1850246:LPB138 RS05985
gene id: 1850246:LPB138_RS05985
uniprot id: A0A1D8P6R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1850246:LPB138 RS12555
gene id: 1850246:LPB138_RS12555
uniprot id: A0A1D8PA39
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS13815
gene id: 1850246:LPB138_RS13815
uniprot id: A0A1D8PAW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1850246:LPB138 RS13450
gene id: 1850246:LPB138_RS13450
uniprot id: A0A1D8PAL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1850246:LPB138 RS04285
gene id: 1850246:LPB138_RS04285
uniprot id: A0A1D8P5W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1850246:LPB138 RS03930
gene id: 1850246:LPB138_RS03930
uniprot id: A0A1D8P5L3
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS07205
gene id: 1850246:LPB138_RS07205
uniprot id: A0A1D8P7B8
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1850246:LPB138 RS02855
gene id: 1850246:LPB138_RS02855
uniprot id: A0A1D8P543
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1850246:LPB138 RS12140
gene id: 1850246:LPB138_RS12140
uniprot id: A0A1D8P9W7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1850246:LPB138 RS05000
gene id: 1850246:LPB138_RS05000
uniprot id: A0A1D8P682
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1850246:LPB138 RS11895
gene id: 1850246:LPB138_RS11895
uniprot id: A0A1D8P9R3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

1850246:LPB138 RS13955
gene id: 1850246:LPB138_RS13955
uniprot id: A0A1D8PAV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1850246:LPB138 RS12065
gene id: 1850246:LPB138_RS12065
uniprot id: A0A1D8P9V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1850246:LPB138 RS02605
gene id: 1850246:LPB138_RS02605
uniprot id: A0A1D8P504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1850246:LPB138 RS02015
gene id: 1850246:LPB138_RS02015
uniprot id: A0A1D8PBP9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1850246:LPB138 RS07020
gene id: 1850246:LPB138_RS07020
uniprot id: A0A1D8P7C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1850246:LPB138 RS13355
gene id: 1850246:LPB138_RS13355
uniprot id: A0A1D8PAN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1850246:LPB138 RS13970
gene id: 1850246:LPB138_RS13970
uniprot id: A0A1D8PAX0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1850246:LPB138 RS02140
gene id: 1850246:LPB138_RS02140
uniprot id: A0A1D8P4M8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1850246:LPB138 RS14410
gene id: 1850246:LPB138_RS14410
uniprot id: A0A1D8PB46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1850246:LPB138 RS12580
gene id: 1850246:LPB138_RS12580
uniprot id: A0A1D8PA83
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1850246:LPB138 RS10960
gene id: 1850246:LPB138_RS10960
uniprot id: A0A1D8P9E5
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS13095
gene id: 1850246:LPB138_RS13095
uniprot id: A0A1D8PAC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850246:LPB138 RS04330
gene id: 1850246:LPB138_RS04330
uniprot id: A0A1D8PBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1850246:LPB138 RS01990
gene id: 1850246:LPB138_RS01990
uniprot id: A0A1D8P4L9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1850246:LPB138 RS08060
gene id: 1850246:LPB138_RS08060
uniprot id: A0A1D8P7V7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS14415
gene id: 1850246:LPB138_RS14415
uniprot id: A0A1D8PB40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1850246:LPB138 RS10915
gene id: 1850246:LPB138_RS10915
uniprot id: A0A1D8P9B3
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1850246:LPB138 RS02840
gene id: 1850246:LPB138_RS02840
uniprot id: A0A1D8P583
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-56 and Arg-59) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1850246:LPB138 RS11375
gene id: 1850246:LPB138_RS11375
uniprot id: A0A1D8P9M1
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1850246:LPB138 RS10215
gene id: 1850246:LPB138_RS10215
uniprot id: A0A1D8P8Y4
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1850246:LPB138 RS01735
gene id: 1850246:LPB138_RS01735
uniprot id: A0A1D8PBN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1850246:LPB138 RS14745
gene id: 1850246:LPB138_RS14745
uniprot id: A0A1D8PBA6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1850246:LPB138 RS03525
gene id: 1850246:LPB138_RS03525
uniprot id: A0A1D8P5F8
names: Similarity
messages: Belongs to the peptidase S8 family.

1850246:LPB138 RS00355
gene id: 1850246:LPB138_RS00355
uniprot id: A0A1D8P3R6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1850246:LPB138 RS03175
gene id: 1850246:LPB138_RS03175
uniprot id: A0A1D8P584
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1850246:LPB138 RS07130
gene id: 1850246:LPB138_RS07130
uniprot id: A0A1D8P7B9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1850246:LPB138 RS14890
gene id: 1850246:LPB138_RS14890
uniprot id: A0A1D8PBD1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS06695
gene id: 1850246:LPB138_RS06695
uniprot id: A0A1D8P734
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1850246:LPB138 RS14430
gene id: 1850246:LPB138_RS14430
uniprot id: A0A1D8PB53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1850246:LPB138 RS03070
gene id: 1850246:LPB138_RS03070
uniprot id: A0A1D8P568
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1850246:LPB138 RS04790
gene id: 1850246:LPB138_RS04790
uniprot id: A0A1D8P644
names: Similarity
messages: Belongs to the BshC family.

1850246:LPB138 RS04730
gene id: 1850246:LPB138_RS04730
uniprot id: A0A1D8P630
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS04310
gene id: 1850246:LPB138_RS04310
uniprot id: A0A1D8PBR4
names: Similarity
messages: Belongs to the peptidase S51 family.

1850246:LPB138 RS02730
gene id: 1850246:LPB138_RS02730
uniprot id: A0A1D8P4Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1850246:LPB138 RS13025
gene id: 1850246:LPB138_RS13025
uniprot id: A0A1D8PAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850246:LPB138 RS05530
gene id: 1850246:LPB138_RS05530
uniprot id: A0A1D8P6J1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1850246:LPB138 RS02660
gene id: 1850246:LPB138_RS02660
uniprot id: A0A1D8P506
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1850246:LPB138 RS00560
gene id: 1850246:LPB138_RS00560
uniprot id: A0A1D8P3X0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1850246:LPB138 RS05630
gene id: 1850246:LPB138_RS05630
uniprot id: A0A1D8P6L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1850246:LPB138 RS05660
gene id: 1850246:LPB138_RS05660
uniprot id: A0A1D8P6N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1850246:LPB138 RS06135
gene id: 1850246:LPB138_RS06135
uniprot id: A0A1D8P6T2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

1850246:LPB138 RS07480
gene id: 1850246:LPB138_RS07480
uniprot id: A0A1D8P7H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1850246:LPB138 RS06490
gene id: 1850246:LPB138_RS06490
uniprot id: A0A1D8P716
names: Similarity
messages: Belongs to the glutamate synthase family.

1850246:LPB138 RS12805
gene id: 1850246:LPB138_RS12805
uniprot id: A0A1D8PAB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1850246:LPB138 RS15000
gene id: 1850246:LPB138_RS15000
uniprot id: A0A1D8PBG6
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS07685
gene id: 1850246:LPB138_RS07685
uniprot id: A0A1D8P7L0
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1850246:LPB138 RS11090
gene id: 1850246:LPB138_RS11090
uniprot id: A0A1D8P9D9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1850246:LPB138 RS09955
gene id: 1850246:LPB138_RS09955
uniprot id: A0A1D8P8U9
names: Similarity
messages: Belongs to the SufE family.

1850246:LPB138 RS12650
gene id: 1850246:LPB138_RS12650
uniprot id: A0A1D8PA75
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1850246:LPB138 RS00400
gene id: 1850246:LPB138_RS00400
uniprot id: A0A1D8P3Y0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1850246:LPB138 RS04440
gene id: 1850246:LPB138_RS04440
uniprot id: A0A1D8P5W5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1850246:LPB138 RS14520
gene id: 1850246:LPB138_RS14520
uniprot id: A0A1D8PBD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1850246:LPB138 RS13380
gene id: 1850246:LPB138_RS13380
uniprot id: A0A1D8PAJ8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1850246:LPB138 RS06650
gene id: 1850246:LPB138_RS06650
uniprot id: A0A1D8P729
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS07380
gene id: 1850246:LPB138_RS07380
uniprot id: A0A1D8P7G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1850246:LPB138 RS12110
gene id: 1850246:LPB138_RS12110
uniprot id: A0A1D8P9U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1850246:LPB138 RS15185
gene id: 1850246:LPB138_RS15185
uniprot id: A0A1D8PBJ3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1850246:LPB138 RS15120
gene id: 1850246:LPB138_RS15120
uniprot id: A0A1D8PBH9
names: Similarity
messages: Belongs to the DinB family.

1850246:LPB138 RS07585
gene id: 1850246:LPB138_RS07585
uniprot id: A0A1D8P7J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1850246:LPB138 RS09675
gene id: 1850246:LPB138_RS09675
uniprot id: A0A1D8P8R9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS07990
gene id: 1850246:LPB138_RS07990
uniprot id: A0A1D8P7S3
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1850246:LPB138 RS10715
gene id: 1850246:LPB138_RS10715
uniprot id: A0A1D8P972
names: Similarity
messages: Belongs to the Skp family.

1850246:LPB138 RS13330
gene id: 1850246:LPB138_RS13330
uniprot id: A0A1D8PAI7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS12135
gene id: 1850246:LPB138_RS12135
uniprot id: A0A1D8PBY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1850246:LPB138 RS07715
gene id: 1850246:LPB138_RS07715
uniprot id: A0A1D8P7P0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1850246:LPB138 RS01520
gene id: 1850246:LPB138_RS01520
uniprot id: A0A1D8P4C4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1850246:LPB138 RS07010
gene id: 1850246:LPB138_RS07010
uniprot id: A0A1D8PBX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1850246:LPB138 RS01580
gene id: 1850246:LPB138_RS01580
uniprot id: A0A1D8P4E2
names: Similarity
messages: Belongs to the threonine aldolase family.

1850246:LPB138 RS05595
gene id: 1850246:LPB138_RS05595
uniprot id: A0A1D8P6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS09800
gene id: 1850246:LPB138_RS09800
uniprot id: A0A1D8P8N7
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS09925
gene id: 1850246:LPB138_RS09925
uniprot id: A0A1D8P8R5
names: Similarity
messages: Belongs to the aspartokinase family.

1850246:LPB138 RS04250
gene id: 1850246:LPB138_RS04250
uniprot id: A0A1D8P5U6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1850246:LPB138 RS04850
gene id: 1850246:LPB138_RS04850
uniprot id: A0A1D8P650
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1850246:LPB138 RS04630
gene id: 1850246:LPB138_RS04630
uniprot id: A0A1D8P626
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1850246:LPB138 RS08155
gene id: 1850246:LPB138_RS08155
uniprot id: A0A1D8P7U2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1850246:LPB138 RS14460
gene id: 1850246:LPB138_RS14460
uniprot id: A0A1D8PB56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1850246:LPB138 RS14825
gene id: 1850246:LPB138_RS14825
uniprot id: A0A1D8PBD2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS07190
gene id: 1850246:LPB138_RS07190
uniprot id: A0A1D8P7B0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1850246:LPB138 RS02690
gene id: 1850246:LPB138_RS02690
uniprot id: A0A1D8P4X4
names: Similarity
messages: Belongs to the Skp family.

1850246:LPB138 RS06950
gene id: 1850246:LPB138_RS06950
uniprot id: A0A1D8P768
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1850246:LPB138 RS02575
gene id: 1850246:LPB138_RS02575
uniprot id: A0A1D8P537
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1850246:LPB138 RS01805
gene id: 1850246:LPB138_RS01805
uniprot id: A0A1D8P4I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1850246:LPB138 RS00545
gene id: 1850246:LPB138_RS00545
uniprot id: A0A1D8P3X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1850246:LPB138 RS13550
gene id: 1850246:LPB138_RS13550
uniprot id: A0A1D8PAQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS11410
gene id: 1850246:LPB138_RS11410
uniprot id: A0A1D8P9J1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1850246:LPB138 RS01425
gene id: 1850246:LPB138_RS01425
uniprot id: A0A1D8PBK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1850246:LPB138 RS12795
gene id: 1850246:LPB138_RS12795
uniprot id: A0A1D8PAB2
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1850246:LPB138 RS08330
gene id: 1850246:LPB138_RS08330
uniprot id: A0A1D8P814
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1850246:LPB138 RS03970
gene id: 1850246:LPB138_RS03970
uniprot id: A0A1D8P5M6
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS07370
gene id: 1850246:LPB138_RS07370
uniprot id: A0A1D8P7G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1850246:LPB138 RS08990
gene id: 1850246:LPB138_RS08990
uniprot id: A0A1D8P8C7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1850246:LPB138 RS13080
gene id: 1850246:LPB138_RS13080
uniprot id: A0A1D8PAG8
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS11810
gene id: 1850246:LPB138_RS11810
uniprot id: A0A1D8P9Q3
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS08350
gene id: 1850246:LPB138_RS08350
uniprot id: A0A1D8P7Y6
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

1850246:LPB138 RS04610
gene id: 1850246:LPB138_RS04610
uniprot id: A0A1D8P5Z6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1850246:LPB138 RS09985
gene id: 1850246:LPB138_RS09985
uniprot id: A0A1D8P8Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1850246:LPB138 RS02365
gene id: 1850246:LPB138_RS02365
uniprot id: A0A1D8P4S2
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS10185
gene id: 1850246:LPB138_RS10185
uniprot id: A0A1D8P8Y7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1850246:LPB138 RS08405
gene id: 1850246:LPB138_RS08405
uniprot id: A0A1D8P7Y7
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1850246:LPB138 RS14420
gene id: 1850246:LPB138_RS14420
uniprot id: A0A1D8PB99
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1850246:LPB138 RS09060
gene id: 1850246:LPB138_RS09060
uniprot id: A0A1D8P8C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1850246:LPB138 RS06725
gene id: 1850246:LPB138_RS06725
uniprot id: A0A1D8PBS4
names: Similarity
messages: Belongs to the CIA30 family.

1850246:LPB138 RS03025
gene id: 1850246:LPB138_RS03025
uniprot id: A0A1D8P566
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1850246:LPB138 RS07145
gene id: 1850246:LPB138_RS07145
uniprot id: A0A1D8P7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS11930
gene id: 1850246:LPB138_RS11930
uniprot id: A0A1D8PC25
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1850246:LPB138 RS07775
gene id: 1850246:LPB138_RS07775
uniprot id: A0A1D8P7Q6
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

1850246:LPB138 RS09655
gene id: 1850246:LPB138_RS09655
uniprot id: A0A1D8P8P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1850246:LPB138 RS07100
gene id: 1850246:LPB138_RS07100
uniprot id: A0A1D8P7B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1850246:LPB138 RS10135
gene id: 1850246:LPB138_RS10135
uniprot id: A0A1D8P8Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1850246:LPB138 RS02935
gene id: 1850246:LPB138_RS02935
uniprot id: A0A1D8PBQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1850246:LPB138 RS02590
gene id: 1850246:LPB138_RS02590
uniprot id: A0A1D8P505
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS00465
gene id: 1850246:LPB138_RS00465
uniprot id: A0A1D8P3U0
names: Similarity
messages: Belongs to the isochorismate synthase family.

1850246:LPB138 RS10565
gene id: 1850246:LPB138_RS10565
uniprot id: A0A1D8P948
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1850246:LPB138 RS12860
gene id: 1850246:LPB138_RS12860
uniprot id: A0A1D8PAB9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1850246:LPB138 RS12525
gene id: 1850246:LPB138_RS12525
uniprot id: A0A1D8PA55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1850246:LPB138 RS13065
gene id: 1850246:LPB138_RS13065
uniprot id: A0A1D8PAE6
names: Similarity
messages: Belongs to the SusD family.

