1796646:A4V02 RS13020
gene id: 1796646:A4V02_RS13020
uniprot id: A0A1B1SCJ3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1796646:A4V02 RS12290
gene id: 1796646:A4V02_RS12290
uniprot id: A0A1B1SC87
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1796646:A4V02 RS11475
gene id: 1796646:A4V02_RS11475
uniprot id: A0A1B1SBT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1796646:A4V02 RS09610
gene id: 1796646:A4V02_RS09610
uniprot id: A0A1B1SAV7
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

1796646:A4V02 RS01480
gene id: 1796646:A4V02_RS01480
uniprot id: A0A1B1S6W7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1796646:A4V02 RS03055
gene id: 1796646:A4V02_RS03055
uniprot id: A0A1B1S7M0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1796646:A4V02 RS11320
gene id: 1796646:A4V02_RS11320
uniprot id: A0A1B1SBQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1796646:A4V02 RS10990
gene id: 1796646:A4V02_RS10990
uniprot id: A0A1B1SBF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1796646:A4V02 RS09405
gene id: 1796646:A4V02_RS09405
uniprot id: A0A1B1SAT8
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1796646:A4V02 RS01850
gene id: 1796646:A4V02_RS01850
uniprot id: A0A1B1SCZ6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1796646:A4V02 RS07595
gene id: 1796646:A4V02_RS07595
uniprot id: A0A1B1S9V4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1796646:A4V02 RS09720
gene id: 1796646:A4V02_RS09720
uniprot id: A0A1B1SAX4
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS10930
gene id: 1796646:A4V02_RS10930
uniprot id: A0A1B1SBK5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1796646:A4V02 RS11530
gene id: 1796646:A4V02_RS11530
uniprot id: A0A1B1SBU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1796646:A4V02 RS11100
gene id: 1796646:A4V02_RS11100
uniprot id: A0A1B1SBG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1796646:A4V02 RS08595
gene id: 1796646:A4V02_RS08595
uniprot id: A0A1B1SAE5
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1796646:A4V02 RS03460
gene id: 1796646:A4V02_RS03460
uniprot id: A0A1B1S7T6
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1796646:A4V02 RS09410
gene id: 1796646:A4V02_RS09410
uniprot id: A0A1B1SAS1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1796646:A4V02 RS00795
gene id: 1796646:A4V02_RS00795
uniprot id: A0A1B1SCX4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1796646:A4V02 RS02450
gene id: 1796646:A4V02_RS02450
uniprot id: A0A1B1S7B8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S16 family.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1796646:A4V02 RS09500
gene id: 1796646:A4V02_RS09500
uniprot id: A0A1B1SAT6
names: Similarity
messages: Belongs to the SufE family.

1796646:A4V02 RS08195
gene id: 1796646:A4V02_RS08195
uniprot id: A0A1B1SA67
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1796646:A4V02 RS01255
gene id: 1796646:A4V02_RS01255
uniprot id: A0A1B1SD39
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS11935
gene id: 1796646:A4V02_RS11935
uniprot id: A0A1B1SBX1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1796646:A4V02 RS03990
gene id: 1796646:A4V02_RS03990
uniprot id: A0A1B1S828
names: Similarity
messages: Belongs to the ParB family.

1796646:A4V02 RS00635
gene id: 1796646:A4V02_RS00635
uniprot id: A0A1B1S6I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1796646:A4V02 RS10545
gene id: 1796646:A4V02_RS10545
uniprot id: A0A1B1SB96
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1796646:A4V02 RS08850
gene id: 1796646:A4V02_RS08850
uniprot id: A0A1B1SAH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1796646:A4V02 RS12865
gene id: 1796646:A4V02_RS12865
uniprot id: A0A1B1SCF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1796646:A4V02 RS13180
gene id: 1796646:A4V02_RS13180
uniprot id: A0A1B1SCL9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796646:A4V02 RS00570
gene id: 1796646:A4V02_RS00570
uniprot id: A0A1B1S6H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS09320
gene id: 1796646:A4V02_RS09320
uniprot id: A0A1B1SAR1
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

1796646:A4V02 RS02740
gene id: 1796646:A4V02_RS02740
uniprot id: A0A1B1S7H1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1796646:A4V02 RS02935
gene id: 1796646:A4V02_RS02935
uniprot id: A0A1B1S7J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1796646:A4V02 RS06700
gene id: 1796646:A4V02_RS06700
uniprot id: A0A1B1S9E4
names: Similarity
messages: Belongs to the RutC family.

1796646:A4V02 RS02265
gene id: 1796646:A4V02_RS02265
uniprot id: A0A1B1S796
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1796646:A4V02 RS12465
gene id: 1796646:A4V02_RS12465
uniprot id: A0A1B1SDS5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1796646:A4V02 RS13680
gene id: 1796646:A4V02_RS13680
uniprot id: A0A1B1SCV1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1796646:A4V02 RS12995
gene id: 1796646:A4V02_RS12995
uniprot id: A0A1B1SCJ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1796646:A4V02 RS13040
gene id: 1796646:A4V02_RS13040
uniprot id: A0A1B1SCM2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1796646:A4V02 RS01415
gene id: 1796646:A4V02_RS01415
uniprot id: A0A1B1S6U6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1796646:A4V02 RS05930
gene id: 1796646:A4V02_RS05930
uniprot id: A0A1B1S929
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1796646:A4V02 RS10975
gene id: 1796646:A4V02_RS10975
uniprot id: A0A1B1SBJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1796646:A4V02 RS05000
gene id: 1796646:A4V02_RS05000
uniprot id: A0A1B1S8K2
names: Similarity
messages: Belongs to the glycosyltransferase 6 family.

1796646:A4V02 RS01355
gene id: 1796646:A4V02_RS01355
uniprot id: A0A1B1S6U2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1796646:A4V02 RS03455
gene id: 1796646:A4V02_RS03455
uniprot id: A0A1B1S7T7
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1796646:A4V02 RS12230
gene id: 1796646:A4V02_RS12230
uniprot id: A0A1B1SC78
names: Similarity
messages: Belongs to the LOG family.

1796646:A4V02 RS02795
gene id: 1796646:A4V02_RS02795
uniprot id: A0A1B1S7I1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1796646:A4V02 RS12250
gene id: 1796646:A4V02_RS12250
uniprot id: A0A1B1SC79
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1796646:A4V02 RS10115
gene id: 1796646:A4V02_RS10115
uniprot id: A0A1B1SB26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1796646:A4V02 RS04815
gene id: 1796646:A4V02_RS04815
uniprot id: A0A1B1S8F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1796646:A4V02 RS09280
gene id: 1796646:A4V02_RS09280
uniprot id: A0A1B1SAQ3
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS07960
gene id: 1796646:A4V02_RS07960
uniprot id: A0A1B1SA25
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1796646:A4V02 RS04290
gene id: 1796646:A4V02_RS04290
uniprot id: A0A1B1S872
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1796646:A4V02 RS09475
gene id: 1796646:A4V02_RS09475
uniprot id: A0A1B1SAT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1796646:A4V02 RS01925
gene id: 1796646:A4V02_RS01925
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS12910
gene id: 1796646:A4V02_RS12910
uniprot id: A0A1B1SCF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1796646:A4V02 RS12360
gene id: 1796646:A4V02_RS12360
uniprot id: A0A1B1SCH8
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS06670
gene id: 1796646:A4V02_RS06670
uniprot id: A0A1B1S9E1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1796646:A4V02 RS04135
gene id: 1796646:A4V02_RS04135
uniprot id: A0A1B1S855
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1796646:A4V02 RS09400
gene id: 1796646:A4V02_RS09400
uniprot id: A0A1B1SAS9
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1796646:A4V02 RS08960
gene id: 1796646:A4V02_RS08960
uniprot id: A0A1B1SAK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1796646:A4V02 RS03110
gene id: 1796646:A4V02_RS03110
uniprot id: A0A1B1S7N1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1796646:A4V02 RS10070
gene id: 1796646:A4V02_RS10070
uniprot id: A0A1B1SB35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS08315
gene id: 1796646:A4V02_RS08315
uniprot id: A0A1B1SAA0
names: Similarity
messages: Belongs to the IMPACT family.

1796646:A4V02 RS00230
gene id: 1796646:A4V02_RS00230
uniprot id: A0A1B1S6B4
names: Similarity
messages: Belongs to the universal stress protein A family.

1796646:A4V02 RS03965
gene id: 1796646:A4V02_RS03965
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS04940
gene id: 1796646:A4V02_RS04940
uniprot id: A0A1B1S8K0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1796646:A4V02 RS00135
gene id: 1796646:A4V02_RS00135
uniprot id: A0A1B1S689
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1796646:A4V02 RS08970
gene id: 1796646:A4V02_RS08970
uniprot id: A0A1B1SAK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1796646:A4V02 RS06800
gene id: 1796646:A4V02_RS06800
uniprot id: A0A1B1S9G9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1796646:A4V02 RS07445
gene id: 1796646:A4V02_RS07445
uniprot id: A0A1B1S9U1
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS04715
gene id: 1796646:A4V02_RS04715
uniprot id: A0A1B1S8E4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1796646:A4V02 RS10850
gene id: 1796646:A4V02_RS10850
uniprot id: A0A1B1SBE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

1796646:A4V02 RS07780
gene id: 1796646:A4V02_RS07780
uniprot id: A0A1B1S9Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1796646:A4V02 RS04830
gene id: 1796646:A4V02_RS04830
uniprot id: A0A1B1SD32
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1796646:A4V02 RS09695
gene id: 1796646:A4V02_RS09695
uniprot id: A0A1B1SAW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796646:A4V02 RS04445
gene id: 1796646:A4V02_RS04445
uniprot id: A0A1B1S899
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1796646:A4V02 RS07640
gene id: 1796646:A4V02_RS07640
uniprot id: A0A1B1S9X0
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS09440
gene id: 1796646:A4V02_RS09440
uniprot id: A0A1B1SAS4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1796646:A4V02 RS02020
gene id: 1796646:A4V02_RS02020
uniprot id: A0A1B1S758
names: Similarity
messages: Belongs to the YciI family.

