1811193:A0O21 RS10385
gene id: 1811193:A0O21_RS10385
uniprot id: A0A172QAB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1811193:A0O21 RS05510
gene id: 1811193:A0O21_RS05510
uniprot id: A0A172Q7Z7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1811193:A0O21 RS07400
gene id: 1811193:A0O21_RS07400
uniprot id: A0A172Q8S4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1811193:A0O21 RS10315
gene id: 1811193:A0O21_RS10315
uniprot id: A0A172QA70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1811193:A0O21 RS04045
gene id: 1811193:A0O21_RS04045
uniprot id: A0A172Q763
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1811193:A0O21 RS02410
gene id: 1811193:A0O21_RS02410
uniprot id: A0A172Q643
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS09935
gene id: 1811193:A0O21_RS09935
uniprot id: A0A172Q9Y4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1811193:A0O21 RS07025
gene id: 1811193:A0O21_RS07025
uniprot id: A0A172Q8M0
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

1811193:A0O21 RS07480
gene id: 1811193:A0O21_RS07480
uniprot id: A0A172Q8W5
names: Similarity
messages: Belongs to the fabD family.

1811193:A0O21 RS04215
gene id: 1811193:A0O21_RS04215
uniprot id: A0A172Q789
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1811193:A0O21 RS03775
gene id: 1811193:A0O21_RS03775
uniprot id: A0A172Q6Y5
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1811193:A0O21 RS00545
gene id: 1811193:A0O21_RS00545
uniprot id: A0A172Q589
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1811193:A0O21 RS02415
gene id: 1811193:A0O21_RS02415
uniprot id: A0A172Q669
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1811193:A0O21 RS01865
gene id: 1811193:A0O21_RS01865
uniprot id: A0A172Q5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1811193:A0O21 RS06085
gene id: 1811193:A0O21_RS06085
uniprot id: A0A172Q853
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1811193:A0O21 RS04330
gene id: 1811193:A0O21_RS04330
uniprot id: A0A172Q787
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1811193:A0O21 RS03630
gene id: 1811193:A0O21_RS03630
uniprot id: A0A172Q6W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1811193:A0O21 RS08470
gene id: 1811193:A0O21_RS08470
uniprot id: A0A172Q9C3
names: Similarity
messages: Belongs to the UPF0177 family.

1811193:A0O21 RS08515
gene id: 1811193:A0O21_RS08515
uniprot id: A0A172Q9C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1811193:A0O21 RS08985
gene id: 1811193:A0O21_RS08985
uniprot id: A0A172Q9I3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1811193:A0O21 RS05190
gene id: 1811193:A0O21_RS05190
uniprot id: A0A172Q7L3
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1811193:A0O21 RS01385
gene id: 1811193:A0O21_RS01385
uniprot id: A0A172Q5M9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1811193:A0O21 RS06230
gene id: 1811193:A0O21_RS06230
uniprot id: A0A172Q863
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1811193:A0O21 RS09065
gene id: 1811193:A0O21_RS09065
uniprot id: A0A172Q9H6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1811193:A0O21 RS00560
gene id: 1811193:A0O21_RS00560
uniprot id: A0A172Q575
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1811193:A0O21 RS03570
gene id: 1811193:A0O21_RS03570
uniprot id: A0A172Q6U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1811193:A0O21 RS03540
gene id: 1811193:A0O21_RS03540
uniprot id: A0A172Q6Y8
names: Similarity
messages: Belongs to the peptidase C59 family.

1811193:A0O21 RS09510
gene id: 1811193:A0O21_RS09510
uniprot id: A0A172Q9Z0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1811193:A0O21 RS03095
gene id: 1811193:A0O21_RS03095
uniprot id: A0A172Q6L1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1811193:A0O21 RS07255
gene id: 1811193:A0O21_RS07255
uniprot id: A0A172Q8M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MapZ family.
messages: Cell membrane
messages: Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning.
messages: Interacts with FtsZ.

1811193:A0O21 RS09330
gene id: 1811193:A0O21_RS09330
uniprot id: A0A172Q9S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1811193:A0O21 RS09905
gene id: 1811193:A0O21_RS09905
uniprot id: A0A172QA23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1811193:A0O21 RS08075
gene id: 1811193:A0O21_RS08075
uniprot id: A0A172QAM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1811193:A0O21 RS07605
gene id: 1811193:A0O21_RS07605
uniprot id: A0A172Q8R8
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily.
messages: Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.

1811193:A0O21 RS08010
gene id: 1811193:A0O21_RS08010
uniprot id: A0A172Q942
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1811193:A0O21 RS10110
gene id: 1811193:A0O21_RS10110
uniprot id: A0A172QA49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1811193:A0O21 RS10495
gene id: 1811193:A0O21_RS10495
uniprot id: A0A172QAB0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS08715
gene id: 1811193:A0O21_RS08715
uniprot id: A0A172Q9I1
names: Similarity
messages: Belongs to the aldose epimerase family.

1811193:A0O21 RS04805
gene id: 1811193:A0O21_RS04805
uniprot id: A0A172Q7D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

1811193:A0O21 RS06365
gene id: 1811193:A0O21_RS06365
uniprot id: A0A172Q8C0
names: Similarity
messages: Belongs to the UPF0177 family.

1811193:A0O21 RS06410
gene id: 1811193:A0O21_RS06410
uniprot id: A0A172Q8A8
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS03670
gene id: 1811193:A0O21_RS03670
uniprot id: A0A172Q6S7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1811193:A0O21 RS03120
gene id: 1811193:A0O21_RS03120
uniprot id: A0A172Q6K1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1811193:A0O21 RS10295
gene id: 1811193:A0O21_RS10295
uniprot id: A0A172QA82
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1811193:A0O21 RS09680
gene id: 1811193:A0O21_RS09680
uniprot id: A0A172Q9W0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1811193:A0O21 RS03750
gene id: 1811193:A0O21_RS03750
uniprot id: A0A172Q726
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS10490
gene id: 1811193:A0O21_RS10490
uniprot id: A0A172QA76
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1811193:A0O21 RS10170
gene id: 1811193:A0O21_RS10170
uniprot id: A0A172QA09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1811193:A0O21 RS07300
gene id: 1811193:A0O21_RS07300
uniprot id: A0A172Q8S9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1811193:A0O21 RS03560
gene id: 1811193:A0O21_RS03560
uniprot id: A0A172Q6S9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS03785
gene id: 1811193:A0O21_RS03785
uniprot id: A0A172Q6Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS05925
gene id: 1811193:A0O21_RS05925
uniprot id: A0A172Q803
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1811193:A0O21 RS09580
gene id: 1811193:A0O21_RS09580
uniprot id: A0A172Q9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1811193:A0O21 RS04480
gene id: 1811193:A0O21_RS04480
uniprot id: A0A172Q7D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1811193:A0O21 RS06785
gene id: 1811193:A0O21_RS06785
uniprot id: A0A172Q8I2
names: Similarity
messages: Belongs to the Dps family.

1811193:A0O21 RS03340
gene id: 1811193:A0O21_RS03340
uniprot id: A0A172Q6T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1811193:A0O21 RS07090
gene id: 1811193:A0O21_RS07090
uniprot id: A0A172Q8P9
names: Similarity
messages: Belongs to the UPF0374 family.

1811193:A0O21 RS04035
gene id: 1811193:A0O21_RS04035
uniprot id: A0A172QAH8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1811193:A0O21 RS03025
gene id: 1811193:A0O21_RS03025
uniprot id: A0A172Q6I0
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS02730
gene id: 1811193:A0O21_RS02730
uniprot id: A0A172Q691
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1811193:A0O21 RS05625
gene id: 1811193:A0O21_RS05625
uniprot id: A0A172Q7S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1811193:A0O21 RS05905
gene id: 1811193:A0O21_RS05905
uniprot id: A0A172Q808
names: Similarity
messages: Belongs to the RecJ family.

1811193:A0O21 RS00520
gene id: 1811193:A0O21_RS00520
uniprot id: A0A172Q5B6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1811193:A0O21 RS07000
gene id: 1811193:A0O21_RS07000
uniprot id: A0A172Q8M5
names: Subcellular Location Annotation
messages: cell wall

1811193:A0O21 RS03805
gene id: 1811193:A0O21_RS03805
uniprot id: A0A172Q735
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1811193:A0O21 RS03645
gene id: 1811193:A0O21_RS03645
uniprot id: A0A172Q6U2
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS10395
gene id: 1811193:A0O21_RS10395
uniprot id: A0A172QA90
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1811193:A0O21 RS01180
gene id: 1811193:A0O21_RS01180
uniprot id: A0A172Q5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1811193:A0O21 RS07650
gene id: 1811193:A0O21_RS07650
uniprot id: A0A172Q8V1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1811193:A0O21 RS03155
gene id: 1811193:A0O21_RS03155
uniprot id: A0A172Q6H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1811193:A0O21 RS10135
gene id: 1811193:A0O21_RS10135
uniprot id: A0A172QA53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1811193:A0O21 RS10360
gene id: 1811193:A0O21_RS10360
uniprot id: A0A172QA65
names: Similarity
messages: Belongs to the GSP E family.

1811193:A0O21 RS06255
gene id: 1811193:A0O21_RS06255
uniprot id: A0A172Q884
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

1811193:A0O21 RS01515
gene id: 1811193:A0O21_RS01515
uniprot id: A0A172Q5P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1811193:A0O21 RS08770
gene id: 1811193:A0O21_RS08770
uniprot id: A0A172Q9E7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1811193:A0O21 RS03600
gene id: 1811193:A0O21_RS03600
uniprot id: A0A172Q6U0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1811193:A0O21 RS04355
gene id: 1811193:A0O21_RS04355
uniprot id: A0A172Q7D4
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1811193:A0O21 RS01830
gene id: 1811193:A0O21_RS01830
uniprot id: A0A172Q5U5
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS00840
gene id: 1811193:A0O21_RS00840
uniprot id: A0A172Q5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1811193:A0O21 RS03700
gene id: 1811193:A0O21_RS03700
uniprot id: A0A172Q714
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS00815
gene id: 1811193:A0O21_RS00815
uniprot id: A0A172Q5C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1811193:A0O21 RS08930
gene id: 1811193:A0O21_RS08930
uniprot id: A0A172Q9D5
names: Similarity
messages: Belongs to the peptidase M13 family.

1811193:A0O21 RS08645
gene id: 1811193:A0O21_RS08645
uniprot id: A0A172Q9C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1811193:A0O21 RS04505
gene id: 1811193:A0O21_RS04505
uniprot id: A0A172Q7E2
names: Similarity
messages: Belongs to the DprA/Smf family.

1811193:A0O21 RS09550
gene id: 1811193:A0O21_RS09550
uniprot id: A0A172Q9N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS02175
gene id: 1811193:A0O21_RS02175
uniprot id: A0A172Q607
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1811193:A0O21 RS01935
gene id: 1811193:A0O21_RS01935
uniprot id: A0A172Q5W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GtfB family.
messages: Cell membrane
messages: Forms a heterotetramer with 2 subunits each of GtfA and GtfB. Part of the accessory SecA2/SecY2 protein translocation apparatus.
messages: Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.

1811193:A0O21 RS01975
gene id: 1811193:A0O21_RS01975
uniprot id: A0A172Q610
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1811193:A0O21 RS05685
gene id: 1811193:A0O21_RS05685
uniprot id: A0A172Q7T0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1811193:A0O21 RS06635
gene id: 1811193:A0O21_RS06635
uniprot id: A0A172QAK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1811193:A0O21 RS00290
gene id: 1811193:A0O21_RS00290
uniprot id: A0A172Q536
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1811193:A0O21 RS09875
gene id: 1811193:A0O21_RS09875
uniprot id: A0A172Q9S4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1811193:A0O21 RS02795
gene id: 1811193:A0O21_RS02795
uniprot id: A0A172Q6D9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1811193:A0O21 RS00625
gene id: 1811193:A0O21_RS00625
uniprot id: A0A172Q5B0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1811193:A0O21 RS04600
gene id: 1811193:A0O21_RS04600
uniprot id: A0A172Q7D2
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS06645
gene id: 1811193:A0O21_RS06645
uniprot id: A0A172Q8K9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS05310
gene id: 1811193:A0O21_RS05310
uniprot id: A0A172Q7U1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1811193:A0O21 RS06500
gene id: 1811193:A0O21_RS06500
uniprot id: A0A172Q8D0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1811193:A0O21 RS07050
gene id: 1811193:A0O21_RS07050
uniprot id: A0A172Q8S3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS09060
gene id: 1811193:A0O21_RS09060
uniprot id: A0A172Q9N2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1811193:A0O21 RS10075
gene id: 1811193:A0O21_RS10075
uniprot id: A0A172QA24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1811193:A0O21 RS01660
gene id: 1811193:A0O21_RS01660
uniprot id: A0A172Q5X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1811193:A0O21 RS07785
gene id: 1811193:A0O21_RS07785
uniprot id: A0A172Q8U0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1811193:A0O21 RS06625
gene id: 1811193:A0O21_RS06625
uniprot id: A0A172Q8G7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1811193:A0O21 RS08070
gene id: 1811193:A0O21_RS08070
uniprot id: A0A172Q933
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1811193:A0O21 RS00060
gene id: 1811193:A0O21_RS00060
uniprot id: A0A172Q517
names: Similarity
messages: Belongs to the WXG100 family.

1811193:A0O21 RS02425
gene id: 1811193:A0O21_RS02425
uniprot id: A0A172Q672
names: Similarity
messages: Belongs to the nitroreductase family.

1811193:A0O21 RS05480
gene id: 1811193:A0O21_RS05480
uniprot id: A0A172Q7U3
names: Similarity
messages: Belongs to the UPF0177 family.

1811193:A0O21 RS05215
gene id: 1811193:A0O21_RS05215
uniprot id: A0A172Q7K0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1811193:A0O21 RS08790
gene id: 1811193:A0O21_RS08790
uniprot id: A0A172Q9G5
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1811193:A0O21 RS00125
gene id: 1811193:A0O21_RS00125
uniprot id: A0A172Q517
names: Similarity
messages: Belongs to the WXG100 family.

1811193:A0O21 RS03190
gene id: 1811193:A0O21_RS03190
uniprot id: A0A172Q6M1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1811193:A0O21 RS07280
gene id: 1811193:A0O21_RS07280
uniprot id: A0A172Q8R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1811193:A0O21 RS06620
gene id: 1811193:A0O21_RS06620
uniprot id: A0A172Q8E8
names: Similarity
messages: Belongs to the TlyA family.

