1842532:A7E78 RS13380
gene id: 1842532:A7E78_RS13380
uniprot id: A0A1L3GS69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1842532:A7E78 RS06705
gene id: 1842532:A7E78_RS06705
uniprot id: A0A1L3GNP4
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS05490
gene id: 1842532:A7E78_RS05490
uniprot id: A0A1L3GN15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1842532:A7E78 RS07530
gene id: 1842532:A7E78_RS07530
uniprot id: A0A1L3GP31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1842532:A7E78 RS05800
gene id: 1842532:A7E78_RS05800
uniprot id: A0A1L3GN73
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1842532:A7E78 RS05665
gene id: 1842532:A7E78_RS05665
uniprot id: A0A1L3GN85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1842532:A7E78 RS01455
gene id: 1842532:A7E78_RS01455
uniprot id: A0A1L3GL77
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1842532:A7E78 RS12120
gene id: 1842532:A7E78_RS12120
uniprot id: A0A1L3GRC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1842532:A7E78 RS05915
gene id: 1842532:A7E78_RS05915
uniprot id: A0A1L3GNA4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1842532:A7E78 RS09710
gene id: 1842532:A7E78_RS09710
uniprot id: A0A1L3GQ53
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1842532:A7E78 RS05935
gene id: 1842532:A7E78_RS05935
uniprot id: A0A1L3GN88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1842532:A7E78 RS03270
gene id: 1842532:A7E78_RS03270
uniprot id: A0A1L3GLY6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1842532:A7E78 RS08800
gene id: 1842532:A7E78_RS08800
uniprot id: A0A1L3GPS1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1842532:A7E78 RS13840
gene id: 1842532:A7E78_RS13840
uniprot id: A0A1L3GSY8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1842532:A7E78 RS07565
gene id: 1842532:A7E78_RS07565
uniprot id: A0A1L3GP26
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1842532:A7E78 RS11185
gene id: 1842532:A7E78_RS11185
uniprot id: A0A1L3GQW7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Membrane

1842532:A7E78 RS04520
gene id: 1842532:A7E78_RS04520
uniprot id: A0A1L3GMJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1842532:A7E78 RS11655
gene id: 1842532:A7E78_RS11655
uniprot id: A0A1L3GR83
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS11870
gene id: 1842532:A7E78_RS11870
uniprot id: A0A1L3GRI2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1842532:A7E78 RS10425
gene id: 1842532:A7E78_RS10425
uniprot id: A0A1L3GQM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1842532:A7E78 RS08165
gene id: 1842532:A7E78_RS08165
uniprot id: A0A1L3GPH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1842532:A7E78 RS00585
gene id: 1842532:A7E78_RS00585
uniprot id: A0A1L3GKQ5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1842532:A7E78 RS11735
gene id: 1842532:A7E78_RS11735
uniprot id: A0A1L3GR88
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1842532:A7E78 RS02460
gene id: 1842532:A7E78_RS02460
uniprot id: A0A1L3GLP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1842532:A7E78 RS00970
gene id: 1842532:A7E78_RS00970
uniprot id: A0A1L3GSR1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1842532:A7E78 RS14095
gene id: 1842532:A7E78_RS14095
uniprot id: A0A1L3GSA5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1842532:A7E78 RS12245
gene id: 1842532:A7E78_RS12245
uniprot id: A0A1L3GRF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS02475
gene id: 1842532:A7E78_RS02475
uniprot id: A0A1L3GSQ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1842532:A7E78 RS05590
gene id: 1842532:A7E78_RS05590
uniprot id: A0A1L3GNU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1842532:A7E78 RS02595
gene id: 1842532:A7E78_RS02595
uniprot id: A0A1L3GMC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1842532:A7E78 RS03165
gene id: 1842532:A7E78_RS03165
uniprot id: A0A1L3GMM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS01535
gene id: 1842532:A7E78_RS01535
uniprot id: A0A1L3GL57
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS01830
gene id: 1842532:A7E78_RS01830
uniprot id: A0A1L3GL80
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1842532:A7E78 RS09440
gene id: 1842532:A7E78_RS09440
uniprot id: A0A1L3GQU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1842532:A7E78 RS12140
gene id: 1842532:A7E78_RS12140
uniprot id: A0A1L3GRD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1842532:A7E78 RS14070
gene id: 1842532:A7E78_RS14070
uniprot id: A0A1L3GSC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1842532:A7E78 RS02775
gene id: 1842532:A7E78_RS02775
uniprot id: A0A1L3GLQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1842532:A7E78 RS14295
gene id: 1842532:A7E78_RS14295
uniprot id: A0A1L3GSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1842532:A7E78 RS06580
gene id: 1842532:A7E78_RS06580
uniprot id: A0A1L3GNN5
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS06125
gene id: 1842532:A7E78_RS06125
uniprot id: A0A1L3GNC3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1842532:A7E78 RS07525
gene id: 1842532:A7E78_RS07525
uniprot id: A0A1L3GP38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1842532:A7E78 RS11015
gene id: 1842532:A7E78_RS11015
uniprot id: A0A1L3GRM4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS05740
gene id: 1842532:A7E78_RS05740
uniprot id: A0A1L3GN53
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS01645
gene id: 1842532:A7E78_RS01645
uniprot id: A0A1L3GTF9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1842532:A7E78 RS07850
gene id: 1842532:A7E78_RS07850
uniprot id: A0A1L3GP83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS01310
gene id: 1842532:A7E78_RS01310
uniprot id: A0A1L3GL33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1842532:A7E78 RS12600
gene id: 1842532:A7E78_RS12600
uniprot id: A0A1L3GRL7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1842532:A7E78 RS05810
gene id: 1842532:A7E78_RS05810
uniprot id: A0A1L3GN81
names: Similarity
messages: Belongs to the TlyA family.

1842532:A7E78 RS05565
gene id: 1842532:A7E78_RS05565
uniprot id: A0A1L3GN24
names: Similarity
messages: Belongs to the FlgM family.

1842532:A7E78 RS04935
gene id: 1842532:A7E78_RS04935
uniprot id: A0A1L3GMQ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS07545
gene id: 1842532:A7E78_RS07545
uniprot id: A0A1L3GP71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1842532:A7E78 RS03485
gene id: 1842532:A7E78_RS03485
uniprot id: A0A1L3GM49
names: Similarity
messages: Belongs to the bacterial secretin family.

1842532:A7E78 RS07480
gene id: 1842532:A7E78_RS07480
uniprot id: A0A1L3GP32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1842532:A7E78 RS09205
gene id: 1842532:A7E78_RS09205
uniprot id: A0A1L3GPW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1842532:A7E78 RS07405
gene id: 1842532:A7E78_RS07405
uniprot id: A0A1L3GP22
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1842532:A7E78 RS04525
gene id: 1842532:A7E78_RS04525
uniprot id: A0A1L3GMN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1842532:A7E78 RS02550
gene id: 1842532:A7E78_RS02550
uniprot id: A0A1L3GLQ3
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1842532:A7E78 RS12505
gene id: 1842532:A7E78_RS12505
uniprot id: A0A1L3GRM5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1842532:A7E78 RS04180
gene id: 1842532:A7E78_RS04180
uniprot id: A0A1L3GME0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS03370
gene id: 1842532:A7E78_RS03370
uniprot id: A0A1L3GLZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1842532:A7E78 RS08760
gene id: 1842532:A7E78_RS08760
uniprot id: A0A1L3GPN6
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS05555
gene id: 1842532:A7E78_RS05555
uniprot id: A0A1L3GSX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1842532:A7E78 RS04730
gene id: 1842532:A7E78_RS04730
uniprot id: A0A1L3GMM5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1842532:A7E78 RS08660
gene id: 1842532:A7E78_RS08660
uniprot id: A0A1L3GPL5
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1842532:A7E78 RS08010
gene id: 1842532:A7E78_RS08010
uniprot id: A0A1L3GPD9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1842532:A7E78 RS00665
gene id: 1842532:A7E78_RS00665
uniprot id: A0A1L3GKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1842532:A7E78 RS02125
gene id: 1842532:A7E78_RS02125
uniprot id: A0A1L3GLD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1842532:A7E78 RS08000
gene id: 1842532:A7E78_RS08000
uniprot id: A0A1L3GPC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1842532:A7E78 RS07470
gene id: 1842532:A7E78_RS07470
uniprot id: A0A1L3GP28
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1842532:A7E78 RS14320
gene id: 1842532:A7E78_RS14320
uniprot id: A0A1L3GSE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS12105
gene id: 1842532:A7E78_RS12105
uniprot id: A0A1L3GRD3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS01230
gene id: 1842532:A7E78_RS01230
uniprot id: A0A1L3GL31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1842532:A7E78 RS12775
gene id: 1842532:A7E78_RS12775
uniprot id: A0A1L3GRP2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1842532:A7E78 RS01840
gene id: 1842532:A7E78_RS01840
uniprot id: A0A1L3GL85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1842532:A7E78 RS06855
gene id: 1842532:A7E78_RS06855
uniprot id: A0A1L3GSZ4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1842532:A7E78 RS14155
gene id: 1842532:A7E78_RS14155
uniprot id: A0A1L3GSC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Membrane

1842532:A7E78 RS04285
gene id: 1842532:A7E78_RS04285
uniprot id: A0A1L3GMI8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1842532:A7E78 RS03415
gene id: 1842532:A7E78_RS03415
uniprot id: A0A1L3GLZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1842532:A7E78 RS11315
gene id: 1842532:A7E78_RS11315
uniprot id: A0A1L3GQZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1842532:A7E78 RS04265
gene id: 1842532:A7E78_RS04265
uniprot id: A0A1L3GN65
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1842532:A7E78 RS06110
gene id: 1842532:A7E78_RS06110
uniprot id: A0A1L3GNH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1842532:A7E78 RS12640
gene id: 1842532:A7E78_RS12640
uniprot id: A0A1L3GRL6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1842532:A7E78 RS12810
gene id: 1842532:A7E78_RS12810
uniprot id: A0A1L3GRS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1842532:A7E78 RS14300
gene id: 1842532:A7E78_RS14300
uniprot id: A0A1L3GSH0
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS01260
gene id: 1842532:A7E78_RS01260
uniprot id: A0A1L3GKZ2
names: Similarity
messages: Belongs to the sigma-54 factor family.

1842532:A7E78 RS01875
gene id: 1842532:A7E78_RS01875
uniprot id: A0A1L3GLB5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1842532:A7E78 RS10950
gene id: 1842532:A7E78_RS10950
uniprot id: A0A1L3GQS0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1842532:A7E78 RS01300
gene id: 1842532:A7E78_RS01300
uniprot id: A0A1L3GL12
names: Subcellular Location Annotation
messages: Cytoplasm

1842532:A7E78 RS08290
gene id: 1842532:A7E78_RS08290
uniprot id: A0A1L3GPF2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1842532:A7E78 RS01375
gene id: 1842532:A7E78_RS01375
uniprot id: A0A1L3GLS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1842532:A7E78 RS10180
gene id: 1842532:A7E78_RS10180
uniprot id: A0A1L3GQM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1842532:A7E78 RS00360
gene id: 1842532:A7E78_RS00360
uniprot id: A0A1L3GKL8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1842532:A7E78 RS07550
gene id: 1842532:A7E78_RS07550
uniprot id: A0A1L3GP09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1842532:A7E78 RS11700
gene id: 1842532:A7E78_RS11700
uniprot id: A0A1L3GR52
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS13455
gene id: 1842532:A7E78_RS13455
uniprot id: A0A1L3GS14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1842532:A7E78 RS14350
gene id: 1842532:A7E78_RS14350
uniprot id: A0A1L3GSM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1842532:A7E78 RS14360
gene id: 1842532:A7E78_RS14360
uniprot id: A0A1L3GSI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1842532:A7E78 RS01340
gene id: 1842532:A7E78_RS01340
uniprot id: A0A1L3GL53
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS05520
gene id: 1842532:A7E78_RS05520
uniprot id: A0A1L3GN79
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

1842532:A7E78 RS03965
gene id: 1842532:A7E78_RS03965
uniprot id: A0A1L3GM94
names: Similarity
messages: Belongs to the glutamate synthase family.

1842532:A7E78 RS06210
gene id: 1842532:A7E78_RS06210
uniprot id: A0A1L3GND2
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1842532:A7E78 RS08865
gene id: 1842532:A7E78_RS08865
uniprot id: A0A1L3GPR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1842532:A7E78 RS03170
gene id: 1842532:A7E78_RS03170
uniprot id: A0A1L3GLW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1842532:A7E78 RS04880
gene id: 1842532:A7E78_RS04880
uniprot id: A0A1L3GMU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1842532:A7E78 RS12110
gene id: 1842532:A7E78_RS12110
uniprot id: A0A1L3GTL4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1842532:A7E78 RS04990
gene id: 1842532:A7E78_RS04990
uniprot id: A0A1L3GMR8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1842532:A7E78 RS15530
gene id: 1842532:A7E78_RS15530
uniprot id: A0A1L3GNT8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1842532:A7E78 RS00490
gene id: 1842532:A7E78_RS00490
uniprot id: A0A1L3GKR4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1842532:A7E78 RS12275
gene id: 1842532:A7E78_RS12275
uniprot id: A0A1L3GRI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1842532:A7E78 RS03375
gene id: 1842532:A7E78_RS03375
uniprot id: A0A1L3GM32
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1842532:A7E78 RS02875
gene id: 1842532:A7E78_RS02875
uniprot id: A0A1L3GLR4
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1842532:A7E78 RS04280
gene id: 1842532:A7E78_RS04280
uniprot id: A0A1L3GSX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1842532:A7E78 RS05285
gene id: 1842532:A7E78_RS05285
uniprot id: A0A1L3GN07
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1842532:A7E78 RS08740
gene id: 1842532:A7E78_RS08740
uniprot id: A0A1L3GPR1
names: Caution
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS04125
gene id: 1842532:A7E78_RS04125
uniprot id: A0A1L3GMC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1842532:A7E78 RS10175
gene id: 1842532:A7E78_RS10175
uniprot id: A0A1L3GQD3
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS08225
gene id: 1842532:A7E78_RS08225
uniprot id: A0A1L3GPE1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS07605
gene id: 1842532:A7E78_RS07605
uniprot id: A0A1L3GP29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1842532:A7E78 RS05280
gene id: 1842532:A7E78_RS05280
uniprot id: A0A1L3GN22
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1842532:A7E78 RS12695
gene id: 1842532:A7E78_RS12695
uniprot id: A0A1L3GRN4
names: Similarity
messages: Belongs to the UPF0235 family.

1842532:A7E78 RS00395
gene id: 1842532:A7E78_RS00395
uniprot id: A0A1L3GLC0
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1842532:A7E78 RS10385
gene id: 1842532:A7E78_RS10385
uniprot id: A0A1L3GQI0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1842532:A7E78 RS12045
gene id: 1842532:A7E78_RS12045
uniprot id: A0A1L3GRE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1842532:A7E78 RS10990
gene id: 1842532:A7E78_RS10990
uniprot id: A0A1L3GQW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1842532:A7E78 RS14080
gene id: 1842532:A7E78_RS14080
uniprot id: A0A1L3GSD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1842532:A7E78 RS10985
gene id: 1842532:A7E78_RS10985
uniprot id: A0A1L3GQW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1842532:A7E78 RS12785
gene id: 1842532:A7E78_RS12785
uniprot id: A0A1L3GSH4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1842532:A7E78 RS00675
gene id: 1842532:A7E78_RS00675
uniprot id: A0A1L3GKU0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1842532:A7E78 RS00225
gene id: 1842532:A7E78_RS00225
uniprot id: A0A1L3GKH6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1842532:A7E78 RS00275
gene id: 1842532:A7E78_RS00275
uniprot id: A0A1L3GKI9
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS05925
gene id: 1842532:A7E78_RS05925
uniprot id: A0A1L3GNA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS04230
gene id: 1842532:A7E78_RS04230
uniprot id: A0A1L3GMI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS13450
gene id: 1842532:A7E78_RS13450
uniprot id: A0A1L3GS12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS07490
gene id: 1842532:A7E78_RS07490
uniprot id: A0A1L3GNZ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1842532:A7E78 RS05155
gene id: 1842532:A7E78_RS05155
uniprot id: A0A1L3GNL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1842532:A7E78 RS07825
gene id: 1842532:A7E78_RS07825
uniprot id: A0A1L3GP88
names: Similarity
messages: Belongs to the ModE family.

