1847728:BTM29 RS04120
gene id: 1847728:BTM29_RS04120
uniprot id: A0A1P8Q1Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS00160
gene id: 1847728:BTM29_RS00160
uniprot id: A0A1P8PZR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1847728:BTM29 RS00025
gene id: 1847728:BTM29_RS00025
uniprot id: A0A1P8Q610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS00360
gene id: 1847728:BTM29_RS00360
uniprot id: A0A1P8PZP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1847728:BTM29 RS08660
gene id: 1847728:BTM29_RS08660
uniprot id: A0A1P8Q443
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS04205
gene id: 1847728:BTM29_RS04205
uniprot id: A0A1P8Q1U4
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00180
gene id: 1847728:BTM29_RS00180
uniprot id: A0A1P8PZL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1847728:BTM29 RS11280
gene id: 1847728:BTM29_RS11280
uniprot id: A0A1P8Q5H1
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS03455
gene id: 1847728:BTM29_RS03455
uniprot id: A0A1P8Q1K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS11240
gene id: 1847728:BTM29_RS11240
uniprot id: A0A1P8Q5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1847728:BTM29 RS08995
gene id: 1847728:BTM29_RS08995
uniprot id: A0A1P8Q4H5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1847728:BTM29 RS07310
gene id: 1847728:BTM29_RS07310
uniprot id: A0A1P8Q3F6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1847728:BTM29 RS03045
gene id: 1847728:BTM29_RS03045
uniprot id: A0A1P8Q191
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS03645
gene id: 1847728:BTM29_RS03645
uniprot id: A0A1P8Q1E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1847728:BTM29 RS00795
gene id: 1847728:BTM29_RS00795
uniprot id: A0A1P8Q028
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1847728:BTM29 RS07330
gene id: 1847728:BTM29_RS07330
uniprot id: A0A1P8Q3D7
names: Similarity
messages: Belongs to the GSP E family.

1847728:BTM29 RS05595
gene id: 1847728:BTM29_RS05595
uniprot id: A0A1P8Q2L8
names: Similarity
messages: Belongs to the ParB family.

1847728:BTM29 RS03660
gene id: 1847728:BTM29_RS03660
uniprot id: A0A1P8Q1E7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1847728:BTM29 RS10490
gene id: 1847728:BTM29_RS10490
uniprot id: A0A1P8Q522
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1847728:BTM29 RS09660
gene id: 1847728:BTM29_RS09660
uniprot id: A0A1P8Q4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS08030
gene id: 1847728:BTM29_RS08030
uniprot id: A0A1P8Q3X4
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1847728:BTM29 RS05065
gene id: 1847728:BTM29_RS05065
uniprot id: A0A1P8Q258
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1847728:BTM29 RS01600
gene id: 1847728:BTM29_RS01600
uniprot id: A0A1P8Q0C8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1847728:BTM29 RS09595
gene id: 1847728:BTM29_RS09595
uniprot id: A0A1P8Q4M3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1847728:BTM29 RS07345
gene id: 1847728:BTM29_RS07345
uniprot id: A0A1P8Q3I2
names: Function
messages: Required for transformation and DNA binding.

1847728:BTM29 RS11120
gene id: 1847728:BTM29_RS11120
uniprot id: A0A1P8Q5D4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1847728:BTM29 RS11285
gene id: 1847728:BTM29_RS11285
uniprot id: A0A1P8Q5F8
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS02475
gene id: 1847728:BTM29_RS02475
uniprot id: A0A1P8Q115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS04315
gene id: 1847728:BTM29_RS04315
uniprot id: A0A1P8Q1X6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS03185
gene id: 1847728:BTM29_RS03185
uniprot id: A0A1P8Q184
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS03290
gene id: 1847728:BTM29_RS03290
uniprot id: A0A1P8Q1A4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1847728:BTM29 RS10400
gene id: 1847728:BTM29_RS10400
uniprot id: A0A1P8Q501
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1847728:BTM29 RS08450
gene id: 1847728:BTM29_RS08450
uniprot id: A0A1P8Q3Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1847728:BTM29 RS04545
gene id: 1847728:BTM29_RS04545
uniprot id: A0A1P8Q1X4
names: Similarity
messages: Belongs to the XFP family.

1847728:BTM29 RS09730
gene id: 1847728:BTM29_RS09730
uniprot id: A0A1P8Q4M9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS05935
gene id: 1847728:BTM29_RS05935
uniprot id: A0A1P8Q2T0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1847728:BTM29 RS07180
gene id: 1847728:BTM29_RS07180
uniprot id: A0A1P8Q3D6
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1847728:BTM29 RS03545
gene id: 1847728:BTM29_RS03545
uniprot id: A0A1P8Q1C8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1847728:BTM29 RS09375
gene id: 1847728:BTM29_RS09375
uniprot id: A0A1P8Q4I5
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00405
gene id: 1847728:BTM29_RS00405
uniprot id: A0A1P8PZP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1847728:BTM29 RS09435
gene id: 1847728:BTM29_RS09435
uniprot id: A0A1P8Q4G6
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1847728:BTM29 RS11220
gene id: 1847728:BTM29_RS11220
uniprot id: A0A1P8Q5H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1847728:BTM29 RS11215
gene id: 1847728:BTM29_RS11215
uniprot id: A0A1P8Q5E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1847728:BTM29 RS02080
gene id: 1847728:BTM29_RS02080
uniprot id: A0A1P8Q0Q2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1847728:BTM29 RS00640
gene id: 1847728:BTM29_RS00640
uniprot id: A0A1P8PZZ6
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00860
gene id: 1847728:BTM29_RS00860
uniprot id: A0A1P8PZZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1847728:BTM29 RS02035
gene id: 1847728:BTM29_RS02035
uniprot id: A0A1P8Q0Q7
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS04685
gene id: 1847728:BTM29_RS04685
uniprot id: A0A1P8Q1Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1847728:BTM29 RS00775
gene id: 1847728:BTM29_RS00775
uniprot id: A0A1P8PZX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1847728:BTM29 RS12225
gene id: 1847728:BTM29_RS12225
uniprot id: A0A1P8Q609
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS05175
gene id: 1847728:BTM29_RS05175
uniprot id: A0A1P8Q2C3
names: Subcellular Location Annotation
messages: Cytoplasm

1847728:BTM29 RS03655
gene id: 1847728:BTM29_RS03655
uniprot id: A0A1P8Q1E8
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1847728:BTM29 RS04940
gene id: 1847728:BTM29_RS04940
uniprot id: A0A1P8Q245
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1847728:BTM29 RS00615
gene id: 1847728:BTM29_RS00615
uniprot id: A0A1P8Q005
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS04950
gene id: 1847728:BTM29_RS04950
uniprot id: A0A1P8Q238
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1847728:BTM29 RS11100
gene id: 1847728:BTM29_RS11100
uniprot id: A0A1P8Q5E5
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1847728:BTM29 RS02100
gene id: 1847728:BTM29_RS02100
uniprot id: A0A1P8Q618
names: Subcellular Location Annotation
messages: Cell membrane

1847728:BTM29 RS10205
gene id: 1847728:BTM29_RS10205
uniprot id: A0A1P8Q4W6
names: Similarity
messages: Belongs to the DprA/Smf family.

1847728:BTM29 RS06655
gene id: 1847728:BTM29_RS06655
uniprot id: A0A1P8Q316
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1847728:BTM29 RS01100
gene id: 1847728:BTM29_RS01100
uniprot id: A0A1P8Q029
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1847728:BTM29 RS08460
gene id: 1847728:BTM29_RS08460
uniprot id: A0A1P8Q445
names: Similarity
messages: Belongs to the TlyA family.

1847728:BTM29 RS01840
gene id: 1847728:BTM29_RS01840
uniprot id: A0A1P8Q0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS10825
gene id: 1847728:BTM29_RS10825
uniprot id: A0A1P8Q585
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS11990
gene id: 1847728:BTM29_RS11990
uniprot id: A0A1P8Q5X1
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1847728:BTM29 RS08600
gene id: 1847728:BTM29_RS08600
uniprot id: A0A1P8Q427
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1847728:BTM29 RS08515
gene id: 1847728:BTM29_RS08515
uniprot id: A0A1P8Q404
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1847728:BTM29 RS00695
gene id: 1847728:BTM29_RS00695
uniprot id: A0A1P8Q007
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1847728:BTM29 RS00250
gene id: 1847728:BTM29_RS00250
uniprot id: A0A1P8PZM4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1847728:BTM29 RS04460
gene id: 1847728:BTM29_RS04460
uniprot id: A0A1P8Q1V1
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00385
gene id: 1847728:BTM29_RS00385
uniprot id: A0A1P8PZP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1847728:BTM29 RS04130
gene id: 1847728:BTM29_RS04130
uniprot id: A0A1P8Q1P5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1847728:BTM29 RS00035
gene id: 1847728:BTM29_RS00035
uniprot id: A0A1P8PZI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

1847728:BTM29 RS06545
gene id: 1847728:BTM29_RS06545
uniprot id: A0A1P8Q2Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1847728:BTM29 RS10340
gene id: 1847728:BTM29_RS10340
uniprot id: A0A1P8Q4Z7
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS09415
gene id: 1847728:BTM29_RS09415
uniprot id: A0A1P8Q4G1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1847728:BTM29 RS04045
gene id: 1847728:BTM29_RS04045
uniprot id: A0A1P8Q1P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS12245
gene id: 1847728:BTM29_RS12245
uniprot id: A0A1P8Q5Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS03475
gene id: 1847728:BTM29_RS03475
uniprot id: A0A1P8Q1B6
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS04955
gene id: 1847728:BTM29_RS04955
uniprot id: A0A1P8Q239
names: Similarity
messages: Belongs to the TPP enzyme family.

1847728:BTM29 RS06020
gene id: 1847728:BTM29_RS06020
uniprot id: A0A1P8Q2P2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1847728:BTM29 RS02965
gene id: 1847728:BTM29_RS02965
uniprot id: A0A1P8Q130
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1847728:BTM29 RS00440
gene id: 1847728:BTM29_RS00440
uniprot id: A0A1P8PZX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1847728:BTM29 RS10295
gene id: 1847728:BTM29_RS10295
uniprot id: A0A1P8Q4Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1847728:BTM29 RS07520
gene id: 1847728:BTM29_RS07520
uniprot id: A0A1P8Q3H3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1847728:BTM29 RS00415
gene id: 1847728:BTM29_RS00415
uniprot id: A0A1P8PZQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1847728:BTM29 RS06485
gene id: 1847728:BTM29_RS06485
uniprot id: A0A1P8Q2Z3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1847728:BTM29 RS01075
gene id: 1847728:BTM29_RS01075
uniprot id: A0A1P8Q070
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1847728:BTM29 RS08670
gene id: 1847728:BTM29_RS08670
uniprot id: A0A1P8Q490
names: Similarity
messages: Belongs to the GARS family.

1847728:BTM29 RS11590
gene id: 1847728:BTM29_RS11590
uniprot id: A0A1P8Q5N3
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS02210
gene id: 1847728:BTM29_RS02210
uniprot id: A0A1P8Q0P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS07185
gene id: 1847728:BTM29_RS07185
uniprot id: A0A1P8Q3E8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1847728:BTM29 RS04400
gene id: 1847728:BTM29_RS04400
uniprot id: A0A1P8Q1U0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1847728:BTM29 RS03235
gene id: 1847728:BTM29_RS03235
uniprot id: A0A1P8Q1G3
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1847728:BTM29 RS00235
gene id: 1847728:BTM29_RS00235
uniprot id: A0A1P8PZU5
names: Similarity
messages: Belongs to the UPF0177 family.

1847728:BTM29 RS02905
gene id: 1847728:BTM29_RS02905
uniprot id: A0A1P8Q174
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS08710
gene id: 1847728:BTM29_RS08710
uniprot id: A0A1P8Q451
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1847728:BTM29 RS06345
gene id: 1847728:BTM29_RS06345
uniprot id: A0A1P8Q2W2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1847728:BTM29 RS00675
gene id: 1847728:BTM29_RS00675
uniprot id: A0A1P8PZV7
names: Similarity
messages: Belongs to the UPF0045 family.

1847728:BTM29 RS11635
gene id: 1847728:BTM29_RS11635
uniprot id: A0A1P8Q5R2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1847728:BTM29 RS02335
gene id: 1847728:BTM29_RS02335
uniprot id: A0A1P8Q0R0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1847728:BTM29 RS01925
gene id: 1847728:BTM29_RS01925
uniprot id: A0A1P8Q0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1847728:BTM29 RS08215
gene id: 1847728:BTM29_RS08215
uniprot id: A0A1P8Q3U9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS05840
gene id: 1847728:BTM29_RS05840
uniprot id: A0A1P8Q2Q3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1847728:BTM29 RS08315
gene id: 1847728:BTM29_RS08315
uniprot id: A0A1P8Q3V5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1847728:BTM29 RS00730
gene id: 1847728:BTM29_RS00730
uniprot id: A0A1P8PZW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1847728:BTM29 RS08755
gene id: 1847728:BTM29_RS08755
uniprot id: A0A1P8Q456
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1847728:BTM29 RS10555
gene id: 1847728:BTM29_RS10555
uniprot id: A0A1P8Q534
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1847728:BTM29 RS07620
gene id: 1847728:BTM29_RS07620
uniprot id: A0A1P8Q3M9
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1847728:BTM29 RS00895
gene id: 1847728:BTM29_RS00895
uniprot id: A0A1P8Q046
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1847728:BTM29 RS08280
gene id: 1847728:BTM29_RS08280
uniprot id: A0A1P8Q3X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1847728:BTM29 RS04735
gene id: 1847728:BTM29_RS04735
uniprot id: A0A1P8Q1Z8
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

1847728:BTM29 RS04980
gene id: 1847728:BTM29_RS04980
uniprot id: A0A1P8Q265
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1847728:BTM29 RS04180
gene id: 1847728:BTM29_RS04180
uniprot id: A0A1P8Q1Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

1847728:BTM29 RS02530
gene id: 1847728:BTM29_RS02530
uniprot id: A0A1P8Q0V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1847728:BTM29 RS01770
gene id: 1847728:BTM29_RS01770
uniprot id: A0A1P8Q0J5
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS07730
gene id: 1847728:BTM29_RS07730
uniprot id: A0A1P8Q3L6
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1847728:BTM29 RS02945
gene id: 1847728:BTM29_RS02945
uniprot id: A0A1P8Q659
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1847728:BTM29 RS02870
gene id: 1847728:BTM29_RS02870
uniprot id: A0A1P8Q112
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1847728:BTM29 RS05115
gene id: 1847728:BTM29_RS05115
uniprot id: A0A1P8Q660
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS05610
gene id: 1847728:BTM29_RS05610
uniprot id: A0A1P8Q2H7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

1847728:BTM29 RS01825
gene id: 1847728:BTM29_RS01825
uniprot id: A0A1P8Q0K5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1847728:BTM29 RS09710
gene id: 1847728:BTM29_RS09710
uniprot id: A0A1P8Q4N6
names: Caution
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS07635
gene id: 1847728:BTM29_RS07635
uniprot id: A0A1P8Q3P7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1847728:BTM29 RS02400
gene id: 1847728:BTM29_RS02400
uniprot id: A0A1P8Q0W2
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS10805
gene id: 1847728:BTM29_RS10805
uniprot id: A0A1P8Q5A7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1847728:BTM29 RS08770
gene id: 1847728:BTM29_RS08770
uniprot id: A0A1P8Q4C8
names: Similarity
messages: Belongs to the ribF family.