1811193:A0O21 RS02930
gene id: 1811193:A0O21_RS02930
uniprot id: A0A172Q6G7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1811193:A0O21 RS09500
gene id: 1811193:A0O21_RS09500
uniprot id: A0A172Q9M3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1811193:A0O21 RS03395
gene id: 1811193:A0O21_RS03395
uniprot id: A0A172QAG7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1811193:A0O21 RS00920
gene id: 1811193:A0O21_RS00920
uniprot id: A0A172Q5E3
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1811193:A0O21 RS01960
gene id: 1811193:A0O21_RS01960
uniprot id: A0A172Q601
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1811193:A0O21 RS05800
gene id: 1811193:A0O21_RS05800
uniprot id: A0A172Q7Y4
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS06445
gene id: 1811193:A0O21_RS06445
uniprot id: A0A172Q8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1811193:A0O21 RS01530
gene id: 1811193:A0O21_RS01530
uniprot id: A0A172Q5V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS04775
gene id: 1811193:A0O21_RS04775
uniprot id: A0A172Q7F9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1811193:A0O21 RS05135
gene id: 1811193:A0O21_RS05135
uniprot id: A0A172Q7S8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1811193:A0O21 RS01835
gene id: 1811193:A0O21_RS01835
uniprot id: A0A172Q5X5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1811193:A0O21 RS01680
gene id: 1811193:A0O21_RS01680
uniprot id: A0A172Q5V9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS02015
gene id: 1811193:A0O21_RS02015
uniprot id: A0A172Q611
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS01275
gene id: 1811193:A0O21_RS01275
uniprot id: A0A172Q5L3
names: Similarity
names: Subunit
messages: Belongs to the LacAB/RpiB family.
messages: Heteromultimeric protein consisting of LacA and LacB.

1811193:A0O21 RS06345
gene id: 1811193:A0O21_RS06345
uniprot id: A0A172Q8A0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1811193:A0O21 RS09630
gene id: 1811193:A0O21_RS09630
uniprot id: A0A172Q9U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS03390
gene id: 1811193:A0O21_RS03390
uniprot id: A0A172Q6U3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1811193:A0O21 RS09050
gene id: 1811193:A0O21_RS09050
uniprot id: A0A172Q9J9
names: Similarity
messages: In the C-terminal section; belongs to the NRP synthetase family.

1811193:A0O21 RS07405
gene id: 1811193:A0O21_RS07405
uniprot id: A0A172Q8U3
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS00845
gene id: 1811193:A0O21_RS00845
uniprot id: A0A172Q5H2
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS01130
gene id: 1811193:A0O21_RS01130
uniprot id: A0A172Q5I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1811193:A0O21 RS10145
gene id: 1811193:A0O21_RS10145
uniprot id: A0A172QA27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1811193:A0O21 RS09995
gene id: 1811193:A0O21_RS09995
uniprot id: A0A172Q9Z6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1811193:A0O21 RS09340
gene id: 1811193:A0O21_RS09340
uniprot id: A0A172Q9P7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS05220
gene id: 1811193:A0O21_RS05220
uniprot id: A0A172Q7P3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1811193:A0O21 RS03650
gene id: 1811193:A0O21_RS03650
uniprot id: A0A172Q703
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS03755
gene id: 1811193:A0O21_RS03755
uniprot id: A0A172Q6X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS06350
gene id: 1811193:A0O21_RS06350
uniprot id: A0A172Q858
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1811193:A0O21 RS08300
gene id: 1811193:A0O21_RS08300
uniprot id: A0A172Q989
names: Function
names: Similarity
names: Subunit
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.

1811193:A0O21 RS09595
gene id: 1811193:A0O21_RS09595
uniprot id: A0A172Q9X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1811193:A0O21 RS02040
gene id: 1811193:A0O21_RS02040
uniprot id: A0A172Q617
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1811193:A0O21 RS02065
gene id: 1811193:A0O21_RS02065
uniprot id: A0A172Q640
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1811193:A0O21 RS09470
gene id: 1811193:A0O21_RS09470
uniprot id: A0A172Q9V7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1811193:A0O21 RS01645
gene id: 1811193:A0O21_RS01645
uniprot id: A0A172Q5R8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1811193:A0O21 RS04400
gene id: 1811193:A0O21_RS04400
uniprot id: A0A172Q7C3
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS06095
gene id: 1811193:A0O21_RS06095
uniprot id: A0A172QAK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1811193:A0O21 RS01925
gene id: 1811193:A0O21_RS01925
uniprot id: A0A172QAB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1811193:A0O21 RS04190
gene id: 1811193:A0O21_RS04190
uniprot id: A0A172Q706
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1811193:A0O21 RS08415
gene id: 1811193:A0O21_RS08415
uniprot id: A0A172Q944
names: Similarity
messages: Belongs to the UPF0177 family.

1811193:A0O21 RS01380
gene id: 1811193:A0O21_RS01380
uniprot id: A0A172Q5Q0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1811193:A0O21 RS01425
gene id: 1811193:A0O21_RS01425
uniprot id: A0A172Q5R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1811193:A0O21 RS04385
gene id: 1811193:A0O21_RS04385
uniprot id: A0A172Q753
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1811193:A0O21 RS02200
gene id: 1811193:A0O21_RS02200
uniprot id: A0A172QAB3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS03870
gene id: 1811193:A0O21_RS03870
uniprot id: A0A172Q6Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1811193:A0O21 RS04570
gene id: 1811193:A0O21_RS04570
uniprot id: A0A172Q7B6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1811193:A0O21 RS03080
gene id: 1811193:A0O21_RS03080
uniprot id: A0A172Q6J0
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS05375
gene id: 1811193:A0O21_RS05375
uniprot id: A0A172Q7N3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1811193:A0O21 RS07085
gene id: 1811193:A0O21_RS07085
uniprot id: A0A172Q8M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1811193:A0O21 RS05070
gene id: 1811193:A0O21_RS05070
uniprot id: A0A172Q7H0
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS03865
gene id: 1811193:A0O21_RS03865
uniprot id: A0A172Q731
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1811193:A0O21 RS01930
gene id: 1811193:A0O21_RS01930
uniprot id: A0A172QAB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Forms a heterotetramer with 2 subunits each of GtfA and GtfB. Part of the accessory SecA2/SecY2 protein translocation apparatus.
messages: Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in the substrate protein. Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon.

1811193:A0O21 RS04560
gene id: 1811193:A0O21_RS04560
uniprot id: A0A172Q7F2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1811193:A0O21 RS01095
gene id: 1811193:A0O21_RS01095
uniprot id: A0A172Q5J6
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1811193:A0O21 RS04510
gene id: 1811193:A0O21_RS04510
uniprot id: A0A172Q771
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1811193:A0O21 RS04720
gene id: 1811193:A0O21_RS04720
uniprot id: A0A172QAE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1811193:A0O21 RS05645
gene id: 1811193:A0O21_RS05645
uniprot id: A0A172Q800
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1811193:A0O21 RS01795
gene id: 1811193:A0O21_RS01795
uniprot id: A0A172Q5X7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1811193:A0O21 RS04650
gene id: 1811193:A0O21_RS04650
uniprot id: A0A172Q7E3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1811193:A0O21 RS05530
gene id: 1811193:A0O21_RS05530
uniprot id: A0A172Q7U9
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS07495
gene id: 1811193:A0O21_RS07495
uniprot id: A0A172Q8U2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1811193:A0O21 RS10130
gene id: 1811193:A0O21_RS10130
uniprot id: A0A172QA37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1811193:A0O21 RS01510
gene id: 1811193:A0O21_RS01510
uniprot id: A0A172Q5X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1811193:A0O21 RS07770
gene id: 1811193:A0O21_RS07770
uniprot id: A0A172Q8X5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1811193:A0O21 RS09000
gene id: 1811193:A0O21_RS09000
uniprot id: A0A172Q9M9
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS06875
gene id: 1811193:A0O21_RS06875
uniprot id: A0A172Q8K3
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS04515
gene id: 1811193:A0O21_RS04515
uniprot id: A0A172Q7A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1811193:A0O21 RS00615
gene id: 1811193:A0O21_RS00615
uniprot id: A0A172Q5A8
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1811193:A0O21 RS06360
gene id: 1811193:A0O21_RS06360
uniprot id: A0A172Q8A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1811193:A0O21 RS04985
gene id: 1811193:A0O21_RS04985
uniprot id: A0A172Q7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS01590
gene id: 1811193:A0O21_RS01590
uniprot id: A0A172QA96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

1811193:A0O21 RS07825
gene id: 1811193:A0O21_RS07825
uniprot id: A0A172Q8Y5
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS02820
gene id: 1811193:A0O21_RS02820
uniprot id: A0A172QAG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1811193:A0O21 RS09175
gene id: 1811193:A0O21_RS09175
uniprot id: A0A172Q9J6
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1811193:A0O21 RS03550
gene id: 1811193:A0O21_RS03550
uniprot id: A0A172QAC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS08830
gene id: 1811193:A0O21_RS08830
uniprot id: A0A172Q9F7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1811193:A0O21 RS01715
gene id: 1811193:A0O21_RS01715
uniprot id: A0A172Q5S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1811193:A0O21 RS01825
gene id: 1811193:A0O21_RS01825
uniprot id: A0A172Q627
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS03975
gene id: 1811193:A0O21_RS03975
uniprot id: A0A172Q765
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1811193:A0O21 RS09370
gene id: 1811193:A0O21_RS09370
uniprot id: A0A172Q9R3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1811193:A0O21 RS08940
gene id: 1811193:A0O21_RS08940
uniprot id: A0A172Q9P1
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS01980
gene id: 1811193:A0O21_RS01980
uniprot id: A0A172Q5Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1811193:A0O21 RS05365
gene id: 1811193:A0O21_RS05365
uniprot id: A0A172Q7V3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1811193:A0O21 RS09645
gene id: 1811193:A0O21_RS09645
uniprot id: A0A172Q9T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1811193:A0O21 RS08035
gene id: 1811193:A0O21_RS08035
uniprot id: A0A172Q8X8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1811193:A0O21 RS02590
gene id: 1811193:A0O21_RS02590
uniprot id: A0A172Q6A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS06900
gene id: 1811193:A0O21_RS06900
uniprot id: A0A172Q8F0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1811193:A0O21 RS07995
gene id: 1811193:A0O21_RS07995
uniprot id: A0A172Q975
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1811193:A0O21 RS01690
gene id: 1811193:A0O21_RS01690
uniprot id: A0A172Q5V1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1811193:A0O21 RS07330
gene id: 1811193:A0O21_RS07330
uniprot id: A0A172Q8S6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1811193:A0O21 RS07340
gene id: 1811193:A0O21_RS07340
uniprot id: A0A172Q8M9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1811193:A0O21 RS01920
gene id: 1811193:A0O21_RS01920
uniprot id: A0A172Q5Z5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1811193:A0O21 RS01005
gene id: 1811193:A0O21_RS01005
uniprot id: A0A172Q5I4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS02525
gene id: 1811193:A0O21_RS02525
uniprot id: A0A172Q680
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS01955
gene id: 1811193:A0O21_RS01955
uniprot id: A0A172Q619
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1811193:A0O21 RS04990
gene id: 1811193:A0O21_RS04990
uniprot id: A0A172Q7L8
names: Similarity
messages: Belongs to the pyruvate kinase family.

1811193:A0O21 RS02045
gene id: 1811193:A0O21_RS02045
uniprot id: A0A172Q5Y5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS04315
gene id: 1811193:A0O21_RS04315
uniprot id: A0A172Q7A9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1811193:A0O21 RS10020
gene id: 1811193:A0O21_RS10020
uniprot id: A0A172QA16
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1811193:A0O21 RS00785
gene id: 1811193:A0O21_RS00785
uniprot id: A0A172QAC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1811193:A0O21 RS07680
gene id: 1811193:A0O21_RS07680
uniprot id: A0A172Q8Y3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1811193:A0O21 RS06050
gene id: 1811193:A0O21_RS06050
uniprot id: A0A172Q823
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1811193:A0O21 RS10140
gene id: 1811193:A0O21_RS10140
uniprot id: A0A172Q9X4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1811193:A0O21 RS05230
gene id: 1811193:A0O21_RS05230
uniprot id: A0A172Q7S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1811193:A0O21 RS08535
gene id: 1811193:A0O21_RS08535
uniprot id: A0A172Q9H2
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS00485
gene id: 1811193:A0O21_RS00485
uniprot id: A0A172Q580
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1811193:A0O21 RS00305
gene id: 1811193:A0O21_RS00305
uniprot id: A0A172Q552
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS08420
gene id: 1811193:A0O21_RS08420
uniprot id: A0A172Q979
names: Similarity
messages: Belongs to the UPF0177 family.

1811193:A0O21 RS04465
gene id: 1811193:A0O21_RS04465
uniprot id: A0A172Q795
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1811193:A0O21 RS04930
gene id: 1811193:A0O21_RS04930
uniprot id: A0A172Q7K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS05555
gene id: 1811193:A0O21_RS05555
uniprot id: A0A172Q7R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1811193:A0O21 RS04350
gene id: 1811193:A0O21_RS04350
uniprot id: A0A172Q777
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1811193:A0O21 RS07895
gene id: 1811193:A0O21_RS07895
uniprot id: A0A172Q913
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1811193:A0O21 RS01685
gene id: 1811193:A0O21_RS01685
uniprot id: A0A172Q5T3
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS04625
gene id: 1811193:A0O21_RS04625
uniprot id: A0A172Q7I2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1811193:A0O21 RS02350
gene id: 1811193:A0O21_RS02350
uniprot id: A0A172Q639
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS07270
gene id: 1811193:A0O21_RS07270
uniprot id: A0A172Q8N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

1811193:A0O21 RS03955
gene id: 1811193:A0O21_RS03955
uniprot id: A0A172Q724
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1811193:A0O21 RS03980
gene id: 1811193:A0O21_RS03980
uniprot id: A0A172Q710
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1811193:A0O21 RS09850
gene id: 1811193:A0O21_RS09850
uniprot id: A0A172QA12
names: Similarity
messages: Belongs to the UPF0177 family.

1811193:A0O21 RS09635
gene id: 1811193:A0O21_RS09635
uniprot id: A0A172Q9Y3
names: Similarity
messages: Belongs to the ParB family.