1842532:A7E78 RS05195
gene id: 1842532:A7E78_RS05195
uniprot id: A0A1L3GMV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1842532:A7E78 RS09155
gene id: 1842532:A7E78_RS09155
uniprot id: A0A1L3GQ28
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1842532:A7E78 RS05930
gene id: 1842532:A7E78_RS05930
uniprot id: A0A1L3GNE7
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1842532:A7E78 RS09405
gene id: 1842532:A7E78_RS09405
uniprot id: A0A1L3GQ06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1842532:A7E78 RS12770
gene id: 1842532:A7E78_RS12770
uniprot id: A0A1L3GRT7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1842532:A7E78 RS01060
gene id: 1842532:A7E78_RS01060
uniprot id: A0A1L3GKW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1842532:A7E78 RS01730
gene id: 1842532:A7E78_RS01730
uniprot id: A0A1L3GLB4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1842532:A7E78 RS00555
gene id: 1842532:A7E78_RS00555
uniprot id: A0A1L3GKM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1842532:A7E78 RS02700
gene id: 1842532:A7E78_RS02700
uniprot id: A0A1L3GLM5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1842532:A7E78 RS09720
gene id: 1842532:A7E78_RS09720
uniprot id: A0A1L3GQ42
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1842532:A7E78 RS14000
gene id: 1842532:A7E78_RS14000
uniprot id: A0A1L3GSE2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1842532:A7E78 RS07905
gene id: 1842532:A7E78_RS07905
uniprot id: A0A1L3GP76
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS12125
gene id: 1842532:A7E78_RS12125
uniprot id: A0A1L3GRE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1842532:A7E78 RS11095
gene id: 1842532:A7E78_RS11095
uniprot id: A0A1L3GQX5
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS09005
gene id: 1842532:A7E78_RS09005
uniprot id: A0A1L3GPT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1842532:A7E78 RS11540
gene id: 1842532:A7E78_RS11540
uniprot id: A0A1L3GR21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1842532:A7E78 RS05420
gene id: 1842532:A7E78_RS05420
uniprot id: A0A1L3GN02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1842532:A7E78 RS14145
gene id: 1842532:A7E78_RS14145
uniprot id: A0A1L3GSB4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1842532:A7E78 RS09460
gene id: 1842532:A7E78_RS09460
uniprot id: A0A1L3GQ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1842532:A7E78 RS11340
gene id: 1842532:A7E78_RS11340
uniprot id: A0A1L3GR17
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS04245
gene id: 1842532:A7E78_RS04245
uniprot id: A0A1L3GME7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS09390
gene id: 1842532:A7E78_RS09390
uniprot id: A0A1L3GPY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1842532:A7E78 RS14325
gene id: 1842532:A7E78_RS14325
uniprot id: A0A1L3GSK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1842532:A7E78 RS01025
gene id: 1842532:A7E78_RS01025
uniprot id: A0A1L3GKT5
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

1842532:A7E78 RS11730
gene id: 1842532:A7E78_RS11730
uniprot id: A0A1L3GT32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1842532:A7E78 RS14150
gene id: 1842532:A7E78_RS14150
uniprot id: A0A1L3GSH2
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS07090
gene id: 1842532:A7E78_RS07090
uniprot id: A0A1L3GNV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1842532:A7E78 RS07595
gene id: 1842532:A7E78_RS07595
uniprot id: A0A1L3GP78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1842532:A7E78 RS10280
gene id: 1842532:A7E78_RS10280
uniprot id: A0A1L3GRA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1842532:A7E78 RS12870
gene id: 1842532:A7E78_RS12870
uniprot id: A0A1L3GT52
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1842532:A7E78 RS10245
gene id: 1842532:A7E78_RS10245
uniprot id: A0A1L3GQG1
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

1842532:A7E78 RS02405
gene id: 1842532:A7E78_RS02405
uniprot id: A0A1L3GLN3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1842532:A7E78 RS10785
gene id: 1842532:A7E78_RS10785
uniprot id: A0A1L3GQR6
names: Similarity
messages: Belongs to the UPF0234 family.

1842532:A7E78 RS10110
gene id: 1842532:A7E78_RS10110
uniprot id: A0A1L3GQB6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1842532:A7E78 RS08700
gene id: 1842532:A7E78_RS08700
uniprot id: A0A1L3GPQ6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1842532:A7E78 RS10720
gene id: 1842532:A7E78_RS10720
uniprot id: A0A1L3GQM3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1842532:A7E78 RS03095
gene id: 1842532:A7E78_RS03095
uniprot id: A0A1L3GLT0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1842532:A7E78 RS01185
gene id: 1842532:A7E78_RS01185
uniprot id: A0A1L3GKZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1842532:A7E78 RS05975
gene id: 1842532:A7E78_RS05975
uniprot id: A0A1L3GN97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS05470
gene id: 1842532:A7E78_RS05470
uniprot id: A0A1L3GN11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1842532:A7E78 RS07250
gene id: 1842532:A7E78_RS07250
uniprot id: A0A1L3GNY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1842532:A7E78 RS05495
gene id: 1842532:A7E78_RS05495
uniprot id: A0A1L3GN61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1842532:A7E78 RS14270
gene id: 1842532:A7E78_RS14270
uniprot id: A0A1L3GSE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1842532:A7E78 RS09560
gene id: 1842532:A7E78_RS09560
uniprot id: A0A1L3GQA2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1842532:A7E78 RS03235
gene id: 1842532:A7E78_RS03235
uniprot id: A0A1L3GLW9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1842532:A7E78 RS11370
gene id: 1842532:A7E78_RS11370
uniprot id: A0A1L3GR39
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1842532:A7E78 RS09840
gene id: 1842532:A7E78_RS09840
uniprot id: A0A1L3GQB9
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS13045
gene id: 1842532:A7E78_RS13045
uniprot id: A0A1L3GRU2
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS13645
gene id: 1842532:A7E78_RS13645
uniprot id: A0A1L3GS26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1842532:A7E78 RS11795
gene id: 1842532:A7E78_RS11795
uniprot id: A0A1L3GR95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS05370
gene id: 1842532:A7E78_RS05370
uniprot id: A0A1L3GNQ2
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1842532:A7E78 RS05310
gene id: 1842532:A7E78_RS05310
uniprot id: A0A1L3GMX6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1842532:A7E78 RS03035
gene id: 1842532:A7E78_RS03035
uniprot id: A0A1L3GLS5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1842532:A7E78 RS11850
gene id: 1842532:A7E78_RS11850
uniprot id: A0A1L3GS22
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1842532:A7E78 RS05985
gene id: 1842532:A7E78_RS05985
uniprot id: A0A1L3GNG1
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1842532:A7E78 RS11805
gene id: 1842532:A7E78_RS11805
uniprot id: A0A1L3GR78
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1842532:A7E78 RS01650
gene id: 1842532:A7E78_RS01650
uniprot id: A0A1L3GL91
names: Similarity
messages: Belongs to the RutC family.

1842532:A7E78 RS09110
gene id: 1842532:A7E78_RS09110
uniprot id: A0A1L3GPT8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1842532:A7E78 RS11545
gene id: 1842532:A7E78_RS11545
uniprot id: A0A1L3GR34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1842532:A7E78 RS14005
gene id: 1842532:A7E78_RS14005
uniprot id: A0A1L3GS90
names: Similarity
messages: Belongs to the CinA family.

1842532:A7E78 RS15395
gene id: 1842532:A7E78_RS15395
uniprot id: A0A1L3GPN8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1842532:A7E78 RS10480
gene id: 1842532:A7E78_RS10480
uniprot id: A0A1L3GQL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1842532:A7E78 RS08805
gene id: 1842532:A7E78_RS08805
uniprot id: A0A1L3GPN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1842532:A7E78 RS06055
gene id: 1842532:A7E78_RS06055
uniprot id: A0A1L3GNB5
names: Similarity
messages: Belongs to the peptidase S16 family.

1842532:A7E78 RS11980
gene id: 1842532:A7E78_RS11980
uniprot id: A0A1L3GRB3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1842532:A7E78 RS09105
gene id: 1842532:A7E78_RS09105
uniprot id: A0A1L3GQ17
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1842532:A7E78 RS09190
gene id: 1842532:A7E78_RS09190
uniprot id: A0A1L3GPV4
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1842532:A7E78 RS10045
gene id: 1842532:A7E78_RS10045
uniprot id: A0A1L3GQD2
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1842532:A7E78 RS01945
gene id: 1842532:A7E78_RS01945
uniprot id: A0A1L3GM21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS09140
gene id: 1842532:A7E78_RS09140
uniprot id: A0A1L3GPV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1842532:A7E78 RS13915
gene id: 1842532:A7E78_RS13915
uniprot id: A0A1L3GSF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1842532:A7E78 RS10930
gene id: 1842532:A7E78_RS10930
uniprot id: A0A1L3GQS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS01685
gene id: 1842532:A7E78_RS01685
uniprot id: A0A1L3GL83
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1842532:A7E78 RS05675
gene id: 1842532:A7E78_RS05675
uniprot id: A0A1L3GN56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1842532:A7E78 RS10510
gene id: 1842532:A7E78_RS10510
uniprot id: A0A1L3GRD8
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

1842532:A7E78 RS06170
gene id: 1842532:A7E78_RS06170
uniprot id: A0A1L3GP45
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS12715
gene id: 1842532:A7E78_RS12715
uniprot id: A0A1L3GRN3
names: Similarity
messages: Belongs to the UPF0047 family.

1842532:A7E78 RS13575
gene id: 1842532:A7E78_RS13575
uniprot id: A0A1L3GS16
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1842532:A7E78 RS14330
gene id: 1842532:A7E78_RS14330
uniprot id: A0A1L3GSF2
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS02095
gene id: 1842532:A7E78_RS02095
uniprot id: A0A1L3GLI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1842532:A7E78 RS00310
gene id: 1842532:A7E78_RS00310
uniprot id: A0A1L3GKK6
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS09425
gene id: 1842532:A7E78_RS09425
uniprot id: A0A1L3GQ39
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1842532:A7E78 RS11005
gene id: 1842532:A7E78_RS11005
uniprot id: A0A1L3GT33
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1842532:A7E78 RS07855
gene id: 1842532:A7E78_RS07855
uniprot id: A0A1L3GPD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1842532:A7E78 RS05750
gene id: 1842532:A7E78_RS05750
uniprot id: A0A1L3GNB9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1842532:A7E78 RS07725
gene id: 1842532:A7E78_RS07725
uniprot id: A0A1L3GP42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS05120
gene id: 1842532:A7E78_RS05120
uniprot id: A0A1L3GMY0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1842532:A7E78 RS07555
gene id: 1842532:A7E78_RS07555
uniprot id: A0A1L3GP20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1842532:A7E78 RS08150
gene id: 1842532:A7E78_RS08150
uniprot id: A0A1L3GPE0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1842532:A7E78 RS07580
gene id: 1842532:A7E78_RS07580
uniprot id: A0A1L3GP48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1842532:A7E78 RS06475
gene id: 1842532:A7E78_RS06475
uniprot id: A0A1L3GNK2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1842532:A7E78 RS02010
gene id: 1842532:A7E78_RS02010
uniprot id: A0A1L3GM30
names: Similarity
messages: Belongs to the DEAD box helicase family.

1842532:A7E78 RS11250
gene id: 1842532:A7E78_RS11250
uniprot id: A0A1L3GT63
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1842532:A7E78 RS07970
gene id: 1842532:A7E78_RS07970
uniprot id: A0A1L3GP96
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1842532:A7E78 RS05905
gene id: 1842532:A7E78_RS05905
uniprot id: A0A1L3GNC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1842532:A7E78 RS13965
gene id: 1842532:A7E78_RS13965
uniprot id: A0A1L3GT09
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1842532:A7E78 RS08670
gene id: 1842532:A7E78_RS08670
uniprot id: A0A1L3GPK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1842532:A7E78 RS05700
gene id: 1842532:A7E78_RS05700
uniprot id: A0A1L3GN54
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS08215
gene id: 1842532:A7E78_RS08215
uniprot id: A0A1L3GPG5
names: Similarity
messages: Belongs to the glutamate synthase family.

1842532:A7E78 RS00915
gene id: 1842532:A7E78_RS00915
uniprot id: A0A1L3GKT8
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

1842532:A7E78 RS03005
gene id: 1842532:A7E78_RS03005
uniprot id: A0A1L3GLV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1842532:A7E78 RS01625
gene id: 1842532:A7E78_RS01625
uniprot id: A0A1L3GLA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1842532:A7E78 RS00480
gene id: 1842532:A7E78_RS00480
uniprot id: A0A1L3GKJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1842532:A7E78 RS05510
gene id: 1842532:A7E78_RS05510
uniprot id: A0A1L3GN13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1842532:A7E78 RS11000
gene id: 1842532:A7E78_RS11000
uniprot id: A0A1L3GQT0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1842532:A7E78 RS05025
gene id: 1842532:A7E78_RS05025
uniprot id: A0A1L3GT14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1842532:A7E78 RS09705
gene id: 1842532:A7E78_RS09705
uniprot id: A0A1L3GQZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1842532:A7E78 RS10340
gene id: 1842532:A7E78_RS10340
uniprot id: A0A1L3GQQ8
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS06090
gene id: 1842532:A7E78_RS06090
uniprot id: A0A1L3GNB2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1842532:A7E78 RS08820
gene id: 1842532:A7E78_RS08820
uniprot id: A0A1L3GT36
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1842532:A7E78 RS04575
gene id: 1842532:A7E78_RS04575
uniprot id: A0A1L3GMK2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1842532:A7E78 RS01265
gene id: 1842532:A7E78_RS01265
uniprot id: A0A1L3GKX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1842532:A7E78 RS07995
gene id: 1842532:A7E78_RS07995
uniprot id: A0A1L3GPC7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1842532:A7E78 RS05990
gene id: 1842532:A7E78_RS05990
uniprot id: A0A1L3GN98
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1842532:A7E78 RS14635
gene id: 1842532:A7E78_RS14635
uniprot id: A0A1L3GSR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1842532:A7E78 RS12500
gene id: 1842532:A7E78_RS12500
uniprot id: A0A1L3GRJ1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1842532:A7E78 RS12595
gene id: 1842532:A7E78_RS12595
uniprot id: A0A1L3GT77
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1842532:A7E78 RS08375
gene id: 1842532:A7E78_RS08375
uniprot id: A0A1L3GPG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1842532:A7E78 RS04350
gene id: 1842532:A7E78_RS04350
uniprot id: A0A1L3GMG7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1842532:A7E78 RS08990
gene id: 1842532:A7E78_RS08990
uniprot id: A0A1L3GPS7
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS01460
gene id: 1842532:A7E78_RS01460
uniprot id: A0A1L3GL48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1842532:A7E78 RS06045
gene id: 1842532:A7E78_RS06045
uniprot id: A0A1L3GNB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS07500
gene id: 1842532:A7E78_RS07500
uniprot id: A0A1L3GPT2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1842532:A7E78 RS09445
gene id: 1842532:A7E78_RS09445
uniprot id: A0A1L3GQ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1842532:A7E78 RS01915
gene id: 1842532:A7E78_RS01915
uniprot id: A0A1L3GLC3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1842532:A7E78 RS00945
gene id: 1842532:A7E78_RS00945
uniprot id: A0A1L3GKX6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1842532:A7E78 RS05200
gene id: 1842532:A7E78_RS05200
uniprot id: A0A1L3GMV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1842532:A7E78 RS13355
gene id: 1842532:A7E78_RS13355
uniprot id: A0A1L3GRX5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1842532:A7E78 RS05085
gene id: 1842532:A7E78_RS05085
uniprot id: A0A1L3GMV3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1842532:A7E78 RS02310
gene id: 1842532:A7E78_RS02310
uniprot id: A0A1L3GLK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1842532:A7E78 RS06135
gene id: 1842532:A7E78_RS06135
uniprot id: A0A1L3GND3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1842532:A7E78 RS14190
gene id: 1842532:A7E78_RS14190
uniprot id: A0A1L3GSF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1842532:A7E78 RS07005
gene id: 1842532:A7E78_RS07005
uniprot id: A0A1L3GPI6
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1842532:A7E78 RS01815
gene id: 1842532:A7E78_RS01815
uniprot id: A0A1L3GL84
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1842532:A7E78 RS08400
gene id: 1842532:A7E78_RS08400
uniprot id: A0A1L3GPJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1842532:A7E78 RS07495
gene id: 1842532:A7E78_RS07495
uniprot id: A0A1L3GP11
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1842532:A7E78 RS07590
gene id: 1842532:A7E78_RS07590
uniprot id: A0A1L3GP49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1842532:A7E78 RS14560
gene id: 1842532:A7E78_RS14560
uniprot id: A0A1L3GSP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1842532:A7E78 RS07735
gene id: 1842532:A7E78_RS07735
uniprot id: A0A1L3GP54
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1842532:A7E78 RS09435
gene id: 1842532:A7E78_RS09435
uniprot id: A0A1L3GQ11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1842532:A7E78 RS01090
gene id: 1842532:A7E78_RS01090
uniprot id: A0A1L3GL05
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1842532:A7E78 RS13015
gene id: 1842532:A7E78_RS13015
uniprot id: A0A1L3GRU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