1796646:A4V02 RS07800
gene id: 1796646:A4V02_RS07800
uniprot id: A0A1B1SDC1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1796646:A4V02 RS10620
gene id: 1796646:A4V02_RS10620
uniprot id: A0A1B1SBA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1796646:A4V02 RS12870
gene id: 1796646:A4V02_RS12870
uniprot id: A0A1B1SCG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1796646:A4V02 RS06705
gene id: 1796646:A4V02_RS06705
uniprot id: A0A1B1S9F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1796646:A4V02 RS05160
gene id: 1796646:A4V02_RS05160
uniprot id: A0A1B1S8N2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1796646:A4V02 RS09075
gene id: 1796646:A4V02_RS09075
uniprot id: A0A1B1SAM3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1796646:A4V02 RS01695
gene id: 1796646:A4V02_RS01695
uniprot id: A0A1B1S6Z3
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS13340
gene id: 1796646:A4V02_RS13340
uniprot id: A0A1B1SCN3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796646:A4V02 RS11990
gene id: 1796646:A4V02_RS11990
uniprot id: A0A1B1SC38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1796646:A4V02 RS04210
gene id: 1796646:A4V02_RS04210
uniprot id: A0A1B1S852
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1796646:A4V02 RS09325
gene id: 1796646:A4V02_RS09325
uniprot id: A0A1B1SAQ8
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS01015
gene id: 1796646:A4V02_RS01015
uniprot id: A0A1B1S6N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1796646:A4V02 RS09670
gene id: 1796646:A4V02_RS09670
uniprot id: A0A1B1SAX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1796646:A4V02 RS09335
gene id: 1796646:A4V02_RS09335
uniprot id: A0A1B1SDA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796646:A4V02 RS12030
gene id: 1796646:A4V02_RS12030
uniprot id: A0A1B1SC03
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS04835
gene id: 1796646:A4V02_RS04835
uniprot id: A0A1B1S8G6
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1796646:A4V02 RS10210
gene id: 1796646:A4V02_RS10210
uniprot id: A0A1B1SB61
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1796646:A4V02 RS12925
gene id: 1796646:A4V02_RS12925
uniprot id: A0A1B1SCF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1796646:A4V02 RS09070
gene id: 1796646:A4V02_RS09070
uniprot id: A0A1B1SAK8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1796646:A4V02 RS07895
gene id: 1796646:A4V02_RS07895
uniprot id: A0A1B1SA17
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1796646:A4V02 RS09580
gene id: 1796646:A4V02_RS09580
uniprot id: A0A1B1SAU6
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS03130
gene id: 1796646:A4V02_RS03130
uniprot id: A0A1V0QE15
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1796646:A4V02 RS02850
gene id: 1796646:A4V02_RS02850
uniprot id: A0A1B1S7I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1796646:A4V02 RS09600
gene id: 1796646:A4V02_RS09600
uniprot id: A0A1B1SAW9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1796646:A4V02 RS04950
gene id: 1796646:A4V02_RS04950
uniprot id: A0A1B1S8I9
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1796646:A4V02 RS00465
gene id: 1796646:A4V02_RS00465
uniprot id: A0A1B1S6F2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1796646:A4V02 RS01530
gene id: 1796646:A4V02_RS01530
uniprot id: A0A1B1S6X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1796646:A4V02 RS05920
gene id: 1796646:A4V02_RS05920
uniprot id: A0A1B1S915
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS03390
gene id: 1796646:A4V02_RS03390
uniprot id: A0A1B1S7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1796646:A4V02 RS11615
gene id: 1796646:A4V02_RS11615
uniprot id: A0A1B1SBW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1796646:A4V02 RS12960
gene id: 1796646:A4V02_RS12960
uniprot id: A0A1B1SCG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1796646:A4V02 RS09980
gene id: 1796646:A4V02_RS09980
uniprot id: A0A1B1SB06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1796646:A4V02 RS05635
gene id: 1796646:A4V02_RS05635
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS00920
gene id: 1796646:A4V02_RS00920
uniprot id: A0A1B1S6M0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS04695
gene id: 1796646:A4V02_RS04695
uniprot id: A0A1B1SD39
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS08110
gene id: 1796646:A4V02_RS08110
uniprot id: A0A1B1SA54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1796646:A4V02 RS07415
gene id: 1796646:A4V02_RS07415
uniprot id: A0A1B1S9S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1796646:A4V02 RS04390
gene id: 1796646:A4V02_RS04390
uniprot id: A0A1B1S897
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS07660
gene id: 1796646:A4V02_RS07660
uniprot id: A0A1B1S9W9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1796646:A4V02 RS09735
gene id: 1796646:A4V02_RS09735
uniprot id: A0A1B1SAY3
names: Similarity
messages: Belongs to the peptidase S9C family.

1796646:A4V02 RS06140
gene id: 1796646:A4V02_RS06140
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS06030
gene id: 1796646:A4V02_RS06030
uniprot id: A0A1B1S948
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS02750
gene id: 1796646:A4V02_RS02750
uniprot id: A0A1B1S7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm

1796646:A4V02 RS09050
gene id: 1796646:A4V02_RS09050
uniprot id: A0A1B1SAL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1796646:A4V02 RS08510
gene id: 1796646:A4V02_RS08510
uniprot id: A0A1B1SAA4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1796646:A4V02 RS02595
gene id: 1796646:A4V02_RS02595
uniprot id: A0A1B1S7D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1796646:A4V02 RS09215
gene id: 1796646:A4V02_RS09215
uniprot id: A0A1B1SAN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796646:A4V02 RS13540
gene id: 1796646:A4V02_RS13540
uniprot id: A0A1B1SD84
names: Similarity
messages: Belongs to the Skp family.

1796646:A4V02 RS06905
gene id: 1796646:A4V02_RS06905
uniprot id: A0A1B1S9J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS02895
gene id: 1796646:A4V02_RS02895
uniprot id: A0A1B1S7J2
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS11400
gene id: 1796646:A4V02_RS11400
uniprot id: A0A1B1SBM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1796646:A4V02 RS12760
gene id: 1796646:A4V02_RS12760
uniprot id: A0A1B1SCD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1796646:A4V02 RS02990
gene id: 1796646:A4V02_RS02990
uniprot id: A0A1B1S7L0
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1796646:A4V02 RS11205
gene id: 1796646:A4V02_RS11205
uniprot id: A0A1B1SBN7
names: Similarity
messages: Belongs to the peptidase S66 family.

1796646:A4V02 RS06710
gene id: 1796646:A4V02_RS06710
uniprot id: A0A1B1S9F7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1796646:A4V02 RS02420
gene id: 1796646:A4V02_RS02420
uniprot id: A0A1B1SD01
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1796646:A4V02 RS13690
gene id: 1796646:A4V02_RS13690
uniprot id: A0A1B1SD00
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1796646:A4V02 RS12955
gene id: 1796646:A4V02_RS12955
uniprot id: A0A1B1SCT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1796646:A4V02 RS12945
gene id: 1796646:A4V02_RS12945
uniprot id: A0A1B1SCI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1796646:A4V02 RS08340
gene id: 1796646:A4V02_RS08340
uniprot id: A0A1B1SA77
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1796646:A4V02 RS10705
gene id: 1796646:A4V02_RS10705
uniprot id: A0A1B1SBE7
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1796646:A4V02 RS12175
gene id: 1796646:A4V02_RS12175
uniprot id: A0A1B1SC68
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1796646:A4V02 RS12140
gene id: 1796646:A4V02_RS12140
uniprot id: A0A1B1SC14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1796646:A4V02 RS06665
gene id: 1796646:A4V02_RS06665
uniprot id: A0A1B1S9F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1796646:A4V02 RS07585
gene id: 1796646:A4V02_RS07585
uniprot id: A0A1B1SD79
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1796646:A4V02 RS09240
gene id: 1796646:A4V02_RS09240
uniprot id: A0A1B1SAQ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796646:A4V02 RS02705
gene id: 1796646:A4V02_RS02705
uniprot id: A0A1B1S7F7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1796646:A4V02 RS11715
gene id: 1796646:A4V02_RS11715
uniprot id: A0A1B1SBY0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS07010
gene id: 1796646:A4V02_RS07010
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS07125
gene id: 1796646:A4V02_RS07125
uniprot id: A0A1B1SDI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1796646:A4V02 RS07255
gene id: 1796646:A4V02_RS07255
uniprot id: A0A1B1S9Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1796646:A4V02 RS03830
gene id: 1796646:A4V02_RS03830
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS08305
gene id: 1796646:A4V02_RS08305
uniprot id: A0A1B1SA86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1796646:A4V02 RS08265
gene id: 1796646:A4V02_RS08265
uniprot id: A0A1B1SAB0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796646:A4V02 RS07665
gene id: 1796646:A4V02_RS07665
uniprot id: A0A1B1SDI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS02845
gene id: 1796646:A4V02_RS02845
uniprot id: A0A1B1S7I3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1796646:A4V02 RS08255
gene id: 1796646:A4V02_RS08255
uniprot id: A0A1B1SA82
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1796646:A4V02 RS12830
gene id: 1796646:A4V02_RS12830
uniprot id: A0A1B1SCK6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS01700
gene id: 1796646:A4V02_RS01700
uniprot id: A0A1B1S705
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1796646:A4V02 RS09705
gene id: 1796646:A4V02_RS09705
uniprot id: A0A1B1SAX2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1796646:A4V02 RS11995
gene id: 1796646:A4V02_RS11995
uniprot id: A0A1B1SC34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1796646:A4V02 RS02805
gene id: 1796646:A4V02_RS02805
uniprot id: A0A1B1S7H9
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS10925
gene id: 1796646:A4V02_RS10925
uniprot id: A0A1B1SBJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1796646:A4V02 RS07110
gene id: 1796646:A4V02_RS07110
uniprot id: A0A1B1S9N5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1796646:A4V02 RS04295
gene id: 1796646:A4V02_RS04295
uniprot id: A0A1B1S879
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS08565
gene id: 1796646:A4V02_RS08565
uniprot id: A0A1B1SAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1796646:A4V02 RS12895
gene id: 1796646:A4V02_RS12895
uniprot id: A0A1B1SCH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1796646:A4V02 RS00320
gene id: 1796646:A4V02_RS00320
uniprot id: A0A1B1S6B8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796646:A4V02 RS00255
gene id: 1796646:A4V02_RS00255
uniprot id: A0A1B1S6A7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1796646:A4V02 RS01325
gene id: 1796646:A4V02_RS01325
uniprot id: A0A1B1S6T6
names: Similarity
messages: Belongs to the UPF0047 family.

1796646:A4V02 RS06465
gene id: 1796646:A4V02_RS06465
uniprot id: A0A1B1S9A3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1796646:A4V02 RS01405
gene id: 1796646:A4V02_RS01405
uniprot id: A0A1B1S6V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1796646:A4V02 RS00590
gene id: 1796646:A4V02_RS00590
uniprot id: A0A1B1S6G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1796646:A4V02 RS04875
gene id: 1796646:A4V02_RS04875
uniprot id: A0A1B1S8H3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1796646:A4V02 RS02800
gene id: 1796646:A4V02_RS02800
uniprot id: A0A1B1SDD9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1796646:A4V02 RS03995
gene id: 1796646:A4V02_RS03995
uniprot id: A0A1B1S825
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

1796646:A4V02 RS07950
gene id: 1796646:A4V02_RS07950
uniprot id: A0A1B1SA19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796646:A4V02 RS09625
gene id: 1796646:A4V02_RS09625
uniprot id: A0A1B1SAW3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1796646:A4V02 RS02370
gene id: 1796646:A4V02_RS02370
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS01865
gene id: 1796646:A4V02_RS01865
uniprot id: A0A1B1S723
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1796646:A4V02 RS12355
gene id: 1796646:A4V02_RS12355
uniprot id: A0A1B1SC91
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1796646:A4V02 RS08165
gene id: 1796646:A4V02_RS08165
uniprot id: A0A1B1SA51
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1796646:A4V02 RS09635
gene id: 1796646:A4V02_RS09635
uniprot id: A0A1B1SAV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1796646:A4V02 RS00020
gene id: 1796646:A4V02_RS00020
uniprot id: A0A1B1S665
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1796646:A4V02 RS09865
gene id: 1796646:A4V02_RS09865
uniprot id: A0A1B1SAZ9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1796646:A4V02 RS09255
gene id: 1796646:A4V02_RS09255
uniprot id: A0A1B1SAQ4
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS07805
gene id: 1796646:A4V02_RS07805
uniprot id: A0A1B1S9Z5
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS10080
gene id: 1796646:A4V02_RS10080
uniprot id: A0A1B1SB33
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796646:A4V02 RS11740
gene id: 1796646:A4V02_RS11740
uniprot id: A0A1B1SBU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1796646:A4V02 RS12935
gene id: 1796646:A4V02_RS12935
uniprot id: A0A1B1SCK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1796646:A4V02 RS10605
gene id: 1796646:A4V02_RS10605
uniprot id: A0A1B1SBB6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1796646:A4V02 RS07630
gene id: 1796646:A4V02_RS07630
uniprot id: A0A1B1S9W6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1796646:A4V02 RS13025
gene id: 1796646:A4V02_RS13025
uniprot id: A0A1B1SCH6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1796646:A4V02 RS06660
gene id: 1796646:A4V02_RS06660
uniprot id: A0A1B1S9C9
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS08745
gene id: 1796646:A4V02_RS08745
uniprot id: A0A1B1SAH0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796646:A4V02 RS05195
gene id: 1796646:A4V02_RS05195
uniprot id: A0A1B1S8N0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1796646:A4V02 RS11330
gene id: 1796646:A4V02_RS11330
uniprot id: A0A1B1SBY4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796646:A4V02 RS00410
gene id: 1796646:A4V02_RS00410
uniprot id: A0A1B1S6D7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1796646:A4V02 RS04095
gene id: 1796646:A4V02_RS04095
uniprot id: A0A1B1S844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1796646:A4V02 RS09775
gene id: 1796646:A4V02_RS09775
uniprot id: A0A1B1SAY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1796646:A4V02 RS09505
gene id: 1796646:A4V02_RS09505
uniprot id: A0A1B1SAT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1796646:A4V02 RS00935
gene id: 1796646:A4V02_RS00935
uniprot id: A0A1B1S6M9
names: Similarity
messages: Belongs to the DprA/Smf family.

