1827580:DC008 RS11585
gene id: 1827580:DC008_RS11585
uniprot id: A0A2S1ICE2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1827580:DC008 RS27820
gene id: 1827580:DC008_RS27820
uniprot id: A0A2S1IKU4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1827580:DC008 RS04435
gene id: 1827580:DC008_RS04435
uniprot id: A0A2S1I8Q1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1827580:DC008 RS20900
gene id: 1827580:DC008_RS20900
uniprot id: A0A2S1IH10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1827580:DC008 RS25065
gene id: 1827580:DC008_RS25065
uniprot id: A0A2S1IJ85
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1827580:DC008 RS28790
gene id: 1827580:DC008_RS28790
uniprot id: A0A2S1IL07
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1827580:DC008 RS28505
gene id: 1827580:DC008_RS28505
uniprot id: A0A2S1IKV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

1827580:DC008 RS17660
gene id: 1827580:DC008_RS17660
uniprot id: A0A2S1IFB6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1827580:DC008 RS07995
gene id: 1827580:DC008_RS07995
uniprot id: A0A2S1IAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1827580:DC008 RS21710
gene id: 1827580:DC008_RS21710
uniprot id: A0A2S1IHE1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1827580:DC008 RS11015
gene id: 1827580:DC008_RS11015
uniprot id: A0A2S1IC51
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1827580:DC008 RS04365
gene id: 1827580:DC008_RS04365
uniprot id: A0A2S1IPB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1827580:DC008 RS21895
gene id: 1827580:DC008_RS21895
uniprot id: A0A2S1IHJ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1827580:DC008 RS26190
gene id: 1827580:DC008_RS26190
uniprot id: A0A2S1IJQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1827580:DC008 RS22845
gene id: 1827580:DC008_RS22845
uniprot id: A0A2S1II08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1827580:DC008 RS20795
gene id: 1827580:DC008_RS20795
uniprot id: A0A2S1IH08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1827580:DC008 RS18565
gene id: 1827580:DC008_RS18565
uniprot id: A0A2S1IFS0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1827580:DC008 RS22270
gene id: 1827580:DC008_RS22270
uniprot id: A0A2S1IHQ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1827580:DC008 RS16450
gene id: 1827580:DC008_RS16450
uniprot id: A0A2S1IES7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1827580:DC008 RS07925
gene id: 1827580:DC008_RS07925
uniprot id: A0A2S1IAK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1827580:DC008 RS15350
gene id: 1827580:DC008_RS15350
uniprot id: A0A2S1IEE5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1827580:DC008 RS34430
gene id: 1827580:DC008_RS34430
uniprot id: A0A2S1INU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1827580:DC008 RS20865
gene id: 1827580:DC008_RS20865
uniprot id: A0A2S1IQ56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1827580:DC008 RS10035
gene id: 1827580:DC008_RS10035
uniprot id: A0A2S1IBS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1827580:DC008 RS07085
gene id: 1827580:DC008_RS07085
uniprot id: A0A2S1IA80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1827580:DC008 RS06035
gene id: 1827580:DC008_RS06035
uniprot id: A0A2S1IA34
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1827580:DC008 RS20835
gene id: 1827580:DC008_RS20835
uniprot id: A0A2S1IHJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1827580:DC008 RS23290
gene id: 1827580:DC008_RS23290
uniprot id: A0A2S1II73
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1827580:DC008 RS20750
gene id: 1827580:DC008_RS20750
uniprot id: A0A2S1IGZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1827580:DC008 RS04270
gene id: 1827580:DC008_RS04270
uniprot id: A0A2S1I8M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1827580:DC008 RS12750
gene id: 1827580:DC008_RS12750
uniprot id: A0A2S1ICY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1827580:DC008 RS08760
gene id: 1827580:DC008_RS08760
uniprot id: A0A2S1IB69
names: Similarity
messages: Belongs to the YggT family.

1827580:DC008 RS28350
gene id: 1827580:DC008_RS28350
uniprot id: A0A2S1IL33
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1827580:DC008 RS15795
gene id: 1827580:DC008_RS15795
uniprot id: A0A2S1IEL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

1827580:DC008 RS02245
gene id: 1827580:DC008_RS02245
uniprot id: A0A2S1I7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1827580:DC008 RS20895
gene id: 1827580:DC008_RS20895
uniprot id: A0A2S1IHK6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1827580:DC008 RS30740
gene id: 1827580:DC008_RS30740
uniprot id: A0A2S1ILY3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1827580:DC008 RS09165
gene id: 1827580:DC008_RS09165
uniprot id: A0A2S1IB65
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1827580:DC008 RS06030
gene id: 1827580:DC008_RS06030
uniprot id: A0A2S1I9J4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1827580:DC008 RS22470
gene id: 1827580:DC008_RS22470
uniprot id: A0A2S1IQ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1827580:DC008 RS21180
gene id: 1827580:DC008_RS21180
uniprot id: A0A2S1IH48
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1827580:DC008 RS05565
gene id: 1827580:DC008_RS05565
uniprot id: A0A2S1I9H1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1827580:DC008 RS17215
gene id: 1827580:DC008_RS17215
uniprot id: A0A2S1IF50
names: Subcellular Location Annotation
messages: Membrane