1850246:LPB138 RS00035
gene id: 1850246:LPB138_RS00035
uniprot id: A0A1D8P3K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS10255
gene id: 1850246:LPB138_RS10255
uniprot id: A0A1D8P8X6
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1850246:LPB138 RS06940
gene id: 1850246:LPB138_RS06940
uniprot id: A0A1D8P787
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1850246:LPB138 RS12925
gene id: 1850246:LPB138_RS12925
uniprot id: A0A1D8PAF8
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1850246:LPB138 RS14300
gene id: 1850246:LPB138_RS14300
uniprot id: A0A1D8PB50
names: Similarity
messages: Belongs to the asparagine synthetase family.

1850246:LPB138 RS06015
gene id: 1850246:LPB138_RS06015
uniprot id: A0A1D8P6R8
names: Subunit
messages: Homodimer.

1850246:LPB138 RS07175
gene id: 1850246:LPB138_RS07175
uniprot id: A0A1D8P7F3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1850246:LPB138 RS10195
gene id: 1850246:LPB138_RS10195
uniprot id: A0A1D8P8W5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1850246:LPB138 RS13100
gene id: 1850246:LPB138_RS13100
uniprot id: A0A1D8PAJ1
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

1850246:LPB138 RS07485
gene id: 1850246:LPB138_RS07485
uniprot id: A0A1D8P7H1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1850246:LPB138 RS06060
gene id: 1850246:LPB138_RS06060
uniprot id: A0A1D8P6S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1850246:LPB138 RS10825
gene id: 1850246:LPB138_RS10825
uniprot id: A0A1D8P986
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1850246:LPB138 RS02825
gene id: 1850246:LPB138_RS02825
uniprot id: A0A1D8P525
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1850246:LPB138 RS14335
gene id: 1850246:LPB138_RS14335
uniprot id: A0A1D8PB31
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS02620
gene id: 1850246:LPB138_RS02620
uniprot id: A0A1D8P4X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1850246:LPB138 RS11725
gene id: 1850246:LPB138_RS11725
uniprot id: A0A1D8P9T6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1850246:LPB138 RS04160
gene id: 1850246:LPB138_RS04160
uniprot id: A0A1D8P5U4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1850246:LPB138 RS13340
gene id: 1850246:LPB138_RS13340
uniprot id: A0A1D8PAL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1850246:LPB138 RS04390
gene id: 1850246:LPB138_RS04390
uniprot id: A0A1D8P5V4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1850246:LPB138 RS14270
gene id: 1850246:LPB138_RS14270
uniprot id: A0A1D8PB45
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS12245
gene id: 1850246:LPB138_RS12245
uniprot id: A0A1D8PA59
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1850246:LPB138 RS04710
gene id: 1850246:LPB138_RS04710
uniprot id: A0A1D8P631
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1850246:LPB138 RS06985
gene id: 1850246:LPB138_RS06985
uniprot id: A0A1D8P790
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1850246:LPB138 RS05035
gene id: 1850246:LPB138_RS05035
uniprot id: A0A1D8P6B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1850246:LPB138 RS13445
gene id: 1850246:LPB138_RS13445
uniprot id: A0A1D8PAL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1850246:LPB138 RS09455
gene id: 1850246:LPB138_RS09455
uniprot id: A0A1D8P8I4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1850246:LPB138 RS04775
gene id: 1850246:LPB138_RS04775
uniprot id: A0A1D8P643
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1850246:LPB138 RS09210
gene id: 1850246:LPB138_RS09210
uniprot id: A0A1D8P8G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1850246:LPB138 RS09620
gene id: 1850246:LPB138_RS09620
uniprot id: A0A1D8P8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS01825
gene id: 1850246:LPB138_RS01825
uniprot id: A0A1D8P4L0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1850246:LPB138 RS09690
gene id: 1850246:LPB138_RS09690
uniprot id: A0A1D8P8L2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1850246:LPB138 RS03460
gene id: 1850246:LPB138_RS03460
uniprot id: A0A1D8P5E7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1850246:LPB138 RS04660
gene id: 1850246:LPB138_RS04660
uniprot id: A0A1D8P620
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1850246:LPB138 RS12480
gene id: 1850246:LPB138_RS12480
uniprot id: A0A1D8PA45
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1850246:LPB138 RS01750
gene id: 1850246:LPB138_RS01750
uniprot id: A0A1D8P4I9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS10990
gene id: 1850246:LPB138_RS10990
uniprot id: A0A1D8P9B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1850246:LPB138 RS12490
gene id: 1850246:LPB138_RS12490
uniprot id: A0A1D8PAA5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1850246:LPB138 RS04030
gene id: 1850246:LPB138_RS04030
uniprot id: A0A1D8P5N8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS05970
gene id: 1850246:LPB138_RS05970
uniprot id: A0A1D8P6Q2
names: Similarity
messages: Belongs to the RutC family.

1850246:LPB138 RS09590
gene id: 1850246:LPB138_RS09590
uniprot id: A0A1D8P8J7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1850246:LPB138 RS07460
gene id: 1850246:LPB138_RS07460
uniprot id: A0A1D8P7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1850246:LPB138 RS10865
gene id: 1850246:LPB138_RS10865
uniprot id: A0A1D8P9A0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1850246:LPB138 RS05325
gene id: 1850246:LPB138_RS05325
uniprot id: A0A1D8P6E1
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1850246:LPB138 RS01555
gene id: 1850246:LPB138_RS01555
uniprot id: A0A1D8P4D9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS01810
gene id: 1850246:LPB138_RS01810
uniprot id: A0A1D8PBM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1850246:LPB138 RS10635
gene id: 1850246:LPB138_RS10635
uniprot id: A0A1D8P967
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1850246:LPB138 RS12340
gene id: 1850246:LPB138_RS12340
uniprot id: A0A1D8P9Y3
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS03145
gene id: 1850246:LPB138_RS03145
uniprot id: A0A1D8P576
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1850246:LPB138 RS06825
gene id: 1850246:LPB138_RS06825
uniprot id: A0A1D8P769
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS00175
gene id: 1850246:LPB138_RS00175
uniprot id: A0A1D8P3U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1850246:LPB138 RS03285
gene id: 1850246:LPB138_RS03285
uniprot id: A0A1D8P5D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850246:LPB138 RS14830
gene id: 1850246:LPB138_RS14830
uniprot id: A0A1D8PBJ7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1850246:LPB138 RS08165
gene id: 1850246:LPB138_RS08165
uniprot id: A0A1D8P7Z4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1850246:LPB138 RS08090
gene id: 1850246:LPB138_RS08090
uniprot id: A0A1D8P7T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS12815
gene id: 1850246:LPB138_RS12815
uniprot id: A0A1D8PBZ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

1850246:LPB138 RS05500
gene id: 1850246:LPB138_RS05500
uniprot id: A0A1D8P6K4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850246:LPB138 RS06945
gene id: 1850246:LPB138_RS06945
uniprot id: A0A1D8P7A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1850246:LPB138 RS13900
gene id: 1850246:LPB138_RS13900
uniprot id: A0A1D8PAZ1
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS13190
gene id: 1850246:LPB138_RS13190
uniprot id: A0A1D8PAG9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1850246:LPB138 RS08780
gene id: 1850246:LPB138_RS08780
uniprot id: A0A1D8P864
names: Similarity
messages: Belongs to the bacterial secretin family.

1850246:LPB138 RS07295
gene id: 1850246:LPB138_RS07295
uniprot id: A0A1D8P7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS09555
gene id: 1850246:LPB138_RS09555
uniprot id: A0A1D8P8L1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1850246:LPB138 RS12680
gene id: 1850246:LPB138_RS12680
uniprot id: A0A1D8PA82
names: Similarity
messages: Belongs to the universal stress protein A family.

1850246:LPB138 RS06535
gene id: 1850246:LPB138_RS06535
uniprot id: A0A1D8P707
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1850246:LPB138 RS14540
gene id: 1850246:LPB138_RS14540
uniprot id: A0A1D8PB76
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1850246:LPB138 RS15145
gene id: 1850246:LPB138_RS15145
uniprot id: A0A1D8PBJ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1850246:LPB138 RS00140
gene id: 1850246:LPB138_RS00140
uniprot id: A0A1D8P3M1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS14465
gene id: 1850246:LPB138_RS14465
uniprot id: A0A1D8PB58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1850246:LPB138 RS05825
gene id: 1850246:LPB138_RS05825
uniprot id: A0A1D8P6N1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1850246:LPB138 RS14865
gene id: 1850246:LPB138_RS14865
uniprot id: A0A1D8PBD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1850246:LPB138 RS11225
gene id: 1850246:LPB138_RS11225
uniprot id: A0A1D8P9H2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850246:LPB138 RS10890
gene id: 1850246:LPB138_RS10890
uniprot id: A0A1D8P9A6
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1850246:LPB138 RS02515
gene id: 1850246:LPB138_RS02515
uniprot id: A0A1D8P4V0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1850246:LPB138 RS13730
gene id: 1850246:LPB138_RS13730
uniprot id: A0A1D8PAR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1850246:LPB138 RS09050
gene id: 1850246:LPB138_RS09050
uniprot id: A0A1D8P8B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1850246:LPB138 RS14425
gene id: 1850246:LPB138_RS14425
uniprot id: A0A1D8PB42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1850246:LPB138 RS10045
gene id: 1850246:LPB138_RS10045
uniprot id: A0A1D8P8V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1850246:LPB138 RS06005
gene id: 1850246:LPB138_RS06005
uniprot id: A0A1D8P6T8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1850246:LPB138 RS06935
gene id: 1850246:LPB138_RS06935
uniprot id: A0A1D8PBW8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1850246:LPB138 RS14680
gene id: 1850246:LPB138_RS14680
uniprot id: A0A1D8PBB0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS10145
gene id: 1850246:LPB138_RS10145
uniprot id: A0A1D8P8V2
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1850246:LPB138 RS00530
gene id: 1850246:LPB138_RS00530
uniprot id: A0A1D8P3U4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1850246:LPB138 RS06710
gene id: 1850246:LPB138_RS06710
uniprot id: A0A1D8PBT6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1850246:LPB138 RS09845
gene id: 1850246:LPB138_RS09845
uniprot id: A0A1D8P8R1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS03115
gene id: 1850246:LPB138_RS03115
uniprot id: A0A1D8P5C3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1850246:LPB138 RS07910
gene id: 1850246:LPB138_RS07910
uniprot id: A0A1D8P7Q7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS05110
gene id: 1850246:LPB138_RS05110
uniprot id: A0A1D8P6B7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1850246:LPB138 RS10140
gene id: 1850246:LPB138_RS10140
uniprot id: A0A1D8P8Z6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1850246:LPB138 RS09440
gene id: 1850246:LPB138_RS09440
uniprot id: A0A1D8P8I5
names: Similarity
messages: Belongs to the MoaD family.

1850246:LPB138 RS02870
gene id: 1850246:LPB138_RS02870
uniprot id: A0A1D8P531
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1850246:LPB138 RS02650
gene id: 1850246:LPB138_RS02650
uniprot id: A0A1D8P512
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1850246:LPB138 RS03730
gene id: 1850246:LPB138_RS03730
uniprot id: A0A1D8P5J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS09375
gene id: 1850246:LPB138_RS09375
uniprot id: A0A1D8P8G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1850246:LPB138 RS04870
gene id: 1850246:LPB138_RS04870
uniprot id: A0A1D8P657
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS10390
gene id: 1850246:LPB138_RS10390
uniprot id: A0A1D8PBW0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1850246:LPB138 RS07655
gene id: 1850246:LPB138_RS07655
uniprot id: A0A1D8P7M9
names: Similarity
messages: Belongs to the SusD family.

1850246:LPB138 RS14925
gene id: 1850246:LPB138_RS14925
uniprot id: A0A1D8PBE5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1850246:LPB138 RS02455
gene id: 1850246:LPB138_RS02455
uniprot id: A0A1D8P4W8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS08880
gene id: 1850246:LPB138_RS08880
uniprot id: A0A1D8P880
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1850246:LPB138 RS11920
gene id: 1850246:LPB138_RS11920
uniprot id: A0A1D8P9T0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1850246:LPB138 RS04295
gene id: 1850246:LPB138_RS04295
uniprot id: A0A1D8P5U9
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS06575
gene id: 1850246:LPB138_RS06575
uniprot id: A0A1D8P705
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1850246:LPB138 RS08005
gene id: 1850246:LPB138_RS08005
uniprot id: A0A1D8P7U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1850246:LPB138 RS09830
gene id: 1850246:LPB138_RS09830
uniprot id: A0A1D8P8U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1850246:LPB138 RS10555
gene id: 1850246:LPB138_RS10555
uniprot id: A0A1D8P937
names: Similarity
messages: Belongs to the peptidase S33 family.

1850246:LPB138 RS02050
gene id: 1850246:LPB138_RS02050
uniprot id: A0A1D8P4M9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1850246:LPB138 RS11770
gene id: 1850246:LPB138_RS11770
uniprot id: A0A1D8P9R1
names: Similarity
messages: Belongs to the UPF0102 family.

1850246:LPB138 RS13135
gene id: 1850246:LPB138_RS13135
uniprot id: A0A1D8PAH3
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1850246:LPB138 RS10270
gene id: 1850246:LPB138_RS10270
uniprot id: A0A1D8P8Y1
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1850246:LPB138 RS03785
gene id: 1850246:LPB138_RS03785
uniprot id: A0A1D8P5K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1850246:LPB138 RS14515
gene id: 1850246:LPB138_RS14515
uniprot id: A0A1D8PB62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1850246:LPB138 RS06620
gene id: 1850246:LPB138_RS06620
uniprot id: A0A1D8P728
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1850246:LPB138 RS13785
gene id: 1850246:LPB138_RS13785
uniprot id: A0A1D8PAV1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1850246:LPB138 RS04130
gene id: 1850246:LPB138_RS04130
uniprot id: A0A1D8P5Q3
names: Similarity
messages: Belongs to the Dps family.

1850246:LPB138 RS08785
gene id: 1850246:LPB138_RS08785
uniprot id: A0A1D8P869
names: Similarity
messages: Belongs to the GSP E family.

1850246:LPB138 RS01330
gene id: 1850246:LPB138_RS01330
uniprot id: A0A1D8P4C3
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS10700
gene id: 1850246:LPB138_RS10700
uniprot id: A0A1D8P973
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1850246:LPB138 RS04890
gene id: 1850246:LPB138_RS04890
uniprot id: A0A1D8P662
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850246:LPB138 RS12105
gene id: 1850246:LPB138_RS12105
uniprot id: A0A1D8PA24
names: Similarity
messages: Belongs to the YicC/YloC family.

1850246:LPB138 RS15055
gene id: 1850246:LPB138_RS15055
uniprot id: A0A1D8PBI5
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS11625
gene id: 1850246:LPB138_RS11625
uniprot id: A0A1D8P9M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1850246:LPB138 RS13305
gene id: 1850246:LPB138_RS13305
uniprot id: A0A1D8PAM9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1850246:LPB138 RS11755
gene id: 1850246:LPB138_RS11755
uniprot id: A0A1D8P9Z1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1850246:LPB138 RS10450
gene id: 1850246:LPB138_RS10450
uniprot id: A0A1D8P929
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1850246:LPB138 RS14370
gene id: 1850246:LPB138_RS14370
uniprot id: A0A1D8PB64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS05290
gene id: 1850246:LPB138_RS05290
uniprot id: A0A1D8P6C9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1850246:LPB138 RS00385
gene id: 1850246:LPB138_RS00385
uniprot id: A0A1D8P3T1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1850246:LPB138 RS06630
gene id: 1850246:LPB138_RS06630
uniprot id: A0A1D8P717
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1850246:LPB138 RS02930
gene id: 1850246:LPB138_RS02930
uniprot id: A0A1D8P540
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS06035
gene id: 1850246:LPB138_RS06035
uniprot id: A0A1D8PBW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1850246:LPB138 RS04945
gene id: 1850246:LPB138_RS04945
uniprot id: A0A1D8P669
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1850246:LPB138 RS11230
gene id: 1850246:LPB138_RS11230
uniprot id: A0A1D8P9G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1850246:LPB138 RS02940
gene id: 1850246:LPB138_RS02940
uniprot id: A0A1D8P552
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1850246:LPB138 RS11020
gene id: 1850246:LPB138_RS11020
uniprot id: A0A1D8P9C8
names: Similarity
messages: Belongs to the GARS family.