1796646:A4V02 RS13015
gene id: 1796646:A4V02_RS13015
uniprot id: A0A1B1SCI3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1796646:A4V02 RS00130
gene id: 1796646:A4V02_RS00130
uniprot id: A0A1B1S691
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1796646:A4V02 RS11855
gene id: 1796646:A4V02_RS11855
uniprot id: A0A1B1SC86
names: Similarity
messages: Belongs to the peptidase S8 family.

1796646:A4V02 RS02285
gene id: 1796646:A4V02_RS02285
uniprot id: A0A1B1S784
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1796646:A4V02 RS00495
gene id: 1796646:A4V02_RS00495
uniprot id: A0A1B1S6F6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS09715
gene id: 1796646:A4V02_RS09715
uniprot id: A0A1B1SAZ1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1796646:A4V02 RS07130
gene id: 1796646:A4V02_RS07130
uniprot id: A0A1B1S9M3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS11565
gene id: 1796646:A4V02_RS11565
uniprot id: A0A1B1SBV0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1796646:A4V02 RS07940
gene id: 1796646:A4V02_RS07940
uniprot id: A0A1B1SA11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796646:A4V02 RS13010
gene id: 1796646:A4V02_RS13010
uniprot id: A0A1B1SCH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1796646:A4V02 RS12650
gene id: 1796646:A4V02_RS12650
uniprot id: A0A1B1SCA3
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS12840
gene id: 1796646:A4V02_RS12840
uniprot id: A0A1B1SCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1796646:A4V02 RS02075
gene id: 1796646:A4V02_RS02075
uniprot id: A0A1B1S752
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1796646:A4V02 RS04330
gene id: 1796646:A4V02_RS04330
uniprot id: A0A1B1S884
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1796646:A4V02 RS13275
gene id: 1796646:A4V02_RS13275
uniprot id: A0A1B1SCN7
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS12125
gene id: 1796646:A4V02_RS12125
uniprot id: A0A1B1SDH3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1796646:A4V02 RS00630
gene id: 1796646:A4V02_RS00630
uniprot id: A0A1B1S6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1796646:A4V02 RS02600
gene id: 1796646:A4V02_RS02600
uniprot id: A0A1B1S7E1
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS00905
gene id: 1796646:A4V02_RS00905
uniprot id: A0A1B1S6L8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1796646:A4V02 RS03305
gene id: 1796646:A4V02_RS03305
uniprot id: A0A1B1SD26
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS07605
gene id: 1796646:A4V02_RS07605
uniprot id: A0A1B1S9W1
names: Similarity
messages: Belongs to the YicC/YloC family.

1796646:A4V02 RS08495
gene id: 1796646:A4V02_RS08495
uniprot id: A0A1B1SAA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1796646:A4V02 RS05200
gene id: 1796646:A4V02_RS05200
uniprot id: A0A1B1S8N6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS12850
gene id: 1796646:A4V02_RS12850
uniprot id: A0A1B1SCG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1796646:A4V02 RS02730
gene id: 1796646:A4V02_RS02730
uniprot id: A0A1B1SD16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1796646:A4V02 RS02710
gene id: 1796646:A4V02_RS02710
uniprot id: A0A1B1S7F9
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1796646:A4V02 RS11225
gene id: 1796646:A4V02_RS11225
uniprot id: A0A1B1SBW4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1796646:A4V02 RS01425
gene id: 1796646:A4V02_RS01425
uniprot id: A0A1B1S6V1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1796646:A4V02 RS07870
gene id: 1796646:A4V02_RS07870
uniprot id: A0A1B1SA24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1796646:A4V02 RS04745
gene id: 1796646:A4V02_RS04745
uniprot id: A0A1B1S8G3
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS00645
gene id: 1796646:A4V02_RS00645
uniprot id: A0A1B1S6H8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1796646:A4V02 RS04280
gene id: 1796646:A4V02_RS04280
uniprot id: A0A1B1S870
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1796646:A4V02 RS11310
gene id: 1796646:A4V02_RS11310
uniprot id: A0A1B1SBQ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS02905
gene id: 1796646:A4V02_RS02905
uniprot id: A0A1B1S7J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1796646:A4V02 RS11035
gene id: 1796646:A4V02_RS11035
uniprot id: A0A1B1SBK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1796646:A4V02 RS10765
gene id: 1796646:A4V02_RS10765
uniprot id: A0A1B1SBF3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1796646:A4V02 RS09250
gene id: 1796646:A4V02_RS09250
uniprot id: A0A1B1SAP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS06685
gene id: 1796646:A4V02_RS06685
uniprot id: A0A1B1SD68
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1796646:A4V02 RS07935
gene id: 1796646:A4V02_RS07935
uniprot id: A0A1B1SA12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796646:A4V02 RS11050
gene id: 1796646:A4V02_RS11050
uniprot id: A0A1B1SBF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1796646:A4V02 RS01720
gene id: 1796646:A4V02_RS01720
uniprot id: A0A1B1S6Z7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS12875
gene id: 1796646:A4V02_RS12875
uniprot id: A0A1B1SCE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1796646:A4V02 RS10980
gene id: 1796646:A4V02_RS10980
uniprot id: A0A1B1SBL3
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS05045
gene id: 1796646:A4V02_RS05045
uniprot id: A0A1B1S8L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1796646:A4V02 RS12595
gene id: 1796646:A4V02_RS12595
uniprot id: A0A1B1SC93
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1796646:A4V02 RS04400
gene id: 1796646:A4V02_RS04400
uniprot id: A0A1B1S885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1796646:A4V02 RS00510
gene id: 1796646:A4V02_RS00510
uniprot id: A0A1B1SCZ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS04410
gene id: 1796646:A4V02_RS04410
uniprot id: A0A1B1S893
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1796646:A4V02 RS12675
gene id: 1796646:A4V02_RS12675
uniprot id: A0A1B1SCF2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1796646:A4V02 RS02405
gene id: 1796646:A4V02_RS02405
uniprot id: A0A1B1S7A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1796646:A4V02 RS00900
gene id: 1796646:A4V02_RS00900
uniprot id: A0A1B1S6L7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1796646:A4V02 RS06615
gene id: 1796646:A4V02_RS06615
uniprot id: A0A1B1S9E9
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1796646:A4V02 RS00815
gene id: 1796646:A4V02_RS00815
uniprot id: A0A1B1S6K9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1796646:A4V02 RS13115
gene id: 1796646:A4V02_RS13115
uniprot id: A0A1B1SCN0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS13740
gene id: 1796646:A4V02_RS13740
uniprot id: A0A1B1SD10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS13075
gene id: 1796646:A4V02_RS13075
uniprot id: A0A1B1SCV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1796646:A4V02 RS12940
gene id: 1796646:A4V02_RS12940
uniprot id: A0A1B1SCK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1796646:A4V02 RS05955
gene id: 1796646:A4V02_RS05955
uniprot id: A0A1B1S922
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1796646:A4V02 RS07750
gene id: 1796646:A4V02_RS07750
uniprot id: A0A1B1S9Y7
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS02930
gene id: 1796646:A4V02_RS02930
uniprot id: A0A1B1S7K2
names: Similarity
messages: Belongs to the peptidase S41A family.

1796646:A4V02 RS12890
gene id: 1796646:A4V02_RS12890
uniprot id: A0A1B1SCJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1796646:A4V02 RS10485
gene id: 1796646:A4V02_RS10485
uniprot id: A0A1B1SBA0
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS07155
gene id: 1796646:A4V02_RS07155
uniprot id: A0A1B1S9M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS10675
gene id: 1796646:A4V02_RS10675
uniprot id: A0A1B1SBG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1796646:A4V02 RS12160
gene id: 1796646:A4V02_RS12160
uniprot id: A0A1B1SC09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS11435
gene id: 1796646:A4V02_RS11435
uniprot id: A0A1B1SBN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS02715
gene id: 1796646:A4V02_RS02715
uniprot id: A0A1B1S7G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS11795
gene id: 1796646:A4V02_RS11795
uniprot id: A0A1B1SC76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1796646:A4V02 RS10680
gene id: 1796646:A4V02_RS10680
uniprot id: A0A1B1SDF3
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1796646:A4V02 RS02520
gene id: 1796646:A4V02_RS02520
uniprot id: A0A1B1S7D4
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1796646:A4V02 RS11020
gene id: 1796646:A4V02_RS11020
uniprot id: A0A1B1SBG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1796646:A4V02 RS10970
gene id: 1796646:A4V02_RS10970
uniprot id: A0A1B1SBK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1796646:A4V02 RS07120
gene id: 1796646:A4V02_RS07120
uniprot id: A0A1B1S9L4
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1796646:A4V02 RS09055
gene id: 1796646:A4V02_RS09055
uniprot id: A0A1V0QE80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1796646:A4V02 RS00690
gene id: 1796646:A4V02_RS00690
uniprot id: A0A1B1S6J1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1796646:A4V02 RS02150
gene id: 1796646:A4V02_RS02150
uniprot id: A0A1B1S768
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1796646:A4V02 RS06795
gene id: 1796646:A4V02_RS06795
uniprot id: A0A1B1S9F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1796646:A4V02 RS00575
gene id: 1796646:A4V02_RS00575
uniprot id: A0A1B1S6G7
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS02225
gene id: 1796646:A4V02_RS02225
uniprot id: A0A1B1S782
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1796646:A4V02 RS09060
gene id: 1796646:A4V02_RS09060
uniprot id: A0A1B1SDG2
names: Similarity
messages: Belongs to the HSP15 family.

1796646:A4V02 RS09195
gene id: 1796646:A4V02_RS09195
uniprot id: A0A1B1SAP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1796646:A4V02 RS09555
gene id: 1796646:A4V02_RS09555
uniprot id: A0A1B1SAV2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796646:A4V02 RS06875
gene id: 1796646:A4V02_RS06875
uniprot id: A0A1B1S9K7
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1796646:A4V02 RS01330
gene id: 1796646:A4V02_RS01330
uniprot id: A0A1B1S6U0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1796646:A4V02 RS09685
gene id: 1796646:A4V02_RS09685
uniprot id: A0A1B1SAX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS00325
gene id: 1796646:A4V02_RS00325
uniprot id: A0A1B1S6B3
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1796646:A4V02 RS01290
gene id: 1796646:A4V02_RS01290
uniprot id: A0A1B1S6T0
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS02395
gene id: 1796646:A4V02_RS02395
uniprot id: A0A1B1S7A8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1796646:A4V02 RS02825
gene id: 1796646:A4V02_RS02825
uniprot id: A0A1B1SD09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1796646:A4V02 RS07420
gene id: 1796646:A4V02_RS07420
uniprot id: A0A1B1S9S5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1796646:A4V02 RS02080
gene id: 1796646:A4V02_RS02080
uniprot id: A0A1B1S749
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1796646:A4V02 RS04265
gene id: 1796646:A4V02_RS04265
uniprot id: A0A1B1S865
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates ribosomal protein L11.

1796646:A4V02 RS03760
gene id: 1796646:A4V02_RS03760
uniprot id: A0A1B1S7Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1796646:A4V02 RS11280
gene id: 1796646:A4V02_RS11280
uniprot id: A0A1B1SBK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1796646:A4V02 RS00880
gene id: 1796646:A4V02_RS00880
uniprot id: A0A1V0QDZ5
names: Similarity
messages: Belongs to the peptidase S41A family.