1827580:DC008 RS19745
gene id: 1827580:DC008_RS19745
uniprot id: A0A2S1IQA3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1827580:DC008 RS21415
gene id: 1827580:DC008_RS21415
uniprot id: A0A2S1IHB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1827580:DC008 RS29505
gene id: 1827580:DC008_RS29505
uniprot id: A0A2S1ILG1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1827580:DC008 RS05730
gene id: 1827580:DC008_RS05730
uniprot id: A0A2S1I9E8
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1827580:DC008 RS20880
gene id: 1827580:DC008_RS20880
uniprot id: A0A2S1IGZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1827580:DC008 RS19575
gene id: 1827580:DC008_RS19575
uniprot id: A0A2S1IGB9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1827580:DC008 RS24000
gene id: 1827580:DC008_RS24000
uniprot id: A0A2S1IIK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1827580:DC008 RS06240
gene id: 1827580:DC008_RS06240
uniprot id: A0A2S1I9N6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1827580:DC008 RS13035
gene id: 1827580:DC008_RS13035
uniprot id: A0A2S1ID50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1827580:DC008 RS11205
gene id: 1827580:DC008_RS11205
uniprot id: A0A2S1IC79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1827580:DC008 RS33535
gene id: 1827580:DC008_RS33535
uniprot id: A0A2S1INE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1827580:DC008 RS20875
gene id: 1827580:DC008_RS20875
uniprot id: A0A2S1IGZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1827580:DC008 RS17935
gene id: 1827580:DC008_RS17935
uniprot id: A0A2S1IFK7
names: Similarity
messages: Belongs to the peptidase M18 family.

1827580:DC008 RS07005
gene id: 1827580:DC008_RS07005
uniprot id: A0A2S1IA38
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1827580:DC008 RS24990
gene id: 1827580:DC008_RS24990
uniprot id: A0A2S1IJ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1827580:DC008 RS25375
gene id: 1827580:DC008_RS25375
uniprot id: A0A2S1IJA2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1827580:DC008 RS07680
gene id: 1827580:DC008_RS07680
uniprot id: A0A2S1IAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1827580:DC008 RS23950
gene id: 1827580:DC008_RS23950
uniprot id: A0A2S1III9
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1827580:DC008 RS20940
gene id: 1827580:DC008_RS20940
uniprot id: A0A2S1IH11
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1827580:DC008 RS12125
gene id: 1827580:DC008_RS12125
uniprot id: A0A2S1ID96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1827580:DC008 RS29455
gene id: 1827580:DC008_RS29455
uniprot id: A0A2S1ILB6
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1827580:DC008 RS20685
gene id: 1827580:DC008_RS20685
uniprot id: A0A2S1IGZ7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1827580:DC008 RS17555
gene id: 1827580:DC008_RS17555
uniprot id: A0A2S1IFB0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1827580:DC008 RS07830
gene id: 1827580:DC008_RS07830
uniprot id: A0A2S1IAH6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1827580:DC008 RS20175
gene id: 1827580:DC008_RS20175
uniprot id: A0A2S1IGM0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1827580:DC008 RS09555
gene id: 1827580:DC008_RS09555
uniprot id: A0A2S1IPJ9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1827580:DC008 RS20825
gene id: 1827580:DC008_RS20825
uniprot id: A0A2S1IGW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1827580:DC008 RS25655
gene id: 1827580:DC008_RS25655
uniprot id: A0A2S1IJG5
names: Similarity
messages: Belongs to the WXG100 family.

1827580:DC008 RS02515
gene id: 1827580:DC008_RS02515
uniprot id: A0A2S1I7P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1827580:DC008 RS05465
gene id: 1827580:DC008_RS05465
uniprot id: A0A2S1I9D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1827580:DC008 RS19340
gene id: 1827580:DC008_RS19340
uniprot id: A0A2S1IGA5
names: Similarity
messages: Belongs to the UPF0145 family.