1850246:LPB138 RS01565
gene id: 1850246:LPB138_RS01565
uniprot id: A0A1D8P4K6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS07640
gene id: 1850246:LPB138_RS07640
uniprot id: A0A1D8P7N2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1850246:LPB138 RS08245
gene id: 1850246:LPB138_RS08245
uniprot id: A0A1D8P7W8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1850246:LPB138 RS04745
gene id: 1850246:LPB138_RS04745
uniprot id: A0A1D8P672
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS09705
gene id: 1850246:LPB138_RS09705
uniprot id: A0A1D8P8P4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1850246:LPB138 RS04935
gene id: 1850246:LPB138_RS04935
uniprot id: A0A1D8P689
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1850246:LPB138 RS00565
gene id: 1850246:LPB138_RS00565
uniprot id: A0A1D8P3V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS05800
gene id: 1850246:LPB138_RS05800
uniprot id: A0A1D8P6M5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1850246:LPB138 RS13175
gene id: 1850246:LPB138_RS13175
uniprot id: A0A1D8PAG0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1850246:LPB138 RS11715
gene id: 1850246:LPB138_RS11715
uniprot id: A0A1D8P9P1
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS09520
gene id: 1850246:LPB138_RS09520
uniprot id: A0A1D8P8J8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1850246:LPB138 RS09865
gene id: 1850246:LPB138_RS09865
uniprot id: A0A1D8P8R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1850246:LPB138 RS09020
gene id: 1850246:LPB138_RS09020
uniprot id: A0A1D8P8A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1850246:LPB138 RS14900
gene id: 1850246:LPB138_RS14900
uniprot id: A0A1D8PBD9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS14360
gene id: 1850246:LPB138_RS14360
uniprot id: A0A1D8PB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS05190
gene id: 1850246:LPB138_RS05190
uniprot id: A0A1D8P6A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS14275
gene id: 1850246:LPB138_RS14275
uniprot id: A0A1D8PB16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS01690
gene id: 1850246:LPB138_RS01690
uniprot id: A0A1D8P4I0
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS04705
gene id: 1850246:LPB138_RS04705
uniprot id: A0A1D8P624
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1850246:LPB138 RS00235
gene id: 1850246:LPB138_RS00235
uniprot id: A0A1D8P3V8
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS01545
gene id: 1850246:LPB138_RS01545
uniprot id: A0A1D8P4F4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1850246:LPB138 RS11415
gene id: 1850246:LPB138_RS11415
uniprot id: A0A1D8P9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1850246:LPB138 RS05340
gene id: 1850246:LPB138_RS05340
uniprot id: A0A1D8P6E9
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1850246:LPB138 RS11125
gene id: 1850246:LPB138_RS11125
uniprot id: A0A1D8P9G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1850246:LPB138 RS02340
gene id: 1850246:LPB138_RS02340
uniprot id: A0A1D8P4V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1850246:LPB138 RS09220
gene id: 1850246:LPB138_RS09220
uniprot id: A0A1D8P8F0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850246:LPB138 RS03125
gene id: 1850246:LPB138_RS03125
uniprot id: A0A1D8P575
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1850246:LPB138 RS11910
gene id: 1850246:LPB138_RS11910
uniprot id: A0A1D8P9R7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1850246:LPB138 RS02845
gene id: 1850246:LPB138_RS02845
uniprot id: A0A1D8P518
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1850246:LPB138 RS09125
gene id: 1850246:LPB138_RS09125
uniprot id: A0A1D8P8D1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1850246:LPB138 RS01465
gene id: 1850246:LPB138_RS01465
uniprot id: A0A1D8P4B9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1850246:LPB138 RS06905
gene id: 1850246:LPB138_RS06905
uniprot id: A0A1D8P7A2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1850246:LPB138 RS10570
gene id: 1850246:LPB138_RS10570
uniprot id: A0A1D8P954
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS12345
gene id: 1850246:LPB138_RS12345
uniprot id: A0A1D8PA11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1850246:LPB138 RS11430
gene id: 1850246:LPB138_RS11430
uniprot id: A0A1D8P9J8
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS04605
gene id: 1850246:LPB138_RS04605
uniprot id: A0A1D8P633
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS14055
gene id: 1850246:LPB138_RS14055
uniprot id: A0A1D8PAX6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1850246:LPB138 RS13555
gene id: 1850246:LPB138_RS13555
uniprot id: A0A1D8PAN1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1850246:LPB138 RS05580
gene id: 1850246:LPB138_RS05580
uniprot id: A0A1D8P6K3
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS08075
gene id: 1850246:LPB138_RS08075
uniprot id: A0A1D8P7T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

1850246:LPB138 RS10165
gene id: 1850246:LPB138_RS10165
uniprot id: A0A1D8P8V8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1850246:LPB138 RS04360
gene id: 1850246:LPB138_RS04360
uniprot id: A0A1D8P5Y3
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS11445
gene id: 1850246:LPB138_RS11445
uniprot id: A0A1D8P9J2
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS06075
gene id: 1850246:LPB138_RS06075
uniprot id: A0A1D8P6R9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1850246:LPB138 RS04400
gene id: 1850246:LPB138_RS04400
uniprot id: A0A1D8P5X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1850246:LPB138 RS09625
gene id: 1850246:LPB138_RS09625
uniprot id: A0A1D8P8L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS11915
gene id: 1850246:LPB138_RS11915
uniprot id: A0A1D8P9V4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1850246:LPB138 RS14880
gene id: 1850246:LPB138_RS14880
uniprot id: A0A1D8PBE3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1850246:LPB138 RS02920
gene id: 1850246:LPB138_RS02920
uniprot id: A0A1D8P570
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1850246:LPB138 RS09665
gene id: 1850246:LPB138_RS09665
uniprot id: A0A1D8P8M2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1850246:LPB138 RS05930
gene id: 1850246:LPB138_RS05930
uniprot id: A0A1D8P6Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1850246:LPB138 RS11235
gene id: 1850246:LPB138_RS11235
uniprot id: A0A1D8P9H8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS09380
gene id: 1850246:LPB138_RS09380
uniprot id: A0A1D8P8I6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1850246:LPB138 RS00475
gene id: 1850246:LPB138_RS00475
uniprot id: A0A1D8P409
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1850246:LPB138 RS07035
gene id: 1850246:LPB138_RS07035
uniprot id: A0A1D8P783
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1850246:LPB138 RS07155
gene id: 1850246:LPB138_RS07155
uniprot id: A0A1D8P7C1
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1850246:LPB138 RS13510
gene id: 1850246:LPB138_RS13510
uniprot id: A0A1D8PAR3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS01510
gene id: 1850246:LPB138_RS01510
uniprot id: A0A1D8P4K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1850246:LPB138 RS14490
gene id: 1850246:LPB138_RS14490
uniprot id: A0A1D8PB72
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1850246:LPB138 RS12035
gene id: 1850246:LPB138_RS12035
uniprot id: A0A1D8P9X0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS04825
gene id: 1850246:LPB138_RS04825
uniprot id: A0A1D8PBS0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1850246:LPB138 RS10375
gene id: 1850246:LPB138_RS10375
uniprot id: A0A1D8P910
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1850246:LPB138 RS04385
gene id: 1850246:LPB138_RS04385
uniprot id: A0A1D8P608
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1850246:LPB138 RS11880
gene id: 1850246:LPB138_RS11880
uniprot id: A0A1D8P9Y8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1850246:LPB138 RS01840
gene id: 1850246:LPB138_RS01840
uniprot id: A0A1D8P4L4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1850246:LPB138 RS12515
gene id: 1850246:LPB138_RS12515
uniprot id: A0A1D8PA32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1850246:LPB138 RS11015
gene id: 1850246:LPB138_RS11015
uniprot id: A0A1D8P9C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1850246:LPB138 RS07095
gene id: 1850246:LPB138_RS07095
uniprot id: A0A1D8P7A9
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1850246:LPB138 RS04980
gene id: 1850246:LPB138_RS04980
uniprot id: A0A1D8P670
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1850246:LPB138 RS12375
gene id: 1850246:LPB138_RS12375
uniprot id: A0A1D8PA77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

1850246:LPB138 RS11455
gene id: 1850246:LPB138_RS11455
uniprot id: A0A1D8P9K5
names: Similarity
messages: Belongs to the universal stress protein A family.

1850246:LPB138 RS13410
gene id: 1850246:LPB138_RS13410
uniprot id: A0A1D8PAN6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS11885
gene id: 1850246:LPB138_RS11885
uniprot id: A0A1D8P9R9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1850246:LPB138 RS12825
gene id: 1850246:LPB138_RS12825
uniprot id: A0A1D8PA94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1850246:LPB138 RS15100
gene id: 1850246:LPB138_RS15100
uniprot id: A0A1D8PBJ4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1850246:LPB138 RS08130
gene id: 1850246:LPB138_RS08130
uniprot id: A0A1D8P7V6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1850246:LPB138 RS00800
gene id: 1850246:LPB138_RS00800
uniprot id: A0A1D8P441
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1850246:LPB138 RS01665
gene id: 1850246:LPB138_RS01665
uniprot id: A0A1D8P4F0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850246:LPB138 RS05225
gene id: 1850246:LPB138_RS05225
uniprot id: A0A1D8P6F8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850246:LPB138 RS02065
gene id: 1850246:LPB138_RS02065
uniprot id: A0A1D8P4Q0
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS14725
gene id: 1850246:LPB138_RS14725
uniprot id: A0A1D8PBI2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS09605
gene id: 1850246:LPB138_RS09605
uniprot id: A0A1D8P8N3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1850246:LPB138 RS14590
gene id: 1850246:LPB138_RS14590
uniprot id: A0A1D8PB83
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS05170
gene id: 1850246:LPB138_RS05170
uniprot id: A0A1D8P6D7
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS15195
gene id: 1850246:LPB138_RS15195
uniprot id: A0A1D8PBR7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1850246:LPB138 RS12370
gene id: 1850246:LPB138_RS12370
uniprot id: A0A1D8PA44
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1850246:LPB138 RS04595
gene id: 1850246:LPB138_RS04595
uniprot id: A0A1D8P613
names: Similarity
messages: Belongs to the UPF0047 family.

1850246:LPB138 RS05495
gene id: 1850246:LPB138_RS05495
uniprot id: A0A1D8P6H1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1850246:LPB138 RS10910
gene id: 1850246:LPB138_RS10910
uniprot id: A0A1D8P9B2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS12220
gene id: 1850246:LPB138_RS12220
uniprot id: A0A1D8PA52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1850246:LPB138 RS13195
gene id: 1850246:LPB138_RS13195
uniprot id: A0A1D8PAE9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS14480
gene id: 1850246:LPB138_RS14480
uniprot id: A0A1D8PB71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1850246:LPB138 RS03920
gene id: 1850246:LPB138_RS03920
uniprot id: A0A1D8P5Q7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850246:LPB138 RS12690
gene id: 1850246:LPB138_RS12690
uniprot id: A0A1D8PA78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1850246:LPB138 RS06645
gene id: 1850246:LPB138_RS06645
uniprot id: A0A1D8P715
names: Similarity
messages: Belongs to the glutamine synthetase family.

1850246:LPB138 RS06960
gene id: 1850246:LPB138_RS06960
uniprot id: A0A1D8P773
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1850246:LPB138 RS04320
gene id: 1850246:LPB138_RS04320
uniprot id: A0A1D8P5W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS02370
gene id: 1850246:LPB138_RS02370
uniprot id: A0A1D8P501
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS05775
gene id: 1850246:LPB138_RS05775
uniprot id: A0A1D8P6M0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1850246:LPB138 RS13700
gene id: 1850246:LPB138_RS13700
uniprot id: A0A1D8PAQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1850246:LPB138 RS09710
gene id: 1850246:LPB138_RS09710
uniprot id: A0A1D8P8P5
names: Similarity
messages: Belongs to the peptidase S24 family.

1850246:LPB138 RS12935
gene id: 1850246:LPB138_RS12935
uniprot id: A0A1D8PAB6
names: Similarity
messages: Belongs to the SusD family.

1850246:LPB138 RS13705
gene id: 1850246:LPB138_RS13705
uniprot id: A0A1D8PAQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1850246:LPB138 RS06250
gene id: 1850246:LPB138_RS06250
uniprot id: A0A1D8P6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS10580
gene id: 1850246:LPB138_RS10580
uniprot id: A0A1D8P950
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1850246:LPB138 RS02315
gene id: 1850246:LPB138_RS02315
uniprot id: A0A1D8P4Z1
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1850246:LPB138 RS03635
gene id: 1850246:LPB138_RS03635
uniprot id: A0A1D8P5I3
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS07120
gene id: 1850246:LPB138_RS07120
uniprot id: A0A1D8P7E4
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1850246:LPB138 RS14545
gene id: 1850246:LPB138_RS14545
uniprot id: A0A1D8PBA0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1850246:LPB138 RS02980
gene id: 1850246:LPB138_RS02980
uniprot id: A0A1D8P582
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1850246:LPB138 RS01590
gene id: 1850246:LPB138_RS01590
uniprot id: A0A1D8P4H8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1850246:LPB138 RS11735
gene id: 1850246:LPB138_RS11735
uniprot id: A0A1D8P9P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1850246:LPB138 RS14525
gene id: 1850246:LPB138_RS14525
uniprot id: A0A1D8PB70
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1850246:LPB138 RS06080
gene id: 1850246:LPB138_RS06080
uniprot id: A0A1D8P6S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850246:LPB138 RS07000
gene id: 1850246:LPB138_RS07000
uniprot id: A0A1D8P777
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1850246:LPB138 RS06915
gene id: 1850246:LPB138_RS06915
uniprot id: A0A1D8P776
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS10530
gene id: 1850246:LPB138_RS10530
uniprot id: A0A1D8P945
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850246:LPB138 RS02585
gene id: 1850246:LPB138_RS02585
uniprot id: A0A1D8P4Y0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1850246:LPB138 RS09575
gene id: 1850246:LPB138_RS09575
uniprot id: A0A1D8P8K6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1850246:LPB138 RS05345
gene id: 1850246:LPB138_RS05345
uniprot id: A0A1D8P6F9
names: Similarity
messages: Belongs to the SusD family.

1850246:LPB138 RS03720
gene id: 1850246:LPB138_RS03720
uniprot id: A0A1D8P5J9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1850246:LPB138 RS14555
gene id: 1850246:LPB138_RS14555
uniprot id: A0A1D8PB88
names: Similarity
messages: Belongs to the citrate synthase family.

1850246:LPB138 RS12780
gene id: 1850246:LPB138_RS12780
uniprot id: A0A1D8PAC1
names: Similarity
messages: Belongs to the DEAD box helicase family.

1850246:LPB138 RS01440
gene id: 1850246:LPB138_RS01440
uniprot id: A0A1D8P4C5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1850246:LPB138 RS12440
gene id: 1850246:LPB138_RS12440
uniprot id: A0A1D8PA02
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850246:LPB138 RS03715
gene id: 1850246:LPB138_RS03715
uniprot id: A0A1D8P5J3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1850246:LPB138 RS05045
gene id: 1850246:LPB138_RS05045
uniprot id: A0A1D8P692
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS10515
gene id: 1850246:LPB138_RS10515
uniprot id: A0A1D8P944
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1850246:LPB138 RS11900
gene id: 1850246:LPB138_RS11900
uniprot id: A0A1D8P9R5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1850246:LPB138 RS07005
gene id: 1850246:LPB138_RS07005
uniprot id: A0A1D8P7A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS05230
gene id: 1850246:LPB138_RS05230
uniprot id: A0A1D8P6C8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850246:LPB138 RS14035
gene id: 1850246:LPB138_RS14035
uniprot id: A0A1D8PC09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1850246:LPB138 RS02835
gene id: 1850246:LPB138_RS02835
uniprot id: A0A1D8P526
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS13685
gene id: 1850246:LPB138_RS13685
uniprot id: A0A1D8PAT9
names: Similarity
messages: Belongs to the Lgt family.

