1790137:AXE80 RS11465
gene id: 1790137:AXE80_RS11465
uniprot id: A0A1B1Y800
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1790137:AXE80 RS11155
gene id: 1790137:AXE80_RS11155
uniprot id: A0A1B1Y7T7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1790137:AXE80 RS05000
gene id: 1790137:AXE80_RS05000
uniprot id: A0A1B1Y4K3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1790137:AXE80 RS09535
gene id: 1790137:AXE80_RS09535
uniprot id: A0A1B1Y6Y2
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS03975
gene id: 1790137:AXE80_RS03975
uniprot id: A0A1B1Y3Z0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1790137:AXE80 RS08135
gene id: 1790137:AXE80_RS08135
uniprot id: A0A1B1Y640
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS01470
gene id: 1790137:AXE80_RS01470
uniprot id: A0A1B1Y2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1790137:AXE80 RS00870
gene id: 1790137:AXE80_RS00870
uniprot id: A0A1B1Y2D6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1790137:AXE80 RS02225
gene id: 1790137:AXE80_RS02225
uniprot id: A0A1B1Y327
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1790137:AXE80 RS00740
gene id: 1790137:AXE80_RS00740
uniprot id: A0A1B1Y2D9
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS03105
gene id: 1790137:AXE80_RS03105
uniprot id: A0A1B1Y3I3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1790137:AXE80 RS13685
gene id: 1790137:AXE80_RS13685
uniprot id: A0A1B1Y946
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1790137:AXE80 RS11375
gene id: 1790137:AXE80_RS11375
uniprot id: A0A1B1Y7T6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1790137:AXE80 RS06140
gene id: 1790137:AXE80_RS06140
uniprot id: A0A1B1Y521
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS13015
gene id: 1790137:AXE80_RS13015
uniprot id: A0A1B1Y8Q0
names: Caution
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1790137:AXE80 RS13885
gene id: 1790137:AXE80_RS13885
uniprot id: A0A1B1Y957
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1790137:AXE80 RS03055
gene id: 1790137:AXE80_RS03055
uniprot id: A0A1B1Y3H1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1790137:AXE80 RS03765
gene id: 1790137:AXE80_RS03765
uniprot id: A0A1B1Y3X8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1790137:AXE80 RS03210
gene id: 1790137:AXE80_RS03210
uniprot id: A0A1B1Y3K5
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS08965
gene id: 1790137:AXE80_RS08965
uniprot id: A0A1B1Y6M4
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1790137:AXE80 RS03145
gene id: 1790137:AXE80_RS03145
uniprot id: A0A1B1Y3J7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1790137:AXE80 RS02510
gene id: 1790137:AXE80_RS02510
uniprot id: A0A1B1Y378
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1790137:AXE80 RS03035
gene id: 1790137:AXE80_RS03035
uniprot id: A0A1B1Y3G2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS10550
gene id: 1790137:AXE80_RS10550
uniprot id: A0A1B1Y7C7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1790137:AXE80 RS00050
gene id: 1790137:AXE80_RS00050
uniprot id: A0A1B1Y1Z1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1790137:AXE80 RS01245
gene id: 1790137:AXE80_RS01245
uniprot id: A0A1B1Y2N8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1790137:AXE80 RS00715
gene id: 1790137:AXE80_RS00715
uniprot id: A0A1B1Y2A6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1790137:AXE80 RS07055
gene id: 1790137:AXE80_RS07055
uniprot id: A0A1B1Y5J1
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS00575
gene id: 1790137:AXE80_RS00575
uniprot id: A0A1B1Y2A9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1790137:AXE80 RS03000
gene id: 1790137:AXE80_RS03000
uniprot id: A0A1B1Y3G4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1790137:AXE80 RS14195
gene id: 1790137:AXE80_RS14195
uniprot id: A0A1B1Y9B6
names: Similarity
messages: Belongs to the DprA/Smf family.

1790137:AXE80 RS13850
gene id: 1790137:AXE80_RS13850
uniprot id: A0A1B1Y976
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS10420
gene id: 1790137:AXE80_RS10420
uniprot id: A0A1B1Y7E3
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1790137:AXE80 RS09970
gene id: 1790137:AXE80_RS09970
uniprot id: A0A1B1Y723
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1790137:AXE80 RS11630
gene id: 1790137:AXE80_RS11630
uniprot id: A0A1B1Y7Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1790137:AXE80 RS02535
gene id: 1790137:AXE80_RS02535
uniprot id: A0A1B1Y3B1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1790137:AXE80 RS00655
gene id: 1790137:AXE80_RS00655
uniprot id: A0A1B1Y295
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1790137:AXE80 RS11455
gene id: 1790137:AXE80_RS11455
uniprot id: A0A1B1Y7W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1790137:AXE80 RS09965
gene id: 1790137:AXE80_RS09965
uniprot id: A0A1B1Y724
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1790137:AXE80 RS05400
gene id: 1790137:AXE80_RS05400
uniprot id: A0A1B1Y4N8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1790137:AXE80 RS07635
gene id: 1790137:AXE80_RS07635
uniprot id: A0A1B1Y5W3
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS00680
gene id: 1790137:AXE80_RS00680
uniprot id: A0A1B1Y298
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1790137:AXE80 RS04985
gene id: 1790137:AXE80_RS04985
uniprot id: A0A1B1Y4G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1790137:AXE80 RS02035
gene id: 1790137:AXE80_RS02035
uniprot id: A0A1B1Y320
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1790137:AXE80 RS06230
gene id: 1790137:AXE80_RS06230
uniprot id: A0A1B1Y582
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1790137:AXE80 RS01755
gene id: 1790137:AXE80_RS01755
uniprot id: A0A1B1Y2X1
names: Similarity
messages: Belongs to the SCO1/2 family.

1790137:AXE80 RS13040
gene id: 1790137:AXE80_RS13040
uniprot id: A0A1B1Y8P2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1790137:AXE80 RS11830
gene id: 1790137:AXE80_RS11830
uniprot id: A0A1B1Y841
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Required for cell division and gliding motility.

1790137:AXE80 RS00515
gene id: 1790137:AXE80_RS00515
uniprot id: A0A1B1Y263
names: Subcellular Location Annotation
messages: Cytoplasm

1790137:AXE80 RS07610
gene id: 1790137:AXE80_RS07610
uniprot id: A0A1B1Y5X5
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS07960
gene id: 1790137:AXE80_RS07960
uniprot id: A0A1B1Y608
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1790137:AXE80 RS04975
gene id: 1790137:AXE80_RS04975
uniprot id: A0A1B1Y4I8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1790137:AXE80 RS13900
gene id: 1790137:AXE80_RS13900
uniprot id: A0A1B1Y987
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1790137:AXE80 RS02465
gene id: 1790137:AXE80_RS02465
uniprot id: A0A1B1Y372
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1790137:AXE80 RS08520
gene id: 1790137:AXE80_RS08520
uniprot id: A0A1B1Y6C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS04980
gene id: 1790137:AXE80_RS04980
uniprot id: A0A1B1Y4G1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1790137:AXE80 RS12555
gene id: 1790137:AXE80_RS12555
uniprot id: A0A1B1Y8E6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1790137:AXE80 RS12400
gene id: 1790137:AXE80_RS12400
uniprot id: A0A1B1Y8B7
names: Similarity
messages: Belongs to the UPF0758 family.

1790137:AXE80 RS02945
gene id: 1790137:AXE80_RS02945
uniprot id: A0A1B1Y3F3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1790137:AXE80 RS00215
gene id: 1790137:AXE80_RS00215
uniprot id: A0A1B1Y238
names: Similarity
messages: Belongs to the ArsC family.

1790137:AXE80 RS01310
gene id: 1790137:AXE80_RS01310
uniprot id: A0A1B1Y2L6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1790137:AXE80 RS11480
gene id: 1790137:AXE80_RS11480
uniprot id: A0A1B1Y7V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1790137:AXE80 RS03185
gene id: 1790137:AXE80_RS03185
uniprot id: A0A1B1Y3L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1790137:AXE80 RS09930
gene id: 1790137:AXE80_RS09930
uniprot id: A0A1B1Y754
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1790137:AXE80 RS12035
gene id: 1790137:AXE80_RS12035
uniprot id: A0A1B1Y8A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1790137:AXE80 RS09950
gene id: 1790137:AXE80_RS09950
uniprot id: A0A1B1Y755
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS04990
gene id: 1790137:AXE80_RS04990
uniprot id: A0A1B1Y4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1790137:AXE80 RS04270
gene id: 1790137:AXE80_RS04270
uniprot id: A0A1B1Y449
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1790137:AXE80 RS01075
gene id: 1790137:AXE80_RS01075
uniprot id: A0A1B1Y2J3
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS04340
gene id: 1790137:AXE80_RS04340
uniprot id: A0A1B1Y9N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1790137:AXE80 RS00375
gene id: 1790137:AXE80_RS00375
uniprot id: A0A1B1Y245
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1790137:AXE80 RS00505
gene id: 1790137:AXE80_RS00505
uniprot id: A0A1B1Y267
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1790137:AXE80 RS13835
gene id: 1790137:AXE80_RS13835
uniprot id: A0A1B1Y9R4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1790137:AXE80 RS00905
gene id: 1790137:AXE80_RS00905
uniprot id: A0A1B1Y2H1
names: Similarity
messages: Belongs to the citrate synthase family.

1790137:AXE80 RS05635
gene id: 1790137:AXE80_RS05635
uniprot id: A0A1B1Y4V9
names: Similarity
messages: Belongs to the AHA1 family.

1790137:AXE80 RS01375
gene id: 1790137:AXE80_RS01375
uniprot id: A0A1B1Y2M1
names: Similarity
messages: Belongs to the MoaD family.

1790137:AXE80 RS13905
gene id: 1790137:AXE80_RS13905
uniprot id: A0A1B1Y965
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1790137:AXE80 RS02805
gene id: 1790137:AXE80_RS02805
uniprot id: A0A1B1Y3G9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1790137:AXE80 RS01265
gene id: 1790137:AXE80_RS01265
uniprot id: A0A1B1Y2K3
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1790137:AXE80 RS06300
gene id: 1790137:AXE80_RS06300
uniprot id: A0A1B1Y588
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS10705
gene id: 1790137:AXE80_RS10705
uniprot id: A0A1B1Y7F4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1790137:AXE80 RS03025
gene id: 1790137:AXE80_RS03025
uniprot id: A0A1B1Y3I6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1790137:AXE80 RS07875
gene id: 1790137:AXE80_RS07875
uniprot id: A0A1B1Y5Y9
names: Subunit
messages: Homodimer.

1790137:AXE80 RS12700
gene id: 1790137:AXE80_RS12700
uniprot id: A0A1B1Y8P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1790137:AXE80 RS08300
gene id: 1790137:AXE80_RS08300
uniprot id: A0A1B1Y674
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1790137:AXE80 RS12885
gene id: 1790137:AXE80_RS12885
uniprot id: A0A1B1Y8L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1790137:AXE80 RS04900
gene id: 1790137:AXE80_RS04900
uniprot id: A0A1B1Y4H8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1790137:AXE80 RS07930
gene id: 1790137:AXE80_RS07930
uniprot id: A0A1B1Y9L2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1790137:AXE80 RS02230
gene id: 1790137:AXE80_RS02230
uniprot id: A0A1B1Y330
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1790137:AXE80 RS12015
gene id: 1790137:AXE80_RS12015
uniprot id: A0A1B1Y847
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1790137:AXE80 RS05410
gene id: 1790137:AXE80_RS05410
uniprot id: A0A1B1Y4P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1790137:AXE80 RS13790
gene id: 1790137:AXE80_RS13790
uniprot id: A0A1B1Y945
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1790137:AXE80 RS04720
gene id: 1790137:AXE80_RS04720
uniprot id: A0A1B1Y4E5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1790137:AXE80 RS04905
gene id: 1790137:AXE80_RS04905
uniprot id: A0A1B1Y4F1
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1790137:AXE80 RS12650
gene id: 1790137:AXE80_RS12650
uniprot id: A0A1B1Y8H3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1790137:AXE80 RS11020
gene id: 1790137:AXE80_RS11020
uniprot id: A0A1B1Y7L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

1790137:AXE80 RS05065
gene id: 1790137:AXE80_RS05065
uniprot id: A0A1B1Y4H5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1790137:AXE80 RS01415
gene id: 1790137:AXE80_RS01415
uniprot id: A0A1B1Y2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapB family.
messages: Periplasm

1790137:AXE80 RS06520
gene id: 1790137:AXE80_RS06520
uniprot id: A0A1B1Y589
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1790137:AXE80 RS04085
gene id: 1790137:AXE80_RS04085
uniprot id: A0A1B1Y416
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS12355
gene id: 1790137:AXE80_RS12355
uniprot id: A0A1B1Y8C1
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS12615
gene id: 1790137:AXE80_RS12615
uniprot id: A0A1B1Y8J8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1790137:AXE80 RS02285
gene id: 1790137:AXE80_RS02285
uniprot id: A0A1B1Y370
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1790137:AXE80 RS08780
gene id: 1790137:AXE80_RS08780
uniprot id: A0A1B1Y6H0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1790137:AXE80 RS11490
gene id: 1790137:AXE80_RS11490
uniprot id: A0A1B1Y7W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1790137:AXE80 RS09510
gene id: 1790137:AXE80_RS09510
uniprot id: A0A1B1Y6V3
names: Similarity
messages: Belongs to the Dps family.

1790137:AXE80 RS09440
gene id: 1790137:AXE80_RS09440
uniprot id: A0A1B1Y6U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1790137:AXE80 RS00095
gene id: 1790137:AXE80_RS00095
uniprot id: A0A1B1Y9D2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1790137:AXE80 RS07830
gene id: 1790137:AXE80_RS07830
uniprot id: A0A1B1Y614
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS03355
gene id: 1790137:AXE80_RS03355
uniprot id: A0A1B1Y3M3
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS03885
gene id: 1790137:AXE80_RS03885
uniprot id: A0A1B1Y3Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1790137:AXE80 RS10015
gene id: 1790137:AXE80_RS10015
uniprot id: A0A1B1Y738
names: Similarity
messages: Belongs to the MQO family.

1790137:AXE80 RS06125
gene id: 1790137:AXE80_RS06125
uniprot id: A0A1B1Y565
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1790137:AXE80 RS05020
gene id: 1790137:AXE80_RS05020
uniprot id: A0A1B1Y4H4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1790137:AXE80 RS00835
gene id: 1790137:AXE80_RS00835
uniprot id: A0A1B1Y2C3
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1790137:AXE80 RS02675
gene id: 1790137:AXE80_RS02675
uniprot id: A0A1B1Y3B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1790137:AXE80 RS02725
gene id: 1790137:AXE80_RS02725
uniprot id: A0A1B1Y3C3
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS02305
gene id: 1790137:AXE80_RS02305
uniprot id: A0A1B1Y339
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1790137:AXE80 RS12380
gene id: 1790137:AXE80_RS12380
uniprot id: A0A1B1Y8I2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1790137:AXE80 RS05490
gene id: 1790137:AXE80_RS05490
uniprot id: A0A1B1Y4R0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS13170
gene id: 1790137:AXE80_RS13170
uniprot id: A0A1B1Y8U0
names: Similarity
messages: Belongs to the pyruvate kinase family.

