1805933:BV494 RS14985
gene id: 1805933:BV494_RS14985
uniprot id: A0A2L1UTK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1805933:BV494 RS00405
gene id: 1805933:BV494_RS00405
uniprot id: A0A2L1UKM1
names: Similarity
messages: Belongs to the P(II) protein family.

1805933:BV494 RS17255
gene id: 1805933:BV494_RS17255
uniprot id: A0A2L1UUC4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1805933:BV494 RS11830
gene id: 1805933:BV494_RS11830
uniprot id: A0A2L1URQ1
names: Similarity
messages: Belongs to the P(II) protein family.

1805933:BV494 RS02060
gene id: 1805933:BV494_RS02060
uniprot id: A0A2L1ULH5
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1805933:BV494 RS02695
gene id: 1805933:BV494_RS02695
uniprot id: A0A2L1ULU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1805933:BV494 RS15005
gene id: 1805933:BV494_RS15005
uniprot id: A0A2L1UT58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1805933:BV494 RS15050
gene id: 1805933:BV494_RS15050
uniprot id: A0A2L1UT89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1805933:BV494 RS03640
gene id: 1805933:BV494_RS03640
uniprot id: A0A2L1UMB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1805933:BV494 RS00795
gene id: 1805933:BV494_RS00795
uniprot id: A0A2L1UKV3
names: Subcellular Location Annotation
messages: Cytoplasm

1805933:BV494 RS19200
gene id: 1805933:BV494_RS19200
uniprot id: A0A2L1UVI0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1805933:BV494 RS14745
gene id: 1805933:BV494_RS14745
uniprot id: A0A2L1UT23
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1805933:BV494 RS14570
gene id: 1805933:BV494_RS14570
uniprot id: A0A2L1UT16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1805933:BV494 RS15060
gene id: 1805933:BV494_RS15060
uniprot id: A0A2L1UT78
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1805933:BV494 RS01680
gene id: 1805933:BV494_RS01680
uniprot id: A0A2L1ULJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1805933:BV494 RS19955
gene id: 1805933:BV494_RS19955
uniprot id: A0A2L1UVU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1805933:BV494 RS09790
gene id: 1805933:BV494_RS09790
uniprot id: A0A2L1UQH5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1805933:BV494 RS15090
gene id: 1805933:BV494_RS15090
uniprot id: A0A2L1UT86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1805933:BV494 RS15140
gene id: 1805933:BV494_RS15140
uniprot id: A0A2L1UTN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1805933:BV494 RS08995
gene id: 1805933:BV494_RS08995
uniprot id: A0A2L1UQ47
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1805933:BV494 RS19180
gene id: 1805933:BV494_RS19180
uniprot id: A0A2L1UVK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

1805933:BV494 RS16710
gene id: 1805933:BV494_RS16710
uniprot id: A0A2L1UU64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1805933:BV494 RS17460
gene id: 1805933:BV494_RS17460
uniprot id: A0A2L1UUK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

1805933:BV494 RS15040
gene id: 1805933:BV494_RS15040
uniprot id: A0A2L1UT76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1805933:BV494 RS07025
gene id: 1805933:BV494_RS07025
uniprot id: A0A2L1UP31
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1805933:BV494 RS11440
gene id: 1805933:BV494_RS11440
uniprot id: A0A2L1URT3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1805933:BV494 RS09765
gene id: 1805933:BV494_RS09765
uniprot id: A0A2L1UQJ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1805933:BV494 RS12625
gene id: 1805933:BV494_RS12625
uniprot id: A0A2L1URZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1805933:BV494 RS09005
gene id: 1805933:BV494_RS09005
uniprot id: A0A2L1UQ46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1805933:BV494 RS13935
gene id: 1805933:BV494_RS13935
uniprot id: A0A2L1UST2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

1805933:BV494 RS14750
gene id: 1805933:BV494_RS14750
uniprot id: A0A2L1UX99
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1805933:BV494 RS21400
gene id: 1805933:BV494_RS21400
uniprot id: A0A2L1UWP3
names: Similarity
messages: Belongs to the UPF0253 family.