1811193:A0O21 RS06730
gene id: 1811193:A0O21_RS06730
uniprot id: A0A172Q8F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1811193:A0O21 RS07760
gene id: 1811193:A0O21_RS07760
uniprot id: A0A172Q8Z9
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS10155
gene id: 1811193:A0O21_RS10155
uniprot id: A0A172QA28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1811193:A0O21 RS07900
gene id: 1811193:A0O21_RS07900
uniprot id: A0A172Q915
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1811193:A0O21 RS03360
gene id: 1811193:A0O21_RS03360
uniprot id: A0A172Q6R1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1811193:A0O21 RS06070
gene id: 1811193:A0O21_RS06070
uniprot id: A0A172Q849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

1811193:A0O21 RS02300
gene id: 1811193:A0O21_RS02300
uniprot id: A0A172Q650
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1811193:A0O21 RS06055
gene id: 1811193:A0O21_RS06055
uniprot id: A0A172Q894
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1811193:A0O21 RS00315
gene id: 1811193:A0O21_RS00315
uniprot id: A0A172Q555
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1811193:A0O21 RS00995
gene id: 1811193:A0O21_RS00995
uniprot id: A0A172Q5H7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1811193:A0O21 RS06960
gene id: 1811193:A0O21_RS06960
uniprot id: A0A172Q8G1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1811193:A0O21 RS09725
gene id: 1811193:A0O21_RS09725
uniprot id: A0A172QA30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1811193:A0O21 RS07800
gene id: 1811193:A0O21_RS07800
uniprot id: A0A172Q8Y2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1811193:A0O21 RS01305
gene id: 1811193:A0O21_RS01305
uniprot id: A0A172Q5R0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1811193:A0O21 RS00760
gene id: 1811193:A0O21_RS00760
uniprot id: A0A172Q5C1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1811193:A0O21 RS08540
gene id: 1811193:A0O21_RS08540
uniprot id: A0A172Q9A7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1811193:A0O21 RS00950
gene id: 1811193:A0O21_RS00950
uniprot id: A0A172Q5J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

1811193:A0O21 RS02990
gene id: 1811193:A0O21_RS02990
uniprot id: A0A172Q6M5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1811193:A0O21 RS01280
gene id: 1811193:A0O21_RS01280
uniprot id: A0A172Q5M6
names: Similarity
names: Subunit
messages: Belongs to the LacAB/RpiB family.
messages: Heteromultimeric protein consisting of LacA and LacB.

1811193:A0O21 RS01035
gene id: 1811193:A0O21_RS01035
uniprot id: A0A172Q5N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1811193:A0O21 RS09270
gene id: 1811193:A0O21_RS09270
uniprot id: A0A172Q9P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1811193:A0O21 RS09160
gene id: 1811193:A0O21_RS09160
uniprot id: A0A172Q9Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1811193:A0O21 RS04305
gene id: 1811193:A0O21_RS04305
uniprot id: A0A172Q7C5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1811193:A0O21 RS04790
gene id: 1811193:A0O21_RS04790
uniprot id: A0A172Q7G9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS10005
gene id: 1811193:A0O21_RS10005
uniprot id: A0A172QA42
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1811193:A0O21 RS09925
gene id: 1811193:A0O21_RS09925
uniprot id: A0A172QA13
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1811193:A0O21 RS09265
gene id: 1811193:A0O21_RS09265
uniprot id: A0A172Q9P4
names: Similarity
messages: Belongs to the UPF0473 family.

1811193:A0O21 RS02470
gene id: 1811193:A0O21_RS02470
uniprot id: A0A172Q677
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1811193:A0O21 RS00425
gene id: 1811193:A0O21_RS00425
uniprot id: A0A172Q566
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS03210
gene id: 1811193:A0O21_RS03210
uniprot id: A0A172Q6L3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1811193:A0O21 RS08580
gene id: 1811193:A0O21_RS08580
uniprot id: A0A172Q9A9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1811193:A0O21 RS09715
gene id: 1811193:A0O21_RS09715
uniprot id: A0A172Q9R2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1811193:A0O21 RS04085
gene id: 1811193:A0O21_RS04085
uniprot id: A0A172Q728
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS01945
gene id: 1811193:A0O21_RS01945
uniprot id: A0A172Q5W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1811193:A0O21 RS04955
gene id: 1811193:A0O21_RS04955
uniprot id: A0A172Q7I4
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

1811193:A0O21 RS08180
gene id: 1811193:A0O21_RS08180
uniprot id: A0A172Q918
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1811193:A0O21 RS01135
gene id: 1811193:A0O21_RS01135
uniprot id: A0A172Q5Q2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS10180
gene id: 1811193:A0O21_RS10180
uniprot id: A0A172QA47
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1811193:A0O21 RS00475
gene id: 1811193:A0O21_RS00475
uniprot id: A0A172Q577
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS09665
gene id: 1811193:A0O21_RS09665
uniprot id: A0A172Q9Q5
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS04140
gene id: 1811193:A0O21_RS04140
uniprot id: A0A172Q794
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1811193:A0O21 RS04910
gene id: 1811193:A0O21_RS04910
uniprot id: A0A172Q7M1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1811193:A0O21 RS03165
gene id: 1811193:A0O21_RS03165
uniprot id: A0A172Q6S0
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1811193:A0O21 RS01455
gene id: 1811193:A0O21_RS01455
uniprot id: A0A172Q5N7
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS06125
gene id: 1811193:A0O21_RS06125
uniprot id: A0A172Q862
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS04755
gene id: 1811193:A0O21_RS04755
uniprot id: A0A172Q7H1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1811193:A0O21 RS08055
gene id: 1811193:A0O21_RS08055
uniprot id: A0A172Q957
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1811193:A0O21 RS06110
gene id: 1811193:A0O21_RS06110
uniprot id: A0A172Q8A4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1811193:A0O21 RS00345
gene id: 1811193:A0O21_RS00345
uniprot id: A0A172Q5A9
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS07465
gene id: 1811193:A0O21_RS07465
uniprot id: A0A172Q8R4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1811193:A0O21 RS07865
gene id: 1811193:A0O21_RS07865
uniprot id: A0A172Q8Y4
names: Similarity
messages: Belongs to the UPF0340 family.

1811193:A0O21 RS10000
gene id: 1811193:A0O21_RS10000
uniprot id: A0A172QA31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1811193:A0O21 RS05125
gene id: 1811193:A0O21_RS05125
uniprot id: A0A172Q7K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1811193:A0O21 RS09315
gene id: 1811193:A0O21_RS09315
uniprot id: A0A172Q9Q4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1811193:A0O21 RS08315
gene id: 1811193:A0O21_RS08315
uniprot id: A0A172Q9D1
names: Similarity
messages: Belongs to the TelA family.

1811193:A0O21 RS09355
gene id: 1811193:A0O21_RS09355
uniprot id: A0A172Q9T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1811193:A0O21 RS03440
gene id: 1811193:A0O21_RS03440
uniprot id: A0A172Q6Q8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1811193:A0O21 RS03830
gene id: 1811193:A0O21_RS03830
uniprot id: A0A172Q6Z2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1811193:A0O21 RS07475
gene id: 1811193:A0O21_RS07475
uniprot id: A0A172Q8S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1811193:A0O21 RS10115
gene id: 1811193:A0O21_RS10115
uniprot id: A0A172QA62
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1811193:A0O21 RS07775
gene id: 1811193:A0O21_RS07775
uniprot id: A0A172Q8Z2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS10105
gene id: 1811193:A0O21_RS10105
uniprot id: A0A172QA18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1811193:A0O21 RS10125
gene id: 1811193:A0O21_RS10125
uniprot id: A0A172QA34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1811193:A0O21 RS08780
gene id: 1811193:A0O21_RS08780
uniprot id: A0A172Q9H9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1811193:A0O21 RS08260
gene id: 1811193:A0O21_RS08260
uniprot id: A0A172Q9C0
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS00770
gene id: 1811193:A0O21_RS00770
uniprot id: A0A172Q5I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1811193:A0O21 RS08990
gene id: 1811193:A0O21_RS08990
uniprot id: A0A172Q9Q1
names: Similarity
messages: Belongs to the thioesterase family.

1811193:A0O21 RS02060
gene id: 1811193:A0O21_RS02060
uniprot id: A0A172Q614
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1811193:A0O21 RS05695
gene id: 1811193:A0O21_RS05695
uniprot id: A0A172Q827
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1811193:A0O21 RS05425
gene id: 1811193:A0O21_RS05425
uniprot id: A0A172Q7P6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1811193:A0O21 RS09015
gene id: 1811193:A0O21_RS09015
uniprot id: A0A172Q9K7
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS09955
gene id: 1811193:A0O21_RS09955
uniprot id: A0A172QA33
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS08195
gene id: 1811193:A0O21_RS08195
uniprot id: A0A172Q969
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1811193:A0O21 RS04345
gene id: 1811193:A0O21_RS04345
uniprot id: A0A172Q737
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1811193:A0O21 RS03110
gene id: 1811193:A0O21_RS03110
uniprot id: A0A172Q6J1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1811193:A0O21 RS02605
gene id: 1811193:A0O21_RS02605
uniprot id: A0A172Q684
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS01585
gene id: 1811193:A0O21_RS01585
uniprot id: A0A172Q5Y3
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1811193:A0O21 RS00935
gene id: 1811193:A0O21_RS00935
uniprot id: A0A172Q5L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1811193:A0O21 RS03045
gene id: 1811193:A0O21_RS03045
uniprot id: A0A172Q6N5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1811193:A0O21 RS08565
gene id: 1811193:A0O21_RS08565
uniprot id: A0A172Q9D2
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1811193:A0O21 RS03970
gene id: 1811193:A0O21_RS03970
uniprot id: A0A172Q707
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1811193:A0O21 RS08030
gene id: 1811193:A0O21_RS08030
uniprot id: A0A172Q939
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1811193:A0O21 RS05080
gene id: 1811193:A0O21_RS05080
uniprot id: A0A172Q7R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1811193:A0O21 RS05820
gene id: 1811193:A0O21_RS05820
uniprot id: A0A172Q805
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1811193:A0O21 RS03565
gene id: 1811193:A0O21_RS03565
uniprot id: A0A172Q6Q4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS00910
gene id: 1811193:A0O21_RS00910
uniprot id: A0A172Q5F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1811193:A0O21 RS02775
gene id: 1811193:A0O21_RS02775
uniprot id: A0A172Q6I5
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS04915
gene id: 1811193:A0O21_RS04915
uniprot id: A0A172Q7H9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1811193:A0O21 RS04025
gene id: 1811193:A0O21_RS04025
uniprot id: A0A172Q715
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS00280
gene id: 1811193:A0O21_RS00280
uniprot id: A0A172Q537
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerD-like subfamily.
messages: Cytoplasm
messages: Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.

1811193:A0O21 RS03965
gene id: 1811193:A0O21_RS03965
uniprot id: A0A172Q6W7
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1811193:A0O21 RS08555
gene id: 1811193:A0O21_RS08555
uniprot id: A0A172Q986
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1811193:A0O21 RS05575
gene id: 1811193:A0O21_RS05575
uniprot id: A0A172Q7V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1811193:A0O21 RS00895
gene id: 1811193:A0O21_RS00895
uniprot id: A0A172Q5F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1811193:A0O21 RS06040
gene id: 1811193:A0O21_RS06040
uniprot id: A0A172Q859
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1811193:A0O21 RS07450
gene id: 1811193:A0O21_RS07450
uniprot id: A0A172Q8T5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS09310
gene id: 1811193:A0O21_RS09310
uniprot id: A0A172Q9L8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1811193:A0O21 RS06800
gene id: 1811193:A0O21_RS06800
uniprot id: A0A172Q8F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1811193:A0O21 RS02420
gene id: 1811193:A0O21_RS02420
uniprot id: A0A172Q6C6
names: Cofactor
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

1811193:A0O21 RS00270
gene id: 1811193:A0O21_RS00270
uniprot id: A0A172Q539
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1811193:A0O21 RS06100
gene id: 1811193:A0O21_RS06100
uniprot id: A0A172Q802
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1811193:A0O21 RS04270
gene id: 1811193:A0O21_RS04270
uniprot id: A0A172Q759
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1811193:A0O21 RS09885
gene id: 1811193:A0O21_RS09885
uniprot id: A0A172QAP6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1811193:A0O21 RS00375
gene id: 1811193:A0O21_RS00375
uniprot id: A0A172QAB2
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1811193:A0O21 RS03010
gene id: 1811193:A0O21_RS03010
uniprot id: A0A172QAD0
names: Subcellular Location Annotation
messages: cell wall

1811193:A0O21 RS01525
gene id: 1811193:A0O21_RS01525
uniprot id: A0A172Q5S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS05975
gene id: 1811193:A0O21_RS05975
uniprot id: A0A172Q821
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1811193:A0O21 RS09245
gene id: 1811193:A0O21_RS09245
uniprot id: A0A172Q9S0
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS01520
gene id: 1811193:A0O21_RS01520
uniprot id: A0A172QA52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1811193:A0O21 RS08210
gene id: 1811193:A0O21_RS08210
uniprot id: A0A172Q9B4
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS04000
gene id: 1811193:A0O21_RS04000
uniprot id: A0A172Q725
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS01810
gene id: 1811193:A0O21_RS01810
uniprot id: A0A172QAE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

1811193:A0O21 RS08325
gene id: 1811193:A0O21_RS08325
uniprot id: A0A172Q9B0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1811193:A0O21 RS09865
gene id: 1811193:A0O21_RS09865
uniprot id: A0A172Q9Y2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1811193:A0O21 RS09030
gene id: 1811193:A0O21_RS09030
uniprot id: A0A172Q9M6
names: Subcellular Location Annotation
messages: Cell membrane

1811193:A0O21 RS00295
gene id: 1811193:A0O21_RS00295
uniprot id: A0A172Q599
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1811193:A0O21 RS07860
gene id: 1811193:A0O21_RS07860
uniprot id: A0A172Q955
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1811193:A0O21 RS09950
gene id: 1811193:A0O21_RS09950
uniprot id: A0A172QA21
names: Subcellular Location Annotation
messages: Cytoplasm

1811193:A0O21 RS06210
gene id: 1811193:A0O21_RS06210
uniprot id: A0A172Q822
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1811193:A0O21 RS08760
gene id: 1811193:A0O21_RS08760
uniprot id: A0A172Q9E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1811193:A0O21 RS06715
gene id: 1811193:A0O21_RS06715
uniprot id: A0A172QAH2
names: Similarity
messages: Belongs to the YggT family.