1827580:DC008 RS08965
gene id: 1827580:DC008_RS08965
uniprot id: A0A2S1IBB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1827580:DC008 RS07790
gene id: 1827580:DC008_RS07790
uniprot id: A0A2S1IAH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1827580:DC008 RS15100
gene id: 1827580:DC008_RS15100
uniprot id: A0A2S1IE52
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1827580:DC008 RS05570
gene id: 1827580:DC008_RS05570
uniprot id: A0A2S1I9B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1827580:DC008 RS15445
gene id: 1827580:DC008_RS15445
uniprot id: A0A2S1IEB3
names: Subcellular Location Annotation
messages: Cytoplasm

1827580:DC008 RS14460
gene id: 1827580:DC008_RS14460
uniprot id: A0A2S1IE11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1827580:DC008 RS13040
gene id: 1827580:DC008_RS13040
uniprot id: A0A2S1ID75
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1827580:DC008 RS24850
gene id: 1827580:DC008_RS24850
uniprot id: A0A2S1IJF6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1827580:DC008 RS10205
gene id: 1827580:DC008_RS10205
uniprot id: A0A2S1IBV1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1827580:DC008 RS21720
gene id: 1827580:DC008_RS21720
uniprot id: A0A2S1IHH7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1827580:DC008 RS16480
gene id: 1827580:DC008_RS16480
uniprot id: A0A2S1IF02
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1827580:DC008 RS25280
gene id: 1827580:DC008_RS25280
uniprot id: A0A2S1IJD7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1827580:DC008 RS23160
gene id: 1827580:DC008_RS23160
uniprot id: A0A2S1II80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1827580:DC008 RS36245
gene id: 1827580:DC008_RS36245
uniprot id: A0A2S1IE85
names: Subcellular Location Annotation
messages: Cytoplasm

1827580:DC008 RS02630
gene id: 1827580:DC008_RS02630
uniprot id: A0A2S1I7R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1827580:DC008 RS07175
gene id: 1827580:DC008_RS07175
uniprot id: A0A2S1IAE0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1827580:DC008 RS21175
gene id: 1827580:DC008_RS21175
uniprot id: A0A2S1IH28
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1827580:DC008 RS18440
gene id: 1827580:DC008_RS18440
uniprot id: A0A2S1IFX8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1827580:DC008 RS31205
gene id: 1827580:DC008_RS31205
uniprot id: A0A2S1IM78
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1827580:DC008 RS11200
gene id: 1827580:DC008_RS11200
uniprot id: A0A2S1ICT2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1827580:DC008 RS31760
gene id: 1827580:DC008_RS31760
uniprot id: A0A2S1IMG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1827580:DC008 RS25595
gene id: 1827580:DC008_RS25595
uniprot id: A0A2S1IJF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1827580:DC008 RS04360
gene id: 1827580:DC008_RS04360
uniprot id: A0A2S1I8S9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1827580:DC008 RS05355
gene id: 1827580:DC008_RS05355
uniprot id: A0A2S1I9B2
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1827580:DC008 RS10970
gene id: 1827580:DC008_RS10970
uniprot id: A0A2S1IPL5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1827580:DC008 RS20250
gene id: 1827580:DC008_RS20250
uniprot id: A0A2S1IHA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1827580:DC008 RS30620
gene id: 1827580:DC008_RS30620
uniprot id: A0A2S1IM14
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1827580:DC008 RS13655
gene id: 1827580:DC008_RS13655
uniprot id: A0A2S1IDE5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1827580:DC008 RS17575
gene id: 1827580:DC008_RS17575
uniprot id: A0A2S1IFH9
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1827580:DC008 RS17510
gene id: 1827580:DC008_RS17510
uniprot id: A0A2S1IFE4
names: Similarity
messages: Belongs to the thioredoxin family.

1827580:DC008 RS12310
gene id: 1827580:DC008_RS12310
uniprot id: A0A2S1ICU9
names: Similarity
messages: Belongs to the universal stress protein A family.

1827580:DC008 RS12070
gene id: 1827580:DC008_RS12070
uniprot id: A0A2S1ICL6
names: Similarity
messages: Belongs to the citrate synthase family.

1827580:DC008 RS20930
gene id: 1827580:DC008_RS20930
uniprot id: A0A2S1IH04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1827580:DC008 RS24205
gene id: 1827580:DC008_RS24205
uniprot id: A0A2S1IIP7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1827580:DC008 RS20700
gene id: 1827580:DC008_RS20700
uniprot id: A0A2S1IGV2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1827580:DC008 RS06350
gene id: 1827580:DC008_RS06350
uniprot id: A0A2S1I9R9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1827580:DC008 RS20630
gene id: 1827580:DC008_RS20630
uniprot id: A0A2S1IGY8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1827580:DC008 RS03350
gene id: 1827580:DC008_RS03350
uniprot id: A0A2S1I8A8
names: Subcellular Location Annotation
messages: Membrane