1796646:A4V02 RS11810
gene id: 1796646:A4V02_RS11810
uniprot id: A0A1B1SDS1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1796646:A4V02 RS06650
gene id: 1796646:A4V02_RS06650
uniprot id: A0A1B1S9C8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1796646:A4V02 RS00350
gene id: 1796646:A4V02_RS00350
uniprot id: A0A1B1S6B9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

1796646:A4V02 RS07450
gene id: 1796646:A4V02_RS07450
uniprot id: A0A1B1S9T8
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS10625
gene id: 1796646:A4V02_RS10625
uniprot id: A0A1B1SBD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1796646:A4V02 RS09840
gene id: 1796646:A4V02_RS09840
uniprot id: A0A1B1SAZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1796646:A4V02 RS06900
gene id: 1796646:A4V02_RS06900
uniprot id: A0A1B1S9I0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1796646:A4V02 RS12600
gene id: 1796646:A4V02_RS12600
uniprot id: A0A1B1SC94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1796646:A4V02 RS09365
gene id: 1796646:A4V02_RS09365
uniprot id: A0A1B1SAS5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1796646:A4V02 RS02140
gene id: 1796646:A4V02_RS02140
uniprot id: A0A1B1S776
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS07930
gene id: 1796646:A4V02_RS07930
uniprot id: A0A1B1SA20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796646:A4V02 RS02900
gene id: 1796646:A4V02_RS02900
uniprot id: A0A1B1S7J3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1796646:A4V02 RS00305
gene id: 1796646:A4V02_RS00305
uniprot id: A0A1B1S6C5
names: Subcellular Location Annotation
messages: cytosol

1796646:A4V02 RS08040
gene id: 1796646:A4V02_RS08040
uniprot id: A0A1B1SA31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1796646:A4V02 RS08740
gene id: 1796646:A4V02_RS08740
uniprot id: A0A1B1SAG3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1796646:A4V02 RS08930
gene id: 1796646:A4V02_RS08930
uniprot id: A0A1B1SAJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1796646:A4V02 RS13555
gene id: 1796646:A4V02_RS13555
uniprot id: A0A1B1SCT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1796646:A4V02 RS05030
gene id: 1796646:A4V02_RS05030
uniprot id: A0A1B1S8K8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1796646:A4V02 RS01795
gene id: 1796646:A4V02_RS01795
uniprot id: A0A1B1S710
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1796646:A4V02 RS11010
gene id: 1796646:A4V02_RS11010
uniprot id: A0A1B1SBH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1796646:A4V02 RS08920
gene id: 1796646:A4V02_RS08920
uniprot id: A0A1B1SAJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1796646:A4V02 RS01705
gene id: 1796646:A4V02_RS01705
uniprot id: A0A1B1S701
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1796646:A4V02 RS09370
gene id: 1796646:A4V02_RS09370
uniprot id: A0A1B1SAS3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1796646:A4V02 RS06395
gene id: 1796646:A4V02_RS06395
uniprot id: A0A1B1S995
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1796646:A4V02 RS13460
gene id: 1796646:A4V02_RS13460
uniprot id: A0A1B1SCP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1796646:A4V02 RS02355
gene id: 1796646:A4V02_RS02355
uniprot id: A0A1B1S795
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1796646:A4V02 RS02835
gene id: 1796646:A4V02_RS02835
uniprot id: A0A1B1S7H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1796646:A4V02 RS05270
gene id: 1796646:A4V02_RS05270
uniprot id: A0A1B1S8Q3
names: Similarity
messages: Belongs to the aspartokinase family.

1796646:A4V02 RS01470
gene id: 1796646:A4V02_RS01470
uniprot id: A0A1B1SCZ5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1796646:A4V02 RS01155
gene id: 1796646:A4V02_RS01155
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS06825
gene id: 1796646:A4V02_RS06825
uniprot id: A0A1B1S9J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1796646:A4V02 RS05125
gene id: 1796646:A4V02_RS05125
uniprot id: A0A1B1S8L3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS02670
gene id: 1796646:A4V02_RS02670
uniprot id: A0A1B1SD23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1796646:A4V02 RS05150
gene id: 1796646:A4V02_RS05150
uniprot id: A0A1B1S8M5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS08800
gene id: 1796646:A4V02_RS08800
uniprot id: A0A1B1SAG6
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS13570
gene id: 1796646:A4V02_RS13570
uniprot id: A0A1B1SCW0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1796646:A4V02 RS00715
gene id: 1796646:A4V02_RS00715
uniprot id: A0A1B1S6I7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796646:A4V02 RS05450
gene id: 1796646:A4V02_RS05450
uniprot id: A0A1B1S8T9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1796646:A4V02 RS12755
gene id: 1796646:A4V02_RS12755
uniprot id: A0A1B1SCD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1796646:A4V02 RS06815
gene id: 1796646:A4V02_RS06815
uniprot id: A0A1B1S9I5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1796646:A4V02 RS10985
gene id: 1796646:A4V02_RS10985
uniprot id: A0A1B1SBL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1796646:A4V02 RS11005
gene id: 1796646:A4V02_RS11005
uniprot id: A0A1B1SBG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1796646:A4V02 RS08910
gene id: 1796646:A4V02_RS08910
uniprot id: A0A1B1SAI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1796646:A4V02 RS12950
gene id: 1796646:A4V02_RS12950
uniprot id: A0A1B1SCI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1796646:A4V02 RS04215
gene id: 1796646:A4V02_RS04215
uniprot id: A0A1B1S862
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1796646:A4V02 RS08810
gene id: 1796646:A4V02_RS08810
uniprot id: A0A1B1SAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1796646:A4V02 RS11690
gene id: 1796646:A4V02_RS11690
uniprot id: A0A1B1SBT3
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS07410
gene id: 1796646:A4V02_RS07410
uniprot id: A0A1B1S9S7
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS11105
gene id: 1796646:A4V02_RS11105
uniprot id: A0A1B1SBU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1796646:A4V02 RS07600
gene id: 1796646:A4V02_RS07600
uniprot id: A0A1B1S9W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1796646:A4V02 RS02610
gene id: 1796646:A4V02_RS02610
uniprot id: A0A1B1SD12
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1796646:A4V02 RS12560
gene id: 1796646:A4V02_RS12560
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS11080
gene id: 1796646:A4V02_RS11080
uniprot id: A0A1B1SBL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS12135
gene id: 1796646:A4V02_RS12135
uniprot id: A0A1B1SCF0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS04355
gene id: 1796646:A4V02_RS04355
uniprot id: A0A1B1S887
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1796646:A4V02 RS04870
gene id: 1796646:A4V02_RS04870
uniprot id: A0A1B1S8F5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1796646:A4V02 RS12055
gene id: 1796646:A4V02_RS12055
uniprot id: A0A1B1SC46
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1796646:A4V02 RS08940
gene id: 1796646:A4V02_RS08940
uniprot id: A0A1B1SAJ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS09700
gene id: 1796646:A4V02_RS09700
uniprot id: A0A1B1SAW2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1796646:A4V02 RS08215
gene id: 1796646:A4V02_RS08215
uniprot id: A0A1B1SA55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1796646:A4V02 RS08720
gene id: 1796646:A4V02_RS08720
uniprot id: A0A1B1SAF4
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1796646:A4V02 RS05185
gene id: 1796646:A4V02_RS05185
uniprot id: A0A1B1S8P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1796646:A4V02 RS09960
gene id: 1796646:A4V02_RS09960
uniprot id: A0A1B1SAZ7
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS07100
gene id: 1796646:A4V02_RS07100
uniprot id: A0A1B1S9M5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1796646:A4V02 RS12470
gene id: 1796646:A4V02_RS12470
uniprot id: A0A1B1SCJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1796646:A4V02 RS13565
gene id: 1796646:A4V02_RS13565
uniprot id: A0A1B1SCY1
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1796646:A4V02 RS06820
gene id: 1796646:A4V02_RS06820
uniprot id: A0A1B1S9H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1796646:A4V02 RS05090
gene id: 1796646:A4V02_RS05090
uniprot id: A0A1B1S8L9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1796646:A4V02 RS11940
gene id: 1796646:A4V02_RS11940
uniprot id: A0A1B1SC28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1796646:A4V02 RS10440
gene id: 1796646:A4V02_RS10440
uniprot id: A0A1B1SB80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1796646:A4V02 RS12965
gene id: 1796646:A4V02_RS12965
uniprot id: A0A1B1SCH4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1796646:A4V02 RS09485
gene id: 1796646:A4V02_RS09485
uniprot id: A0A1B1SAU5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS00660
gene id: 1796646:A4V02_RS00660
uniprot id: A0A1B1S6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1796646:A4V02 RS07915
gene id: 1796646:A4V02_RS07915
uniprot id: A0A1B1SA13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1796646:A4V02 RS12855
gene id: 1796646:A4V02_RS12855
uniprot id: A0A1B1SCR3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1796646:A4V02 RS05950
gene id: 1796646:A4V02_RS05950
uniprot id: A0A1B1S933
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1796646:A4V02 RS12990
gene id: 1796646:A4V02_RS12990
uniprot id: A0A1B1SCL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1796646:A4V02 RS00490
gene id: 1796646:A4V02_RS00490
uniprot id: A0A1B1S6F3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1796646:A4V02 RS08270
gene id: 1796646:A4V02_RS08270
uniprot id: A0A1B1SA60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1796646:A4V02 RS00530
gene id: 1796646:A4V02_RS00530
uniprot id: A0A1B1S6G1
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1796646:A4V02 RS06695
gene id: 1796646:A4V02_RS06695
uniprot id: A0A1B1S9F3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1796646:A4V02 RS09305
gene id: 1796646:A4V02_RS09305
uniprot id: A0A1B1SAQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1796646:A4V02 RS04825
gene id: 1796646:A4V02_RS04825
uniprot id: A0A1B1S8I5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1796646:A4V02 RS08950
gene id: 1796646:A4V02_RS08950
uniprot id: A0A1B1SAK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1796646:A4V02 RS09955
gene id: 1796646:A4V02_RS09955
uniprot id: A0A1B1SB10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS08885
gene id: 1796646:A4V02_RS08885
uniprot id: A0A1B1SAI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1796646:A4V02 RS02220
gene id: 1796646:A4V02_RS02220
uniprot id: A0A1B1S773
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1796646:A4V02 RS07470
gene id: 1796646:A4V02_RS07470
uniprot id: A0A1B1S9T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS03330
gene id: 1796646:A4V02_RS03330
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS11190
gene id: 1796646:A4V02_RS11190
uniprot id: A0A1B1SBI9
names: Similarity
messages: Belongs to the GARS family.

1796646:A4V02 RS01285
gene id: 1796646:A4V02_RS01285
uniprot id: A0A1B1S6T2
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS11055
gene id: 1796646:A4V02_RS11055
uniprot id: A0A1B1SBT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1796646:A4V02 RS07070
gene id: 1796646:A4V02_RS07070
uniprot id: A0A1B1S9K4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1796646:A4V02 RS09205
gene id: 1796646:A4V02_RS09205
uniprot id: A0A1B1SAP5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1796646:A4V02 RS08185
gene id: 1796646:A4V02_RS08185
uniprot id: A0A1B1SA72
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1796646:A4V02 RS07905
gene id: 1796646:A4V02_RS07905
uniprot id: A0A1B1SA16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1796646:A4V02 RS00640
gene id: 1796646:A4V02_RS00640
uniprot id: A0A1B1S6H7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1796646:A4V02 RS00025
gene id: 1796646:A4V02_RS00025
uniprot id: A0A1B1S673
names: Similarity
messages: Belongs to the DapA family.