1811193:A0O21 RS06515
gene id: 1811193:A0O21_RS06515
uniprot id: A0A172Q8C8
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS09880
gene id: 1811193:A0O21_RS09880
uniprot id: A0A172Q9X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1811193:A0O21 RS01220
gene id: 1811193:A0O21_RS01220
uniprot id: A0A172Q5M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1811193:A0O21 RS09295
gene id: 1811193:A0O21_RS09295
uniprot id: A0A172Q9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1811193:A0O21 RS02160
gene id: 1811193:A0O21_RS02160
uniprot id: A0A172Q608
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a pheromone, induces cells to develop competence for genetic transformation.
messages: Belongs to the ComC family.
messages: Secreted

1811193:A0O21 RS07070
gene id: 1811193:A0O21_RS07070
uniprot id: A0A172Q8N4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1811193:A0O21 RS06570
gene id: 1811193:A0O21_RS06570
uniprot id: A0A172Q8D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS07845
gene id: 1811193:A0O21_RS07845
uniprot id: A0A172Q8U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1811193:A0O21 RS00825
gene id: 1811193:A0O21_RS00825
uniprot id: A0A172Q5C8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1811193:A0O21 RS04280
gene id: 1811193:A0O21_RS04280
uniprot id: A0A172Q776
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1811193:A0O21 RS07005
gene id: 1811193:A0O21_RS07005
uniprot id: A0A172Q8H7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1811193:A0O21 RS05210
gene id: 1811193:A0O21_RS05210
uniprot id: A0A172Q7N7
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS04780
gene id: 1811193:A0O21_RS04780
uniprot id: A0A172QAF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1811193:A0O21 RS01815
gene id: 1811193:A0O21_RS01815
uniprot id: A0A172Q5X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1811193:A0O21 RS03585
gene id: 1811193:A0O21_RS03585
uniprot id: A0A172Q6P5
names: Similarity
messages: Belongs to the UPF0342 family.

1811193:A0O21 RS09625
gene id: 1811193:A0O21_RS09625
uniprot id: A0A172QA10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1811193:A0O21 RS00685
gene id: 1811193:A0O21_RS00685
uniprot id: A0A172Q5B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS08170
gene id: 1811193:A0O21_RS08170
uniprot id: A0A172Q983
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1811193:A0O21 RS07320
gene id: 1811193:A0O21_RS07320
uniprot id: A0A172Q8P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS06735
gene id: 1811193:A0O21_RS06735
uniprot id: A0A172Q8H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1811193:A0O21 RS09240
gene id: 1811193:A0O21_RS09240
uniprot id: A0A172QAH3
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1811193:A0O21 RS07880
gene id: 1811193:A0O21_RS07880
uniprot id: A0A172Q8X2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS06580
gene id: 1811193:A0O21_RS06580
uniprot id: A0A172Q888
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS03840
gene id: 1811193:A0O21_RS03840
uniprot id: A0A172Q733
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS00215
gene id: 1811193:A0O21_RS00215
uniprot id: A0A172Q529
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1811193:A0O21 RS02530
gene id: 1811193:A0O21_RS02530
uniprot id: A0A172Q6E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS06045
gene id: 1811193:A0O21_RS06045
uniprot id: A0A172Q7Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1811193:A0O21 RS00820
gene id: 1811193:A0O21_RS00820
uniprot id: A0A172Q5D1
names: Similarity
messages: Belongs to the asp23 family.

1811193:A0O21 RS08865
gene id: 1811193:A0O21_RS08865
uniprot id: A0A172Q9J3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1811193:A0O21 RS01025
gene id: 1811193:A0O21_RS01025
uniprot id: A0A172Q5H6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1811193:A0O21 RS06175
gene id: 1811193:A0O21_RS06175
uniprot id: A0A172Q885
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1811193:A0O21 RS07615
gene id: 1811193:A0O21_RS07615
uniprot id: A0A172QAL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS00905
gene id: 1811193:A0O21_RS00905
uniprot id: A0A172Q5G0
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1811193:A0O21 RS00265
gene id: 1811193:A0O21_RS00265
uniprot id: A0A172Q543
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1811193:A0O21 RS03180
gene id: 1811193:A0O21_RS03180
uniprot id: A0A172Q6K8
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS04010
gene id: 1811193:A0O21_RS04010
uniprot id: A0A172Q757
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS08455
gene id: 1811193:A0O21_RS08455
uniprot id: A0A172Q998
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1811193:A0O21 RS08935
gene id: 1811193:A0O21_RS08935
uniprot id: A0A172Q9H3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1811193:A0O21 RS10740
gene id: 1811193:A0O21_RS10740
uniprot id: A0A172QAH4
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS10465
gene id: 1811193:A0O21_RS10465
uniprot id: A0A172QA83
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS10060
gene id: 1811193:A0O21_RS10060
uniprot id: A0A172QA40
names: Similarity
messages: Belongs to the threonine synthase family.

1811193:A0O21 RS02205
gene id: 1811193:A0O21_RS02205
uniprot id: A0A172Q647
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

1811193:A0O21 RS01105
gene id: 1811193:A0O21_RS01105
uniprot id: A0A172Q5K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1811193:A0O21 RS10175
gene id: 1811193:A0O21_RS10175
uniprot id: A0A172QA44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1811193:A0O21 RS03595
gene id: 1811193:A0O21_RS03595
uniprot id: A0A172Q6Z7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1811193:A0O21 RS04700
gene id: 1811193:A0O21_RS04700
uniprot id: A0A172Q7G0
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS08610
gene id: 1811193:A0O21_RS08610
uniprot id: A0A172Q9C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1811193:A0O21 RS09200
gene id: 1811193:A0O21_RS09200
uniprot id: A0A172Q9N5
names: Similarity
messages: Belongs to the peptidase C40 family.

1811193:A0O21 RS00260
gene id: 1811193:A0O21_RS00260
uniprot id: A0A172Q530
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1811193:A0O21 RS07245
gene id: 1811193:A0O21_RS07245
uniprot id: A0A172Q8R9
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1811193:A0O21 RS10150
gene id: 1811193:A0O21_RS10150
uniprot id: A0A172QA92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1811193:A0O21 RS03005
gene id: 1811193:A0O21_RS03005
uniprot id: A0A172Q6N8
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

1811193:A0O21 RS05880
gene id: 1811193:A0O21_RS05880
uniprot id: A0A172Q835
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Homohexamer.

1811193:A0O21 RS07705
gene id: 1811193:A0O21_RS07705
uniprot id: A0A172Q8Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS05900
gene id: 1811193:A0O21_RS05900
uniprot id: A0A172QAD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1811193:A0O21 RS05995
gene id: 1811193:A0O21_RS05995
uniprot id: A0A172Q813
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 2 subfamily.
messages: Heterodimer of AddA and RexB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' -> 3' nuclease activity.

1811193:A0O21 RS10350
gene id: 1811193:A0O21_RS10350
uniprot id: A0A172QA26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1811193:A0O21 RS06000
gene id: 1811193:A0O21_RS06000
uniprot id: A0A172Q883
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1811193:A0O21 RS10095
gene id: 1811193:A0O21_RS10095
uniprot id: A0A172QA14
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1811193:A0O21 RS01965
gene id: 1811193:A0O21_RS01965
uniprot id: A0A172Q602
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1811193:A0O21 RS04630
gene id: 1811193:A0O21_RS04630
uniprot id: A0A172Q7D3
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1811193:A0O21 RS06340
gene id: 1811193:A0O21_RS06340
uniprot id: A0A172QAM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1811193:A0O21 RS05240
gene id: 1811193:A0O21_RS05240
uniprot id: A0A172Q7M7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1811193:A0O21 RS00810
gene id: 1811193:A0O21_RS00810
uniprot id: A0A172Q5E7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1811193:A0O21 RS10930
gene id: 1811193:A0O21_RS10930
uniprot id: A0A172Q7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1811193:A0O21 RS03460
gene id: 1811193:A0O21_RS03460
uniprot id: A0A172Q6S6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1811193:A0O21 RS10035
gene id: 1811193:A0O21_RS10035
uniprot id: A0A172QAK9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1811193:A0O21 RS01505
gene id: 1811193:A0O21_RS01505
uniprot id: A0A172QAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1811193:A0O21 RS04380
gene id: 1811193:A0O21_RS04380
uniprot id: A0A172Q779
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS02035
gene id: 1811193:A0O21_RS02035
uniprot id: A0A172Q5Z2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1811193:A0O21 RS03205
gene id: 1811193:A0O21_RS03205
uniprot id: A0A172Q6H4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1811193:A0O21 RS04405
gene id: 1811193:A0O21_RS04405
uniprot id: A0A172Q750
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1811193:A0O21 RS08270
gene id: 1811193:A0O21_RS08270
uniprot id: A0A172Q9A1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1811193:A0O21 RS00095
gene id: 1811193:A0O21_RS00095
uniprot id: A0A172Q533
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

1811193:A0O21 RS05990
gene id: 1811193:A0O21_RS05990
uniprot id: A0A172Q7Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1811193:A0O21 RS02715
gene id: 1811193:A0O21_RS02715
uniprot id: A0A172Q6C9
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS07080
gene id: 1811193:A0O21_RS07080
uniprot id: A0A172Q8L5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1811193:A0O21 RS09350
gene id: 1811193:A0O21_RS09350
uniprot id: A0A172Q9P9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS00235
gene id: 1811193:A0O21_RS00235
uniprot id: A0A172Q528
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1811193:A0O21 RS07735
gene id: 1811193:A0O21_RS07735
uniprot id: A0A172Q8T0
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS05895
gene id: 1811193:A0O21_RS05895
uniprot id: A0A172Q7X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1811193:A0O21 RS01595
gene id: 1811193:A0O21_RS01595
uniprot id: A0A172Q5Q9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

1811193:A0O21 RS08605
gene id: 1811193:A0O21_RS08605
uniprot id: A0A172Q996
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1811193:A0O21 RS06530
gene id: 1811193:A0O21_RS06530
uniprot id: A0A172Q8A7
names: Similarity
messages: Belongs to the UPF0213 family.

1811193:A0O21 RS09890
gene id: 1811193:A0O21_RS09890
uniprot id: A0A172QA41
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1811193:A0O21 RS07460
gene id: 1811193:A0O21_RS07460
uniprot id: A0A172Q8P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1811193:A0O21 RS08570
gene id: 1811193:A0O21_RS08570
uniprot id: A0A172Q9E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1811193:A0O21 RS00525
gene id: 1811193:A0O21_RS00525
uniprot id: A0A172Q588
names: Similarity
messages: Belongs to the asp23 family.

1811193:A0O21 RS06750
gene id: 1811193:A0O21_RS06750
uniprot id: A0A172Q8E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1811193:A0O21 RS06080
gene id: 1811193:A0O21_RS06080
uniprot id: A0A172Q838
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1811193:A0O21 RS06290
gene id: 1811193:A0O21_RS06290
uniprot id: A0A172Q890
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

1811193:A0O21 RS06265
gene id: 1811193:A0O21_RS06265
uniprot id: A0A172Q828
names: Similarity
messages: Belongs to the CitG/MdcB family.

1811193:A0O21 RS07505
gene id: 1811193:A0O21_RS07505
uniprot id: A0A172Q8W3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1811193:A0O21 RS08775
gene id: 1811193:A0O21_RS08775
uniprot id: A0A172Q9J1
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS00175
gene id: 1811193:A0O21_RS00175
uniprot id: A0A172Q522
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1811193:A0O21 RS01240
gene id: 1811193:A0O21_RS01240
uniprot id: A0A172Q5S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1811193:A0O21 RS10195
gene id: 1811193:A0O21_RS10195
uniprot id: A0A172QA39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1811193:A0O21 RS06740
gene id: 1811193:A0O21_RS06740
uniprot id: A0A172Q8I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

1811193:A0O21 RS03115
gene id: 1811193:A0O21_RS03115
uniprot id: A0A172Q6Q6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1811193:A0O21 RS00865
gene id: 1811193:A0O21_RS00865
uniprot id: A0A172Q5F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1811193:A0O21 RS04530
gene id: 1811193:A0O21_RS04530
uniprot id: A0A172Q7B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS07980
gene id: 1811193:A0O21_RS07980
uniprot id: A0A172Q927
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1811193:A0O21 RS04310
gene id: 1811193:A0O21_RS04310
uniprot id: A0A172Q770
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1811193:A0O21 RS02950
gene id: 1811193:A0O21_RS02950
uniprot id: A0A172Q6G1
names: Similarity
messages: Belongs to the peptidase C69 family.

1811193:A0O21 RS06540
gene id: 1811193:A0O21_RS06540
uniprot id: A0A172Q8B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1811193:A0O21 RS00415
gene id: 1811193:A0O21_RS00415
uniprot id: A0A172Q593
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1811193:A0O21 RS06390
gene id: 1811193:A0O21_RS06390
uniprot id: A0A172Q8D3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS06330
gene id: 1811193:A0O21_RS06330
uniprot id: A0A172Q880
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1811193:A0O21 RS03520
gene id: 1811193:A0O21_RS03520
uniprot id: A0A172Q6U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1811193:A0O21 RS03825
gene id: 1811193:A0O21_RS03825
uniprot id: A0A172Q6W0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1811193:A0O21 RS02475
gene id: 1811193:A0O21_RS02475
uniprot id: A0A172Q6D6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1811193:A0O21 RS07215
gene id: 1811193:A0O21_RS07215
uniprot id: A0A172QAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1811193:A0O21 RS01325
gene id: 1811193:A0O21_RS01325
uniprot id: A0A172Q5M3
names: Subcellular Location Annotation
messages: Secreted

1811193:A0O21 RS06890
gene id: 1811193:A0O21_RS06890
uniprot id: A0A172Q8J5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1811193:A0O21 RS07220
gene id: 1811193:A0O21_RS07220
uniprot id: A0A172Q8S0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1811193:A0O21 RS02685
gene id: 1811193:A0O21_RS02685
uniprot id: A0A172Q6B2
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1811193:A0O21 RS10520
gene id: 1811193:A0O21_RS10520
uniprot id: A0A172QA93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1811193:A0O21 RS04685
gene id: 1811193:A0O21_RS04685
uniprot id: A0A172Q7I0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

1811193:A0O21 RS03430
gene id: 1811193:A0O21_RS03430
uniprot id: A0A172Q6Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1811193:A0O21 RS05915
gene id: 1811193:A0O21_RS05915
uniprot id: A0A172Q844
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1811193:A0O21 RS02885
gene id: 1811193:A0O21_RS02885
uniprot id: A0A172Q6K5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1811193:A0O21 RS08895
gene id: 1811193:A0O21_RS08895
uniprot id: A0A172Q9K0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1811193:A0O21 RS01990
gene id: 1811193:A0O21_RS01990
uniprot id: A0A172Q5X4
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS05705
gene id: 1811193:A0O21_RS05705
uniprot id: A0A172Q811
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1811193:A0O21 RS08495
gene id: 1811193:A0O21_RS08495
uniprot id: A0A172Q9D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1811193:A0O21 RS05620
gene id: 1811193:A0O21_RS05620
uniprot id: A0A172Q7Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

1811193:A0O21 RS02020
gene id: 1811193:A0O21_RS02020
uniprot id: A0A172Q612
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1811193:A0O21 RS04110
gene id: 1811193:A0O21_RS04110
uniprot id: A0A172Q709
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1811193:A0O21 RS02130
gene id: 1811193:A0O21_RS02130
uniprot id: A0A172Q685
names: Similarity
messages: Belongs to the bacteriocin class IIA/YGNGV family.