1850246:LPB138 RS08500
gene id: 1850246:LPB138_RS08500
uniprot id: A0A1D8P819
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1850246:LPB138 RS07475
gene id: 1850246:LPB138_RS07475
uniprot id: A0A1D8P7G5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1850246:LPB138 RS13935
gene id: 1850246:LPB138_RS13935
uniprot id: A0A1D8PAW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1850246:LPB138 RS11590
gene id: 1850246:LPB138_RS11590
uniprot id: A0A1D8P9M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

1850246:LPB138 RS12775
gene id: 1850246:LPB138_RS12775
uniprot id: A0A1D8PA92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS07620
gene id: 1850246:LPB138_RS07620
uniprot id: A0A1D8P7K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1850246:LPB138 RS14475
gene id: 1850246:LPB138_RS14475
uniprot id: A0A1D8PB59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1850246:LPB138 RS09325
gene id: 1850246:LPB138_RS09325
uniprot id: A0A1D8P8F9
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS11745
gene id: 1850246:LPB138_RS11745
uniprot id: A0A1D8P9N3
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS15045
gene id: 1850246:LPB138_RS15045
uniprot id: A0A1D8PBI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1850246:LPB138 RS03170
gene id: 1850246:LPB138_RS03170
uniprot id: A0A1D8P593
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1850246:LPB138 RS02490
gene id: 1850246:LPB138_RS02490
uniprot id: A0A1D8P4Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1850246:LPB138 RS00280
gene id: 1850246:LPB138_RS00280
uniprot id: A0A1D8P3P0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1850246:LPB138 RS13110
gene id: 1850246:LPB138_RS13110
uniprot id: A0A1D8PAG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS12740
gene id: 1850246:LPB138_RS12740
uniprot id: A0A1D8PA91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1850246:LPB138 RS08055
gene id: 1850246:LPB138_RS08055
uniprot id: A0A1D8P7T9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1850246:LPB138 RS06195
gene id: 1850246:LPB138_RS06195
uniprot id: A0A1D8P6U6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1850246:LPB138 RS14455
gene id: 1850246:LPB138_RS14455
uniprot id: A0A1D8PB75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1850246:LPB138 RS12310
gene id: 1850246:LPB138_RS12310
uniprot id: A0A1D8PA28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1850246:LPB138 RS06110
gene id: 1850246:LPB138_RS06110
uniprot id: A0A1D8P6T6
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1850246:LPB138 RS13905
gene id: 1850246:LPB138_RS13905
uniprot id: A0A1D8PAU6
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1850246:LPB138 RS11610
gene id: 1850246:LPB138_RS11610
uniprot id: A0A1D8PC15
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1850246:LPB138 RS13865
gene id: 1850246:LPB138_RS13865
uniprot id: A0A1D8PAU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1850246:LPB138 RS00365
gene id: 1850246:LPB138_RS00365
uniprot id: A0A1D8P3R5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1850246:LPB138 RS04040
gene id: 1850246:LPB138_RS04040
uniprot id: A0A1D8P5T0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1850246:LPB138 RS05265
gene id: 1850246:LPB138_RS05265
uniprot id: A0A1D8P6C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1850246:LPB138 RS06955
gene id: 1850246:LPB138_RS06955
uniprot id: A0A1D8P799
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS07580
gene id: 1850246:LPB138_RS07580
uniprot id: A0A1D8P7J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1850246:LPB138 RS12315
gene id: 1850246:LPB138_RS12315
uniprot id: A0A1D8PA09
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1850246:LPB138 RS00005
gene id: 1850246:LPB138_RS00005
uniprot id: A0A1D8P3S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1850246:LPB138 RS09870
gene id: 1850246:LPB138_RS09870
uniprot id: A0A1D8P8T2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1850246:LPB138 RS13315
gene id: 1850246:LPB138_RS13315
uniprot id: A0A1D8PAK7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1850246:LPB138 RS06835
gene id: 1850246:LPB138_RS06835
uniprot id: A0A1D8P756
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1850246:LPB138 RS07875
gene id: 1850246:LPB138_RS07875
uniprot id: A0A1D8P7Q3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1850246:LPB138 RS12305
gene id: 1850246:LPB138_RS12305
uniprot id: A0A1D8P9Z0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1850246:LPB138 RS13630
gene id: 1850246:LPB138_RS13630
uniprot id: A0A1D8PAS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1850246:LPB138 RS08985
gene id: 1850246:LPB138_RS08985
uniprot id: A0A1D8P8E0
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1850246:LPB138 RS11890
gene id: 1850246:LPB138_RS11890
uniprot id: A0A1D8P9T4
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS04020
gene id: 1850246:LPB138_RS04020
uniprot id: A0A1D8P5S2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS09825
gene id: 1850246:LPB138_RS09825
uniprot id: A0A1D8P8Q1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1850246:LPB138 RS04280
gene id: 1850246:LPB138_RS04280
uniprot id: A0A1D8P5T6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1850246:LPB138 RS10885
gene id: 1850246:LPB138_RS10885
uniprot id: A0A1D8P9A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1850246:LPB138 RS09715
gene id: 1850246:LPB138_RS09715
uniprot id: A0A1D8P8P9
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1850246:LPB138 RS00155
gene id: 1850246:LPB138_RS00155
uniprot id: A0A1D8P3N0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1850246:LPB138 RS10655
gene id: 1850246:LPB138_RS10655
uniprot id: A0A1D8P966
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1850246:LPB138 RS03780
gene id: 1850246:LPB138_RS03780
uniprot id: A0A1D8P5K1
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1850246:LPB138 RS13335
gene id: 1850246:LPB138_RS13335
uniprot id: A0A1D8PAN7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1850246:LPB138 RS13605
gene id: 1850246:LPB138_RS13605
uniprot id: A0A1D8PAS0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1850246:LPB138 RS14495
gene id: 1850246:LPB138_RS14495
uniprot id: A0A1D8PB82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1850246:LPB138 RS14295
gene id: 1850246:LPB138_RS14295
uniprot id: A0A1D8PB36
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS02990
gene id: 1850246:LPB138_RS02990
uniprot id: A0A1D8P554
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1850246:LPB138 RS13320
gene id: 1850246:LPB138_RS13320
uniprot id: A0A1D8PAI3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1850246:LPB138 RS12565
gene id: 1850246:LPB138_RS12565
uniprot id: A0A1D8PA53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1850246:LPB138 RS09250
gene id: 1850246:LPB138_RS09250
uniprot id: A0A1D8P8G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

1850246:LPB138 RS03725
gene id: 1850246:LPB138_RS03725
uniprot id: A0A1D8P5L6
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1850246:LPB138 RS02245
gene id: 1850246:LPB138_RS02245
uniprot id: A0A1D8P4P8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1850246:LPB138 RS09600
gene id: 1850246:LPB138_RS09600
uniprot id: A0A1D8P8N2
names: Similarity
messages: Belongs to the DtxR/MntR family.

1850246:LPB138 RS12160
gene id: 1850246:LPB138_RS12160
uniprot id: A0A1D8PA36
names: Similarity
messages: Belongs to the ArsC family.

1850246:LPB138 RS09070
gene id: 1850246:LPB138_RS09070
uniprot id: A0A1D8P8B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1850246:LPB138 RS00025
gene id: 1850246:LPB138_RS00025
uniprot id: A0A1D8P3J1
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1850246:LPB138 RS14225
gene id: 1850246:LPB138_RS14225
uniprot id: A0A1D8PB11
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

1850246:LPB138 RS10630
gene id: 1850246:LPB138_RS10630
uniprot id: A0A1D8P960
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS06485
gene id: 1850246:LPB138_RS06485
uniprot id: A0A1D8P712
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS10080
gene id: 1850246:LPB138_RS10080
uniprot id: A0A1D8P8X8
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS00335
gene id: 1850246:LPB138_RS00335
uniprot id: A0A1D8P3X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1850246:LPB138 RS08915
gene id: 1850246:LPB138_RS08915
uniprot id: A0A1D8P896
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1850246:LPB138 RS04430
gene id: 1850246:LPB138_RS04430
uniprot id: A0A1D8P5X8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1850246:LPB138 RS04590
gene id: 1850246:LPB138_RS04590
uniprot id: A0A1D8P604
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS04100
gene id: 1850246:LPB138_RS04100
uniprot id: A0A1D8P5P4
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS06205
gene id: 1850246:LPB138_RS06205
uniprot id: A0A1D8P6U3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

1850246:LPB138 RS12615
gene id: 1850246:LPB138_RS12615
uniprot id: A0A1D8PA60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1850246:LPB138 RS06450
gene id: 1850246:LPB138_RS06450
uniprot id: A0A1D8P6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1850246:LPB138 RS12075
gene id: 1850246:LPB138_RS12075
uniprot id: A0A1D8P9W1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS02805
gene id: 1850246:LPB138_RS02805
uniprot id: A0A1D8P528
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS02695
gene id: 1850246:LPB138_RS02695
uniprot id: A0A1D8P4Z8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1850246:LPB138 RS11970
gene id: 1850246:LPB138_RS11970
uniprot id: A0A1D8P9V8
names: Similarity
messages: Belongs to the aspartokinase family.

1850246:LPB138 RS07755
gene id: 1850246:LPB138_RS07755
uniprot id: A0A1D8P7N3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1850246:LPB138 RS01140
gene id: 1850246:LPB138_RS01140
uniprot id: A0A1D8P4E3
names: Similarity
messages: Belongs to the RelE toxin family.

1850246:LPB138 RS11865
gene id: 1850246:LPB138_RS11865
uniprot id: A0A1D8P9V2
names: Similarity
messages: Belongs to the pyruvate kinase family.

1850246:LPB138 RS13615
gene id: 1850246:LPB138_RS13615
uniprot id: A0A1D8PAP1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1850246:LPB138 RS01420
gene id: 1850246:LPB138_RS01420
uniprot id: A0A1D8P4D3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1850246:LPB138 RS00440
gene id: 1850246:LPB138_RS00440
uniprot id: A0A1D8P3U1
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS03800
gene id: 1850246:LPB138_RS03800
uniprot id: A0A1D8P5K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1850246:LPB138 RS09560
gene id: 1850246:LPB138_RS09560
uniprot id: A0A1D8PBV5
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS10180
gene id: 1850246:LPB138_RS10180
uniprot id: A0A1D8P8W0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1850246:LPB138 RS00100
gene id: 1850246:LPB138_RS00100
uniprot id: A0A1D8P3N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1850246:LPB138 RS01745
gene id: 1850246:LPB138_RS01745
uniprot id: A0A1D8P4J2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS01315
gene id: 1850246:LPB138_RS01315
uniprot id: A0A1D8P489
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1850246:LPB138 RS15155
gene id: 1850246:LPB138_RS15155
uniprot id: A0A1D8PBJ0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1850246:LPB138 RS12945
gene id: 1850246:LPB138_RS12945
uniprot id: A0A1D8PAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 26 family.
messages: Secreted

1850246:LPB138 RS08320
gene id: 1850246:LPB138_RS08320
uniprot id: A0A1D8P7Z2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1850246:LPB138 RS10645
gene id: 1850246:LPB138_RS10645
uniprot id: A0A1D8P956
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1850246:LPB138 RS02250
gene id: 1850246:LPB138_RS02250
uniprot id: A0A1D8P4Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1850246:LPB138 RS05030
gene id: 1850246:LPB138_RS05030
uniprot id: A0A1D8P676
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS03905
gene id: 1850246:LPB138_RS03905
uniprot id: A0A1D8P5P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1850246:LPB138 RS08395
gene id: 1850246:LPB138_RS08395
uniprot id: A0A1D8P7Z1
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS02830
gene id: 1850246:LPB138_RS02830
uniprot id: A0A1D8P529
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1850246:LPB138 RS06145
gene id: 1850246:LPB138_RS06145
uniprot id: A0A1D8P6T5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS06780
gene id: 1850246:LPB138_RS06780
uniprot id: A0A1D8P742
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS00485
gene id: 1850246:LPB138_RS00485
uniprot id: A0A1D8P3U5
names: Similarity
messages: Belongs to the peptidase C1 family.

1850246:LPB138 RS10310
gene id: 1850246:LPB138_RS10310
uniprot id: A0A1D8P8Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1850246:LPB138 RS09540
gene id: 1850246:LPB138_RS09540
uniprot id: A0A1D8P8M3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1850246:LPB138 RS13105
gene id: 1850246:LPB138_RS13105
uniprot id: A0A1D8PAI0
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

1850246:LPB138 RS06640
gene id: 1850246:LPB138_RS06640
uniprot id: A0A1D8P720
names: Similarity
messages: Belongs to the glutamine synthetase family.

1850246:LPB138 RS03765
gene id: 1850246:LPB138_RS03765
uniprot id: A0A1D8P5L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1850246:LPB138 RS03120
gene id: 1850246:LPB138_RS03120
uniprot id: A0A1D8P581
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS01265
gene id: 1850246:LPB138_RS01265
uniprot id: A0A1D8P4A2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1850246:LPB138 RS05270
gene id: 1850246:LPB138_RS05270
uniprot id: A0A1D8P6C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1850246:LPB138 RS15105
gene id: 1850246:LPB138_RS15105
uniprot id: A0A1D8PBI3
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS15190
gene id: 1850246:LPB138_RS15190
uniprot id: A0A1D8PBL0
names: Similarity
messages: Belongs to the IMPACT family.

1850246:LPB138 RS05450
gene id: 1850246:LPB138_RS05450
uniprot id: A0A1D8P6F5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850246:LPB138 RS08750
gene id: 1850246:LPB138_RS08750
uniprot id: A0A1D8P862
names: Similarity
messages: Belongs to the HsdR family.

1850246:LPB138 RS13350
gene id: 1850246:LPB138_RS13350
uniprot id: A0A1D8PAJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1850246:LPB138 RS09775
gene id: 1850246:LPB138_RS09775
uniprot id: A0A1D8P8N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1850246:LPB138 RS12420
gene id: 1850246:LPB138_RS12420
uniprot id: A0A1D8PA49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

1850246:LPB138 RS08125
gene id: 1850246:LPB138_RS08125
uniprot id: A0A1D8P7U0
names: Similarity
messages: Belongs to the Skp family.

1850246:LPB138 RS05070
gene id: 1850246:LPB138_RS05070
uniprot id: A0A1D8P6A5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1850246:LPB138 RS14200
gene id: 1850246:LPB138_RS14200
uniprot id: A0A1D8PB14
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1850246:LPB138 RS06820
gene id: 1850246:LPB138_RS06820
uniprot id: A0A1D8P757
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1850246:LPB138 RS05715
gene id: 1850246:LPB138_RS05715
uniprot id: A0A1D8P6K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS03380
gene id: 1850246:LPB138_RS03380
uniprot id: A0A1D8P5G2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1850246:LPB138 RS06745
gene id: 1850246:LPB138_RS06745
uniprot id: A0A1D8P736
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1850246:LPB138 RS06785
gene id: 1850246:LPB138_RS06785
uniprot id: A0A1D8P752
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS11575
gene id: 1850246:LPB138_RS11575
uniprot id: A0A1D8P9L5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850246:LPB138 RS11560
gene id: 1850246:LPB138_RS11560
uniprot id: A0A1D8P9N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS00180
gene id: 1850246:LPB138_RS00180
uniprot id: A0A1D8P3P9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS07575
gene id: 1850246:LPB138_RS07575
uniprot id: A0A1D8P7J0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1850246:LPB138 RS15035
gene id: 1850246:LPB138_RS15035
uniprot id: A0A1D8PBP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1850246:LPB138 RS10775
gene id: 1850246:LPB138_RS10775
uniprot id: A0A1D8P992
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1850246:LPB138 RS13845
gene id: 1850246:LPB138_RS13845
uniprot id: A0A1D8PAX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1850246:LPB138 RS01095
gene id: 1850246:LPB138_RS01095
uniprot id: A0A1D8P442
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1850246:LPB138 RS04570
gene id: 1850246:LPB138_RS04570
uniprot id: A0A1D8P615
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1850246:LPB138 RS08365
gene id: 1850246:LPB138_RS08365
uniprot id: A0A1D8P7Z8
names: Similarity
messages: Belongs to the ArsC family.