1842532:A7E78 RS01365
gene id: 1842532:A7E78_RS01365
uniprot id: A0A1L3GL03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1842532:A7E78 RS02630
gene id: 1842532:A7E78_RS02630
uniprot id: A0A1L3GLQ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS12590
gene id: 1842532:A7E78_RS12590
uniprot id: A0A1L3GRP0
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1842532:A7E78 RS08160
gene id: 1842532:A7E78_RS08160
uniprot id: A0A1L3GPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1842532:A7E78 RS06280
gene id: 1842532:A7E78_RS06280
uniprot id: A0A1L3GP62
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1842532:A7E78 RS08485
gene id: 1842532:A7E78_RS08485
uniprot id: A0A1L3GPI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1842532:A7E78 RS03110
gene id: 1842532:A7E78_RS03110
uniprot id: A0A1L3GMK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1842532:A7E78 RS07645
gene id: 1842532:A7E78_RS07645
uniprot id: A0A1L3GP86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1842532:A7E78 RS11885
gene id: 1842532:A7E78_RS11885
uniprot id: A0A1L3GR90
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1842532:A7E78 RS11365
gene id: 1842532:A7E78_RS11365
uniprot id: A0A1L3GR08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1842532:A7E78 RS00560
gene id: 1842532:A7E78_RS00560
uniprot id: A0A1L3GKL2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1842532:A7E78 RS07445
gene id: 1842532:A7E78_RS07445
uniprot id: A0A1L3GP01
names: Similarity
messages: Belongs to the TrpC family.

1842532:A7E78 RS06330
gene id: 1842532:A7E78_RS06330
uniprot id: A0A1L3GNG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1842532:A7E78 RS13675
gene id: 1842532:A7E78_RS13675
uniprot id: A0A1L3GS62
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS07460
gene id: 1842532:A7E78_RS07460
uniprot id: A0A1L3GP50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1842532:A7E78 RS10285
gene id: 1842532:A7E78_RS10285
uniprot id: A0A1L3GQF5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1842532:A7E78 RS03635
gene id: 1842532:A7E78_RS03635
uniprot id: A0A1L3GM18
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1842532:A7E78 RS03070
gene id: 1842532:A7E78_RS03070
uniprot id: A0A1L3GLU8
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1842532:A7E78 RS15470
gene id: 1842532:A7E78_RS15470
uniprot id: A0A1L3GRX8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1842532:A7E78 RS02695
gene id: 1842532:A7E78_RS02695
uniprot id: A0A1L3GLN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1842532:A7E78 RS13740
gene id: 1842532:A7E78_RS13740
uniprot id: A0A1L3GS72
names: Similarity
messages: Belongs to the cytochrome c-552 family.

1842532:A7E78 RS05955
gene id: 1842532:A7E78_RS05955
uniprot id: A0A1L3GN93
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1842532:A7E78 RS05775
gene id: 1842532:A7E78_RS05775
uniprot id: A0A1L3GNY0
names: Similarity
messages: Belongs to the UPF0047 family.

1842532:A7E78 RS01020
gene id: 1842532:A7E78_RS01020
uniprot id: A0A1L3GKW0
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1842532:A7E78 RS02705
gene id: 1842532:A7E78_RS02705
uniprot id: A0A1L3GLP5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1842532:A7E78 RS12050
gene id: 1842532:A7E78_RS12050
uniprot id: A0A1L3GRA7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1842532:A7E78 RS10920
gene id: 1842532:A7E78_RS10920
uniprot id: A0A1L3GR06
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS13745
gene id: 1842532:A7E78_RS13745
uniprot id: A0A1L3GSC7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1842532:A7E78 RS12335
gene id: 1842532:A7E78_RS12335
uniprot id: A0A1L3GRG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1842532:A7E78 RS15525
gene id: 1842532:A7E78_RS15525
uniprot id: A0A1L3GNU9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1842532:A7E78 RS10590
gene id: 1842532:A7E78_RS10590
uniprot id: A0A1L3GQL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS10495
gene id: 1842532:A7E78_RS10495
uniprot id: A0A1L3GQL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1842532:A7E78 RS12555
gene id: 1842532:A7E78_RS12555
uniprot id: A0A1L3GRN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1842532:A7E78 RS02070
gene id: 1842532:A7E78_RS02070
uniprot id: A0A1L3GM43
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1842532:A7E78 RS01085
gene id: 1842532:A7E78_RS01085
uniprot id: A0A1L3GKX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS12175
gene id: 1842532:A7E78_RS12175
uniprot id: A0A1L3GRD2
names: Similarity
messages: Belongs to the ALAD family.

1842532:A7E78 RS08475
gene id: 1842532:A7E78_RS08475
uniprot id: A0A1L3GSZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1842532:A7E78 RS03080
gene id: 1842532:A7E78_RS03080
uniprot id: A0A1L3GLV2
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1842532:A7E78 RS09380
gene id: 1842532:A7E78_RS09380
uniprot id: A0A1L3GQ66
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1842532:A7E78 RS06735
gene id: 1842532:A7E78_RS06735
uniprot id: A0A1L3GNN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1842532:A7E78 RS01695
gene id: 1842532:A7E78_RS01695
uniprot id: A0A1L3GL64
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1842532:A7E78 RS10215
gene id: 1842532:A7E78_RS10215
uniprot id: A0A1L3GQD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1842532:A7E78 RS10585
gene id: 1842532:A7E78_RS10585
uniprot id: A0A1L3GQK7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1842532:A7E78 RS01345
gene id: 1842532:A7E78_RS01345
uniprot id: A0A1L3GL29
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS03285
gene id: 1842532:A7E78_RS03285
uniprot id: A0A1L3GLW3
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1842532:A7E78 RS07840
gene id: 1842532:A7E78_RS07840
uniprot id: A0A1L3GP73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1842532:A7E78 RS01490
gene id: 1842532:A7E78_RS01490
uniprot id: A0A1L3GL28
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1842532:A7E78 RS05015
gene id: 1842532:A7E78_RS05015
uniprot id: A0A1L3GMT8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS13500
gene id: 1842532:A7E78_RS13500
uniprot id: A0A1L3GS21
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1842532:A7E78 RS10475
gene id: 1842532:A7E78_RS10475
uniprot id: A0A1L3GQM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1842532:A7E78 RS13405
gene id: 1842532:A7E78_RS13405
uniprot id: A0A1L3GS36
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1842532:A7E78 RS04705
gene id: 1842532:A7E78_RS04705
uniprot id: A0A1L3GMM8
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS01715
gene id: 1842532:A7E78_RS01715
uniprot id: A0A1L3GL65
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1842532:A7E78 RS03025
gene id: 1842532:A7E78_RS03025
uniprot id: A0A1L3GLU2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1842532:A7E78 RS03410
gene id: 1842532:A7E78_RS03410
uniprot id: A0A1L3GLY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1842532:A7E78 RS09650
gene id: 1842532:A7E78_RS09650
uniprot id: A0A1L3GQ51
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1842532:A7E78 RS01075
gene id: 1842532:A7E78_RS01075
uniprot id: A0A1L3GKX5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1842532:A7E78 RS02240
gene id: 1842532:A7E78_RS02240
uniprot id: A0A1L3GSS6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1842532:A7E78 RS01735
gene id: 1842532:A7E78_RS01735
uniprot id: A0A1L3GSY0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1842532:A7E78 RS02345
gene id: 1842532:A7E78_RS02345
uniprot id: A0A1L3GLL4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1842532:A7E78 RS06700
gene id: 1842532:A7E78_RS06700
uniprot id: A0A1L3GNM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1842532:A7E78 RS07910
gene id: 1842532:A7E78_RS07910
uniprot id: A0A1L3GPZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1842532:A7E78 RS13035
gene id: 1842532:A7E78_RS13035
uniprot id: A0A1L3GS06
names: Similarity
messages: Belongs to the UPF0751 family.

1842532:A7E78 RS04945
gene id: 1842532:A7E78_RS04945
uniprot id: A0A1L3GNH4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS11140
gene id: 1842532:A7E78_RS11140
uniprot id: A0A1L3GQW2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1842532:A7E78 RS10615
gene id: 1842532:A7E78_RS10615
uniprot id: A0A1L3GQK3
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS04885
gene id: 1842532:A7E78_RS04885
uniprot id: A0A1L3GMN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1842532:A7E78 RS12855
gene id: 1842532:A7E78_RS12855
uniprot id: A0A1L3GRQ6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1842532:A7E78 RS13980
gene id: 1842532:A7E78_RS13980
uniprot id: A0A1L3GSB1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1842532:A7E78 RS07610
gene id: 1842532:A7E78_RS07610
uniprot id: A0A1L3GPU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1842532:A7E78 RS08310
gene id: 1842532:A7E78_RS08310
uniprot id: A0A1L3GPE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1842532:A7E78 RS00200
gene id: 1842532:A7E78_RS00200
uniprot id: A0A1L3GKJ0
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1842532:A7E78 RS03365
gene id: 1842532:A7E78_RS03365
uniprot id: A0A1L3GSW2
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1842532:A7E78 RS14345
gene id: 1842532:A7E78_RS14345
uniprot id: A0A1L3GSH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1842532:A7E78 RS12165
gene id: 1842532:A7E78_RS12165
uniprot id: A0A1L3GRE2
names: Similarity
messages: Belongs to the peptidase M16 family.

1842532:A7E78 RS00185
gene id: 1842532:A7E78_RS00185
uniprot id: A0A1L3GKD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS07585
gene id: 1842532:A7E78_RS07585
uniprot id: A0A1L3GP41
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1842532:A7E78 RS11090
gene id: 1842532:A7E78_RS11090
uniprot id: A0A1L3GQY3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1842532:A7E78 RS00600
gene id: 1842532:A7E78_RS00600
uniprot id: A0A1L3GKP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1842532:A7E78 RS03930
gene id: 1842532:A7E78_RS03930
uniprot id: A0A1L3GM80
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1842532:A7E78 RS03160
gene id: 1842532:A7E78_RS03160
uniprot id: A0A1L3GLV6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1842532:A7E78 RS13995
gene id: 1842532:A7E78_RS13995
uniprot id: A0A1L3GS88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1842532:A7E78 RS03460
gene id: 1842532:A7E78_RS03460
uniprot id: A0A1L3GM50
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1842532:A7E78 RS09120
gene id: 1842532:A7E78_RS09120
uniprot id: A0A1L3GPY8
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1842532:A7E78 RS12460
gene id: 1842532:A7E78_RS12460
uniprot id: A0A1L3GSB7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1842532:A7E78 RS09030
gene id: 1842532:A7E78_RS09030
uniprot id: A0A1L3GPU0
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1842532:A7E78 RS13990
gene id: 1842532:A7E78_RS13990
uniprot id: A0A1L3GSA2
names: Similarity
messages: Belongs to the GSP E family.

1842532:A7E78 RS12190
gene id: 1842532:A7E78_RS12190
uniprot id: A0A1L3GRE0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1842532:A7E78 RS10100
gene id: 1842532:A7E78_RS10100
uniprot id: A0A1L3GQE4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1842532:A7E78 RS09010
gene id: 1842532:A7E78_RS09010
uniprot id: A0A1L3GPX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1842532:A7E78 RS03440
gene id: 1842532:A7E78_RS03440
uniprot id: A0A1L3GM47
names: Similarity
messages: Belongs to the P(II) protein family.

1842532:A7E78 RS05145
gene id: 1842532:A7E78_RS05145
uniprot id: A0A1L3GMU4
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1842532:A7E78 RS05575
gene id: 1842532:A7E78_RS05575
uniprot id: A0A1L3GN90
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1842532:A7E78 RS00805
gene id: 1842532:A7E78_RS00805
uniprot id: A0A1L3GKR7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1842532:A7E78 RS10635
gene id: 1842532:A7E78_RS10635
uniprot id: A0A1L3GQV9
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS14340
gene id: 1842532:A7E78_RS14340
uniprot id: A0A1L3GT83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1842532:A7E78 RS07110
gene id: 1842532:A7E78_RS07110
uniprot id: A0A1L3GPK8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS01925
gene id: 1842532:A7E78_RS01925
uniprot id: A0A1L3GLC5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1842532:A7E78 RS10730
gene id: 1842532:A7E78_RS10730
uniprot id: A0A1L3GRH8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1842532:A7E78 RS00715
gene id: 1842532:A7E78_RS00715
uniprot id: A0A1L3GKR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1842532:A7E78 RS10745
gene id: 1842532:A7E78_RS10745
uniprot id: A0A1L3GQY0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1842532:A7E78 RS05315
gene id: 1842532:A7E78_RS05315
uniprot id: A0A1L3GMX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1842532:A7E78 RS04965
gene id: 1842532:A7E78_RS04965
uniprot id: A0A1L3GMS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1842532:A7E78 RS09450
gene id: 1842532:A7E78_RS09450
uniprot id: A0A1L3GQ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1842532:A7E78 RS11810
gene id: 1842532:A7E78_RS11810
uniprot id: A0A1L3GRH3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1842532:A7E78 RS01690
gene id: 1842532:A7E78_RS01690
uniprot id: A0A1L3GSR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1842532:A7E78 RS11660
gene id: 1842532:A7E78_RS11660
uniprot id: A0A1L3GR71
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS13305
gene id: 1842532:A7E78_RS13305
uniprot id: A0A1L3GRW8
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

1842532:A7E78 RS01220
gene id: 1842532:A7E78_RS01220
uniprot id: A0A1L3GKY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1842532:A7E78 RS07130
gene id: 1842532:A7E78_RS07130
uniprot id: A0A1L3GNW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS12230
gene id: 1842532:A7E78_RS12230
uniprot id: A0A1L3GRE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1842532:A7E78 RS01905
gene id: 1842532:A7E78_RS01905
uniprot id: A0A1L3GLE6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1842532:A7E78 RS02845
gene id: 1842532:A7E78_RS02845
uniprot id: A0A1L3GLP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1842532:A7E78 RS00610
gene id: 1842532:A7E78_RS00610
uniprot id: A0A1L3GKT7
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1842532:A7E78 RS11965
gene id: 1842532:A7E78_RS11965
uniprot id: A0A1L3GRA1
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS13415
gene id: 1842532:A7E78_RS13415
uniprot id: A0A1L3GS09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1842532:A7E78 RS10395
gene id: 1842532:A7E78_RS10395
uniprot id: A0A1L3GQH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1842532:A7E78 RS01145
gene id: 1842532:A7E78_RS01145
uniprot id: A0A1L3GKX2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1842532:A7E78 RS08600
gene id: 1842532:A7E78_RS08600
uniprot id: A0A1L3GQC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1842532:A7E78 RS14365
gene id: 1842532:A7E78_RS14365
uniprot id: A0A1L3GSG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1842532:A7E78 RS14020
gene id: 1842532:A7E78_RS14020
uniprot id: A0A1L3GSB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1842532:A7E78 RS07635
gene id: 1842532:A7E78_RS07635
uniprot id: A0A1L3GP52
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1842532:A7E78 RS09695
gene id: 1842532:A7E78_RS09695
uniprot id: A0A1L3GQ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1842532:A7E78 RS02445
gene id: 1842532:A7E78_RS02445
uniprot id: A0A1L3GLK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1842532:A7E78 RS01845
gene id: 1842532:A7E78_RS01845
uniprot id: A0A1L3GLZ7
names: Similarity
messages: Belongs to the fabD family.