1827580:DC008 RS24485
gene id: 1827580:DC008_RS24485
uniprot id: A0A2S1IJ88
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1827580:DC008 RS20145
gene id: 1827580:DC008_RS20145
uniprot id: A0A2S1IGN3
names: Subcellular Location Annotation
messages: Cytoplasm

1827580:DC008 RS25070
gene id: 1827580:DC008_RS25070
uniprot id: A0A2S1IJ76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1827580:DC008 RS20830
gene id: 1827580:DC008_RS20830
uniprot id: A0A2S1IGY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1827580:DC008 RS08625
gene id: 1827580:DC008_RS08625
uniprot id: A0A2S1IAW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1827580:DC008 RS21000
gene id: 1827580:DC008_RS21000
uniprot id: A0A2S1IH19
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1827580:DC008 RS20805
gene id: 1827580:DC008_RS20805
uniprot id: A0A2S1IH05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1827580:DC008 RS24070
gene id: 1827580:DC008_RS24070
uniprot id: A0A2S1IIM0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1827580:DC008 RS25130
gene id: 1827580:DC008_RS25130
uniprot id: A0A2S1IJ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1827580:DC008 RS20810
gene id: 1827580:DC008_RS20810
uniprot id: A0A2S1IGX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1827580:DC008 RS22730
gene id: 1827580:DC008_RS22730
uniprot id: A0A2S1IIF8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1827580:DC008 RS04265
gene id: 1827580:DC008_RS04265
uniprot id: A0A2S1I8X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1827580:DC008 RS23990
gene id: 1827580:DC008_RS23990
uniprot id: A0A2S1IIJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1827580:DC008 RS29460
gene id: 1827580:DC008_RS29460
uniprot id: A0A2S1ILD2
names: Similarity
messages: Belongs to the DDAH family.

1827580:DC008 RS10185
gene id: 1827580:DC008_RS10185
uniprot id: A0A2S1IBP7
names: Similarity
messages: Belongs to the CdaR family.

1827580:DC008 RS20855
gene id: 1827580:DC008_RS20855
uniprot id: A0A2S1IH14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1827580:DC008 RS11420
gene id: 1827580:DC008_RS11420
uniprot id: A0A2S1ICA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1827580:DC008 RS01855
gene id: 1827580:DC008_RS01855
uniprot id: A0A2S1I7I0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1827580:DC008 RS08510
gene id: 1827580:DC008_RS08510
uniprot id: A0A2S1IAV0
names: Subcellular Location Annotation
messages: Membrane

1827580:DC008 RS08790
gene id: 1827580:DC008_RS08790
uniprot id: A0A2S1IAY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1827580:DC008 RS05815
gene id: 1827580:DC008_RS05815
uniprot id: A0A2S1I9Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1827580:DC008 RS07560
gene id: 1827580:DC008_RS07560
uniprot id: A0A2S1IAH3
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1827580:DC008 RS19125
gene id: 1827580:DC008_RS19125
uniprot id: A0A2S1IG40
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1827580:DC008 RS23940
gene id: 1827580:DC008_RS23940
uniprot id: A0A2S1IIJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1827580:DC008 RS20195
gene id: 1827580:DC008_RS20195
uniprot id: A0A2S1IH94
names: Similarity
messages: Belongs to the peptidase C40 family.

1827580:DC008 RS10720
gene id: 1827580:DC008_RS10720
uniprot id: A0A2S1IC01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1827580:DC008 RS33560
gene id: 1827580:DC008_RS33560
uniprot id: A0A2S1ING6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1827580:DC008 RS11395
gene id: 1827580:DC008_RS11395
uniprot id: A0A2S1ICB9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1827580:DC008 RS28090
gene id: 1827580:DC008_RS28090
uniprot id: A0A2S1IKN5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1827580:DC008 RS12890
gene id: 1827580:DC008_RS12890
uniprot id: A0A2S1ID93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1827580:DC008 RS12060
gene id: 1827580:DC008_RS12060
uniprot id: A0A2S1ICM0
names: Subcellular Location Annotation
messages: Membrane

1827580:DC008 RS20845
gene id: 1827580:DC008_RS20845
uniprot id: A0A2S1IH18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1827580:DC008 RS08795
gene id: 1827580:DC008_RS08795
uniprot id: A0A2S1IBL8
names: Subcellular Location Annotation
messages: Membrane

1827580:DC008 RS15940
gene id: 1827580:DC008_RS15940
uniprot id: A0A2S1IEJ7
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1827580:DC008 RS04965
gene id: 1827580:DC008_RS04965
uniprot id: A0A2S1I915
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1827580:DC008 RS14345
gene id: 1827580:DC008_RS14345
uniprot id: A0A2S1IDX4
names: Subcellular Location Annotation
messages: Membrane