1850246:LPB138 RS06460
gene id: 1850246:LPB138_RS06460
uniprot id: A0A1D8P709
names: Similarity
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.

1850246:LPB138 RS01335
gene id: 1850246:LPB138_RS01335
uniprot id: A0A1D8P4A3
names: Similarity
messages: Belongs to the NusB family.

1850246:LPB138 RS03505
gene id: 1850246:LPB138_RS03505
uniprot id: A0A1D8PBQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS13645
gene id: 1850246:LPB138_RS13645
uniprot id: A0A1D8PAQ1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1850246:LPB138 RS00360
gene id: 1850246:LPB138_RS00360
uniprot id: A0A1D8P3R9
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS01730
gene id: 1850246:LPB138_RS01730
uniprot id: A0A1D8P4H4
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

1850246:LPB138 RS11605
gene id: 1850246:LPB138_RS11605
uniprot id: A0A1D8P9S4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1850246:LPB138 RS06795
gene id: 1850246:LPB138_RS06795
uniprot id: A0A1D8P748
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1850246:LPB138 RS03130
gene id: 1850246:LPB138_RS03130
uniprot id: A0A1D8P5A1
names: Similarity
messages: Belongs to the aldose epimerase family.

1850246:LPB138 RS10540
gene id: 1850246:LPB138_RS10540
uniprot id: A0A1D8P941
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1850246:LPB138 RS06480
gene id: 1850246:LPB138_RS06480
uniprot id: A0A1D8P6Z3
names: Similarity
messages: Belongs to the P(II) protein family.

1850246:LPB138 RS07970
gene id: 1850246:LPB138_RS07970
uniprot id: A0A1D8P7R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1850246:LPB138 RS09645
gene id: 1850246:LPB138_RS09645
uniprot id: A0A1D8P8N9
names: Similarity
messages: Belongs to the SCO1/2 family.

1850246:LPB138 RS03575
gene id: 1850246:LPB138_RS03575
uniprot id: A0A1D8P5G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1850246:LPB138 RS12570
gene id: 1850246:LPB138_RS12570
uniprot id: A0A1D8PAA8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS13745
gene id: 1850246:LPB138_RS13745
uniprot id: A0A1D8PAT7
names: Similarity
messages: Belongs to the arginase family.

1850246:LPB138 RS06040
gene id: 1850246:LPB138_RS06040
uniprot id: A0A1D8P6T4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1850246:LPB138 RS04220
gene id: 1850246:LPB138_RS04220
uniprot id: A0A1D8P5V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1850246:LPB138 RS08740
gene id: 1850246:LPB138_RS08740
uniprot id: A0A1D8P857
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1850246:LPB138 RS10730
gene id: 1850246:LPB138_RS10730
uniprot id: A0A1D8P993
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1850246:LPB138 RS08210
gene id: 1850246:LPB138_RS08210
uniprot id: A0A1D8P7W3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1850246:LPB138 RS06635
gene id: 1850246:LPB138_RS06635
uniprot id: A0A1D8P726
names: Similarity
messages: Belongs to the AIR synthase family.

1850246:LPB138 RS14205
gene id: 1850246:LPB138_RS14205
uniprot id: A0A1D8PB13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1850246:LPB138 RS11520
gene id: 1850246:LPB138_RS11520
uniprot id: A0A1D8PBX5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850246:LPB138 RS13500
gene id: 1850246:LPB138_RS13500
uniprot id: A0A1D8PAM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1850246:LPB138 RS12325
gene id: 1850246:LPB138_RS12325
uniprot id: A0A1D8PA73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1850246:LPB138 RS03305
gene id: 1850246:LPB138_RS03305
uniprot id: A0A1D8P5B1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1850246:LPB138 RS07735
gene id: 1850246:LPB138_RS07735
uniprot id: A0A1D8P7M6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1850246:LPB138 RS07705
gene id: 1850246:LPB138_RS07705
uniprot id: A0A1D8P7M7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1850246:LPB138 RS02230
gene id: 1850246:LPB138_RS02230
uniprot id: A0A1D8P4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1850246:LPB138 RS12735
gene id: 1850246:LPB138_RS12735
uniprot id: A0A1D8PAF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1850246:LPB138 RS09320
gene id: 1850246:LPB138_RS09320
uniprot id: A0A1D8P8G8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS13855
gene id: 1850246:LPB138_RS13855
uniprot id: A0A1D8PAT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1850246:LPB138 RS06470
gene id: 1850246:LPB138_RS06470
uniprot id: A0A1D8P703
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1850246:LPB138 RS07665
gene id: 1850246:LPB138_RS07665
uniprot id: A0A1D8P7K8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1850246:LPB138 RS00705
gene id: 1850246:LPB138_RS00705
uniprot id: A0A1D8P452
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1850246:LPB138 RS08050
gene id: 1850246:LPB138_RS08050
uniprot id: A0A1D8P7T0
names: Similarity
messages: Belongs to the NAD synthetase family.

1850246:LPB138 RS07570
gene id: 1850246:LPB138_RS07570
uniprot id: A0A1D8P7J6
names: Similarity
messages: Belongs to the GbsR family.

1850246:LPB138 RS08110
gene id: 1850246:LPB138_RS08110
uniprot id: A0A1D8P7W6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1850246:LPB138 RS09055
gene id: 1850246:LPB138_RS09055
uniprot id: A0A1D8P8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1850246:LPB138 RS00745
gene id: 1850246:LPB138_RS00745
uniprot id: A0A1D8P406
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS10780
gene id: 1850246:LPB138_RS10780
uniprot id: A0A1D8P987
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1850246:LPB138 RS09650
gene id: 1850246:LPB138_RS09650
uniprot id: A0A1D8P8P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1850246:LPB138 RS08905
gene id: 1850246:LPB138_RS08905
uniprot id: A0A1D8P885
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1850246:LPB138 RS11450
gene id: 1850246:LPB138_RS11450
uniprot id: A0A1D8P9K9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1850246:LPB138 RS03985
gene id: 1850246:LPB138_RS03985
uniprot id: A0A1D8P5M4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1850246:LPB138 RS06155
gene id: 1850246:LPB138_RS06155
uniprot id: A0A1D8P6S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1850246:LPB138 RS07105
gene id: 1850246:LPB138_RS07105
uniprot id: A0A1D8P798
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1850246:LPB138 RS10155
gene id: 1850246:LPB138_RS10155
uniprot id: A0A1D8P8W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS10330
gene id: 1850246:LPB138_RS10330
uniprot id: A0A1D8P912
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1850246:LPB138 RS10520
gene id: 1850246:LPB138_RS10520
uniprot id: A0A1D8PBX3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1850246:LPB138 RS06810
gene id: 1850246:LPB138_RS06810
uniprot id: A0A1D8P750
names: Similarity
messages: Belongs to the LOG family.

1850246:LPB138 RS01800
gene id: 1850246:LPB138_RS01800
uniprot id: A0A1D8PBM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1850246:LPB138 RS14445
gene id: 1850246:LPB138_RS14445
uniprot id: A0A1D8PB69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1850246:LPB138 RS07730
gene id: 1850246:LPB138_RS07730
uniprot id: A0A1D8P7M2
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS11775
gene id: 1850246:LPB138_RS11775
uniprot id: A0A1D8P9U5
names: Similarity
messages: Belongs to the peptidase S66 family.

1850246:LPB138 RS00805
gene id: 1850246:LPB138_RS00805
uniprot id: A0A1D8P416
names: Similarity
messages: Belongs to the Dps family.

1850246:LPB138 RS01975
gene id: 1850246:LPB138_RS01975
uniprot id: A0A1D8P4T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1850246:LPB138 RS01930
gene id: 1850246:LPB138_RS01930
uniprot id: A0A1D8P4K2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1850246:LPB138 RS11360
gene id: 1850246:LPB138_RS11360
uniprot id: A0A1D8P9I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1850246:LPB138 RS07700
gene id: 1850246:LPB138_RS07700
uniprot id: A0A1D8P7M3
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

1850246:LPB138 RS15065
gene id: 1850246:LPB138_RS15065
uniprot id: A0A1D8PBI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1850246:LPB138 RS08120
gene id: 1850246:LPB138_RS08120
uniprot id: A0A1D8P7V4
names: Similarity
messages: Belongs to the Skp family.

1850246:LPB138 RS03470
gene id: 1850246:LPB138_RS03470
uniprot id: A0A1D8P5F2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1850246:LPB138 RS11355
gene id: 1850246:LPB138_RS11355
uniprot id: A0A1D8P9J4
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS06700
gene id: 1850246:LPB138_RS06700
uniprot id: A0A1D8P739
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1850246:LPB138 RS14720
gene id: 1850246:LPB138_RS14720
uniprot id: A0A1D8PBA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1850246:LPB138 RS14805
gene id: 1850246:LPB138_RS14805
uniprot id: A0A1D8PBE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1850246:LPB138 RS00525
gene id: 1850246:LPB138_RS00525
uniprot id: A0A1D8P419
names: Similarity
messages: Belongs to the CinA family.

1850246:LPB138 RS04860
gene id: 1850246:LPB138_RS04860
uniprot id: A0A1D8P686
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1850246:LPB138 RS14450
gene id: 1850246:LPB138_RS14450
uniprot id: A0A1D8PB67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1850246:LPB138 RS09935
gene id: 1850246:LPB138_RS09935
uniprot id: A0A1D8P8T1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS06120
gene id: 1850246:LPB138_RS06120
uniprot id: A0A1D8P6T7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1850246:LPB138 RS10895
gene id: 1850246:LPB138_RS10895
uniprot id: A0A1D8P9D3
names: Similarity
messages: Belongs to the peptidase S41A family.

1850246:LPB138 RS01705
gene id: 1850246:LPB138_RS01705
uniprot id: A0A1D8P4I6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1850246:LPB138 RS12320
gene id: 1850246:LPB138_RS12320
uniprot id: A0A1D8PA35
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1850246:LPB138 RS12610
gene id: 1850246:LPB138_RS12610
uniprot id: A0A1D8PA54
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1850246:LPB138 RS11215
gene id: 1850246:LPB138_RS11215
uniprot id: A0A1D8P9F9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850246:LPB138 RS12685
gene id: 1850246:LPB138_RS12685
uniprot id: A0A1D8PA97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1850246:LPB138 RS05460
gene id: 1850246:LPB138_RS05460
uniprot id: A0A1D8P6I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1850246:LPB138 RS13230
gene id: 1850246:LPB138_RS13230
uniprot id: A0A1D8PAL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1850246:LPB138 RS11660
gene id: 1850246:LPB138_RS11660
uniprot id: A0A1D8P9N2
names: Similarity
messages: Belongs to the peptidase S41A family.

1850246:LPB138 RS12530
gene id: 1850246:LPB138_RS12530
uniprot id: A0A1D8PA74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1850246:LPB138 RS06225
gene id: 1850246:LPB138_RS06225
uniprot id: A0A1D8P6V5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1850246:LPB138 RS03615
gene id: 1850246:LPB138_RS03615
uniprot id: A0A1D8P5I2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS10695
gene id: 1850246:LPB138_RS10695
uniprot id: A0A1D8P975
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1850246:LPB138 RS00575
gene id: 1850246:LPB138_RS00575
uniprot id: A0A1D8P435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850246:LPB138 RS02335
gene id: 1850246:LPB138_RS02335
uniprot id: A0A1D8P4T8
names: Similarity
messages: Belongs to the MQO family.

1850246:LPB138 RS06085
gene id: 1850246:LPB138_RS06085
uniprot id: A0A1D8P6S1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS11815
gene id: 1850246:LPB138_RS11815
uniprot id: A0A1D8P9V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS05975
gene id: 1850246:LPB138_RS05975
uniprot id: A0A1D8P6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850246:LPB138 RS10535
gene id: 1850246:LPB138_RS10535
uniprot id: A0A1D8P942
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1850246:LPB138 RS12275
gene id: 1850246:LPB138_RS12275
uniprot id: A0A1D8PA04
names: Similarity
messages: Belongs to the RelE toxin family.

1850246:LPB138 RS04985
gene id: 1850246:LPB138_RS04985
uniprot id: A0A1D8P675
names: Similarity
messages: Belongs to the peptidase C40 family.

1850246:LPB138 RS02510
gene id: 1850246:LPB138_RS02510
uniprot id: A0A1D8P4W2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS03555
gene id: 1850246:LPB138_RS03555
uniprot id: A0A1D8P5G8
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1850246:LPB138 RS13395
gene id: 1850246:LPB138_RS13395
uniprot id: A0A1D8PAJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1850246:LPB138 RS04450
gene id: 1850246:LPB138_RS04450
uniprot id: A0A1D8P5Z7
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS08970
gene id: 1850246:LPB138_RS08970
uniprot id: A0A1D8P8A7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1850246:LPB138 RS14485
gene id: 1850246:LPB138_RS14485
uniprot id: A0A1D8PB65
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1850246:LPB138 RS10440
gene id: 1850246:LPB138_RS10440
uniprot id: A0A1D8P916
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1850246:LPB138 RS13960
gene id: 1850246:LPB138_RS13960
uniprot id: A0A1D8PAW7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1850246:LPB138 RS13995
gene id: 1850246:LPB138_RS13995
uniprot id: A0A1D8PAY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Heterotrimer of A, B and C subunits.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS00340
gene id: 1850246:LPB138_RS00340
uniprot id: A0A1D8P3V1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1850246:LPB138 RS06800
gene id: 1850246:LPB138_RS06800
uniprot id: A0A1D8P771
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS04190
gene id: 1850246:LPB138_RS04190
uniprot id: A0A1D8P5T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1850246:LPB138 RS01410
gene id: 1850246:LPB138_RS01410
uniprot id: A0A1D8P4B4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1850246:LPB138 RS10115
gene id: 1850246:LPB138_RS10115
uniprot id: A0A1D8P8V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS08000
gene id: 1850246:LPB138_RS08000
uniprot id: A0A1D8P7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1850246:LPB138 RS10095
gene id: 1850246:LPB138_RS10095
uniprot id: A0A1D8P8W2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1850246:LPB138 RS01460
gene id: 1850246:LPB138_RS01460
uniprot id: A0A1D8P4D6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1850246:LPB138 RS01655
gene id: 1850246:LPB138_RS01655
uniprot id: A0A1D8P4H5
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS05635
gene id: 1850246:LPB138_RS05635
uniprot id: A0A1D8P6K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1850246:LPB138 RS10760
gene id: 1850246:LPB138_RS10760
uniprot id: A0A1D8P984
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1850246:LPB138 RS09255
gene id: 1850246:LPB138_RS09255
uniprot id: A0A1D8P8F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS14280
gene id: 1850246:LPB138_RS14280
uniprot id: A0A1D8PB34
names: Similarity
messages: Belongs to the UPF0758 family.

1850246:LPB138 RS14505
gene id: 1850246:LPB138_RS14505
uniprot id: A0A1D8PB79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1850246:LPB138 RS11990
gene id: 1850246:LPB138_RS11990
uniprot id: A0A1D8P9T1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1850246:LPB138 RS14215
gene id: 1850246:LPB138_RS14215
uniprot id: A0A1D8PB10
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1850246:LPB138 RS09345
gene id: 1850246:LPB138_RS09345
uniprot id: A0A1D8P8F8
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS00075
gene id: 1850246:LPB138_RS00075
uniprot id: A0A1D8P3M0
names: Similarity
messages: Belongs to the peptidase S8 family.

