPB136_RS12525
uniprot id: A0A1L3JM21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1850252:LPB136 RS01815
gene id: 1850252:LPB136_RS01815
uniprot id: A0A1L3JGC6
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1850252:LPB136 RS05700
gene id: 1850252:LPB136_RS05700
uniprot id: A0A1L3JIA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850252:LPB136 RS07615
gene id: 1850252:LPB136_RS07615
uniprot id: A0A1L3JJD8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1850252:LPB136 RS03745
gene id: 1850252:LPB136_RS03745
uniprot id: A0A1L3JHD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850252:LPB136 RS06870
gene id: 1850252:LPB136_RS06870
uniprot id: A0A1L3JIZ6
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS13065
gene id: 1850252:LPB136_RS13065
uniprot id: A0A1L3JM52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1850252:LPB136 RS00275
gene id: 1850252:LPB136_RS00275
uniprot id: A0A1L3JFI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1850252:LPB136 RS07080
gene id: 1850252:LPB136_RS07080
uniprot id: A0A1L3JJ30
names: Similarity
messages: Belongs to the GbsR family.

1850252:LPB136 RS08505
gene id: 1850252:LPB136_RS08505
uniprot id: A0A1L3JJU8
names: Similarity
messages: Belongs to the proline racemase family.

1850252:LPB136 RS10455
gene id: 1850252:LPB136_RS10455
uniprot id: A0A1L3JKS2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1850252:LPB136 RS03490
gene id: 1850252:LPB136_RS03490
uniprot id: A0A1L3JH72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1850252:LPB136 RS06620
gene id: 1850252:LPB136_RS06620
uniprot id: A0A1L3JIV3
names: Subcellular Location Annotation
messages: Membrane

1850252:LPB136 RS11705
gene id: 1850252:LPB136_RS11705
uniprot id: A0A1L3JLH2
names: Similarity
messages: Belongs to the RecJ family.

1850252:LPB136 RS01340
gene id: 1850252:LPB136_RS01340
uniprot id: A0A1L3JG29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1850252:LPB136 RS02380
gene id: 1850252:LPB136_RS02380
uniprot id: A0A1L3JGT4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.