1805933:BV494 RS16840
gene id: 1805933:BV494_RS16840
uniprot id: A0A2L1UUB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1805933:BV494 RS02180
gene id: 1805933:BV494_RS02180
uniprot id: A0A2L1ULJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

1805933:BV494 RS21270
gene id: 1805933:BV494_RS21270
uniprot id: A0A2L1UWQ3
names: Similarity
messages: Belongs to the UPF0325 family.

1805933:BV494 RS17505
gene id: 1805933:BV494_RS17505
uniprot id: A0A2L1UUJ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

1805933:BV494 RS20340
gene id: 1805933:BV494_RS20340
uniprot id: A0A2L1UW55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1805933:BV494 RS18380
gene id: 1805933:BV494_RS18380
uniprot id: A0A2L1UUX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1805933:BV494 RS13460
gene id: 1805933:BV494_RS13460
uniprot id: A0A2L1USJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1805933:BV494 RS03665
gene id: 1805933:BV494_RS03665
uniprot id: A0A2L1UMC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1805933:BV494 RS17070
gene id: 1805933:BV494_RS17070
uniprot id: A0A2L1UUF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1805933:BV494 RS18935
gene id: 1805933:BV494_RS18935
uniprot id: A0A2L1UVJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1805933:BV494 RS09770
gene id: 1805933:BV494_RS09770
uniprot id: A0A2L1UQH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1805933:BV494 RS11885
gene id: 1805933:BV494_RS11885
uniprot id: A0A2L1URZ1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1805933:BV494 RS14580
gene id: 1805933:BV494_RS14580
uniprot id: A0A2L1USZ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1805933:BV494 RS15080
gene id: 1805933:BV494_RS15080
uniprot id: A0A2L1UTD7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1805933:BV494 RS16715
gene id: 1805933:BV494_RS16715
uniprot id: A0A2L1UU19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1805933:BV494 RS12305
gene id: 1805933:BV494_RS12305
uniprot id: A0A2L1URZ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1805933:BV494 RS08305
gene id: 1805933:BV494_RS08305
uniprot id: A0A2L1UQ21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1805933:BV494 RS17260
gene id: 1805933:BV494_RS17260
uniprot id: A0A2L1UUM7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1805933:BV494 RS14440
gene id: 1805933:BV494_RS14440
uniprot id: A0A2L1UT36
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1805933:BV494 RS02880
gene id: 1805933:BV494_RS02880
uniprot id: A0A2L1UM85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1805933:BV494 RS15035
gene id: 1805933:BV494_RS15035
uniprot id: A0A2L1UTL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1805933:BV494 RS08980
gene id: 1805933:BV494_RS08980
uniprot id: A0A2L1UQ32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1805933:BV494 RS14995
gene id: 1805933:BV494_RS14995
uniprot id: A0A2L1UT79
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1805933:BV494 RS09580
gene id: 1805933:BV494_RS09580
uniprot id: A0A2L1UQE3
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1805933:BV494 RS00905
gene id: 1805933:BV494_RS00905
uniprot id: A0A2L1UKV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1805933:BV494 RS19160
gene id: 1805933:BV494_RS19160
uniprot id: A0A2L1UVG5
names: Similarity
messages: Belongs to the BolA/IbaG family.

1805933:BV494 RS19195
gene id: 1805933:BV494_RS19195
uniprot id: A0A2L1UVB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1805933:BV494 RS15055
gene id: 1805933:BV494_RS15055
uniprot id: A0A2L1UT67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1805933:BV494 RS20415
gene id: 1805933:BV494_RS20415
uniprot id: A0A2L1UW20
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1805933:BV494 RS15075
gene id: 1805933:BV494_RS15075
uniprot id: A0A2L1UT73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1805933:BV494 RS15095
gene id: 1805933:BV494_RS15095
uniprot id: A0A2L1UT97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1805933:BV494 RS18870
gene id: 1805933:BV494_RS18870
uniprot id: A0A2L1UV62
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

1805933:BV494 RS11785
gene id: 1805933:BV494_RS11785
uniprot id: A0A2L1UX70
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

1805933:BV494 RS17745
gene id: 1805933:BV494_RS17745
uniprot id: A0A2L1UUN2
names: Similarity
messages: Belongs to the thioredoxin family.