1850246:LPB138 RS01610
gene id: 1850246:LPB138_RS01610
uniprot id: A0A1D8P4E7
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS06065
gene id: 1850246:LPB138_RS06065
uniprot id: A0A1D8P6U4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1850246:LPB138 RS01995
gene id: 1850246:LPB138_RS01995
uniprot id: A0A1D8P4N7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1850246:LPB138 RS15040
gene id: 1850246:LPB138_RS15040
uniprot id: A0A1D8PBH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS13285
gene id: 1850246:LPB138_RS13285
uniprot id: A0A1D8PC13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1850246:LPB138 RS02880
gene id: 1850246:LPB138_RS02880
uniprot id: A0A1D8P544
names: Similarity
messages: Belongs to the peptidase S9C family.

1850246:LPB138 RS07650
gene id: 1850246:LPB138_RS07650
uniprot id: A0A1D8P7M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS09940
gene id: 1850246:LPB138_RS09940
uniprot id: A0A1D8P8S1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1850246:LPB138 RS13425
gene id: 1850246:LPB138_RS13425
uniprot id: A0A1D8PAK6
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS10600
gene id: 1850246:LPB138_RS10600
uniprot id: A0A1D8P974
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1850246:LPB138 RS00495
gene id: 1850246:LPB138_RS00495
uniprot id: A0A1D8P3W7
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS05075
gene id: 1850246:LPB138_RS05075
uniprot id: A0A1D8P688
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1850246:LPB138 RS12505
gene id: 1850246:LPB138_RS12505
uniprot id: A0A1D8PA29
names: Similarity
messages: Belongs to the asparaginase 1 family.

1850246:LPB138 RS02400
gene id: 1850246:LPB138_RS02400
uniprot id: A0A1D8P4W7
names: Similarity
messages: Belongs to the argonaute family. Long pAgo subfamily.

1850246:LPB138 RS01445
gene id: 1850246:LPB138_RS01445
uniprot id: A0A1D8P4D1
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS05920
gene id: 1850246:LPB138_RS05920
uniprot id: A0A1D8P6P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS03100
gene id: 1850246:LPB138_RS03100
uniprot id: A0A1D8P571
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1850246:LPB138 RS14975
gene id: 1850246:LPB138_RS14975
uniprot id: A0A1D8PBF3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1850246:LPB138 RS04785
gene id: 1850246:LPB138_RS04785
uniprot id: A0A1D8P638
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1850246:LPB138 RS03745
gene id: 1850246:LPB138_RS03745
uniprot id: A0A1D8P5N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1850246:LPB138 RS02875
gene id: 1850246:LPB138_RS02875
uniprot id: A0A1D8P535
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

1850246:LPB138 RS12605
gene id: 1850246:LPB138_RS12605
uniprot id: A0A1D8PA43
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1850246:LPB138 RS09465
gene id: 1850246:LPB138_RS09465
uniprot id: A0A1D8P8H5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1850246:LPB138 RS05055
gene id: 1850246:LPB138_RS05055
uniprot id: A0A1D8P690
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1850246:LPB138 RS12600
gene id: 1850246:LPB138_RS12600
uniprot id: A0A1D8PA47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1850246:LPB138 RS10940
gene id: 1850246:LPB138_RS10940
uniprot id: A0A1D8P9A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1850246:LPB138 RS03245
gene id: 1850246:LPB138_RS03245
uniprot id: A0A1D8P5D1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS02145
gene id: 1850246:LPB138_RS02145
uniprot id: A0A1D8P4N6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1850246:LPB138 RS06045
gene id: 1850246:LPB138_RS06045
uniprot id: A0A1D8P6S0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1850246:LPB138 RS10770
gene id: 1850246:LPB138_RS10770
uniprot id: A0A1D8P981
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1850246:LPB138 RS10400
gene id: 1850246:LPB138_RS10400
uniprot id: A0A1D8P922
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850246:LPB138 RS12385
gene id: 1850246:LPB138_RS12385
uniprot id: A0A1D8PA17
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS13260
gene id: 1850246:LPB138_RS13260
uniprot id: A0A1D8PAK0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1850246:LPB138 RS05700
gene id: 1850246:LPB138_RS05700
uniprot id: A0A1D8P6J0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1850246:LPB138 RS06350
gene id: 1850246:LPB138_RS06350
uniprot id: A0A1D8P6X6
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1850246:LPB138 RS13265
gene id: 1850246:LPB138_RS13265
uniprot id: A0A1D8PAH1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1850246:LPB138 RS02670
gene id: 1850246:LPB138_RS02670
uniprot id: A0A1D8P4Z7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1850246:LPB138 RS06560
gene id: 1850246:LPB138_RS06560
uniprot id: A0A1D8PBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1850246:LPB138 RS13290
gene id: 1850246:LPB138_RS13290
uniprot id: A0A1D8PAK5
names: Similarity
messages: Belongs to the fabD family.

1850246:LPB138 RS10245
gene id: 1850246:LPB138_RS10245
uniprot id: A0A1D8P8X4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS04815
gene id: 1850246:LPB138_RS04815
uniprot id: A0A1D8P647
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1850246:LPB138 RS10445
gene id: 1850246:LPB138_RS10445
uniprot id: A0A1D8P932
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1850246:LPB138 RS06815
gene id: 1850246:LPB138_RS06815
uniprot id: A0A1D8P755
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1850246:LPB138 RS00215
gene id: 1850246:LPB138_RS00215
uniprot id: A0A1D8P3N7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1850246:LPB138 RS11175
gene id: 1850246:LPB138_RS11175
uniprot id: A0A1D8P9G9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1850246:LPB138 RS10870
gene id: 1850246:LPB138_RS10870
uniprot id: A0A1D8P9B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1850246:LPB138 RS05620
gene id: 1850246:LPB138_RS05620
uniprot id: A0A1D8P6H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1850246:LPB138 RS02100
gene id: 1850246:LPB138_RS02100
uniprot id: A0A1D8P4P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1850246:LPB138 RS03405
gene id: 1850246:LPB138_RS03405
uniprot id: A0A1D8P5D8
names: Similarity
messages: Belongs to the toxin_10 family.

1850246:LPB138 RS14910
gene id: 1850246:LPB138_RS14910
uniprot id: A0A1D8PBF5
names: Similarity
messages: Belongs to the UPF0246 family.

1850246:LPB138 RS02525
gene id: 1850246:LPB138_RS02525
uniprot id: A0A1D8P532
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1850246:LPB138 RS15170
gene id: 1850246:LPB138_RS15170
uniprot id: A0A1D8PC51
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1850246:LPB138 RS05615
gene id: 1850246:LPB138_RS05615
uniprot id: A0A1D8P6K5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1850246:LPB138 RS09565
gene id: 1850246:LPB138_RS09565
uniprot id: A0A1D8P8L7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS03820
gene id: 1850246:LPB138_RS03820
uniprot id: A0A1D8P5M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1850246:LPB138 RS13675
gene id: 1850246:LPB138_RS13675
uniprot id: A0A1D8PAQ2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS15005
gene id: 1850246:LPB138_RS15005
uniprot id: A0A1D8PBG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1850246:LPB138 RS08425
gene id: 1850246:LPB138_RS08425
uniprot id: A0A1D8P810
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS03140
gene id: 1850246:LPB138_RS03140
uniprot id: A0A1D8P5B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1850246:LPB138 RS09295
gene id: 1850246:LPB138_RS09295
uniprot id: A0A1D8P8E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1850246:LPB138 RS07385
gene id: 1850246:LPB138_RS07385
uniprot id: A0A1D8P7F0
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS10305
gene id: 1850246:LPB138_RS10305
uniprot id: A0A1D8P8Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1850246:LPB138 RS11400
gene id: 1850246:LPB138_RS11400
uniprot id: A0A1D8P9K2
names: Similarity
messages: Belongs to the universal stress protein A family.

1850246:LPB138 RS13270
gene id: 1850246:LPB138_RS13270
uniprot id: A0A1D8PAH4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1850246:LPB138 RS00995
gene id: 1850246:LPB138_RS00995
uniprot id: A0A1D8P423
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS04915
gene id: 1850246:LPB138_RS04915
uniprot id: A0A1D8P658
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1850246:LPB138 RS03860
gene id: 1850246:LPB138_RS03860
uniprot id: A0A1D8P5Q2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850246:LPB138 RS00500
gene id: 1850246:LPB138_RS00500
uniprot id: A0A1D8P3Z9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1850246:LPB138 RS02550
gene id: 1850246:LPB138_RS02550
uniprot id: A0A1D8P4Z3
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS03880
gene id: 1850246:LPB138_RS03880
uniprot id: A0A1D8P5M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS01685
gene id: 1850246:LPB138_RS01685
uniprot id: A0A1D8P4G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1850246:LPB138 RS06455
gene id: 1850246:LPB138_RS06455
uniprot id: A0A1D8P6Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1850246:LPB138 RS06320
gene id: 1850246:LPB138_RS06320
uniprot id: A0A1D8P6W8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1850246:LPB138 RS03850
gene id: 1850246:LPB138_RS03850
uniprot id: A0A1D8P5L2
names: Similarity
messages: Belongs to the HSP15 family.

1850246:LPB138 RS14835
gene id: 1850246:LPB138_RS14835
uniprot id: A0A1D8PBC6
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS01660
gene id: 1850246:LPB138_RS01660
uniprot id: A0A1D8P4F8
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS01345
gene id: 1850246:LPB138_RS01345
uniprot id: A0A1D8P4B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1850246:LPB138 RS08270
gene id: 1850246:LPB138_RS08270
uniprot id: A0A1D8P7X6
names: Similarity
messages: Belongs to the universal stress protein A family.

1850246:LPB138 RS08025
gene id: 1850246:LPB138_RS08025
uniprot id: A0A1D8P7S9
names: Similarity
messages: Belongs to the peptidase S49 family.

1850246:LPB138 RS10465
gene id: 1850246:LPB138_RS10465
uniprot id: A0A1D8P928
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS13085
gene id: 1850246:LPB138_RS13085
uniprot id: A0A1D8PAF4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1850246:LPB138 RS05915
gene id: 1850246:LPB138_RS05915
uniprot id: A0A1D8P6N7
names: Similarity
messages: Belongs to the UPF0173 family.

1850246:LPB138 RS01695
gene id: 1850246:LPB138_RS01695
uniprot id: A0A1D8P4J8
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1850246:LPB138 RS00535
gene id: 1850246:LPB138_RS00535
uniprot id: A0A1D8P3U9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1850246:LPB138 RS06365
gene id: 1850246:LPB138_RS06365
uniprot id: A0A1D8P6X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS14510
gene id: 1850246:LPB138_RS14510
uniprot id: A0A1D8PB66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1850246:LPB138 RS06830
gene id: 1850246:LPB138_RS06830
uniprot id: A0A1D8P760
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS12485
gene id: 1850246:LPB138_RS12485
uniprot id: A0A1D8PA56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1850246:LPB138 RS11100
gene id: 1850246:LPB138_RS11100
uniprot id: A0A1D8P9H6
names: Similarity
messages: Belongs to the DprA/Smf family.

1850246:LPB138 RS10415
gene id: 1850246:LPB138_RS10415
uniprot id: A0A1D8P921
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1850246:LPB138 RS05640
gene id: 1850246:LPB138_RS05640
uniprot id: A0A1D8P6J7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1850246:LPB138 RS02995
gene id: 1850246:LPB138_RS02995
uniprot id: A0A1D8P559
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1850246:LPB138 RS15960
gene id: 1850246:LPB138_RS15960
uniprot id: A0A1D8P6X1
names: Similarity
messages: Belongs to the SusD family.

1850246:LPB138 RS14980
gene id: 1850246:LPB138_RS14980
uniprot id: A0A1D8PBF6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1850246:LPB138 RS14945
gene id: 1850246:LPB138_RS14945
uniprot id: A0A1D8PBG8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1850246:LPB138 RS04740
gene id: 1850246:LPB138_RS04740
uniprot id: A0A1D8P627
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1850246:LPB138 RS04270
gene id: 1850246:LPB138_RS04270
uniprot id: A0A1D8P5V8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS02615
gene id: 1850246:LPB138_RS02615
uniprot id: A0A1D8P4Y6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1850246:LPB138 RS15140
gene id: 1850246:LPB138_RS15140
uniprot id: A0A1D8PBQ7
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1850246:LPB138 RS08285
gene id: 1850246:LPB138_RS08285
uniprot id: A0A1D8PBU3
names: Similarity
messages: Belongs to the universal stress protein A family.

1850246:LPB138 RS06310
gene id: 1850246:LPB138_RS06310
uniprot id: A0A1D8P6W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1850246:LPB138 RS00010
gene id: 1850246:LPB138_RS00010
uniprot id: A0A1D8P3J8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1850246:LPB138 RS06715
gene id: 1850246:LPB138_RS06715
uniprot id: A0A1D8P747
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1850246:LPB138 RS07595
gene id: 1850246:LPB138_RS07595
uniprot id: A0A1D8P7K6
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS00150
gene id: 1850246:LPB138_RS00150
uniprot id: A0A1D8P3T0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1850246:LPB138 RS03530
gene id: 1850246:LPB138_RS03530
uniprot id: A0A1D8P5G1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1850246:LPB138 RS09580
gene id: 1850246:LPB138_RS09580
uniprot id: A0A1D8P8K3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS04420
gene id: 1850246:LPB138_RS04420
uniprot id: A0A1D8P5X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1850246:LPB138 RS06655
gene id: 1850246:LPB138_RS06655
uniprot id: A0A1D8P732
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1850246:LPB138 RS07935
gene id: 1850246:LPB138_RS07935
uniprot id: A0A1D8P7R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1850246:LPB138 RS07805
gene id: 1850246:LPB138_RS07805
uniprot id: A0A1D8P7N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1850246:LPB138 RS03510
gene id: 1850246:LPB138_RS03510
uniprot id: A0A1D8P5G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1850246:LPB138 RS09005
gene id: 1850246:LPB138_RS09005
uniprot id: A0A1D8P8A4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1850246:LPB138 RS13420
gene id: 1850246:LPB138_RS13420
uniprot id: A0A1D8PAK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1850246:LPB138 RS13205
gene id: 1850246:LPB138_RS13205
uniprot id: A0A1D8PAK4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1850246:LPB138 RS10880
gene id: 1850246:LPB138_RS10880
uniprot id: A0A1D8P999
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1850246:LPB138 RS05330
gene id: 1850246:LPB138_RS05330
uniprot id: A0A1D8P6E0
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1850246:LPB138 RS02800
gene id: 1850246:LPB138_RS02800
uniprot id: A0A1D8P513
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1850246:LPB138 RS10395
gene id: 1850246:LPB138_RS10395
uniprot id: A0A1D8P918
names: Similarity
messages: Belongs to the glutamate synthase family.

1850246:LPB138 RS00205
gene id: 1850246:LPB138_RS00205
uniprot id: A0A1D8P3V2
names: Similarity
messages: Belongs to the CarB family.

1850246:LPB138 RS13655
gene id: 1850246:LPB138_RS13655
uniprot id: A0A1D8PAR0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS02765
gene id: 1850246:LPB138_RS02765
uniprot id: A0A1D8P545
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850246:LPB138 RS07615
gene id: 1850246:LPB138_RS07615
uniprot id: A0A1D8P7J7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1850246:LPB138 RS15150
gene id: 1850246:LPB138_RS15150
uniprot id: A0A1D8PBK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1850246:LPB138 RS06605
gene id: 1850246:LPB138_RS06605
uniprot id: A0A1D8P723
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS05705
gene id: 1850246:LPB138_RS05705
uniprot id: A0A1D8P6J9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1850246:LPB138 RS06990
gene id: 1850246:LPB138_RS06990
uniprot id: A0A1D8P794
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1850246:LPB138 RS06165
gene id: 1850246:LPB138_RS06165
uniprot id: A0A1D8P6W4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1850246:LPB138 RS13910
gene id: 1850246:LPB138_RS13910
uniprot id: A0A1D8PAW1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1850246:LPB138 RS13250
gene id: 1850246:LPB138_RS13250
uniprot id: A0A1D8PAL8
names: Similarity
messages: Belongs to the EPSP synthase family.