1842532:A7E78 RS07815
gene id: 1842532:A7E78_RS07815
uniprot id: A0A1L3GP84
names: Similarity
messages: Belongs to the glutamate synthase family.

1842532:A7E78 RS10315
gene id: 1842532:A7E78_RS10315
uniprot id: A0A1L3GQK2
names: Similarity
messages: Belongs to the archease family.

1842532:A7E78 RS08035
gene id: 1842532:A7E78_RS08035
uniprot id: A0A1L3GPA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1842532:A7E78 RS07615
gene id: 1842532:A7E78_RS07615
uniprot id: A0A1L3GP40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1842532:A7E78 RS08605
gene id: 1842532:A7E78_RS08605
uniprot id: A0A1L3GPK3
names: Similarity
messages: Belongs to the GSP E family.

1842532:A7E78 RS01395
gene id: 1842532:A7E78_RS01395
uniprot id: A0A1L3GL66
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1842532:A7E78 RS02645
gene id: 1842532:A7E78_RS02645
uniprot id: A0A1L3GMD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1842532:A7E78 RS04415
gene id: 1842532:A7E78_RS04415
uniprot id: A0A1L3GMI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS13550
gene id: 1842532:A7E78_RS13550
uniprot id: A0A1L3GS31
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS13835
gene id: 1842532:A7E78_RS13835
uniprot id: A0A1L3GS91
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1842532:A7E78 RS08140
gene id: 1842532:A7E78_RS08140
uniprot id: A0A1L3GPI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1842532:A7E78 RS07430
gene id: 1842532:A7E78_RS07430
uniprot id: A0A1L3GP47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1842532:A7E78 RS05505
gene id: 1842532:A7E78_RS05505
uniprot id: A0A1L3GN30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1842532:A7E78 RS01850
gene id: 1842532:A7E78_RS01850
uniprot id: A0A1L3GL99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1842532:A7E78 RS10575
gene id: 1842532:A7E78_RS10575
uniprot id: A0A1L3GQK9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1842532:A7E78 RS03390
gene id: 1842532:A7E78_RS03390
uniprot id: A0A1L3GLZ9
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS05395
gene id: 1842532:A7E78_RS05395
uniprot id: A0A1L3GMZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1842532:A7E78 RS02215
gene id: 1842532:A7E78_RS02215
uniprot id: A0A1L3GLJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1842532:A7E78 RS12645
gene id: 1842532:A7E78_RS12645
uniprot id: A0A1L3GRM3
names: Subcellular Location Annotation
messages: Cytoplasm

1842532:A7E78 RS07660
gene id: 1842532:A7E78_RS07660
uniprot id: A0A1L3GPV9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1842532:A7E78 RS13440
gene id: 1842532:A7E78_RS13440
uniprot id: A0A1L3GS81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1842532:A7E78 RS12690
gene id: 1842532:A7E78_RS12690
uniprot id: A0A1L3GRM8
names: Subcellular Location Annotation
messages: Cytoplasm

1842532:A7E78 RS07420
gene id: 1842532:A7E78_RS07420
uniprot id: A0A1L3GT17
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1842532:A7E78 RS09365
gene id: 1842532:A7E78_RS09365
uniprot id: A0A1L3GQT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1842532:A7E78 RS10735
gene id: 1842532:A7E78_RS10735
uniprot id: A0A1L3GTK0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS06710
gene id: 1842532:A7E78_RS06710
uniprot id: A0A1L3GNT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1842532:A7E78 RS00405
gene id: 1842532:A7E78_RS00405
uniprot id: A0A1L3GKK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS05445
gene id: 1842532:A7E78_RS05445
uniprot id: A0A1L3GN18
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1842532:A7E78 RS07510
gene id: 1842532:A7E78_RS07510
uniprot id: A0A1L3GP59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1842532:A7E78 RS06395
gene id: 1842532:A7E78_RS06395
uniprot id: A0A1L3GP87
names: Function
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family. Butyryl-CoA CoA-transferase subfamily.
messages: Coenzyme A-transferase that converts butyryl-CoA to butyrate.

1842532:A7E78 RS00825
gene id: 1842532:A7E78_RS00825
uniprot id: A0A1L3GKS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1842532:A7E78 RS00710
gene id: 1842532:A7E78_RS00710
uniprot id: A0A1L3GKS7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1842532:A7E78 RS06085
gene id: 1842532:A7E78_RS06085
uniprot id: A0A1L3GNH3
names: Similarity
messages: Belongs to the aspartokinase family.

1842532:A7E78 RS12675
gene id: 1842532:A7E78_RS12675
uniprot id: A0A1L3GSF4
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1842532:A7E78 RS06810
gene id: 1842532:A7E78_RS06810
uniprot id: A0A1L3GNU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1842532:A7E78 RS03100
gene id: 1842532:A7E78_RS03100
uniprot id: A0A1L3GLT9
names: Similarity
messages: Belongs to the peptidase M16 family.

1842532:A7E78 RS04570
gene id: 1842532:A7E78_RS04570
uniprot id: A0A1L3GMK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1842532:A7E78 RS07560
gene id: 1842532:A7E78_RS07560
uniprot id: A0A1L3GPU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1842532:A7E78 RS00315
gene id: 1842532:A7E78_RS00315
uniprot id: A0A1L3GKJ1
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS01470
gene id: 1842532:A7E78_RS01470
uniprot id: A0A1L3GL42
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1842532:A7E78 RS06765
gene id: 1842532:A7E78_RS06765
uniprot id: A0A1L3GNN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS08490
gene id: 1842532:A7E78_RS08490
uniprot id: A0A1L3GQA5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1842532:A7E78 RS10770
gene id: 1842532:A7E78_RS10770
uniprot id: A0A1L3GQR9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1842532:A7E78 RS06050
gene id: 1842532:A7E78_RS06050
uniprot id: A0A1L3GP25
names: Similarity
messages: Belongs to the P(II) protein family.

1842532:A7E78 RS10825
gene id: 1842532:A7E78_RS10825
uniprot id: A0A1L3GQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS06895
gene id: 1842532:A7E78_RS06895
uniprot id: A0A1L3GNS7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS04635
gene id: 1842532:A7E78_RS04635
uniprot id: A0A1L3GSV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS07680
gene id: 1842532:A7E78_RS07680
uniprot id: A0A1L3GP65
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1842532:A7E78 RS03280
gene id: 1842532:A7E78_RS03280
uniprot id: A0A1L3GSZ1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1842532:A7E78 RS04120
gene id: 1842532:A7E78_RS04120
uniprot id: A0A1L3GMC4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1842532:A7E78 RS08380
gene id: 1842532:A7E78_RS08380
uniprot id: A0A1L3GPL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1842532:A7E78 RS04100
gene id: 1842532:A7E78_RS04100
uniprot id: A0A1L3GMC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1842532:A7E78 RS12465
gene id: 1842532:A7E78_RS12465
uniprot id: A0A1L3GRJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1842532:A7E78 RS04215
gene id: 1842532:A7E78_RS04215
uniprot id: A0A1L3GMD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1842532:A7E78 RS10515
gene id: 1842532:A7E78_RS10515
uniprot id: A0A1L3GQJ9
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1842532:A7E78 RS06220
gene id: 1842532:A7E78_RS06220
uniprot id: A0A1L3GP55
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS07465
gene id: 1842532:A7E78_RS07465
uniprot id: A0A1L3GP24
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1842532:A7E78 RS12210
gene id: 1842532:A7E78_RS12210
uniprot id: A0A1L3GRE7
names: Similarity
messages: Belongs to the thioredoxin family.

1842532:A7E78 RS05300
gene id: 1842532:A7E78_RS05300
uniprot id: A0A1L3GMZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1842532:A7E78 RS12355
gene id: 1842532:A7E78_RS12355
uniprot id: A0A1L3GRH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS02470
gene id: 1842532:A7E78_RS02470
uniprot id: A0A1L3GLK0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1842532:A7E78 RS08555
gene id: 1842532:A7E78_RS08555
uniprot id: A0A1L3GPJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS02440
gene id: 1842532:A7E78_RS02440
uniprot id: A0A1L3GMA3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1842532:A7E78 RS10435
gene id: 1842532:A7E78_RS10435
uniprot id: A0A1L3GQH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1842532:A7E78 RS01950
gene id: 1842532:A7E78_RS01950
uniprot id: A0A1L3GLB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS07185
gene id: 1842532:A7E78_RS07185
uniprot id: A0A1L3GNX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1842532:A7E78 RS02020
gene id: 1842532:A7E78_RS02020
uniprot id: A0A1L3GLG6
names: Similarity
messages: Belongs to the universal stress protein A family.

1842532:A7E78 RS01740
gene id: 1842532:A7E78_RS01740
uniprot id: A0A1L3GLC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1842532:A7E78 RS02500
gene id: 1842532:A7E78_RS02500
uniprot id: A0A1L3GLJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1842532:A7E78 RS05545
gene id: 1842532:A7E78_RS05545
uniprot id: A0A1L3GN70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1842532:A7E78 RS10210
gene id: 1842532:A7E78_RS10210
uniprot id: A0A1L3GQI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1842532:A7E78 RS09000
gene id: 1842532:A7E78_RS09000
uniprot id: A0A1L3GPR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS08775
gene id: 1842532:A7E78_RS08775
uniprot id: A0A1L3GPT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1842532:A7E78 RS03045
gene id: 1842532:A7E78_RS03045
uniprot id: A0A1L3GMJ4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1842532:A7E78 RS10995
gene id: 1842532:A7E78_RS10995
uniprot id: A0A1L3GQX1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1842532:A7E78 RS03515
gene id: 1842532:A7E78_RS03515
uniprot id: A0A1L3GLZ8
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS07965
gene id: 1842532:A7E78_RS07965
uniprot id: A0A1L3GQ08
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1842532:A7E78 RS12075
gene id: 1842532:A7E78_RS12075
uniprot id: A0A1L3GRB7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS14180
gene id: 1842532:A7E78_RS14180
uniprot id: A0A1L3GSK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1842532:A7E78 RS04985
gene id: 1842532:A7E78_RS04985
uniprot id: A0A1L3GMQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1842532:A7E78 RS05580
gene id: 1842532:A7E78_RS05580
uniprot id: A0A1L3GN25
names: Similarity
messages: Belongs to the bacterial flagellin family.

1842532:A7E78 RS06240
gene id: 1842532:A7E78_RS06240
uniprot id: A0A1L3GNG6
names: Similarity
messages: Belongs to the CobH/CbiC family.

1842532:A7E78 RS04410
gene id: 1842532:A7E78_RS04410
uniprot id: A0A1L3GMH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1842532:A7E78 RS08790
gene id: 1842532:A7E78_RS08790
uniprot id: A0A1L3GPS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1842532:A7E78 RS03610
gene id: 1842532:A7E78_RS03610
uniprot id: A0A1L3GM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1842532:A7E78 RS05170
gene id: 1842532:A7E78_RS05170
uniprot id: A0A1L3GMZ2
names: Similarity
messages: Belongs to the YjdM family.

1842532:A7E78 RS00975
gene id: 1842532:A7E78_RS00975
uniprot id: A0A1L3GKV6
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS13610
gene id: 1842532:A7E78_RS13610
uniprot id: A0A1L3GS53
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1842532:A7E78 RS05660
gene id: 1842532:A7E78_RS05660
uniprot id: A0A1L3GN50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1842532:A7E78 RS00365
gene id: 1842532:A7E78_RS00365
uniprot id: A0A1L3GKK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1842532:A7E78 RS12225
gene id: 1842532:A7E78_RS12225
uniprot id: A0A1L3GRH6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS06890
gene id: 1842532:A7E78_RS06890
uniprot id: A0A1L3GNT9
names: Similarity
messages: Belongs to the UPF0178 family.

1842532:A7E78 RS07535
gene id: 1842532:A7E78_RS07535
uniprot id: A0A1L3GP43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1842532:A7E78 RS08945
gene id: 1842532:A7E78_RS08945
uniprot id: A0A1L3GPY6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS07570
gene id: 1842532:A7E78_RS07570
uniprot id: A0A1L3GP69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1842532:A7E78 RS10650
gene id: 1842532:A7E78_RS10650
uniprot id: A0A1L3GQQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1842532:A7E78 RS01610
gene id: 1842532:A7E78_RS01610
uniprot id: A0A1L3GLW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1842532:A7E78 RS04700
gene id: 1842532:A7E78_RS04700
uniprot id: A0A1L3GML8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1842532:A7E78 RS14415
gene id: 1842532:A7E78_RS14415
uniprot id: A0A1L3GSN4
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS02250
gene id: 1842532:A7E78_RS02250
uniprot id: A0A1L3GLF4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1842532:A7E78 RS14670
gene id: 1842532:A7E78_RS14670
uniprot id: A0A1L3GST8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1842532:A7E78 RS07125
gene id: 1842532:A7E78_RS07125
uniprot id: A0A1L3GNX3
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1842532:A7E78 RS07475
gene id: 1842532:A7E78_RS07475
uniprot id: A0A1L3GP19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1842532:A7E78 RS04240
gene id: 1842532:A7E78_RS04240
uniprot id: A0A1L3GME4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1842532:A7E78 RS05405
gene id: 1842532:A7E78_RS05405
uniprot id: A0A1L3GN52
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1842532:A7E78 RS14200
gene id: 1842532:A7E78_RS14200
uniprot id: A0A1L3GSC5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1842532:A7E78 RS13105
gene id: 1842532:A7E78_RS13105
uniprot id: A0A1L3GRW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1842532:A7E78 RS13135
gene id: 1842532:A7E78_RS13135
uniprot id: A0A1L3GRW9
names: Similarity
messages: Belongs to the UPF0145 family.

1842532:A7E78 RS05045
gene id: 1842532:A7E78_RS05045
uniprot id: A0A1L3GMS3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1842532:A7E78 RS09095
gene id: 1842532:A7E78_RS09095
uniprot id: A0A1L3GQN8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1842532:A7E78 RS10330
gene id: 1842532:A7E78_RS10330
uniprot id: A0A1L3GRB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1842532:A7E78 RS02400
gene id: 1842532:A7E78_RS02400
uniprot id: A0A1L3GLM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1842532:A7E78 RS02690
gene id: 1842532:A7E78_RS02690
uniprot id: A0A1L3GLS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1842532:A7E78 RS01895
gene id: 1842532:A7E78_RS01895
uniprot id: A0A1L3GM09
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS06105
gene id: 1842532:A7E78_RS06105
uniprot id: A0A1L3GNC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1842532:A7E78 RS00460
gene id: 1842532:A7E78_RS00460
uniprot id: A0A1L3GKP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1842532:A7E78 RS05745
gene id: 1842532:A7E78_RS05745
uniprot id: A0A1L3GN71
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1842532:A7E78 RS05850
gene id: 1842532:A7E78_RS05850
uniprot id: A0A1L3GNA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1842532:A7E78 RS13055
gene id: 1842532:A7E78_RS13055
uniprot id: A0A1L3GRT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1842532:A7E78 RS03355
gene id: 1842532:A7E78_RS03355
uniprot id: A0A1L3GLY7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1842532:A7E78 RS07650
gene id: 1842532:A7E78_RS07650
uniprot id: A0A1L3GP30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1842532:A7E78 RS06655
gene id: 1842532:A7E78_RS06655
uniprot id: A0A1L3GNN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1842532:A7E78 RS09740
gene id: 1842532:A7E78_RS09740
uniprot id: A0A1L3GQ99
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1842532:A7E78 RS10470
gene id: 1842532:A7E78_RS10470
uniprot id: A0A1L3GQJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1842532:A7E78 RS05150
gene id: 1842532:A7E78_RS05150
uniprot id: A0A1L3GMU9
names: Similarity
messages: Belongs to the UPF0237 family.