1847728:BTM29 RS04935
gene id: 1847728:BTM29_RS04935
uniprot id: A0A1P8Q648
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1847728:BTM29 RS11105
gene id: 1847728:BTM29_RS11105
uniprot id: A0A1P8Q5D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1847728:BTM29 RS08890
gene id: 1847728:BTM29_RS08890
uniprot id: A0A1P8Q4F6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1847728:BTM29 RS04125
gene id: 1847728:BTM29_RS04125
uniprot id: A0A1P8Q1X7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1847728:BTM29 RS07060
gene id: 1847728:BTM29_RS07060
uniprot id: A0A1P8Q388
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06610
gene id: 1847728:BTM29_RS06610
uniprot id: A0A1P8Q2Z0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1847728:BTM29 RS11125
gene id: 1847728:BTM29_RS11125
uniprot id: A0A1P8Q5D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1847728:BTM29 RS11245
gene id: 1847728:BTM29_RS11245
uniprot id: A0A1P8Q5G0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1847728:BTM29 RS07505
gene id: 1847728:BTM29_RS07505
uniprot id: A0A1P8Q3I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1847728:BTM29 RS07435
gene id: 1847728:BTM29_RS07435
uniprot id: A0A1P8Q3K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06835
gene id: 1847728:BTM29_RS06835
uniprot id: A0A1P8Q346
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1847728:BTM29 RS03995
gene id: 1847728:BTM29_RS03995
uniprot id: A0A1P8Q1V5
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1847728:BTM29 RS09785
gene id: 1847728:BTM29_RS09785
uniprot id: A0A1P8Q4N9
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1847728:BTM29 RS08490
gene id: 1847728:BTM29_RS08490
uniprot id: A0A1P8Q408
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1847728:BTM29 RS10830
gene id: 1847728:BTM29_RS10830
uniprot id: A0A1P8Q574
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1847728:BTM29 RS08185
gene id: 1847728:BTM29_RS08185
uniprot id: A0A1P8Q3U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1847728:BTM29 RS06120
gene id: 1847728:BTM29_RS06120
uniprot id: A0A1P8Q2Y0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1847728:BTM29 RS06810
gene id: 1847728:BTM29_RS06810
uniprot id: A0A1P8Q371
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1847728:BTM29 RS11085
gene id: 1847728:BTM29_RS11085
uniprot id: A0A1P8Q5C1
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1847728:BTM29 RS06675
gene id: 1847728:BTM29_RS06675
uniprot id: A0A1P8Q307
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

1847728:BTM29 RS08615
gene id: 1847728:BTM29_RS08615
uniprot id: A0A1P8Q425
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

1847728:BTM29 RS08720
gene id: 1847728:BTM29_RS08720
uniprot id: A0A1P8Q4C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1847728:BTM29 RS01300
gene id: 1847728:BTM29_RS01300
uniprot id: A0A1P8Q0E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS11720
gene id: 1847728:BTM29_RS11720
uniprot id: A0A1P8Q5Q3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1847728:BTM29 RS04425
gene id: 1847728:BTM29_RS04425
uniprot id: A0A1P8Q1Z7
names: Similarity
messages: Belongs to the thioredoxin family.

1847728:BTM29 RS04680
gene id: 1847728:BTM29_RS04680
uniprot id: A0A1P8Q1Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1847728:BTM29 RS12120
gene id: 1847728:BTM29_RS12120
uniprot id: A0A1P8Q5X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1847728:BTM29 RS00985
gene id: 1847728:BTM29_RS00985
uniprot id: A0A1P8Q014
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1847728:BTM29 RS07230
gene id: 1847728:BTM29_RS07230
uniprot id: A0A1P8Q3E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1847728:BTM29 RS01990
gene id: 1847728:BTM29_RS01990
uniprot id: A0A1P8Q0K1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1847728:BTM29 RS00820
gene id: 1847728:BTM29_RS00820
uniprot id: A0A1P8PZY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1847728:BTM29 RS08625
gene id: 1847728:BTM29_RS08625
uniprot id: A0A1P8Q423
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1847728:BTM29 RS09405
gene id: 1847728:BTM29_RS09405
uniprot id: A0A1P8Q4G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS10300
gene id: 1847728:BTM29_RS10300
uniprot id: A0A1P8Q502
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1847728:BTM29 RS07280
gene id: 1847728:BTM29_RS07280
uniprot id: A0A1P8Q3F3
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1847728:BTM29 RS02410
gene id: 1847728:BTM29_RS02410
uniprot id: A0A1P8Q0T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1847728:BTM29 RS11095
gene id: 1847728:BTM29_RS11095
uniprot id: A0A1P8Q5C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1847728:BTM29 RS08560
gene id: 1847728:BTM29_RS08560
uniprot id: A0A1P8Q424
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1847728:BTM29 RS05945
gene id: 1847728:BTM29_RS05945
uniprot id: A0A1P8Q2P4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1847728:BTM29 RS02940
gene id: 1847728:BTM29_RS02940
uniprot id: A0A1P8Q137
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1847728:BTM29 RS12075
gene id: 1847728:BTM29_RS12075
uniprot id: A0A1P8Q5U9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1847728:BTM29 RS04170
gene id: 1847728:BTM29_RS04170
uniprot id: A0A1P8Q1R2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS01045
gene id: 1847728:BTM29_RS01045
uniprot id: A0A1P8Q022
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1847728:BTM29 RS10765
gene id: 1847728:BTM29_RS10765
uniprot id: A0A1P8Q6C6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1847728:BTM29 RS10455
gene id: 1847728:BTM29_RS10455
uniprot id: A0A1P8Q513
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS05920
gene id: 1847728:BTM29_RS05920
uniprot id: A0A1P8Q2L0
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1847728:BTM29 RS00745
gene id: 1847728:BTM29_RS00745
uniprot id: A0A1P8Q020
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1847728:BTM29 RS11250
gene id: 1847728:BTM29_RS11250
uniprot id: A0A1P8Q5H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1847728:BTM29 RS07120
gene id: 1847728:BTM29_RS07120
uniprot id: A0A1P8Q3C8
names: Similarity
messages: Belongs to the TrpC family.

1847728:BTM29 RS09430
gene id: 1847728:BTM29_RS09430
uniprot id: A0A1P8Q4I9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1847728:BTM29 RS05265
gene id: 1847728:BTM29_RS05265
uniprot id: A0A1P8Q2A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Ycf16 family.
messages: Membrane

1847728:BTM29 RS07380
gene id: 1847728:BTM29_RS07380
uniprot id: A0A1P8Q3E6
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1847728:BTM29 RS08325
gene id: 1847728:BTM29_RS08325
uniprot id: A0A1P8Q3X7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1847728:BTM29 RS04910
gene id: 1847728:BTM29_RS04910
uniprot id: A0A1P8Q273
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1847728:BTM29 RS00770
gene id: 1847728:BTM29_RS00770
uniprot id: A0A1P8PZW9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1847728:BTM29 RS03885
gene id: 1847728:BTM29_RS03885
uniprot id: A0A1P8Q1P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

1847728:BTM29 RS11860
gene id: 1847728:BTM29_RS11860
uniprot id: A0A1P8Q5T6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS10425
gene id: 1847728:BTM29_RS10425
uniprot id: A0A1P8Q514
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1847728:BTM29 RS11020
gene id: 1847728:BTM29_RS11020
uniprot id: A0A1P8Q5B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1847728:BTM29 RS08345
gene id: 1847728:BTM29_RS08345
uniprot id: A0A1P8Q433
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1847728:BTM29 RS05335
gene id: 1847728:BTM29_RS05335
uniprot id: A0A1P8Q2G8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1847728:BTM29 RS05320
gene id: 1847728:BTM29_RS05320
uniprot id: A0A1P8Q2A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1847728:BTM29 RS09100
gene id: 1847728:BTM29_RS09100
uniprot id: A0A1P8Q4E0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS04730
gene id: 1847728:BTM29_RS04730
uniprot id: A0A1P8Q244
names: Similarity
messages: Belongs to the zeta toxin family.

1847728:BTM29 RS06915
gene id: 1847728:BTM29_RS06915
uniprot id: A0A1P8Q391
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1847728:BTM29 RS00135
gene id: 1847728:BTM29_RS00135
uniprot id: A0A1P8PZS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1847728:BTM29 RS00840
gene id: 1847728:BTM29_RS00840
uniprot id: A0A1P8Q040
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1847728:BTM29 RS08780
gene id: 1847728:BTM29_RS08780
uniprot id: A0A1P8Q458
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1847728:BTM29 RS06145
gene id: 1847728:BTM29_RS06145
uniprot id: A0A1P8Q668
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1847728:BTM29 RS02395
gene id: 1847728:BTM29_RS02395
uniprot id: A0A1P8Q0X3
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS10910
gene id: 1847728:BTM29_RS10910
uniprot id: A0A1P8Q6C4
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1847728:BTM29 RS10915
gene id: 1847728:BTM29_RS10915
uniprot id: A0A1P8Q5A1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1847728:BTM29 RS08665
gene id: 1847728:BTM29_RS08665
uniprot id: A0A1P8Q438
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1847728:BTM29 RS10460
gene id: 1847728:BTM29_RS10460
uniprot id: A0A1P8Q556
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00825
gene id: 1847728:BTM29_RS00825
uniprot id: A0A1P8PZY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1847728:BTM29 RS04565
gene id: 1847728:BTM29_RS04565
uniprot id: A0A1P8Q1X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1847728:BTM29 RS06970
gene id: 1847728:BTM29_RS06970
uniprot id: A0A1P8Q3B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1847728:BTM29 RS11045
gene id: 1847728:BTM29_RS11045
uniprot id: A0A1P8Q5C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1847728:BTM29 RS00130
gene id: 1847728:BTM29_RS00130
uniprot id: A0A1P8PZK2
names: Similarity
messages: Belongs to the UPF0473 family.

1847728:BTM29 RS01855
gene id: 1847728:BTM29_RS01855
uniprot id: A0A1P8Q0H1
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS06365
gene id: 1847728:BTM29_RS06365
uniprot id: A0A1P8Q2U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1847728:BTM29 RS00940
gene id: 1847728:BTM29_RS00940
uniprot id: A0A1P8Q061
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1847728:BTM29 RS05900
gene id: 1847728:BTM29_RS05900
uniprot id: A0A1P8Q2N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1847728:BTM29 RS04145
gene id: 1847728:BTM29_RS04145
uniprot id: A0A1P8Q1N9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1847728:BTM29 RS10785
gene id: 1847728:BTM29_RS10785
uniprot id: A0A1P8Q570
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1847728:BTM29 RS12330
gene id: 1847728:BTM29_RS12330
uniprot id: A0A1P8Q637
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS11265
gene id: 1847728:BTM29_RS11265
uniprot id: A0A1P8Q5F6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS05075
gene id: 1847728:BTM29_RS05075
uniprot id: A0A1P8Q2A7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1847728:BTM29 RS08535
gene id: 1847728:BTM29_RS08535
uniprot id: A0A1P8Q426
names: Similarity
messages: Belongs to the asp23 family.

1847728:BTM29 RS10305
gene id: 1847728:BTM29_RS10305
uniprot id: A0A1P8Q6B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1847728:BTM29 RS08685
gene id: 1847728:BTM29_RS08685
uniprot id: A0A1P8Q431
names: Similarity
messages: Belongs to the UPF0213 family.

1847728:BTM29 RS09190
gene id: 1847728:BTM29_RS09190
uniprot id: A0A1P8Q4D3
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1847728:BTM29 RS01645
gene id: 1847728:BTM29_RS01645
uniprot id: A0A1P8Q652
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1847728:BTM29 RS10500
gene id: 1847728:BTM29_RS10500
uniprot id: A0A1P8Q520
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS08350
gene id: 1847728:BTM29_RS08350
uniprot id: A0A1P8Q3X3
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS09765
gene id: 1847728:BTM29_RS09765
uniprot id: A0A1P8Q4P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1847728:BTM29 RS10410
gene id: 1847728:BTM29_RS10410
uniprot id: A0A1P8Q505
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1847728:BTM29 RS09485
gene id: 1847728:BTM29_RS09485
uniprot id: A0A1P8Q4K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1847728:BTM29 RS00900
gene id: 1847728:BTM29_RS00900
uniprot id: A0A1P8Q002
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1847728:BTM29 RS08410
gene id: 1847728:BTM29_RS08410
uniprot id: A0A1P8Q3Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1847728:BTM29 RS04745
gene id: 1847728:BTM29_RS04745
uniprot id: A0A1P8Q200
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1847728:BTM29 RS00255
gene id: 1847728:BTM29_RS00255
uniprot id: A0A1P8PZP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1847728:BTM29 RS01740
gene id: 1847728:BTM29_RS01740
uniprot id: A0A1P8Q0F1
names: Similarity
messages: Belongs to the catalase family.

1847728:BTM29 RS05180
gene id: 1847728:BTM29_RS05180
uniprot id: A0A1P8Q2C9
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS03510
gene id: 1847728:BTM29_RS03510
uniprot id: A0A1P8Q1E1
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS11175
gene id: 1847728:BTM29_RS11175
uniprot id: A0A1P8Q5F1
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS07570
gene id: 1847728:BTM29_RS07570
uniprot id: A0A1P8Q3M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1847728:BTM29 RS04040
gene id: 1847728:BTM29_RS04040
uniprot id: A0A1P8Q1S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS08195
gene id: 1847728:BTM29_RS08195
uniprot id: A0A1P8Q3V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1847728:BTM29 RS09540
gene id: 1847728:BTM29_RS09540
uniprot id: A0A1P8Q4L3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06580
gene id: 1847728:BTM29_RS06580
uniprot id: A0A1P8Q339
names: Similarity
messages: Belongs to the sigma-54 factor family.

1847728:BTM29 RS06455
gene id: 1847728:BTM29_RS06455
uniprot id: A0A1P8Q2W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS09005
gene id: 1847728:BTM29_RS09005
uniprot id: A0A1P8Q497
names: Similarity
messages: Belongs to the RecJ family.

1847728:BTM29 RS05160
gene id: 1847728:BTM29_RS05160
uniprot id: A0A1P8Q283
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS03835
gene id: 1847728:BTM29_RS03835
uniprot id: A0A1P8Q1N6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1847728:BTM29 RS11765
gene id: 1847728:BTM29_RS11765
uniprot id: A0A1P8Q5S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

1847728:BTM29 RS08655
gene id: 1847728:BTM29_RS08655
uniprot id: A0A1P8Q441
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1847728:BTM29 RS06780
gene id: 1847728:BTM29_RS06780
uniprot id: A0A1P8Q326
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1847728:BTM29 RS00705
gene id: 1847728:BTM29_RS00705
uniprot id: A0A1P8Q018
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1847728:BTM29 RS11985
gene id: 1847728:BTM29_RS11985
uniprot id: A0A1P8Q5V5
names: Similarity
messages: Belongs to the FGGY kinase family.