1850246:LPB138 RS02500
gene id: 1850246:LPB138_RS02500
uniprot id: A0A1D8P4Y7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1850246:LPB138 RS06325
gene id: 1850246:LPB138_RS06325
uniprot id: A0A1D8P6W9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS02415
gene id: 1850246:LPB138_RS02415
uniprot id: A0A1D8P4T0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1850246:LPB138 RS08955
gene id: 1850246:LPB138_RS08955
uniprot id: A0A1D8P898
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1850246:LPB138 RS09315
gene id: 1850246:LPB138_RS09315
uniprot id: A0A1D8P8F7
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1850246:LPB138 RS03280
gene id: 1850246:LPB138_RS03280
uniprot id: A0A1D8P5D9
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1850246:LPB138 RS13475
gene id: 1850246:LPB138_RS13475
uniprot id: A0A1D8PAL7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1850246:LPB138 RS11780
gene id: 1850246:LPB138_RS11780
uniprot id: A0A1D8P9W5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1850246:LPB138 RS03760
gene id: 1850246:LPB138_RS03760
uniprot id: A0A1D8P5N0
names: Similarity
messages: Belongs to the peptidase M24B family.

1850246:LPB138 RS07490
gene id: 1850246:LPB138_RS07490
uniprot id: A0A1D8P7K4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1850246:LPB138 RS10015
gene id: 1850246:LPB138_RS10015
uniprot id: A0A1D8P8T3
names: Similarity
messages: Belongs to the RecJ family.

1850246:LPB138 RS14810
gene id: 1850246:LPB138_RS14810
uniprot id: A0A1D8PBC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1850246:LPB138 RS03165
gene id: 1850246:LPB138_RS03165
uniprot id: A0A1D8P5E0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1850246:LPB138 RS11185
gene id: 1850246:LPB138_RS11185
uniprot id: A0A1D8P9F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1850246:LPB138 RS13740
gene id: 1850246:LPB138_RS13740
uniprot id: A0A1D8PAU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1850246:LPB138 RS12040
gene id: 1850246:LPB138_RS12040
uniprot id: A0A1D8P9W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1850246:LPB138 RS03935
gene id: 1850246:LPB138_RS03935
uniprot id: A0A1D8P5N9
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS00815
gene id: 1850246:LPB138_RS00815
uniprot id: A0A1D8P3Y9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1850246:LPB138 RS11655
gene id: 1850246:LPB138_RS11655
uniprot id: A0A1D8P9T8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1850246:LPB138 RS12745
gene id: 1850246:LPB138_RS12745
uniprot id: A0A1D8PAA1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1850246:LPB138 RS02020
gene id: 1850246:LPB138_RS02020
uniprot id: A0A1D8PBT4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1850246:LPB138 RS05830
gene id: 1850246:LPB138_RS05830
uniprot id: A0A1D8P6N3
names: Similarity
messages: Belongs to the pirin family.

1850246:LPB138 RS14405
gene id: 1850246:LPB138_RS14405
uniprot id: A0A1D8PB68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1850246:LPB138 RS01560
gene id: 1850246:LPB138_RS01560
uniprot id: A0A1D8P4D4
names: Similarity
messages: Belongs to the ArsC family.

1850246:LPB138 RS08695
gene id: 1850246:LPB138_RS08695
uniprot id: A0A1D8P852
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1850246:LPB138 RS11165
gene id: 1850246:LPB138_RS11165
uniprot id: A0A1D8P9G4
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS14395
gene id: 1850246:LPB138_RS14395
uniprot id: A0A1D8PB55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1850246:LPB138 RS13830
gene id: 1850246:LPB138_RS13830
uniprot id: A0A1D8PAT4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1850246:LPB138 RS10030
gene id: 1850246:LPB138_RS10030
uniprot id: A0A1D8P8W8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1850246:LPB138 RS05785
gene id: 1850246:LPB138_RS05785
uniprot id: A0A1D8P6L0
names: Similarity
messages: Belongs to the ParB family.

1850246:LPB138 RS14500
gene id: 1850246:LPB138_RS14500
uniprot id: A0A1D8PB81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1850246:LPB138 RS05470
gene id: 1850246:LPB138_RS05470
uniprot id: A0A1D8PBQ6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850246:LPB138 RS00240
gene id: 1850246:LPB138_RS00240
uniprot id: A0A1D8P3Q4
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1850246:LPB138 RS02900
gene id: 1850246:LPB138_RS02900
uniprot id: A0A1D8P536
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

1850246:LPB138 RS04275
gene id: 1850246:LPB138_RS04275
uniprot id: A0A1D8P5Y2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1850246:LPB138 RS12455
gene id: 1850246:LPB138_RS12455
uniprot id: A0A1D8PA72
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1850246:LPB138 RS09045
gene id: 1850246:LPB138_RS09045
uniprot id: A0A1D8P8A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1850246:LPB138 RS00045
gene id: 1850246:LPB138_RS00045
uniprot id: A0A1D8P3N3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1850246:LPB138 RS00125
gene id: 1850246:LPB138_RS00125
uniprot id: A0A1D8P3M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1850246:LPB138 RS10065
gene id: 1850246:LPB138_RS10065
uniprot id: A0A1D8P8U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS10410
gene id: 1850246:LPB138_RS10410
uniprot id: A0A1D8P919
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1850246:LPB138 RS14020
gene id: 1850246:LPB138_RS14020
uniprot id: A0A1D8PAX9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS14390
gene id: 1850246:LPB138_RS14390
uniprot id: A0A1D8PB51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1850246:LPB138 RS06970
gene id: 1850246:LPB138_RS06970
uniprot id: A0A1D8P785
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1850246:LPB138 RS09720
gene id: 1850246:LPB138_RS09720
uniprot id: A0A1D8P8M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1850246:LPB138 RS10670
gene id: 1850246:LPB138_RS10670
uniprot id: A0A1D8P963
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1850246:LPB138 RS05295
gene id: 1850246:LPB138_RS05295
uniprot id: A0A1D8P6D1
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

1850246:LPB138 RS12115
gene id: 1850246:LPB138_RS12115
uniprot id: A0A1D8P9W4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1850246:LPB138 RS07115
gene id: 1850246:LPB138_RS07115
uniprot id: A0A1D8P797
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS11820
gene id: 1850246:LPB138_RS11820
uniprot id: A0A1D8P9R6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1850246:LPB138 RS06000
gene id: 1850246:LPB138_RS06000
uniprot id: A0A1D8P6R5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS14440
gene id: 1850246:LPB138_RS14440
uniprot id: A0A1D8PB63
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1850246:LPB138 RS04175
gene id: 1850246:LPB138_RS04175
uniprot id: A0A1D8P5X0
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1850246:LPB138 RS04900
gene id: 1850246:LPB138_RS04900
uniprot id: A0A1D8P659
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1850246:LPB138 RS13310
gene id: 1850246:LPB138_RS13310
uniprot id: A0A1D8PAM0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1850246:LPB138 RS08420
gene id: 1850246:LPB138_RS08420
uniprot id: A0A1D8P800
names: Similarity
messages: Belongs to the SusD family.

1850246:LPB138 RS05255
gene id: 1850246:LPB138_RS05255
uniprot id: A0A1D8P6C7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS05485
gene id: 1850246:LPB138_RS05485
uniprot id: A0A1D8P6G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1850246:LPB138 RS02985
gene id: 1850246:LPB138_RS02985
uniprot id: A0A1D8P556
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

1850246:LPB138 RS02600
gene id: 1850246:LPB138_RS02600
uniprot id: A0A1D8P502
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS02480
gene id: 1850246:LPB138_RS02480
uniprot id: A0A1D8P4U7
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS13255
gene id: 1850246:LPB138_RS13255
uniprot id: A0A1D8PAL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1850246:LPB138 RS12015
gene id: 1850246:LPB138_RS12015
uniprot id: A0A1D8PA31
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1850246:LPB138 RS13540
gene id: 1850246:LPB138_RS13540
uniprot id: A0A1D8PAN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1850246:LPB138 RS07455
gene id: 1850246:LPB138_RS07455
uniprot id: A0A1D8P7J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

1850246:LPB138 RS10920
gene id: 1850246:LPB138_RS10920
uniprot id: A0A1D8PBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1850246:LPB138 RS12930
gene id: 1850246:LPB138_RS12930
uniprot id: A0A1D8PAB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS00320
gene id: 1850246:LPB138_RS00320
uniprot id: A0A1D8P3S4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1850246:LPB138 RS09235
gene id: 1850246:LPB138_RS09235
uniprot id: A0A1D8P8E3
names: Similarity
messages: Belongs to the SCO1/2 family.

1850246:LPB138 RS12695
gene id: 1850246:LPB138_RS12695
uniprot id: A0A1D8PA81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1850246:LPB138 RS11060
gene id: 1850246:LPB138_RS11060
uniprot id: A0A1D8P9F8
names: Similarity
messages: Belongs to the peptidase M4 family.

1850246:LPB138 RS04665
gene id: 1850246:LPB138_RS04665
uniprot id: A0A1D8P640
names: Similarity
messages: Belongs to the AHA1 family.

1850246:LPB138 RS03260
gene id: 1850246:LPB138_RS03260
uniprot id: A0A1D8P5B4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850246:LPB138 RS00230
gene id: 1850246:LPB138_RS00230
uniprot id: A0A1D8P3N4
names: Similarity
messages: Belongs to the sterol desaturase family.

1850246:LPB138 RS04685
gene id: 1850246:LPB138_RS04685
uniprot id: A0A1D8P619
names: Similarity
messages: Belongs to the universal stress protein A family.

1850246:LPB138 RS14630
gene id: 1850246:LPB138_RS14630
uniprot id: A0A1D8PB97
names: Similarity
messages: Belongs to the IlvD/Edd family.

1850246:LPB138 RS00660
gene id: 1850246:LPB138_RS00660
uniprot id: A0A1D8P3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1850246:LPB138 RS04325
gene id: 1850246:LPB138_RS04325
uniprot id: A0A1D8P5W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1850246:LPB138 RS02285
gene id: 1850246:LPB138_RS02285
uniprot id: A0A1D8P4U3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1850246:LPB138 RS14245
gene id: 1850246:LPB138_RS14245
uniprot id: A0A1D8PB25
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1850246:LPB138 RS10230
gene id: 1850246:LPB138_RS10230
uniprot id: A0A1D8P8W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1850246:LPB138 RS04640
gene id: 1850246:LPB138_RS04640
uniprot id: A0A1D8P646
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1850246:LPB138 RS07870
gene id: 1850246:LPB138_RS07870
uniprot id: A0A1D8P7R6
names: Similarity
messages: Belongs to the thioredoxin family.

1850246:LPB138 RS05860
gene id: 1850246:LPB138_RS05860
uniprot id: A0A1D8P6M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1850246:LPB138 RS12870
gene id: 1850246:LPB138_RS12870
uniprot id: A0A1D8PAD1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1850246:LPB138 RS02820
gene id: 1850246:LPB138_RS02820
uniprot id: A0A1D8P523
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

1850246:LPB138 RS06740
gene id: 1850246:LPB138_RS06740
uniprot id: A0A1D8P754
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1850246:LPB138 RS06615
gene id: 1850246:LPB138_RS06615
uniprot id: A0A1D8P718
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1850246:LPB138 RS11875
gene id: 1850246:LPB138_RS11875
uniprot id: A0A1D8P9V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1850246:LPB138 RS13415
gene id: 1850246:LPB138_RS13415
uniprot id: A0A1D8PAN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS02635
gene id: 1850246:LPB138_RS02635
uniprot id: A0A1D8P4W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1850246:LPB138 RS14930
gene id: 1850246:LPB138_RS14930
uniprot id: A0A1D8PBE9
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1850246:LPB138 RS06140
gene id: 1850246:LPB138_RS06140
uniprot id: A0A1D8P6V2
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

1850246:LPB138 RS03400
gene id: 1850246:LPB138_RS03400
uniprot id: A0A1D8P5E1
names: Similarity
messages: Belongs to the peptidase S8 family.

1850246:LPB138 RS12045
gene id: 1850246:LPB138_RS12045
uniprot id: A0A1D8P9X9
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS05735
gene id: 1850246:LPB138_RS05735
uniprot id: A0A1D8P6P4
names: Similarity
messages: Belongs to the LOG family.

1850246:LPB138 RS07245
gene id: 1850246:LPB138_RS07245
uniprot id: A0A1D8P7C5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1850246:LPB138 RS07905
gene id: 1850246:LPB138_RS07905
uniprot id: A0A1D8P7Q1
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1850246:LPB138 RS01575
gene id: 1850246:LPB138_RS01575
uniprot id: A0A1D8P4D2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1850246:LPB138 RS05720
gene id: 1850246:LPB138_RS05720
uniprot id: A0A1D8P6K8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS02790
gene id: 1850246:LPB138_RS02790
uniprot id: A0A1D8P574
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1850246:LPB138 RS09450
gene id: 1850246:LPB138_RS09450
uniprot id: A0A1D8P8K1
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1850246:LPB138 RS14700
gene id: 1850246:LPB138_RS14700
uniprot id: A0A1D8PBB4
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1850246:LPB138 RS11420
gene id: 1850246:LPB138_RS11420
uniprot id: A0A1D8P9J3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS00710
gene id: 1850246:LPB138_RS00710
uniprot id: A0A1D8P3Y7
names: Similarity
messages: Belongs to the DEAD box helicase family.

1850246:LPB138 RS06050
gene id: 1850246:LPB138_RS06050
uniprot id: A0A1D8P6R4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1850246:LPB138 RS10315
gene id: 1850246:LPB138_RS10315
uniprot id: A0A1D8P933
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1850246:LPB138 RS08535
gene id: 1850246:LPB138_RS08535
uniprot id: A0A1D8P826
names: Similarity
messages: Belongs to the RelE toxin family.

1850246:LPB138 RS00615
gene id: 1850246:LPB138_RS00615
uniprot id: A0A1D8P3W6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1850246:LPB138 RS07900
gene id: 1850246:LPB138_RS07900
uniprot id: A0A1D8P7R4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1850246:LPB138 RS10100
gene id: 1850246:LPB138_RS10100
uniprot id: A0A1D8P8V9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS05350
gene id: 1850246:LPB138_RS05350
uniprot id: A0A1D8P6E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS03640
gene id: 1850246:LPB138_RS03640
uniprot id: A0A1D8P5L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS04340
gene id: 1850246:LPB138_RS04340
uniprot id: A0A1D8P5U2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1850246:LPB138 RS09205
gene id: 1850246:LPB138_RS09205
uniprot id: A0A1D8PBZ1
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS09275
gene id: 1850246:LPB138_RS09275
uniprot id: A0A1D8P8H8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1850246:LPB138 RS07425
gene id: 1850246:LPB138_RS07425
uniprot id: A0A1D8P7F7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1850246:LPB138 RS03250
gene id: 1850246:LPB138_RS03250
uniprot id: A0A1D8P591
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850246:LPB138 RS05695
gene id: 1850246:LPB138_RS05695
uniprot id: A0A1D8P6L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1850246:LPB138 RS06865
gene id: 1850246:LPB138_RS06865
uniprot id: A0A1D8P761
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS02530
gene id: 1850246:LPB138_RS02530
uniprot id: A0A1D8P4V1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1850246:LPB138 RS09290
gene id: 1850246:LPB138_RS09290
uniprot id: A0A1D8PC00
names: Similarity
messages: Belongs to the group II decarboxylase family.

1850246:LPB138 RS04445
gene id: 1850246:LPB138_RS04445
uniprot id: A0A1D8PBU2
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS13535
gene id: 1850246:LPB138_RS13535
uniprot id: A0A1D8PAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1850246:LPB138 RS01450
gene id: 1850246:LPB138_RS01450
uniprot id: A0A1D8P4C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1850246:LPB138 RS05050
gene id: 1850246:LPB138_RS05050
uniprot id: A0A1D8P678
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS09780
gene id: 1850246:LPB138_RS09780
uniprot id: A0A1D8P8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1850246:LPB138 RS01470
gene id: 1850246:LPB138_RS01470
uniprot id: A0A1D8P4B7
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS12260
gene id: 1850246:LPB138_RS12260
uniprot id: A0A1D8PA01
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS00700
gene id: 1850246:LPB138_RS00700
uniprot id: A0A1D8P3W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1850246:LPB138 RS06755
gene id: 1850246:LPB138_RS06755
uniprot id: A0A1D8P743
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1850246:LPB138 RS00390
gene id: 1850246:LPB138_RS00390
uniprot id: A0A1D8P3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1850246:LPB138 RS03735
gene id: 1850246:LPB138_RS03735
uniprot id: A0A1D8P5K4
names: Similarity
messages: Belongs to the threonine synthase family.