1796646:A4V02 RS03405
gene id: 1796646:A4V02_RS03405
uniprot id: A0A1B1S7T1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1796646:A4V02 RS09270
gene id: 1796646:A4V02_RS09270
uniprot id: A0A1B1SAP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1796646:A4V02 RS12930
gene id: 1796646:A4V02_RS12930
uniprot id: A0A1B1SCM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1796646:A4V02 RS04845
gene id: 1796646:A4V02_RS04845
uniprot id: A0A1B1S8G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1796646:A4V02 RS07430
gene id: 1796646:A4V02_RS07430
uniprot id: A0A1B1S9Q8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1796646:A4V02 RS04360
gene id: 1796646:A4V02_RS04360
uniprot id: A0A1B1SD76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1796646:A4V02 RS02315
gene id: 1796646:A4V02_RS02315
uniprot id: A0A1B1S790
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1796646:A4V02 RS10805
gene id: 1796646:A4V02_RS10805
uniprot id: A0A1B1SBE4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1796646:A4V02 RS07175
gene id: 1796646:A4V02_RS07175
uniprot id: A0A1B1S9P1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1796646:A4V02 RS02415
gene id: 1796646:A4V02_RS02415
uniprot id: A0A1B1S7A9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS09935
gene id: 1796646:A4V02_RS09935
uniprot id: A0A1B1SB13
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1796646:A4V02 RS01800
gene id: 1796646:A4V02_RS01800
uniprot id: A0A1B1S711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1796646:A4V02 RS12905
gene id: 1796646:A4V02_RS12905
uniprot id: A0A1B1SCS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1796646:A4V02 RS04720
gene id: 1796646:A4V02_RS04720
uniprot id: A0A1V0QE29
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1796646:A4V02 RS04285
gene id: 1796646:A4V02_RS04285
uniprot id: A0A1B1S869
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1796646:A4V02 RS05525
gene id: 1796646:A4V02_RS05525
uniprot id: A0A1B1S8W2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1796646:A4V02 RS10855
gene id: 1796646:A4V02_RS10855
uniprot id: A0A1B1SBF0
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1796646:A4V02 RS02235
gene id: 1796646:A4V02_RS02235
uniprot id: A0A1V0QE09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS08955
gene id: 1796646:A4V02_RS08955
uniprot id: A0A1B1SAI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1796646:A4V02 RS05775
gene id: 1796646:A4V02_RS05775
uniprot id: A0A1B1SD26
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS07785
gene id: 1796646:A4V02_RS07785
uniprot id: A0A1B1S9Y4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796646:A4V02 RS05075
gene id: 1796646:A4V02_RS05075
uniprot id: A0A1B1S8K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1796646:A4V02 RS04855
gene id: 1796646:A4V02_RS04855
uniprot id: A0A1B1S8H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1796646:A4V02 RS08780
gene id: 1796646:A4V02_RS08780
uniprot id: A0A1B1SAG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS10035
gene id: 1796646:A4V02_RS10035
uniprot id: A0A1B1SDG1
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1796646:A4V02 RS05190
gene id: 1796646:A4V02_RS05190
uniprot id: A0A1B1S8N5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1796646:A4V02 RS05980
gene id: 1796646:A4V02_RS05980
uniprot id: A0A1B1S924
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1796646:A4V02 RS12325
gene id: 1796646:A4V02_RS12325
uniprot id: A0A1B1SC41
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS10470
gene id: 1796646:A4V02_RS10470
uniprot id: A0A1B1SB98
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS00940
gene id: 1796646:A4V02_RS00940
uniprot id: A0A1B1S6N5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1796646:A4V02 RS08715
gene id: 1796646:A4V02_RS08715
uniprot id: A0A1B1SAF7
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS01420
gene id: 1796646:A4V02_RS01420
uniprot id: A0A1B1S6U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS10345
gene id: 1796646:A4V02_RS10345
uniprot id: A0A1B1SB78
names: Similarity
messages: Belongs to the thioredoxin family.

1796646:A4V02 RS00265
gene id: 1796646:A4V02_RS00265
uniprot id: A0A1B1S6A5
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS10660
gene id: 1796646:A4V02_RS10660
uniprot id: A0A1B1SBC0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1796646:A4V02 RS10610
gene id: 1796646:A4V02_RS10610
uniprot id: A0A1B1SBB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1796646:A4V02 RS00115
gene id: 1796646:A4V02_RS00115
uniprot id: A0A1B1S678
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1796646:A4V02 RS07360
gene id: 1796646:A4V02_RS07360
uniprot id: A0A1B1S9R4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1796646:A4V02 RS13375
gene id: 1796646:A4V02_RS13375
uniprot id: A0A1B1SCP9
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS01845
gene id: 1796646:A4V02_RS01845
uniprot id: A0A1B1S724
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796646:A4V02 RS00665
gene id: 1796646:A4V02_RS00665
uniprot id: A0A1B1S6I3
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

1796646:A4V02 RS08035
gene id: 1796646:A4V02_RS08035
uniprot id: A0A1B1SA41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1796646:A4V02 RS09845
gene id: 1796646:A4V02_RS09845
uniprot id: A0A1B1SB00
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1796646:A4V02 RS13005
gene id: 1796646:A4V02_RS13005
uniprot id: A0A1B1SCV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1796646:A4V02 RS11165
gene id: 1796646:A4V02_RS11165
uniprot id: A0A1B1SBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS09615
gene id: 1796646:A4V02_RS09615
uniprot id: A0A1V0QEK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1796646:A4V02 RS12920
gene id: 1796646:A4V02_RS12920
uniprot id: A0A1B1SCH3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1796646:A4V02 RS07085
gene id: 1796646:A4V02_RS07085
uniprot id: A0A1B1S9L0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1796646:A4V02 RS08460
gene id: 1796646:A4V02_RS08460
uniprot id: A0A1B1SAB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1796646:A4V02 RS07250
gene id: 1796646:A4V02_RS07250
uniprot id: A0A1B1S9N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1796646:A4V02 RS06865
gene id: 1796646:A4V02_RS06865
uniprot id: A0A1B1S9J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

1796646:A4V02 RS12715
gene id: 1796646:A4V02_RS12715
uniprot id: A0A1B1SCB2
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS05470
gene id: 1796646:A4V02_RS05470
uniprot id: A0A1B1S8V0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS08030
gene id: 1796646:A4V02_RS08030
uniprot id: A0A1B1SA64
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS00735
gene id: 1796646:A4V02_RS00735
uniprot id: A0A1B1S6J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1796646:A4V02 RS04665
gene id: 1796646:A4V02_RS04665
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS08580
gene id: 1796646:A4V02_RS08580
uniprot id: A0A1B1SAC7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1796646:A4V02 RS08870
gene id: 1796646:A4V02_RS08870
uniprot id: A0A1B1SAI5
names: Similarity
messages: Belongs to the peptidase S13 family.

1796646:A4V02 RS12985
gene id: 1796646:A4V02_RS12985
uniprot id: A0A1B1SCL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1796646:A4V02 RS07730
gene id: 1796646:A4V02_RS07730
uniprot id: A0A1B1SDA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1796646:A4V02 RS12900
gene id: 1796646:A4V02_RS12900
uniprot id: A0A1B1SCH5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1796646:A4V02 RS08365
gene id: 1796646:A4V02_RS08365
uniprot id: A0A1B1SAB7
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS13615
gene id: 1796646:A4V02_RS13615
uniprot id: A0A1B1SCU1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS12040
gene id: 1796646:A4V02_RS12040
uniprot id: A0A1B1SBY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1796646:A4V02 RS11370
gene id: 1796646:A4V02_RS11370
uniprot id: A0A1B1SBS2
names: Similarity
messages: Belongs to the peptidase C69 family.

1796646:A4V02 RS13635
gene id: 1796646:A4V02_RS13635
uniprot id: A0A1B1SCX7
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS02260
gene id: 1796646:A4V02_RS02260
uniprot id: A0A1B1SD17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1796646:A4V02 RS08380
gene id: 1796646:A4V02_RS08380
uniprot id: A0A1B1SA94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1796646:A4V02 RS00140
gene id: 1796646:A4V02_RS00140
uniprot id: A0A1B1S688
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS05135
gene id: 1796646:A4V02_RS05135
uniprot id: A0A1B1S8M3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1796646:A4V02 RS06890
gene id: 1796646:A4V02_RS06890
uniprot id: A0A1B1S9I2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1796646:A4V02 RS12095
gene id: 1796646:A4V02_RS12095
uniprot id: A0A1B1SBZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1796646:A4V02 RS08280
gene id: 1796646:A4V02_RS08280
uniprot id: A0A1B1SA78
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS10030
gene id: 1796646:A4V02_RS10030
uniprot id: A0A1B1SB16
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS01490
gene id: 1796646:A4V02_RS01490
uniprot id: A0A1B1S6V4
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS10090
gene id: 1796646:A4V02_RS10090
uniprot id: A0A1B1SB23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1796646:A4V02 RS05415
gene id: 1796646:A4V02_RS05415
uniprot id: A0A1B1S8S4
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS02125
gene id: 1796646:A4V02_RS02125
uniprot id: A0A1B1S765
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1796646:A4V02 RS08295
gene id: 1796646:A4V02_RS08295
uniprot id: A0A1B1SA93
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS11275
gene id: 1796646:A4V02_RS11275
uniprot id: A0A1B1SBX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1796646:A4V02 RS00245
gene id: 1796646:A4V02_RS00245
uniprot id: A0A1B1S6B0
names: Similarity
messages: Belongs to the transketolase family.

1796646:A4V02 RS04840
gene id: 1796646:A4V02_RS04840
uniprot id: A0A1B1S8H1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1796646:A4V02 RS07235
gene id: 1796646:A4V02_RS07235
uniprot id: A0A1B1S9P2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1796646:A4V02 RS04020
gene id: 1796646:A4V02_RS04020
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS12495
gene id: 1796646:A4V02_RS12495
uniprot id: A0A1B1SCC7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1796646:A4V02 RS03370
gene id: 1796646:A4V02_RS03370
uniprot id: A0A1B1S7S8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1796646:A4V02 RS12765
gene id: 1796646:A4V02_RS12765
uniprot id: A0A1B1SCE9
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

1796646:A4V02 RS10100
gene id: 1796646:A4V02_RS10100
uniprot id: A0A1B1SB38
names: Similarity
messages: Belongs to the pyruvate kinase family.

1796646:A4V02 RS12170
gene id: 1796646:A4V02_RS12170
uniprot id: A0A1B1SDF1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1796646:A4V02 RS13190
gene id: 1796646:A4V02_RS13190
uniprot id: A0A1B1SD28
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1796646:A4V02 RS10465
gene id: 1796646:A4V02_RS10465
uniprot id: A0A1B1SB84
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS13505
gene id: 1796646:A4V02_RS13505
uniprot id: A0A1B1SCS1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1796646:A4V02 RS09765
gene id: 1796646:A4V02_RS09765
uniprot id: A0A1B1SAX1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1796646:A4V02 RS07685
gene id: 1796646:A4V02_RS07685
uniprot id: A0A1B1S9Y0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1796646:A4V02 RS10725
gene id: 1796646:A4V02_RS10725
uniprot id: A0A1B1SBG1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1796646:A4V02 RS10120
gene id: 1796646:A4V02_RS10120
uniprot id: A0A1B1SB45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1796646:A4V02 RS02675
gene id: 1796646:A4V02_RS02675
uniprot id: A0A1B1S7G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1796646:A4V02 RS11605
gene id: 1796646:A4V02_RS11605
uniprot id: A0A1B1SBR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS07230
gene id: 1796646:A4V02_RS07230
uniprot id: A0A1B1S9Q3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1796646:A4V02 RS04115
gene id: 1796646:A4V02_RS04115
uniprot id: A0A1B1S845
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1796646:A4V02 RS07690
gene id: 1796646:A4V02_RS07690
uniprot id: A0A1B1S9Y5
names: Similarity
messages: Belongs to the glutamate synthase family.

1796646:A4V02 RS09010
gene id: 1796646:A4V02_RS09010
uniprot id: A0A1B1SAL3
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1796646:A4V02 RS07765
gene id: 1796646:A4V02_RS07765
uniprot id: A0A1B1SA08
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS08180
gene id: 1796646:A4V02_RS08180
uniprot id: A0A1B1SA68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1796646:A4V02 RS03115
gene id: 1796646:A4V02_RS03115
uniprot id: A0A1B1S7N2
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS05575
gene id: 1796646:A4V02_RS05575
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS11285
gene id: 1796646:A4V02_RS11285
uniprot id: A0A1B1SBL8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1796646:A4V02 RS08515
gene id: 1796646:A4V02_RS08515
uniprot id: A0A1B1SAD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1796646:A4V02 RS02865
gene id: 1796646:A4V02_RS02865
uniprot id: A0A1B1S7J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1796646:A4V02 RS06350
gene id: 1796646:A4V02_RS06350
uniprot id: A0A1B1S994
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1796646:A4V02 RS06715
gene id: 1796646:A4V02_RS06715
uniprot id: A0A1B1S9F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1796646:A4V02 RS11730
gene id: 1796646:A4V02_RS11730
uniprot id: A0A1B1SBX8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS12860
gene id: 1796646:A4V02_RS12860
uniprot id: A0A1B1SCD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1796646:A4V02 RS10025
gene id: 1796646:A4V02_RS10025
uniprot id: A0A1B1SB37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1796646:A4V02 RS13255
gene id: 1796646:A4V02_RS13255
uniprot id: A0A1B1SD38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1796646:A4V02 RS09395
gene id: 1796646:A4V02_RS09395
uniprot id: A0A1B1SAS2
names: Similarity
messages: Belongs to the peptidase S49 family.