1847728:BTM29 RS07395
gene id: 1847728:BTM29_RS07395
uniprot id: A0A1P8Q3J4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1847728:BTM29 RS09680
gene id: 1847728:BTM29_RS09680
uniprot id: A0A1P8Q4L8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS04430
gene id: 1847728:BTM29_RS04430
uniprot id: A0A1P8Q1W2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1847728:BTM29 RS11060
gene id: 1847728:BTM29_RS11060
uniprot id: A0A1P8Q5F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1847728:BTM29 RS02085
gene id: 1847728:BTM29_RS02085
uniprot id: A0A1P8Q0R7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1847728:BTM29 RS02290
gene id: 1847728:BTM29_RS02290
uniprot id: A0A1P8Q0Q4
names: Subcellular Location Annotation
messages: cell wall

1847728:BTM29 RS10900
gene id: 1847728:BTM29_RS10900
uniprot id: A0A1P8Q5A3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1847728:BTM29 RS12560
gene id: 1847728:BTM29_RS12560
uniprot id: A0A1P8Q6G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1847728:BTM29 RS06825
gene id: 1847728:BTM29_RS06825
uniprot id: A0A1P8Q343
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS05000
gene id: 1847728:BTM29_RS05000
uniprot id: A0A1P8Q248
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1847728:BTM29 RS10095
gene id: 1847728:BTM29_RS10095
uniprot id: A0A1P8Q4V5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1847728:BTM29 RS08510
gene id: 1847728:BTM29_RS08510
uniprot id: A0A1P8Q454
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1847728:BTM29 RS06140
gene id: 1847728:BTM29_RS06140
uniprot id: A0A1P8Q2Q8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1847728:BTM29 RS03945
gene id: 1847728:BTM29_RS03945
uniprot id: A0A1P8Q1U3
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1847728:BTM29 RS02010
gene id: 1847728:BTM29_RS02010
uniprot id: A0A1P8Q0K0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS03220
gene id: 1847728:BTM29_RS03220
uniprot id: A0A1P8Q1C2
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1847728:BTM29 RS07265
gene id: 1847728:BTM29_RS07265
uniprot id: A0A1P8Q3C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1847728:BTM29 RS03830
gene id: 1847728:BTM29_RS03830
uniprot id: A0A1P8Q1N1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1847728:BTM29 RS05050
gene id: 1847728:BTM29_RS05050
uniprot id: A0A1P8Q2A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1847728:BTM29 RS05200
gene id: 1847728:BTM29_RS05200
uniprot id: A0A1P8Q291
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

1847728:BTM29 RS05555
gene id: 1847728:BTM29_RS05555
uniprot id: A0A1P8Q2P0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1847728:BTM29 RS03880
gene id: 1847728:BTM29_RS03880
uniprot id: A0A1P8Q1P1
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

1847728:BTM29 RS03740
gene id: 1847728:BTM29_RS03740
uniprot id: A0A1P8Q1Q2
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS03340
gene id: 1847728:BTM29_RS03340
uniprot id: A0A1P8Q1I4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1847728:BTM29 RS02805
gene id: 1847728:BTM29_RS02805
uniprot id: A0A1P8Q0Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1847728:BTM29 RS09705
gene id: 1847728:BTM29_RS09705
uniprot id: A0A1P8Q4T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1847728:BTM29 RS08485
gene id: 1847728:BTM29_RS08485
uniprot id: A0A1P8Q411
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1847728:BTM29 RS10585
gene id: 1847728:BTM29_RS10585
uniprot id: A0A1P8Q539
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1847728:BTM29 RS05045
gene id: 1847728:BTM29_RS05045
uniprot id: A0A1P8Q261
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1847728:BTM29 RS02795
gene id: 1847728:BTM29_RS02795
uniprot id: A0A1P8Q109
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1847728:BTM29 RS02065
gene id: 1847728:BTM29_RS02065
uniprot id: A0A1P8Q0L1
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1847728:BTM29 RS02365
gene id: 1847728:BTM29_RS02365
uniprot id: A0A1P8Q0Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS12340
gene id: 1847728:BTM29_RS12340
uniprot id: A0A1P8Q601
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS11595
gene id: 1847728:BTM29_RS11595
uniprot id: A0A1P8Q5M5
names: Similarity
messages: Belongs to the peptidase C69 family.

1847728:BTM29 RS10330
gene id: 1847728:BTM29_RS10330
uniprot id: A0A1P8Q523
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1847728:BTM29 RS10385
gene id: 1847728:BTM29_RS10385
uniprot id: A0A1P8Q531
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1847728:BTM29 RS06375
gene id: 1847728:BTM29_RS06375
uniprot id: A0A1P8Q306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS11225
gene id: 1847728:BTM29_RS11225
uniprot id: A0A1P8Q5G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1847728:BTM29 RS00450
gene id: 1847728:BTM29_RS00450
uniprot id: A0A1P8PZY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S15 family.
messages: Cytoplasm
messages: Homodimer.
messages: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

1847728:BTM29 RS00105
gene id: 1847728:BTM29_RS00105
uniprot id: A0A1P8PZQ4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1847728:BTM29 RS04625
gene id: 1847728:BTM29_RS04625
uniprot id: A0A1P8Q1X8
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS04470
gene id: 1847728:BTM29_RS04470
uniprot id: A0A1P8Q1Z5
names: Similarity
messages: Belongs to the peptidase C69 family.

1847728:BTM29 RS12220
gene id: 1847728:BTM29_RS12220
uniprot id: A0A1P8Q5W3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1847728:BTM29 RS02960
gene id: 1847728:BTM29_RS02960
uniprot id: A0A1P8Q183
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1847728:BTM29 RS02785
gene id: 1847728:BTM29_RS02785
uniprot id: A0A1P8Q107
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS02950
gene id: 1847728:BTM29_RS02950
uniprot id: A0A1P8Q1A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1847728:BTM29 RS11135
gene id: 1847728:BTM29_RS11135
uniprot id: A0A1P8Q5G8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS04665
gene id: 1847728:BTM29_RS04665
uniprot id: A0A1P8Q277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1847728:BTM29 RS12320
gene id: 1847728:BTM29_RS12320
uniprot id: A0A1P8Q635
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1847728:BTM29 RS00555
gene id: 1847728:BTM29_RS00555
uniprot id: A0A1P8PZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS11115
gene id: 1847728:BTM29_RS11115
uniprot id: A0A1P8Q5G2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1847728:BTM29 RS06670
gene id: 1847728:BTM29_RS06670
uniprot id: A0A1P8Q314
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1847728:BTM29 RS01935
gene id: 1847728:BTM29_RS01935
uniprot id: A0A1P8Q0J3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1847728:BTM29 RS09750
gene id: 1847728:BTM29_RS09750
uniprot id: A0A1P8Q4N1
names: Subcellular Location Annotation
messages: Cytoplasm

1847728:BTM29 RS08440
gene id: 1847728:BTM29_RS08440
uniprot id: A0A1P8Q3Z9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS03315
gene id: 1847728:BTM29_RS03315
uniprot id: A0A1P8Q1E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1847728:BTM29 RS04480
gene id: 1847728:BTM29_RS04480
uniprot id: A0A1P8Q1X2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1847728:BTM29 RS04030
gene id: 1847728:BTM29_RS04030
uniprot id: A0A1P8Q1S1
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1847728:BTM29 RS04610
gene id: 1847728:BTM29_RS04610
uniprot id: A0A1P8Q1Y0
names: Similarity
messages: Belongs to the universal stress protein A family.

1847728:BTM29 RS02345
gene id: 1847728:BTM29_RS02345
uniprot id: A0A1P8Q0W4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1847728:BTM29 RS07605
gene id: 1847728:BTM29_RS07605
uniprot id: A0A1P8Q3I3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1847728:BTM29 RS10310
gene id: 1847728:BTM29_RS10310
uniprot id: A0A1P8Q4Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1847728:BTM29 RS03630
gene id: 1847728:BTM29_RS03630
uniprot id: A0A1P8Q1N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS09900
gene id: 1847728:BTM29_RS09900
uniprot id: A0A1P8Q4S2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1847728:BTM29 RS03540
gene id: 1847728:BTM29_RS03540
uniprot id: A0A1P8Q1C5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1847728:BTM29 RS11570
gene id: 1847728:BTM29_RS11570
uniprot id: A0A1P8Q5N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1847728:BTM29 RS12605
gene id: 1847728:BTM29_RS12605
uniprot id: A0A1P8Q2G9
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

1847728:BTM29 RS07385
gene id: 1847728:BTM29_RS07385
uniprot id: A0A1P8Q3G0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS00570
gene id: 1847728:BTM29_RS00570
uniprot id: A0A1P8PZT3
names: Similarity
messages: Belongs to the TPP enzyme family.

1847728:BTM29 RS01980
gene id: 1847728:BTM29_RS01980
uniprot id: A0A1P8Q0N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1847728:BTM29 RS11235
gene id: 1847728:BTM29_RS11235
uniprot id: A0A1P8Q5F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1847728:BTM29 RS08580
gene id: 1847728:BTM29_RS08580
uniprot id: A0A1P8Q428
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1847728:BTM29 RS07565
gene id: 1847728:BTM29_RS07565
uniprot id: A0A1P8Q3J2
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1847728:BTM29 RS08445
gene id: 1847728:BTM29_RS08445
uniprot id: A0A1P8Q406
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1847728:BTM29 RS09805
gene id: 1847728:BTM29_RS09805
uniprot id: A0A1P8Q4N0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS10660
gene id: 1847728:BTM29_RS10660
uniprot id: A0A1P8Q544
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1847728:BTM29 RS08475
gene id: 1847728:BTM29_RS08475
uniprot id: A0A1P8Q3Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1847728:BTM29 RS05540
gene id: 1847728:BTM29_RS05540
uniprot id: A0A1P8Q2K4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1847728:BTM29 RS08990
gene id: 1847728:BTM29_RS08990
uniprot id: A0A1P8Q487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1847728:BTM29 RS00050
gene id: 1847728:BTM29_RS00050
uniprot id: A0A1P8PZL0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1847728:BTM29 RS00295
gene id: 1847728:BTM29_RS00295
uniprot id: A0A1P8PZV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

1847728:BTM29 RS00190
gene id: 1847728:BTM29_RS00190
uniprot id: A0A1P8PZL3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1847728:BTM29 RS03620
gene id: 1847728:BTM29_RS03620
uniprot id: A0A1P8Q1J0
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS05975
gene id: 1847728:BTM29_RS05975
uniprot id: A0A1P8Q2N6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1847728:BTM29 RS03675
gene id: 1847728:BTM29_RS03675
uniprot id: A0A1P8Q1K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cell envelope
messages: Releases the N-terminal proline from various substrates.

1847728:BTM29 RS00225
gene id: 1847728:BTM29_RS00225
uniprot id: A0A1P8PZT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1847728:BTM29 RS04675
gene id: 1847728:BTM29_RS04675
uniprot id: A0A1P8Q234
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

1847728:BTM29 RS07040
gene id: 1847728:BTM29_RS07040
uniprot id: A0A1P8Q3A0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1847728:BTM29 RS07670
gene id: 1847728:BTM29_RS07670
uniprot id: A0A1P8Q3J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1847728:BTM29 RS09675
gene id: 1847728:BTM29_RS09675
uniprot id: A0A1P8Q4Q2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS11030
gene id: 1847728:BTM29_RS11030
uniprot id: A0A1P8Q5E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1847728:BTM29 RS01365
gene id: 1847728:BTM29_RS01365
uniprot id: A0A1P8Q0C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1847728:BTM29 RS02865
gene id: 1847728:BTM29_RS02865
uniprot id: A0A1P8Q111
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: Belongs to the CRISPR-associated protein Cas9 family. Subtype II-A subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

1847728:BTM29 RS07190
gene id: 1847728:BTM29_RS07190
uniprot id: A0A1P8Q3D8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1847728:BTM29 RS01395
gene id: 1847728:BTM29_RS01395
uniprot id: A0A1P8Q0D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS10195
gene id: 1847728:BTM29_RS10195
uniprot id: A0A1P8Q4Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1847728:BTM29 RS03930
gene id: 1847728:BTM29_RS03930
uniprot id: A0A1P8Q1Q1
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS07215
gene id: 1847728:BTM29_RS07215
uniprot id: A0A1P8Q3E4
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS09720
gene id: 1847728:BTM29_RS09720
uniprot id: A0A1P8Q4M1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1847728:BTM29 RS06040
gene id: 1847728:BTM29_RS06040
uniprot id: A0A1P8Q2S9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1847728:BTM29 RS07530
gene id: 1847728:BTM29_RS07530
uniprot id: A0A1P8Q697
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1847728:BTM29 RS03275
gene id: 1847728:BTM29_RS03275
uniprot id: A0A1P8Q1C9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1847728:BTM29 RS03435
gene id: 1847728:BTM29_RS03435
uniprot id: A0A1P8Q1G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS08360
gene id: 1847728:BTM29_RS08360
uniprot id: A0A1P8Q3X8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1847728:BTM29 RS04450
gene id: 1847728:BTM29_RS04450
uniprot id: A0A1P8Q1U8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1847728:BTM29 RS09915
gene id: 1847728:BTM29_RS09915
uniprot id: A0A1P8Q4R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1847728:BTM29 RS02110
gene id: 1847728:BTM29_RS02110
uniprot id: A0A1P8Q0S0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1847728:BTM29 RS00670
gene id: 1847728:BTM29_RS00670
uniprot id: A0A1P8PZV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06805
gene id: 1847728:BTM29_RS06805
uniprot id: A0A1P8Q383
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS06830
gene id: 1847728:BTM29_RS06830
uniprot id: A0A1P8Q368
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1847728:BTM29 RS09400
gene id: 1847728:BTM29_RS09400
uniprot id: A0A1P8Q4F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

1847728:BTM29 RS08575
gene id: 1847728:BTM29_RS08575
uniprot id: A0A1P8Q416
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1847728:BTM29 RS09875
gene id: 1847728:BTM29_RS09875
uniprot id: A0A1P8Q6B2
names: Similarity
messages: Belongs to the LOG family.

1847728:BTM29 RS00490
gene id: 1847728:BTM29_RS00490
uniprot id: A0A1P8PZX5
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS08825
gene id: 1847728:BTM29_RS08825
uniprot id: A0A1P8Q4E3
names: Similarity
messages: Belongs to the EamA transporter family.

1847728:BTM29 RS09590
gene id: 1847728:BTM29_RS09590
uniprot id: A0A1P8Q4J7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1847728:BTM29 RS02075
gene id: 1847728:BTM29_RS02075
uniprot id: A0A1P8Q0R6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1847728:BTM29 RS07485
gene id: 1847728:BTM29_RS07485
uniprot id: A0A1P8Q3H0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1847728:BTM29 RS06500
gene id: 1847728:BTM29_RS06500
uniprot id: A0A1P8Q318
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1847728:BTM29 RS09335
gene id: 1847728:BTM29_RS09335
uniprot id: A0A1P8Q4F3
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1847728:BTM29 RS08705
gene id: 1847728:BTM29_RS08705
uniprot id: A0A1P8Q450
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1847728:BTM29 RS01405
gene id: 1847728:BTM29_RS01405
uniprot id: A0A1P8Q0D7
names: Similarity
messages: Belongs to the DltD family.

1847728:BTM29 RS08845
gene id: 1847728:BTM29_RS08845
uniprot id: A0A1P8Q478
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Autophosphorylated.
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1847728:BTM29 RS02875
gene id: 1847728:BTM29_RS02875
uniprot id: A0A1P8Q159
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1847728:BTM29 RS09315
gene id: 1847728:BTM29_RS09315
uniprot id: A0A1P8Q4E8
names: Similarity
messages: Belongs to the universal stress protein A family.