1850246:LPB138 RS10190
gene id: 1850246:LPB138_RS10190
uniprot id: A0A1D8P8Z9
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS04670
gene id: 1850246:LPB138_RS04670
uniprot id: A0A1D8P600
names: Similarity
messages: Belongs to the SUI1 family.

1850246:LPB138 RS09635
gene id: 1850246:LPB138_RS09635
uniprot id: A0A1D8P8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1850246:LPB138 RS09900
gene id: 1850246:LPB138_RS09900
uniprot id: A0A1D8P8S9
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS09435
gene id: 1850246:LPB138_RS09435
uniprot id: A0A1D8P8J6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS07195
gene id: 1850246:LPB138_RS07195
uniprot id: A0A1D8P7E2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1850246:LPB138 RS02150
gene id: 1850246:LPB138_RS02150
uniprot id: A0A1D8P4W3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1850246:LPB138 RS10470
gene id: 1850246:LPB138_RS10470
uniprot id: A0A1D8P930
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1850246:LPB138 RS12880
gene id: 1850246:LPB138_RS12880
uniprot id: A0A1D8PAA3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1850246:LPB138 RS03560
gene id: 1850246:LPB138_RS03560
uniprot id: A0A1D8P5F0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1850246:LPB138 RS09105
gene id: 1850246:LPB138_RS09105
uniprot id: A0A1D8P8C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1850246:LPB138 RS11740
gene id: 1850246:LPB138_RS11740
uniprot id: A0A1D8P9Q7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1850246:LPB138 RS10930
gene id: 1850246:LPB138_RS10930
uniprot id: A0A1D8P9C0
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1850246:LPB138 RS06115
gene id: 1850246:LPB138_RS06115
uniprot id: A0A1D8P6V3
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1850246:LPB138 RS10875
gene id: 1850246:LPB138_RS10875
uniprot id: A0A1D8PC08
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1850246:LPB138 RS03180
gene id: 1850246:LPB138_RS03180
uniprot id: A0A1D8P5A8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS13880
gene id: 1850246:LPB138_RS13880
uniprot id: A0A1D8PAU4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1850246:LPB138 RS11255
gene id: 1850246:LPB138_RS11255
uniprot id: A0A1D8P9G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1850246:LPB138 RS03095
gene id: 1850246:LPB138_RS03095
uniprot id: A0A1D8P569
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS09065
gene id: 1850246:LPB138_RS09065
uniprot id: A0A1D8P8B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1850246:LPB138 RS10320
gene id: 1850246:LPB138_RS10320
uniprot id: A0A1D8P8Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1850246:LPB138 RS14870
gene id: 1850246:LPB138_RS14870
uniprot id: A0A1D8PBE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1850246:LPB138 RS12390
gene id: 1850246:LPB138_RS12390
uniprot id: A0A1D8P9Z6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1850246:LPB138 RS09550
gene id: 1850246:LPB138_RS09550
uniprot id: A0A1D8P8M6
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS14530
gene id: 1850246:LPB138_RS14530
uniprot id: A0A1D8PB85
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1850246:LPB138 RS13640
gene id: 1850246:LPB138_RS13640
uniprot id: A0A1D8PAP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS09000
gene id: 1850246:LPB138_RS09000
uniprot id: A0A1D8P8A6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1850246:LPB138 RS04645
gene id: 1850246:LPB138_RS04645
uniprot id: A0A1D8P5Z5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1850246:LPB138 RS02580
gene id: 1850246:LPB138_RS02580
uniprot id: A0A1D8P4V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1850246:LPB138 RS03620
gene id: 1850246:LPB138_RS03620
uniprot id: A0A1D8P5H9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1850246:LPB138 RS01725
gene id: 1850246:LPB138_RS01725
uniprot id: A0A1D8P4N8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1850246:LPB138 RS03830
gene id: 1850246:LPB138_RS03830
uniprot id: A0A1D8P5L0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1850246:LPB138 RS12545
gene id: 1850246:LPB138_RS12545
uniprot id: A0A1D8PAB3
names: Similarity
messages: Belongs to the sigma-54 factor family.

1850246:LPB138 RS07760
gene id: 1850246:LPB138_RS07760
uniprot id: A0A1D8P7N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1850246:LPB138 RS00095
gene id: 1850246:LPB138_RS00095
uniprot id: A0A1D8P3L2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1850246:LPB138 RS13390
gene id: 1850246:LPB138_RS13390
uniprot id: A0A1D8PAM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1850246:LPB138 RS04845
gene id: 1850246:LPB138_RS04845
uniprot id: A0A1D8P653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1850246:LPB138 RS08410
gene id: 1850246:LPB138_RS08410
uniprot id: A0A1D8P7Z3
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1850246:LPB138 RS03605
gene id: 1850246:LPB138_RS03605
uniprot id: A0A1D8P5H7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS15030
gene id: 1850246:LPB138_RS15030
uniprot id: A0A1D8PBG2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1850246:LPB138 RS14400
gene id: 1850246:LPB138_RS14400
uniprot id: A0A1D8PB61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1850246:LPB138 RS08100
gene id: 1850246:LPB138_RS08100
uniprot id: A0A1D8P7T3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS02485
gene id: 1850246:LPB138_RS02485
uniprot id: A0A1D8P4W4
names: Similarity
messages: Belongs to the universal stress protein A family.

1850246:LPB138 RS12145
gene id: 1850246:LPB138_RS12145
uniprot id: A0A1D8PA00
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS13620
gene id: 1850246:LPB138_RS13620
uniprot id: A0A1D8PAP2
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS14435
gene id: 1850246:LPB138_RS14435
uniprot id: A0A1D8PB57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1850246:LPB138 RS09585
gene id: 1850246:LPB138_RS09585
uniprot id: A0A1D8P8K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1850246:LPB138 RS14470
gene id: 1850246:LPB138_RS14470
uniprot id: A0A1D8PBC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1850246:LPB138 RS04995
gene id: 1850246:LPB138_RS04995
uniprot id: A0A1D8P677
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1850246:LPB138 RS06750
gene id: 1850246:LPB138_RS06750
uniprot id: A0A1D8P759
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS13435
gene id: 1850246:LPB138_RS13435
uniprot id: A0A1D8PAQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1850246:LPB138 RS14190
gene id: 1850246:LPB138_RS14190
uniprot id: A0A1D8PB35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1850246:LPB138 RS00200
gene id: 1850246:LPB138_RS00200
uniprot id: A0A1D8P3M8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1850246:LPB138 RS09245
gene id: 1850246:LPB138_RS09245
uniprot id: A0A1D8P8E9
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS14715
gene id: 1850246:LPB138_RS14715
uniprot id: A0A1D8PBA3
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1850246:LPB138 RS03425
gene id: 1850246:LPB138_RS03425
uniprot id: A0A1D8P5H1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1850246:LPB138 RS14385
gene id: 1850246:LPB138_RS14385
uniprot id: A0A1D8PB49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1850246:LPB138 RS10490
gene id: 1850246:LPB138_RS10490
uniprot id: A0A1D8P926
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

1850246:LPB138 RS10325
gene id: 1850246:LPB138_RS10325
uniprot id: A0A1D8P902
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1850246:LPB138 RS06965
gene id: 1850246:LPB138_RS06965
uniprot id: A0A1D8P7A5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1850246:LPB138 RS12495
gene id: 1850246:LPB138_RS12495
uniprot id: A0A1D8PA33
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1850246:LPB138 RS04170
gene id: 1850246:LPB138_RS04170
uniprot id: A0A1D8P5V0
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1850246:LPB138 RS03650
gene id: 1850246:LPB138_RS03650
uniprot id: A0A1D8P5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1850246:LPB138 RS03740
gene id: 1850246:LPB138_RS03740
uniprot id: A0A1D8P5L8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1850246:LPB138 RS02970
gene id: 1850246:LPB138_RS02970
uniprot id: A0A1D8P558
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1850246:LPB138 RS10505
gene id: 1850246:LPB138_RS10505
uniprot id: A0A1D8PC07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1850246:LPB138 RS04185
gene id: 1850246:LPB138_RS04185
uniprot id: A0A1D8P5S4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1850246:LPB138 RS05625
gene id: 1850246:LPB138_RS05625
uniprot id: A0A1D8P6I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1850246:LPB138 RS02950
gene id: 1850246:LPB138_RS02950
uniprot id: A0A1D8P548
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

1850246:LPB138 RS11950
gene id: 1850246:LPB138_RS11950
uniprot id: A0A1D8P9S7
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1850246:LPB138 RS13345
gene id: 1850246:LPB138_RS13345
uniprot id: A0A1D8PAI9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS14380
gene id: 1850246:LPB138_RS14380
uniprot id: A0A1D8PB48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1850246:LPB138 RS02890
gene id: 1850246:LPB138_RS02890
uniprot id: A0A1D8P592
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1850246:LPB138 RS13300
gene id: 1850246:LPB138_RS13300
uniprot id: A0A1D8PAI4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1850246:LPB138 RS06995
gene id: 1850246:LPB138_RS06995
uniprot id: A0A1D8P7A6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1850246:LPB138 RS06345
gene id: 1850246:LPB138_RS06345
uniprot id: A0A1D8P6X4
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1850246:LPB138 RS05505
gene id: 1850246:LPB138_RS05505
uniprot id: A0A1D8P6H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1850246:LPB138 RS12230
gene id: 1850246:LPB138_RS12230
uniprot id: A0A1D8P9Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1850246:LPB138 RS02010
gene id: 1850246:LPB138_RS02010
uniprot id: A0A1D8P4Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1850246:LPB138 RS11840
gene id: 1850246:LPB138_RS11840
uniprot id: A0A1D8P9S8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS03945
gene id: 1850246:LPB138_RS03945
uniprot id: A0A1D8P5N3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1850246:LPB138 RS09680
gene id: 1850246:LPB138_RS09680
uniprot id: A0A1D8PBW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS13870
gene id: 1850246:LPB138_RS13870
uniprot id: A0A1D8PAX3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1850246:LPB138 RS13185
gene id: 1850246:LPB138_RS13185
uniprot id: A0A1D8PAI6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1850246:LPB138 RS02555
gene id: 1850246:LPB138_RS02555
uniprot id: A0A1D8P4Y3
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1850246:LPB138 RS13150
gene id: 1850246:LPB138_RS13150
uniprot id: A0A1D8PAK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1850246:LPB138 RS06025
gene id: 1850246:LPB138_RS06025
uniprot id: A0A1D8P6R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1850246:LPB138 RS07030
gene id: 1850246:LPB138_RS07030
uniprot id: A0A1D8P780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1850246:LPB138 RS05175
gene id: 1850246:LPB138_RS05175
uniprot id: A0A1D8P6A9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1850246:LPB138 RS06170
gene id: 1850246:LPB138_RS06170
uniprot id: A0A1D8P6U8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1850246:LPB138 RS00770
gene id: 1850246:LPB138_RS00770
uniprot id: A0A1D8P456
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1850246:LPB138 RS05650
gene id: 1850246:LPB138_RS05650
uniprot id: A0A1D8P6J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1850246:LPB138 RS09310
gene id: 1850246:LPB138_RS09310
uniprot id: A0A1D8P8F6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1850246:LPB138 RS01670
gene id: 1850246:LPB138_RS01670
uniprot id: A0A1D8P4N2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1850246:LPB138 RS08710
gene id: 1850246:LPB138_RS08710
uniprot id: A0A1D8P893
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1850246:LPB138 RS12975
gene id: 1850246:LPB138_RS12975
uniprot id: A0A1D8PAB4
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS13430
gene id: 1850246:LPB138_RS13430
uniprot id: A0A1D8PAL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS04135
gene id: 1850246:LPB138_RS04135
uniprot id: A0A1D8P5Q1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1850246:LPB138 RS12200
gene id: 1850246:LPB138_RS12200
uniprot id: A0A1D8P9X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1850246:LPB138 RS09975
gene id: 1850246:LPB138_RS09975
uniprot id: A0A1D8P8S0
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS13575
gene id: 1850246:LPB138_RS13575
uniprot id: A0A1D8PAR4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1850246:LPB138 RS14330
gene id: 1850246:LPB138_RS14330
uniprot id: A0A1D8PB44
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1850246:LPB138 RS02640
gene id: 1850246:LPB138_RS02640
uniprot id: A0A1D8P4Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1850246:LPB138 RS05535
gene id: 1850246:LPB138_RS05535
uniprot id: A0A1D8P6H6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1850246:LPB138 RS03495
gene id: 1850246:LPB138_RS03495
uniprot id: A0A1D8P5G3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1850246:LPB138 RS12330
gene id: 1850246:LPB138_RS12330
uniprot id: A0A1D8PA13
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1850246:LPB138 RS04525
gene id: 1850246:LPB138_RS04525
uniprot id: A0A1D8P5X2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1850246:LPB138 RS11200
gene id: 1850246:LPB138_RS11200
uniprot id: A0A1D8P9G1
names: Similarity
messages: Belongs to the ParB family.

1850246:LPB138 RS04690
gene id: 1850246:LPB138_RS04690
uniprot id: A0A1D8P661
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1850246:LPB138 RS05205
gene id: 1850246:LPB138_RS05205
uniprot id: A0A1D8P6C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1850246:LPB138 RS14795
gene id: 1850246:LPB138_RS14795
uniprot id: A0A1D8PBB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1850246:LPB138 RS03695
gene id: 1850246:LPB138_RS03695
uniprot id: A0A1D8P5M5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS07950
gene id: 1850246:LPB138_RS07950
uniprot id: A0A1D8P7S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1850246:LPB138 RS10675
gene id: 1850246:LPB138_RS10675
uniprot id: A0A1D8P983
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1850246:LPB138 RS12225
gene id: 1850246:LPB138_RS12225
uniprot id: A0A1D8P9Z7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1850246:LPB138 RS01550
gene id: 1850246:LPB138_RS01550
uniprot id: A0A1D8P4G1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1850246:LPB138 RS01585
gene id: 1850246:LPB138_RS01585
uniprot id: A0A1D8P4G5
names: Subcellular Location Annotation
messages: Secreted

1850246:LPB138 RS05645
gene id: 1850246:LPB138_RS05645
uniprot id: A0A1D8P6J6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1850246:LPB138 RS08065
gene id: 1850246:LPB138_RS08065
uniprot id: A0A1D8P7U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1850246:LPB138 RS10935
gene id: 1850246:LPB138_RS10935
uniprot id: A0A1D8P9B1
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1850246:LPB138 RS00275
gene id: 1850246:LPB138_RS00275
uniprot id: A0A1D8P3S0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1850246:LPB138 RS04300
gene id: 1850246:LPB138_RS04300
uniprot id: A0A1D8P5W8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1850246:LPB138 RS09790
gene id: 1850246:LPB138_RS09790
uniprot id: A0A1D8P8N6
names: Subcellular Location Annotation
messages: Membrane

1850246:LPB138 RS14565
gene id: 1850246:LPB138_RS14565
uniprot id: A0A1D8PB73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1850246:LPB138 RS14730
gene id: 1850246:LPB138_RS14730
uniprot id: A0A1D8PBA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1850246:LPB138 RS05795
gene id: 1850246:LPB138_RS05795
uniprot id: A0A1D8P6Q0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1850246:LPB138 RS09285
gene id: 1850246:LPB138_RS09285
uniprot id: A0A1D8P8F3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1850246:LPB138 RS13875
gene id: 1850246:LPB138_RS13875
uniprot id: A0A1D8PAW6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.