1796646:A4V02 RS02245
gene id: 1796646:A4V02_RS02245
uniprot id: A0A1B1S787
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS01770
gene id: 1796646:A4V02_RS01770
uniprot id: A0A1B1S702
names: Similarity
messages: Belongs to the threonine synthase family.

1796646:A4V02 RS10735
gene id: 1796646:A4V02_RS10735
uniprot id: A0A1B1SBH2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1796646:A4V02 RS01430
gene id: 1796646:A4V02_RS01430
uniprot id: A0A1B1S6V5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1796646:A4V02 RS01740
gene id: 1796646:A4V02_RS01740
uniprot id: A0A1B1S704
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1796646:A4V02 RS07615
gene id: 1796646:A4V02_RS07615
uniprot id: A0A1B1S9W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1796646:A4V02 RS02070
gene id: 1796646:A4V02_RS02070
uniprot id: A0A1B1SD54
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796646:A4V02 RS00430
gene id: 1796646:A4V02_RS00430
uniprot id: A0A1B1S6D6
names: Similarity
messages: Belongs to the XseB family.

1796646:A4V02 RS00145
gene id: 1796646:A4V02_RS00145
uniprot id: A0A1B1S692
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1796646:A4V02 RS10515
gene id: 1796646:A4V02_RS10515
uniprot id: A0A1B1SBA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS07170
gene id: 1796646:A4V02_RS07170
uniprot id: A0A1B1S9P0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1796646:A4V02 RS11450
gene id: 1796646:A4V02_RS11450
uniprot id: A0A1B1SBN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1796646:A4V02 RS02790
gene id: 1796646:A4V02_RS02790
uniprot id: A0A1B1S7H7
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS08050
gene id: 1796646:A4V02_RS08050
uniprot id: A0A1B1SA44
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1796646:A4V02 RS12490
gene id: 1796646:A4V02_RS12490
uniprot id: A0A1B1SC74
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1796646:A4V02 RS10290
gene id: 1796646:A4V02_RS10290
uniprot id: A0A1B1SB72
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1796646:A4V02 RS01735
gene id: 1796646:A4V02_RS01735
uniprot id: A0A1B1S700
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1796646:A4V02 RS03395
gene id: 1796646:A4V02_RS03395
uniprot id: A0A1B1S7S7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1796646:A4V02 RS09420
gene id: 1796646:A4V02_RS09420
uniprot id: A0A1B1SAT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS10955
gene id: 1796646:A4V02_RS10955
uniprot id: A0A1B1SBG6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1796646:A4V02 RS04405
gene id: 1796646:A4V02_RS04405
uniprot id: A0A1B1S8A2
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1796646:A4V02 RS04755
gene id: 1796646:A4V02_RS04755
uniprot id: A0A1B1S8F7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796646:A4V02 RS08385
gene id: 1796646:A4V02_RS08385
uniprot id: A0A1B1SAB1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1796646:A4V02 RS10585
gene id: 1796646:A4V02_RS10585
uniprot id: A0A1B1SBB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1796646:A4V02 RS00440
gene id: 1796646:A4V02_RS00440
uniprot id: A0A1B1S6E0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1796646:A4V02 RS06585
gene id: 1796646:A4V02_RS06585
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS08450
gene id: 1796646:A4V02_RS08450
uniprot id: A0A1B1SA99
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1796646:A4V02 RS08355
gene id: 1796646:A4V02_RS08355
uniprot id: A0A1B1SA84
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS04200
gene id: 1796646:A4V02_RS04200
uniprot id: A0A1B1S851
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1796646:A4V02 RS01495
gene id: 1796646:A4V02_RS01495
uniprot id: A0A1B1S6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS10125
gene id: 1796646:A4V02_RS10125
uniprot id: A0A1B1SB40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1796646:A4V02 RS09185
gene id: 1796646:A4V02_RS09185
uniprot id: A0A1B1SAM7
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1796646:A4V02 RS11045
gene id: 1796646:A4V02_RS11045
uniprot id: A0A1B1SBL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1796646:A4V02 RS11030
gene id: 1796646:A4V02_RS11030
uniprot id: A0A1B1SBL0
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1796646:A4V02 RS05265
gene id: 1796646:A4V02_RS05265
uniprot id: A0A1B1S8Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1796646:A4V02 RS11150
gene id: 1796646:A4V02_RS11150
uniprot id: A0A1V0QE49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1796646:A4V02 RS01650
gene id: 1796646:A4V02_RS01650
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS02530
gene id: 1796646:A4V02_RS02530
uniprot id: A0A1B1S7C8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1796646:A4V02 RS07755
gene id: 1796646:A4V02_RS07755
uniprot id: A0A1B1S9Z0
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1796646:A4V02 RS05400
gene id: 1796646:A4V02_RS05400
uniprot id: A0A1B1S8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1796646:A4V02 RS04060
gene id: 1796646:A4V02_RS04060
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS05890
gene id: 1796646:A4V02_RS05890
uniprot id: A0A1B1S918
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS02350
gene id: 1796646:A4V02_RS02350
uniprot id: A0A1B1S792
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796646:A4V02 RS13145
gene id: 1796646:A4V02_RS13145
uniprot id: A0A1B1SCK3
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS10400
gene id: 1796646:A4V02_RS10400
uniprot id: A0A1B1SB86
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1796646:A4V02 RS09085
gene id: 1796646:A4V02_RS09085
uniprot id: A0A1B1SDC8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1796646:A4V02 RS10360
gene id: 1796646:A4V02_RS10360
uniprot id: A0A1B1SB85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1796646:A4V02 RS10860
gene id: 1796646:A4V02_RS10860
uniprot id: A0A1B1SBE5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1796646:A4V02 RS10655
gene id: 1796646:A4V02_RS10655
uniprot id: A0A1B1SDG8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1796646:A4V02 RS02275
gene id: 1796646:A4V02_RS02275
uniprot id: A0A1B1S793
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1796646:A4V02 RS10905
gene id: 1796646:A4V02_RS10905
uniprot id: A0A1B1SBF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1796646:A4V02 RS02725
gene id: 1796646:A4V02_RS02725
uniprot id: A0A1B1S7G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1796646:A4V02 RS06620
gene id: 1796646:A4V02_RS06620
uniprot id: A0A1B1S9D7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1796646:A4V02 RS10560
gene id: 1796646:A4V02_RS10560
uniprot id: A0A1B1SBB2
names: Similarity
messages: Belongs to the peptidase M24B family.

1796646:A4V02 RS07135
gene id: 1796646:A4V02_RS07135
uniprot id: A0A1B1S9P6
names: Similarity
messages: Belongs to the fabD family.

1796646:A4V02 RS12035
gene id: 1796646:A4V02_RS12035
uniprot id: A0A1B1SBZ2
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1796646:A4V02 RS11145
gene id: 1796646:A4V02_RS11145
uniprot id: A0A1B1SBN1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1796646:A4V02 RS13310
gene id: 1796646:A4V02_RS13310
uniprot id: A0A1B1SCR2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796646:A4V02 RS09815
gene id: 1796646:A4V02_RS09815
uniprot id: A0A1B1SAZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1796646:A4V02 RS04980
gene id: 1796646:A4V02_RS04980
uniprot id: A0A1B1S8J5
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS10250
gene id: 1796646:A4V02_RS10250
uniprot id: A0A1B1SB58
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1796646:A4V02 RS11545
gene id: 1796646:A4V02_RS11545
uniprot id: A0A1B1SBR0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1796646:A4V02 RS04415
gene id: 1796646:A4V02_RS04415
uniprot id: A0A1B1S892
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1796646:A4V02 RS11745
gene id: 1796646:A4V02_RS11745
uniprot id: A0A1B1SBV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1796646:A4V02 RS09940
gene id: 1796646:A4V02_RS09940
uniprot id: A0A1B1SB15
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1796646:A4V02 RS11200
gene id: 1796646:A4V02_RS11200
uniprot id: A0A1B1SBN5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1796646:A4V02 RS10490
gene id: 1796646:A4V02_RS10490
uniprot id: A0A1B1SBA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1796646:A4V02 RS02965
gene id: 1796646:A4V02_RS02965
uniprot id: A0A1B1S7K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1796646:A4V02 RS09425
gene id: 1796646:A4V02_RS09425
uniprot id: A0A1B1SAT2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1796646:A4V02 RS07295
gene id: 1796646:A4V02_RS07295
uniprot id: A0A1B1S9S3
names: Similarity
messages: Belongs to the YciI family.

1796646:A4V02 RS10720
gene id: 1796646:A4V02_RS10720
uniprot id: A0A1B1SBG7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1796646:A4V02 RS04750
gene id: 1796646:A4V02_RS04750
uniprot id: A0A1B1S8E3
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS01335
gene id: 1796646:A4V02_RS01335
uniprot id: A0A1B1S6T8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS00355
gene id: 1796646:A4V02_RS00355
uniprot id: A0A1B1S6D2
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1796646:A4V02 RS07435
gene id: 1796646:A4V02_RS07435
uniprot id: A0A1B1S9T7
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1796646:A4V02 RS12880
gene id: 1796646:A4V02_RS12880
uniprot id: A0A1B1SCL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1796646:A4V02 RS13090
gene id: 1796646:A4V02_RS13090
uniprot id: A0A1B1SCI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

1796646:A4V02 RS06915
gene id: 1796646:A4V02_RS06915
uniprot id: A0A1B1S9K5
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1796646:A4V02 RS10885
gene id: 1796646:A4V02_RS10885
uniprot id: A0A1B1SBD8
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS11440
gene id: 1796646:A4V02_RS11440
uniprot id: A0A1B1SBN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1796646:A4V02 RS08640
gene id: 1796646:A4V02_RS08640
uniprot id: A0A1B1SAD7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1796646:A4V02 RS13245
gene id: 1796646:A4V02_RS13245
uniprot id: A0A1B1SCN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS09605
gene id: 1796646:A4V02_RS09605
uniprot id: A0A1B1SAV4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1796646:A4V02 RS10950
gene id: 1796646:A4V02_RS10950
uniprot id: A0A4S2G440
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1796646:A4V02 RS10425
gene id: 1796646:A4V02_RS10425
uniprot id: A0A1B1SDB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1796646:A4V02 RS04275
gene id: 1796646:A4V02_RS04275
uniprot id: A0A1B1S874
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS12485
gene id: 1796646:A4V02_RS12485
uniprot id: A0A1B1SC75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1796646:A4V02 RS02700
gene id: 1796646:A4V02_RS02700
uniprot id: A0A1B1S7F8
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1796646:A4V02 RS09995
gene id: 1796646:A4V02_RS09995
uniprot id: A0A1B1SB25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1796646:A4V02 RS11040
gene id: 1796646:A4V02_RS11040
uniprot id: A0A1B1SBM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1796646:A4V02 RS12255
gene id: 1796646:A4V02_RS12255
uniprot id: A0A1B1SC70
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1796646:A4V02 RS10385
gene id: 1796646:A4V02_RS10385
uniprot id: A0A1B1SBB0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1796646:A4V02 RS09200
gene id: 1796646:A4V02_RS09200
uniprot id: A0A1B1SAP4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1796646:A4V02 RS02465
gene id: 1796646:A4V02_RS02465
uniprot id: A0A1B1S7B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1796646:A4V02 RS13425
gene id: 1796646:A4V02_RS13425
uniprot id: A0A1B1SCT6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1796646:A4V02 RS00850
gene id: 1796646:A4V02_RS00850
uniprot id: A0A1B1S6K3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1796646:A4V02 RS05520
gene id: 1796646:A4V02_RS05520
uniprot id: A0A1B1S8V7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1796646:A4V02 RS01750
gene id: 1796646:A4V02_RS01750
uniprot id: A0A1V0QEG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1796646:A4V02 RS00425
gene id: 1796646:A4V02_RS00425
uniprot id: A0A1B1S6E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

1796646:A4V02 RS02255
gene id: 1796646:A4V02_RS02255
uniprot id: A0A1B1S794
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS05215
gene id: 1796646:A4V02_RS05215
uniprot id: A0A1B1S8P2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1796646:A4V02 RS10880
gene id: 1796646:A4V02_RS10880
uniprot id: A0A1B1SBJ6
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS06385
gene id: 1796646:A4V02_RS06385
uniprot id: A0A1B1S9A6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1796646:A4V02 RS02785
gene id: 1796646:A4V02_RS02785
uniprot id: A0A1B1S7H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1796646:A4V02 RS13325
gene id: 1796646:A4V02_RS13325
uniprot id: A0A1B1SD48
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS00095
gene id: 1796646:A4V02_RS00095
uniprot id: A0A1B1S679
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1796646:A4V02 RS13000
gene id: 1796646:A4V02_RS13000
uniprot id: A0A1B1SCJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1796646:A4V02 RS09040
gene id: 1796646:A4V02_RS09040
uniprot id: A0A1B1SAL0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1796646:A4V02 RS10065
gene id: 1796646:A4V02_RS10065
uniprot id: A0A1B1SB30
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS03690
gene id: 1796646:A4V02_RS03690
uniprot id: A0A1B1S7Y8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1796646:A4V02 RS13455
gene id: 1796646:A4V02_RS13455
uniprot id: A0A1B1SCR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1796646:A4V02 RS00335
gene id: 1796646:A4V02_RS00335
uniprot id: A0A1V0QE27
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS01060
gene id: 1796646:A4V02_RS01060
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS07525
gene id: 1796646:A4V02_RS07525
uniprot id: A0A1B1S9U5
names: Similarity
messages: Belongs to the peptidase M16 family.