1805933:BV494 RS04230
gene id: 1805933:BV494_RS04230
uniprot id: A0A2L1UMM6
names: Subcellular Location Annotation
messages: Cytoplasm

1805933:BV494 RS02555
gene id: 1805933:BV494_RS02555
uniprot id: A0A2L1UM21
names: Subcellular Location Annotation
messages: Cytoplasm

1805933:BV494 RS11945
gene id: 1805933:BV494_RS11945
uniprot id: A0A2L1URK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1805933:BV494 RS15000
gene id: 1805933:BV494_RS15000
uniprot id: A0A2L1UT80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1805933:BV494 RS17375
gene id: 1805933:BV494_RS17375
uniprot id: A0A2L1UUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1805933:BV494 RS17480
gene id: 1805933:BV494_RS17480
uniprot id: A0A2L1UUJ0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1805933:BV494 RS14340
gene id: 1805933:BV494_RS14340
uniprot id: A0A2L1UT01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1805933:BV494 RS02500
gene id: 1805933:BV494_RS02500
uniprot id: A0A2L1UM10
names: Similarity
messages: Belongs to the UPF0145 family.

1805933:BV494 RS00060
gene id: 1805933:BV494_RS00060
uniprot id: A0A2L1UKQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

1805933:BV494 RS15145
gene id: 1805933:BV494_RS15145
uniprot id: A0A2L1UT95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1805933:BV494 RS18450
gene id: 1805933:BV494_RS18450
uniprot id: A0A2L1UUZ5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1805933:BV494 RS15020
gene id: 1805933:BV494_RS15020
uniprot id: A0A2L1UT75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1805933:BV494 RS15105
gene id: 1805933:BV494_RS15105
uniprot id: A0A2L1UT77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1805933:BV494 RS15100
gene id: 1805933:BV494_RS15100
uniprot id: A0A2L1UTA5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1805933:BV494 RS12655
gene id: 1805933:BV494_RS12655
uniprot id: A0A2L1URY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

1805933:BV494 RS02570
gene id: 1805933:BV494_RS02570
uniprot id: A0A2L1ULR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1805933:BV494 RS12070
gene id: 1805933:BV494_RS12070
uniprot id: A0A2L1URN2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1805933:BV494 RS18910
gene id: 1805933:BV494_RS18910
uniprot id: A0A2L1UVF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1805933:BV494 RS14975
gene id: 1805933:BV494_RS14975
uniprot id: A0A2L1UT54
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1805933:BV494 RS01640
gene id: 1805933:BV494_RS01640
uniprot id: A0A2L1ULB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1805933:BV494 RS11190
gene id: 1805933:BV494_RS11190
uniprot id: A0A2L1UR81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1805933:BV494 RS10830
gene id: 1805933:BV494_RS10830
uniprot id: A0A2L1UR33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1805933:BV494 RS14990
gene id: 1805933:BV494_RS14990
uniprot id: A0A2L1UT65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1805933:BV494 RS14970
gene id: 1805933:BV494_RS14970
uniprot id: A0A2L1UT66
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1805933:BV494 RS15045
gene id: 1805933:BV494_RS15045
uniprot id: A0A2L1UT85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1805933:BV494 RS06585
gene id: 1805933:BV494_RS06585
uniprot id: A0A2L1UNV8
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

1805933:BV494 RS04995
gene id: 1805933:BV494_RS04995
uniprot id: A0A2L1UN15
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

1805933:BV494 RS14350
gene id: 1805933:BV494_RS14350
uniprot id: A0A2L1USU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1805933:BV494 RS18355
gene id: 1805933:BV494_RS18355
uniprot id: A0A2L1UV09
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1805933:BV494 RS10520
gene id: 1805933:BV494_RS10520
uniprot id: A0A2L1UQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1805933:BV494 RS12110
gene id: 1805933:BV494_RS12110
uniprot id: A0A2L1US30
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1805933:BV494 RS09490
gene id: 1805933:BV494_RS09490
uniprot id: A0A2L1UQD2
names: Subcellular Location Annotation
messages: Cytoplasm

1805933:BV494 RS13835
gene id: 1805933:BV494_RS13835
uniprot id: A0A2L1USQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.