1790137:AXE80 RS11535
gene id: 1790137:AXE80_RS11535
uniprot id: A0A1B1Y7W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1790137:AXE80 RS06575
gene id: 1790137:AXE80_RS06575
uniprot id: A0A1B1Y599
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1790137:AXE80 RS05015
gene id: 1790137:AXE80_RS05015
uniprot id: A0A1B1Y4G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1790137:AXE80 RS13470
gene id: 1790137:AXE80_RS13470
uniprot id: A0A1B1Y8Z1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1790137:AXE80 RS02325
gene id: 1790137:AXE80_RS02325
uniprot id: A0A1B1Y365
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS14205
gene id: 1790137:AXE80_RS14205
uniprot id: A0A1B1Y9E6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1790137:AXE80 RS06385
gene id: 1790137:AXE80_RS06385
uniprot id: A0A1B1Y568
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1790137:AXE80 RS12280
gene id: 1790137:AXE80_RS12280
uniprot id: A0A1B1Y8G5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1790137:AXE80 RS09490
gene id: 1790137:AXE80_RS09490
uniprot id: A0A1B1Y6V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1790137:AXE80 RS08335
gene id: 1790137:AXE80_RS08335
uniprot id: A0A1B1Y678
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1790137:AXE80 RS00200
gene id: 1790137:AXE80_RS00200
uniprot id: A0A1B1Y241
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS00020
gene id: 1790137:AXE80_RS00020
uniprot id: A0A1B1Y1Y6
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1790137:AXE80 RS14075
gene id: 1790137:AXE80_RS14075
uniprot id: A0A1B1Y9F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1790137:AXE80 RS06005
gene id: 1790137:AXE80_RS06005
uniprot id: A0A1B1Y541
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS13245
gene id: 1790137:AXE80_RS13245
uniprot id: A0A1B1Y8T3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1790137:AXE80 RS09375
gene id: 1790137:AXE80_RS09375
uniprot id: A0A1B1Y6V6
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS09920
gene id: 1790137:AXE80_RS09920
uniprot id: A0A1B1Y710
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1790137:AXE80 RS09855
gene id: 1790137:AXE80_RS09855
uniprot id: A0A1B1Y716
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1790137:AXE80 RS04730
gene id: 1790137:AXE80_RS04730
uniprot id: A0A1B1Y4C1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1790137:AXE80 RS08270
gene id: 1790137:AXE80_RS08270
uniprot id: A0A1B1Y679
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1790137:AXE80 RS10300
gene id: 1790137:AXE80_RS10300
uniprot id: A0A1B1Y7C3
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS13120
gene id: 1790137:AXE80_RS13120
uniprot id: A0A1B1Y8S7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1790137:AXE80 RS11550
gene id: 1790137:AXE80_RS11550
uniprot id: A0A1B1Y7Y2
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1790137:AXE80 RS09180
gene id: 1790137:AXE80_RS09180
uniprot id: A0A1B1Y6R4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1790137:AXE80 RS13225
gene id: 1790137:AXE80_RS13225
uniprot id: A0A1B1Y8T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1790137:AXE80 RS02795
gene id: 1790137:AXE80_RS02795
uniprot id: A0A1B1Y3F0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1790137:AXE80 RS11340
gene id: 1790137:AXE80_RS11340
uniprot id: A0A1B1Y7T4
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1790137:AXE80 RS09710
gene id: 1790137:AXE80_RS09710
uniprot id: A0A1B1Y6X6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1790137:AXE80 RS12215
gene id: 1790137:AXE80_RS12215
uniprot id: A0A1B1Y8A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1790137:AXE80 RS04000
gene id: 1790137:AXE80_RS04000
uniprot id: A0A1B1Y414
names: Similarity
messages: Belongs to the NusB family.

1790137:AXE80 RS06305
gene id: 1790137:AXE80_RS06305
uniprot id: A0A1B1Y580
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS02600
gene id: 1790137:AXE80_RS02600
uniprot id: A0A1B1Y3D2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1790137:AXE80 RS10580
gene id: 1790137:AXE80_RS10580
uniprot id: A0A1B1Y7E5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1790137:AXE80 RS10215
gene id: 1790137:AXE80_RS10215
uniprot id: A0A1B1Y7B5
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS01240
gene id: 1790137:AXE80_RS01240
uniprot id: A0A1B1Y2M4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS13010
gene id: 1790137:AXE80_RS13010
uniprot id: A0A1B1Y8R0
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS07465
gene id: 1790137:AXE80_RS07465
uniprot id: A0A1B1Y5Q8
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1790137:AXE80 RS13185
gene id: 1790137:AXE80_RS13185
uniprot id: A0A1B1Y8Y5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1790137:AXE80 RS01735
gene id: 1790137:AXE80_RS01735
uniprot id: A0A1B1Y2U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1790137:AXE80 RS05640
gene id: 1790137:AXE80_RS05640
uniprot id: A0A1B1Y4S9
names: Similarity
messages: Belongs to the AHA1 family.

1790137:AXE80 RS00085
gene id: 1790137:AXE80_RS00085
uniprot id: A0A1B1Y9C2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS05260
gene id: 1790137:AXE80_RS05260
uniprot id: A0A1B1Y4L2
names: Similarity
messages: Belongs to the SCO1/2 family.

1790137:AXE80 RS09070
gene id: 1790137:AXE80_RS09070
uniprot id: A0A1B1Y6L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1790137:AXE80 RS04860
gene id: 1790137:AXE80_RS04860
uniprot id: A0A1B1Y4E1
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1790137:AXE80 RS07890
gene id: 1790137:AXE80_RS07890
uniprot id: A0A1B1Y624
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1790137:AXE80 RS02610
gene id: 1790137:AXE80_RS02610
uniprot id: A0A1B1Y3A7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1790137:AXE80 RS06890
gene id: 1790137:AXE80_RS06890
uniprot id: A0A1B1Y9K0
names: Similarity
messages: Belongs to the HsdR family.

1790137:AXE80 RS12670
gene id: 1790137:AXE80_RS12670
uniprot id: A0A1B1Y8I0
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1790137:AXE80 RS12865
gene id: 1790137:AXE80_RS12865
uniprot id: A0A1B1Y8M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1790137:AXE80 RS02405
gene id: 1790137:AXE80_RS02405
uniprot id: A0A1B1Y357
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS07995
gene id: 1790137:AXE80_RS07995
uniprot id: A0A1B1Y643
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1790137:AXE80 RS11820
gene id: 1790137:AXE80_RS11820
uniprot id: A0A1B1Y853
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS11520
gene id: 1790137:AXE80_RS11520
uniprot id: A0A1B1Y807
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1790137:AXE80 RS05935
gene id: 1790137:AXE80_RS05935
uniprot id: A0A1B1Y4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS06700
gene id: 1790137:AXE80_RS06700
uniprot id: A0A1B1Y5E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS11115
gene id: 1790137:AXE80_RS11115
uniprot id: A0A1B1Y7N4
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS04325
gene id: 1790137:AXE80_RS04325
uniprot id: A0A1B1Y452
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1790137:AXE80 RS01620
gene id: 1790137:AXE80_RS01620
uniprot id: A0A1B1Y2S3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1790137:AXE80 RS07840
gene id: 1790137:AXE80_RS07840
uniprot id: A0A1B1Y5X8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1790137:AXE80 RS06895
gene id: 1790137:AXE80_RS06895
uniprot id: A0A1B1Y5G0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1790137:AXE80 RS12340
gene id: 1790137:AXE80_RS12340
uniprot id: A0A1B1Y8B4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1790137:AXE80 RS05265
gene id: 1790137:AXE80_RS05265
uniprot id: A0A1B1Y4Q4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS04030
gene id: 1790137:AXE80_RS04030
uniprot id: A0A1B1Y3Z9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS06625
gene id: 1790137:AXE80_RS06625
uniprot id: A0A1B1Y5D9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1790137:AXE80 RS06615
gene id: 1790137:AXE80_RS06615
uniprot id: A0A1B1Y5F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1790137:AXE80 RS12545
gene id: 1790137:AXE80_RS12545
uniprot id: A0A1B1Y8F7
names: Similarity
messages: Belongs to the arginase family.

1790137:AXE80 RS05005
gene id: 1790137:AXE80_RS05005
uniprot id: A0A1B1Y4K2
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS04870
gene id: 1790137:AXE80_RS04870
uniprot id: A0A1B1Y4I3
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS03020
gene id: 1790137:AXE80_RS03020
uniprot id: A0A1B1Y3K8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1790137:AXE80 RS14070
gene id: 1790137:AXE80_RS14070
uniprot id: A0A1B1Y9D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1790137:AXE80 RS05520
gene id: 1790137:AXE80_RS05520
uniprot id: A0A1B1Y4V8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1790137:AXE80 RS12335
gene id: 1790137:AXE80_RS12335
uniprot id: A0A1B1Y8H2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Heterotrimer of A, B and C subunits.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS08875
gene id: 1790137:AXE80_RS08875
uniprot id: A0A1B1NX89
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1790137:AXE80 RS14210
gene id: 1790137:AXE80_RS14210
uniprot id: A0A1B1Y9E9
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS06880
gene id: 1790137:AXE80_RS06880
uniprot id: A0A1B1Y5K1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1790137:AXE80 RS00390
gene id: 1790137:AXE80_RS00390
uniprot id: A0A1B1Y249
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1790137:AXE80 RS11955
gene id: 1790137:AXE80_RS11955
uniprot id: A0A1B1Y897
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1790137:AXE80 RS12910
gene id: 1790137:AXE80_RS12910
uniprot id: A0A1B1Y8N6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS06790
gene id: 1790137:AXE80_RS06790
uniprot id: A0A1B1Y5E2
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS08785
gene id: 1790137:AXE80_RS08785
uniprot id: A0A1B1Y6K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1790137:AXE80 RS11350
gene id: 1790137:AXE80_RS11350
uniprot id: A0A1B1Y7V6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1790137:AXE80 RS11845
gene id: 1790137:AXE80_RS11845
uniprot id: A0A1B1Y881
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1790137:AXE80 RS09960
gene id: 1790137:AXE80_RS09960
uniprot id: A0A1B1Y734
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1790137:AXE80 RS00825
gene id: 1790137:AXE80_RS00825
uniprot id: A0A1B1Y2D0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1790137:AXE80 RS11405
gene id: 1790137:AXE80_RS11405
uniprot id: A0A1B1Y7W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1790137:AXE80 RS03070
gene id: 1790137:AXE80_RS03070
uniprot id: A0A1B1Y3L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1790137:AXE80 RS11640
gene id: 1790137:AXE80_RS11640
uniprot id: A0A1B1Y7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1790137:AXE80 RS10440
gene id: 1790137:AXE80_RS10440
uniprot id: A0A1B1Y7A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS09650
gene id: 1790137:AXE80_RS09650
uniprot id: A0A1B1Y6W1
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1790137:AXE80 RS00380
gene id: 1790137:AXE80_RS00380
uniprot id: A0A1B1Y246
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1790137:AXE80 RS02320
gene id: 1790137:AXE80_RS02320
uniprot id: A0A1B1Y336
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1790137:AXE80 RS02020
gene id: 1790137:AXE80_RS02020
uniprot id: A0A1B1Y2Y3
names: Similarity
messages: Belongs to the peptidase S49 family.

1790137:AXE80 RS05105
gene id: 1790137:AXE80_RS05105
uniprot id: A0A1B1Y4M1
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS12755
gene id: 1790137:AXE80_RS12755
uniprot id: A0A1B1Y8P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS09195
gene id: 1790137:AXE80_RS09195
uniprot id: A0A1B1Y6P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1790137:AXE80 RS11415
gene id: 1790137:AXE80_RS11415
uniprot id: A0A1B1Y7Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1790137:AXE80 RS14060
gene id: 1790137:AXE80_RS14060
uniprot id: A0A1B1Y9B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

1790137:AXE80 RS00895
gene id: 1790137:AXE80_RS00895
uniprot id: A0A1B1Y2H0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1790137:AXE80 RS02495
gene id: 1790137:AXE80_RS02495
uniprot id: A0A1B1Y386
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1790137:AXE80 RS09530
gene id: 1790137:AXE80_RS09530
uniprot id: A0A1B1Y6W2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS04680
gene id: 1790137:AXE80_RS04680
uniprot id: A0A1B1Y4B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1790137:AXE80 RS11510
gene id: 1790137:AXE80_RS11510
uniprot id: A0A1B1Y7Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1790137:AXE80 RS07545
gene id: 1790137:AXE80_RS07545
uniprot id: A0A1B1Y5T0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS05270
gene id: 1790137:AXE80_RS05270
uniprot id: A0A1B1Y4Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1790137:AXE80 RS07570
gene id: 1790137:AXE80_RS07570
uniprot id: A0A1B1Y5S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1790137:AXE80 RS00610
gene id: 1790137:AXE80_RS00610
uniprot id: A0A1B1Y285
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1790137:AXE80 RS13930
gene id: 1790137:AXE80_RS13930
uniprot id: A0A1B1Y972
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1790137:AXE80 RS02430
gene id: 1790137:AXE80_RS02430
uniprot id: A0A1B1Y392
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1790137:AXE80 RS13130
gene id: 1790137:AXE80_RS13130
uniprot id: A0A1B1Y8W5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1790137:AXE80 RS00795
gene id: 1790137:AXE80_RS00795
uniprot id: A0A1B1Y2F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1790137:AXE80 RS13320
gene id: 1790137:AXE80_RS13320
uniprot id: A0A1B1Y8W9
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1790137:AXE80 RS14145
gene id: 1790137:AXE80_RS14145
uniprot id: A0A1B1Y9A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1790137:AXE80 RS12870
gene id: 1790137:AXE80_RS12870
uniprot id: A0A1B1Y8S1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1790137:AXE80 RS07650
gene id: 1790137:AXE80_RS07650
uniprot id: A0A1B1Y5W1
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

1790137:AXE80 RS03370
gene id: 1790137:AXE80_RS03370
uniprot id: A0A1B1Y3M7
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS09575
gene id: 1790137:AXE80_RS09575
uniprot id: A0A1B1Y6V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1790137:AXE80 RS01035
gene id: 1790137:AXE80_RS01035
uniprot id: A0A1B1Y2G7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1790137:AXE80 RS04505
gene id: 1790137:AXE80_RS04505
uniprot id: A0A1B1Y4A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS04710
gene id: 1790137:AXE80_RS04710
uniprot id: A0A1B1Y4E8
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS05300
gene id: 1790137:AXE80_RS05300
uniprot id: A0A1B1Y4L7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1790137:AXE80 RS00445
gene id: 1790137:AXE80_RS00445
uniprot id: A0A1B1Y258
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1790137:AXE80 RS11650
gene id: 1790137:AXE80_RS11650
uniprot id: A0A1B1Y837
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1790137:AXE80 RS02985
gene id: 1790137:AXE80_RS02985
uniprot id: A0A1B1Y3F2
names: Similarity
messages: Belongs to the HSP15 family.

1790137:AXE80 RS14135
gene id: 1790137:AXE80_RS14135
uniprot id: A0A1B1Y9A1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1790137:AXE80 RS13195
gene id: 1790137:AXE80_RS13195
uniprot id: A0A1B1Y8S4
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS12780
gene id: 1790137:AXE80_RS12780
uniprot id: A0A1B1Y8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS12810
gene id: 1790137:AXE80_RS12810
uniprot id: A0A1B1Y8Q6
names: Similarity
messages: Belongs to the NAD synthetase family.

1790137:AXE80 RS03455
gene id: 1790137:AXE80_RS03455
uniprot id: A0A1B1Y3S4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1790137:AXE80 RS10475
gene id: 1790137:AXE80_RS10475
uniprot id: A0A1B1Y7F1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1790137:AXE80 RS03540
gene id: 1790137:AXE80_RS03540
uniprot id: A0A1B1Y3Q9
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS05060
gene id: 1790137:AXE80_RS05060
uniprot id: A0A1B1Y4J8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1790137:AXE80 RS11530
gene id: 1790137:AXE80_RS11530
uniprot id: A0A1B1Y7W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1790137:AXE80 RS00280
gene id: 1790137:AXE80_RS00280
uniprot id: A0A1B1Y226
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1790137:AXE80 RS05445
gene id: 1790137:AXE80_RS05445
uniprot id: A0A1B1Y4S8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1790137:AXE80 RS03040
gene id: 1790137:AXE80_RS03040
uniprot id: A0A1B1Y3I2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1790137:AXE80 RS04555
gene id: 1790137:AXE80_RS04555
uniprot id: A0A1B1Y4B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1790137:AXE80 RS14100
gene id: 1790137:AXE80_RS14100
uniprot id: A0A1B1Y9C7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS09080
gene id: 1790137:AXE80_RS09080
uniprot id: A0A1B1Y6Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1790137:AXE80 RS05435
gene id: 1790137:AXE80_RS05435
uniprot id: A0A1B1Y4P3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1790137:AXE80 RS09010
gene id: 1790137:AXE80_RS09010
uniprot id: A0A1B1Y6L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1790137:AXE80 RS09260
gene id: 1790137:AXE80_RS09260
uniprot id: A0A1B1Y6R2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS00590
gene id: 1790137:AXE80_RS00590
uniprot id: A0A1B1Y2A4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS07975
gene id: 1790137:AXE80_RS07975
uniprot id: A0A1B1Y621
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS01640
gene id: 1790137:AXE80_RS01640
uniprot id: A0A1B1Y2S4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1790137:AXE80 RS08220
gene id: 1790137:AXE80_RS08220
uniprot id: A0A1B1Y657
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1790137:AXE80 RS13690
gene id: 1790137:AXE80_RS13690
uniprot id: A0A1B1Y928
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS09850
gene id: 1790137:AXE80_RS09850
uniprot id: A0A1B1Y737
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS00195
gene id: 1790137:AXE80_RS00195
uniprot id: A0A1B1Y211
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1790137:AXE80 RS06505
gene id: 1790137:AXE80_RS06505
uniprot id: A0A1B1Y5D0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1790137:AXE80 RS12575
gene id: 1790137:AXE80_RS12575
uniprot id: A0A1B1Y8I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1790137:AXE80 RS05240
gene id: 1790137:AXE80_RS05240
uniprot id: A0A1B1Y4L4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1790137:AXE80 RS09685
gene id: 1790137:AXE80_RS09685
uniprot id: A0A1B1Y706
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1790137:AXE80 RS04960
gene id: 1790137:AXE80_RS04960
uniprot id: A0A1B1Y4H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1790137:AXE80 RS00880
gene id: 1790137:AXE80_RS00880
uniprot id: A0A1B1Y2D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1790137:AXE80 RS09990
gene id: 1790137:AXE80_RS09990
uniprot id: A0A1B1Y742
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1790137:AXE80 RS12550
gene id: 1790137:AXE80_RS12550
uniprot id: A0A1B1Y9Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1790137:AXE80 RS08650
gene id: 1790137:AXE80_RS08650
uniprot id: A0A1B1Y6G9
names: Similarity
messages: Belongs to the BshC family.

1790137:AXE80 RS11440
gene id: 1790137:AXE80_RS11440
uniprot id: A0A1B1Y7Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1790137:AXE80 RS01180
gene id: 1790137:AXE80_RS01180
uniprot id: A0A1B1Y2I4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1790137:AXE80 RS00665
gene id: 1790137:AXE80_RS00665
uniprot id: A0A1B1Y294
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS04390
gene id: 1790137:AXE80_RS04390
uniprot id: A0A1B1Y489
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1790137:AXE80 RS11060
gene id: 1790137:AXE80_RS11060
uniprot id: A0A1B1Y7R4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1790137:AXE80 RS01255
gene id: 1790137:AXE80_RS01255
uniprot id: A0A1B1Y2K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1790137:AXE80 RS08050
gene id: 1790137:AXE80_RS08050
uniprot id: A0A1B1Y655
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS11395
gene id: 1790137:AXE80_RS11395
uniprot id: A0A1B1Y7U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1790137:AXE80 RS02935
gene id: 1790137:AXE80_RS02935
uniprot id: A0A1B1Y3G5
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS03990
gene id: 1790137:AXE80_RS03990
uniprot id: A0A1B1Y410
names: Subcellular Location Annotation
messages: Nucleus

1790137:AXE80 RS12080
gene id: 1790137:AXE80_RS12080
uniprot id: A0A1B1Y8B8
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1790137:AXE80 RS00990
gene id: 1790137:AXE80_RS00990
uniprot id: A0A1B1Y2F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1790137:AXE80 RS10030
gene id: 1790137:AXE80_RS10030
uniprot id: A0A1B1Y757
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1790137:AXE80 RS01160
gene id: 1790137:AXE80_RS01160
uniprot id: A0A1B1Y9D5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1790137:AXE80 RS11180
gene id: 1790137:AXE80_RS11180
uniprot id: A0A1B1Y7Q0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1790137:AXE80 RS11390
gene id: 1790137:AXE80_RS11390
uniprot id: A0A1B1Y7Y0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1790137:AXE80 RS09155
gene id: 1790137:AXE80_RS09155
uniprot id: A0A1B1Y6M7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1790137:AXE80 RS11815
gene id: 1790137:AXE80_RS11815
uniprot id: A0A1B1Y814
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1790137:AXE80 RS11380
gene id: 1790137:AXE80_RS11380
uniprot id: A0A1B1Y9Q8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1790137:AXE80 RS03665
gene id: 1790137:AXE80_RS03665
uniprot id: A0A1B1Y3T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1790137:AXE80 RS07430
gene id: 1790137:AXE80_RS07430
uniprot id: A0A1B1Y5U9
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS13460
gene id: 1790137:AXE80_RS13460
uniprot id: A0A1B1Y8X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS02330
gene id: 1790137:AXE80_RS02330
uniprot id: A0A1B1Y367
names: Similarity
messages: Belongs to the CarB family.

1790137:AXE80 RS11435
gene id: 1790137:AXE80_RS11435
uniprot id: A0A1B1Y7V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1790137:AXE80 RS09615
gene id: 1790137:AXE80_RS09615
uniprot id: A0A1B1Y6Z9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1790137:AXE80 RS11625
gene id: 1790137:AXE80_RS11625
uniprot id: A0A1B1Y832
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1790137:AXE80 RS04200
gene id: 1790137:AXE80_RS04200
uniprot id: A0A1B1Y460
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS12605
gene id: 1790137:AXE80_RS12605
uniprot id: A0A1B1Y8F8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1790137:AXE80 RS01740
gene id: 1790137:AXE80_RS01740
uniprot id: A0A1B1Y9G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1790137:AXE80 RS04240
gene id: 1790137:AXE80_RS04240
uniprot id: A0A1B1Y437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

1790137:AXE80 RS00500
gene id: 1790137:AXE80_RS00500
uniprot id: A0A1B1Y265
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1790137:AXE80 RS07970
gene id: 1790137:AXE80_RS07970
uniprot id: A0A1B1Y651
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS03625
gene id: 1790137:AXE80_RS03625
uniprot id: A0A1B1Y3R3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1790137:AXE80 RS07740
gene id: 1790137:AXE80_RS07740
uniprot id: A0A1B1Y5V8
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS09110
gene id: 1790137:AXE80_RS09110
uniprot id: A0A1B1Y6Q9
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1790137:AXE80 RS05125
gene id: 1790137:AXE80_RS05125
uniprot id: A0A1B1Y4M0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1790137:AXE80 RS02590
gene id: 1790137:AXE80_RS02590
uniprot id: A0A1B1Y3B0
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS12465
gene id: 1790137:AXE80_RS12465
uniprot id: A0A1B1Y8F4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS07405
gene id: 1790137:AXE80_RS07405
uniprot id: A0A1B1Y5S8
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS08450
gene id: 1790137:AXE80_RS08450
uniprot id: A0A1B1Y697
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1790137:AXE80 RS01515
gene id: 1790137:AXE80_RS01515
uniprot id: A0A1B1Y2Q4
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1790137:AXE80 RS00345
gene id: 1790137:AXE80_RS00345
uniprot id: A0A1B1Y235
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS06015
gene id: 1790137:AXE80_RS06015
uniprot id: A0A1B1Y542
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS07900
gene id: 1790137:AXE80_RS07900
uniprot id: A0A1B1Y5Y8
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1790137:AXE80 RS00965
gene id: 1790137:AXE80_RS00965
uniprot id: A0A1B1Y2H3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1790137:AXE80 RS02705
gene id: 1790137:AXE80_RS02705
uniprot id: A0A1B1Y3C6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS11335
gene id: 1790137:AXE80_RS11335
uniprot id: A0A1B1Y7X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1790137:AXE80 RS06765
gene id: 1790137:AXE80_RS06765
uniprot id: A0A1B1Y5I3
names: Similarity
messages: Belongs to the peptidase M1 family.

1790137:AXE80 RS09475
gene id: 1790137:AXE80_RS09475
uniprot id: A0A1B1Y6V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1790137:AXE80 RS10255
gene id: 1790137:AXE80_RS10255
uniprot id: A0A1B1Y768
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS09150
gene id: 1790137:AXE80_RS09150
uniprot id: A0A1B1Y6L8
names: Similarity
messages: Belongs to the UPF0047 family.

1790137:AXE80 RS11515
gene id: 1790137:AXE80_RS11515
uniprot id: A0A1B1Y812
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1790137:AXE80 RS01040
gene id: 1790137:AXE80_RS01040
uniprot id: A0A1B1Y2G9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1790137:AXE80 RS01550
gene id: 1790137:AXE80_RS01550
uniprot id: A0A1B1Y2V2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1790137:AXE80 RS05940
gene id: 1790137:AXE80_RS05940
uniprot id: A0A1B1Y4Z0
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS07905
gene id: 1790137:AXE80_RS07905
uniprot id: A0A1B1Y5Z6
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1790137:AXE80 RS08670
gene id: 1790137:AXE80_RS08670
uniprot id: A0A1B1Y6F0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1790137:AXE80 RS09315
gene id: 1790137:AXE80_RS09315
uniprot id: A0A1B1Y6U4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1790137:AXE80 RS09750
gene id: 1790137:AXE80_RS09750
uniprot id: A0A1B1Y719
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1790137:AXE80 RS13100
gene id: 1790137:AXE80_RS13100
uniprot id: A0A1B1Y8R5
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1790137:AXE80 RS13810
gene id: 1790137:AXE80_RS13810
uniprot id: A0A1B1Y943
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1790137:AXE80 RS06410
gene id: 1790137:AXE80_RS06410
uniprot id: A0A1B1Y570
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1790137:AXE80 RS10360
gene id: 1790137:AXE80_RS10360
uniprot id: A0A1B1Y7D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS03560
gene id: 1790137:AXE80_RS03560
uniprot id: A0A1B1Y3S0
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS13660
gene id: 1790137:AXE80_RS13660
uniprot id: A0A1B1Y914
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS05055
gene id: 1790137:AXE80_RS05055
uniprot id: A0A1B1Y4K7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS08265
gene id: 1790137:AXE80_RS08265
uniprot id: A0A1B1Y698
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1790137:AXE80 RS13180
gene id: 1790137:AXE80_RS13180
uniprot id: A0A1B1Y8X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1790137:AXE80 RS04315
gene id: 1790137:AXE80_RS04315
uniprot id: A0A1B1Y447
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1790137:AXE80 RS07620
gene id: 1790137:AXE80_RS07620
uniprot id: A0A1B1Y5W5
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1790137:AXE80 RS07355
gene id: 1790137:AXE80_RS07355
uniprot id: A0A1B1Y9K3
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS13220
gene id: 1790137:AXE80_RS13220
uniprot id: A0A1B1Y8V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1790137:AXE80 RS10085
gene id: 1790137:AXE80_RS10085
uniprot id: A0A1B1Y759
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1790137:AXE80 RS09400
gene id: 1790137:AXE80_RS09400
uniprot id: A0A1B1Y6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1790137:AXE80 RS02290
gene id: 1790137:AXE80_RS02290
uniprot id: A0A1B1Y347
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1790137:AXE80 RS00350
gene id: 1790137:AXE80_RS00350
uniprot id: A0A1B1Y240
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1790137:AXE80 RS10965
gene id: 1790137:AXE80_RS10965
uniprot id: A0A1B1Y7K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1790137:AXE80 RS00620
gene id: 1790137:AXE80_RS00620
uniprot id: A0A1B1Y286
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1790137:AXE80 RS02000
gene id: 1790137:AXE80_RS02000
uniprot id: A0A1B1Y2Y5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

1790137:AXE80 RS12455
gene id: 1790137:AXE80_RS12455
uniprot id: A0A1B1Y8D8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1790137:AXE80 RS02280
gene id: 1790137:AXE80_RS02280
uniprot id: A0A1B1Y359
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1790137:AXE80 RS03120
gene id: 1790137:AXE80_RS03120
uniprot id: A0A1B1Y3M5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1790137:AXE80 RS02100
gene id: 1790137:AXE80_RS02100
uniprot id: A0A1B1Y342
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1790137:AXE80 RS00690
gene id: 1790137:AXE80_RS00690
uniprot id: A0A1B1Y2C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1790137:AXE80 RS06525
gene id: 1790137:AXE80_RS06525
uniprot id: A0A1B1Y5A4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1790137:AXE80 RS13570
gene id: 1790137:AXE80_RS13570
uniprot id: A0A1B1Y911
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1790137:AXE80 RS05530
gene id: 1790137:AXE80_RS05530
uniprot id: A0A1B1Y4T9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS07950
gene id: 1790137:AXE80_RS07950
uniprot id: A0A1B1Y625
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS06620
gene id: 1790137:AXE80_RS06620
uniprot id: A0A1B1Y5E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1790137:AXE80 RS03005
gene id: 1790137:AXE80_RS03005
uniprot id: A0A1B1Y3G1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1790137:AXE80 RS09355
gene id: 1790137:AXE80_RS09355
uniprot id: A0A1B1Y6Q5
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1790137:AXE80 RS12770
gene id: 1790137:AXE80_RS12770
uniprot id: A0A1B1Y9T4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1790137:AXE80 RS09945
gene id: 1790137:AXE80_RS09945
uniprot id: A0A1B1Y749
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1790137:AXE80 RS00705
gene id: 1790137:AXE80_RS00705
uniprot id: A0A1B1Y2A3
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1790137:AXE80 RS02815
gene id: 1790137:AXE80_RS02815
uniprot id: A0A1B1Y3E7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1790137:AXE80 RS09225
gene id: 1790137:AXE80_RS09225
uniprot id: A0A1B1Y6P8
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS01385
gene id: 1790137:AXE80_RS01385
uniprot id: A0A1B1Y2R7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1790137:AXE80 RS11165
gene id: 1790137:AXE80_RS11165
uniprot id: A0A1B1Y7P4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1790137:AXE80 RS01030
gene id: 1790137:AXE80_RS01030
uniprot id: A0A1B1Y2I2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1790137:AXE80 RS09715
gene id: 1790137:AXE80_RS09715
uniprot id: A0A1B1Y6Z6
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1790137:AXE80 RS02395
gene id: 1790137:AXE80_RS02395
uniprot id: A0A1B1Y368
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1790137:AXE80 RS11185
gene id: 1790137:AXE80_RS11185
uniprot id: A0A1B1Y7U3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS12890
gene id: 1790137:AXE80_RS12890
uniprot id: A0A1B1Y8L9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1790137:AXE80 RS01875
gene id: 1790137:AXE80_RS01875
uniprot id: A0A1B1Y2Z8
names: Similarity
messages: Belongs to the CinA family.

1790137:AXE80 RS12500
gene id: 1790137:AXE80_RS12500
uniprot id: A0A1B1Y8D6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1790137:AXE80 RS09130
gene id: 1790137:AXE80_RS09130
uniprot id: A0A1B1Y6R1
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS08985
gene id: 1790137:AXE80_RS08985
uniprot id: A0A1B1Y9M5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1790137:AXE80 RS09015
gene id: 1790137:AXE80_RS09015
uniprot id: A0A1B1Y6K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1790137:AXE80 RS08845
gene id: 1790137:AXE80_RS08845
uniprot id: A0A1B1Y6H7
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS05925
gene id: 1790137:AXE80_RS05925
uniprot id: A0A1B1Y4Z8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1790137:AXE80 RS07855
gene id: 1790137:AXE80_RS07855
uniprot id: A0A1B1Y9Q6
names: Similarity
messages: Belongs to the UPF0045 family.

1790137:AXE80 RS01705
gene id: 1790137:AXE80_RS01705
uniprot id: A0A1B1Y2Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS00185
gene id: 1790137:AXE80_RS00185
uniprot id: A0A1B1Y210
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS04380
gene id: 1790137:AXE80_RS04380
uniprot id: A0A1B1Y448
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1790137:AXE80 RS08200
gene id: 1790137:AXE80_RS08200
uniprot id: A0A1B1Y685
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1790137:AXE80 RS13250
gene id: 1790137:AXE80_RS13250
uniprot id: A0A1B1Y8U4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1790137:AXE80 RS02640
gene id: 1790137:AXE80_RS02640
uniprot id: A0A1B1Y3B8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1790137:AXE80 RS09020
gene id: 1790137:AXE80_RS09020
uniprot id: A0A1B1Y6N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1790137:AXE80 RS09450
gene id: 1790137:AXE80_RS09450
uniprot id: A0A1B1Y6W7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1790137:AXE80 RS03900
gene id: 1790137:AXE80_RS03900
uniprot id: A0A1B1Y3V8
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1790137:AXE80 RS00885
gene id: 1790137:AXE80_RS00885
uniprot id: A0A1B1Y2D7
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS09065
gene id: 1790137:AXE80_RS09065
uniprot id: A0A1B1Y6M2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1790137:AXE80 RS13310
gene id: 1790137:AXE80_RS13310
uniprot id: A0A1B1Y8X9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1790137:AXE80 RS03645
gene id: 1790137:AXE80_RS03645
uniprot id: A0A1B1Y3T1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1790137:AXE80 RS04235
gene id: 1790137:AXE80_RS04235
uniprot id: A0A1B1Y434
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1790137:AXE80 RS11000
gene id: 1790137:AXE80_RS11000
uniprot id: A0A1B1Y7N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1790137:AXE80 RS04015
gene id: 1790137:AXE80_RS04015
uniprot id: A0A1B1Y3Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1790137:AXE80 RS02095
gene id: 1790137:AXE80_RS02095
uniprot id: A0A1B1Y329
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1790137:AXE80 RS06940
gene id: 1790137:AXE80_RS06940
uniprot id: A0A1B1Y5K6
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1790137:AXE80 RS02110
gene id: 1790137:AXE80_RS02110
uniprot id: A0A1B1Y312
names: Similarity
messages: Belongs to the ParB family.

1790137:AXE80 RS06150
gene id: 1790137:AXE80_RS06150
uniprot id: A0A1B1Y550
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS09050
gene id: 1790137:AXE80_RS09050
uniprot id: A0A1B1Y6K6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS01685
gene id: 1790137:AXE80_RS01685
uniprot id: A0A1B1Y2T4
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS00245
gene id: 1790137:AXE80_RS00245
uniprot id: A0A1B1Y220
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1790137:AXE80 RS13515
gene id: 1790137:AXE80_RS13515
uniprot id: A0A1B1Y919
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1790137:AXE80 RS13950
gene id: 1790137:AXE80_RS13950
uniprot id: A0A1B1Y996
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1790137:AXE80 RS05645
gene id: 1790137:AXE80_RS05645
uniprot id: A0A1B1Y4U2
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS10990
gene id: 1790137:AXE80_RS10990
uniprot id: A0A1B1Y7L7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1790137:AXE80 RS04925
gene id: 1790137:AXE80_RS04925
uniprot id: A0A1B1Y4J3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1790137:AXE80 RS07615
gene id: 1790137:AXE80_RS07615
uniprot id: A0A1B1Y9N6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1790137:AXE80 RS11010
gene id: 1790137:AXE80_RS11010
uniprot id: A0A1B1Y7Q5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1790137:AXE80 RS01200
gene id: 1790137:AXE80_RS01200
uniprot id: A0A1B1Y2L1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1790137:AXE80 RS00340
gene id: 1790137:AXE80_RS00340
uniprot id: A0A1B1Y239
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS09550
gene id: 1790137:AXE80_RS09550
uniprot id: A0A1B1Y6Y5
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1790137:AXE80 RS03450
gene id: 1790137:AXE80_RS03450
uniprot id: A0A1B1Y3S2
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1790137:AXE80 RS03870
gene id: 1790137:AXE80_RS03870
uniprot id: A0A1B1Y3X2
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1790137:AXE80 RS13550
gene id: 1790137:AXE80_RS13550
uniprot id: A0A1B1Y8Z3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1790137:AXE80 RS02865
gene id: 1790137:AXE80_RS02865
uniprot id: A0A1B1Y3F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1790137:AXE80 RS02205
gene id: 1790137:AXE80_RS02205
uniprot id: A0A1B1Y361
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS06380
gene id: 1790137:AXE80_RS06380
uniprot id: A0A1B1Y571
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1790137:AXE80 RS12505
gene id: 1790137:AXE80_RS12505
uniprot id: A0A1B1Y8F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1790137:AXE80 RS11330
gene id: 1790137:AXE80_RS11330
uniprot id: A0A1B1Y7S9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1790137:AXE80 RS11450
gene id: 1790137:AXE80_RS11450
uniprot id: A0A1B1Y7V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1790137:AXE80 RS00480
gene id: 1790137:AXE80_RS00480
uniprot id: A0A1B1Y289
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1790137:AXE80 RS12305
gene id: 1790137:AXE80_RS12305
uniprot id: A0A1B1Y8B1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS03090
gene id: 1790137:AXE80_RS03090
uniprot id: A0A1B1Y3J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1790137:AXE80 RS09075
gene id: 1790137:AXE80_RS09075
uniprot id: A0A1B1Y6P5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS03605
gene id: 1790137:AXE80_RS03605
uniprot id: A0A1B1Y3V4
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1790137:AXE80 RS11420
gene id: 1790137:AXE80_RS11420
uniprot id: A0A1B1Y7U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1790137:AXE80 RS00900
gene id: 1790137:AXE80_RS00900
uniprot id: A0A1B1Y2G1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS01780
gene id: 1790137:AXE80_RS01780
uniprot id: A0A1B1Y2V4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1790137:AXE80 RS13425
gene id: 1790137:AXE80_RS13425
uniprot id: A0A1B1Y8Z0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1790137:AXE80 RS14125
gene id: 1790137:AXE80_RS14125
uniprot id: A0A1B1Y9F8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS06185
gene id: 1790137:AXE80_RS06185
uniprot id: A0A1B1Y572
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1790137:AXE80 RS00755
gene id: 1790137:AXE80_RS00755
uniprot id: A0A1B1Y2D4
names: Similarity
messages: Belongs to the sigma-54 factor family.

1790137:AXE80 RS02715
gene id: 1790137:AXE80_RS02715
uniprot id: A0A1B1Y3C7
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS01575
gene id: 1790137:AXE80_RS01575
uniprot id: A0A1B1Y2R1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1790137:AXE80 RS02260
gene id: 1790137:AXE80_RS02260
uniprot id: A0A1B1Y321
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1790137:AXE80 RS03095
gene id: 1790137:AXE80_RS03095
uniprot id: A0A1B1Y3I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1790137:AXE80 RS13005
gene id: 1790137:AXE80_RS13005
uniprot id: A0A1B1Y8P9
names: Similarity
messages: Belongs to the Skp family.

1790137:AXE80 RS01350
gene id: 1790137:AXE80_RS01350
uniprot id: A0A1B1Y2P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1790137:AXE80 RS09125
gene id: 1790137:AXE80_RS09125
uniprot id: A0A1B1Y6Q6
names: Similarity
messages: Belongs to the sterol desaturase family.

1790137:AXE80 RS13635
gene id: 1790137:AXE80_RS13635
uniprot id: A0A1B1Y934
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1790137:AXE80 RS10970
gene id: 1790137:AXE80_RS10970
uniprot id: A0A1B1Y9S5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1790137:AXE80 RS07945
gene id: 1790137:AXE80_RS07945
uniprot id: A0A1B1Y634
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1790137:AXE80 RS00270
gene id: 1790137:AXE80_RS00270
uniprot id: A0A1B1Y227
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1790137:AXE80 RS10280
gene id: 1790137:AXE80_RS10280
uniprot id: A0A1B1Y791
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1790137:AXE80 RS12270
gene id: 1790137:AXE80_RS12270
uniprot id: A0A1B1Y8B6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1790137:AXE80 RS07515
gene id: 1790137:AXE80_RS07515
uniprot id: A0A1B1Y5R7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS02010
gene id: 1790137:AXE80_RS02010
uniprot id: A0A1B1Y9K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1790137:AXE80 RS08720
gene id: 1790137:AXE80_RS08720
uniprot id: A0A1B1Y6E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1790137:AXE80 RS01135
gene id: 1790137:AXE80_RS01135
uniprot id: A0A1B1Y2L2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1790137:AXE80 RS02525
gene id: 1790137:AXE80_RS02525
uniprot id: A0A1B1Y371
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS00190
gene id: 1790137:AXE80_RS00190
uniprot id: A0A1B1Y205
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1790137:AXE80 RS10020
gene id: 1790137:AXE80_RS10020
uniprot id: A0A1B1Y739
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

1790137:AXE80 RS11250
gene id: 1790137:AXE80_RS11250
uniprot id: A0A1B1Y7T8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1790137:AXE80 RS11795
gene id: 1790137:AXE80_RS11795
uniprot id: A0A1B1Y870
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1790137:AXE80 RS04280
gene id: 1790137:AXE80_RS04280
uniprot id: A0A1B1Y445
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1790137:AXE80 RS01665
gene id: 1790137:AXE80_RS01665
uniprot id: A0A1B1Y2U1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1790137:AXE80 RS11965
gene id: 1790137:AXE80_RS11965
uniprot id: A0A1B1Y849
names: Similarity
messages: Belongs to the peptidase S24 family.

1790137:AXE80 RS12665
gene id: 1790137:AXE80_RS12665
uniprot id: A0A1B1Y8H1
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1790137:AXE80 RS02620
gene id: 1790137:AXE80_RS02620
uniprot id: A0A1B1Y399
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

1790137:AXE80 RS08955
gene id: 1790137:AXE80_RS08955
uniprot id: A0A1B1Y6K2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1790137:AXE80 RS00670
gene id: 1790137:AXE80_RS00670
uniprot id: A0A1B1Y299
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS01840
gene id: 1790137:AXE80_RS01840
uniprot id: A0A1B1Y2W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1790137:AXE80 RS12625
gene id: 1790137:AXE80_RS12625
uniprot id: A0A1B1Y8H8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS02220
gene id: 1790137:AXE80_RS02220
uniprot id: A0A1B1Y319
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1790137:AXE80 RS05995
gene id: 1790137:AXE80_RS05995
uniprot id: A0A1B1Y504
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1790137:AXE80 RS05465
gene id: 1790137:AXE80_RS05465
uniprot id: A0A1B1Y4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1790137:AXE80 RS13030
gene id: 1790137:AXE80_RS13030
uniprot id: A0A1B1Y8V6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1790137:AXE80 RS02645
gene id: 1790137:AXE80_RS02645
uniprot id: A0A1B1Y3D3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1790137:AXE80 RS04130
gene id: 1790137:AXE80_RS04130
uniprot id: A0A1B1Y419
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS06830
gene id: 1790137:AXE80_RS06830
uniprot id: A0A1B1Y5I5
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1790137:AXE80 RS06440
gene id: 1790137:AXE80_RS06440
uniprot id: A0A1B1Y581
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1790137:AXE80 RS10195
gene id: 1790137:AXE80_RS10195
uniprot id: A0A1B1Y774
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1790137:AXE80 RS12860
gene id: 1790137:AXE80_RS12860
uniprot id: A0A1B1Y9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1790137:AXE80 RS03685
gene id: 1790137:AXE80_RS03685
uniprot id: A0A1B1Y3U1
names: Similarity
messages: Belongs to the P(II) protein family.

1790137:AXE80 RS05090
gene id: 1790137:AXE80_RS05090
uniprot id: A0A1B1Y4H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS04565
gene id: 1790137:AXE80_RS04565
uniprot id: A0A1B1Y4B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1790137:AXE80 RS00625
gene id: 1790137:AXE80_RS00625
uniprot id: A0A1B1Y290
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS10225
gene id: 1790137:AXE80_RS10225
uniprot id: A0A1B1Y781
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS12145
gene id: 1790137:AXE80_RS12145
uniprot id: A0A1B1Y879
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1790137:AXE80 RS11475
gene id: 1790137:AXE80_RS11475
uniprot id: A0A1B1Y7W0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1790137:AXE80 RS05415
gene id: 1790137:AXE80_RS05415
uniprot id: A0A1B1Y4T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1790137:AXE80 RS04195
gene id: 1790137:AXE80_RS04195
uniprot id: A0A1B1Y446
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1790137:AXE80 RS07105
gene id: 1790137:AXE80_RS07105
uniprot id: A0A1B1Y5L0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS08310
gene id: 1790137:AXE80_RS08310
uniprot id: A0A1B1Y6B2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS01845
gene id: 1790137:AXE80_RS01845
uniprot id: A0A1B1Y2W6
names: Similarity
messages: Belongs to the fabD family.

1790137:AXE80 RS04635
gene id: 1790137:AXE80_RS04635
uniprot id: A0A1B1Y4B1
names: Similarity
messages: Belongs to the Dps family.

1790137:AXE80 RS08005
gene id: 1790137:AXE80_RS08005
uniprot id: A0A1B1Y606
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS01540
gene id: 1790137:AXE80_RS01540
uniprot id: A0A1B1Y2U6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS11930
gene id: 1790137:AXE80_RS11930
uniprot id: A0A1B1Y831
names: Similarity
messages: Belongs to the peptidase C40 family.

1790137:AXE80 RS03835
gene id: 1790137:AXE80_RS03835
uniprot id: A0A1B1Y3X4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

1790137:AXE80 RS12395
gene id: 1790137:AXE80_RS12395
uniprot id: A0A1B1Y8C9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS01865
gene id: 1790137:AXE80_RS01865
uniprot id: A0A1B1Y2W4
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1790137:AXE80 RS12245
gene id: 1790137:AXE80_RS12245
uniprot id: A0A1B1Y8A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1790137:AXE80 RS01325
gene id: 1790137:AXE80_RS01325
uniprot id: A0A1B1Y2L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1790137:AXE80 RS09605
gene id: 1790137:AXE80_RS09605
uniprot id: A0A1B1Y6Z3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1790137:AXE80 RS00935
gene id: 1790137:AXE80_RS00935
uniprot id: A0A1B1Y2E7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1790137:AXE80 RS02565
gene id: 1790137:AXE80_RS02565
uniprot id: A0A1B1Y374
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1790137:AXE80 RS03715
gene id: 1790137:AXE80_RS03715
uniprot id: A0A1B1Y3U5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1790137:AXE80 RS09135
gene id: 1790137:AXE80_RS09135
uniprot id: A0A1B1Y6R0
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1790137:AXE80 RS13415
gene id: 1790137:AXE80_RS13415
uniprot id: A0A1B1Y8Z9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1790137:AXE80 RS02690
gene id: 1790137:AXE80_RS02690
uniprot id: A0A1B1Y3D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1790137:AXE80 RS07040
gene id: 1790137:AXE80_RS07040
uniprot id: A0A1B1Y5K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS00645
gene id: 1790137:AXE80_RS00645
uniprot id: A0A1B1Y2C1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS08925
gene id: 1790137:AXE80_RS08925
uniprot id: A0A1B1Y6J6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS08355
gene id: 1790137:AXE80_RS08355
uniprot id: A0A1B1Y696
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1790137:AXE80 RS09915
gene id: 1790137:AXE80_RS09915
uniprot id: A0A1B1Y711
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1790137:AXE80 RS11410
gene id: 1790137:AXE80_RS11410
uniprot id: A0A1B1Y7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1790137:AXE80 RS02350
gene id: 1790137:AXE80_RS02350
uniprot id: A0A1B1Y337
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1790137:AXE80 RS02650
gene id: 1790137:AXE80_RS02650
uniprot id: A0A1B1Y3D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1790137:AXE80 RS09660
gene id: 1790137:AXE80_RS09660
uniprot id: A0A1B1Y6Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1790137:AXE80 RS00160
gene id: 1790137:AXE80_RS00160
uniprot id: A0A1B1Y228
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1790137:AXE80 RS13070
gene id: 1790137:AXE80_RS13070
uniprot id: A0A1B1Y9W4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1790137:AXE80 RS06370
gene id: 1790137:AXE80_RS06370
uniprot id: A0A1B1Y593
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1790137:AXE80 RS05335
gene id: 1790137:AXE80_RS05335
uniprot id: A0A1B1Y4M4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1790137:AXE80 RS05345
gene id: 1790137:AXE80_RS05345
uniprot id: A0A1B1Y4Q9
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS08385
gene id: 1790137:AXE80_RS08385
uniprot id: A0A1B1Y699
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1790137:AXE80 RS04530
gene id: 1790137:AXE80_RS04530
uniprot id: A0A1B1Y477
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS01810
gene id: 1790137:AXE80_RS01810
uniprot id: A0A1B1Y2U9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1790137:AXE80 RS12170
gene id: 1790137:AXE80_RS12170
uniprot id: A0A1B1Y894
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

1790137:AXE80 RS11005
gene id: 1790137:AXE80_RS11005
uniprot id: A0A1B1Y7Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1790137:AXE80 RS13400
gene id: 1790137:AXE80_RS13400
uniprot id: A0A1B1Y9R3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1790137:AXE80 RS06345
gene id: 1790137:AXE80_RS06345
uniprot id: A0A1B1Y5A5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1790137:AXE80 RS09405
gene id: 1790137:AXE80_RS09405
uniprot id: A0A1B1Y6W0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1790137:AXE80 RS11500
gene id: 1790137:AXE80_RS11500
uniprot id: A0A1B1Y7W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1790137:AXE80 RS07100
gene id: 1790137:AXE80_RS07100
uniprot id: A0A1B1Y5N1
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS10620
gene id: 1790137:AXE80_RS10620
uniprot id: A0A1B1Y7I5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1790137:AXE80 RS12420
gene id: 1790137:AXE80_RS12420
uniprot id: A0A1B1Y8F0
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS12430
gene id: 1790137:AXE80_RS12430
uniprot id: A0A1B1Y8J2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1790137:AXE80 RS13375
gene id: 1790137:AXE80_RS13375
uniprot id: A0A1B1Y8W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS04350
gene id: 1790137:AXE80_RS04350
uniprot id: A0A1B1Y461
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1790137:AXE80 RS02825
gene id: 1790137:AXE80_RS02825
uniprot id: A0A1B1Y3E3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS07530
gene id: 1790137:AXE80_RS07530
uniprot id: A0A1B1Y5X1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1790137:AXE80 RS14025
gene id: 1790137:AXE80_RS14025
uniprot id: A0A1B1Y980
names: Similarity
messages: Belongs to the peptidase S8 family.

1790137:AXE80 RS04355
gene id: 1790137:AXE80_RS04355
uniprot id: A0A1B1Y456
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1790137:AXE80 RS09800
gene id: 1790137:AXE80_RS09800
uniprot id: A0A1B1Y729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1790137:AXE80 RS03440
gene id: 1790137:AXE80_RS03440
uniprot id: A0A1B1Y3N8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1790137:AXE80 RS00605
gene id: 1790137:AXE80_RS00605
uniprot id: A0A1B1Y283
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1790137:AXE80 RS00770
gene id: 1790137:AXE80_RS00770
uniprot id: A0A1B1Y2B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1790137:AXE80 RS03520
gene id: 1790137:AXE80_RS03520
uniprot id: A0A1B1Y3Q0
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS04375
gene id: 1790137:AXE80_RS04375
uniprot id: A0A1B1Y457
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1790137:AXE80 RS09245
gene id: 1790137:AXE80_RS09245
uniprot id: A0A1B1Y6Q4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1790137:AXE80 RS05295
gene id: 1790137:AXE80_RS05295
uniprot id: A0A1B1Y4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1790137:AXE80 RS03755
gene id: 1790137:AXE80_RS03755
uniprot id: A0A1B1Y3V2
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1790137:AXE80 RS13410
gene id: 1790137:AXE80_RS13410
uniprot id: A0A1B1Y8W8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1790137:AXE80 RS12265
gene id: 1790137:AXE80_RS12265
uniprot id: A0A1B1Y8B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1790137:AXE80 RS02210
gene id: 1790137:AXE80_RS02210
uniprot id: A0A1B1Y335
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS00945
gene id: 1790137:AXE80_RS00945
uniprot id: A0A1B1Y2I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS10585
gene id: 1790137:AXE80_RS10585
uniprot id: A0A1B1Y7F9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1790137:AXE80 RS05035
gene id: 1790137:AXE80_RS05035
uniprot id: A0A1B1Y4H9
names: Similarity
messages: Belongs to the DinB family.

1790137:AXE80 RS02275
gene id: 1790137:AXE80_RS02275
uniprot id: A0A1B1Y355
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1790137:AXE80 RS13335
gene id: 1790137:AXE80_RS13335
uniprot id: A0A1B1Y916
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS01145
gene id: 1790137:AXE80_RS01145
uniprot id: A0A1B1Y2I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1790137:AXE80 RS07590
gene id: 1790137:AXE80_RS07590
uniprot id: A0A1B1Y5V1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1790137:AXE80 RS04115
gene id: 1790137:AXE80_RS04115
uniprot id: A0A1B1Y405
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS01340
gene id: 1790137:AXE80_RS01340
uniprot id: A0A1B1Y2P5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1790137:AXE80 RS09620
gene id: 1790137:AXE80_RS09620
uniprot id: A0A1B1Y6X4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1790137:AXE80 RS09310
gene id: 1790137:AXE80_RS09310
uniprot id: A0A1B1Y6S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1790137:AXE80 RS00320
gene id: 1790137:AXE80_RS00320
uniprot id: A0A1B1Y236
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1790137:AXE80 RS07775
gene id: 1790137:AXE80_RS07775
uniprot id: A0A1B1Y617
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1790137:AXE80 RS12260
gene id: 1790137:AXE80_RS12260
uniprot id: A0A1B1Y8C8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1790137:AXE80 RS05990
gene id: 1790137:AXE80_RS05990
uniprot id: A0A1B1Y508
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS04320
gene id: 1790137:AXE80_RS04320
uniprot id: A0A1B1Y438
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1790137:AXE80 RS13740
gene id: 1790137:AXE80_RS13740
uniprot id: A0A1B1Y933
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1790137:AXE80 RS13555
gene id: 1790137:AXE80_RS13555
uniprot id: A0A1B1Y905
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1790137:AXE80 RS04760
gene id: 1790137:AXE80_RS04760
uniprot id: A0A1B1Y4G0
names: Similarity
messages: Belongs to the SUI1 family.

1790137:AXE80 RS06330
gene id: 1790137:AXE80_RS06330
uniprot id: A0A1B1Y562
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS13370
gene id: 1790137:AXE80_RS13370
uniprot id: A0A1B1Y8Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1790137:AXE80 RS06285
gene id: 1790137:AXE80_RS06285
uniprot id: A0A1B1Y551
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS00455
gene id: 1790137:AXE80_RS00455
uniprot id: A0A1B1Y9F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1790137:AXE80 RS10995
gene id: 1790137:AXE80_RS10995
uniprot id: A0A1B1Y7M9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1790137:AXE80 RS08130
gene id: 1790137:AXE80_RS08130
uniprot id: A0A1B1Y649
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS05365
gene id: 1790137:AXE80_RS05365
uniprot id: A0A1B1Y4S3
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS10680
gene id: 1790137:AXE80_RS10680
uniprot id: A0A1B1Y7G6
names: Similarity
messages: Belongs to the DEAD box helicase family.

1790137:AXE80 RS08675
gene id: 1790137:AXE80_RS08675
uniprot id: A0A1B1Y6I2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1790137:AXE80 RS01710
gene id: 1790137:AXE80_RS01710
uniprot id: A0A1B1Y2V8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1790137:AXE80 RS12105
gene id: 1790137:AXE80_RS12105
uniprot id: A0A1B1Y864
names: Similarity
messages: Belongs to the SufE family.

1790137:AXE80 RS09085
gene id: 1790137:AXE80_RS09085
uniprot id: A0A1B1Y6Q0
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS09880
gene id: 1790137:AXE80_RS09880
uniprot id: A0A1B1Y720
names: Similarity
messages: Belongs to the RecJ family.

1790137:AXE80 RS00910
gene id: 1790137:AXE80_RS00910
uniprot id: A0A1B1Y2G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS09870
gene id: 1790137:AXE80_RS09870
uniprot id: A0A1B1Y725
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1790137:AXE80 RS01045
gene id: 1790137:AXE80_RS01045
uniprot id: A0A1B1Y2G8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1790137:AXE80 RS13255
gene id: 1790137:AXE80_RS13255
uniprot id: A0A1B1Y8T8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS06835
gene id: 1790137:AXE80_RS06835
uniprot id: A0A1B1Y5I0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS08525
gene id: 1790137:AXE80_RS08525
uniprot id: A0A1B1Y6B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1790137:AXE80 RS04075
gene id: 1790137:AXE80_RS04075
uniprot id: A0A1B1Y415
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1790137:AXE80 RS07760
gene id: 1790137:AXE80_RS07760
uniprot id: A0A1B1Y5Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS07880
gene id: 1790137:AXE80_RS07880
uniprot id: A0A1B1Y620
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1790137:AXE80 RS10190
gene id: 1790137:AXE80_RS10190
uniprot id: A0A1B1Y9T3
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS12315
gene id: 1790137:AXE80_RS12315
uniprot id: A0A1B1Y8C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1790137:AXE80 RS12230
gene id: 1790137:AXE80_RS12230
uniprot id: A0A1B1Y8E9
names: Similarity
messages: Belongs to the peptidase C40 family.

1790137:AXE80 RS02890
gene id: 1790137:AXE80_RS02890
uniprot id: A0A1B1Y3E8
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS09055
gene id: 1790137:AXE80_RS09055
uniprot id: A0A1B1Y6M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1790137:AXE80 RS08000
gene id: 1790137:AXE80_RS08000
uniprot id: A0A1B1Y635
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS06265
gene id: 1790137:AXE80_RS06265
uniprot id: A0A1B1Y554
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1790137:AXE80 RS06950
gene id: 1790137:AXE80_RS06950
uniprot id: A0A1B1Y9M6
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1790137:AXE80 RS00700
gene id: 1790137:AXE80_RS00700
uniprot id: A0A1B1Y2C5
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS08595
gene id: 1790137:AXE80_RS08595
uniprot id: A0A1B1Y6G0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1790137:AXE80 RS13840
gene id: 1790137:AXE80_RS13840
uniprot id: A0A1B1Y979
names: Similarity
messages: Belongs to the ComB family.

1790137:AXE80 RS06120
gene id: 1790137:AXE80_RS06120
uniprot id: A0A1B1Y559
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1790137:AXE80 RS02860
gene id: 1790137:AXE80_RS02860
uniprot id: A0A1B1Y3F6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1790137:AXE80 RS07575
gene id: 1790137:AXE80_RS07575
uniprot id: A0A1B1Y5T1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1790137:AXE80 RS04275
gene id: 1790137:AXE80_RS04275
uniprot id: A0A1B1Y9L9
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS06840
gene id: 1790137:AXE80_RS06840
uniprot id: A0A1B1Y5F2
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1790137:AXE80 RS11655
gene id: 1790137:AXE80_RS11655
uniprot id: A0A1B1Y802
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1790137:AXE80 RS09190
gene id: 1790137:AXE80_RS09190
uniprot id: A0A1B1Y6S1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1790137:AXE80 RS14055
gene id: 1790137:AXE80_RS14055
uniprot id: A0A1B1Y9U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1790137:AXE80 RS11470
gene id: 1790137:AXE80_RS11470
uniprot id: A0A1B1Y7Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1790137:AXE80 RS06080
gene id: 1790137:AXE80_RS06080
uniprot id: A0A1B1Y537
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS09665
gene id: 1790137:AXE80_RS09665
uniprot id: A0A1B1Y708
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1790137:AXE80 RS05715
gene id: 1790137:AXE80_RS05715
uniprot id: A0A1B1Y4V3
names: Similarity
messages: Belongs to the AHA1 family.

1790137:AXE80 RS12710
gene id: 1790137:AXE80_RS12710
uniprot id: A0A1B1Y8H9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1790137:AXE80 RS13145
gene id: 1790137:AXE80_RS13145
uniprot id: A0A1B1Y8R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1790137:AXE80 RS04400
gene id: 1790137:AXE80_RS04400
uniprot id: A0A1B1Y487
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1790137:AXE80 RS00890
gene id: 1790137:AXE80_RS00890
uniprot id: A0A1B1Y2D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1790137:AXE80 RS07925
gene id: 1790137:AXE80_RS07925
uniprot id: A0A1B1Y5Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1790137:AXE80 RS04225
gene id: 1790137:AXE80_RS04225
uniprot id: A0A1B1Y440
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1790137:AXE80 RS05025
gene id: 1790137:AXE80_RS05025
uniprot id: A0A1B1Y4K1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1790137:AXE80 RS00325
gene id: 1790137:AXE80_RS00325
uniprot id: A0A1B1Y237
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1790137:AXE80 RS11260
gene id: 1790137:AXE80_RS11260
uniprot id: A0A1B1Y7V4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1790137:AXE80 RS09415
gene id: 1790137:AXE80_RS09415
uniprot id: A0A1B1Y6R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS09525
gene id: 1790137:AXE80_RS09525
uniprot id: A0A1B1Y9N9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1790137:AXE80 RS10710
gene id: 1790137:AXE80_RS10710
uniprot id: A0A1B1Y7F3
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS09095
gene id: 1790137:AXE80_RS09095
uniprot id: A0A1B1Y6K7
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS01120
gene id: 1790137:AXE80_RS01120
uniprot id: A0A1B1Y2H4
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS13755
gene id: 1790137:AXE80_RS13755
uniprot id: A0A1B1Y932
names: Similarity
messages: Belongs to the UxaA family.

1790137:AXE80 RS02125
gene id: 1790137:AXE80_RS02125
uniprot id: A0A1B1Y302
names: Similarity
messages: Belongs to the nitroreductase family.

1790137:AXE80 RS07895
gene id: 1790137:AXE80_RS07895
uniprot id: A0A1B1Y615
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1790137:AXE80 RS12960
gene id: 1790137:AXE80_RS12960
uniprot id: A0A1B1Y8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

1790137:AXE80 RS03320
gene id: 1790137:AXE80_RS03320
uniprot id: A0A1B1Y3N1
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS01765
gene id: 1790137:AXE80_RS01765
uniprot id: A0A1B1Y2W8
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS00150
gene id: 1790137:AXE80_RS00150
uniprot id: A0A1B1Y222
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS08975
gene id: 1790137:AXE80_RS08975
uniprot id: A0A1B1Y6M9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1790137:AXE80 RS03085
gene id: 1790137:AXE80_RS03085
uniprot id: A0A1B1Y3H2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1790137:AXE80 RS12025
gene id: 1790137:AXE80_RS12025
uniprot id: A0A1B1Y867
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1790137:AXE80 RS04345
gene id: 1790137:AXE80_RS04345
uniprot id: A0A1B1Y474
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1790137:AXE80 RS01050
gene id: 1790137:AXE80_RS01050
uniprot id: A0A1B1Y9E2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1790137:AXE80 RS02520
gene id: 1790137:AXE80_RS02520
uniprot id: A0A1B1Y369
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1790137:AXE80 RS11485
gene id: 1790137:AXE80_RS11485
uniprot id: A0A1B1Y7V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1790137:AXE80 RS01595
gene id: 1790137:AXE80_RS01595
uniprot id: A0A1B1Y2V6
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS13675
gene id: 1790137:AXE80_RS13675
uniprot id: A0A1B1Y949
names: Similarity
messages: Belongs to the UPF0102 family.

1790137:AXE80 RS04255
gene id: 1790137:AXE80_RS04255
uniprot id: A0A1B1Y458
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1790137:AXE80 RS06780
gene id: 1790137:AXE80_RS06780
uniprot id: A0A1B1Y5H5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1790137:AXE80 RS12895
gene id: 1790137:AXE80_RS12895
uniprot id: A0A1B1Y8M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1790137:AXE80 RS10130
gene id: 1790137:AXE80_RS10130
uniprot id: A0A1B1Y790
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1790137:AXE80 RS04995
gene id: 1790137:AXE80_RS04995
uniprot id: A0A1B1Y4J6
names: Similarity
messages: Belongs to the peptidase S51 family.

1790137:AXE80 RS13645
gene id: 1790137:AXE80_RS13645
uniprot id: A0A1B1Y963
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1790137:AXE80 RS01880
gene id: 1790137:AXE80_RS01880
uniprot id: A0A1B1Y313
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1790137:AXE80 RS11275
gene id: 1790137:AXE80_RS11275
uniprot id: A0A1B1Y7R8
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

1790137:AXE80 RS07425
gene id: 1790137:AXE80_RS07425
uniprot id: A0A1B1Y5S5
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1790137:AXE80 RS12365
gene id: 1790137:AXE80_RS12365
uniprot id: A0A1B1Y8D3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1790137:AXE80 RS08990
gene id: 1790137:AXE80_RS08990
uniprot id: A0A1B1Y6I8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1790137:AXE80 RS02685
gene id: 1790137:AXE80_RS02685
uniprot id: A0A1B1Y3A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1790137:AXE80 RS11460
gene id: 1790137:AXE80_RS11460
uniprot id: A0A1B1Y7X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1790137:AXE80 RS03695
gene id: 1790137:AXE80_RS03695
uniprot id: A0A1B1Y3U2
names: Similarity
messages: Belongs to the P(II) protein family.

1790137:AXE80 RS04430
gene id: 1790137:AXE80_RS04430
uniprot id: A0A1B1Y463
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1790137:AXE80 RS14080
gene id: 1790137:AXE80_RS14080
uniprot id: A0A1B1Y990
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1790137:AXE80 RS11345
gene id: 1790137:AXE80_RS11345
uniprot id: A0A1B1Y7U9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1790137:AXE80 RS13395
gene id: 1790137:AXE80_RS13395
uniprot id: A0A1B1Y8W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1790137:AXE80 RS11615
gene id: 1790137:AXE80_RS11615
uniprot id: A0A1B1Y813
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1790137:AXE80 RS05485
gene id: 1790137:AXE80_RS05485
uniprot id: A0A1B1Y4Q0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1790137:AXE80 RS06785
gene id: 1790137:AXE80_RS06785
uniprot id: A0A1B1Y5G9
names: Similarity
messages: Belongs to the universal stress protein A family.

1790137:AXE80 RS03675
gene id: 1790137:AXE80_RS03675
uniprot id: A0A1B1Y3S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS13875
gene id: 1790137:AXE80_RS13875
uniprot id: A0A1B1Y950
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS11525
gene id: 1790137:AXE80_RS11525
uniprot id: A0A1B1Y7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1790137:AXE80 RS06570
gene id: 1790137:AXE80_RS06570
uniprot id: A0A1B1Y5D2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1790137:AXE80 RS08790
gene id: 1790137:AXE80_RS08790
uniprot id: A0A1B1Y6H3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS12185
gene id: 1790137:AXE80_RS12185
uniprot id: A0A1B1Y8E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1790137:AXE80 RS04910
gene id: 1790137:AXE80_RS04910
uniprot id: A0A1B1Y4F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS00855
gene id: 1790137:AXE80_RS00855
uniprot id: A0A1B1Y2G2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS03935
gene id: 1790137:AXE80_RS03935
uniprot id: A0A1B1Y9J9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1790137:AXE80 RS01270
gene id: 1790137:AXE80_RS01270
uniprot id: A0A1B1Y2K1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1790137:AXE80 RS11875
gene id: 1790137:AXE80_RS11875
uniprot id: A0A1B1Y835
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1790137:AXE80 RS04120
gene id: 1790137:AXE80_RS04120
uniprot id: A0A1B1Y442
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1790137:AXE80 RS12880
gene id: 1790137:AXE80_RS12880
uniprot id: A0A1B1Y8K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1790137:AXE80 RS11220
gene id: 1790137:AXE80_RS11220
uniprot id: A0A1B1Y7Q4
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS02800
gene id: 1790137:AXE80_RS02800
uniprot id: A0A1B1Y3G3
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS13770
gene id: 1790137:AXE80_RS13770
uniprot id: A0A1B1Y931
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1790137:AXE80 RS13545
gene id: 1790137:AXE80_RS13545
uniprot id: A0A1B1Y8Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1790137:AXE80 RS10250
gene id: 1790137:AXE80_RS10250
uniprot id: A0A1B1Y783
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1790137:AXE80 RS01320
gene id: 1790137:AXE80_RS01320
uniprot id: A0A1B1Y2L0
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1790137:AXE80 RS09555
gene id: 1790137:AXE80_RS09555
uniprot id: A0A1B1Y6Y3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1790137:AXE80 RS01565
gene id: 1790137:AXE80_RS01565
uniprot id: A0A1B1Y2R9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1790137:AXE80 RS04045
gene id: 1790137:AXE80_RS04045
uniprot id: A0A1B1Y429
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1790137:AXE80 RS13300
gene id: 1790137:AXE80_RS13300
uniprot id: A0A1B1Y8V4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1790137:AXE80 RS01700
gene id: 1790137:AXE80_RS01700
uniprot id: A0A1B1Y2W1
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1790137:AXE80 RS11195
gene id: 1790137:AXE80_RS11195
uniprot id: A0A1B1Y7S1
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS04135
gene id: 1790137:AXE80_RS04135
uniprot id: A0A1B1Y427
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS02765
gene id: 1790137:AXE80_RS02765
uniprot id: A0A1B1Y3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1790137:AXE80 RS11040
gene id: 1790137:AXE80_RS11040
uniprot id: A0A1B1Y7M7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1790137:AXE80 RS09925
gene id: 1790137:AXE80_RS09925
uniprot id: A0A1B1Y733
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1790137:AXE80 RS02490
gene id: 1790137:AXE80_RS02490
uniprot id: A0A1B1Y3B4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

1790137:AXE80 RS10480
gene id: 1790137:AXE80_RS10480
uniprot id: A0A1B1Y7F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1790137:AXE80 RS05475
gene id: 1790137:AXE80_RS05475
uniprot id: A0A1B1Y4T6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1790137:AXE80 RS06955
gene id: 1790137:AXE80_RS06955
uniprot id: A0A1B1Y5J7
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1790137:AXE80 RS12945
gene id: 1790137:AXE80_RS12945
uniprot id: A0A1B1Y8N3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1790137:AXE80 RS12040
gene id: 1790137:AXE80_RS12040
uniprot id: A0A1B1Y861
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1790137:AXE80 RS11900
gene id: 1790137:AXE80_RS11900
uniprot id: A0A1B1Y888
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1790137:AXE80 RS00955
gene id: 1790137:AXE80_RS00955
uniprot id: A0A1B1Y2H9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1790137:AXE80 RS03410
gene id: 1790137:AXE80_RS03410
uniprot id: A0A1B1Y3P0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1790137:AXE80 RS06450
gene id: 1790137:AXE80_RS06450
uniprot id: A0A1B1Y5B9
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1790137:AXE80 RS03130
gene id: 1790137:AXE80_RS03130
uniprot id: A0A1B1Y3K9
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1790137:AXE80 RS01305
gene id: 1790137:AXE80_RS01305
uniprot id: A0A1B1Y2L9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1790137:AXE80 RS12150
gene id: 1790137:AXE80_RS12150
uniprot id: A0A1B1Y865
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS11660
gene id: 1790137:AXE80_RS11660
uniprot id: A0A1B1Y806
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1790137:AXE80 RS02810
gene id: 1790137:AXE80_RS02810
uniprot id: A0A1B1Y3E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1790137:AXE80 RS04220
gene id: 1790137:AXE80_RS04220
uniprot id: A0A1B1Y455
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1790137:AXE80 RS08260
gene id: 1790137:AXE80_RS08260
uniprot id: A0A1B1Y6A2
names: Similarity
messages: Belongs to the thioredoxin family.

1790137:AXE80 RS03850
gene id: 1790137:AXE80_RS03850
uniprot id: A0A1B1Y3V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1790137:AXE80 RS13505
gene id: 1790137:AXE80_RS13505
uniprot id: A0A1B1Y8Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1790137:AXE80 RS14185
gene id: 1790137:AXE80_RS14185
uniprot id: A0A1B1Y9B1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1790137:AXE80 RS08150
gene id: 1790137:AXE80_RS08150
uniprot id: A0A1B1Y676
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1790137:AXE80 RS04640
gene id: 1790137:AXE80_RS04640
uniprot id: A0A1B1Y4D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1790137:AXE80 RS11225
gene id: 1790137:AXE80_RS11225
uniprot id: A0A1B1Y7R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS00360
gene id: 1790137:AXE80_RS00360
uniprot id: A0A1B1Y266
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS13355
gene id: 1790137:AXE80_RS13355
uniprot id: A0A1B1Y8V8
names: Similarity
messages: Belongs to the GARS family.

1790137:AXE80 RS12165
gene id: 1790137:AXE80_RS12165
uniprot id: A0A1B1Y892
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1790137:AXE80 RS12390
gene id: 1790137:AXE80_RS12390
uniprot id: A0A1B1Y8C4
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS01655
gene id: 1790137:AXE80_RS01655
uniprot id: A0A1B1Y2X4
names: Similarity
messages: Belongs to the aldose epimerase family.

1790137:AXE80 RS06555
gene id: 1790137:AXE80_RS06555
uniprot id: A0A1B1Y5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1790137:AXE80 RS13535
gene id: 1790137:AXE80_RS13535
uniprot id: A0A1B1Y940
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1790137:AXE80 RS13910
gene id: 1790137:AXE80_RS13910
uniprot id: A0A1B1Y9B0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1790137:AXE80 RS01235
gene id: 1790137:AXE80_RS01235
uniprot id: A0A1B1Y2N9
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1790137:AXE80 RS10345
gene id: 1790137:AXE80_RS10345
uniprot id: A0A1B1Y9P1
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS04920
gene id: 1790137:AXE80_RS04920
uniprot id: A0A1B1Y4I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1790137:AXE80 RS10435
gene id: 1790137:AXE80_RS10435
uniprot id: A0A1B1Y797
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS00915
gene id: 1790137:AXE80_RS00915
uniprot id: A0A1B1Y2F0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1790137:AXE80 RS11570
gene id: 1790137:AXE80_RS11570
uniprot id: A0A1B1Y822
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1790137:AXE80 RS12990
gene id: 1790137:AXE80_RS12990
uniprot id: A0A1B1Y8P5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1790137:AXE80 RS07665
gene id: 1790137:AXE80_RS07665
uniprot id: A0A1B1Y5Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1790137:AXE80 RS03995
gene id: 1790137:AXE80_RS03995
uniprot id: A0A1B1Y412
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS02840
gene id: 1790137:AXE80_RS02840
uniprot id: A0A1B1Y3C9
names: Similarity
messages: Belongs to the SCO1/2 family.

1790137:AXE80 RS09340
gene id: 1790137:AXE80_RS09340
uniprot id: A0A1B1Y9Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1790137:AXE80 RS03860
gene id: 1790137:AXE80_RS03860
uniprot id: A0A1B1Y3X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1790137:AXE80 RS02630
gene id: 1790137:AXE80_RS02630
uniprot id: A0A1B1Y389
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1790137:AXE80 RS09305
gene id: 1790137:AXE80_RS09305
uniprot id: A0A1B1Y6Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1790137:AXE80 RS11065
gene id: 1790137:AXE80_RS11065
uniprot id: A0A1B1Y7M4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1790137:AXE80 RS03325
gene id: 1790137:AXE80_RS03325
uniprot id: A0A1B1Y3N0
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS00980
gene id: 1790137:AXE80_RS00980
uniprot id: A0A1B1Y2F7
names: Similarity
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.