1847728:BTM29 RS11050
gene id: 1847728:BTM29_RS11050
uniprot id: A0A1P8Q5C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06990
gene id: 1847728:BTM29_RS06990
uniprot id: A0A1P8Q394
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1847728:BTM29 RS02920
gene id: 1847728:BTM29_RS02920
uniprot id: A0A1P8Q119
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1847728:BTM29 RS08910
gene id: 1847728:BTM29_RS08910
uniprot id: A0A1P8Q4B5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1847728:BTM29 RS10430
gene id: 1847728:BTM29_RS10430
uniprot id: A0A1P8Q518
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0213 family.
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1847728:BTM29 RS10815
gene id: 1847728:BTM29_RS10815
uniprot id: A0A1P8Q599
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1847728:BTM29 RS07305
gene id: 1847728:BTM29_RS07305
uniprot id: A0A1P8Q3F2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1847728:BTM29 RS06515
gene id: 1847728:BTM29_RS06515
uniprot id: A0A1P8Q2X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS07195
gene id: 1847728:BTM29_RS07195
uniprot id: A0A1P8Q3F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1847728:BTM29 RS06005
gene id: 1847728:BTM29_RS06005
uniprot id: A0A1P8Q2W3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1847728:BTM29 RS09815
gene id: 1847728:BTM29_RS09815
uniprot id: A0A1P8Q4P2
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1847728:BTM29 RS01680
gene id: 1847728:BTM29_RS01680
uniprot id: A0A1P8Q0L5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS00380
gene id: 1847728:BTM29_RS00380
uniprot id: A0A1P8PZU8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1847728:BTM29 RS04335
gene id: 1847728:BTM29_RS04335
uniprot id: A0A1P8Q1X5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS04485
gene id: 1847728:BTM29_RS04485
uniprot id: A0A1P8Q247
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1847728:BTM29 RS05060
gene id: 1847728:BTM29_RS05060
uniprot id: A0A1P8Q259
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1847728:BTM29 RS03215
gene id: 1847728:BTM29_RS03215
uniprot id: A0A1P8Q1B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1847728:BTM29 RS08480
gene id: 1847728:BTM29_RS08480
uniprot id: A0A1P8Q417
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1847728:BTM29 RS01025
gene id: 1847728:BTM29_RS01025
uniprot id: A0A1P8Q021
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1847728:BTM29 RS07235
gene id: 1847728:BTM29_RS07235
uniprot id: A0A1P8Q3E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1847728:BTM29 RS11210
gene id: 1847728:BTM29_RS11210
uniprot id: A0A1P8Q5F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1847728:BTM29 RS08870
gene id: 1847728:BTM29_RS08870
uniprot id: A0A1P8Q485
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1847728:BTM29 RS09635
gene id: 1847728:BTM29_RS09635
uniprot id: A0A1P8Q4M6
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1847728:BTM29 RS03595
gene id: 1847728:BTM29_RS03595
uniprot id: A0A1P8Q1D5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1847728:BTM29 RS00975
gene id: 1847728:BTM29_RS00975
uniprot id: A0A1P8Q011
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS02585
gene id: 1847728:BTM29_RS02585
uniprot id: A0A1P8Q108
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS11650
gene id: 1847728:BTM29_RS11650
uniprot id: A0A1P8Q5N0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1847728:BTM29 RS00605
gene id: 1847728:BTM29_RS00605
uniprot id: A0A1P8PZZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1847728:BTM29 RS08260
gene id: 1847728:BTM29_RS08260
uniprot id: A0A1P8Q3Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1847728:BTM29 RS09520
gene id: 1847728:BTM29_RS09520
uniprot id: A0A1P8Q4M2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1847728:BTM29 RS00690
gene id: 1847728:BTM29_RS00690
uniprot id: A0A1P8Q008
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1847728:BTM29 RS00710
gene id: 1847728:BTM29_RS00710
uniprot id: A0A1P8PZW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1847728:BTM29 RS06775
gene id: 1847728:BTM29_RS06775
uniprot id: A0A1P8Q363
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1847728:BTM29 RS08765
gene id: 1847728:BTM29_RS08765
uniprot id: A0A1P8Q457
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1847728:BTM29 RS08545
gene id: 1847728:BTM29_RS08545
uniprot id: A0A1P8Q422
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1847728:BTM29 RS08295
gene id: 1847728:BTM29_RS08295
uniprot id: A0A1P8Q3W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1847728:BTM29 RS10755
gene id: 1847728:BTM29_RS10755
uniprot id: A0A1P8Q592
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS02175
gene id: 1847728:BTM29_RS02175
uniprot id: A0A1P8Q0N2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1847728:BTM29 RS00125
gene id: 1847728:BTM29_RS00125
uniprot id: A0A1P8PZQ8
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS06415
gene id: 1847728:BTM29_RS06415
uniprot id: A0A1P8Q2V5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1847728:BTM29 RS05205
gene id: 1847728:BTM29_RS05205
uniprot id: A0A1P8Q2D0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1847728:BTM29 RS02380
gene id: 1847728:BTM29_RS02380
uniprot id: A0A1P8Q0R8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS01535
gene id: 1847728:BTM29_RS01535
uniprot id: A0A1P8Q0B5
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS02340
gene id: 1847728:BTM29_RS02340
uniprot id: A0A1P8Q0R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1847728:BTM29 RS00275
gene id: 1847728:BTM29_RS00275
uniprot id: A0A1P8Q620
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1847728:BTM29 RS08340
gene id: 1847728:BTM29_RS08340
uniprot id: A0A1P8Q3X6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1847728:BTM29 RS01095
gene id: 1847728:BTM29_RS01095
uniprot id: A0A1P8Q082
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS10220
gene id: 1847728:BTM29_RS10220
uniprot id: A0A1P8Q503
names: Similarity
messages: Belongs to the UPF0346 family.

1847728:BTM29 RS01665
gene id: 1847728:BTM29_RS01665
uniprot id: A0A1P8Q0H5
names: Subcellular Location Annotation
messages: Cytoplasm

1847728:BTM29 RS09545
gene id: 1847728:BTM29_RS09545
uniprot id: A0A1P8Q4J3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1847728:BTM29 RS10215
gene id: 1847728:BTM29_RS10215
uniprot id: A0A1P8Q4Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1847728:BTM29 RS11260
gene id: 1847728:BTM29_RS11260
uniprot id: A0A1P8Q5I1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1847728:BTM29 RS05255
gene id: 1847728:BTM29_RS05255
uniprot id: A0A1P8Q2D8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a set of proteins in which some residues (ACT_SITE, NP_BIND, REGION and BINDING) are not conserved.

1847728:BTM29 RS00780
gene id: 1847728:BTM29_RS00780
uniprot id: A0A1P8PZX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1847728:BTM29 RS10365
gene id: 1847728:BTM29_RS10365
uniprot id: A0A1P8Q4Z9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS05330
gene id: 1847728:BTM29_RS05330
uniprot id: A0A1P8Q2G2
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1847728:BTM29 RS00735
gene id: 1847728:BTM29_RS00735
uniprot id: A0A1P8PZY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1847728:BTM29 RS01040
gene id: 1847728:BTM29_RS01040
uniprot id: A0A1P8Q075
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

1847728:BTM29 RS09585
gene id: 1847728:BTM29_RS09585
uniprot id: A0A1P8Q4L6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1847728:BTM29 RS05800
gene id: 1847728:BTM29_RS05800
uniprot id: A0A1P8Q2P1
names: Activity Regulation
names: Caution
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1847728:BTM29 RS06525
gene id: 1847728:BTM29_RS06525
uniprot id: A0A1P8Q334
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1847728:BTM29 RS08180
gene id: 1847728:BTM29_RS08180
uniprot id: A0A1P8Q3V6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06520
gene id: 1847728:BTM29_RS06520
uniprot id: A0A1P8Q324
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1847728:BTM29 RS06050
gene id: 1847728:BTM29_RS06050
uniprot id: A0A1P8Q2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS02580
gene id: 1847728:BTM29_RS02580
uniprot id: A0A1P8Q0W8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1847728:BTM29 RS03650
gene id: 1847728:BTM29_RS03650
uniprot id: A0A1P8Q646
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS03860
gene id: 1847728:BTM29_RS03860
uniprot id: A0A1P8Q1I5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1847728:BTM29 RS12540
gene id: 1847728:BTM29_RS12540
uniprot id: A0A1P8Q6F2
names: Similarity
messages: Belongs to the MobA/MobL family.

1847728:BTM29 RS02900
gene id: 1847728:BTM29_RS02900
uniprot id: A0A1P8Q132
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS09600
gene id: 1847728:BTM29_RS09600
uniprot id: A0A1P8Q4K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1847728:BTM29 RS00150
gene id: 1847728:BTM29_RS00150
uniprot id: A0A1P8PZK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

1847728:BTM29 RS10770
gene id: 1847728:BTM29_RS10770
uniprot id: A0A1P8Q578
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1847728:BTM29 RS10325
gene id: 1847728:BTM29_RS10325
uniprot id: A0A1P8Q4Z3
names: Similarity
messages: Belongs to the CvfB family.

1847728:BTM29 RS04370
gene id: 1847728:BTM29_RS04370
uniprot id: A0A1P8Q1Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS03425
gene id: 1847728:BTM29_RS03425
uniprot id: A0A1P8Q1A8
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00045
gene id: 1847728:BTM29_RS00045
uniprot id: A0A1P8PZI2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1847728:BTM29 RS08250
gene id: 1847728:BTM29_RS08250
uniprot id: A0A1P8Q3X1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1847728:BTM29 RS03050
gene id: 1847728:BTM29_RS03050
uniprot id: A0A1P8Q157
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1847728:BTM29 RS00990
gene id: 1847728:BTM29_RS00990
uniprot id: A0A1P8Q067
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS02935
gene id: 1847728:BTM29_RS02935
uniprot id: A0A1P8Q172
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1847728:BTM29 RS08880
gene id: 1847728:BTM29_RS08880
uniprot id: A0A1P8Q472
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1847728:BTM29 RS06985
gene id: 1847728:BTM29_RS06985
uniprot id: A0A1P8Q387
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1847728:BTM29 RS10800
gene id: 1847728:BTM29_RS10800
uniprot id: A0A1P8Q584
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1847728:BTM29 RS10595
gene id: 1847728:BTM29_RS10595
uniprot id: A0A1P8Q535
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1847728:BTM29 RS01710
gene id: 1847728:BTM29_RS01710
uniprot id: A0A1P8Q0E9
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1847728:BTM29 RS00865
gene id: 1847728:BTM29_RS00865
uniprot id: A0A1P8Q057
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1847728:BTM29 RS11090
gene id: 1847728:BTM29_RS11090
uniprot id: A0A1P8Q5F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1847728:BTM29 RS00550
gene id: 1847728:BTM29_RS00550
uniprot id: A0A1P8PZS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1847728:BTM29 RS00835
gene id: 1847728:BTM29_RS00835
uniprot id: A0A1P8Q017
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1847728:BTM29 RS12200
gene id: 1847728:BTM29_RS12200
uniprot id: A0A1P8Q5Y3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS07490
gene id: 1847728:BTM29_RS07490
uniprot id: A0A1P8Q699
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1847728:BTM29 RS08465
gene id: 1847728:BTM29_RS08465
uniprot id: A0A1P8Q3Z7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1847728:BTM29 RS00950
gene id: 1847728:BTM29_RS00950
uniprot id: A0A1P8Q009
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1847728:BTM29 RS04670
gene id: 1847728:BTM29_RS04670
uniprot id: A0A1P8Q1Z4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1847728:BTM29 RS08610
gene id: 1847728:BTM29_RS08610
uniprot id: A0A1P8Q435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1847728:BTM29 RS10495
gene id: 1847728:BTM29_RS10495
uniprot id: A0A1P8Q550
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1847728:BTM29 RS07325
gene id: 1847728:BTM29_RS07325
uniprot id: A0A1P8Q3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1847728:BTM29 RS05340
gene id: 1847728:BTM29_RS05340
uniprot id: A0A1P8Q2D7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1847728:BTM29 RS10860
gene id: 1847728:BTM29_RS10860
uniprot id: A0A1P8Q591
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1847728:BTM29 RS04455
gene id: 1847728:BTM29_RS04455
uniprot id: A0A1P8Q1U7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1847728:BTM29 RS08925
gene id: 1847728:BTM29_RS08925
uniprot id: A0A1P8Q489
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1847728:BTM29 RS09490
gene id: 1847728:BTM29_RS09490
uniprot id: A0A1P8Q4H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1847728:BTM29 RS00935
gene id: 1847728:BTM29_RS00935
uniprot id: A0A1P8Q006
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1847728:BTM29 RS05275
gene id: 1847728:BTM29_RS05275
uniprot id: A0A1P8Q2E1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1847728:BTM29 RS10855
gene id: 1847728:BTM29_RS10855
uniprot id: A0A1P8Q5B8
names: Similarity
messages: Belongs to the peptidase S16 family.

1847728:BTM29 RS08230
gene id: 1847728:BTM29_RS08230
uniprot id: A0A1P8Q3W6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1847728:BTM29 RS08725
gene id: 1847728:BTM29_RS08725
uniprot id: A0A1P8Q452
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1847728:BTM29 RS10200
gene id: 1847728:BTM29_RS10200
uniprot id: A0A1P8Q4W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1847728:BTM29 RS12030
gene id: 1847728:BTM29_RS12030
uniprot id: A0A1P8Q5W2
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS06945
gene id: 1847728:BTM29_RS06945
uniprot id: A0A1P8Q373
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1847728:BTM29 RS07015
gene id: 1847728:BTM29_RS07015
uniprot id: A0A1P8Q397
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS07005
gene id: 1847728:BTM29_RS07005
uniprot id: A0A1P8Q3A1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1847728:BTM29 RS06630
gene id: 1847728:BTM29_RS06630
uniprot id: A0A1P8Q347
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1847728:BTM29 RS09690
gene id: 1847728:BTM29_RS09690
uniprot id: A0A1P8Q4L2
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1847728:BTM29 RS08555
gene id: 1847728:BTM29_RS08555
uniprot id: A0A1P8Q419
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1847728:BTM29 RS07630
gene id: 1847728:BTM29_RS07630
uniprot id: A0A1P8Q689
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS08800
gene id: 1847728:BTM29_RS08800
uniprot id: A0A1P8Q467
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1847728:BTM29 RS04010
gene id: 1847728:BTM29_RS04010
uniprot id: A0A1P8Q1L5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1847728:BTM29 RS01240
gene id: 1847728:BTM29_RS01240
uniprot id: A0A1P8Q062
names: Similarity
messages: Belongs to the DtxR/MntR family.

1847728:BTM29 RS08700
gene id: 1847728:BTM29_RS08700
uniprot id: A0A1P8Q444
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS00115
gene id: 1847728:BTM29_RS00115
uniprot id: A0A1P8PZQ0
names: Similarity
messages: Belongs to the thioredoxin family.

1847728:BTM29 RS02030
gene id: 1847728:BTM29_RS02030
uniprot id: A0A1P8Q0P3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1847728:BTM29 RS00765
gene id: 1847728:BTM29_RS00765
uniprot id: A0A1P8Q036
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1847728:BTM29 RS00610
gene id: 1847728:BTM29_RS00610
uniprot id: A0A1P8PZU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1847728:BTM29 RS03590
gene id: 1847728:BTM29_RS03590
uniprot id: A0A1P8Q1J2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1847728:BTM29 RS00850
gene id: 1847728:BTM29_RS00850
uniprot id: A0A1P8PZZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1847728:BTM29 RS05955
gene id: 1847728:BTM29_RS05955
uniprot id: A0A1P8Q2V3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1847728:BTM29 RS04160
gene id: 1847728:BTM29_RS04160
uniprot id: A0A1P8Q1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1847728:BTM29 RS01345
gene id: 1847728:BTM29_RS01345
uniprot id: A0A1P8Q0C7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS02775
gene id: 1847728:BTM29_RS02775
uniprot id: A0A1P8Q135
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS08590
gene id: 1847728:BTM29_RS08590
uniprot id: A0A1P8Q434
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1847728:BTM29 RS00620
gene id: 1847728:BTM29_RS00620
uniprot id: A0A1P8PZU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS08640
gene id: 1847728:BTM29_RS08640
uniprot id: A0A1P8Q449
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1847728:BTM29 RS07295
gene id: 1847728:BTM29_RS07295
uniprot id: A0A1P8Q3F7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1847728:BTM29 RS01330
gene id: 1847728:BTM29_RS01330
uniprot id: A0A1P8Q0C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS02590
gene id: 1847728:BTM29_RS02590
uniprot id: A0A1P8Q0V9
names: Similarity
messages: Belongs to the peptidase S11 family.