1796646:A4V02 RS12970
gene id: 1796646:A4V02_RS12970
uniprot id: A0A1B1SCI4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1796646:A4V02 RS07140
gene id: 1796646:A4V02_RS07140
uniprot id: A0A1B1S9M1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1796646:A4V02 RS08225
gene id: 1796646:A4V02_RS08225
uniprot id: A0A1B1SA58
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS05960
gene id: 1796646:A4V02_RS05960
uniprot id: A0A1B1S930
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1796646:A4V02 RS06400
gene id: 1796646:A4V02_RS06400
uniprot id: A0A1B1S9B5
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS12785
gene id: 1796646:A4V02_RS12785
uniprot id: A0A1B1SCH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1796646:A4V02 RS08335
gene id: 1796646:A4V02_RS08335
uniprot id: A0A1B1SAA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1796646:A4V02 RS03365
gene id: 1796646:A4V02_RS03365
uniprot id: A0A1B1S7S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1796646:A4V02 RS00400
gene id: 1796646:A4V02_RS00400
uniprot id: A0A1B1S6D1
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1796646:A4V02 RS04860
gene id: 1796646:A4V02_RS04860
uniprot id: A0A1B1S8G8
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1796646:A4V02 RS03060
gene id: 1796646:A4V02_RS03060
uniprot id: A0A1B1S7M1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796646:A4V02 RS00875
gene id: 1796646:A4V02_RS00875
uniprot id: A0A1B1S6L9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1796646:A4V02 RS13620
gene id: 1796646:A4V02_RS13620
uniprot id: A0A1B1SCS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1796646:A4V02 RS11420
gene id: 1796646:A4V02_RS11420
uniprot id: A0A1B1SBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS01745
gene id: 1796646:A4V02_RS01745
uniprot id: A0A1B1SD18
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS00475
gene id: 1796646:A4V02_RS00475
uniprot id: A0A1B1S6F1
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS03160
gene id: 1796646:A4V02_RS03160
uniprot id: A0A1B1S7P2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1796646:A4V02 RS09880
gene id: 1796646:A4V02_RS09880
uniprot id: A0A1B1SB01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1796646:A4V02 RS10475
gene id: 1796646:A4V02_RS10475
uniprot id: A0A1B1SB97
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1796646:A4V02 RS00855
gene id: 1796646:A4V02_RS00855
uniprot id: A0A1B1S6K8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1796646:A4V02 RS01435
gene id: 1796646:A4V02_RS01435
uniprot id: A0A1B1S6V0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1796646:A4V02 RS06785
gene id: 1796646:A4V02_RS06785
uniprot id: A0A1B1S9G7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1796646:A4V02 RS04195
gene id: 1796646:A4V02_RS04195
uniprot id: A0A1B1S861
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1796646:A4V02 RS06775
gene id: 1796646:A4V02_RS06775
uniprot id: A0A1B1S9I4
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1796646:A4V02 RS11620
gene id: 1796646:A4V02_RS11620
uniprot id: A0A1B1SBW9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1796646:A4V02 RS01545
gene id: 1796646:A4V02_RS01545
uniprot id: A0A1B1S6X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1796646:A4V02 RS02615
gene id: 1796646:A4V02_RS02615
uniprot id: A0A1B1S7E2
names: Similarity
messages: Belongs to the aldose epimerase family.

1796646:A4V02 RS11415
gene id: 1796646:A4V02_RS11415
uniprot id: A0A1B1SBT0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS09870
gene id: 1796646:A4V02_RS09870
uniprot id: A0A1B1SDB6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1796646:A4V02 RS11250
gene id: 1796646:A4V02_RS11250
uniprot id: A0A1B1SBP0
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS00535
gene id: 1796646:A4V02_RS00535
uniprot id: A0A1B1S6F5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1796646:A4V02 RS03015
gene id: 1796646:A4V02_RS03015
uniprot id: A0A1B1S7L5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1796646:A4V02 RS04340
gene id: 1796646:A4V02_RS04340
uniprot id: A0A1B1S895
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1796646:A4V02 RS01775
gene id: 1796646:A4V02_RS01775
uniprot id: A0A1B1S718
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1796646:A4V02 RS11425
gene id: 1796646:A4V02_RS11425
uniprot id: A0A1B1SBS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1796646:A4V02 RS04865
gene id: 1796646:A4V02_RS04865
uniprot id: A0A1B1S8H9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1796646:A4V02 RS08700
gene id: 1796646:A4V02_RS08700
uniprot id: A0A1B1SAE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS07910
gene id: 1796646:A4V02_RS07910
uniprot id: A0A1B1SA15
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1796646:A4V02 RS09125
gene id: 1796646:A4V02_RS09125
uniprot id: A0A1B1SDE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1796646:A4V02 RS12780
gene id: 1796646:A4V02_RS12780
uniprot id: A0A1B1SCH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796646:A4V02 RS07440
gene id: 1796646:A4V02_RS07440
uniprot id: A0A1B1S9T9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1796646:A4V02 RS01780
gene id: 1796646:A4V02_RS01780
uniprot id: A0A1B1S707
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1796646:A4V02 RS09630
gene id: 1796646:A4V02_RS09630
uniprot id: A0A1B1SAW0
names: Similarity
messages: Belongs to the asparaginase 1 family.

1796646:A4V02 RS08830
gene id: 1796646:A4V02_RS08830
uniprot id: A0A1B1SAH8
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS09265
gene id: 1796646:A4V02_RS09265
uniprot id: A0A1B1SAQ2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1796646:A4V02 RS08390
gene id: 1796646:A4V02_RS08390
uniprot id: A0A1B1SA89
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS01350
gene id: 1796646:A4V02_RS01350
uniprot id: A0A1B1S6U3
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1796646:A4V02 RS08725
gene id: 1796646:A4V02_RS08725
uniprot id: A0A1B1SAF1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS13545
gene id: 1796646:A4V02_RS13545
uniprot id: A0A1B1SCS8
names: Similarity
messages: Belongs to the Skp family.

1796646:A4V02 RS02525
gene id: 1796646:A4V02_RS02525
uniprot id: A0A1B1S7C4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1796646:A4V02 RS13550
gene id: 1796646:A4V02_RS13550
uniprot id: A0A1B1SCS6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1796646:A4V02 RS01980
gene id: 1796646:A4V02_RS01980
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS00435
gene id: 1796646:A4V02_RS00435
uniprot id: A0A1B1S6D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1796646:A4V02 RS02910
gene id: 1796646:A4V02_RS02910
uniprot id: A0A1B1S7J4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1796646:A4V02 RS10405
gene id: 1796646:A4V02_RS10405
uniprot id: A0A1B1SB74
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS07745
gene id: 1796646:A4V02_RS07745
uniprot id: A0A1B1S9X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS10940
gene id: 1796646:A4V02_RS10940
uniprot id: A0A1B1SBE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1796646:A4V02 RS10630
gene id: 1796646:A4V02_RS10630
uniprot id: A0A1B1SBE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1796646:A4V02 RS05850
gene id: 1796646:A4V02_RS05850
uniprot id: A0A1B1S921
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1796646:A4V02 RS10550
gene id: 1796646:A4V02_RS10550
uniprot id: A0A1B1SBD1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1796646:A4V02 RS06605
gene id: 1796646:A4V02_RS06605
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS02090
gene id: 1796646:A4V02_RS02090
uniprot id: A0A1B1S767
names: Similarity
messages: Belongs to the ParB family.

1796646:A4V02 RS00925
gene id: 1796646:A4V02_RS00925
uniprot id: A0A1B1S6M4
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS13575
gene id: 1796646:A4V02_RS13575
uniprot id: A0A1B1SCW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1796646:A4V02 RS09115
gene id: 1796646:A4V02_RS09115
uniprot id: A0A1B1SAN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1796646:A4V02 RS10510
gene id: 1796646:A4V02_RS10510
uniprot id: A0A1B1SBA3
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS09710
gene id: 1796646:A4V02_RS09710
uniprot id: A0A1B1SAX5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1796646:A4V02 RS02665
gene id: 1796646:A4V02_RS02665
uniprot id: A0A1B1S7F4
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS06365
gene id: 1796646:A4V02_RS06365
uniprot id: A0A1B1S9B4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1796646:A4V02 RS00295
gene id: 1796646:A4V02_RS00295
uniprot id: A0A1B1SD19
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS05280
gene id: 1796646:A4V02_RS05280
uniprot id: A0A1B1S8Q7
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS06880
gene id: 1796646:A4V02_RS06880
uniprot id: A0A1B1S9J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1796646:A4V02 RS07945
gene id: 1796646:A4V02_RS07945
uniprot id: A0A1B1SA26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796646:A4V02 RS01000
gene id: 1796646:A4V02_RS01000
uniprot id: A0A1B1S6P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1796646:A4V02 RS10935
gene id: 1796646:A4V02_RS10935
uniprot id: A0A1B1SBK3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1796646:A4V02 RS12520
gene id: 1796646:A4V02_RS12520
uniprot id: A0A1B1SCK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1796646:A4V02 RS00985
gene id: 1796646:A4V02_RS00985
uniprot id: A0A1B1S6N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1796646:A4V02 RS10375
gene id: 1796646:A4V02_RS10375
uniprot id: A0A1B1SB83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1796646:A4V02 RS10395
gene id: 1796646:A4V02_RS10395
uniprot id: A0A1B1SB87
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1796646:A4V02 RS09650
gene id: 1796646:A4V02_RS09650
uniprot id: A0A1B1SAW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1796646:A4V02 RS07680
gene id: 1796646:A4V02_RS07680
uniprot id: A0A1B1S9W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

1796646:A4V02 RS05995
gene id: 1796646:A4V02_RS05995
uniprot id: A0A1B1SCY6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1796646:A4V02 RS01310
gene id: 1796646:A4V02_RS01310
uniprot id: A0A1B1S6T7
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS11870
gene id: 1796646:A4V02_RS11870
uniprot id: A0A1B1SBW5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1796646:A4V02 RS13510
gene id: 1796646:A4V02_RS13510
uniprot id: A0A1B1SCQ9
names: Similarity
messages: Belongs to the peptidase C40 family.

1796646:A4V02 RS09465
gene id: 1796646:A4V02_RS09465
uniprot id: A0A1B1SDD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1796646:A4V02 RS08545
gene id: 1796646:A4V02_RS08545
uniprot id: A0A1V0QE33
names: Similarity
messages: Belongs to the DEAD box helicase family.