1827580:DC008 RS23025
gene id: 1827580:DC008_RS23025
uniprot id: A0A2S1II52
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1827580:DC008 RS19660
gene id: 1827580:DC008_RS19660
uniprot id: A0A2S1IGC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1827580:DC008 RS22400
gene id: 1827580:DC008_RS22400
uniprot id: A0A2S1IHS3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1827580:DC008 RS10725
gene id: 1827580:DC008_RS10725
uniprot id: A0A2S1IC17
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1827580:DC008 RS04950
gene id: 1827580:DC008_RS04950
uniprot id: A0A2S1I8Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1827580:DC008 RS05510
gene id: 1827580:DC008_RS05510
uniprot id: A0A2S1IPC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1827580:DC008 RS18740
gene id: 1827580:DC008_RS18740
uniprot id: A0A2S1IG23
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1827580:DC008 RS29040
gene id: 1827580:DC008_RS29040
uniprot id: A0A2S1IL52
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1827580:DC008 RS23120
gene id: 1827580:DC008_RS23120
uniprot id: A0A2S1II53
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1827580:DC008 RS10200
gene id: 1827580:DC008_RS10200
uniprot id: A0A2S1IBS5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1827580:DC008 RS20040
gene id: 1827580:DC008_RS20040
uniprot id: A0A2S1IGL5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1827580:DC008 RS10880
gene id: 1827580:DC008_RS10880
uniprot id: A0A2S1IC16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1827580:DC008 RS20925
gene id: 1827580:DC008_RS20925
uniprot id: A0A2S1IH02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1827580:DC008 RS15200
gene id: 1827580:DC008_RS15200
uniprot id: A0A2S1IE63
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1827580:DC008 RS05155
gene id: 1827580:DC008_RS05155
uniprot id: A0A2S1I930
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1827580:DC008 RS28705
gene id: 1827580:DC008_RS28705
uniprot id: A0A2S1IL12
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1827580:DC008 RS24015
gene id: 1827580:DC008_RS24015
uniprot id: A0A2S1IIL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1827580:DC008 RS05255
gene id: 1827580:DC008_RS05255
uniprot id: A0A2S1I952
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1827580:DC008 RS05705
gene id: 1827580:DC008_RS05705
uniprot id: A0A2S1I9E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1827580:DC008 RS32375
gene id: 1827580:DC008_RS32375
uniprot id: A0A2S1IMU6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1827580:DC008 RS29595
gene id: 1827580:DC008_RS29595
uniprot id: A0A2S1ILG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1827580:DC008 RS22610
gene id: 1827580:DC008_RS22610
uniprot id: A0A2S1IHW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1827580:DC008 RS19865
gene id: 1827580:DC008_RS19865
uniprot id: A0A2S1IGH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1827580:DC008 RS05635
gene id: 1827580:DC008_RS05635
uniprot id: A0A2S1I9C5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1827580:DC008 RS16120
gene id: 1827580:DC008_RS16120
uniprot id: A0A2S1IEM0
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

1827580:DC008 RS03130
gene id: 1827580:DC008_RS03130
uniprot id: A0A2S1I8C4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1827580:DC008 RS13045
gene id: 1827580:DC008_RS13045
uniprot id: A0A2S1ID80
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1827580:DC008 RS23525
gene id: 1827580:DC008_RS23525
uniprot id: A0A2S1IIT2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1827580:DC008 RS19770
gene id: 1827580:DC008_RS19770
uniprot id: A0A2S1IGH9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1827580:DC008 RS09130
gene id: 1827580:DC008_RS09130
uniprot id: A0A2S1IB79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1827580:DC008 RS07975
gene id: 1827580:DC008_RS07975
uniprot id: A0A2S1IB68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1827580:DC008 RS08005
gene id: 1827580:DC008_RS08005
uniprot id: A0A2S1IAK3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1827580:DC008 RS08615
gene id: 1827580:DC008_RS08615
uniprot id: A0A2S1IAX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

1827580:DC008 RS24010
gene id: 1827580:DC008_RS24010
uniprot id: A0A2S1IJ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1827580:DC008 RS20760
gene id: 1827580:DC008_RS20760
uniprot id: A0A2S1IGX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1827580:DC008 RS33005
gene id: 1827580:DC008_RS33005
uniprot id: A0A2S1IN49
names: Subcellular Location Annotation
messages: Cytoplasm

1827580:DC008 RS05605
gene id: 1827580:DC008_RS05605
uniprot id: A0A2S1I9B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1827580:DC008 RS05530
gene id: 1827580:DC008_RS05530
uniprot id: A0A2S1I9K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1827580:DC008 RS18730
gene id: 1827580:DC008_RS18730
uniprot id: A0A2S1IFZ9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1827580:DC008 RS19375
gene id: 1827580:DC008_RS19375
uniprot id: A0A2S1IGV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1827580:DC008 RS06715
gene id: 1827580:DC008_RS06715
uniprot id: A0A2S1I9Y1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1827580:DC008 RS20205
gene id: 1827580:DC008_RS20205
uniprot id: A0A2S1IGR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1827580:DC008 RS05040
gene id: 1827580:DC008_RS05040
uniprot id: A0A2S1I944
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1827580:DC008 RS25660
gene id: 1827580:DC008_RS25660
uniprot id: A0A2S1IJF2
names: Similarity
messages: Belongs to the WXG100 family.