1847728:BTM29 RS07160
gene id: 1847728:BTM29_RS07160
uniprot id: A0A1P8Q3D0
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS04755
gene id: 1847728:BTM29_RS04755
uniprot id: A0A1P8Q246
names: Similarity
messages: Belongs to the TPP enzyme family.

1847728:BTM29 RS07135
gene id: 1847728:BTM29_RS07135
uniprot id: A0A1P8Q3D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1847728:BTM29 RS09615
gene id: 1847728:BTM29_RS09615
uniprot id: A0A1P8Q4J4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Homohexamer.

1847728:BTM29 RS09300
gene id: 1847728:BTM29_RS09300
uniprot id: A0A1P8Q4E1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1847728:BTM29 RS02980
gene id: 1847728:BTM29_RS02980
uniprot id: A0A1P8Q178
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1847728:BTM29 RS00845
gene id: 1847728:BTM29_RS00845
uniprot id: A0A1P8Q041
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1847728:BTM29 RS00720
gene id: 1847728:BTM29_RS00720
uniprot id: A0A1P8PZV9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1847728:BTM29 RS11820
gene id: 1847728:BTM29_RS11820
uniprot id: A0A1P8Q5R3
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS09470
gene id: 1847728:BTM29_RS09470
uniprot id: A0A1P8Q4G3
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1847728:BTM29 RS06155
gene id: 1847728:BTM29_RS06155
uniprot id: A0A1P8Q2P9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1847728:BTM29 RS06715
gene id: 1847728:BTM29_RS06715
uniprot id: A0A1P8Q331
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1847728:BTM29 RS02200
gene id: 1847728:BTM29_RS02200
uniprot id: A0A1P8Q0P2
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1847728:BTM29 RS02790
gene id: 1847728:BTM29_RS02790
uniprot id: A0A1P8Q177
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS01355
gene id: 1847728:BTM29_RS01355
uniprot id: A0A1P8Q0F5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1847728:BTM29 RS09365
gene id: 1847728:BTM29_RS09365
uniprot id: A0A1P8Q4I3
names: Similarity
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Homotetramer.

1847728:BTM29 RS00140
gene id: 1847728:BTM29_RS00140
uniprot id: A0A1P8PZK5
names: Similarity
messages: Belongs to the UPF0297 family.

1847728:BTM29 RS03145
gene id: 1847728:BTM29_RS03145
uniprot id: A0A1P8Q164
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1847728:BTM29 RS10570
gene id: 1847728:BTM29_RS10570
uniprot id: A0A1P8Q576
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS01875
gene id: 1847728:BTM29_RS01875
uniprot id: A0A1P8Q0L4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1847728:BTM29 RS00680
gene id: 1847728:BTM29_RS00680
uniprot id: A0A1P8PZV3
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1847728:BTM29 RS07315
gene id: 1847728:BTM29_RS07315
uniprot id: A0A1P8Q3D5
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS11270
gene id: 1847728:BTM29_RS11270
uniprot id: A0A1P8Q5I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1847728:BTM29 RS11585
gene id: 1847728:BTM29_RS11585
uniprot id: A0A1P8Q5M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS08940
gene id: 1847728:BTM29_RS08940
uniprot id: A0A1P8Q4H1
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS12325
gene id: 1847728:BTM29_RS12325
uniprot id: A0A1P8Q5Z9
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00685
gene id: 1847728:BTM29_RS00685
uniprot id: A0A1P8PZX7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1847728:BTM29 RS05035
gene id: 1847728:BTM29_RS05035
uniprot id: A0A1P8Q275
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS02520
gene id: 1847728:BTM29_RS02520
uniprot id: A0A1P8Q0V7
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00210
gene id: 1847728:BTM29_RS00210
uniprot id: A0A1P8PZS5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1847728:BTM29 RS01655
gene id: 1847728:BTM29_RS01655
uniprot id: A0A1P8Q0E0
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS01660
gene id: 1847728:BTM29_RS01660
uniprot id: A0A1P8Q0I6
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00145
gene id: 1847728:BTM29_RS00145
uniprot id: A0A1P8PZK4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1847728:BTM29 RS08570
gene id: 1847728:BTM29_RS08570
uniprot id: A0A1P8Q469
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1847728:BTM29 RS01850
gene id: 1847728:BTM29_RS01850
uniprot id: A0A1P8Q0M0
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00520
gene id: 1847728:BTM29_RS00520
uniprot id: A0A1P8PZS3
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS10810
gene id: 1847728:BTM29_RS10810
uniprot id: A0A1P8Q580
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1847728:BTM29 RS00230
gene id: 1847728:BTM29_RS00230
uniprot id: A0A1P8PZM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1847728:BTM29 RS00495
gene id: 1847728:BTM29_RS00495
uniprot id: A0A1P8PZR2
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS02855
gene id: 1847728:BTM29_RS02855
uniprot id: A0A1P8Q163
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1847728:BTM29 RS09280
gene id: 1847728:BTM29_RS09280
uniprot id: A0A1P8Q4E2
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1847728:BTM29 RS01400
gene id: 1847728:BTM29_RS01400
uniprot id: A0A1P8Q0C4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1847728:BTM29 RS03230
gene id: 1847728:BTM29_RS03230
uniprot id: A0A1P8Q624
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family. NanA subfamily.
messages: Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
messages: Cytoplasm
messages: Homotetramer.

1847728:BTM29 RS04340
gene id: 1847728:BTM29_RS04340
uniprot id: A0A1P8Q1S2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS05125
gene id: 1847728:BTM29_RS05125
uniprot id: A0A1P8Q2B1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1847728:BTM29 RS00445
gene id: 1847728:BTM29_RS00445
uniprot id: A0A1P8PZR5
names: Similarity
messages: Belongs to the peptidase C1 family.

1847728:BTM29 RS10320
gene id: 1847728:BTM29_RS10320
uniprot id: A0A1P8Q6C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1847728:BTM29 RS01035
gene id: 1847728:BTM29_RS01035
uniprot id: A0A1P8Q024
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS00810
gene id: 1847728:BTM29_RS00810
uniprot id: A0A1P8PZY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1847728:BTM29 RS08175
gene id: 1847728:BTM29_RS08175
uniprot id: A0A1P8Q3V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1847728:BTM29 RS08695
gene id: 1847728:BTM29_RS08695
uniprot id: A0A1P8Q453
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1847728:BTM29 RS06405
gene id: 1847728:BTM29_RS06405
uniprot id: A0A1P8Q2V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1847728:BTM29 RS07025
gene id: 1847728:BTM29_RS07025
uniprot id: A0A1P8Q3C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1847728:BTM29 RS08860
gene id: 1847728:BTM29_RS08860
uniprot id: A0A1P8Q479
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1847728:BTM29 RS03140
gene id: 1847728:BTM29_RS03140
uniprot id: A0A1P8Q1A9
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

1847728:BTM29 RS01380
gene id: 1847728:BTM29_RS01380
uniprot id: A0A1P8Q079
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1847728:BTM29 RS04890
gene id: 1847728:BTM29_RS04890
uniprot id: A0A1P8Q271
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1847728:BTM29 RS00805
gene id: 1847728:BTM29_RS00805
uniprot id: A0A1P8Q054
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1847728:BTM29 RS06555
gene id: 1847728:BTM29_RS06555
uniprot id: A0A1P8Q2Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1847728:BTM29 RS04065
gene id: 1847728:BTM29_RS04065
uniprot id: A0A1P8Q1M5
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS03055
gene id: 1847728:BTM29_RS03055
uniprot id: A0A1P8Q1C7
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1847728:BTM29 RS08775
gene id: 1847728:BTM29_RS08775
uniprot id: A0A1P8Q459
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1847728:BTM29 RS10245
gene id: 1847728:BTM29_RS10245
uniprot id: A0A1P8Q4Y6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1847728:BTM29 RS01360
gene id: 1847728:BTM29_RS01360
uniprot id: A0A1P8Q076
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS10610
gene id: 1847728:BTM29_RS10610
uniprot id: A0A1P8Q541
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1847728:BTM29 RS00715
gene id: 1847728:BTM29_RS00715
uniprot id: A0A1P8Q025
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06355
gene id: 1847728:BTM29_RS06355
uniprot id: A0A1P8Q2V1
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1847728:BTM29 RS11140
gene id: 1847728:BTM29_RS11140
uniprot id: A0A1P8Q5E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1847728:BTM29 RS00370
gene id: 1847728:BTM29_RS00370
uniprot id: A0A1P8PZS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1847728:BTM29 RS02645
gene id: 1847728:BTM29_RS02645
uniprot id: A0A1P8Q0X4
names: Similarity
messages: Belongs to the ParB family.

1847728:BTM29 RS09920
gene id: 1847728:BTM29_RS09920
uniprot id: A0A1P8Q4R9
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1847728:BTM29 RS03635
gene id: 1847728:BTM29_RS03635
uniprot id: A0A1P8Q1G2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1847728:BTM29 RS02635
gene id: 1847728:BTM29_RS02635
uniprot id: A0A1P8Q0X8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1847728:BTM29 RS05535
gene id: 1847728:BTM29_RS05535
uniprot id: A0A1P8Q2J2
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1847728:BTM29 RS07410
gene id: 1847728:BTM29_RS07410
uniprot id: A0A1P8Q688
names: Similarity
messages: Belongs to the DCK/DGK family.

1847728:BTM29 RS12280
gene id: 1847728:BTM29_RS12280
uniprot id: A0A1P8Q604
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1847728:BTM29 RS06340
gene id: 1847728:BTM29_RS06340
uniprot id: A0A1P8Q313
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1847728:BTM29 RS10250
gene id: 1847728:BTM29_RS10250
uniprot id: A0A1P8Q4Z4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS02975
gene id: 1847728:BTM29_RS02975
uniprot id: A0A1P8Q129
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1847728:BTM29 RS11130
gene id: 1847728:BTM29_RS11130
uniprot id: A0A1P8Q5D7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1847728:BTM29 RS02720
gene id: 1847728:BTM29_RS02720
uniprot id: A0A1P8Q124
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1847728:BTM29 RS10945
gene id: 1847728:BTM29_RS10945
uniprot id: A0A1P8Q598
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1847728:BTM29 RS01260
gene id: 1847728:BTM29_RS01260
uniprot id: A0A1P8Q0A9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06850
gene id: 1847728:BTM29_RS06850
uniprot id: A0A1P8Q369
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1847728:BTM29 RS08790
gene id: 1847728:BTM29_RS08790
uniprot id: A0A1P8Q492
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1847728:BTM29 RS02605
gene id: 1847728:BTM29_RS02605
uniprot id: A0A1P8Q113
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1847728:BTM29 RS10280
gene id: 1847728:BTM29_RS10280
uniprot id: A0A1P8Q4Y4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1847728:BTM29 RS10625
gene id: 1847728:BTM29_RS10625
uniprot id: A0A1P8Q559
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1847728:BTM29 RS07390
gene id: 1847728:BTM29_RS07390
uniprot id: A0A1P8Q3G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS04760
gene id: 1847728:BTM29_RS04760
uniprot id: A0A1P8Q264
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1847728:BTM29 RS07065
gene id: 1847728:BTM29_RS07065
uniprot id: A0A1P8Q3A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1847728:BTM29 RS05285
gene id: 1847728:BTM29_RS05285
uniprot id: A0A1P8Q2G0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1847728:BTM29 RS00535
gene id: 1847728:BTM29_RS00535
uniprot id: A0A1P8PZV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS09555
gene id: 1847728:BTM29_RS09555
uniprot id: A0A1P8Q4J0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1847728:BTM29 RS08090
gene id: 1847728:BTM29_RS08090
uniprot id: A0A1P8Q3S9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1847728:BTM29 RS02740
gene id: 1847728:BTM29_RS02740
uniprot id: A0A1P8Q166
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1847728:BTM29 RS12635
gene id: 1847728:BTM29_RS12635
uniprot id: A0A1P8Q6I4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS12015
gene id: 1847728:BTM29_RS12015
uniprot id: A0A1P8Q5U2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS04410
gene id: 1847728:BTM29_RS04410
uniprot id: A0A1P8Q1T7
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS06900
gene id: 1847728:BTM29_RS06900
uniprot id: A0A1P8Q375
names: Similarity
messages: Belongs to the IMPACT family.

1847728:BTM29 RS02320
gene id: 1847728:BTM29_RS02320
uniprot id: A0A1P8Q0R9
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00340
gene id: 1847728:BTM29_RS00340
uniprot id: A0A1P8PZN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1847728:BTM29 RS08375
gene id: 1847728:BTM29_RS08375
uniprot id: A0A1P8Q3Y3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1847728:BTM29 RS01150
gene id: 1847728:BTM29_RS01150
uniprot id: A0A1P8Q091
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1847728:BTM29 RS00375
gene id: 1847728:BTM29_RS00375
uniprot id: A0A1P8PZV2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1847728:BTM29 RS01020
gene id: 1847728:BTM29_RS01020
uniprot id: A0A1P8Q063
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS04970
gene id: 1847728:BTM29_RS04970
uniprot id: A0A1P8Q286
names: Similarity
messages: Belongs to the polypeptide deformylase family.