1796646:A4V02 RS09450
gene id: 1796646:A4V02_RS09450
uniprot id: A0A1B1SAT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1796646:A4V02 RS10245
gene id: 1796646:A4V02_RS10245
uniprot id: A0A1B1SB63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1796646:A4V02 RS00030
gene id: 1796646:A4V02_RS00030
uniprot id: A0A1B1S670
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS07900
gene id: 1796646:A4V02_RS07900
uniprot id: A0A1B1SA10
names: Similarity
messages: Belongs to the peptidase C40 family.

1796646:A4V02 RS10105
gene id: 1796646:A4V02_RS10105
uniprot id: A0A1B1SB47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1796646:A4V02 RS12800
gene id: 1796646:A4V02_RS12800
uniprot id: A0A1B1SCQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1796646:A4V02 RS08570
gene id: 1796646:A4V02_RS08570
uniprot id: A0A1B1SDD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1796646:A4V02 RS07380
gene id: 1796646:A4V02_RS07380
uniprot id: A0A1B1SDB0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1796646:A4V02 RS10390
gene id: 1796646:A4V02_RS10390
uniprot id: A0A1B1SBB3
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1796646:A4V02 RS00010
gene id: 1796646:A4V02_RS00010
uniprot id: A0A1B1S664
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1796646:A4V02 RS10600
gene id: 1796646:A4V02_RS10600
uniprot id: A0A1B1SBB9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1796646:A4V02 RS04895
gene id: 1796646:A4V02_RS04895
uniprot id: A0A1B1S8H7
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1796646:A4V02 RS11140
gene id: 1796646:A4V02_RS11140
uniprot id: A0A1B1SBN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1796646:A4V02 RS09460
gene id: 1796646:A4V02_RS09460
uniprot id: A0A1B1SAT9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1796646:A4V02 RS11255
gene id: 1796646:A4V02_RS11255
uniprot id: A0A1B1SBP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1796646:A4V02 RS00740
gene id: 1796646:A4V02_RS00740
uniprot id: A0A1B1SCX8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1796646:A4V02 RS11075
gene id: 1796646:A4V02_RS11075
uniprot id: A0A1B1SBH5
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS10520
gene id: 1796646:A4V02_RS10520
uniprot id: A0A1B1SB91
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS00995
gene id: 1796646:A4V02_RS00995
uniprot id: A0A1B1S6P3
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1796646:A4V02 RS11890
gene id: 1796646:A4V02_RS11890
uniprot id: A0A1B1SC13
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1796646:A4V02 RS07530
gene id: 1796646:A4V02_RS07530
uniprot id: A0A1B1S9U3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796646:A4V02 RS11560
gene id: 1796646:A4V02_RS11560
uniprot id: A0A1B1SBV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1796646:A4V02 RS12050
gene id: 1796646:A4V02_RS12050
uniprot id: A0A1B1SC42
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS12295
gene id: 1796646:A4V02_RS12295
uniprot id: A0A1B1SC82
names: Similarity
messages: Belongs to the ribF family.

1796646:A4V02 RS05515
gene id: 1796646:A4V02_RS05515
uniprot id: A0A1B1S8U3
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

1796646:A4V02 RS12280
gene id: 1796646:A4V02_RS12280
uniprot id: A0A1B1SC30
names: Similarity
messages: Belongs to the DapB family.

1796646:A4V02 RS08055
gene id: 1796646:A4V02_RS08055
uniprot id: A0A1B1SA38
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1796646:A4V02 RS05295
gene id: 1796646:A4V02_RS05295
uniprot id: A0A1B1S8Q9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1796646:A4V02 RS02840
gene id: 1796646:A4V02_RS02840
uniprot id: A0A1B1S7I5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1796646:A4V02 RS08320
gene id: 1796646:A4V02_RS08320
uniprot id: A0A1B1SAB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1796646:A4V02 RS13530
gene id: 1796646:A4V02_RS13530
uniprot id: A0A1B1SCS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1796646:A4V02 RS10615
gene id: 1796646:A4V02_RS10615
uniprot id: A0A1B1SBB7
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

1796646:A4V02 RS02920
gene id: 1796646:A4V02_RS02920
uniprot id: A0A1B1S7K0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1796646:A4V02 RS00415
gene id: 1796646:A4V02_RS00415
uniprot id: A0A1B1S6E5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1796646:A4V02 RS13750
gene id: 1796646:A4V02_RS13750
uniprot id: A0A1B1SCZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1796646:A4V02 RS11025
gene id: 1796646:A4V02_RS11025
uniprot id: A0A1B1SDN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1796646:A4V02 RS08300
gene id: 1796646:A4V02_RS08300
uniprot id: A0A1B1SA74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1796646:A4V02 RS12745
gene id: 1796646:A4V02_RS12745
uniprot id: A0A1B1SCE4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS08530
gene id: 1796646:A4V02_RS08530
uniprot id: A0A1B1SAD8
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1796646:A4V02 RS08205
gene id: 1796646:A4V02_RS08205
uniprot id: A0A1B1SA90
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS12825
gene id: 1796646:A4V02_RS12825
uniprot id: A0A1B1SCD6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1796646:A4V02 RS07955
gene id: 1796646:A4V02_RS07955
uniprot id: A0A1B1SA27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1796646:A4V02 RS00790
gene id: 1796646:A4V02_RS00790
uniprot id: A0A1B1S6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1796646:A4V02 RS00005
gene id: 1796646:A4V02_RS00005
uniprot id: A0A1B1SCX3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1796646:A4V02 RS13500
gene id: 1796646:A4V02_RS13500
uniprot id: A0A1B1SCR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1796646:A4V02 RS12670
gene id: 1796646:A4V02_RS12670
uniprot id: A0A1B1SCF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1796646:A4V02 RS06810
gene id: 1796646:A4V02_RS06810
uniprot id: A0A1B1S9H2
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1796646:A4V02 RS09480
gene id: 1796646:A4V02_RS09480
uniprot id: A0A1B1SAT7
names: Similarity
messages: Belongs to the AIR synthase family.

1796646:A4V02 RS08895
gene id: 1796646:A4V02_RS08895
uniprot id: A0A1B1SAI8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1796646:A4V02 RS10305
gene id: 1796646:A4V02_RS10305
uniprot id: A0A1B1SB68
names: Similarity
messages: Belongs to the RecJ family.

1796646:A4V02 RS11180
gene id: 1796646:A4V02_RS11180
uniprot id: A0A1B1SBK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS09380
gene id: 1796646:A4V02_RS09380
uniprot id: A0A1B1SAR8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1796646:A4V02 RS07770
gene id: 1796646:A4V02_RS07770
uniprot id: A0A1B1S9Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1796646:A4V02 RS02735
gene id: 1796646:A4V02_RS02735
uniprot id: A0A1B1S7H0
names: Subcellular Location Annotation
messages: Cytoplasm

1796646:A4V02 RS00885
gene id: 1796646:A4V02_RS00885
uniprot id: A0A1B1SD27
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1796646:A4V02 RS12885
gene id: 1796646:A4V02_RS12885
uniprot id: A0A1B1SCJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1796646:A4V02 RS04820
gene id: 1796646:A4V02_RS04820
uniprot id: A0A1B1S8G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1796646:A4V02 RS02950
gene id: 1796646:A4V02_RS02950
uniprot id: A0A1B1S7K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1796646:A4V02 RS06435
gene id: 1796646:A4V02_RS06435
uniprot id: A0A1Z2XJC2
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS01025
gene id: 1796646:A4V02_RS01025
uniprot id: A0A1B1S6N4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1796646:A4V02 RS12000
gene id: 1796646:A4V02_RS12000
uniprot id: A0A1B1SC37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1796646:A4V02 RS07610
gene id: 1796646:A4V02_RS07610
uniprot id: A0A1B1S9W3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1796646:A4V02 RS10500
gene id: 1796646:A4V02_RS10500
uniprot id: A0A1B1SBC5
names: Similarity
messages: Belongs to the DapA family.

1796646:A4V02 RS01520
gene id: 1796646:A4V02_RS01520
uniprot id: A0A1B1S6W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1796646:A4V02 RS11015
gene id: 1796646:A4V02_RS11015
uniprot id: A0A1B1SBH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1796646:A4V02 RS11955
gene id: 1796646:A4V02_RS11955
uniprot id: A0A1B1SC35
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1796646:A4V02 RS04810
gene id: 1796646:A4V02_RS04810
uniprot id: A0A1B1S8H2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1796646:A4V02 RS05285
gene id: 1796646:A4V02_RS05285
uniprot id: A0A1B1S8P8
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

1796646:A4V02 RS11520
gene id: 1796646:A4V02_RS11520
uniprot id: A0A1B1SBU9
names: Similarity
messages: Belongs to the SusD family.

1796646:A4V02 RS04205
gene id: 1796646:A4V02_RS04205
uniprot id: A0A1B1S857
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1796646:A4V02 RS11570
gene id: 1796646:A4V02_RS11570
uniprot id: A0A1B1SBV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

1796646:A4V02 RS10800
gene id: 1796646:A4V02_RS10800
uniprot id: A0A1B1SBE2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1796646:A4V02 RS02280
gene id: 1796646:A4V02_RS02280
uniprot id: A0A1B1S780
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1796646:A4V02 RS07115
gene id: 1796646:A4V02_RS07115
uniprot id: A0A1B1S9M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1796646:A4V02 RS00120
gene id: 1796646:A4V02_RS00120
uniprot id: A0A1B1S694
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1796646:A4V02 RS13200
gene id: 1796646:A4V02_RS13200
uniprot id: A0A1B1SDG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1796646:A4V02 RS10240
gene id: 1796646:A4V02_RS10240
uniprot id: A0A1B1SB67
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1796646:A4V02 RS05945
gene id: 1796646:A4V02_RS05945
uniprot id: A0A1B1S925
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1796646:A4V02 RS08230
gene id: 1796646:A4V02_RS08230
uniprot id: A0A1B1SA71
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1796646:A4V02 RS12975
gene id: 1796646:A4V02_RS12975
uniprot id: A0A1B1SCG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1796646:A4V02 RS03400
gene id: 1796646:A4V02_RS03400
uniprot id: A0A1B1S7S6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1796646:A4V02 RS12915
gene id: 1796646:A4V02_RS12915
uniprot id: A0A1B1SCG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1796646:A4V02 RS12460
gene id: 1796646:A4V02_RS12460
uniprot id: A0A1B1SCB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1796646:A4V02 RS02875
gene id: 1796646:A4V02_RS02875
uniprot id: A0A1B1S7I6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1796646:A4V02 RS08965
gene id: 1796646:A4V02_RS08965
uniprot id: A0A1B1SAJ8
names: Subcellular Location Annotation
messages: Membrane

1796646:A4V02 RS05140
gene id: 1796646:A4V02_RS05140
uniprot id: A0A1B1S8M4
names: Similarity
messages: Belongs to the UPF0102 family.

1796646:A4V02 RS10670
gene id: 1796646:A4V02_RS10670
uniprot id: A0A1B1SDD2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS00105
gene id: 1796646:A4V02_RS00105
uniprot id: A0A1B1SCW6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1796646:A4V02 RS04100
gene id: 1796646:A4V02_RS04100
uniprot id: A0A1B1S843
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1796646:A4V02 RS05895
gene id: 1796646:A4V02_RS05895
uniprot id: A0A1B1S914
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1796646:A4V02 RS08440
gene id: 1796646:A4V02_RS08440
uniprot id: A0A1B1SAA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1796646:A4V02 RS11325
gene id: 1796646:A4V02_RS11325
uniprot id: A0A1B1SBQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1796646:A4V02 RS01475
gene id: 1796646:A4V02_RS01475
uniprot id: A0A1B1SCZ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1796646:A4V02 RS04220
gene id: 1796646:A4V02_RS04220
uniprot id: A0A1B1S859
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1796646:A4V02 RS01690
gene id: 1796646:A4V02_RS01690
uniprot id: A0A1B1S6Z4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1796646:A4V02 RS05455
gene id: 1796646:A4V02_RS05455
uniprot id: A0A1B1S8T1
names: Similarity
messages: Belongs to the FBPase class 3 family.