1827580:DC008 RS11590
gene id: 1827580:DC008_RS11590
uniprot id: A0A2S1ICD5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1827580:DC008 RS13400
gene id: 1827580:DC008_RS13400
uniprot id: A0A2S1IDI9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1827580:DC008 RS21170
gene id: 1827580:DC008_RS21170
uniprot id: A0A2S1IH54
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1827580:DC008 RS20015
gene id: 1827580:DC008_RS20015
uniprot id: A0A2S1IGI8
names: Similarity
messages: Belongs to the UbiD family.

1827580:DC008 RS07270
gene id: 1827580:DC008_RS07270
uniprot id: A0A2S1IA78
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1827580:DC008 RS32720
gene id: 1827580:DC008_RS32720
uniprot id: A0A2S1IQL5
names: Subcellular Location Annotation
messages: Membrane

1827580:DC008 RS21935
gene id: 1827580:DC008_RS21935
uniprot id: A0A2S1IHH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1827580:DC008 RS20850
gene id: 1827580:DC008_RS20850
uniprot id: A0A2S1IH24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1827580:DC008 RS19400
gene id: 1827580:DC008_RS19400
uniprot id: A0A2S1IG56
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1827580:DC008 RS20735
gene id: 1827580:DC008_RS20735
uniprot id: A0A2S1IGX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1827580:DC008 RS21160
gene id: 1827580:DC008_RS21160
uniprot id: A0A2S1IH35
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1827580:DC008 RS09030
gene id: 1827580:DC008_RS09030
uniprot id: A0A2S1IBC0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1827580:DC008 RS05615
gene id: 1827580:DC008_RS05615
uniprot id: A0A2S1I9H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1827580:DC008 RS04800
gene id: 1827580:DC008_RS04800
uniprot id: A0A2S1I8Y7
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1827580:DC008 RS14335
gene id: 1827580:DC008_RS14335
uniprot id: A0A2S1IDT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1827580:DC008 RS25200
gene id: 1827580:DC008_RS25200
uniprot id: A0A2S1IJ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1827580:DC008 RS22055
gene id: 1827580:DC008_RS22055
uniprot id: A0A2S1IHM8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1827580:DC008 RS04960
gene id: 1827580:DC008_RS04960
uniprot id: A0A2S1I954
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1827580:DC008 RS05390
gene id: 1827580:DC008_RS05390
uniprot id: A0A2S1I978
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1827580:DC008 RS20890
gene id: 1827580:DC008_RS20890
uniprot id: A0A2S1IGZ9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1827580:DC008 RS20820
gene id: 1827580:DC008_RS20820
uniprot id: A0A2S1IGY6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1827580:DC008 RS20885
gene id: 1827580:DC008_RS20885
uniprot id: A0A2S1IGX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1827580:DC008 RS23985
gene id: 1827580:DC008_RS23985
uniprot id: A0A2S1IIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1827580:DC008 RS19170
gene id: 1827580:DC008_RS19170
uniprot id: A0A2S1IG12
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1827580:DC008 RS23980
gene id: 1827580:DC008_RS23980
uniprot id: A0A2S1IIK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1827580:DC008 RS17545
gene id: 1827580:DC008_RS17545
uniprot id: A0A2S1IFB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1827580:DC008 RS23945
gene id: 1827580:DC008_RS23945
uniprot id: A0A2S1III4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1827580:DC008 RS24255
gene id: 1827580:DC008_RS24255
uniprot id: A0A2S1IIQ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1827580:DC008 RS24640
gene id: 1827580:DC008_RS24640
uniprot id: A0A2S1IIV8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1827580:DC008 RS13475
gene id: 1827580:DC008_RS13475
uniprot id: A0A2S1IDB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1827580:DC008 RS19355
gene id: 1827580:DC008_RS19355
uniprot id: A0A2S1IG75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1827580:DC008 RS17455
gene id: 1827580:DC008_RS17455
uniprot id: A0A2S1IFD7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1827580:DC008 RS20710
gene id: 1827580:DC008_RS20710
uniprot id: A0A2S1IGW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1827580:DC008 RS18270
gene id: 1827580:DC008_RS18270
uniprot id: A0A2S1IFL8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1827580:DC008 RS25520
gene id: 1827580:DC008_RS25520
uniprot id: A0A2S1IJH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1827580:DC008 RS34570
gene id: 1827580:DC008_RS34570
uniprot id: A0A2S1INT9
names: Similarity
messages: Belongs to the WXG100 family.

1827580:DC008 RS19595
gene id: 1827580:DC008_RS19595
uniprot id: A0A2S1IGG0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1827580:DC008 RS14170
gene id: 1827580:DC008_RS14170
uniprot id: A0A2S1IDQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1827580:DC008 RS12850
gene id: 1827580:DC008_RS12850
uniprot id: A0A2S1ID04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1827580:DC008 RS20705
gene id: 1827580:DC008_RS20705
uniprot id: A0A2S1IGW2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1827580:DC008 RS06870
gene id: 1827580:DC008_RS06870
uniprot id: A0A2S1IA87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1827580:DC008 RS25295
gene id: 1827580:DC008_RS25295
uniprot id: A0A2S1IQ85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1827580:DC008 RS17940
gene id: 1827580:DC008_RS17940
uniprot id: A0A2S1IFN6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1827580:DC008 RS11275
gene id: 1827580:DC008_RS11275
uniprot id: A0A2S1ICF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1827580:DC008 RS13330
gene id: 1827580:DC008_RS13330
uniprot id: A0A2S1IDD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1827580:DC008 RS09725
gene id: 1827580:DC008_RS09725
uniprot id: A0A2S1IBH1
names: Subcellular Location Annotation
messages: Membrane

1827580:DC008 RS13835
gene id: 1827580:DC008_RS13835
uniprot id: A0A2S1IDJ8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1827580:DC008 RS20800
gene id: 1827580:DC008_RS20800
uniprot id: A0A2S1IH15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1827580:DC008 RS07845
gene id: 1827580:DC008_RS07845
uniprot id: A0A2S1IAI0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1827580:DC008 RS26945
gene id: 1827580:DC008_RS26945
uniprot id: A0A2S1IK19
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1827580:DC008 RS34635
gene id: 1827580:DC008_RS34635
uniprot id: A0A2S1INU9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1827580:DC008 RS06470
gene id: 1827580:DC008_RS06470
uniprot id: A0A2S1I9S8
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1827580:DC008 RS13345
gene id: 1827580:DC008_RS13345
uniprot id: A0A2S1IDA1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1827580:DC008 RS20385
gene id: 1827580:DC008_RS20385
uniprot id: A0A2S1IGR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1827580:DC008 RS11305
gene id: 1827580:DC008_RS11305
uniprot id: A0A2S1ICV1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1827580:DC008 RS07235
gene id: 1827580:DC008_RS07235
uniprot id: A0A2S1IA71
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1827580:DC008 RS24550
gene id: 1827580:DC008_RS24550
uniprot id: A0A2S1IIZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1827580:DC008 RS12305
gene id: 1827580:DC008_RS12305
uniprot id: A0A2S1ICU8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1827580:DC008 RS08605
gene id: 1827580:DC008_RS08605
uniprot id: A0A2S1IAW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1827580:DC008 RS15935
gene id: 1827580:DC008_RS15935
uniprot id: A0A2S1IEQ1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1827580:DC008 RS13010
gene id: 1827580:DC008_RS13010
uniprot id: A0A2S1ID33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1827580:DC008 RS20945
gene id: 1827580:DC008_RS20945
uniprot id: A0A2S1IHL5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1827580:DC008 RS25020
gene id: 1827580:DC008_RS25020
uniprot id: A0A2S1IJ67
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1827580:DC008 RS21375
gene id: 1827580:DC008_RS21375
uniprot id: A0A2S1IH79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1827580:DC008 RS22455
gene id: 1827580:DC008_RS22455
uniprot id: A0A2S1IHT5
names: Similarity
messages: Belongs to the FBPase class 2 family.

1827580:DC008 RS25195
gene id: 1827580:DC008_RS25195
uniprot id: A0A2S1IJ63
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1827580:DC008 RS09155
gene id: 1827580:DC008_RS09155
uniprot id: A0A2S1IB76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1827580:DC008 RS10715
gene id: 1827580:DC008_RS10715
uniprot id: A0A2S1ICK8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1827580:DC008 RS20200
gene id: 1827580:DC008_RS20200
uniprot id: A0A2S1IGP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1827580:DC008 RS18430
gene id: 1827580:DC008_RS18430
uniprot id: A0A2S1IFU8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1827580:DC008 RS14660
gene id: 1827580:DC008_RS14660
uniprot id: A0A2S1IDX7
names: Subcellular Location Annotation
messages: Cytoplasm

1827580:DC008 RS25840
gene id: 1827580:DC008_RS25840
uniprot id: A0A2S1IJI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1827580:DC008 RS29790
gene id: 1827580:DC008_RS29790
uniprot id: A0A2S1ILI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1827580:DC008 RS15765
gene id: 1827580:DC008_RS15765
uniprot id: A0A2S1IEH4
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1827580:DC008 RS20860
gene id: 1827580:DC008_RS20860
uniprot id: A0A2S1IGY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1827580:DC008 RS20995
gene id: 1827580:DC008_RS20995
uniprot id: A0A2S1IH00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1827580:DC008 RS00045
gene id: 1827580:DC008_RS00045
uniprot id: A0A2S1INU9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1827580:DC008 RS21130
gene id: 1827580:DC008_RS21130
uniprot id: A0A2S1IHP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1827580:DC008 RS21105
gene id: 1827580:DC008_RS21105
uniprot id: A0A2S1IH39
names: Similarity
messages: Belongs to the YciI family.

1827580:DC008 RS24720
gene id: 1827580:DC008_RS24720
uniprot id: A0A2S1IJ08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1827580:DC008 RS08765
gene id: 1827580:DC008_RS08765
uniprot id: A0A2S1IAZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1827580:DC008 RS10575
gene id: 1827580:DC008_RS10575
uniprot id: A0A2S1IBX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1827580:DC008 RS25290
gene id: 1827580:DC008_RS25290
uniprot id: A0A2S1IJB7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1827580:DC008 RS20815
gene id: 1827580:DC008_RS20815
uniprot id: A0A2S1IGY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1827580:DC008 RS03990
gene id: 1827580:DC008_RS03990
uniprot id: A0A2S1I8G9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1827580:DC008 RS19590
gene id: 1827580:DC008_RS19590
uniprot id: A0A2S1IGF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

1827580:DC008 RS06290
gene id: 1827580:DC008_RS06290
uniprot id: A0A2S1I9P7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1827580:DC008 RS13315
gene id: 1827580:DC008_RS13315
uniprot id: A0A2S1IDX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1827580:DC008 RS16485
gene id: 1827580:DC008_RS16485
uniprot id: A0A2S1IPU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1827580:DC008 RS24870
gene id: 1827580:DC008_RS24870
uniprot id: A0A2S1IJ56
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1827580:DC008 RS28545
gene id: 1827580:DC008_RS28545
uniprot id: A0A2S1IKV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

1827580:DC008 RS20920
gene id: 1827580:DC008_RS20920
uniprot id: A0A2S1IGZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1827580:DC008 RS21060
gene id: 1827580:DC008_RS21060
uniprot id: A0A2S1IH30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1827580:DC008 RS05460
gene id: 1827580:DC008_RS05460
uniprot id: A0A2S1I9A1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1827580:DC008 RS31925
gene id: 1827580:DC008_RS31925
uniprot id: A0A2S1IMI0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1827580:DC008 RS21810
gene id: 1827580:DC008_RS21810
uniprot id: A0A2S1IHE2
names: Subcellular Location Annotation
messages: Membrane

1827580:DC008 RS27020
gene id: 1827580:DC008_RS27020
uniprot id: A0A2S1IK48
names: Subcellular Location Annotation
messages: Membrane

1827580:DC008 RS14730
gene id: 1827580:DC008_RS14730
uniprot id: A0A2S1IDX2
names: Subcellular Location Annotation
messages: Membrane

1827580:DC008 RS01860
gene id: 1827580:DC008_RS01860
uniprot id: A0A2S1I7D5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1827580:DC008 RS31640
gene id: 1827580:DC008_RS31640
uniprot id: A0A2S1IME4
names: Similarity
messages: Belongs to the CsoR family.

1827580:DC008 RS25215
gene id: 1827580:DC008_RS25215
uniprot id: A0A2S1IJ69
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1827580:DC008 RS20720
gene id: 1827580:DC008_RS20720
uniprot id: A0A2S1IGW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1827580:DC008 RS17410
gene id: 1827580:DC008_RS17410
uniprot id: A0A2S1IFF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1827580:DC008 RS05260
gene id: 1827580:DC008_RS05260
uniprot id: A0A2S1I967
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1827580:DC008 RS05400
gene id: 1827580:DC008_RS05400
uniprot id: A0A2S1I9D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1827580:DC008 RS20755
gene id: 1827580:DC008_RS20755
uniprot id: A0A2S1IGW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1827580:DC008 RS07555
gene id: 1827580:DC008_RS07555
uniprot id: A0A2S1IAC9
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1827580:DC008 RS11280
gene id: 1827580:DC008_RS11280
uniprot id: A0A2S1IC93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.