1847728:BTM29 RS08650
gene id: 1847728:BTM29_RS08650
uniprot id: A0A1P8Q437
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS08220
gene id: 1847728:BTM29_RS08220
uniprot id: A0A1P8Q3V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1847728:BTM29 RS05970
gene id: 1847728:BTM29_RS05970
uniprot id: A0A1P8Q2N0
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1847728:BTM29 RS07770
gene id: 1847728:BTM29_RS07770
uniprot id: A0A1P8Q3L2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1847728:BTM29 RS11195
gene id: 1847728:BTM29_RS11195
uniprot id: A0A1P8Q5E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS04900
gene id: 1847728:BTM29_RS04900
uniprot id: A0A1P8Q230
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1847728:BTM29 RS02800
gene id: 1847728:BTM29_RS02800
uniprot id: A0A1P8Q149
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS09575
gene id: 1847728:BTM29_RS09575
uniprot id: A0A1P8Q4N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1847728:BTM29 RS05905
gene id: 1847728:BTM29_RS05905
uniprot id: A0A1P8Q2R3
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1847728:BTM29 RS03755
gene id: 1847728:BTM29_RS03755
uniprot id: A0A1P8Q1G5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1847728:BTM29 RS03765
gene id: 1847728:BTM29_RS03765
uniprot id: A0A1P8Q1G6
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1847728:BTM29 RS07255
gene id: 1847728:BTM29_RS07255
uniprot id: A0A1P8Q3E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1847728:BTM29 RS08795
gene id: 1847728:BTM29_RS08795
uniprot id: A0A1P8Q690
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1847728:BTM29 RS12145
gene id: 1847728:BTM29_RS12145
uniprot id: A0A1P8Q5Y9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS01495
gene id: 1847728:BTM29_RS01495
uniprot id: A0A1P8Q0F6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1847728:BTM29 RS04765
gene id: 1847728:BTM29_RS04765
uniprot id: A0A1P8Q223
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS06430
gene id: 1847728:BTM29_RS06430
uniprot id: A0A1P8Q322
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1847728:BTM29 RS11065
gene id: 1847728:BTM29_RS11065
uniprot id: A0A1P8Q5C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1847728:BTM29 RS09890
gene id: 1847728:BTM29_RS09890
uniprot id: A0A1P8Q4R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06275
gene id: 1847728:BTM29_RS06275
uniprot id: A0A1P8Q2X6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS02970
gene id: 1847728:BTM29_RS02970
uniprot id: A0A1P8Q131
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1847728:BTM29 RS06410
gene id: 1847728:BTM29_RS06410
uniprot id: A0A1P8Q2W8
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

1847728:BTM29 RS00945
gene id: 1847728:BTM29_RS00945
uniprot id: A0A1P8Q003
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1847728:BTM29 RS04645
gene id: 1847728:BTM29_RS04645
uniprot id: A0A1P8Q222
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1847728:BTM29 RS03155
gene id: 1847728:BTM29_RS03155
uniprot id: A0A1P8Q158
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1847728:BTM29 RS00755
gene id: 1847728:BTM29_RS00755
uniprot id: A0A1P8Q033
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1847728:BTM29 RS10210
gene id: 1847728:BTM29_RS10210
uniprot id: A0A1P8Q6D3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1847728:BTM29 RS11205
gene id: 1847728:BTM29_RS11205
uniprot id: A0A1P8Q5E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1847728:BTM29 RS03560
gene id: 1847728:BTM29_RS03560
uniprot id: A0A1P8Q1I0
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00320
gene id: 1847728:BTM29_RS00320
uniprot id: A0A1P8PZU6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1847728:BTM29 RS00080
gene id: 1847728:BTM29_RS00080
uniprot id: A0A1P8PZR1
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1847728:BTM29 RS09505
gene id: 1847728:BTM29_RS09505
uniprot id: A0A1P8Q4I0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1847728:BTM29 RS06770
gene id: 1847728:BTM29_RS06770
uniprot id: A0A1P8Q335
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1847728:BTM29 RS03900
gene id: 1847728:BTM29_RS03900
uniprot id: A0A1P8Q1K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1847728:BTM29 RS04860
gene id: 1847728:BTM29_RS04860
uniprot id: A0A1P8Q262
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1847728:BTM29 RS01370
gene id: 1847728:BTM29_RS01370
uniprot id: A0A1P8Q632
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1847728:BTM29 RS00100
gene id: 1847728:BTM29_RS00100
uniprot id: A0A1P8PZL8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1847728:BTM29 RS01435
gene id: 1847728:BTM29_RS01435
uniprot id: A0A1P8Q093
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1847728:BTM29 RS00545
gene id: 1847728:BTM29_RS00545
uniprot id: A0A1P8PZY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1847728:BTM29 RS00240
gene id: 1847728:BTM29_RS00240
uniprot id: A0A1P8PZM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1847728:BTM29 RS02235
gene id: 1847728:BTM29_RS02235
uniprot id: A0A1P8Q0U4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1847728:BTM29 RS01010
gene id: 1847728:BTM29_RS01010
uniprot id: A0A1P8Q043
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

1847728:BTM29 RS04250
gene id: 1847728:BTM29_RS04250
uniprot id: A0A1P8Q1Q9
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1847728:BTM29 RS08070
gene id: 1847728:BTM29_RS08070
uniprot id: A0A1P8Q3T0
names: Subcellular Location Annotation
messages: Cytoplasm

1847728:BTM29 RS02700
gene id: 1847728:BTM29_RS02700
uniprot id: A0A1P8Q0Y1
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00890
gene id: 1847728:BTM29_RS00890
uniprot id: A0A1P8Q051
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1847728:BTM29 RS06815
gene id: 1847728:BTM29_RS06815
uniprot id: A0A1P8Q399
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1847728:BTM29 RS10190
gene id: 1847728:BTM29_RS10190
uniprot id: A0A1P8Q4X1
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

1847728:BTM29 RS13120
gene id: 1847728:BTM29_RS13120
uniprot id: A0A1P8Q389
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1847728:BTM29 RS10465
gene id: 1847728:BTM29_RS10465
uniprot id: A0A1P8Q515
names: Subcellular Location Annotation
messages: Cytoplasm

1847728:BTM29 RS08080
gene id: 1847728:BTM29_RS08080
uniprot id: A0A1P8Q3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1847728:BTM29 RS12240
gene id: 1847728:BTM29_RS12240
uniprot id: A0A1P8Q5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1847728:BTM29 RS03935
gene id: 1847728:BTM29_RS03935
uniprot id: A0A1P8Q1Q6
names: Similarity
messages: Belongs to the peptidase C69 family.

1847728:BTM29 RS04140
gene id: 1847728:BTM29_RS04140
uniprot id: A0A1P8Q1N4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1847728:BTM29 RS02995
gene id: 1847728:BTM29_RS02995
uniprot id: A0A1P8Q147
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1847728:BTM29 RS12515
gene id: 1847728:BTM29_RS12515
uniprot id: A0A1P8Q6F7
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1847728:BTM29 RS09500
gene id: 1847728:BTM29_RS09500
uniprot id: A0A1P8Q4H3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1847728:BTM29 RS03295
gene id: 1847728:BTM29_RS03295
uniprot id: A0A1P8Q1E2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1847728:BTM29 RS11230
gene id: 1847728:BTM29_RS11230
uniprot id: A0A1P8Q5G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1847728:BTM29 RS06230
gene id: 1847728:BTM29_RS06230
uniprot id: A0A1P8Q2X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS12260
gene id: 1847728:BTM29_RS12260
uniprot id: A0A1P8Q608
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1847728:BTM29 RS08830
gene id: 1847728:BTM29_RS08830
uniprot id: A0A1P8Q463
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1847728:BTM29 RS02985
gene id: 1847728:BTM29_RS02985
uniprot id: A0A1P8Q175
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1847728:BTM29 RS07370
gene id: 1847728:BTM29_RS07370
uniprot id: A0A1P8Q3F8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1847728:BTM29 RS02240
gene id: 1847728:BTM29_RS02240
uniprot id: A0A1P8Q628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS10420
gene id: 1847728:BTM29_RS10420
uniprot id: A0A1P8Q506
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1847728:BTM29 RS04535
gene id: 1847728:BTM29_RS04535
uniprot id: A0A1P8Q1Y3
names: Similarity
messages: Belongs to the peptidase C59 family.

1847728:BTM29 RS10530
gene id: 1847728:BTM29_RS10530
uniprot id: A0A1P8Q529
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1847728:BTM29 RS10370
gene id: 1847728:BTM29_RS10370
uniprot id: A0A1P8Q4Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1847728:BTM29 RS01475
gene id: 1847728:BTM29_RS01475
uniprot id: A0A1P8Q0F0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1847728:BTM29 RS01635
gene id: 1847728:BTM29_RS01635
uniprot id: A0A1P8Q0H9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06170
gene id: 1847728:BTM29_RS06170
uniprot id: A0A1P8Q2W9
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1847728:BTM29 RS11810
gene id: 1847728:BTM29_RS11810
uniprot id: A0A1P8Q5Q0
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS08805
gene id: 1847728:BTM29_RS08805
uniprot id: A0A1P8Q465
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1847728:BTM29 RS00870
gene id: 1847728:BTM29_RS00870
uniprot id: A0A1P8PZZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1847728:BTM29 RS00020
gene id: 1847728:BTM29_RS00020
uniprot id: A0A1P8PZI5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS12085
gene id: 1847728:BTM29_RS12085
uniprot id: A0A1P8Q5X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1847728:BTM29 RS05965
gene id: 1847728:BTM29_RS05965
uniprot id: A0A1P8Q2S2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1847728:BTM29 RS00480
gene id: 1847728:BTM29_RS00480
uniprot id: A0A1P8PZX3
names: Similarity
messages: Belongs to the UPF0177 family.

1847728:BTM29 RS05290
gene id: 1847728:BTM29_RS05290
uniprot id: A0A1P8Q2C7
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1847728:BTM29 RS03380
gene id: 1847728:BTM29_RS03380
uniprot id: A0A1P8Q1E9
names: Similarity
messages: Belongs to the UPF0177 family.

1847728:BTM29 RS01375
gene id: 1847728:BTM29_RS01375
uniprot id: A0A1P8Q085
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS06680
gene id: 1847728:BTM29_RS06680
uniprot id: A0A1P8Q349
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1847728:BTM29 RS01460
gene id: 1847728:BTM29_RS01460
uniprot id: A0A1P8Q097
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1847728:BTM29 RS12055
gene id: 1847728:BTM29_RS12055
uniprot id: A0A1P8Q5Y1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1847728:BTM29 RS06840
gene id: 1847728:BTM29_RS06840
uniprot id: A0A1P8Q365
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS01915
gene id: 1847728:BTM29_RS01915
uniprot id: A0A1P8Q0I7
names: Similarity
messages: Belongs to the EamA transporter family.

1847728:BTM29 RS11160
gene id: 1847728:BTM29_RS11160
uniprot id: A0A1P8Q5E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1847728:BTM29 RS05910
gene id: 1847728:BTM29_RS05910
uniprot id: A0A1P8Q2M3
names: Subcellular Location Annotation
messages: Cytoplasm

1847728:BTM29 RS03600
gene id: 1847728:BTM29_RS03600
uniprot id: A0A1P8Q1D7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1847728:BTM29 RS05185
gene id: 1847728:BTM29_RS05185
uniprot id: A0A1P8Q2E4
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS09830
gene id: 1847728:BTM29_RS09830
uniprot id: A0A1P8Q4P4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1847728:BTM29 RS08075
gene id: 1847728:BTM29_RS08075
uniprot id: A0A1P8Q3T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1847728:BTM29 RS00425
gene id: 1847728:BTM29_RS00425
uniprot id: A0A1P8PZW5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1847728:BTM29 RS07200
gene id: 1847728:BTM29_RS07200
uniprot id: A0A1P8Q3C5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1847728:BTM29 RS04615
gene id: 1847728:BTM29_RS04615
uniprot id: A0A1P8Q649
names: Similarity
messages: Belongs to the peptidase M13 family.

1847728:BTM29 RS10185
gene id: 1847728:BTM29_RS10185
uniprot id: A0A1P8Q517
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

1847728:BTM29 RS04995
gene id: 1847728:BTM29_RS04995
uniprot id: A0A1P8Q290
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1847728:BTM29 RS00410
gene id: 1847728:BTM29_RS00410
uniprot id: A0A1P8PZQ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1847728:BTM29 RS05360
gene id: 1847728:BTM29_RS05360
uniprot id: A0A1P8Q2B9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS00175
gene id: 1847728:BTM29_RS00175
uniprot id: A0A1P8PZS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1847728:BTM29 RS02560
gene id: 1847728:BTM29_RS02560
uniprot id: A0A1P8Q0Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS01005
gene id: 1847728:BTM29_RS01005
uniprot id: A0A1P8Q013
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1847728:BTM29 RS10395
gene id: 1847728:BTM29_RS10395
uniprot id: A0A1P8Q504
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1847728:BTM29 RS06635
gene id: 1847728:BTM29_RS06635
uniprot id: A0A1P8Q352
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1847728:BTM29 RS00330
gene id: 1847728:BTM29_RS00330
uniprot id: A0A1P8PZN1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1847728:BTM29 RS01885
gene id: 1847728:BTM29_RS01885
uniprot id: A0A1P8Q0I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1847728:BTM29 RS02765
gene id: 1847728:BTM29_RS02765
uniprot id: A0A1P8Q0Y8
names: Similarity
messages: Belongs to the ThiD family.

1847728:BTM29 RS10925
gene id: 1847728:BTM29_RS10925
uniprot id: A0A1P8Q596
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1847728:BTM29 RS07610
gene id: 1847728:BTM29_RS07610
uniprot id: A0A1P8Q3J0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS10845
gene id: 1847728:BTM29_RS10845
uniprot id: A0A1P8Q588
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS09565
gene id: 1847728:BTM29_RS09565
uniprot id: A0A1P8Q4J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1847728:BTM29 RS08760
gene id: 1847728:BTM29_RS08760
uniprot id: A0A1P8Q462
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1847728:BTM29 RS01530
gene id: 1847728:BTM29_RS01530
uniprot id: A0A1P8Q0F9
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS02780
gene id: 1847728:BTM29_RS02780
uniprot id: A0A1P8Q144
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1847728:BTM29 RS02460
gene id: 1847728:BTM29_RS02460
uniprot id: A0A1P8Q0X2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1847728:BTM29 RS07285
gene id: 1847728:BTM29_RS07285
uniprot id: A0A1P8Q3F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1847728:BTM29 RS02020
gene id: 1847728:BTM29_RS02020
uniprot id: A0A1P8Q0K7
names: Similarity
messages: Belongs to the phosphopentomutase family.

1847728:BTM29 RS04060
gene id: 1847728:BTM29_RS04060
uniprot id: A0A1P8Q1S9
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS11845
gene id: 1847728:BTM29_RS11845
uniprot id: A0A1P8Q5U3
names: Similarity
messages: Belongs to the UPF0735 family.

1847728:BTM29 RS08595
gene id: 1847728:BTM29_RS08595
uniprot id: A0A1P8Q430
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1847728:BTM29 RS07045
gene id: 1847728:BTM29_RS07045
uniprot id: A0A1P8Q3A7
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS08155
gene id: 1847728:BTM29_RS08155
uniprot id: A0A1P8Q3T4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1847728:BTM29 RS00165
gene id: 1847728:BTM29_RS00165
uniprot id: A0A1P8PZR3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS11190
gene id: 1847728:BTM29_RS11190
uniprot id: A0A1P8Q5I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1847728:BTM29 RS01015
gene id: 1847728:BTM29_RS01015
uniprot id: A0A1P8Q077
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1847728:BTM29 RS05780
gene id: 1847728:BTM29_RS05780
uniprot id: A0A1P8Q2J7
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1847728:BTM29 RS04520
gene id: 1847728:BTM29_RS04520
uniprot id: A0A1P8Q202
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS07095
gene id: 1847728:BTM29_RS07095
uniprot id: A0A1P8Q3B7
names: PTM
names: Subcellular Location Annotation
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm

1847728:BTM29 RS12090
gene id: 1847728:BTM29_RS12090
uniprot id: A0A1P8Q5X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS10695
gene id: 1847728:BTM29_RS10695
uniprot id: A0A1P8Q6B7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1847728:BTM29 RS02160
gene id: 1847728:BTM29_RS02160
uniprot id: A0A1P8Q0N9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1847728:BTM29 RS04405
gene id: 1847728:BTM29_RS04405
uniprot id: A0A1P8Q1T9
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS08270
gene id: 1847728:BTM29_RS08270
uniprot id: A0A1P8Q3X0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS04305
gene id: 1847728:BTM29_RS04305
uniprot id: A0A1P8Q1W3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1847728:BTM29 RS06920
gene id: 1847728:BTM29_RS06920
uniprot id: A0A1P8Q3A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1847728:BTM29 RS06615
gene id: 1847728:BTM29_RS06615
uniprot id: A0A1P8Q305
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1847728:BTM29 RS06875
gene id: 1847728:BTM29_RS06875
uniprot id: A0A1P8Q3A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1847728:BTM29 RS06295
gene id: 1847728:BTM29_RS06295
uniprot id: A0A1P8Q303
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1847728:BTM29 RS00725
gene id: 1847728:BTM29_RS00725
uniprot id: A0A1P8PZW6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1847728:BTM29 RS06820
gene id: 1847728:BTM29_RS06820
uniprot id: A0A1P8Q681
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1847728:BTM29 RS13060
gene id: 1847728:BTM29_RS13060
uniprot id: A0A1P8Q3G4
names: Function
messages: Required for transformation and DNA binding.