1811193:A0O21 RS06590
gene id: 1811193:A0O21_RS06590
uniprot id: A0A172Q8J4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1811193:A0O21 RS02610
gene id: 1811193:A0O21_RS02610
uniprot id: A0A172Q6A9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1811193:A0O21 RS07795
gene id: 1811193:A0O21_RS07795
uniprot id: A0A172Q945
names: Similarity
messages: Belongs to the asp23 family.

1811193:A0O21 RS03990
gene id: 1811193:A0O21_RS03990
uniprot id: A0A172Q708
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1811193:A0O21 RS07675
gene id: 1811193:A0O21_RS07675
uniprot id: A0A172Q8W4
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS06105
gene id: 1811193:A0O21_RS06105
uniprot id: A0A172Q832
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1811193:A0O21 RS09915
gene id: 1811193:A0O21_RS09915
uniprot id: A0A172Q9Z9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1811193:A0O21 RS10070
gene id: 1811193:A0O21_RS10070
uniprot id: A0A172Q9Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1811193:A0O21 RS05775
gene id: 1811193:A0O21_RS05775
uniprot id: A0A172Q7V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1811193:A0O21 RS02565
gene id: 1811193:A0O21_RS02565
uniprot id: A0A172Q6E4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1811193:A0O21 RS04555
gene id: 1811193:A0O21_RS04555
uniprot id: A0A172Q7D8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerS subfamily.
messages: Cytoplasm
messages: FtsK is required for recombination.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.

1811193:A0O21 RS07445
gene id: 1811193:A0O21_RS07445
uniprot id: A0A172Q8T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1811193:A0O21 RS10165
gene id: 1811193:A0O21_RS10165
uniprot id: A0A172QA74
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1811193:A0O21 RS02660
gene id: 1811193:A0O21_RS02660
uniprot id: A0A172Q695
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1811193:A0O21 RS06640
gene id: 1811193:A0O21_RS06640
uniprot id: A0A172Q8C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1811193:A0O21 RS01390
gene id: 1811193:A0O21_RS01390
uniprot id: A0A172Q5V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1811193:A0O21 RS02305
gene id: 1811193:A0O21_RS02305
uniprot id: A0A172QAC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1811193:A0O21 RS06240
gene id: 1811193:A0O21_RS06240
uniprot id: A0A172Q879
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

1811193:A0O21 RS01255
gene id: 1811193:A0O21_RS01255
uniprot id: A0A172Q5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1811193:A0O21 RS03655
gene id: 1811193:A0O21_RS03655
uniprot id: A0A172Q6V0
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS00300
gene id: 1811193:A0O21_RS00300
uniprot id: A0A172Q542
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1811193:A0O21 RS03370
gene id: 1811193:A0O21_RS03370
uniprot id: A0A172Q6K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS06245
gene id: 1811193:A0O21_RS06245
uniprot id: A0A172Q837
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1811193:A0O21 RS06650
gene id: 1811193:A0O21_RS06650
uniprot id: A0A172Q8D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1811193:A0O21 RS10185
gene id: 1811193:A0O21_RS10185
uniprot id: A0A172QA63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1811193:A0O21 RS04590
gene id: 1811193:A0O21_RS04590
uniprot id: A0A172Q7B7
names: Subcellular Location Annotation
messages: Cytoplasm

1811193:A0O21 RS08785
gene id: 1811193:A0O21_RS08785
uniprot id: A0A172Q9C6
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
messages: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.

1811193:A0O21 RS03295
gene id: 1811193:A0O21_RS03295
uniprot id: A0A172Q6K7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1811193:A0O21 RS09210
gene id: 1811193:A0O21_RS09210
uniprot id: A0A172QAN7
names: Similarity
messages: Belongs to the carbamate kinase family.

1811193:A0O21 RS05245
gene id: 1811193:A0O21_RS05245
uniprot id: A0A172Q7U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1811193:A0O21 RS03660
gene id: 1811193:A0O21_RS03660
uniprot id: A0A172Q6Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS06810
gene id: 1811193:A0O21_RS06810
uniprot id: A0A172Q8G6
names: Similarity
messages: Belongs to the TrpC family.

1811193:A0O21 RS03690
gene id: 1811193:A0O21_RS03690
uniprot id: A0A172Q6R7
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS04115
gene id: 1811193:A0O21_RS04115
uniprot id: A0A172Q748
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1811193:A0O21 RS07780
gene id: 1811193:A0O21_RS07780
uniprot id: A0A172Q8Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1811193:A0O21 RS08875
gene id: 1811193:A0O21_RS08875
uniprot id: A0A172Q9G3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1811193:A0O21 RS05545
gene id: 1811193:A0O21_RS05545
uniprot id: A0A172Q7V7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1811193:A0O21 RS04970
gene id: 1811193:A0O21_RS04970
uniprot id: A0A172Q7N4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1811193:A0O21 RS10455
gene id: 1811193:A0O21_RS10455
uniprot id: A0A172QA45
names: Subcellular Location Annotation
messages: Cytoplasm

1811193:A0O21 RS00860
gene id: 1811193:A0O21_RS00860
uniprot id: A0A172Q5F0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1811193:A0O21 RS00990
gene id: 1811193:A0O21_RS00990
uniprot id: A0A172Q5F4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1811193:A0O21 RS09215
gene id: 1811193:A0O21_RS09215
uniprot id: A0A172Q9H8
names: Similarity
messages: Belongs to the agmatine deiminase family.

1811193:A0O21 RS09685
gene id: 1811193:A0O21_RS09685
uniprot id: A0A172Q9Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1811193:A0O21 RS00200
gene id: 1811193:A0O21_RS00200
uniprot id: A0A172Q523
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS09300
gene id: 1811193:A0O21_RS09300
uniprot id: A0A172Q9S9
names: Similarity
messages: Belongs to the CinA family.

1811193:A0O21 RS08475
gene id: 1811193:A0O21_RS08475
uniprot id: A0A172Q954
names: Similarity
messages: Belongs to the UPF0177 family.

1811193:A0O21 RS07470
gene id: 1811193:A0O21_RS07470
uniprot id: A0A172Q901
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1811193:A0O21 RS01725
gene id: 1811193:A0O21_RS01725
uniprot id: A0A172Q5V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0298 family.
messages: Cytoplasm

1811193:A0O21 RS00830
gene id: 1811193:A0O21_RS00830
uniprot id: A0A172Q5J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1811193:A0O21 RS01045
gene id: 1811193:A0O21_RS01045
uniprot id: A0A172Q5I6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS06375
gene id: 1811193:A0O21_RS06375
uniprot id: A0A172Q878
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1811193:A0O21 RS02615
gene id: 1811193:A0O21_RS02615
uniprot id: A0A172Q674
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1811193:A0O21 RS02890
gene id: 1811193:A0O21_RS02890
uniprot id: A0A172Q6C1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1811193:A0O21 RS02285
gene id: 1811193:A0O21_RS02285
uniprot id: A0A172Q628
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1811193:A0O21 RS08520
gene id: 1811193:A0O21_RS08520
uniprot id: A0A172Q9D3
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1811193:A0O21 RS07695
gene id: 1811193:A0O21_RS07695
uniprot id: A0A172Q925
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS09320
gene id: 1811193:A0O21_RS09320
uniprot id: A0A172Q9Q6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1811193:A0O21 RS06060
gene id: 1811193:A0O21_RS06060
uniprot id: A0A172Q833
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1811193:A0O21 RS04285
gene id: 1811193:A0O21_RS04285
uniprot id: A0A172Q784
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a set of proteins in which some residues (ACT_SITE, NP_BIND, REGION and BINDING) are not conserved.

1811193:A0O21 RS06760
gene id: 1811193:A0O21_RS06760
uniprot id: A0A172Q8F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1811193:A0O21 RS00675
gene id: 1811193:A0O21_RS00675
uniprot id: A0A172Q5E2
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1811193:A0O21 RS06165
gene id: 1811193:A0O21_RS06165
uniprot id: A0A172Q854
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS08400
gene id: 1811193:A0O21_RS08400
uniprot id: A0A172Q9A0
names: Similarity
messages: Belongs to the WXG100 family.

1811193:A0O21 RS02895
gene id: 1811193:A0O21_RS02895
uniprot id: A0A172Q6F1
names: Similarity
messages: Belongs to the RutC family.

1811193:A0O21 RS02245
gene id: 1811193:A0O21_RS02245
uniprot id: A0A172QAF2
names: Similarity
messages: Belongs to the CvfB family.

1811193:A0O21 RS05965
gene id: 1811193:A0O21_RS05965
uniprot id: A0A172Q7Y6
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

1811193:A0O21 RS02655
gene id: 1811193:A0O21_RS02655
uniprot id: A0A172Q6B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1811193:A0O21 RS09375
gene id: 1811193:A0O21_RS09375
uniprot id: A0A172Q9R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1811193:A0O21 RS04760
gene id: 1811193:A0O21_RS04760
uniprot id: A0A172Q7I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1811193:A0O21 RS01125
gene id: 1811193:A0O21_RS01125
uniprot id: A0A172Q5J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1811193:A0O21 RS07040
gene id: 1811193:A0O21_RS07040
uniprot id: A0A172Q8K0
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS03195
gene id: 1811193:A0O21_RS03195
uniprot id: A0A172Q6N1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1811193:A0O21 RS06680
gene id: 1811193:A0O21_RS06680
uniprot id: A0A172Q8G2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1811193:A0O21 RS03875
gene id: 1811193:A0O21_RS03875
uniprot id: A0A172Q6W8
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

1811193:A0O21 RS10160
gene id: 1811193:A0O21_RS10160
uniprot id: A0A172QA59
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1811193:A0O21 RS04390
gene id: 1811193:A0O21_RS04390
uniprot id: A0A172Q799
names: Subcellular Location Annotation
messages: Cell surface

1811193:A0O21 RS01110
gene id: 1811193:A0O21_RS01110
uniprot id: A0A172Q5K7
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS06725
gene id: 1811193:A0O21_RS06725
uniprot id: A0A172Q8C5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1811193:A0O21 RS04245
gene id: 1811193:A0O21_RS04245
uniprot id: A0A172Q718
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1811193:A0O21 RS06535
gene id: 1811193:A0O21_RS06535
uniprot id: A0A172Q8I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

1811193:A0O21 RS08880
gene id: 1811193:A0O21_RS08880
uniprot id: A0A172Q9N1
names: Similarity
messages: Belongs to the CtsR family.

1811193:A0O21 RS06280
gene id: 1811193:A0O21_RS06280
uniprot id: A0A172Q873
names: Subcellular Location Annotation
messages: Cytoplasm

1811193:A0O21 RS10085
gene id: 1811193:A0O21_RS10085
uniprot id: A0A172QA43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1811193:A0O21 RS04500
gene id: 1811193:A0O21_RS04500
uniprot id: A0A172Q7C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1811193:A0O21 RS05790
gene id: 1811193:A0O21_RS05790
uniprot id: A0A172Q824
names: Similarity
messages: Belongs to the PemK/MazF family.

1811193:A0O21 RS08765
gene id: 1811193:A0O21_RS08765
uniprot id: A0A172Q9L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1811193:A0O21 RS03105
gene id: 1811193:A0O21_RS03105
uniprot id: A0A172Q6F9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1811193:A0O21 RS07230
gene id: 1811193:A0O21_RS07230
uniprot id: A0A172Q8K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1811193:A0O21 RS06300
gene id: 1811193:A0O21_RS06300
uniprot id: A0A172Q881
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS10415
gene id: 1811193:A0O21_RS10415
uniprot id: A0A172QA75
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS00430
gene id: 1811193:A0O21_RS00430
uniprot id: A0A172Q570
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1811193:A0O21 RS07250
gene id: 1811193:A0O21_RS07250
uniprot id: A0A172Q8J7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1811193:A0O21 RS01565
gene id: 1811193:A0O21_RS01565
uniprot id: A0A172Q5T4
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1811193:A0O21 RS07035
gene id: 1811193:A0O21_RS07035
uniprot id: A0A172Q8H1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS03375
gene id: 1811193:A0O21_RS03375
uniprot id: A0A172Q6P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

1811193:A0O21 RS07635
gene id: 1811193:A0O21_RS07635
uniprot id: A0A172Q8R1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1811193:A0O21 RS03525
gene id: 1811193:A0O21_RS03525
uniprot id: A0A172Q6X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1811193:A0O21 RS02355
gene id: 1811193:A0O21_RS02355
uniprot id: A0A172Q6A7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1811193:A0O21 RS00140
gene id: 1811193:A0O21_RS00140
uniprot id: A0A172Q506
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

1811193:A0O21 RS04445
gene id: 1811193:A0O21_RS04445
uniprot id: A0A172Q7A5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1811193:A0O21 RS05740
gene id: 1811193:A0O21_RS05740
uniprot id: A0A172Q814
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1811193:A0O21 RS08090
gene id: 1811193:A0O21_RS08090
uniprot id: A0A172QAD9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS10090
gene id: 1811193:A0O21_RS10090
uniprot id: A0A172Q9W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1811193:A0O21 RS07290
gene id: 1811193:A0O21_RS07290
uniprot id: A0A172Q8Q0
names: Similarity
messages: Belongs to the peptidase C1 family.