1842532:A7E78 RS01640
gene id: 1842532:A7E78_RS01640
uniprot id: A0A1L3GL76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1842532:A7E78 RS14275
gene id: 1842532:A7E78_RS14275
uniprot id: A0A1L3GSG9
names: Similarity
messages: Belongs to the acylphosphatase family.

1842532:A7E78 RS11040
gene id: 1842532:A7E78_RS11040
uniprot id: A0A1L3GQX3
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1842532:A7E78 RS06235
gene id: 1842532:A7E78_RS06235
uniprot id: A0A1L3GNH6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1842532:A7E78 RS13690
gene id: 1842532:A7E78_RS13690
uniprot id: A0A1L3GS52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1842532:A7E78 RS00950
gene id: 1842532:A7E78_RS00950
uniprot id: A0A1L3GKW9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1842532:A7E78 RS03820
gene id: 1842532:A7E78_RS03820
uniprot id: A0A1L3GM73
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1842532:A7E78 RS13130
gene id: 1842532:A7E78_RS13130
uniprot id: A0A1L3GSL6
names: Similarity
messages: Belongs to the UPF0145 family.

1842532:A7E78 RS08530
gene id: 1842532:A7E78_RS08530
uniprot id: A0A1L3GPL4
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS07640
gene id: 1842532:A7E78_RS07640
uniprot id: A0A1L3GP56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1842532:A7E78 RS14260
gene id: 1842532:A7E78_RS14260
uniprot id: A0A1L3GSD5
names: Similarity
messages: Belongs to the UPF0102 family.

1842532:A7E78 RS10360
gene id: 1842532:A7E78_RS10360
uniprot id: A0A1L3GQJ7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1842532:A7E78 RS13410
gene id: 1842532:A7E78_RS13410
uniprot id: A0A1L3GRY5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1842532:A7E78 RS00230
gene id: 1842532:A7E78_RS00230
uniprot id: A0A1L3GKL7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1842532:A7E78 RS03150
gene id: 1842532:A7E78_RS03150
uniprot id: A0A1L3GM02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1842532:A7E78 RS08360
gene id: 1842532:A7E78_RS08360
uniprot id: A0A1L3GPG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS03010
gene id: 1842532:A7E78_RS03010
uniprot id: A0A1L3GLW8
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1842532:A7E78 RS05460
gene id: 1842532:A7E78_RS05460
uniprot id: A0A1L3GN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1842532:A7E78 RS08675
gene id: 1842532:A7E78_RS08675
uniprot id: A0A1L3GPM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1842532:A7E78 RS01785
gene id: 1842532:A7E78_RS01785
uniprot id: A0A1L3GL89
names: Subcellular Location Annotation
messages: Cytoplasm

1842532:A7E78 RS02655
gene id: 1842532:A7E78_RS02655
uniprot id: A0A1L3GLR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1842532:A7E78 RS04165
gene id: 1842532:A7E78_RS04165
uniprot id: A0A1L3GMD5
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS13400
gene id: 1842532:A7E78_RS13400
uniprot id: A0A1L3GRZ2
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1842532:A7E78 RS09210
gene id: 1842532:A7E78_RS09210
uniprot id: A0A1L3GQ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1842532:A7E78 RS05965
gene id: 1842532:A7E78_RS05965
uniprot id: A0A1L3GNC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS08745
gene id: 1842532:A7E78_RS08745
uniprot id: A0A1L3GPP6
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS10645
gene id: 1842532:A7E78_RS10645
uniprot id: A0A1L3GQM1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1842532:A7E78 RS07360
gene id: 1842532:A7E78_RS07360
uniprot id: A0A1L3GP07
names: Similarity
messages: Belongs to the peptidase C40 family.

1842532:A7E78 RS11840
gene id: 1842532:A7E78_RS11840
uniprot id: A0A1L3GR74
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS01450
gene id: 1842532:A7E78_RS01450
uniprot id: A0A1L3GL67
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1842532:A7E78 RS03015
gene id: 1842532:A7E78_RS03015
uniprot id: A0A1L3GLT8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1842532:A7E78 RS08965
gene id: 1842532:A7E78_RS08965
uniprot id: A0A1L3GPT4
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS13560
gene id: 1842532:A7E78_RS13560
uniprot id: A0A1L3GS35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1842532:A7E78 RS13030
gene id: 1842532:A7E78_RS13030
uniprot id: A0A1L3GRU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1842532:A7E78 RS13215
gene id: 1842532:A7E78_RS13215
uniprot id: A0A1L3GRY1
names: Similarity
messages: Belongs to the SfsA family.

1842532:A7E78 RS11675
gene id: 1842532:A7E78_RS11675
uniprot id: A0A1L3GR79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1842532:A7E78 RS14265
gene id: 1842532:A7E78_RS14265
uniprot id: A0A1L3GSJ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS01655
gene id: 1842532:A7E78_RS01655
uniprot id: A0A1L3GL50
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1842532:A7E78 RS14135
gene id: 1842532:A7E78_RS14135
uniprot id: A0A1L3GSD9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1842532:A7E78 RS02480
gene id: 1842532:A7E78_RS02480
uniprot id: A0A1L3GLL6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1842532:A7E78 RS07310
gene id: 1842532:A7E78_RS07310
uniprot id: A0A1L3GNW2
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1842532:A7E78 RS06740
gene id: 1842532:A7E78_RS06740
uniprot id: A0A1L3GNT0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1842532:A7E78 RS04075
gene id: 1842532:A7E78_RS04075
uniprot id: A0A1L3GMF8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1842532:A7E78 RS06805
gene id: 1842532:A7E78_RS06805
uniprot id: A0A1L3GNP7
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

1842532:A7E78 RS05055
gene id: 1842532:A7E78_RS05055
uniprot id: A0A1L3GNJ5
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS00870
gene id: 1842532:A7E78_RS00870
uniprot id: A0A1L3GKR0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1842532:A7E78 RS00905
gene id: 1842532:A7E78_RS00905
uniprot id: A0A1L3GKU6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1842532:A7E78 RS12800
gene id: 1842532:A7E78_RS12800
uniprot id: A0A1L3GRP6
names: Subcellular Location Annotation
messages: Cytoplasm

1842532:A7E78 RS02465
gene id: 1842532:A7E78_RS02465
uniprot id: A0A1L3GLK9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1842532:A7E78 RS09050
gene id: 1842532:A7E78_RS09050
uniprot id: A0A1L3GQ07
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS10450
gene id: 1842532:A7E78_RS10450
uniprot id: A0A1L3GQJ0
names: Similarity
messages: Belongs to the ParB family.

1842532:A7E78 RS10230
gene id: 1842532:A7E78_RS10230
uniprot id: A0A1L3GQE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS14290
gene id: 1842532:A7E78_RS14290
uniprot id: A0A1L3GSG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1842532:A7E78 RS13140
gene id: 1842532:A7E78_RS13140
uniprot id: A0A1L3GS30
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS09505
gene id: 1842532:A7E78_RS09505
uniprot id: A0A1L3GQ03
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1842532:A7E78 RS10740
gene id: 1842532:A7E78_RS10740
uniprot id: A0A1L3GQN2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1842532:A7E78 RS10140
gene id: 1842532:A7E78_RS10140
uniprot id: A0A1L3GQE1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS03465
gene id: 1842532:A7E78_RS03465
uniprot id: A0A1L3GLY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1842532:A7E78 RS06880
gene id: 1842532:A7E78_RS06880
uniprot id: A0A1L3GNQ6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1842532:A7E78 RS01670
gene id: 1842532:A7E78_RS01670
uniprot id: A0A1L3GL69
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1842532:A7E78 RS09075
gene id: 1842532:A7E78_RS09075
uniprot id: A0A1L3GPV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS01150
gene id: 1842532:A7E78_RS01150
uniprot id: A0A1L3GKW7
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1842532:A7E78 RS08850
gene id: 1842532:A7E78_RS08850
uniprot id: A0A1L3GPS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1842532:A7E78 RS01835
gene id: 1842532:A7E78_RS01835
uniprot id: A0A1L3GSQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1842532:A7E78 RS12850
gene id: 1842532:A7E78_RS12850
uniprot id: A0A1L3GRR7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1842532:A7E78 RS01765
gene id: 1842532:A7E78_RS01765
uniprot id: A0A1L3GLB1
names: Subcellular Location Annotation
messages: Nucleus

1842532:A7E78 RS11495
gene id: 1842532:A7E78_RS11495
uniprot id: A0A1L3GR11
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1842532:A7E78 RS06670
gene id: 1842532:A7E78_RS06670
uniprot id: A0A1L3GNN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1842532:A7E78 RS01165
gene id: 1842532:A7E78_RS01165
uniprot id: A0A1L3GKY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS01390
gene id: 1842532:A7E78_RS01390
uniprot id: A0A1L3GL55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1842532:A7E78 RS13665
gene id: 1842532:A7E78_RS13665
uniprot id: A0A1L3GSB6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1842532:A7E78 RS13335
gene id: 1842532:A7E78_RS13335
uniprot id: A0A1L3GRZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1842532:A7E78 RS13235
gene id: 1842532:A7E78_RS13235
uniprot id: A0A1L3GS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1842532:A7E78 RS04325
gene id: 1842532:A7E78_RS04325
uniprot id: A0A1L3GMF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1842532:A7E78 RS04305
gene id: 1842532:A7E78_RS04305
uniprot id: A0A1L3GMF4
names: Similarity
messages: Belongs to the peptidase S49 family.

1842532:A7E78 RS02735
gene id: 1842532:A7E78_RS02735
uniprot id: A0A1L3GLM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane

1842532:A7E78 RS02200
gene id: 1842532:A7E78_RS02200
uniprot id: A0A1L3GLE5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1842532:A7E78 RS04900
gene id: 1842532:A7E78_RS04900
uniprot id: A0A1L3GMQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1842532:A7E78 RS09465
gene id: 1842532:A7E78_RS09465
uniprot id: A0A1L3GQ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1842532:A7E78 RS06080
gene id: 1842532:A7E78_RS06080
uniprot id: A0A1L3GND0
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1842532:A7E78 RS11225
gene id: 1842532:A7E78_RS11225
uniprot id: A0A1L3GQW4
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS07485
gene id: 1842532:A7E78_RS07485
uniprot id: A0A1L3GP58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1842532:A7E78 RS01920
gene id: 1842532:A7E78_RS01920
uniprot id: A0A1L3GLA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS10295
gene id: 1842532:A7E78_RS10295
uniprot id: A0A1L3GQF2
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS08130
gene id: 1842532:A7E78_RS08130
uniprot id: A0A1L3GQ38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1842532:A7E78 RS13370
gene id: 1842532:A7E78_RS13370
uniprot id: A0A1L3GSQ5
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1842532:A7E78 RS06410
gene id: 1842532:A7E78_RS06410
uniprot id: A0A1L3GNK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1842532:A7E78 RS07425
gene id: 1842532:A7E78_RS07425
uniprot id: A0A1L3GP17
names: Similarity
messages: Belongs to the DEAD box helicase family.

1842532:A7E78 RS01525
gene id: 1842532:A7E78_RS01525
uniprot id: A0A1L3GL58
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1842532:A7E78 RS10815
gene id: 1842532:A7E78_RS10815
uniprot id: A0A1L3GQP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

1842532:A7E78 RS05485
gene id: 1842532:A7E78_RS05485
uniprot id: A0A1L3GNS4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1842532:A7E78 RS03030
gene id: 1842532:A7E78_RS03030
uniprot id: A0A1L3GLX2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS12660
gene id: 1842532:A7E78_RS12660
uniprot id: A0A1L3GRR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1842532:A7E78 RS12725
gene id: 1842532:A7E78_RS12725
uniprot id: A0A1L3GSG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1842532:A7E78 RS07415
gene id: 1842532:A7E78_RS07415
uniprot id: A0A1L3GP03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1842532:A7E78 RS09985
gene id: 1842532:A7E78_RS09985
uniprot id: A0A1L3GQA9
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS08110
gene id: 1842532:A7E78_RS08110
uniprot id: A0A1L3GPE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1842532:A7E78 RS07080
gene id: 1842532:A7E78_RS07080
uniprot id: A0A1L3GNW0
names: Similarity
messages: Belongs to the FBPase class 2 family.

1842532:A7E78 RS07655
gene id: 1842532:A7E78_RS07655
uniprot id: A0A1L3GP37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1842532:A7E78 RS01385
gene id: 1842532:A7E78_RS01385
uniprot id: A0A1L3GL17
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS08355
gene id: 1842532:A7E78_RS08355
uniprot id: A0A1L3GPG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1842532:A7E78 RS06225
gene id: 1842532:A7E78_RS06225
uniprot id: A0A1L3GNE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1842532:A7E78 RS12195
gene id: 1842532:A7E78_RS12195
uniprot id: A0A1L3GT82
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS01225
gene id: 1842532:A7E78_RS01225
uniprot id: A0A1L3GL21
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS10490
gene id: 1842532:A7E78_RS10490
uniprot id: A0A1L3GQI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1842532:A7E78 RS08345
gene id: 1842532:A7E78_RS08345
uniprot id: A0A1L3GPK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1842532:A7E78 RS08200
gene id: 1842532:A7E78_RS08200
uniprot id: A0A1L3GPC9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1842532:A7E78 RS02225
gene id: 1842532:A7E78_RS02225
uniprot id: A0A1L3GLG5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1842532:A7E78 RS14675
gene id: 1842532:A7E78_RS14675
uniprot id: A0A1L3GSN7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1842532:A7E78 RS06815
gene id: 1842532:A7E78_RS06815
uniprot id: A0A1L3GNS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS05945
gene id: 1842532:A7E78_RS05945
uniprot id: A0A1L3GP08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1842532:A7E78 RS08470
gene id: 1842532:A7E78_RS08470
uniprot id: A0A1L3GPL9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1842532:A7E78 RS09970
gene id: 1842532:A7E78_RS09970
uniprot id: A0A1L3GT37
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1842532:A7E78 RS07100
gene id: 1842532:A7E78_RS07100
uniprot id: A0A1L3GNS2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1842532:A7E78 RS13895
gene id: 1842532:A7E78_RS13895
uniprot id: A0A1L3GT76
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1842532:A7E78 RS13160
gene id: 1842532:A7E78_RS13160
uniprot id: A0A1L3GRW7
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS14450
gene id: 1842532:A7E78_RS14450
uniprot id: A0A1L3GSH1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1842532:A7E78 RS07625
gene id: 1842532:A7E78_RS07625
uniprot id: A0A1L3GP53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1842532:A7E78 RS04650
gene id: 1842532:A7E78_RS04650
uniprot id: A0A1L3GMK9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1842532:A7E78 RS09165
gene id: 1842532:A7E78_RS09165
uniprot id: A0A1L3GPU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1842532:A7E78 RS12470
gene id: 1842532:A7E78_RS12470
uniprot id: A0A1L3GRS5
names: Similarity
messages: Belongs to the glutamate synthase family.

1842532:A7E78 RS00965
gene id: 1842532:A7E78_RS00965
uniprot id: A0A1L3GKS6
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS14460
gene id: 1842532:A7E78_RS14460
uniprot id: A0A1L3GTA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS11020
gene id: 1842532:A7E78_RS11020
uniprot id: A0A1L3GQT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1842532:A7E78 RS02760
gene id: 1842532:A7E78_RS02760
uniprot id: A0A1L3GLP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1842532:A7E78 RS09270
gene id: 1842532:A7E78_RS09270
uniprot id: A0A1L3GPW3
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1842532:A7E78 RS13605
gene id: 1842532:A7E78_RS13605
uniprot id: A0A1L3GSA4
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS06265
gene id: 1842532:A7E78_RS06265
uniprot id: A0A1L3GNK3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1842532:A7E78 RS00645
gene id: 1842532:A7E78_RS00645
uniprot id: A0A1L3GKS1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS10655
gene id: 1842532:A7E78_RS10655
uniprot id: A0A1L3GQQ0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1842532:A7E78 RS11720
gene id: 1842532:A7E78_RS11720
uniprot id: A0A1L3GR96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1842532:A7E78 RS14685
gene id: 1842532:A7E78_RS14685
uniprot id: A0A1L3GSM1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1842532:A7E78 RS00695
gene id: 1842532:A7E78_RS00695
uniprot id: A0A1L3GLH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1842532:A7E78 RS06540
gene id: 1842532:A7E78_RS06540
uniprot id: A0A1L3GNQ5
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS14545
gene id: 1842532:A7E78_RS14545
uniprot id: A0A1L3GSL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1842532:A7E78 RS03435
gene id: 1842532:A7E78_RS03435
uniprot id: A0A1L3GM42
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1842532:A7E78 RS04375
gene id: 1842532:A7E78_RS04375
uniprot id: A0A1L3GMF2
names: Similarity
messages: Belongs to the RecJ family.

1842532:A7E78 RS07920
gene id: 1842532:A7E78_RS07920
uniprot id: A0A1L3GPE4
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1842532:A7E78 RS13505
gene id: 1842532:A7E78_RS13505
uniprot id: A0A1L3GS24
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS13540
gene id: 1842532:A7E78_RS13540
uniprot id: A0A1L3GS98
names: Similarity
messages: Belongs to the CvfB family.

1842532:A7E78 RS05105
gene id: 1842532:A7E78_RS05105
uniprot id: A0A1L3GNK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1842532:A7E78 RS13960
gene id: 1842532:A7E78_RS13960
uniprot id: A0A1L3GSB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1842532:A7E78 RS04665
gene id: 1842532:A7E78_RS04665
uniprot id: A0A1L3GMK3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1842532:A7E78 RS07270
gene id: 1842532:A7E78_RS07270
uniprot id: A0A1L3GPP3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS08920
gene id: 1842532:A7E78_RS08920
uniprot id: A0A1L3GPS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1842532:A7E78 RS08900
gene id: 1842532:A7E78_RS08900
uniprot id: A0A1L3GPV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS03535
gene id: 1842532:A7E78_RS03535
uniprot id: A0A1L3GM16
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

1842532:A7E78 RS01860
gene id: 1842532:A7E78_RS01860
uniprot id: A0A1L3GLE4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1842532:A7E78 RS12185
gene id: 1842532:A7E78_RS12185
uniprot id: A0A1L3GS70
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1842532:A7E78 RS08785
gene id: 1842532:A7E78_RS08785
uniprot id: A0A1L3GPP1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1842532:A7E78 RS04895
gene id: 1842532:A7E78_RS04895
uniprot id: A0A1L3GNG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1842532:A7E78 RS05190
gene id: 1842532:A7E78_RS05190
uniprot id: A0A1L3GN14
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1842532:A7E78 RS05680
gene id: 1842532:A7E78_RS05680
uniprot id: A0A1L3GN43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1842532:A7E78 RS06015
gene id: 1842532:A7E78_RS06015
uniprot id: A0A1L3GND7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS08175
gene id: 1842532:A7E78_RS08175
uniprot id: A0A1L3GPD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1842532:A7E78 RS08260
gene id: 1842532:A7E78_RS08260
uniprot id: A0A1L3GPG0
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1842532:A7E78 RS07600
gene id: 1842532:A7E78_RS07600
uniprot id: A0A1L3GP21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1842532:A7E78 RS14570
gene id: 1842532:A7E78_RS14570
uniprot id: A0A1L3GSJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1842532:A7E78 RS12035
gene id: 1842532:A7E78_RS12035
uniprot id: A0A1L3GRE9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS09880
gene id: 1842532:A7E78_RS09880
uniprot id: A0A1L3GQC3
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS02615
gene id: 1842532:A7E78_RS02615
uniprot id: A0A1L3GLM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1842532:A7E78 RS12805
gene id: 1842532:A7E78_RS12805
uniprot id: A0A1L3GRQ1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1842532:A7E78 RS00455
gene id: 1842532:A7E78_RS00455
uniprot id: A0A1L3GKL4
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS03475
gene id: 1842532:A7E78_RS03475
uniprot id: A0A1L3GMT2
names: Similarity
messages: Belongs to the peptidase A24 family.

1842532:A7E78 RS13460
gene id: 1842532:A7E78_RS13460
uniprot id: A0A1L3GS04
names: Similarity
messages: Belongs to the SCO1/2 family.

1842532:A7E78 RS11590
gene id: 1842532:A7E78_RS11590
uniprot id: A0A1L3GR31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1842532:A7E78 RS07085
gene id: 1842532:A7E78_RS07085
uniprot id: A0A1L3GNU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1842532:A7E78 RS07740
gene id: 1842532:A7E78_RS07740
uniprot id: A0A1L3GPW7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1842532:A7E78 RS12445
gene id: 1842532:A7E78_RS12445
uniprot id: A0A1L3GRL8
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1842532:A7E78 RS11025
gene id: 1842532:A7E78_RS11025
uniprot id: A0A1L3GR24
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1842532:A7E78 RS06825
gene id: 1842532:A7E78_RS06825
uniprot id: A0A1L3GNQ1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1842532:A7E78 RS00700
gene id: 1842532:A7E78_RS00700
uniprot id: A0A1L3GKQ4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1842532:A7E78 RS13210
gene id: 1842532:A7E78_RS13210
uniprot id: A0A1L3GS38
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1842532:A7E78 RS10185
gene id: 1842532:A7E78_RS10185
uniprot id: A0A1L3GQD6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1842532:A7E78 RS03330
gene id: 1842532:A7E78_RS03330
uniprot id: A0A1L3GLY1
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS00745
gene id: 1842532:A7E78_RS00745
uniprot id: A0A1L3GLH9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1842532:A7E78 RS12340
gene id: 1842532:A7E78_RS12340
uniprot id: A0A1L3GRI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1842532:A7E78 RS10915
gene id: 1842532:A7E78_RS10915
uniprot id: A0A1L3GQR7
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS09940
gene id: 1842532:A7E78_RS09940
uniprot id: A0A1L3GQD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1842532:A7E78 RS13945
gene id: 1842532:A7E78_RS13945
uniprot id: A0A1L3GS80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1842532:A7E78 RS14440
gene id: 1842532:A7E78_RS14440
uniprot id: A0A1L3GSG5
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1842532:A7E78 RS09375
gene id: 1842532:A7E78_RS09375
uniprot id: A0A1L3GPZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1842532:A7E78 RS09185
gene id: 1842532:A7E78_RS09185
uniprot id: A0A1L3GPZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1842532:A7E78 RS04920
gene id: 1842532:A7E78_RS04920
uniprot id: A0A1L3GMQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1842532:A7E78 RS14405
gene id: 1842532:A7E78_RS14405
uniprot id: A0A1L3GSI6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1842532:A7E78 RS00595
gene id: 1842532:A7E78_RS00595
uniprot id: A0A1L3GKL6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1842532:A7E78 RS03000
gene id: 1842532:A7E78_RS03000
uniprot id: A0A1L3GLT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1842532:A7E78 RS14660
gene id: 1842532:A7E78_RS14660
uniprot id: A0A1L3GSM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1842532:A7E78 RS00865
gene id: 1842532:A7E78_RS00865
uniprot id: A0A1L3GKS5
names: Similarity
messages: Belongs to the NifX/NifY family.

1842532:A7E78 RS09420
gene id: 1842532:A7E78_RS09420
uniprot id: A0A1L3GQ19
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1842532:A7E78 RS12815
gene id: 1842532:A7E78_RS12815
uniprot id: A0A1L3GRR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1842532:A7E78 RS05475
gene id: 1842532:A7E78_RS05475
uniprot id: A0A1L3GN08
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1842532:A7E78 RS03620
gene id: 1842532:A7E78_RS03620
uniprot id: A0A1L3GM33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1842532:A7E78 RS02155
gene id: 1842532:A7E78_RS02155
uniprot id: A0A1L3GLI6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1842532:A7E78 RS01635
gene id: 1842532:A7E78_RS01635
uniprot id: A0A1L3GL54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1842532:A7E78 RS07960
gene id: 1842532:A7E78_RS07960
uniprot id: A0A1L3GSY1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1842532:A7E78 RS03925
gene id: 1842532:A7E78_RS03925
uniprot id: A0A1L3GM69
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1842532:A7E78 RS11470
gene id: 1842532:A7E78_RS11470
uniprot id: A0A1L3GR10
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1842532:A7E78 RS11390
gene id: 1842532:A7E78_RS11390
uniprot id: A0A1L3GR28
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1842532:A7E78 RS03780
gene id: 1842532:A7E78_RS03780
uniprot id: A0A1L3GMA6
names: Similarity
messages: Belongs to the AOR/FOR family.

1842532:A7E78 RS04845
gene id: 1842532:A7E78_RS04845
uniprot id: A0A1L3GNF7
names: Similarity
messages: Belongs to the RecJ family.

1842532:A7E78 RS07410
gene id: 1842532:A7E78_RS07410
uniprot id: A0A1L3GP16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1842532:A7E78 RS07575
gene id: 1842532:A7E78_RS07575
uniprot id: A0A1L3GP44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1842532:A7E78 RS10620
gene id: 1842532:A7E78_RS10620
uniprot id: A0A1L3GQN6
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS02770
gene id: 1842532:A7E78_RS02770
uniprot id: A0A1L3GLT1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1842532:A7E78 RS06720
gene id: 1842532:A7E78_RS06720
uniprot id: A0A1L3GNP0
names: Similarity
messages: Belongs to the ros/MucR family.

1842532:A7E78 RS14115
gene id: 1842532:A7E78_RS14115
uniprot id: A0A1L3GT40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1842532:A7E78 RS07900
gene id: 1842532:A7E78_RS07900
uniprot id: A0A1L3GP67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1842532:A7E78 RS06115
gene id: 1842532:A7E78_RS06115
uniprot id: A0A1L3GNF5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1842532:A7E78 RS10405
gene id: 1842532:A7E78_RS10405
uniprot id: A0A1L3GQL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1842532:A7E78 RS14075
gene id: 1842532:A7E78_RS14075
uniprot id: A0A1L3GSI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1842532:A7E78 RS01370
gene id: 1842532:A7E78_RS01370
uniprot id: A0A1L3GL00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1842532:A7E78 RS00705
gene id: 1842532:A7E78_RS00705
uniprot id: A0A1L3GKT0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1842532:A7E78 RS07440
gene id: 1842532:A7E78_RS07440
uniprot id: A0A1L3GNY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1842532:A7E78 RS05375
gene id: 1842532:A7E78_RS05375
uniprot id: A0A1L3GMZ5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1842532:A7E78 RS04480
gene id: 1842532:A7E78_RS04480
uniprot id: A0A1L3GMH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS01900
gene id: 1842532:A7E78_RS01900
uniprot id: A0A1L3GLA9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1842532:A7E78 RS12580
gene id: 1842532:A7E78_RS12580
uniprot id: A0A1L3GRK7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1842532:A7E78 RS13295
gene id: 1842532:A7E78_RS13295
uniprot id: A0A1L3GRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1842532:A7E78 RS09290
gene id: 1842532:A7E78_RS09290
uniprot id: A0A1L3GQ12
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1842532:A7E78 RS01885
gene id: 1842532:A7E78_RS01885
uniprot id: A0A1L3GL90
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1842532:A7E78 RS10310
gene id: 1842532:A7E78_RS10310
uniprot id: A0A1L3GQI7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1842532:A7E78 RS13955
gene id: 1842532:A7E78_RS13955
uniprot id: A0A1L3GS75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1842532:A7E78 RS09135
gene id: 1842532:A7E78_RS09135
uniprot id: A0A1L3GPU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1842532:A7E78 RS14315
gene id: 1842532:A7E78_RS14315
uniprot id: A0A1L3GSF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1842532:A7E78 RS00850
gene id: 1842532:A7E78_RS00850
uniprot id: A0A1L3GSP1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-99 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1842532:A7E78 RS02625
gene id: 1842532:A7E78_RS02625
uniprot id: A0A1L3GLN5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1842532:A7E78 RS11845
gene id: 1842532:A7E78_RS11845
uniprot id: A0A1L3GRB2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS08665
gene id: 1842532:A7E78_RS08665
uniprot id: A0A1L3GPR8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1842532:A7E78 RS08540
gene id: 1842532:A7E78_RS08540
uniprot id: A0A1L3GPJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1842532:A7E78 RS04925
gene id: 1842532:A7E78_RS04925
uniprot id: A0A1L3GMS1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1842532:A7E78 RS02710
gene id: 1842532:A7E78_RS02710
uniprot id: A0A1L3GSU1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1842532:A7E78 RS14025
gene id: 1842532:A7E78_RS14025
uniprot id: A0A1L3GSH8
names: Similarity
messages: Belongs to the LarC family.

1842532:A7E78 RS00265
gene id: 1842532:A7E78_RS00265
uniprot id: A0A1L3GKI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1842532:A7E78 RS08765
gene id: 1842532:A7E78_RS08765
uniprot id: A0A1L3GQF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1842532:A7E78 RS13445
gene id: 1842532:A7E78_RS13445
uniprot id: A0A1L3GS23
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS14280
gene id: 1842532:A7E78_RS14280
uniprot id: A0A1L3GT73
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1842532:A7E78 RS00750
gene id: 1842532:A7E78_RS00750
uniprot id: A0A1L3GKR5
names: Similarity
messages: Belongs to the citrate synthase family.

1842532:A7E78 RS06840
gene id: 1842532:A7E78_RS06840
uniprot id: A0A1L3GNN8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1842532:A7E78 RS12685
gene id: 1842532:A7E78_RS12685
uniprot id: A0A1L3GRV6
names: Similarity
messages: Belongs to the YggT family.

1842532:A7E78 RS01865
gene id: 1842532:A7E78_RS01865
uniprot id: A0A1L3GLB3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1842532:A7E78 RS01330
gene id: 1842532:A7E78_RS01330
uniprot id: A0A1L3GL07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1842532:A7E78 RS00355
gene id: 1842532:A7E78_RS00355
uniprot id: A0A1L3GKM1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1842532:A7E78 RS08335
gene id: 1842532:A7E78_RS08335
uniprot id: A0A1L3GPJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1842532:A7E78 RS05550
gene id: 1842532:A7E78_RS05550
uniprot id: A0A1L3GN59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1842532:A7E78 RS05290
gene id: 1842532:A7E78_RS05290
uniprot id: A0A1L3GMY8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1842532:A7E78 RS04430
gene id: 1842532:A7E78_RS04430
uniprot id: A0A1L3GMH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1842532:A7E78 RS10860
gene id: 1842532:A7E78_RS10860
uniprot id: A0A1L3GQQ6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1842532:A7E78 RS15275
gene id: 1842532:A7E78_RS15275
uniprot id: A0A1L3GLG4
names: Similarity
messages: Belongs to the MipA/OmpV family.

1842532:A7E78 RS01360
gene id: 1842532:A7E78_RS01360
uniprot id: A0A1L3GL47
names: Similarity
messages: Belongs to the Skp family.

1842532:A7E78 RS04580
gene id: 1842532:A7E78_RS04580
uniprot id: A0A1L3GMK8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1842532:A7E78 RS00045
gene id: 1842532:A7E78_RS00045
uniprot id: A0A1L3GL60
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1842532:A7E78 RS07095
gene id: 1842532:A7E78_RS07095
uniprot id: A0A1L3GNZ4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1842532:A7E78 RS10625
gene id: 1842532:A7E78_RS10625
uniprot id: A0A1L3GRG3
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS14455
gene id: 1842532:A7E78_RS14455
uniprot id: A0A1L3GSJ9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1842532:A7E78 RS10890
gene id: 1842532:A7E78_RS10890
uniprot id: A0A1L3GQV2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1842532:A7E78 RS08870
gene id: 1842532:A7E78_RS08870
uniprot id: A0A1L3GQI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1842532:A7E78 RS14375
gene id: 1842532:A7E78_RS14375
uniprot id: A0A1L3GSL1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1842532:A7E78 RS02765
gene id: 1842532:A7E78_RS02765
uniprot id: A0A1L3GLS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1842532:A7E78 RS09590
gene id: 1842532:A7E78_RS09590
uniprot id: A0A1L3GQ22
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1842532:A7E78 RS14120
gene id: 1842532:A7E78_RS14120
uniprot id: A0A1L3GSD4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1842532:A7E78 RS07915
gene id: 1842532:A7E78_RS07915
uniprot id: A0A1L3GP91
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1842532:A7E78 RS11410
gene id: 1842532:A7E78_RS11410
uniprot id: A0A1L3GR98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1842532:A7E78 RS00860
gene id: 1842532:A7E78_RS00860
uniprot id: A0A1L3GKX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1842532:A7E78 RS09045
gene id: 1842532:A7E78_RS09045
uniprot id: A0A1L3GPT6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1842532:A7E78 RS04300
gene id: 1842532:A7E78_RS04300
uniprot id: A0A1L3GMF6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1842532:A7E78 RS04145
gene id: 1842532:A7E78_RS04145
uniprot id: A0A1L3GN45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1842532:A7E78 RS14175
gene id: 1842532:A7E78_RS14175
uniprot id: A0A1L3GSE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1842532:A7E78 RS11220
gene id: 1842532:A7E78_RS11220
uniprot id: A0A1L3GR12
names: Similarity
messages: Belongs to the MYG1 family.

1842532:A7E78 RS00690
gene id: 1842532:A7E78_RS00690
uniprot id: A0A1L3GKN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1842532:A7E78 RS03545
gene id: 1842532:A7E78_RS03545
uniprot id: A0A1L3GM67
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS03320
gene id: 1842532:A7E78_RS03320
uniprot id: A0A1L3GM34
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS10400
gene id: 1842532:A7E78_RS10400
uniprot id: A0A1L3GQI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1842532:A7E78 RS04310
gene id: 1842532:A7E78_RS04310
uniprot id: A0A1L3GMF9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1842532:A7E78 RS00655
gene id: 1842532:A7E78_RS00655
uniprot id: A0A1L3GKQ2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1842532:A7E78 RS00100
gene id: 1842532:A7E78_RS00100
uniprot id: A0A1L3GSP2
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1842532:A7E78 RS12415
gene id: 1842532:A7E78_RS12415
uniprot id: A0A1L3GRH7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1842532:A7E78 RS13620
gene id: 1842532:A7E78_RS13620
uniprot id: A0A1L3GS45
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1842532:A7E78 RS02120
gene id: 1842532:A7E78_RS02120
uniprot id: A0A1L3GLH4
names: Similarity
messages: Belongs to the MEMO1 family.

1842532:A7E78 RS03890
gene id: 1842532:A7E78_RS03890
uniprot id: A0A1L3GMB8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1842532:A7E78 RS07620
gene id: 1842532:A7E78_RS07620
uniprot id: A0A1L3GP85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1842532:A7E78 RS02730
gene id: 1842532:A7E78_RS02730
uniprot id: A0A1L3GLS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1842532:A7E78 RS04115
gene id: 1842532:A7E78_RS04115
uniprot id: A0A1L3GMC5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1842532:A7E78 RS10485
gene id: 1842532:A7E78_RS10485
uniprot id: A0A1L3GQN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1842532:A7E78 RS07630
gene id: 1842532:A7E78_RS07630
uniprot id: A0A1L3GP60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1842532:A7E78 RS13635
gene id: 1842532:A7E78_RS13635
uniprot id: A0A1L3GS34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1842532:A7E78 RS06520
gene id: 1842532:A7E78_RS06520
uniprot id: A0A1L3GNL5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1842532:A7E78 RS02370
gene id: 1842532:A7E78_RS02370
uniprot id: A0A1L3GLL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1842532:A7E78 RS12305
gene id: 1842532:A7E78_RS12305
uniprot id: A0A1L3GRG0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1842532:A7E78 RS03020
gene id: 1842532:A7E78_RS03020
uniprot id: A0A1L3GLS7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS10335
gene id: 1842532:A7E78_RS10335
uniprot id: A0A1L3GQG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1842532:A7E78 RS07745
gene id: 1842532:A7E78_RS07745
uniprot id: A0A1L3GP57
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1842532:A7E78 RS12265
gene id: 1842532:A7E78_RS12265
uniprot id: A0A1L3GRI7
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS00895
gene id: 1842532:A7E78_RS00895
uniprot id: A0A1L3GKU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1842532:A7E78 RS12270
gene id: 1842532:A7E78_RS12270
uniprot id: A0A1L3GRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1842532:A7E78 RS08370
gene id: 1842532:A7E78_RS08370
uniprot id: A0A1L3GT05
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1842532:A7E78 RS00195
gene id: 1842532:A7E78_RS00195
uniprot id: A0A1L3GKG6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1842532:A7E78 RS12280
gene id: 1842532:A7E78_RS12280
uniprot id: A0A1L3GRF3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1842532:A7E78 RS01235
gene id: 1842532:A7E78_RS01235
uniprot id: A0A1L3GSR2
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1842532:A7E78 RS13730
gene id: 1842532:A7E78_RS13730
uniprot id: A0A1L3GS67
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1842532:A7E78 RS10820
gene id: 1842532:A7E78_RS10820
uniprot id: A0A1L3GQQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

1842532:A7E78 RS08385
gene id: 1842532:A7E78_RS08385
uniprot id: A0A1L3GPF9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS04930
gene id: 1842532:A7E78_RS04930
uniprot id: A0A1L3GMV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1842532:A7E78 RS08750
gene id: 1842532:A7E78_RS08750
uniprot id: A0A1L3GPR2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1842532:A7E78 RS04545
gene id: 1842532:A7E78_RS04545
uniprot id: A0A1L3GNB1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1842532:A7E78 RS06445
gene id: 1842532:A7E78_RS06445
uniprot id: A0A1L3GPA0
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1842532:A7E78 RS14170
gene id: 1842532:A7E78_RS14170
uniprot id: A0A1L3GT70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1842532:A7E78 RS10460
gene id: 1842532:A7E78_RS10460
uniprot id: A0A1L3GQI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1842532:A7E78 RS00730
gene id: 1842532:A7E78_RS00730
uniprot id: A0A1L3GKV5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1842532:A7E78 RS02425
gene id: 1842532:A7E78_RS02425
uniprot id: A0A1L3GLM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1842532:A7E78 RS01040
gene id: 1842532:A7E78_RS01040
uniprot id: A0A1L3GKV4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1842532:A7E78 RS11670
gene id: 1842532:A7E78_RS11670
uniprot id: A0A1L3GR42
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS08835
gene id: 1842532:A7E78_RS08835
uniprot id: A0A1L3GPN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

1842532:A7E78 RS03640
gene id: 1842532:A7E78_RS03640
uniprot id: A0A1L3GM27
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1842532:A7E78 RS13670
gene id: 1842532:A7E78_RS13670
uniprot id: A0A1L3GT61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1842532:A7E78 RS07275
gene id: 1842532:A7E78_RS07275
uniprot id: A0A1L3GNX6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1842532:A7E78 RS04155
gene id: 1842532:A7E78_RS04155
uniprot id: A0A1L3GMG9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1842532:A7E78 RS12935
gene id: 1842532:A7E78_RS12935
uniprot id: A0A1L3GRS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS10075
gene id: 1842532:A7E78_RS10075
uniprot id: A0A1L3GQK6
names: Similarity
messages: Belongs to the SUI1 family.

1842532:A7E78 RS08170
gene id: 1842532:A7E78_RS08170
uniprot id: A0A1L3GPD1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1842532:A7E78 RS08205
gene id: 1842532:A7E78_RS08205
uniprot id: A0A1L3GPE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS09025
gene id: 1842532:A7E78_RS09025
uniprot id: A0A1L3GPS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1842532:A7E78 RS07200
gene id: 1842532:A7E78_RS07200
uniprot id: A0A1L3GP13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1842532:A7E78 RS11260
gene id: 1842532:A7E78_RS11260
uniprot id: A0A1L3GQY2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1842532:A7E78 RS01080
gene id: 1842532:A7E78_RS01080
uniprot id: A0A1L3GKU1
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS09130
gene id: 1842532:A7E78_RS09130
uniprot id: A0A1L3GPY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1842532:A7E78 RS03630
gene id: 1842532:A7E78_RS03630
uniprot id: A0A1L3GM76
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1842532:A7E78 RS12920
gene id: 1842532:A7E78_RS12920
uniprot id: A0A1L3GRU1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1842532:A7E78 RS08155
gene id: 1842532:A7E78_RS08155
uniprot id: A0A1L3GPF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1842532:A7E78 RS01970
gene id: 1842532:A7E78_RS01970
uniprot id: A0A1L3GLB7
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1842532:A7E78 RS10605
gene id: 1842532:A7E78_RS10605
uniprot id: A0A1L3GQP8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS08330
gene id: 1842532:A7E78_RS08330
uniprot id: A0A1L3GPH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1842532:A7E78 RS00890
gene id: 1842532:A7E78_RS00890
uniprot id: A0A1L3GKV9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1842532:A7E78 RS10570
gene id: 1842532:A7E78_RS10570
uniprot id: A0A1L3GRE5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1842532:A7E78 RS03790
gene id: 1842532:A7E78_RS03790
uniprot id: A0A1L3GM65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1842532:A7E78 RS05540
gene id: 1842532:A7E78_RS05540
uniprot id: A0A1L3GN28
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1842532:A7E78 RS14555
gene id: 1842532:A7E78_RS14555
uniprot id: A0A1L3GSJ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS02385
gene id: 1842532:A7E78_RS02385
uniprot id: A0A1L3GM93
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1842532:A7E78 RS04970
gene id: 1842532:A7E78_RS04970
uniprot id: A0A1L3GMS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1842532:A7E78 RS08495
gene id: 1842532:A7E78_RS08495
uniprot id: A0A1L3GPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1842532:A7E78 RS13950
gene id: 1842532:A7E78_RS13950
uniprot id: A0A1L3GSD3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1842532:A7E78 RS10440
gene id: 1842532:A7E78_RS10440
uniprot id: A0A1L3GQK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1842532:A7E78 RS00725
gene id: 1842532:A7E78_RS00725
uniprot id: A0A1L3GKR9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1842532:A7E78 RS12040
gene id: 1842532:A7E78_RS12040
uniprot id: A0A1L3GRC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1842532:A7E78 RS05515
gene id: 1842532:A7E78_RS05515
uniprot id: A0A1L3GN27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1842532:A7E78 RS14420
gene id: 1842532:A7E78_RS14420
uniprot id: A0A1L3GSI7
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1842532:A7E78 RS05615
gene id: 1842532:A7E78_RS05615
uniprot id: A0A1L3GN34
names: Similarity
messages: Belongs to the Fmt family.

1842532:A7E78 RS09355
gene id: 1842532:A7E78_RS09355
uniprot id: A0A1L3GPY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1842532:A7E78 RS08795
gene id: 1842532:A7E78_RS08795
uniprot id: A0A1L3GPQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1842532:A7E78 RS09730
gene id: 1842532:A7E78_RS09730
uniprot id: A0A1L3GQ96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1842532:A7E78 RS13125
gene id: 1842532:A7E78_RS13125
uniprot id: A0A1L3GRW2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1842532:A7E78 RS01995
gene id: 1842532:A7E78_RS01995
uniprot id: A0A1L3GLB2
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS03745
gene id: 1842532:A7E78_RS03745
uniprot id: A0A1L3GM38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1842532:A7E78 RS13905
gene id: 1842532:A7E78_RS13905
uniprot id: A0A1L3GSZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1842532:A7E78 RS03430
gene id: 1842532:A7E78_RS03430
uniprot id: A0A1L3GM03
names: Similarity
messages: Belongs to the threonine synthase family.

1842532:A7E78 RS14335
gene id: 1842532:A7E78_RS14335
uniprot id: A0A1L3GSI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS03400
gene id: 1842532:A7E78_RS03400
uniprot id: A0A1L3GLZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS10560
gene id: 1842532:A7E78_RS10560
uniprot id: A0A1L3GQJ4
names: Subcellular Location Annotation
messages: Cytoplasm

1842532:A7E78 RS12865
gene id: 1842532:A7E78_RS12865
uniprot id: A0A1L3GRR8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1842532:A7E78 RS04315
gene id: 1842532:A7E78_RS04315
uniprot id: A0A1L3GMK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1842532:A7E78 RS14255
gene id: 1842532:A7E78_RS14255
uniprot id: A0A1L3GSE8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1842532:A7E78 RS07780
gene id: 1842532:A7E78_RS07780
uniprot id: A0A1L3GP51
names: Similarity
messages: Belongs to the peptidase M16 family.

1842532:A7E78 RS13795
gene id: 1842532:A7E78_RS13795
uniprot id: A0A1L3GS82
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1842532:A7E78 RS01935
gene id: 1842532:A7E78_RS01935
uniprot id: A0A1L3GLA2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1842532:A7E78 RS06570
gene id: 1842532:A7E78_RS06570
uniprot id: A0A1L3GNK8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1842532:A7E78 RS02785
gene id: 1842532:A7E78_RS02785
uniprot id: A0A1L3GLN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1842532:A7E78 RS07895
gene id: 1842532:A7E78_RS07895
uniprot id: A0A1L3GPC0
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS00020
gene id: 1842532:A7E78_RS00020
uniprot id: A0A1L3GKB4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1842532:A7E78 RS01030
gene id: 1842532:A7E78_RS01030
uniprot id: A0A1L3GKW1
names: Similarity
messages: Belongs to the Gfa family.

1842532:A7E78 RS01620
gene id: 1842532:A7E78_RS01620
uniprot id: A0A1L3GL97
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1842532:A7E78 RS08950
gene id: 1842532:A7E78_RS08950
uniprot id: A0A1L3GPQ7
names: Similarity
messages: Belongs to the IMPACT family.

1842532:A7E78 RS00590
gene id: 1842532:A7E78_RS00590
uniprot id: A0A1L3GKP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1842532:A7E78 RS04615
gene id: 1842532:A7E78_RS04615
uniprot id: A0A1L3GMP7
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS01940
gene id: 1842532:A7E78_RS01940
uniprot id: A0A1L3GLA4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS03135
gene id: 1842532:A7E78_RS03135
uniprot id: A0A1L3GLU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1842532:A7E78 RS06615
gene id: 1842532:A7E78_RS06615
uniprot id: A0A1L3GNJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1842532:A7E78 RS07505
gene id: 1842532:A7E78_RS07505
uniprot id: A0A1L3GP15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1842532:A7E78 RS06985
gene id: 1842532:A7E78_RS06985
uniprot id: A0A1L3GNT5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS05535
gene id: 1842532:A7E78_RS05535
uniprot id: A0A1L3GNT6
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1842532:A7E78 RS03510
gene id: 1842532:A7E78_RS03510
uniprot id: A0A1L3GM56
names: Similarity
messages: Belongs to the GSP E family.

1842532:A7E78 RS03980
gene id: 1842532:A7E78_RS03980
uniprot id: A0A1L3GM78
names: Similarity
messages: Belongs to the ArsC family.

1842532:A7E78 RS14550
gene id: 1842532:A7E78_RS14550
uniprot id: A0A1L3GSJ7
names: Similarity
messages: Belongs to the ribF family.

1842532:A7E78 RS10800
gene id: 1842532:A7E78_RS10800
uniprot id: A0A1L3GRI8
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS01585
gene id: 1842532:A7E78_RS01585
uniprot id: A0A1L3GL68
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1842532:A7E78 RS06140
gene id: 1842532:A7E78_RS06140
uniprot id: A0A1L3GNI3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1842532:A7E78 RS07665
gene id: 1842532:A7E78_RS07665
uniprot id: A0A1L3GP46
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1842532:A7E78 RS10835
gene id: 1842532:A7E78_RS10835
uniprot id: A0A1L3GQT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1842532:A7E78 RS08305
gene id: 1842532:A7E78_RS08305
uniprot id: A0A1L3GQ68
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1842532:A7E78 RS01180
gene id: 1842532:A7E78_RS01180
uniprot id: A0A1L3GL23
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1842532:A7E78 RS02780
gene id: 1842532:A7E78_RS02780
uniprot id: A0A1L3GSS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BioW family.
messages: Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
messages: Homodimer.

1842532:A7E78 RS00030
gene id: 1842532:A7E78_RS00030
uniprot id: A0A1L3GKI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1842532:A7E78 RS03665
gene id: 1842532:A7E78_RS03665
uniprot id: A0A1L3GM89
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1842532:A7E78 RS06535
gene id: 1842532:A7E78_RS06535
uniprot id: A0A1L3GNL3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1842532:A7E78 RS08715
gene id: 1842532:A7E78_RS08715
uniprot id: A0A1L3GQE6
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1842532:A7E78 RS04890
gene id: 1842532:A7E78_RS04890
uniprot id: A0A1L3GMQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1842532:A7E78 RS15385
gene id: 1842532:A7E78_RS15385
uniprot id: A0A1L3GT13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1842532:A7E78 RS05090
gene id: 1842532:A7E78_RS05090
uniprot id: A0A1L3GMY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1842532:A7E78 RS10840
gene id: 1842532:A7E78_RS10840
uniprot id: A0A1L3GQP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1842532:A7E78 RS12180
gene id: 1842532:A7E78_RS12180
uniprot id: A0A1L3GRF4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1842532:A7E78 RS05400
gene id: 1842532:A7E78_RS05400
uniprot id: A0A1L3GN10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1842532:A7E78 RS11400
gene id: 1842532:A7E78_RS11400
uniprot id: A0A1L3GRU0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1842532:A7E78 RS11490
gene id: 1842532:A7E78_RS11490
uniprot id: A0A1L3GR60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1842532:A7E78 RS06205
gene id: 1842532:A7E78_RS06205
uniprot id: A0A1L3GNJ3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1842532:A7E78 RS01295
gene id: 1842532:A7E78_RS01295
uniprot id: A0A1L3GKZ0
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS01240
gene id: 1842532:A7E78_RS01240
uniprot id: A0A1L3GL09
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1842532:A7E78 RS05010
gene id: 1842532:A7E78_RS05010
uniprot id: A0A1L3GMW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1842532:A7E78 RS04725
gene id: 1842532:A7E78_RS04725
uniprot id: A0A1L3GNE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1842532:A7E78 RS13435
gene id: 1842532:A7E78_RS13435
uniprot id: A0A1L3GS20
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS11270
gene id: 1842532:A7E78_RS11270
uniprot id: A0A1L3GR03
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1842532:A7E78 RS01880
gene id: 1842532:A7E78_RS01880
uniprot id: A0A1L3GLD1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1842532:A7E78 RS05225
gene id: 1842532:A7E78_RS05225
uniprot id: A0A1L3GMY1
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1842532:A7E78 RS11815
gene id: 1842532:A7E78_RS11815
uniprot id: A0A1L3GR80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1842532:A7E78 RS13220
gene id: 1842532:A7E78_RS13220
uniprot id: A0A1L3GRX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS06195
gene id: 1842532:A7E78_RS06195
uniprot id: A0A1L3GND4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1842532:A7E78 RS04200
gene id: 1842532:A7E78_RS04200
uniprot id: A0A1L3GST4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1842532:A7E78 RS02420
gene id: 1842532:A7E78_RS02420
uniprot id: A0A1L3GLK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1842532:A7E78 RS06680
gene id: 1842532:A7E78_RS06680
uniprot id: A0A1L3GNM5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1842532:A7E78 RS03625
gene id: 1842532:A7E78_RS03625
uniprot id: A0A1L3GM35
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1842532:A7E78 RS06790
gene id: 1842532:A7E78_RS06790
uniprot id: A0A1L3GNP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1842532:A7E78 RS05035
gene id: 1842532:A7E78_RS05035
uniprot id: A0A1L3GMX5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS06745
gene id: 1842532:A7E78_RS06745
uniprot id: A0A1L3GNR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1842532:A7E78 RS10595
gene id: 1842532:A7E78_RS10595
uniprot id: A0A1L3GQP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS07685
gene id: 1842532:A7E78_RS07685
uniprot id: A0A1L3GP70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1842532:A7E78 RS03685
gene id: 1842532:A7E78_RS03685
uniprot id: A0A1L3GM44
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1842532:A7E78 RS13930
gene id: 1842532:A7E78_RS13930
uniprot id: A0A1L3GS93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1842532:A7E78 RS00620
gene id: 1842532:A7E78_RS00620
uniprot id: A0A1L3GKN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1842532:A7E78 RS02990
gene id: 1842532:A7E78_RS02990
uniprot id: A0A1L3GLR9
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS10375
gene id: 1842532:A7E78_RS10375
uniprot id: A0A1L3GQJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1842532:A7E78 RS00010
gene id: 1842532:A7E78_RS00010
uniprot id: A0A1L3GKF6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1842532:A7E78 RS08340
gene id: 1842532:A7E78_RS08340
uniprot id: A0A1L3GPI5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1842532:A7E78 RS03115
gene id: 1842532:A7E78_RS03115
uniprot id: A0A1L3GLV1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1842532:A7E78 RS02485
gene id: 1842532:A7E78_RS02485
uniprot id: A0A1L3GLP0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1842532:A7E78 RS04335
gene id: 1842532:A7E78_RS04335
uniprot id: A0A1L3GMF7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1842532:A7E78 RS12055
gene id: 1842532:A7E78_RS12055
uniprot id: A0A1L3GRD4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1842532:A7E78 RS08560
gene id: 1842532:A7E78_RS08560
uniprot id: A0A1L3GPQ1
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1842532:A7E78 RS12515
gene id: 1842532:A7E78_RS12515
uniprot id: A0A1L3GRK6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1842532:A7E78 RS07515
gene id: 1842532:A7E78_RS07515
uniprot id: A0A1L3GP34
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1842532:A7E78 RS13925
gene id: 1842532:A7E78_RS13925
uniprot id: A0A1L3GS99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1842532:A7E78 RS08910
gene id: 1842532:A7E78_RS08910
uniprot id: A0A1L3GPU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS12925
gene id: 1842532:A7E78_RS12925
uniprot id: A0A1L3GRS3
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1842532:A7E78 RS09455
gene id: 1842532:A7E78_RS09455
uniprot id: A0A1L3GPZ0
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS09565
gene id: 1842532:A7E78_RS09565
uniprot id: A0A1L3GQ10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1842532:A7E78 RS11985
gene id: 1842532:A7E78_RS11985
uniprot id: A0A1L3GRD6
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1842532:A7E78 RS05100
gene id: 1842532:A7E78_RS05100
uniprot id: A0A1L3GMT7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1842532:A7E78 RS10690
gene id: 1842532:A7E78_RS10690
uniprot id: A0A1L3GQM2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS09415
gene id: 1842532:A7E78_RS09415
uniprot id: A0A1L3GQ35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Belongs to the complex I 30 kDa subunit family.
messages: Belongs to the complex I 49 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 20 kDa subunit family.
messages: In the central section; belongs to the complex I 30 kDa subunit family.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 is composed of about 13 different subunits. Subunits NuoBCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1842532:A7E78 RS07860
gene id: 1842532:A7E78_RS07860
uniprot id: A0A1L3GP82
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

1842532:A7E78 RS12065
gene id: 1842532:A7E78_RS12065
uniprot id: A0A1L3GRB6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1842532:A7E78 RS14445
gene id: 1842532:A7E78_RS14445
uniprot id: A0A1L3GSL8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1842532:A7E78 RS02520
gene id: 1842532:A7E78_RS02520
uniprot id: A0A1L3GLP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1842532:A7E78 RS12070
gene id: 1842532:A7E78_RS12070
uniprot id: A0A1L3GRL4
names: Subunit
messages: Homodimer.

1842532:A7E78 RS13320
gene id: 1842532:A7E78_RS13320
uniprot id: A0A1L3GS00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1842532:A7E78 RS01990
gene id: 1842532:A7E78_RS01990
uniprot id: A0A1L3GLF1
names: Similarity
messages: Belongs to the UPF0270 family.

1842532:A7E78 RS10660
gene id: 1842532:A7E78_RS10660
uniprot id: A0A1L3GQQ7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1842532:A7E78 RS02795
gene id: 1842532:A7E78_RS02795
uniprot id: A0A1L3GLT6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1842532:A7E78 RS09275
gene id: 1842532:A7E78_RS09275
uniprot id: A0A1L3GPY7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1842532:A7E78 RS01700
gene id: 1842532:A7E78_RS01700
uniprot id: A0A1L3GL86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS01795
gene id: 1842532:A7E78_RS01795
uniprot id: A0A1L3GLD6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1842532:A7E78 RS13515
gene id: 1842532:A7E78_RS13515
uniprot id: A0A1L3GS55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1842532:A7E78 RS08840
gene id: 1842532:A7E78_RS08840
uniprot id: A0A1L3GPQ5
names: Similarity
messages: Belongs to the GSP E family.

1842532:A7E78 RS02210
gene id: 1842532:A7E78_RS02210
uniprot id: A0A1L3GLF9
names: Similarity
messages: Belongs to the creatininase superfamily.

1842532:A7E78 RS13910
gene id: 1842532:A7E78_RS13910
uniprot id: A0A1L3GS97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1842532:A7E78 RS09585
gene id: 1842532:A7E78_RS09585
uniprot id: A0A1L3GQ71
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1842532:A7E78 RS04995
gene id: 1842532:A7E78_RS04995
uniprot id: A0A1L3GNI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS00995
gene id: 1842532:A7E78_RS00995
uniprot id: A0A1L3GTF5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS04475
gene id: 1842532:A7E78_RS04475
uniprot id: A0A1L3GMM6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1842532:A7E78 RS01855
gene id: 1842532:A7E78_RS01855
uniprot id: A0A1L3GLD4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1842532:A7E78 RS13475
gene id: 1842532:A7E78_RS13475
uniprot id: A0A1L3GS19
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1842532:A7E78 RS08710
gene id: 1842532:A7E78_RS08710
uniprot id: A0A1L3GPM3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1842532:A7E78 RS07385
gene id: 1842532:A7E78_RS07385
uniprot id: A0A1L3GNZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1842532:A7E78 RS14125
gene id: 1842532:A7E78_RS14125
uniprot id: A0A1L3GSJ2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1842532:A7E78 RS09640
gene id: 1842532:A7E78_RS09640
uniprot id: A0A1L3GQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1842532:A7E78 RS05585
gene id: 1842532:A7E78_RS05585
uniprot id: A0A1L3GN31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1842532:A7E78 RS05135
gene id: 1842532:A7E78_RS05135
uniprot id: A0A1L3GMW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1842532:A7E78 RS03125
gene id: 1842532:A7E78_RS03125
uniprot id: A0A1L3GLY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1842532:A7E78 RS05465
gene id: 1842532:A7E78_RS05465
uniprot id: A0A1L3GN64
names: Similarity
messages: Belongs to the MotB family.

1842532:A7E78 RS02140
gene id: 1842532:A7E78_RS02140
uniprot id: A0A1L3GM53
names: Similarity
messages: Belongs to the peptidase M1 family.

1842532:A7E78 RS00025
gene id: 1842532:A7E78_RS00025
uniprot id: A0A1L3GKE7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1842532:A7E78 RS02805
gene id: 1842532:A7E78_RS02805
uniprot id: A0A1L3GLN9
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS11555
gene id: 1842532:A7E78_RS11555
uniprot id: A0A1L3GR51
names: Similarity
messages: Belongs to the AOR/FOR family.

1842532:A7E78 RS09820
gene id: 1842532:A7E78_RS09820
uniprot id: A0A1L3GQ63
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1842532:A7E78 RS08410
gene id: 1842532:A7E78_RS08410
uniprot id: A0A1L3GSZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1842532:A7E78 RS14140
gene id: 1842532:A7E78_RS14140
uniprot id: A0A1L3GSC9
names: Similarity
messages: Belongs to the GARS family.

1842532:A7E78 RS12895
gene id: 1842532:A7E78_RS12895
uniprot id: A0A1L3GRT5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1842532:A7E78 RS10765
gene id: 1842532:A7E78_RS10765
uniprot id: A0A1L3GT49
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1842532:A7E78 RS02855
gene id: 1842532:A7E78_RS02855
uniprot id: A0A1L3GLU5
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1842532:A7E78 RS14355
gene id: 1842532:A7E78_RS14355
uniprot id: A0A1L3GSH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

1842532:A7E78 RS02305
gene id: 1842532:A7E78_RS02305
uniprot id: A0A1L3GLI5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1842532:A7E78 RS02015
gene id: 1842532:A7E78_RS02015
uniprot id: A0A1L3GLC9
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS10155
gene id: 1842532:A7E78_RS10155
uniprot id: A0A1L3GQH6
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS00855
gene id: 1842532:A7E78_RS00855
uniprot id: A0A1L3GKT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1842532:A7E78 RS01440
gene id: 1842532:A7E78_RS01440
uniprot id: A0A1L3GLU4
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS13545
gene id: 1842532:A7E78_RS13545
uniprot id: A0A1L3GS39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1842532:A7E78 RS05410
gene id: 1842532:A7E78_RS05410
uniprot id: A0A1L3GN01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1842532:A7E78 RS05430
gene id: 1842532:A7E78_RS05430
uniprot id: A0A1L3GN05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1842532:A7E78 RS10240
gene id: 1842532:A7E78_RS10240
uniprot id: A0A1L3GQE3
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1842532:A7E78 RS02935
gene id: 1842532:A7E78_RS02935
uniprot id: A0A1L3GLQ8
names: Similarity
messages: Belongs to the GSP E family.

1842532:A7E78 RS12750
gene id: 1842532:A7E78_RS12750
uniprot id: A0A1L3GRP1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1842532:A7E78 RS09895
gene id: 1842532:A7E78_RS09895
uniprot id: A0A1L3GQ79
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS07990
gene id: 1842532:A7E78_RS07990
uniprot id: A0A1L3GPB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1842532:A7E78 RS06675
gene id: 1842532:A7E78_RS06675
uniprot id: A0A1L3GPD6
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

1842532:A7E78 RS01285
gene id: 1842532:A7E78_RS01285
uniprot id: A0A1L3GL40
names: Subcellular Location Annotation
messages: Cytoplasm

1842532:A7E78 RS08845
gene id: 1842532:A7E78_RS08845
uniprot id: A0A1L3GPT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1842532:A7E78 RS02590
gene id: 1842532:A7E78_RS02590
uniprot id: A0A1L3GLK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1842532:A7E78 RS08730
gene id: 1842532:A7E78_RS08730
uniprot id: A0A1L3GPL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1842532:A7E78 RS06215
gene id: 1842532:A7E78_RS06215
uniprot id: A0A1L3GNE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1842532:A7E78 RS05265
gene id: 1842532:A7E78_RS05265
uniprot id: A0A1L3GMW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1842532:A7E78 RS09325
gene id: 1842532:A7E78_RS09325
uniprot id: A0A1L3GPX6
names: Subcellular Location Annotation
messages: Membrane

1842532:A7E78 RS02605
gene id: 1842532:A7E78_RS02605
uniprot id: A0A1L3GLQ6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1842532:A7E78 RS01630
gene id: 1842532:A7E78_RS01630
uniprot id: A0A1L3GL74
names: Similarity
messages: Belongs to the YicC/YloC family.

1842532:A7E78 RS07800
gene id: 1842532:A7E78_RS07800
uniprot id: A0A1L3GP66
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1842532:A7E78 RS04975
gene id: 1842532:A7E78_RS04975
uniprot id: A0A1L3GMT0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1842532:A7E78 RS09315
gene id: 1842532:A7E78_RS09315
uniprot id: A0A1L3GPY1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1842532:A7E78 RS07450
gene id: 1842532:A7E78_RS07450
uniprot id: A0A1L3GPR7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1842532:A7E78 RS05030
gene id: 1842532:A7E78_RS05030
uniprot id: A0A1L3GMU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1842532:A7E78 RS06095
gene id: 1842532:A7E78_RS06095
uniprot id: A0A1L3GNC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1842532:A7E78 RS11915
gene id: 1842532:A7E78_RS11915
uniprot id: A0A1L3GRA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1842532:A7E78 RS07290
gene id: 1842532:A7E78_RS07290
uniprot id: A0A1L3GNZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1842532:A7E78 RS07190
gene id: 1842532:A7E78_RS07190
uniprot id: A0A1L3GNW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1842532:A7E78 RS02495
gene id: 1842532:A7E78_RS02495
uniprot id: A0A1L3GSX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.