1847728:BTM29 RS01805
gene id: 1847728:BTM29_RS01805
uniprot id: A0A1P8Q0G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1847728:BTM29 RS10575
gene id: 1847728:BTM29_RS10575
uniprot id: A0A1P8Q533
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1847728:BTM29 RS04255
gene id: 1847728:BTM29_RS04255
uniprot id: A0A1P8Q1V3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1847728:BTM29 RS03750
gene id: 1847728:BTM29_RS03750
uniprot id: A0A1P8Q1L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1847728:BTM29 RS03920
gene id: 1847728:BTM29_RS03920
uniprot id: A0A1P8Q1J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1847728:BTM29 RS08310
gene id: 1847728:BTM29_RS08310
uniprot id: A0A1P8Q3Y9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1847728:BTM29 RS05805
gene id: 1847728:BTM29_RS05805
uniprot id: A0A1P8Q2Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS12525
gene id: 1847728:BTM29_RS12525
uniprot id: A0A1P8Q6H1
names: Similarity
messages: Belongs to the zeta toxin family.

1847728:BTM29 RS06575
gene id: 1847728:BTM29_RS06575
uniprot id: A0A1P8Q341
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1847728:BTM29 RS04320
gene id: 1847728:BTM29_RS04320
uniprot id: A0A1P8Q1U2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS08225
gene id: 1847728:BTM29_RS08225
uniprot id: A0A1P8Q3W3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1847728:BTM29 RS10615
gene id: 1847728:BTM29_RS10615
uniprot id: A0A1P8Q536
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1847728:BTM29 RS07625
gene id: 1847728:BTM29_RS07625
uniprot id: A0A1P8Q3K1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS08425
gene id: 1847728:BTM29_RS08425
uniprot id: A0A1P8Q401
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1847728:BTM29 RS04660
gene id: 1847728:BTM29_RS04660
uniprot id: A0A1P8Q203
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00875
gene id: 1847728:BTM29_RS00875
uniprot id: A0A1P8Q001
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1847728:BTM29 RS11040
gene id: 1847728:BTM29_RS11040
uniprot id: A0A1P8Q5D6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS07130
gene id: 1847728:BTM29_RS07130
uniprot id: A0A1P8Q673
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1847728:BTM29 RS03090
gene id: 1847728:BTM29_RS03090
uniprot id: A0A1P8Q154
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06950
gene id: 1847728:BTM29_RS06950
uniprot id: A0A1P8Q390
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1847728:BTM29 RS06890
gene id: 1847728:BTM29_RS06890
uniprot id: A0A1P8Q381
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1847728:BTM29 RS05960
gene id: 1847728:BTM29_RS05960
uniprot id: A0A1P8Q2P3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1847728:BTM29 RS08085
gene id: 1847728:BTM29_RS08085
uniprot id: A0A1P8Q3Y1
names: Similarity
messages: Belongs to the carbamate kinase family.

1847728:BTM29 RS07260
gene id: 1847728:BTM29_RS07260
uniprot id: A0A1P8Q3F1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1847728:BTM29 RS01700
gene id: 1847728:BTM29_RS01700
uniprot id: A0A1P8Q0E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1847728:BTM29 RS04015
gene id: 1847728:BTM29_RS04015
uniprot id: A0A1P8Q1L7
names: Similarity
messages: Belongs to the peptidase C69 family.

1847728:BTM29 RS02145
gene id: 1847728:BTM29_RS02145
uniprot id: A0A1P8Q0S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1847728:BTM29 RS01910
gene id: 1847728:BTM29_RS01910
uniprot id: A0A1P8Q0I0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1847728:BTM29 RS05795
gene id: 1847728:BTM29_RS05795
uniprot id: A0A1P8Q2I8
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1847728:BTM29 RS08530
gene id: 1847728:BTM29_RS08530
uniprot id: A0A1P8Q402
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1847728:BTM29 RS04560
gene id: 1847728:BTM29_RS04560
uniprot id: A0A1P8Q1W6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1847728:BTM29 RS07525
gene id: 1847728:BTM29_RS07525
uniprot id: A0A1P8Q3H6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS06175
gene id: 1847728:BTM29_RS06175
uniprot id: A0A1P8Q2T2
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1847728:BTM29 RS12175
gene id: 1847728:BTM29_RS12175
uniprot id: A0A1P8Q5Y2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1847728:BTM29 RS02470
gene id: 1847728:BTM29_RS02470
uniprot id: A0A1P8Q0U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS08980
gene id: 1847728:BTM29_RS08980
uniprot id: A0A1P8Q4A5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1847728:BTM29 RS00740
gene id: 1847728:BTM29_RS00740
uniprot id: A0A1P8Q016
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1847728:BTM29 RS09910
gene id: 1847728:BTM29_RS09910
uniprot id: A0A1P8Q4T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1847728:BTM29 RS11015
gene id: 1847728:BTM29_RS11015
uniprot id: A0A1P8Q5B9
names: Similarity
messages: Belongs to the YggT family.

1847728:BTM29 RS06955
gene id: 1847728:BTM29_RS06955
uniprot id: A0A1P8Q372
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1847728:BTM29 RS00120
gene id: 1847728:BTM29_RS00120
uniprot id: A0A1P8PZJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1847728:BTM29 RS06425
gene id: 1847728:BTM29_RS06425
uniprot id: A0A1P8Q315
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

1847728:BTM29 RS06625
gene id: 1847728:BTM29_RS06625
uniprot id: A0A1P8Q344
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1847728:BTM29 RS03585
gene id: 1847728:BTM29_RS03585
uniprot id: A0A1P8Q1F3
names: Similarity
messages: Belongs to the aldolase LacD family.

1847728:BTM29 RS06705
gene id: 1847728:BTM29_RS06705
uniprot id: A0A1P8Q350
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS11600
gene id: 1847728:BTM29_RS11600
uniprot id: A0A1P8Q5N9
names: Similarity
messages: Belongs to the UPF0145 family.

1847728:BTM29 RS03960
gene id: 1847728:BTM29_RS03960
uniprot id: A0A1P8Q1K5
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

1847728:BTM29 RS06150
gene id: 1847728:BTM29_RS06150
uniprot id: A0A1P8Q2R6
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS03105
gene id: 1847728:BTM29_RS03105
uniprot id: A0A1P8Q1A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS08645
gene id: 1847728:BTM29_RS08645
uniprot id: A0A1P8Q442
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1847728:BTM29 RS08495
gene id: 1847728:BTM29_RS08495
uniprot id: A0A1P8Q407
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1847728:BTM29 RS02405
gene id: 1847728:BTM29_RS02405
uniprot id: A0A1P8Q0X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06660
gene id: 1847728:BTM29_RS06660
uniprot id: A0A1P8Q348
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS09535
gene id: 1847728:BTM29_RS09535
uniprot id: A0A1P8Q4I1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1847728:BTM29 RS06330
gene id: 1847728:BTM29_RS06330
uniprot id: A0A1P8Q309
names: Similarity
messages: Belongs to the proline racemase family.

1847728:BTM29 RS11625
gene id: 1847728:BTM29_RS11625
uniprot id: A0A1P8Q5P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1847728:BTM29 RS06885
gene id: 1847728:BTM29_RS06885
uniprot id: A0A1P8Q679
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1847728:BTM29 RS10360
gene id: 1847728:BTM29_RS10360
uniprot id: A0A1P8Q512
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1847728:BTM29 RS11070
gene id: 1847728:BTM29_RS11070
uniprot id: A0A1P8Q5C7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1847728:BTM29 RS00630
gene id: 1847728:BTM29_RS00630
uniprot id: A0A1P8PZU2
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1847728:BTM29 RS01125
gene id: 1847728:BTM29_RS01125
uniprot id: A0A1P8Q088
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS05440
gene id: 1847728:BTM29_RS05440
uniprot id: A0A1P8Q2F6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS07125
gene id: 1847728:BTM29_RS07125
uniprot id: A0A1P8Q3D9
names: Similarity
messages: Belongs to the TrpF family.

1847728:BTM29 RS06605
gene id: 1847728:BTM29_RS06605
uniprot id: A0A1P8Q330
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1847728:BTM29 RS11035
gene id: 1847728:BTM29_RS11035
uniprot id: A0A1P8Q5B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

1847728:BTM29 RS03680
gene id: 1847728:BTM29_RS03680
uniprot id: A0A1P8Q1H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1847728:BTM29 RS07575
gene id: 1847728:BTM29_RS07575
uniprot id: A0A1P8Q3I4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1847728:BTM29 RS01685
gene id: 1847728:BTM29_RS01685
uniprot id: A0A1P8Q0E1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1847728:BTM29 RS01690
gene id: 1847728:BTM29_RS01690
uniprot id: A0A1P8Q0J0
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1847728:BTM29 RS03965
gene id: 1847728:BTM29_RS03965
uniprot id: A0A1P8Q1K8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS02890
gene id: 1847728:BTM29_RS02890
uniprot id: A0A1P8Q127
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1847728:BTM29 RS00655
gene id: 1847728:BTM29_RS00655
uniprot id: A0A1P8Q010
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00760
gene id: 1847728:BTM29_RS00760
uniprot id: A0A1P8PZX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1847728:BTM29 RS04705
gene id: 1847728:BTM29_RS04705
uniprot id: A0A1P8Q236
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS08420
gene id: 1847728:BTM29_RS08420
uniprot id: A0A1P8Q405
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1847728:BTM29 RS00785
gene id: 1847728:BTM29_RS00785
uniprot id: A0A1P8Q000
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1847728:BTM29 RS01090
gene id: 1847728:BTM29_RS01090
uniprot id: A0A1P8Q035
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1847728:BTM29 RS00500
gene id: 1847728:BTM29_RS00500
uniprot id: A0A1P8PZX9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1847728:BTM29 RS01890
gene id: 1847728:BTM29_RS01890
uniprot id: A0A1P8Q0Q5
names: Similarity
messages: Belongs to the FBPase class 3 family.

1847728:BTM29 RS09630
gene id: 1847728:BTM29_RS09630
uniprot id: A0A1P8Q4J8
names: Similarity
messages: Belongs to the peptidase C40 family.

1847728:BTM29 RS07035
gene id: 1847728:BTM29_RS07035
uniprot id: A0A1P8Q3D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1847728:BTM29 RS00365
gene id: 1847728:BTM29_RS00365
uniprot id: A0A1P8PZP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1847728:BTM29 RS01065
gene id: 1847728:BTM29_RS01065
uniprot id: A0A1P8Q081
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1847728:BTM29 RS01830
gene id: 1847728:BTM29_RS01830
uniprot id: A0A1P8Q0L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06495
gene id: 1847728:BTM29_RS06495
uniprot id: A0A1P8Q2Y8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1847728:BTM29 RS05405
gene id: 1847728:BTM29_RS05405
uniprot id: A0A1P8Q2G9
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

1847728:BTM29 RS05605
gene id: 1847728:BTM29_RS05605
uniprot id: A0A1P8Q2P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1847728:BTM29 RS02630
gene id: 1847728:BTM29_RS02630
uniprot id: A0A1P8Q146
names: Subcellular Location Annotation
messages: Cell membrane

1847728:BTM29 RS06270
gene id: 1847728:BTM29_RS06270
uniprot id: A0A1P8Q2S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cell envelope
messages: Releases the N-terminal proline from various substrates.

1847728:BTM29 RS10675
gene id: 1847728:BTM29_RS10675
uniprot id: A0A1P8Q545
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1847728:BTM29 RS10265
gene id: 1847728:BTM29_RS10265
uniprot id: A0A1P8Q4Y8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

1847728:BTM29 RS02185
gene id: 1847728:BTM29_RS02185
uniprot id: A0A1P8Q0T4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1847728:BTM29 RS01845
gene id: 1847728:BTM29_RS01845
uniprot id: A0A1P8Q0H0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1847728:BTM29 RS08970
gene id: 1847728:BTM29_RS08970
uniprot id: A0A1P8Q494
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS01735
gene id: 1847728:BTM29_RS01735
uniprot id: A0A1P8Q0M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS01410
gene id: 1847728:BTM29_RS01410
uniprot id: A0A1P8Q092
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1847728:BTM29 RS03890
gene id: 1847728:BTM29_RS03890
uniprot id: A0A1P8Q1L3
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS09525
gene id: 1847728:BTM29_RS09525
uniprot id: A0A1P8Q4H4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS03305
gene id: 1847728:BTM29_RS03305
uniprot id: A0A1P8Q190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS00350
gene id: 1847728:BTM29_RS00350
uniprot id: A0A1P8PZW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1847728:BTM29 RS11390
gene id: 1847728:BTM29_RS11390
uniprot id: A0A1P8Q5L2
names: Similarity
messages: Belongs to the peptidase S14 family.

1847728:BTM29 RS05260
gene id: 1847728:BTM29_RS05260
uniprot id: A0A1P8Q299
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1847728:BTM29 RS03950
gene id: 1847728:BTM29_RS03950
uniprot id: A0A1P8Q1L6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1847728:BTM29 RS00855
gene id: 1847728:BTM29_RS00855
uniprot id: A0A1P8Q072
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1847728:BTM29 RS08330
gene id: 1847728:BTM29_RS08330
uniprot id: A0A1P8Q3Y6
names: Similarity
messages: Belongs to the HesB/IscA family.

1847728:BTM29 RS00460
gene id: 1847728:BTM29_RS00460
uniprot id: A0A1P8PZR6
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS06135
gene id: 1847728:BTM29_RS06135
uniprot id: A0A1P8Q2U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1847728:BTM29 RS11150
gene id: 1847728:BTM29_RS11150
uniprot id: A0A1P8Q5D2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1847728:BTM29 RS12155
gene id: 1847728:BTM29_RS12155
uniprot id: A0A1P8Q5X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS07680
gene id: 1847728:BTM29_RS07680
uniprot id: A0A1P8Q3K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1847728:BTM29 RS06290
gene id: 1847728:BTM29_RS06290
uniprot id: A0A1P8Q2V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS03000
gene id: 1847728:BTM29_RS03000
uniprot id: A0A1P8Q1B7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1847728:BTM29 RS10990
gene id: 1847728:BTM29_RS10990
uniprot id: A0A1P8Q5B3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS03875
gene id: 1847728:BTM29_RS03875
uniprot id: A0A1P8Q1N8
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS00700
gene id: 1847728:BTM29_RS00700
uniprot id: A0A1P8PZV6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS01415
gene id: 1847728:BTM29_RS01415
uniprot id: A0A1P8Q0G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

1847728:BTM29 RS01190
gene id: 1847728:BTM29_RS01190
uniprot id: A0A1P8Q0C3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1847728:BTM29 RS03005
gene id: 1847728:BTM29_RS03005
uniprot id: A0A1P8Q152
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1847728:BTM29 RS05225
gene id: 1847728:BTM29_RS05225
uniprot id: A0A1P8Q2D2
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1847728:BTM29 RS10745
gene id: 1847728:BTM29_RS10745
uniprot id: A0A1P8Q595
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1847728:BTM29 RS00335
gene id: 1847728:BTM29_RS00335
uniprot id: A0A1P8PZU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1847728:BTM29 RS07220
gene id: 1847728:BTM29_RS07220
uniprot id: A0A1P8Q3C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1847728:BTM29 RS00455
gene id: 1847728:BTM29_RS00455
uniprot id: A0A1P8PZR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1847728:BTM29 RS09605
gene id: 1847728:BTM29_RS09605
uniprot id: A0A1P8Q4R8
names: Similarity
messages: Belongs to the CFA/CMAS family.