1811193:A0O21 RS08395
gene id: 1811193:A0O21_RS08395
uniprot id: A0A172Q987
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EsaA family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS04995
gene id: 1811193:A0O21_RS04995
uniprot id: A0A172Q7N5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS02490
gene id: 1811193:A0O21_RS02490
uniprot id: A0A172Q688
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS06385
gene id: 1811193:A0O21_RS06385
uniprot id: A0A172Q886
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1811193:A0O21 RS07055
gene id: 1811193:A0O21_RS07055
uniprot id: A0A172Q8K8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS09365
gene id: 1811193:A0O21_RS09365
uniprot id: A0A172Q9M8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1811193:A0O21 RS01150
gene id: 1811193:A0O21_RS01150
uniprot id: A0A172Q5N1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1811193:A0O21 RS07375
gene id: 1811193:A0O21_RS07375
uniprot id: A0A172Q8Q8
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS02240
gene id: 1811193:A0O21_RS02240
uniprot id: A0A172Q698
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1811193:A0O21 RS03060
gene id: 1811193:A0O21_RS03060
uniprot id: A0A172Q6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1811193:A0O21 RS03065
gene id: 1811193:A0O21_RS03065
uniprot id: A0A172Q6I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1811193:A0O21 RS03085
gene id: 1811193:A0O21_RS03085
uniprot id: A0A172Q6G6
names: Subcellular Location Annotation
messages: cell wall

1811193:A0O21 RS10120
gene id: 1811193:A0O21_RS10120
uniprot id: A0A172Q9Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1811193:A0O21 RS07510
gene id: 1811193:A0O21_RS07510
uniprot id: A0A172Q8Q1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1811193:A0O21 RS06630
gene id: 1811193:A0O21_RS06630
uniprot id: A0A172Q896
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1811193:A0O21 RS00645
gene id: 1811193:A0O21_RS00645
uniprot id: A0A172Q5A6
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS04980
gene id: 1811193:A0O21_RS04980
uniprot id: A0A172Q7G3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1811193:A0O21 RS03035
gene id: 1811193:A0O21_RS03035
uniprot id: A0A172Q6I6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS00075
gene id: 1811193:A0O21_RS00075
uniprot id: A0A172Q4Z9
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

1811193:A0O21 RS06130
gene id: 1811193:A0O21_RS06130
uniprot id: A0A172Q817
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1811193:A0O21 RS07490
gene id: 1811193:A0O21_RS07490
uniprot id: A0A172Q8Q9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1811193:A0O21 RS10330
gene id: 1811193:A0O21_RS10330
uniprot id: A0A172QAA6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1811193:A0O21 RS06915
gene id: 1811193:A0O21_RS06915
uniprot id: A0A172Q8I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1811193:A0O21 RS09960
gene id: 1811193:A0O21_RS09960
uniprot id: A0A172Q9X0
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS09145
gene id: 1811193:A0O21_RS09145
uniprot id: A0A172Q9L7
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS01760
gene id: 1811193:A0O21_RS01760
uniprot id: A0A172Q5W1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1811193:A0O21 RS00610
gene id: 1811193:A0O21_RS00610
uniprot id: A0A172Q587
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S15 family.
messages: Cytoplasm
messages: Homodimer.
messages: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

1811193:A0O21 RS10190
gene id: 1811193:A0O21_RS10190
uniprot id: A0A172Q9Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1811193:A0O21 RS00765
gene id: 1811193:A0O21_RS00765
uniprot id: A0A172Q5B4
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1811193:A0O21 RS10335
gene id: 1811193:A0O21_RS10335
uniprot id: A0A172QA48
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1811193:A0O21 RS00580
gene id: 1811193:A0O21_RS00580
uniprot id: A0A172Q595
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS02280
gene id: 1811193:A0O21_RS02280
uniprot id: A0A172Q659
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1811193:A0O21 RS02785
gene id: 1811193:A0O21_RS02785
uniprot id: A0A172Q6D2
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1811193:A0O21 RS00605
gene id: 1811193:A0O21_RS00605
uniprot id: A0A172Q5F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1811193:A0O21 RS08595
gene id: 1811193:A0O21_RS08595
uniprot id: A0A172Q9F9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1811193:A0O21 RS06220
gene id: 1811193:A0O21_RS06220
uniprot id: A0A172Q8C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1811193:A0O21 RS01410
gene id: 1811193:A0O21_RS01410
uniprot id: A0A172Q5T0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1811193:A0O21 RS08080
gene id: 1811193:A0O21_RS08080
uniprot id: A0A172Q941
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1811193:A0O21 RS08805
gene id: 1811193:A0O21_RS08805
uniprot id: A0A172QAN3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS00210
gene id: 1811193:A0O21_RS00210
uniprot id: A0A172Q521
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1811193:A0O21 RS04715
gene id: 1811193:A0O21_RS04715
uniprot id: A0A172Q7B8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1811193:A0O21 RS01820
gene id: 1811193:A0O21_RS01820
uniprot id: A0A172Q5U4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1811193:A0O21 RS05700
gene id: 1811193:A0O21_RS05700
uniprot id: A0A172Q7X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1811193:A0O21 RS05000
gene id: 1811193:A0O21_RS05000
uniprot id: A0A172Q7G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1811193:A0O21 RS05850
gene id: 1811193:A0O21_RS05850
uniprot id: A0A172QAK0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1811193:A0O21 RS07380
gene id: 1811193:A0O21_RS07380
uniprot id: A0A172Q8U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1811193:A0O21 RS09290
gene id: 1811193:A0O21_RS09290
uniprot id: A0A172Q9V1
names: Similarity
messages: Belongs to the ArsC family.

1811193:A0O21 RS06090
gene id: 1811193:A0O21_RS06090
uniprot id: A0A172Q867
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS08295
gene id: 1811193:A0O21_RS08295
uniprot id: A0A172Q985
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1811193:A0O21 RS07150
gene id: 1811193:A0O21_RS07150
uniprot id: A0A172Q8K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1811193:A0O21 RS02275
gene id: 1811193:A0O21_RS02275
uniprot id: A0A172Q633
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1811193:A0O21 RS07905
gene id: 1811193:A0O21_RS07905
uniprot id: A0A172Q8V9
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

1811193:A0O21 RS00440
gene id: 1811193:A0O21_RS00440
uniprot id: A0A172Q567
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS07600
gene id: 1811193:A0O21_RS07600
uniprot id: A0A172Q8W6
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily.
messages: Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system.

1811193:A0O21 RS01225
gene id: 1811193:A0O21_RS01225
uniprot id: A0A172Q5K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1811193:A0O21 RS02580
gene id: 1811193:A0O21_RS02580
uniprot id: A0A172Q694
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1811193:A0O21 RS01905
gene id: 1811193:A0O21_RS01905
uniprot id: A0A172Q5Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1811193:A0O21 RS02710
gene id: 1811193:A0O21_RS02710
uniprot id: A0A172Q6A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1811193:A0O21 RS02055
gene id: 1811193:A0O21_RS02055
uniprot id: A0A172Q5Y4
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1811193:A0O21 RS01845
gene id: 1811193:A0O21_RS01845
uniprot id: A0A172Q5Y1
names: Similarity
messages: Belongs to the ArsC family.

1811193:A0O21 RS09380
gene id: 1811193:A0O21_RS09380
uniprot id: A0A172Q9T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1811193:A0O21 RS05780
gene id: 1811193:A0O21_RS05780
uniprot id: A0A172Q7Z1
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS00395
gene id: 1811193:A0O21_RS00395
uniprot id: A0A172Q554
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1811193:A0O21 RS08405
gene id: 1811193:A0O21_RS08405
uniprot id: A0A172Q9B5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1811193:A0O21 RS02325
gene id: 1811193:A0O21_RS02325
uniprot id: A0A172Q6A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1811193:A0O21 RS09360
gene id: 1811193:A0O21_RS09360
uniprot id: A0A172Q9T3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1811193:A0O21 RS01090
gene id: 1811193:A0O21_RS01090
uniprot id: A0A172Q5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS02705
gene id: 1811193:A0O21_RS02705
uniprot id: A0A172Q6B8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1811193:A0O21 RS05390
gene id: 1811193:A0O21_RS05390
uniprot id: A0A172Q7V0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1811193:A0O21 RS01060
gene id: 1811193:A0O21_RS01060
uniprot id: A0A172Q5J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

1811193:A0O21 RS05130
gene id: 1811193:A0O21_RS05130
uniprot id: A0A172QAJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1811193:A0O21 RS06355
gene id: 1811193:A0O21_RS06355
uniprot id: A0A172Q892
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1811193:A0O21 RS03150
gene id: 1811193:A0O21_RS03150
uniprot id: A0A172Q6R0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1811193:A0O21 RS02560
gene id: 1811193:A0O21_RS02560
uniprot id: A0A172Q666
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1811193:A0O21 RS09275
gene id: 1811193:A0O21_RS09275
uniprot id: A0A172Q9R5
names: Similarity
messages: Belongs to the UPF0297 family.

1811193:A0O21 RS02315
gene id: 1811193:A0O21_RS02315
uniprot id: A0A172Q6A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1811193:A0O21 RS00255
gene id: 1811193:A0O21_RS00255
uniprot id: A0A172Q545
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS04890
gene id: 1811193:A0O21_RS04890
uniprot id: A0A172Q7E1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1811193:A0O21 RS01940
gene id: 1811193:A0O21_RS01940
uniprot id: A0A172Q646
names: Similarity
messages: Belongs to the CapA family.

1811193:A0O21 RS09910
gene id: 1811193:A0O21_RS09910
uniprot id: A0A172Q9V9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1811193:A0O21 RS01295
gene id: 1811193:A0O21_RS01295
uniprot id: A0A172Q5L0
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1811193:A0O21 RS03685
gene id: 1811193:A0O21_RS03685
uniprot id: A0A172Q701
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS10100
gene id: 1811193:A0O21_RS10100
uniprot id: A0A172QA81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1811193:A0O21 RS02745
gene id: 1811193:A0O21_RS02745
uniprot id: A0A172Q6C7
names: Similarity
messages: Belongs to the FemABX family.

1811193:A0O21 RS04950
gene id: 1811193:A0O21_RS04950
uniprot id: A0A172Q7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS01250
gene id: 1811193:A0O21_RS01250
uniprot id: A0A172Q5M2
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1811193:A0O21 RS02190
gene id: 1811193:A0O21_RS02190
uniprot id: A0A172Q641
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS05200
gene id: 1811193:A0O21_RS05200
uniprot id: A0A172Q7N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1811193:A0O21 RS07655
gene id: 1811193:A0O21_RS07655
uniprot id: A0A172Q8Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Ycf16 family.
messages: Membrane

1811193:A0O21 RS05865
gene id: 1811193:A0O21_RS05865
uniprot id: A0A172Q856
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1811193:A0O21 RS07855
gene id: 1811193:A0O21_RS07855
uniprot id: A0A172Q8X7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1811193:A0O21 RS08390
gene id: 1811193:A0O21_RS08390
uniprot id: A0A172Q956
names: Similarity
messages: Belongs to the EssA family.

1811193:A0O21 RS05615
gene id: 1811193:A0O21_RS05615
uniprot id: A0A172QAL0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.

1811193:A0O21 RS03355
gene id: 1811193:A0O21_RS03355
uniprot id: A0A172Q6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS00620
gene id: 1811193:A0O21_RS00620
uniprot id: A0A172Q5D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS02875
gene id: 1811193:A0O21_RS02875
uniprot id: A0A172QAG0
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

1811193:A0O21 RS06335
gene id: 1811193:A0O21_RS06335
uniprot id: A0A172Q8B7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1811193:A0O21 RS00565
gene id: 1811193:A0O21_RS00565
uniprot id: A0A172Q598
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1811193:A0O21 RS10080
gene id: 1811193:A0O21_RS10080
uniprot id: A0A172QA25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1811193:A0O21 RS03455
gene id: 1811193:A0O21_RS03455
uniprot id: A0A172Q6N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS03800
gene id: 1811193:A0O21_RS03800
uniprot id: A0A172Q6X2
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1811193:A0O21 RS05065
gene id: 1811193:A0O21_RS05065
uniprot id: A0A172Q7P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1811193:A0O21 RS04460
gene id: 1811193:A0O21_RS04460
uniprot id: A0A172Q760
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS03490
gene id: 1811193:A0O21_RS03490
uniprot id: A0A172Q6R9
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1811193:A0O21 RS07665
gene id: 1811193:A0O21_RS07665
uniprot id: A0A172Q8S8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1811193:A0O21 RS02740
gene id: 1811193:A0O21_RS02740
uniprot id: A0A172Q6J2
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS03040
gene id: 1811193:A0O21_RS03040
uniprot id: A0A172Q6J6
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1811193:A0O21 RS00455
gene id: 1811193:A0O21_RS00455
uniprot id: A0A172QA38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1811193:A0O21 RS05410
gene id: 1811193:A0O21_RS05410
uniprot id: A0A172Q7S2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1811193:A0O21 RS04695
gene id: 1811193:A0O21_RS04695
uniprot id: A0A172Q7B9
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS08660
gene id: 1811193:A0O21_RS08660
uniprot id: A0A172QAM4
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS03575
gene id: 1811193:A0O21_RS03575
uniprot id: A0A172Q6V1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1811193:A0O21 RS10200
gene id: 1811193:A0O21_RS10200
uniprot id: A0A172QA99
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1811193:A0O21 RS06575
gene id: 1811193:A0O21_RS06575
uniprot id: A0A172Q8G0
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1811193:A0O21 RS07875
gene id: 1811193:A0O21_RS07875
uniprot id: A0A172Q919
names: Similarity
messages: Belongs to the ThiD family.

1811193:A0O21 RS08655
gene id: 1811193:A0O21_RS08655
uniprot id: A0A172Q9G0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1811193:A0O21 RS00515
gene id: 1811193:A0O21_RS00515
uniprot id: A0A172Q586
names: Similarity
messages: Belongs to the asp23 family.

1811193:A0O21 RS06160
gene id: 1811193:A0O21_RS06160
uniprot id: A0A172Q8B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1811193:A0O21 RS01850
gene id: 1811193:A0O21_RS01850
uniprot id: A0A172Q5Y8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1811193:A0O21 RS00870
gene id: 1811193:A0O21_RS00870
uniprot id: A0A172Q5D8
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1811193:A0O21 RS00710
gene id: 1811193:A0O21_RS00710
uniprot id: A0A172Q5A5
names: Similarity
messages: Belongs to the UPF0177 family.

1811193:A0O21 RS03860
gene id: 1811193:A0O21_RS03860
uniprot id: A0A172Q6Z0
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS10045
gene id: 1811193:A0O21_RS10045
uniprot id: A0A172QA05
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1811193:A0O21 RS06440
gene id: 1811193:A0O21_RS06440
uniprot id: A0A172Q8E3
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS07810
gene id: 1811193:A0O21_RS07810
uniprot id: A0A172Q916
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1811193:A0O21 RS02955
gene id: 1811193:A0O21_RS02955
uniprot id: A0A172Q6M9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1811193:A0O21 RS05825
gene id: 1811193:A0O21_RS05825
uniprot id: A0A172Q7W6
names: Similarity
messages: Belongs to the TPP enzyme family.

1811193:A0O21 RS06700
gene id: 1811193:A0O21_RS06700
uniprot id: A0A172Q8L8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1811193:A0O21 RS03960
gene id: 1811193:A0O21_RS03960
uniprot id: A0A172Q746
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1811193:A0O21 RS08615
gene id: 1811193:A0O21_RS08615
uniprot id: A0A172Q9D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1811193:A0O21 RS08550
gene id: 1811193:A0O21_RS08550
uniprot id: A0A172Q9E0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1811193:A0O21 RS03135
gene id: 1811193:A0O21_RS03135
uniprot id: A0A172Q6H6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1811193:A0O21 RS05835
gene id: 1811193:A0O21_RS05835
uniprot id: A0A172Q809
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1811193:A0O21 RS09590
gene id: 1811193:A0O21_RS09590
uniprot id: A0A172Q9V8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1811193:A0O21 RS06970
gene id: 1811193:A0O21_RS06970
uniprot id: A0A172Q8R3
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS01165
gene id: 1811193:A0O21_RS01165
uniprot id: A0A172Q5L4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1811193:A0O21 RS02090
gene id: 1811193:A0O21_RS02090
uniprot id: A0A172Q603
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Cell membrane
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1811193:A0O21 RS00500
gene id: 1811193:A0O21_RS00500
uniprot id: A0A172Q565
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1811193:A0O21 RS08130
gene id: 1811193:A0O21_RS08130
uniprot id: A0A172Q943
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1811193:A0O21 RS05090
gene id: 1811193:A0O21_RS05090
uniprot id: A0A172Q7Q1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS08135
gene id: 1811193:A0O21_RS08135
uniprot id: A0A172Q951
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1811193:A0O21 RS03185
gene id: 1811193:A0O21_RS03185
uniprot id: A0A172Q6I9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1811193:A0O21 RS05235
gene id: 1811193:A0O21_RS05235
uniprot id: A0A172Q7K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1811193:A0O21 RS00330
gene id: 1811193:A0O21_RS00330
uniprot id: A0A172Q547
names: Subcellular Location Annotation
messages: Cell membrane

1811193:A0O21 RS00900
gene id: 1811193:A0O21_RS00900
uniprot id: A0A172Q5I0
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1811193:A0O21 RS09585
gene id: 1811193:A0O21_RS09585
uniprot id: A0A172Q9V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS06615
gene id: 1811193:A0O21_RS06615
uniprot id: A0A172Q8E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1811193:A0O21 RS06815
gene id: 1811193:A0O21_RS06815
uniprot id: A0A172Q8L2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS02010
gene id: 1811193:A0O21_RS02010
uniprot id: A0A172Q630
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS07180
gene id: 1811193:A0O21_RS07180
uniprot id: A0A172Q8N0
names: Function
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1811193:A0O21 RS03820
gene id: 1811193:A0O21_RS03820
uniprot id: A0A172Q6X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS03130
gene id: 1811193:A0O21_RS03130
uniprot id: A0A172Q6K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1811193:A0O21 RS03100
gene id: 1811193:A0O21_RS03100
uniprot id: A0A172Q6P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

1811193:A0O21 RS06880
gene id: 1811193:A0O21_RS06880
uniprot id: A0A172Q8F5
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS01710
gene id: 1811193:A0O21_RS01710
uniprot id: A0A172Q605
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1811193:A0O21 RS03415
gene id: 1811193:A0O21_RS03415
uniprot id: A0A172Q6S1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1811193:A0O21 RS02850
gene id: 1811193:A0O21_RS02850
uniprot id: A0A172Q6E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1811193:A0O21 RS06720
gene id: 1811193:A0O21_RS06720
uniprot id: A0A172Q8H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1811193:A0O21 RS10460
gene id: 1811193:A0O21_RS10460
uniprot id: A0A172QA84
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS07610
gene id: 1811193:A0O21_RS07610
uniprot id: A0A172Q8V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS01245
gene id: 1811193:A0O21_RS01245
uniprot id: A0A172Q5J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1811193:A0O21 RS07060
gene id: 1811193:A0O21_RS07060
uniprot id: A0A172QAH9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS04260
gene id: 1811193:A0O21_RS04260
uniprot id: A0A172Q761
names: Similarity
messages: Belongs to the UPF0758 family.

1811193:A0O21 RS08000
gene id: 1811193:A0O21_RS08000
uniprot id: A0A172Q906
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1811193:A0O21 RS07275
gene id: 1811193:A0O21_RS07275
uniprot id: A0A172Q8T1
names: Similarity
messages: Belongs to the UPF0398 family.

1811193:A0O21 RS01985
gene id: 1811193:A0O21_RS01985
uniprot id: A0A172Q606
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1811193:A0O21 RS00670
gene id: 1811193:A0O21_RS00670
uniprot id: A0A172Q5B9
names: Similarity
messages: Belongs to the thioredoxin family.

1811193:A0O21 RS05485
gene id: 1811193:A0O21_RS05485
uniprot id: A0A172Q7V5
names: Similarity
messages: Belongs to the UPF0177 family.

1811193:A0O21 RS06675
gene id: 1811193:A0O21_RS06675
uniprot id: A0A172Q8F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

1811193:A0O21 RS01265
gene id: 1811193:A0O21_RS01265
uniprot id: A0A172Q5N5
names: Similarity
messages: Belongs to the group II decarboxylase family.

1811193:A0O21 RS04125
gene id: 1811193:A0O21_RS04125
uniprot id: A0A172Q778
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS04340
gene id: 1811193:A0O21_RS04340
uniprot id: A0A172Q7B2
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1811193:A0O21 RS03835
gene id: 1811193:A0O21_RS03835
uniprot id: A0A172Q704
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1811193:A0O21 RS03405
gene id: 1811193:A0O21_RS03405
uniprot id: A0A172Q6M7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1811193:A0O21 RS08380
gene id: 1811193:A0O21_RS08380
uniprot id: A0A172Q9C1
names: Similarity
messages: Belongs to the EssB family.

1811193:A0O21 RS04785
gene id: 1811193:A0O21_RS04785
uniprot id: A0A172Q7L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1811193:A0O21 RS01300
gene id: 1811193:A0O21_RS01300
uniprot id: A0A172Q5N6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS08065
gene id: 1811193:A0O21_RS08065
uniprot id: A0A172Q8Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1811193:A0O21 RS06215
gene id: 1811193:A0O21_RS06215
uniprot id: A0A172Q850
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS06425
gene id: 1811193:A0O21_RS06425
uniprot id: A0A172Q887
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS08275
gene id: 1811193:A0O21_RS08275
uniprot id: A0A172Q990
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS09900
gene id: 1811193:A0O21_RS09900
uniprot id: A0A172QA11
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS06550
gene id: 1811193:A0O21_RS06550
uniprot id: A0A172QAL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1811193:A0O21 RS05060
gene id: 1811193:A0O21_RS05060
uniprot id: A0A172Q7M8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1811193:A0O21 RS03420
gene id: 1811193:A0O21_RS03420
uniprot id: A0A172Q6V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1811193:A0O21 RS03425
gene id: 1811193:A0O21_RS03425
uniprot id: A0A172Q6L4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1811193:A0O21 RS04545
gene id: 1811193:A0O21_RS04545
uniprot id: A0A172Q783
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1811193:A0O21 RS02800
gene id: 1811193:A0O21_RS02800
uniprot id: A0A172Q6J3
names: Similarity
messages: Belongs to the PdxA family. PdxA2 subfamily.

1811193:A0O21 RS06010
gene id: 1811193:A0O21_RS06010
uniprot id: A0A172Q816
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1811193:A0O21 RS09985
gene id: 1811193:A0O21_RS09985
uniprot id: A0A172Q9Z4
names: Similarity
messages: Belongs to the GARS family.

1811193:A0O21 RS06250
gene id: 1811193:A0O21_RS06250
uniprot id: A0A172Q872
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1811193:A0O21 RS03635
gene id: 1811193:A0O21_RS03635
uniprot id: A0A172Q6Z1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

1811193:A0O21 RS06135
gene id: 1811193:A0O21_RS06135
uniprot id: A0A172Q852
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1811193:A0O21 RS06910
gene id: 1811193:A0O21_RS06910
uniprot id: A0A172Q8Q3
names: Similarity
messages: Belongs to the peptidase S16 family.

1811193:A0O21 RS06555
gene id: 1811193:A0O21_RS06555
uniprot id: A0A172Q8D8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1811193:A0O21 RS03715
gene id: 1811193:A0O21_RS03715
uniprot id: A0A172Q6V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS01840
gene id: 1811193:A0O21_RS01840
uniprot id: A0A172Q600
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1811193:A0O21 RS10205
gene id: 1811193:A0O21_RS10205
uniprot id: A0A172QA36
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1811193:A0O21 RS05120
gene id: 1811193:A0O21_RS05120
uniprot id: A0A172Q7H6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS04815
gene id: 1811193:A0O21_RS04815
uniprot id: A0A172Q7J3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1811193:A0O21 RS06565
gene id: 1811193:A0O21_RS06565
uniprot id: A0A172Q8D2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1811193:A0O21 RS04810
gene id: 1811193:A0O21_RS04810
uniprot id: A0A172Q7H7
names: Similarity
messages: Belongs to the ribF family.

1811193:A0O21 RS06140
gene id: 1811193:A0O21_RS06140
uniprot id: A0A172Q864
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS03305
gene id: 1811193:A0O21_RS03305
uniprot id: A0A172Q6Q1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1811193:A0O21 RS01430
gene id: 1811193:A0O21_RS01430
uniprot id: A0A172Q5P4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1811193:A0O21 RS10505
gene id: 1811193:A0O21_RS10505
uniprot id: A0A172QAC0
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS09505
gene id: 1811193:A0O21_RS09505
uniprot id: A0A172Q9S8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1811193:A0O21 RS06450
gene id: 1811193:A0O21_RS06450
uniprot id: A0A172Q877
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1811193:A0O21 RS05930
gene id: 1811193:A0O21_RS05930
uniprot id: A0A172Q866
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1811193:A0O21 RS01860
gene id: 1811193:A0O21_RS01860
uniprot id: A0A172Q5W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS05910
gene id: 1811193:A0O21_RS05910
uniprot id: A0A172Q818
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1811193:A0O21 RS00965
gene id: 1811193:A0O21_RS00965
uniprot id: A0A172Q5H3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1811193:A0O21 RS08620
gene id: 1811193:A0O21_RS08620
uniprot id: A0A172QAN1
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1811193:A0O21 RS08835
gene id: 1811193:A0O21_RS08835
uniprot id: A0A172Q9K1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS09540
gene id: 1811193:A0O21_RS09540
uniprot id: A0A172Q9U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1811193:A0O21 RS05460
gene id: 1811193:A0O21_RS05460
uniprot id: A0A172Q7T3
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS05590
gene id: 1811193:A0O21_RS05590
uniprot id: A0A172Q7Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1811193:A0O21 RS05600
gene id: 1811193:A0O21_RS05600
uniprot id: A0A172Q7S3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: Belongs to the CRISPR-associated protein Cas9 family. Subtype II-A subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

1811193:A0O21 RS09490
gene id: 1811193:A0O21_RS09490
uniprot id: A0A172Q9T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1811193:A0O21 RS08150
gene id: 1811193:A0O21_RS08150
uniprot id: A0A172Q929
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1811193:A0O21 RS00915
gene id: 1811193:A0O21_RS00915
uniprot id: A0A172Q5G5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1811193:A0O21 RS03070
gene id: 1811193:A0O21_RS03070
uniprot id: A0A172Q6P0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1811193:A0O21 RS01970
gene id: 1811193:A0O21_RS01970
uniprot id: A0A172QAE3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1811193:A0O21 RS06935
gene id: 1811193:A0O21_RS06935
uniprot id: A0A172QAL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS02025
gene id: 1811193:A0O21_RS02025
uniprot id: A0A172Q620
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1811193:A0O21 RS07165
gene id: 1811193:A0O21_RS07165
uniprot id: A0A172Q8R2
names: Similarity
messages: Belongs to the IMPACT family.

1811193:A0O21 RS09555
gene id: 1811193:A0O21_RS09555
uniprot id: A0A172Q9U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1811193:A0O21 RS03145
gene id: 1811193:A0O21_RS03145
uniprot id: A0A172Q6M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1811193:A0O21 RS03905
gene id: 1811193:A0O21_RS03905
uniprot id: A0A172Q6Z4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1811193:A0O21 RS06805
gene id: 1811193:A0O21_RS06805
uniprot id: A0A172Q8N3
names: Similarity
messages: Belongs to the TrpF family.

1811193:A0O21 RS07305
gene id: 1811193:A0O21_RS07305
uniprot id: A0A172Q8L1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1811193:A0O21 RS06075
gene id: 1811193:A0O21_RS06075
uniprot id: A0A172Q806
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

1811193:A0O21 RS10425
gene id: 1811193:A0O21_RS10425
uniprot id: A0A172QA17
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1811193:A0O21 RS06825
gene id: 1811193:A0O21_RS06825
uniprot id: A0A172QAI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1811193:A0O21 RS08735
gene id: 1811193:A0O21_RS08735
uniprot id: A0A172Q9B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1811193:A0O21 RS03140
gene id: 1811193:A0O21_RS03140
uniprot id: A0A172Q6L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1811193:A0O21 RS00780
gene id: 1811193:A0O21_RS00780
uniprot id: A0A172Q5D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1811193:A0O21 RS05075
gene id: 1811193:A0O21_RS05075
uniprot id: A0A172Q7J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1811193:A0O21 RS09220
gene id: 1811193:A0O21_RS09220
uniprot id: A0A172Q9M7
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS07885
gene id: 1811193:A0O21_RS07885
uniprot id: A0A172Q902
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1811193:A0O21 RS04250
gene id: 1811193:A0O21_RS04250
uniprot id: A0A172Q756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1811193:A0O21 RS02945
gene id: 1811193:A0O21_RS02945
uniprot id: A0A172Q6D1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1811193:A0O21 RS07225
gene id: 1811193:A0O21_RS07225
uniprot id: A0A172Q8Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1811193:A0O21 RS04925
gene id: 1811193:A0O21_RS04925
uniprot id: A0A172Q7J6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1811193:A0O21 RS07730
gene id: 1811193:A0O21_RS07730
uniprot id: A0A172Q8Z3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1811193:A0O21 RS00220
gene id: 1811193:A0O21_RS00220
uniprot id: A0A172Q531
names: Similarity
messages: Belongs to the acylphosphatase family.

1811193:A0O21 RS05380
gene id: 1811193:A0O21_RS05380
uniprot id: A0A172Q7S4
names: Similarity
messages: Belongs to the thioredoxin family.

1811193:A0O21 RS02180
gene id: 1811193:A0O21_RS02180
uniprot id: A0A172Q632
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1811193:A0O21 RS04300
gene id: 1811193:A0O21_RS04300
uniprot id: A0A172Q766
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS04680
gene id: 1811193:A0O21_RS04680
uniprot id: A0A172Q7F0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1811193:A0O21 RS06405
gene id: 1811193:A0O21_RS06405
uniprot id: A0A172Q8A3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS07625
gene id: 1811193:A0O21_RS07625
uniprot id: A0A172QAF3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1811193:A0O21 RS06925
gene id: 1811193:A0O21_RS06925
uniprot id: A0A172Q8L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1811193:A0O21 RS01730
gene id: 1811193:A0O21_RS01730
uniprot id: A0A172Q5Y0
names: Similarity
messages: Belongs to the leucine-binding protein family.

1811193:A0O21 RS07975
gene id: 1811193:A0O21_RS07975
uniprot id: A0A172Q923
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1811193:A0O21 RS06205
gene id: 1811193:A0O21_RS06205
uniprot id: A0A172Q891
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1811193:A0O21 RS04335
gene id: 1811193:A0O21_RS04335
uniprot id: A0A172Q798
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1811193:A0O21 RS07235
gene id: 1811193:A0O21_RS07235
uniprot id: A0A172Q8N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1811193:A0O21 RS04935
gene id: 1811193:A0O21_RS04935
uniprot id: A0A172QAK2
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS06795
gene id: 1811193:A0O21_RS06795
uniprot id: A0A172Q8D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1811193:A0O21 RS07370
gene id: 1811193:A0O21_RS07370
uniprot id: A0A172Q8Y1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1811193:A0O21 RS00540
gene id: 1811193:A0O21_RS00540
uniprot id: A0A172Q578
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1811193:A0O21 RS09545
gene id: 1811193:A0O21_RS09545
uniprot id: A0A172Q9W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1811193:A0O21 RS09640
gene id: 1811193:A0O21_RS09640
uniprot id: A0A172Q9Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1811193:A0O21 RS07195
gene id: 1811193:A0O21_RS07195
uniprot id: A0A172Q8J0
names: Subcellular Location Annotation
messages: Cell membrane

1811193:A0O21 RS05205
gene id: 1811193:A0O21_RS05205
uniprot id: A0A172Q7S1
names: Function
names: Similarity
messages: Belongs to the CpsD/CapB family.
messages: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide.

1811193:A0O21 RS00340
gene id: 1811193:A0O21_RS00340
uniprot id: A0A172Q546
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS00400
gene id: 1811193:A0O21_RS00400
uniprot id: A0A172Q5B7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS06035
gene id: 1811193:A0O21_RS06035
uniprot id: A0A172Q841
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1811193:A0O21 RS07685
gene id: 1811193:A0O21_RS07685
uniprot id: A0A172Q8S1
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.

1811193:A0O21 RS02845
gene id: 1811193:A0O21_RS02845
uniprot id: A0A172Q6L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1811193:A0O21 RS05250
gene id: 1811193:A0O21_RS05250
uniprot id: A0A172QAF4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS05735
gene id: 1811193:A0O21_RS05735
uniprot id: A0A172Q7Y9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1811193:A0O21 RS08500
gene id: 1811193:A0O21_RS08500
uniprot id: A0A172Q9C9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS09520
gene id: 1811193:A0O21_RS09520
uniprot id: A0A172Q9W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1811193:A0O21 RS06025
gene id: 1811193:A0O21_RS06025
uniprot id: A0A172Q7Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS06690
gene id: 1811193:A0O21_RS06690
uniprot id: A0A172Q8A5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1811193:A0O21 RS00550
gene id: 1811193:A0O21_RS00550
uniprot id: A0A172Q573
names: Similarity
messages: Belongs to the aldolase LacD family.

1811193:A0O21 RS06745
gene id: 1811193:A0O21_RS06745
uniprot id: A0A172Q8B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS07410
gene id: 1811193:A0O21_RS07410
uniprot id: A0A172Q8N1
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS04485
gene id: 1811193:A0O21_RS04485
uniprot id: A0A172Q7A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1811193:A0O21 RS07920
gene id: 1811193:A0O21_RS07920
uniprot id: A0A172Q8Z4
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1811193:A0O21 RS04725
gene id: 1811193:A0O21_RS04725
uniprot id: A0A172Q7E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1811193:A0O21 RS04735
gene id: 1811193:A0O21_RS04735
uniprot id: A0A172Q7F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1811193:A0O21 RS07455
gene id: 1811193:A0O21_RS07455
uniprot id: A0A172Q8V3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1811193:A0O21 RS03050
gene id: 1811193:A0O21_RS03050
uniprot id: A0A172Q6F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS05195
gene id: 1811193:A0O21_RS05195
uniprot id: A0A172Q7T7
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS05815
gene id: 1811193:A0O21_RS05815
uniprot id: A0A172Q825
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1811193:A0O21 RS02940
gene id: 1811193:A0O21_RS02940
uniprot id: A0A172Q6L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1811193:A0O21 RS07890
gene id: 1811193:A0O21_RS07890
uniprot id: A0A172QAJ1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1811193:A0O21 RS00285
gene id: 1811193:A0O21_RS00285
uniprot id: A0A172Q540
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1811193:A0O21 RS05170
gene id: 1811193:A0O21_RS05170
uniprot id: A0A172Q7N1
names: Similarity
messages: Belongs to the stealth family.

1811193:A0O21 RS09690
gene id: 1811193:A0O21_RS09690
uniprot id: A0A172QA02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1811193:A0O21 RS02750
gene id: 1811193:A0O21_RS02750
uniprot id: A0A172Q6I3
names: Similarity
messages: Belongs to the FemABX family.

1811193:A0O21 RS06945
gene id: 1811193:A0O21_RS06945
uniprot id: A0A172Q8L0
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS09335
gene id: 1811193:A0O21_RS09335
uniprot id: A0A172Q9J8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1811193:A0O21 RS10390
gene id: 1811193:A0O21_RS10390
uniprot id: A0A172QA58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1811193:A0O21 RS05085
gene id: 1811193:A0O21_RS05085
uniprot id: A0A172Q7L1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1811193:A0O21 RS01120
gene id: 1811193:A0O21_RS01120
uniprot id: A0A172Q5I5
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS06850
gene id: 1811193:A0O21_RS06850
uniprot id: A0A172Q8D6
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS02320
gene id: 1811193:A0O21_RS02320
uniprot id: A0A172Q656
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1811193:A0O21 RS01995
gene id: 1811193:A0O21_RS01995
uniprot id: A0A172Q655
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS07840
gene id: 1811193:A0O21_RS07840
uniprot id: A0A172Q908
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS00205
gene id: 1811193:A0O21_RS00205
uniprot id: A0A172Q535
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1811193:A0O21 RS00650
gene id: 1811193:A0O21_RS00650
uniprot id: A0A172Q592
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1811193:A0O21 RS05305
gene id: 1811193:A0O21_RS05305
uniprot id: A0A172Q7Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0213 family.
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1811193:A0O21 RS07970
gene id: 1811193:A0O21_RS07970
uniprot id: A0A172Q910
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1811193:A0O21 RS07750
gene id: 1811193:A0O21_RS07750
uniprot id: A0A172Q8X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1811193:A0O21 RS03790
gene id: 1811193:A0O21_RS03790
uniprot id: A0A172Q723
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1811193:A0O21 RS02965
gene id: 1811193:A0O21_RS02965
uniprot id: A0A172Q6L6
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS01075
gene id: 1811193:A0O21_RS01075
uniprot id: A0A172Q5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1811193:A0O21 RS03530
gene id: 1811193:A0O21_RS03530
uniprot id: A0A172Q6N4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1811193:A0O21 RS08600
gene id: 1811193:A0O21_RS08600
uniprot id: A0A172Q9F0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1811193:A0O21 RS10515
gene id: 1811193:A0O21_RS10515
uniprot id: A0A172QA94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1811193:A0O21 RS06610
gene id: 1811193:A0O21_RS06610
uniprot id: A0A172Q8B0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1811193:A0O21 RS07430
gene id: 1811193:A0O21_RS07430
uniprot id: A0A172Q8V8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS08890
gene id: 1811193:A0O21_RS08890
uniprot id: A0A172Q9L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1811193:A0O21 RS00985
gene id: 1811193:A0O21_RS00985
uniprot id: A0A172Q5M4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1811193:A0O21 RS00250
gene id: 1811193:A0O21_RS00250
uniprot id: A0A172Q532
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1811193:A0O21 RS03500
gene id: 1811193:A0O21_RS03500
uniprot id: A0A172Q6W5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1811193:A0O21 RS08020
gene id: 1811193:A0O21_RS08020
uniprot id: A0A172Q921
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1811193:A0O21 RS00805
gene id: 1811193:A0O21_RS00805
uniprot id: A0A172Q5D7
names: Similarity
messages: Belongs to the peptidase M24B family.

1811193:A0O21 RS04800
gene id: 1811193:A0O21_RS04800
uniprot id: A0A172Q7F8
names: Similarity
messages: Belongs to the UPF0223 family.

1811193:A0O21 RS10480
gene id: 1811193:A0O21_RS10480
uniprot id: A0A172QA77
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS06770
gene id: 1811193:A0O21_RS06770
uniprot id: A0A172Q8I1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1811193:A0O21 RS02720
gene id: 1811193:A0O21_RS02720
uniprot id: A0A172Q6D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1811193:A0O21 RS07925
gene id: 1811193:A0O21_RS07925
uniprot id: A0A172Q936
names: Similarity
names: Subunit
messages: Belongs to the UPF0237 family.
messages: Homodimer.

1811193:A0O21 RS08200
gene id: 1811193:A0O21_RS08200
uniprot id: A0A172Q904
names: Function
names: Similarity
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

1811193:A0O21 RS09515
gene id: 1811193:A0O21_RS09515
uniprot id: A0A172Q9S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1811193:A0O21 RS06065
gene id: 1811193:A0O21_RS06065
uniprot id: A0A172Q865
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1811193:A0O21 RS03125
gene id: 1811193:A0O21_RS03125
uniprot id: A0A172Q6P8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1811193:A0O21 RS00370
gene id: 1811193:A0O21_RS00370
uniprot id: A0A172Q558
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1811193:A0O21 RS10345
gene id: 1811193:A0O21_RS10345
uniprot id: A0A172QA91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1811193:A0O21 RS09390
gene id: 1811193:A0O21_RS09390
uniprot id: A0A172Q9R0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1811193:A0O21 RS06415
gene id: 1811193:A0O21_RS06415
uniprot id: A0A172Q8C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1811193:A0O21 RS03535
gene id: 1811193:A0O21_RS03535
uniprot id: A0A172Q6S2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1811193:A0O21 RS08320
gene id: 1811193:A0O21_RS08320
uniprot id: A0A172Q966
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1811193:A0O21 RS04595
gene id: 1811193:A0O21_RS04595
uniprot id: A0A172Q793
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS06145
gene id: 1811193:A0O21_RS06145
uniprot id: A0A172Q882
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1811193:A0O21 RS05595
gene id: 1811193:A0O21_RS05595
uniprot id: A0A172Q7W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1811193:A0O21 RS04895
gene id: 1811193:A0O21_RS04895
uniprot id: A0A172Q7H5
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS08630
gene id: 1811193:A0O21_RS08630
uniprot id: A0A172Q984
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1811193:A0O21 RS06705
gene id: 1811193:A0O21_RS06705
uniprot id: A0A172Q8E6
names: Subcellular Location Annotation
messages: Cytoplasm

1811193:A0O21 RS09870
gene id: 1811193:A0O21_RS09870
uniprot id: A0A172QA01
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1811193:A0O21 RS08025
gene id: 1811193:A0O21_RS08025
uniprot id: A0A172Q931
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1811193:A0O21 RS07660
gene id: 1811193:A0O21_RS07660
uniprot id: A0A172Q8Y0
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS02455
gene id: 1811193:A0O21_RS02455
uniprot id: A0A172Q653
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS03735
gene id: 1811193:A0O21_RS03735
uniprot id: A0A172Q713
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1811193:A0O21 RS09720
gene id: 1811193:A0O21_RS09720
uniprot id: A0A172Q9W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1811193:A0O21 RS02250
gene id: 1811193:A0O21_RS02250
uniprot id: A0A172QA87
names: Similarity
messages: Belongs to the UPF0346 family.

1811193:A0O21 RS01285
gene id: 1811193:A0O21_RS01285
uniprot id: A0A172Q5K9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1811193:A0O21 RS05675
gene id: 1811193:A0O21_RS05675
uniprot id: A0A172Q804
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1811193:A0O21 RS06275
gene id: 1811193:A0O21_RS06275
uniprot id: A0A172Q8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

1811193:A0O21 RS09425
gene id: 1811193:A0O21_RS09425
uniprot id: A0A172Q9S5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1811193:A0O21 RS04395
gene id: 1811193:A0O21_RS04395
uniprot id: A0A172Q7A4
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS07580
gene id: 1811193:A0O21_RS07580
uniprot id: A0A172Q8S7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1811193:A0O21 RS09475
gene id: 1811193:A0O21_RS09475
uniprot id: A0A172Q9P8
names: Similarity
messages: Belongs to the peptidase S66 family.

1811193:A0O21 RS02465
gene id: 1811193:A0O21_RS02465
uniprot id: A0A172Q651
names: Similarity
messages: Belongs to the peptidase M24B family.

1811193:A0O21 RS05100
gene id: 1811193:A0O21_RS05100
uniprot id: A0A172Q7I1
names: Similarity
messages: Belongs to the acetyltransferase family.

1811193:A0O21 RS04415
gene id: 1811193:A0O21_RS04415
uniprot id: A0A172Q7E4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1811193:A0O21 RS01740
gene id: 1811193:A0O21_RS01740
uniprot id: A0A172Q5W6
names: Subcellular Location Annotation
messages: Membrane

1811193:A0O21 RS00180
gene id: 1811193:A0O21_RS00180
uniprot id: A0A172Q517
names: Similarity
messages: Belongs to the WXG100 family.

1811193:A0O21 RS01100
gene id: 1811193:A0O21_RS01100
uniprot id: A0A172Q5M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0397 family.
messages: Cell membrane

1811193:A0O21 RS02675
gene id: 1811193:A0O21_RS02675
uniprot id: A0A172Q6G4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1811193:A0O21 RS09165
gene id: 1811193:A0O21_RS09165
uniprot id: A0A172QAJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1811193:A0O21 RS07385
gene id: 1811193:A0O21_RS07385
uniprot id: A0A172Q8T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS06665
gene id: 1811193:A0O21_RS06665
uniprot id: A0A172Q8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1811193:A0O21 RS08265
gene id: 1811193:A0O21_RS08265
uniprot id: A0A172Q961
names: Similarity
messages: Belongs to the XFP family.

1811193:A0O21 RS08640
gene id: 1811193:A0O21_RS08640
uniprot id: A0A172Q9J2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1811193:A0O21 RS07295
gene id: 1811193:A0O21_RS07295
uniprot id: A0A172Q8Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1811193:A0O21 RS02515
gene id: 1811193:A0O21_RS02515
uniprot id: A0A172Q661
names: Subcellular Location Annotation
messages: Cell membrane