1790137:AXE80 RS11940
gene id: 1790137:AXE80_RS11940
uniprot id: A0A1B1Y836
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1790137:AXE80 RS12980
gene id: 1790137:AXE80_RS12980
uniprot id: A0A1B1Y8M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS11925
gene id: 1790137:AXE80_RS11925
uniprot id: A0A1B1Y838
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1790137:AXE80 RS12075
gene id: 1790137:AXE80_RS12075
uniprot id: A0A1B1Y875
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1790137:AXE80 RS13430
gene id: 1790137:AXE80_RS13430
uniprot id: A0A1B1Y8X5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1790137:AXE80 RS04335
gene id: 1790137:AXE80_RS04335
uniprot id: A0A1B1Y479
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1790137:AXE80 RS05225
gene id: 1790137:AXE80_RS05225
uniprot id: A0A1B1Y4M7
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS01195
gene id: 1790137:AXE80_RS01195
uniprot id: A0A1B1Y2M2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1790137:AXE80 RS01345
gene id: 1790137:AXE80_RS01345
uniprot id: A0A1B1Y2Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1790137:AXE80 RS13290
gene id: 1790137:AXE80_RS13290
uniprot id: A0A1B1Y8U1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1790137:AXE80 RS01400
gene id: 1790137:AXE80_RS01400
uniprot id: A0A1B1Y2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1790137:AXE80 RS09165
gene id: 1790137:AXE80_RS09165
uniprot id: A0A1B1Y6R9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1790137:AXE80 RS09540
gene id: 1790137:AXE80_RS09540
uniprot id: A0A1B1Y6W5
names: Similarity
messages: Belongs to the RutC family.

1790137:AXE80 RS02440
gene id: 1790137:AXE80_RS02440
uniprot id: A0A1B1Y379
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1790137:AXE80 RS09060
gene id: 1790137:AXE80_RS09060
uniprot id: A0A1B1Y6P9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1790137:AXE80 RS06595
gene id: 1790137:AXE80_RS06595
uniprot id: A0A1B1Y5D4
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS07395
gene id: 1790137:AXE80_RS07395
uniprot id: A0A1B1Y5U6
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1790137:AXE80 RS08040
gene id: 1790137:AXE80_RS08040
uniprot id: A0A1B1Y652
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS07600
gene id: 1790137:AXE80_RS07600
uniprot id: A0A1B1Y5X2
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1790137:AXE80 RS06795
gene id: 1790137:AXE80_RS06795
uniprot id: A0A1B1Y5E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1790137:AXE80 RS08820
gene id: 1790137:AXE80_RS08820
uniprot id: A0A1B1Y6F7
names: Similarity
messages: Belongs to the aspartokinase family.

1790137:AXE80 RS00615
gene id: 1790137:AXE80_RS00615
uniprot id: A0A1B1Y288
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1790137:AXE80 RS13710
gene id: 1790137:AXE80_RS13710
uniprot id: A0A1B1Y920
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1790137:AXE80 RS06815
gene id: 1790137:AXE80_RS06815
uniprot id: A0A1B1Y5F1
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS13360
gene id: 1790137:AXE80_RS13360
uniprot id: A0A1B1Y8Y9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1790137:AXE80 RS09500
gene id: 1790137:AXE80_RS09500
uniprot id: A0A1B1Y6X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1790137:AXE80 RS01885
gene id: 1790137:AXE80_RS01885
uniprot id: A0A1B1Y2Y1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1790137:AXE80 RS05360
gene id: 1790137:AXE80_RS05360
uniprot id: A0A1B1Y4N2
names: Similarity
messages: Belongs to the FemABX family.

1790137:AXE80 RS12450
gene id: 1790137:AXE80_RS12450
uniprot id: A0A1B1Y8C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1790137:AXE80 RS01635
gene id: 1790137:AXE80_RS01635
uniprot id: A0A1B1Y2S6
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS12840
gene id: 1790137:AXE80_RS12840
uniprot id: A0A1B1Y8P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1790137:AXE80 RS11150
gene id: 1790137:AXE80_RS11150
uniprot id: A0A1B1Y7R9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1790137:AXE80 RS09360
gene id: 1790137:AXE80_RS09360
uniprot id: A0A1B1Y6R7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1790137:AXE80 RS06975
gene id: 1790137:AXE80_RS06975
uniprot id: A0A1B1Y5K9
names: Similarity
messages: Belongs to the UxaA family.

1790137:AXE80 RS02485
gene id: 1790137:AXE80_RS02485
uniprot id: A0A1B1Y3A5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1790137:AXE80 RS11160
gene id: 1790137:AXE80_RS11160
uniprot id: A0A1B1Y7T5
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1790137:AXE80 RS10355
gene id: 1790137:AXE80_RS10355
uniprot id: A0A1B1Y7D2
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS09290
gene id: 1790137:AXE80_RS09290
uniprot id: A0A1B1Y6T9
names: Subunit
messages: Homodimer.

1790137:AXE80 RS05130
gene id: 1790137:AXE80_RS05130
uniprot id: A0A1B1Y4J1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1790137:AXE80 RS01770
gene id: 1790137:AXE80_RS01770
uniprot id: A0A1B1Y2W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

1790137:AXE80 RS08710
gene id: 1790137:AXE80_RS08710
uniprot id: A0A1B1Y6F6
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS00660
gene id: 1790137:AXE80_RS00660
uniprot id: A0A1B1Y297
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1790137:AXE80 RS06310
gene id: 1790137:AXE80_RS06310
uniprot id: A0A1B1Y548
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1790137:AXE80 RS01950
gene id: 1790137:AXE80_RS01950
uniprot id: A0A1B1Y2X8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1790137:AXE80 RS00560
gene id: 1790137:AXE80_RS00560
uniprot id: A0A1B1Y278
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1790137:AXE80 RS13865
gene id: 1790137:AXE80_RS13865
uniprot id: A0A1B1Y9B3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1790137:AXE80 RS06350
gene id: 1790137:AXE80_RS06350
uniprot id: A0A1B1Y5A1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS02605
gene id: 1790137:AXE80_RS02605
uniprot id: A0A1B1Y3A6
names: Similarity
messages: Belongs to the ArsC family.

1790137:AXE80 RS06355
gene id: 1790137:AXE80_RS06355
uniprot id: A0A1B1Y587
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS10120
gene id: 1790137:AXE80_RS10120
uniprot id: A0A1B1Y786
names: Similarity
messages: Belongs to the peptidase M16 family.

1790137:AXE80 RS00250
gene id: 1790137:AXE80_RS00250
uniprot id: A0A1B1Y251
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS13575
gene id: 1790137:AXE80_RS13575
uniprot id: A0A1B1Y925
names: Similarity
messages: Belongs to the peptidase S41A family.

1790137:AXE80 RS11425
gene id: 1790137:AXE80_RS11425
uniprot id: A0A1B1Y7U2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1790137:AXE80 RS06200
gene id: 1790137:AXE80_RS06200
uniprot id: A0A1B1Y544
names: Cofactor
names: PTM
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.

1790137:AXE80 RS12475
gene id: 1790137:AXE80_RS12475
uniprot id: A0A1B1Y8E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1790137:AXE80 RS06810
gene id: 1790137:AXE80_RS06810
uniprot id: A0A1B1Y5F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS08280
gene id: 1790137:AXE80_RS08280
uniprot id: A0A1B1Y667
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1790137:AXE80 RS05195
gene id: 1790137:AXE80_RS05195
uniprot id: A0A1B1Y4K6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1790137:AXE80 RS13295
gene id: 1790137:AXE80_RS13295
uniprot id: A0A1B1Y8U3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1790137:AXE80 RS02295
gene id: 1790137:AXE80_RS02295
uniprot id: A0A1B1Y344
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1790137:AXE80 RS12155
gene id: 1790137:AXE80_RS12155
uniprot id: A0A1B1Y878
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1790137:AXE80 RS05580
gene id: 1790137:AXE80_RS05580
uniprot id: A0A1B1Y4U8
names: Subcellular Location Annotation
messages: Cell inner membrane

1790137:AXE80 RS03980
gene id: 1790137:AXE80_RS03980
uniprot id: A0A1B1Y3Y9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1790137:AXE80 RS13380
gene id: 1790137:AXE80_RS13380
uniprot id: A0A1B1Y913
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1790137:AXE80 RS02145
gene id: 1790137:AXE80_RS02145
uniprot id: A0A1B1Y334
names: Similarity
messages: Belongs to the LOG family.

1790137:AXE80 RS12020
gene id: 1790137:AXE80_RS12020
uniprot id: A0A1B1Y863
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1790137:AXE80 RS05045
gene id: 1790137:AXE80_RS05045
uniprot id: A0A1B1Y4L1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1790137:AXE80 RS13965
gene id: 1790137:AXE80_RS13965
uniprot id: A0A1B1Y9D1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1790137:AXE80 RS13445
gene id: 1790137:AXE80_RS13445
uniprot id: A0A1B1Y8X0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1790137:AXE80 RS00080
gene id: 1790137:AXE80_RS00080
uniprot id: A0A1B1Y1Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1790137:AXE80 RS07505
gene id: 1790137:AXE80_RS07505
uniprot id: A0A1B1Y5V6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1790137:AXE80 RS00365
gene id: 1790137:AXE80_RS00365
uniprot id: A0A1B1Y269
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1790137:AXE80 RS07500
gene id: 1790137:AXE80_RS07500
uniprot id: A0A1B1Y5W7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1790137:AXE80 RS00640
gene id: 1790137:AXE80_RS00640
uniprot id: A0A1B1Y9J1
names: Similarity
messages: Belongs to the ribF family.

1790137:AXE80 RS04915
gene id: 1790137:AXE80_RS04915
uniprot id: A0A1B1Y4E9
names: Similarity
messages: Belongs to the threonine synthase family.

1790137:AXE80 RS08530
gene id: 1790137:AXE80_RS08530
uniprot id: A0A1B1Y6E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1790137:AXE80 RS05720
gene id: 1790137:AXE80_RS05720
uniprot id: A0A1B1Y4V4
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS07835
gene id: 1790137:AXE80_RS07835
uniprot id: A0A1B1Y605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS11835
gene id: 1790137:AXE80_RS11835
uniprot id: A0A1B1Y842
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1790137:AXE80 RS13775
gene id: 1790137:AXE80_RS13775
uniprot id: A0A1B1Y969
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS07850
gene id: 1790137:AXE80_RS07850
uniprot id: A0A1B1Y600
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1790137:AXE80 RS11780
gene id: 1790137:AXE80_RS11780
uniprot id: A0A1B1Y9R0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1790137:AXE80 RS08610
gene id: 1790137:AXE80_RS08610
uniprot id: A0A1B1Y6B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1790137:AXE80 RS00830
gene id: 1790137:AXE80_RS00830
uniprot id: A0A1B1Y2C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1790137:AXE80 RS12600
gene id: 1790137:AXE80_RS12600
uniprot id: A0A1B1Y8G6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1790137:AXE80 RS04770
gene id: 1790137:AXE80_RS04770
uniprot id: A0A1B1Y4F7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1790137:AXE80 RS13080
gene id: 1790137:AXE80_RS13080
uniprot id: A0A1B1Y8V5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1790137:AXE80 RS10960
gene id: 1790137:AXE80_RS10960
uniprot id: A0A1B1Y7K1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1790137:AXE80 RS10145
gene id: 1790137:AXE80_RS10145
uniprot id: A0A1B1Y752
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS12720
gene id: 1790137:AXE80_RS12720
uniprot id: A0A1B1Y8I5
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS00840
gene id: 1790137:AXE80_RS00840
uniprot id: A0A1B1Y2C8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1790137:AXE80 RS00310
gene id: 1790137:AXE80_RS00310
uniprot id: A0A1B1Y260
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1790137:AXE80 RS12440
gene id: 1790137:AXE80_RS12440
uniprot id: A0A1B1Y8D5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1790137:AXE80 RS04395
gene id: 1790137:AXE80_RS04395
uniprot id: A0A1B1Y486
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1790137:AXE80 RS06320
gene id: 1790137:AXE80_RS06320
uniprot id: A0A1B1Y583
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1790137:AXE80 RS13155
gene id: 1790137:AXE80_RS13155
uniprot id: A0A1B1Y8R8
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS09090
gene id: 1790137:AXE80_RS09090
uniprot id: A0A1B1Y6M5
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS11690
gene id: 1790137:AXE80_RS11690
uniprot id: A0A1B1Y801
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

1790137:AXE80 RS10630
gene id: 1790137:AXE80_RS10630
uniprot id: A0A1B1Y7F7
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1790137:AXE80 RS07605
gene id: 1790137:AXE80_RS07605
uniprot id: A0A1B1Y5Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1790137:AXE80 RS13135
gene id: 1790137:AXE80_RS13135
uniprot id: A0A1B1Y8X6
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1790137:AXE80 RS02300
gene id: 1790137:AXE80_RS02300
uniprot id: A0A1B1Y328
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1790137:AXE80 RS08535
gene id: 1790137:AXE80_RS08535
uniprot id: A0A1B1Y6F2
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1790137:AXE80 RS12205
gene id: 1790137:AXE80_RS12205
uniprot id: A0A1B1Y891
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1790137:AXE80 RS09045
gene id: 1790137:AXE80_RS09045
uniprot id: A0A1B1Y6J8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1790137:AXE80 RS02975
gene id: 1790137:AXE80_RS02975
uniprot id: A0A1B1Y3H6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1790137:AXE80 RS01380
gene id: 1790137:AXE80_RS01380
uniprot id: A0A1B1Y2M8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1790137:AXE80 RS12775
gene id: 1790137:AXE80_RS12775
uniprot id: A0A1B1Y8J5
names: Similarity
messages: Belongs to the DtxR/MntR family.

1790137:AXE80 RS04125
gene id: 1790137:AXE80_RS04125
uniprot id: A0A1B1Y422
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1790137:AXE80 RS04260
gene id: 1790137:AXE80_RS04260
uniprot id: A0A1B1Y465
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1790137:AXE80 RS13200
gene id: 1790137:AXE80_RS13200
uniprot id: A0A1B1Y8T5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

1790137:AXE80 RS04330
gene id: 1790137:AXE80_RS04330
uniprot id: A0A1B1Y482
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS07565
gene id: 1790137:AXE80_RS07565
uniprot id: A0A1B1Y5V4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1790137:AXE80 RS11320
gene id: 1790137:AXE80_RS11320
uniprot id: A0A1B1Y7S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1790137:AXE80 RS05110
gene id: 1790137:AXE80_RS05110
uniprot id: A0A1B1Y4L0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1790137:AXE80 RS08890
gene id: 1790137:AXE80_RS08890
uniprot id: A0A1B1Y6J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS09745
gene id: 1790137:AXE80_RS09745
uniprot id: A0A1B1Y715
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1790137:AXE80 RS10520
gene id: 1790137:AXE80_RS10520
uniprot id: A0A1B1Y7E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1790137:AXE80 RS01175
gene id: 1790137:AXE80_RS01175
uniprot id: A0A1B1Y2I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1790137:AXE80 RS02760
gene id: 1790137:AXE80_RS02760
uniprot id: A0A1B1Y3D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1790137:AXE80 RS01330
gene id: 1790137:AXE80_RS01330
uniprot id: A0A1B1Y2L8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1790137:AXE80 RS09560
gene id: 1790137:AXE80_RS09560
uniprot id: A0A1B1Y6Y9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS05310
gene id: 1790137:AXE80_RS05310
uniprot id: A0A1B1Y4M3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1790137:AXE80 RS11055
gene id: 1790137:AXE80_RS11055
uniprot id: A0A1B1Y7R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1790137:AXE80 RS09785
gene id: 1790137:AXE80_RS09785
uniprot id: A0A1B1Y700
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1790137:AXE80 RS07810
gene id: 1790137:AXE80_RS07810
uniprot id: A0A1B1Y5Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1790137:AXE80 RS02955
gene id: 1790137:AXE80_RS02955
uniprot id: A0A1B1Y3I0
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS08090
gene id: 1790137:AXE80_RS08090
uniprot id: A0A1B1Y661
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS04060
gene id: 1790137:AXE80_RS04060
uniprot id: A0A1B1Y417
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1790137:AXE80 RS10590
gene id: 1790137:AXE80_RS10590
uniprot id: A0A1B1Y7H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1790137:AXE80 RS03065
gene id: 1790137:AXE80_RS03065
uniprot id: A0A1B1Y3L1
names: Similarity
messages: Belongs to the SCO1/2 family.

1790137:AXE80 RS12970
gene id: 1790137:AXE80_RS12970
uniprot id: A0A1B1Y8T7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS06845
gene id: 1790137:AXE80_RS06845
uniprot id: A0A1B1Y5F8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS10040
gene id: 1790137:AXE80_RS10040
uniprot id: A0A1B1Y784
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS01895
gene id: 1790137:AXE80_RS01895
uniprot id: A0A1B1Y2Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1790137:AXE80 RS09720
gene id: 1790137:AXE80_RS09720
uniprot id: A0A1B1Y718
names: Similarity
messages: Belongs to the pirin family.

1790137:AXE80 RS00180
gene id: 1790137:AXE80_RS00180
uniprot id: A0A1B1Y9C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1790137:AXE80 RS05325
gene id: 1790137:AXE80_RS05325
uniprot id: A0A1B1Y4Q8
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1790137:AXE80 RS11620
gene id: 1790137:AXE80_RS11620
uniprot id: A0A1B1Y827
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1790137:AXE80 RS08360
gene id: 1790137:AXE80_RS08360
uniprot id: A0A1B1Y688
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1790137:AXE80 RS06965
gene id: 1790137:AXE80_RS06965
uniprot id: A0A1B1Y5I1
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1790137:AXE80 RS12760
gene id: 1790137:AXE80_RS12760
uniprot id: A0A1B1Y8J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS01110
gene id: 1790137:AXE80_RS01110
uniprot id: A0A1B1Y2H5
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS12790
gene id: 1790137:AXE80_RS12790
uniprot id: A0A1B1Y8L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1790137:AXE80 RS13800
gene id: 1790137:AXE80_RS13800
uniprot id: A0A1B1Y991
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1790137:AXE80 RS10320
gene id: 1790137:AXE80_RS10320
uniprot id: A0A1B1Y785
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1790137:AXE80 RS04005
gene id: 1790137:AXE80_RS04005
uniprot id: A0A1B1Y3Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1790137:AXE80 RS10010
gene id: 1790137:AXE80_RS10010
uniprot id: A0A1B1Y750
names: Similarity
messages: Belongs to the catalase family.

1790137:AXE80 RS02615
gene id: 1790137:AXE80_RS02615
uniprot id: A0A1B1Y383
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1790137:AXE80 RS08210
gene id: 1790137:AXE80_RS08210
uniprot id: A0A1B1Y646
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1790137:AXE80 RS10450
gene id: 1790137:AXE80_RS10450
uniprot id: A0A1B1Y7F6
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1790137:AXE80 RS13270
gene id: 1790137:AXE80_RS13270
uniprot id: A0A1B1Y8V9
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS14065
gene id: 1790137:AXE80_RS14065
uniprot id: A0A1B1Y995
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1790137:AXE80 RS10655
gene id: 1790137:AXE80_RS10655
uniprot id: A0A1B1Y7E0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1790137:AXE80 RS04685
gene id: 1790137:AXE80_RS04685
uniprot id: A0A1B1Y4B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1790137:AXE80 RS11445
gene id: 1790137:AXE80_RS11445
uniprot id: A0A1B1Y9T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1790137:AXE80 RS04050
gene id: 1790137:AXE80_RS04050
uniprot id: A0A1B1Y425
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1790137:AXE80 RS09455
gene id: 1790137:AXE80_RS09455
uniprot id: A0A1B1Y6X0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1790137:AXE80 RS12030
gene id: 1790137:AXE80_RS12030
uniprot id: A0A1B1Y8A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1790137:AXE80 RS05165
gene id: 1790137:AXE80_RS05165
uniprot id: A0A1B1Y4L8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1790137:AXE80 RS01000
gene id: 1790137:AXE80_RS01000
uniprot id: A0A1B1Y2F4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1790137:AXE80 RS00355
gene id: 1790137:AXE80_RS00355
uniprot id: A0A1B1Y271
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS03690
gene id: 1790137:AXE80_RS03690
uniprot id: A0A1B1Y3U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS08615
gene id: 1790137:AXE80_RS08615
uniprot id: A0A1B1Y6C7
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1790137:AXE80 RS08730
gene id: 1790137:AXE80_RS08730
uniprot id: A0A1B1Y6J1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1790137:AXE80 RS06130
gene id: 1790137:AXE80_RS06130
uniprot id: A0A1B1Y558
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

1790137:AXE80 RS10425
gene id: 1790137:AXE80_RS10425
uniprot id: A0A1B1Y7E8
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1790137:AXE80 RS04865
gene id: 1790137:AXE80_RS04865
uniprot id: A0A1B1Y4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1790137:AXE80 RS04575
gene id: 1790137:AXE80_RS04575
uniprot id: A0A1B1Y499
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS02480
gene id: 1790137:AXE80_RS02480
uniprot id: A0A1B1Y395
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1790137:AXE80 RS13510
gene id: 1790137:AXE80_RS13510
uniprot id: A0A1B1Y8Y8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1790137:AXE80 RS09810
gene id: 1790137:AXE80_RS09810
uniprot id: A0A1B1Y6Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1790137:AXE80 RS10210
gene id: 1790137:AXE80_RS10210
uniprot id: A0A1B1Y782
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS00175
gene id: 1790137:AXE80_RS00175
uniprot id: A0A1B1Y209
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS05275
gene id: 1790137:AXE80_RS05275
uniprot id: A0A1B1Y4P7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1790137:AXE80 RS04740
gene id: 1790137:AXE80_RS04740
uniprot id: A0A1B1Y4F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1790137:AXE80 RS01420
gene id: 1790137:AXE80_RS01420
uniprot id: A0A1B1Y2N0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Secreted

1790137:AXE80 RS10180
gene id: 1790137:AXE80_RS10180
uniprot id: A0A1B1Y798
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1790137:AXE80 RS11385
gene id: 1790137:AXE80_RS11385
uniprot id: A0A1B1Y7U0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1790137:AXE80 RS14030
gene id: 1790137:AXE80_RS14030
uniprot id: A0A1B1Y981
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1790137:AXE80 RS13190
gene id: 1790137:AXE80_RS13190
uniprot id: A0A1B1Y8R9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1790137:AXE80 RS05855
gene id: 1790137:AXE80_RS05855
uniprot id: A0A1B1Y4X0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1790137:AXE80 RS00985
gene id: 1790137:AXE80_RS00985
uniprot id: A0A1B1Y2F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1790137:AXE80 RS00475
gene id: 1790137:AXE80_RS00475
uniprot id: A0A1B1Y287
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1790137:AXE80 RS00845
gene id: 1790137:AXE80_RS00845
uniprot id: A0A1B1Y2F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1790137:AXE80 RS12130
gene id: 1790137:AXE80_RS12130
uniprot id: A0A1B1Y8D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1790137:AXE80 RS01900
gene id: 1790137:AXE80_RS01900
uniprot id: A0A1B1Y2X0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1790137:AXE80 RS13285
gene id: 1790137:AXE80_RS13285
uniprot id: A0A1B1Y904
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1790137:AXE80 RS09175
gene id: 1790137:AXE80_RS09175
uniprot id: A0A1B1Y6N8
names: Similarity
messages: Belongs to the UPF0246 family.

1790137:AXE80 RS11935
gene id: 1790137:AXE80_RS11935
uniprot id: A0A1B1Y880
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1790137:AXE80 RS03135
gene id: 1790137:AXE80_RS03135
uniprot id: A0A1B1Y3I5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1790137:AXE80 RS11560
gene id: 1790137:AXE80_RS11560
uniprot id: A0A1B1Y7Z5
names: Similarity
messages: Belongs to the sulfatase family.

1790137:AXE80 RS03080
gene id: 1790137:AXE80_RS03080
uniprot id: A0A1B1Y3J8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1790137:AXE80 RS00650
gene id: 1790137:AXE80_RS00650
uniprot id: A0A1B1Y2B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1790137:AXE80 RS12470
gene id: 1790137:AXE80_RS12470
uniprot id: A0A1B1Y8G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1790137:AXE80 RS06065
gene id: 1790137:AXE80_RS06065
uniprot id: A0A1B1Y553
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1790137:AXE80 RS04025
gene id: 1790137:AXE80_RS04025
uniprot id: A0A1B1Y407
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1790137:AXE80 RS11665
gene id: 1790137:AXE80_RS11665
uniprot id: A0A1B1Y819
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1790137:AXE80 RS03800
gene id: 1790137:AXE80_RS03800
uniprot id: A0A1B1Y3V7
names: Similarity
messages: Belongs to the SusD family.

1790137:AXE80 RS00745
gene id: 1790137:AXE80_RS00745
uniprot id: A0A1B1Y2D1
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS11505
gene id: 1790137:AXE80_RS11505
uniprot id: A0A1B1Y7X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1790137:AXE80 RS11400
gene id: 1790137:AXE80_RS11400
uniprot id: A0A1B1Y7V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1790137:AXE80 RS06325
gene id: 1790137:AXE80_RS06325
uniprot id: A0A1B1Y576
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1790137:AXE80 RS09235
gene id: 1790137:AXE80_RS09235
uniprot id: A0A1B1Y6S8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1790137:AXE80 RS06640
gene id: 1790137:AXE80_RS06640
uniprot id: A0A1B1Y5D6
names: Similarity
messages: Belongs to the nitroreductase family.

1790137:AXE80 RS09515
gene id: 1790137:AXE80_RS09515
uniprot id: A0A1B1Y6U1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1790137:AXE80 RS00525
gene id: 1790137:AXE80_RS00525
uniprot id: A0A1B1Y2A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1790137:AXE80 RS08440
gene id: 1790137:AXE80_RS08440
uniprot id: A0A1B1Y6A9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1790137:AXE80 RS07580
gene id: 1790137:AXE80_RS07580
uniprot id: A0A1B1Y5V2
names: Similarity
messages: Belongs to the IMPACT family.

1790137:AXE80 RS08700
gene id: 1790137:AXE80_RS08700
uniprot id: A0A1B1Y6I1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1790137:AXE80 RS12580
gene id: 1790137:AXE80_RS12580
uniprot id: A0A1B1Y8H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1790137:AXE80 RS07555
gene id: 1790137:AXE80_RS07555
uniprot id: A0A1B1Y5X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1790137:AXE80 RS03855
gene id: 1790137:AXE80_RS03855
uniprot id: A0A1B1Y3Y1
names: Similarity
messages: Belongs to the peptidase S41A family.

1790137:AXE80 RS08980
gene id: 1790137:AXE80_RS08980
uniprot id: A0A1B1Y6K4
names: Similarity
messages: Belongs to the AIR synthase family.

1790137:AXE80 RS04855
gene id: 1790137:AXE80_RS04855
uniprot id: A0A1B1Y4E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1790137:AXE80 RS11765
gene id: 1790137:AXE80_RS11765
uniprot id: A0A1B1Y823
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1790137:AXE80 RS12585
gene id: 1790137:AXE80_RS12585
uniprot id: A0A1B1Y8M4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1790137:AXE80 RS12695
gene id: 1790137:AXE80_RS12695
uniprot id: A0A1B1Y8J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1790137:AXE80 RS09610
gene id: 1790137:AXE80_RS09610
uniprot id: A0A1B1Y6Z5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1790137:AXE80 RS04755
gene id: 1790137:AXE80_RS04755
uniprot id: A0A1B1Y4C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1790137:AXE80 RS02435
gene id: 1790137:AXE80_RS02435
uniprot id: A0A1B1Y3A2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1790137:AXE80 RS04790
gene id: 1790137:AXE80_RS04790
uniprot id: A0A1B1Y9H6
names: Similarity
messages: Belongs to the DEAD box helicase family.

1790137:AXE80 RS11265
gene id: 1790137:AXE80_RS11265
uniprot id: A0A1B1Y7R5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS11495
gene id: 1790137:AXE80_RS11495
uniprot id: A0A1B1Y7Z9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1790137:AXE80 RS13870
gene id: 1790137:AXE80_RS13870
uniprot id: A0A1B1Y951
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1790137:AXE80 RS11950
gene id: 1790137:AXE80_RS11950
uniprot id: A0A1B1Y858
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1790137:AXE80 RS06680
gene id: 1790137:AXE80_RS06680
uniprot id: A0A1B1Y5F0
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS00030
gene id: 1790137:AXE80_RS00030
uniprot id: A0A1B1Y206
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1790137:AXE80 RS06240
gene id: 1790137:AXE80_RS06240
uniprot id: A0A1B1Y579
names: Subcellular Location Annotation
messages: Membrane

1790137:AXE80 RS13815
gene id: 1790137:AXE80_RS13815
uniprot id: A0A1B1Y944
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1790137:AXE80 RS04475
gene id: 1790137:AXE80_RS04475
uniprot id: A0A1B1Y497
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1790137:AXE80 RS01985
gene id: 1790137:AXE80_RS01985
uniprot id: A0A1B1Y2Z5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1790137:AXE80 RS13990
gene id: 1790137:AXE80_RS13990
uniprot id: A0A1B1Y9A8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1790137:AXE80 RS01715
gene id: 1790137:AXE80_RS01715
uniprot id: A0A1B1Y2V5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1790137:AXE80 RS07910
gene id: 1790137:AXE80_RS07910
uniprot id: A0A1B1Y612
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1790137:AXE80 RS01225
gene id: 1790137:AXE80_RS01225
uniprot id: A0A1B1Y2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1790137:AXE80 RS03680
gene id: 1790137:AXE80_RS03680
uniprot id: A0A1B1Y3U7
names: Similarity
messages: Belongs to the P(II) protein family.

1790137:AXE80 RS01395
gene id: 1790137:AXE80_RS01395
uniprot id: A0A1B1Y2R8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1790137:AXE80 RS07735
gene id: 1790137:AXE80_RS07735
uniprot id: A0A1B1Y5Y5
names: Similarity
messages: Belongs to the DEAD box helicase family.