1847728:BTM29 RS00790
gene id: 1847728:BTM29_RS00790
uniprot id: A0A1P8Q026
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1847728:BTM29 RS08635
gene id: 1847728:BTM29_RS08635
uniprot id: A0A1P8Q421
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1847728:BTM29 RS01555
gene id: 1847728:BTM29_RS01555
uniprot id: A0A1P8Q0F3
names: Similarity
messages: Belongs to the EamA transporter family.

1847728:BTM29 RS02685
gene id: 1847728:BTM29_RS02685
uniprot id: A0A1P8Q0Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1847728:BTM29 RS06995
gene id: 1847728:BTM29_RS06995
uniprot id: A0A1P8Q377
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1847728:BTM29 RS06165
gene id: 1847728:BTM29_RS06165
uniprot id: A0A1P8Q2W4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1847728:BTM29 RS08550
gene id: 1847728:BTM29_RS08550
uniprot id: A0A1P8Q418
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1847728:BTM29 RS12350
gene id: 1847728:BTM29_RS12350
uniprot id: A0A1P8Q603
names: Subcellular Location Annotation
messages: cell wall

1847728:BTM29 RS12600
gene id: 1847728:BTM29_RS12600
uniprot id: A0A1P8Q6G1
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1847728:BTM29 RS10275
gene id: 1847728:BTM29_RS10275
uniprot id: A0A1P8Q4Y1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1847728:BTM29 RS08605
gene id: 1847728:BTM29_RS08605
uniprot id: A0A1P8Q429
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1847728:BTM29 RS03300
gene id: 1847728:BTM29_RS03300
uniprot id: A0A1P8Q189
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS09580
gene id: 1847728:BTM29_RS09580
uniprot id: A0A1P8Q4I8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1847728:BTM29 RS09740
gene id: 1847728:BTM29_RS09740
uniprot id: A0A1P8Q4M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1847728:BTM29 RS01000
gene id: 1847728:BTM29_RS01000
uniprot id: A0A1P8Q019
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1847728:BTM29 RS04710
gene id: 1847728:BTM29_RS04710
uniprot id: A0A1P8Q254
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS10680
gene id: 1847728:BTM29_RS10680
uniprot id: A0A1P8Q569
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1847728:BTM29 RS00750
gene id: 1847728:BTM29_RS00750
uniprot id: A0A1P8PZW0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1847728:BTM29 RS00800
gene id: 1847728:BTM29_RS00800
uniprot id: A0A1P8PZY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1847728:BTM29 RS00200
gene id: 1847728:BTM29_RS00200
uniprot id: A0A1P8PZL6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1847728:BTM29 RS06620
gene id: 1847728:BTM29_RS06620
uniprot id: A0A1P8Q2Z6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1847728:BTM29 RS10875
gene id: 1847728:BTM29_RS10875
uniprot id: A0A1P8Q581
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS06690
gene id: 1847728:BTM29_RS06690
uniprot id: A0A1P8Q356
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1847728:BTM29 RS10670
gene id: 1847728:BTM29_RS10670
uniprot id: A0A1P8Q557
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1847728:BTM29 RS06125
gene id: 1847728:BTM29_RS06125
uniprot id: A0A1P8Q678
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1847728:BTM29 RS09620
gene id: 1847728:BTM29_RS09620
uniprot id: A0A1P8Q4K1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1847728:BTM29 RS01180
gene id: 1847728:BTM29_RS01180
uniprot id: A0A1P8Q099
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS06720
gene id: 1847728:BTM29_RS06720
uniprot id: A0A1P8Q353
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1847728:BTM29 RS08430
gene id: 1847728:BTM29_RS08430
uniprot id: A0A1P8Q3Z4
names: Similarity
messages: Belongs to the asp23 family.

1847728:BTM29 RS08320
gene id: 1847728:BTM29_RS08320
uniprot id: A0A1P8Q3X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1847728:BTM29 RS08585
gene id: 1847728:BTM29_RS08585
uniprot id: A0A1P8Q412
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1847728:BTM29 RS02555
gene id: 1847728:BTM29_RS02555
uniprot id: A0A1P8Q102
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1847728:BTM29 RS11000
gene id: 1847728:BTM29_RS11000
uniprot id: A0A1P8Q5A8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1847728:BTM29 RS08565
gene id: 1847728:BTM29_RS08565
uniprot id: A0A1P8Q414
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1847728:BTM29 RS02680
gene id: 1847728:BTM29_RS02680
uniprot id: A0A1P8Q156
names: Similarity
messages: Belongs to the peptidase C1 family.

1847728:BTM29 RS10545
gene id: 1847728:BTM29_RS10545
uniprot id: A0A1P8Q558
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS06010
gene id: 1847728:BTM29_RS06010
uniprot id: A0A1P8Q2Q0
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS11025
gene id: 1847728:BTM29_RS11025
uniprot id: A0A1P8Q5C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1847728:BTM29 RS01085
gene id: 1847728:BTM29_RS01085
uniprot id: A0A1P8Q0A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1847728:BTM29 RS07650
gene id: 1847728:BTM29_RS07650
uniprot id: A0A1P8Q3J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1847728:BTM29 RS10285
gene id: 1847728:BTM29_RS10285
uniprot id: A0A1P8Q4Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1847728:BTM29 RS03450
gene id: 1847728:BTM29_RS03450
uniprot id: A0A1P8Q1D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS02990
gene id: 1847728:BTM29_RS02990
uniprot id: A0A1P8Q182
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1847728:BTM29 RS02930
gene id: 1847728:BTM29_RS02930
uniprot id: A0A1P8Q165
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1847728:BTM29 RS10975
gene id: 1847728:BTM29_RS10975
uniprot id: A0A1P8Q5A5
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1847728:BTM29 RS08730
gene id: 1847728:BTM29_RS08730
uniprot id: A0A1P8Q447
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1847728:BTM29 RS02425
gene id: 1847728:BTM29_RS02425
uniprot id: A0A1P8Q0T9
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS12235
gene id: 1847728:BTM29_RS12235
uniprot id: A0A1P8Q5Y6
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS06530
gene id: 1847728:BTM29_RS06530
uniprot id: A0A1P8Q333
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-serine, forming acetyl-L-serine.

1847728:BTM29 RS06360
gene id: 1847728:BTM29_RS06360
uniprot id: A0A1P8Q2V7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1847728:BTM29 RS10590
gene id: 1847728:BTM29_RS10590
uniprot id: A0A1P8Q548
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS03555
gene id: 1847728:BTM29_RS03555
uniprot id: A0A1P8Q1H7
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS11005
gene id: 1847728:BTM29_RS11005
uniprot id: A0A1P8Q5E3
names: Subcellular Location Annotation
messages: Cytoplasm

1847728:BTM29 RS10740
gene id: 1847728:BTM29_RS10740
uniprot id: A0A1P8Q575
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1847728:BTM29 RS03010
gene id: 1847728:BTM29_RS03010
uniprot id: A0A1P8Q193
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS10940
gene id: 1847728:BTM29_RS10940
uniprot id: A0A1P8Q5A4
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1847728:BTM29 RS10920
gene id: 1847728:BTM29_RS10920
uniprot id: A0A1P8Q5C9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1847728:BTM29 RS06550
gene id: 1847728:BTM29_RS06550
uniprot id: A0A1P8Q323
names: Similarity
messages: Belongs to the peptidase C59 family.

1847728:BTM29 RS12110
gene id: 1847728:BTM29_RS12110
uniprot id: A0A1P8Q5Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS05915
gene id: 1847728:BTM29_RS05915
uniprot id: A0A1P8Q2M6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS01490
gene id: 1847728:BTM29_RS01490
uniprot id: A0A1P8Q0A7
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1847728:BTM29 RS07020
gene id: 1847728:BTM29_RS07020
uniprot id: A0A1P8Q3A9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1847728:BTM29 RS01420
gene id: 1847728:BTM29_RS01420
uniprot id: A0A1P8Q084
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
messages: Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1847728:BTM29 RS10645
gene id: 1847728:BTM29_RS10645
uniprot id: A0A1P8Q573
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS03810
gene id: 1847728:BTM29_RS03810
uniprot id: A0A1P8Q1H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS10895
gene id: 1847728:BTM29_RS10895
uniprot id: A0A1P8Q5C6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1847728:BTM29 RS11290
gene id: 1847728:BTM29_RS11290
uniprot id: A0A1P8Q5K0
names: Similarity
messages: Belongs to the UPF0177 family.

1847728:BTM29 RS10705
gene id: 1847728:BTM29_RS10705
uniprot id: A0A1P8Q560
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS06975
gene id: 1847728:BTM29_RS06975
uniprot id: A0A1P8Q396
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS07155
gene id: 1847728:BTM29_RS07155
uniprot id: A0A1P8Q3A5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1847728:BTM29 RS02610
gene id: 1847728:BTM29_RS02610
uniprot id: A0A1P8Q104
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1847728:BTM29 RS01920
gene id: 1847728:BTM29_RS01920
uniprot id: A0A1P8Q0N6
names: Similarity
messages: Belongs to the peptidase C69 family.

1847728:BTM29 RS08915
gene id: 1847728:BTM29_RS08915
uniprot id: A0A1P8Q483
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1847728:BTM29 RS00815
gene id: 1847728:BTM29_RS00815
uniprot id: A0A1P8Q049
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1847728:BTM29 RS09420
gene id: 1847728:BTM29_RS09420
uniprot id: A0A1P8Q4J6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1847728:BTM29 RS11575
gene id: 1847728:BTM29_RS11575
uniprot id: A0A1P8Q5L1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS08630
gene id: 1847728:BTM29_RS08630
uniprot id: A0A1P8Q432
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1847728:BTM29 RS10780
gene id: 1847728:BTM29_RS10780
uniprot id: A0A1P8Q5A2
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS06760
gene id: 1847728:BTM29_RS06760
uniprot id: A0A1P8Q361
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

1847728:BTM29 RS00830
gene id: 1847728:BTM29_RS00830
uniprot id: A0A1P8PZY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1847728:BTM29 RS03175
gene id: 1847728:BTM29_RS03175
uniprot id: A0A1P8Q180
names: Similarity
messages: Belongs to the peptidase C40 family.

1847728:BTM29 RS05070
gene id: 1847728:BTM29_RS05070
uniprot id: A0A1P8Q2A1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1847728:BTM29 RS09010
gene id: 1847728:BTM29_RS09010
uniprot id: A0A1P8Q4A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1847728:BTM29 RS06640
gene id: 1847728:BTM29_RS06640
uniprot id: A0A1P8Q345
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1847728:BTM29 RS00300
gene id: 1847728:BTM29_RS00300
uniprot id: A0A1P8PZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1847728:BTM29 RS07515
gene id: 1847728:BTM29_RS07515
uniprot id: A0A1P8Q3H5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1847728:BTM29 RS11110
gene id: 1847728:BTM29_RS11110
uniprot id: A0A1P8Q6F1
names: Similarity
messages: Belongs to the UPF0758 family.

1847728:BTM29 RS07480
gene id: 1847728:BTM29_RS07480
uniprot id: A0A1P8Q3G1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS11835
gene id: 1847728:BTM29_RS11835
uniprot id: A0A1P8Q5R5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS08620
gene id: 1847728:BTM29_RS08620
uniprot id: A0A1P8Q480
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1847728:BTM29 RS06215
gene id: 1847728:BTM29_RS06215
uniprot id: A0A1P8Q2W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1847728:BTM29 RS07690
gene id: 1847728:BTM29_RS07690
uniprot id: A0A1P8Q3L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1847728:BTM29 RS05925
gene id: 1847728:BTM29_RS05925
uniprot id: A0A1P8Q2R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1847728:BTM29 RS10760
gene id: 1847728:BTM29_RS10760
uniprot id: A0A1P8Q562
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1847728:BTM29 RS07115
gene id: 1847728:BTM29_RS07115
uniprot id: A0A1P8Q3B8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1847728:BTM29 RS05845
gene id: 1847728:BTM29_RS05845
uniprot id: A0A1P8Q2L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1847728:BTM29 RS09340
gene id: 1847728:BTM29_RS09340
uniprot id: A0A1P8Q4E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1847728:BTM29 RS08690
gene id: 1847728:BTM29_RS08690
uniprot id: A0A1P8Q461
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1847728:BTM29 RS07495
gene id: 1847728:BTM29_RS07495
uniprot id: A0A1P8Q3H9
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1847728:BTM29 RS01110
gene id: 1847728:BTM29_RS01110
uniprot id: A0A1P8Q030
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1847728:BTM29 RS07140
gene id: 1847728:BTM29_RS07140
uniprot id: A0A1P8Q3F0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1847728:BTM29 RS12190
gene id: 1847728:BTM29_RS12190
uniprot id: A0A1P8Q5W6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1847728:BTM29 RS02330
gene id: 1847728:BTM29_RS02330
uniprot id: A0A1P8Q0Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1847728:BTM29 RS04600
gene id: 1847728:BTM29_RS04600
uniprot id: A0A1P8Q224
names: Similarity
messages: Belongs to the asparagine synthetase family.

1847728:BTM29 RS02165
gene id: 1847728:BTM29_RS02165
uniprot id: A0A1P8Q0T3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1847728:BTM29 RS00930
gene id: 1847728:BTM29_RS00930
uniprot id: A0A1P8Q078
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1847728:BTM29 RS03665
gene id: 1847728:BTM29_RS03665
uniprot id: A0A1P8Q1J9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

1847728:BTM29 RS04945
gene id: 1847728:BTM29_RS04945
uniprot id: A0A1P8Q282
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1847728:BTM29 RS09550
gene id: 1847728:BTM29_RS09550
uniprot id: A0A1P8Q4R4
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1847728:BTM29 RS06895
gene id: 1847728:BTM29_RS06895
uniprot id: A0A1P8Q358
names: Subcellular Location Annotation
messages: Membrane

1847728:BTM29 RS07510
gene id: 1847728:BTM29_RS07510
uniprot id: A0A1P8Q3L5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1847728:BTM29 RS10835
gene id: 1847728:BTM29_RS10835
uniprot id: A0A1P8Q5B5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1847728:BTM29 RS06650
gene id: 1847728:BTM29_RS06650
uniprot id: A0A1P8Q359
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1847728:BTM29 RS11435
gene id: 1847728:BTM29_RS11435
uniprot id: A0A1P8Q2P0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1847728:BTM29 RS02350
gene id: 1847728:BTM29_RS02350
uniprot id: A0A1P8Q0V2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1847728:BTM29 RS08110
gene id: 1847728:BTM29_RS08110
uniprot id: A0A1P8Q3S3
names: Similarity
messages: Belongs to the UPF0342 family.

1847728:BTM29 RS08200
gene id: 1847728:BTM29_RS08200
uniprot id: A0A1P8Q3W2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1847728:BTM29 RS10930
gene id: 1847728:BTM29_RS10930
uniprot id: A0A1P8Q5C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1847728:BTM29 RS01610
gene id: 1847728:BTM29_RS01610
uniprot id: A0A1P8Q0G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1847728:BTM29 RS02655
gene id: 1847728:BTM29_RS02655
uniprot id: A0A1P8Q0W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1847728:BTM29 RS05830
gene id: 1847728:BTM29_RS05830
uniprot id: A0A1P8Q2T4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1847728:BTM29 RS06285
gene id: 1847728:BTM29_RS06285
uniprot id: A0A1P8Q2Z4
names: Similarity
messages: Belongs to the peptidase C69 family.

1847728:BTM29 RS07075
gene id: 1847728:BTM29_RS07075
uniprot id: A0A1P8Q3D3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1847728:BTM29 RS09800
gene id: 1847728:BTM29_RS09800
uniprot id: A0A1P8Q4R2
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1847728:BTM29 RS02535
gene id: 1847728:BTM29_RS02535
uniprot id: A0A1P8Q101
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane