1789224:BFG52 RS13670
gene id: 1789224:BFG52_RS13670
uniprot id: A0A1B2M2A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1789224:BFG52 RS11500
gene id: 1789224:BFG52_RS11500
uniprot id: A0A1B2M160
names: Similarity
messages: Belongs to the aspartokinase family.

1789224:BFG52 RS14890
gene id: 1789224:BFG52_RS14890
uniprot id: A0A1B2M2U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1789224:BFG52 RS10490
gene id: 1789224:BFG52_RS10490
uniprot id: A0A1B2M0N4
names: Similarity
messages: Belongs to the peptidase M16 family.

1789224:BFG52 RS05900
gene id: 1789224:BFG52_RS05900
uniprot id: A0A1B2LYH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1789224:BFG52 RS13285
gene id: 1789224:BFG52_RS13285
uniprot id: A0A1B2M213
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1789224:BFG52 RS03975
gene id: 1789224:BFG52_RS03975
uniprot id: A0A1B2LXV4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1789224:BFG52 RS03970
gene id: 1789224:BFG52_RS03970
uniprot id: A0A1B2LXA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

1789224:BFG52 RS00595
gene id: 1789224:BFG52_RS00595
uniprot id: A0A1B2LVM8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1789224:BFG52 RS00160
gene id: 1789224:BFG52_RS00160
uniprot id: A0A1B2LVI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1789224:BFG52 RS04215
gene id: 1789224:BFG52_RS04215
uniprot id: A0A1B2LXG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1789224:BFG52 RS12590
gene id: 1789224:BFG52_RS12590
uniprot id: A0A1B2M1N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1789224:BFG52 RS05325
gene id: 1789224:BFG52_RS05325
uniprot id: A0A1B2LY70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS16450
gene id: 1789224:BFG52_RS16450
uniprot id: A0A1B2M411
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

1789224:BFG52 RS04120
gene id: 1789224:BFG52_RS04120
uniprot id: A0A1B2LXG3
names: Similarity
messages: Belongs to the UPF0145 family.

1789224:BFG52 RS13200
gene id: 1789224:BFG52_RS13200
uniprot id: A0A1B2M224
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1789224:BFG52 RS04025
gene id: 1789224:BFG52_RS04025
uniprot id: A0A1B2LXW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1789224:BFG52 RS08900
gene id: 1789224:BFG52_RS08900
uniprot id: A0A1B2LZW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS01805
gene id: 1789224:BFG52_RS01805
uniprot id: A0A1B2LW95
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS10580
gene id: 1789224:BFG52_RS10580
uniprot id: A0A1B2M0N8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS02720
gene id: 1789224:BFG52_RS02720
uniprot id: A0A1B2LWQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1789224:BFG52 RS15120
gene id: 1789224:BFG52_RS15120
uniprot id: A0A1B2M2Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1789224:BFG52 RS02245
gene id: 1789224:BFG52_RS02245
uniprot id: A0A1B2LWF8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1789224:BFG52 RS12565
gene id: 1789224:BFG52_RS12565
uniprot id: A0A1B2M254
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1789224:BFG52 RS02085
gene id: 1789224:BFG52_RS02085
uniprot id: A0A1B2LWD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1789224:BFG52 RS04885
gene id: 1789224:BFG52_RS04885
uniprot id: A0A1B2LXT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS05915
gene id: 1789224:BFG52_RS05915
uniprot id: A0A1B2LY96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS08605
gene id: 1789224:BFG52_RS08605
uniprot id: A0A1B2LZM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS00880
gene id: 1789224:BFG52_RS00880
uniprot id: A0A1B2LVT7
names: Subcellular Location Annotation
messages: Cytoplasm

1789224:BFG52 RS11510
gene id: 1789224:BFG52_RS11510
uniprot id: A0A1B2M144
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1789224:BFG52 RS10700
gene id: 1789224:BFG52_RS10700
uniprot id: A0A1B2M0T0
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS03300
gene id: 1789224:BFG52_RS03300
uniprot id: A0A1B2LXH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS16225
gene id: 1789224:BFG52_RS16225
uniprot id: A0A1B2M3G3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1789224:BFG52 RS04685
gene id: 1789224:BFG52_RS04685
uniprot id: A0A1B2LXM6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1789224:BFG52 RS04915
gene id: 1789224:BFG52_RS04915
uniprot id: A0A1B2LYA9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS12305
gene id: 1789224:BFG52_RS12305
uniprot id: A0A1B2M1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS05020
gene id: 1789224:BFG52_RS05020
uniprot id: A0A1B2LXV7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1789224:BFG52 RS10365
gene id: 1789224:BFG52_RS10365
uniprot id: A0A1B2M0I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS15665
gene id: 1789224:BFG52_RS15665
uniprot id: A0A1B2M3C8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1789224:BFG52 RS01000
gene id: 1789224:BFG52_RS01000
uniprot id: A0A1B2LVV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1789224:BFG52 RS15035
gene id: 1789224:BFG52_RS15035
uniprot id: A0A1B2M2W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1789224:BFG52 RS00360
gene id: 1789224:BFG52_RS00360
uniprot id: A0A1B2LVK4
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS13685
gene id: 1789224:BFG52_RS13685
uniprot id: A0A1B2M289
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1789224:BFG52 RS05890
gene id: 1789224:BFG52_RS05890
uniprot id: A0A1B2LYA2
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

1789224:BFG52 RS17260
gene id: 1789224:BFG52_RS17260
uniprot id: A0A1B2LY48
names: Subcellular Location Annotation
messages: Cell surface

1789224:BFG52 RS00210
gene id: 1789224:BFG52_RS00210
uniprot id: A0A1B2LVJ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS01160
gene id: 1789224:BFG52_RS01160
uniprot id: A0A1B2LWF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS06910
gene id: 1789224:BFG52_RS06910
uniprot id: A0A1B2LYU0
names: Similarity
messages: Belongs to the MQO family.

1789224:BFG52 RS05335
gene id: 1789224:BFG52_RS05335
uniprot id: A0A1B2LY18
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS13180
gene id: 1789224:BFG52_RS13180
uniprot id: A0A1B2M1Z0
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1789224:BFG52 RS09180
gene id: 1789224:BFG52_RS09180
uniprot id: A0A1B2M0F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1789224:BFG52 RS13820
gene id: 1789224:BFG52_RS13820
uniprot id: A0A1B2M2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS12595
gene id: 1789224:BFG52_RS12595
uniprot id: A0A1B2M1P1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1789224:BFG52 RS01970
gene id: 1789224:BFG52_RS01970
uniprot id: A0A1B2LWB6
names: Similarity
messages: Belongs to the LOG family.

1789224:BFG52 RS05090
gene id: 1789224:BFG52_RS05090
uniprot id: A0A1B2LXW7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS02590
gene id: 1789224:BFG52_RS02590
uniprot id: A0A1B2LX46
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1789224:BFG52 RS04235
gene id: 1789224:BFG52_RS04235
uniprot id: A0A1B2LXH8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1789224:BFG52 RS06045
gene id: 1789224:BFG52_RS06045
uniprot id: A0A1B2M406
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1789224:BFG52 RS06305
gene id: 1789224:BFG52_RS06305
uniprot id: A0A1B2LYI3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS10395
gene id: 1789224:BFG52_RS10395
uniprot id: A0A1B2M0M5
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS07185
gene id: 1789224:BFG52_RS07185
uniprot id: A0A1B2M3Y1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS11525
gene id: 1789224:BFG52_RS11525
uniprot id: A0A1B2M176
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS00830
gene id: 1789224:BFG52_RS00830
uniprot id: A0A1B2LVR4
names: Similarity
messages: Belongs to the GST superfamily.

1789224:BFG52 RS10285
gene id: 1789224:BFG52_RS10285
uniprot id: A0A1B2M110
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS11935
gene id: 1789224:BFG52_RS11935
uniprot id: A0A1B2M1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS02090
gene id: 1789224:BFG52_RS02090
uniprot id: A0A1B2LWW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1789224:BFG52 RS14505
gene id: 1789224:BFG52_RS14505
uniprot id: A0A1B2M2N6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1789224:BFG52 RS03385
gene id: 1789224:BFG52_RS03385
uniprot id: A0A1B2LX65
names: Similarity
messages: Belongs to the TrpF family.

1789224:BFG52 RS05510
gene id: 1789224:BFG52_RS05510
uniprot id: A0A1B2LYK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS06495
gene id: 1789224:BFG52_RS06495
uniprot id: A0A1B2M3X0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS15755
gene id: 1789224:BFG52_RS15755
uniprot id: A0A1B2M3A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1789224:BFG52 RS06245
gene id: 1789224:BFG52_RS06245
uniprot id: A0A1B2LYG3
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1789224:BFG52 RS11955
gene id: 1789224:BFG52_RS11955
uniprot id: A0A1B2M1U6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS14640
gene id: 1789224:BFG52_RS14640
uniprot id: A0A1B2M363
names: Similarity
messages: Belongs to the RelA/SpoT family.

1789224:BFG52 RS01055
gene id: 1789224:BFG52_RS01055
uniprot id: A0A1B2LVX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1789224:BFG52 RS03210
gene id: 1789224:BFG52_RS03210
uniprot id: A0A1B2LWZ5
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1789224:BFG52 RS05960
gene id: 1789224:BFG52_RS05960
uniprot id: A0A1B2LYI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1789224:BFG52 RS08715
gene id: 1789224:BFG52_RS08715
uniprot id: A0A1B2LZP7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1789224:BFG52 RS04060
gene id: 1789224:BFG52_RS04060
uniprot id: A0A1B2LXJ4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1789224:BFG52 RS00840
gene id: 1789224:BFG52_RS00840
uniprot id: A0A1B2LWA0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1789224:BFG52 RS01390
gene id: 1789224:BFG52_RS01390
uniprot id: A0A1B2LW24
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1789224:BFG52 RS15695
gene id: 1789224:BFG52_RS15695
uniprot id: A0A1B2M376
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1789224:BFG52 RS08330
gene id: 1789224:BFG52_RS08330
uniprot id: A0A1B2LZM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS08400
gene id: 1789224:BFG52_RS08400
uniprot id: A0A1B2LZN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS15760
gene id: 1789224:BFG52_RS15760
uniprot id: A0A1B2M386
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1789224:BFG52 RS11690
gene id: 1789224:BFG52_RS11690
uniprot id: A0A1B2M171
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS10370
gene id: 1789224:BFG52_RS10370
uniprot id: A0A1B2M0I9
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS08535
gene id: 1789224:BFG52_RS08535
uniprot id: A0A1B2LZM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS09290
gene id: 1789224:BFG52_RS09290
uniprot id: A0A1B2M005
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS03310
gene id: 1789224:BFG52_RS03310
uniprot id: A0A1B2LX13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS10075
gene id: 1789224:BFG52_RS10075
uniprot id: A0A1B2M0D7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1789224:BFG52 RS12110
gene id: 1789224:BFG52_RS12110
uniprot id: A0A1B2M1J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1789224:BFG52 RS00690
gene id: 1789224:BFG52_RS00690
uniprot id: A0A1B2LVR1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1789224:BFG52 RS09070
gene id: 1789224:BFG52_RS09070
uniprot id: A0A1B2LZW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1789224:BFG52 RS06620
gene id: 1789224:BFG52_RS06620
uniprot id: A0A1B2LYQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1789224:BFG52 RS01680
gene id: 1789224:BFG52_RS01680
uniprot id: A0A1B2LW78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1789224:BFG52 RS05670
gene id: 1789224:BFG52_RS05670
uniprot id: A0A1B2LYC9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1789224:BFG52 RS00540
gene id: 1789224:BFG52_RS00540
uniprot id: A0A1B2LVL9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1789224:BFG52 RS14480
gene id: 1789224:BFG52_RS14480
uniprot id: A0A1B2M2M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1789224:BFG52 RS03575
gene id: 1789224:BFG52_RS03575
uniprot id: A0A1B2LX34
names: Similarity
messages: Belongs to the YjdM family.

1789224:BFG52 RS04820
gene id: 1789224:BFG52_RS04820
uniprot id: A0A1B2LXS1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS10900
gene id: 1789224:BFG52_RS10900
uniprot id: A0A1B2M0V0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS10320
gene id: 1789224:BFG52_RS10320
uniprot id: A0A1B2M0K3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1789224:BFG52 RS10905
gene id: 1789224:BFG52_RS10905
uniprot id: A0A1B2M0S5
names: Similarity
messages: Belongs to the YkuD family.

1789224:BFG52 RS03630
gene id: 1789224:BFG52_RS03630
uniprot id: A0A1B2LX44
names: Similarity
messages: Belongs to the peptidase M24B family.

1789224:BFG52 RS00945
gene id: 1789224:BFG52_RS00945
uniprot id: A0A1B2LVU7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1789224:BFG52 RS01925
gene id: 1789224:BFG52_RS01925
uniprot id: A0A1B2LWT5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1789224:BFG52 RS04710
gene id: 1789224:BFG52_RS04710
uniprot id: A0A1B2LXQ6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1789224:BFG52 RS15045
gene id: 1789224:BFG52_RS15045
uniprot id: A0A1B2M2Y0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1789224:BFG52 RS10525
gene id: 1789224:BFG52_RS10525
uniprot id: A0A1B2M0L5
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS12535
gene id: 1789224:BFG52_RS12535
uniprot id: A0A1B2M1M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1789224:BFG52 RS02985
gene id: 1789224:BFG52_RS02985
uniprot id: A0A1B2LWU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS02225
gene id: 1789224:BFG52_RS02225
uniprot id: A0A1B2LWG6
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1789224:BFG52 RS03670
gene id: 1789224:BFG52_RS03670
uniprot id: A0A1B2LXC9
names: Similarity
messages: Belongs to the MipA/OmpV family.

1789224:BFG52 RS11780
gene id: 1789224:BFG52_RS11780
uniprot id: A0A1B2M184
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1789224:BFG52 RS06070
gene id: 1789224:BFG52_RS06070
uniprot id: A0A1B2LYF3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1789224:BFG52 RS12980
gene id: 1789224:BFG52_RS12980
uniprot id: A0A1B2M1V9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1789224:BFG52 RS03635
gene id: 1789224:BFG52_RS03635
uniprot id: A0A1B2LXP7
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1789224:BFG52 RS06235
gene id: 1789224:BFG52_RS06235
uniprot id: A0A1B2LYH9
names: Similarity
messages: Belongs to the GARS family.

1789224:BFG52 RS06205
gene id: 1789224:BFG52_RS06205
uniprot id: A0A1B2M433
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1789224:BFG52 RS09395
gene id: 1789224:BFG52_RS09395
uniprot id: A0A1B2M0J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS12715
gene id: 1789224:BFG52_RS12715
uniprot id: A0A1B2M1Q4
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS13190
gene id: 1789224:BFG52_RS13190
uniprot id: A0A1B2M1Z4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS11320
gene id: 1789224:BFG52_RS11320
uniprot id: A0A1B2M103
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS01220
gene id: 1789224:BFG52_RS01220
uniprot id: A0A1B2LVZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1789224:BFG52 RS07040
gene id: 1789224:BFG52_RS07040
uniprot id: A0A1B2LZD0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1789224:BFG52 RS07095
gene id: 1789224:BFG52_RS07095
uniprot id: A0A1B2LYV5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS15430
gene id: 1789224:BFG52_RS15430
uniprot id: A0A1B2M323
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS14650
gene id: 1789224:BFG52_RS14650
uniprot id: A0A1B2M2P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1789224:BFG52 RS01545
gene id: 1789224:BFG52_RS01545
uniprot id: A0A1B2LWL9
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS03465
gene id: 1789224:BFG52_RS03465
uniprot id: A0A1B2LX40
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1789224:BFG52 RS09585
gene id: 1789224:BFG52_RS09585
uniprot id: A0A1B2M083
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1789224:BFG52 RS03725
gene id: 1789224:BFG52_RS03725
uniprot id: A0A1B2LXD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS06350
gene id: 1789224:BFG52_RS06350
uniprot id: A0A1B2LYH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1789224:BFG52 RS12000
gene id: 1789224:BFG52_RS12000
uniprot id: A0A1B2M1H1
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS12265
gene id: 1789224:BFG52_RS12265
uniprot id: A0A1B2M1H3
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1789224:BFG52 RS10030
gene id: 1789224:BFG52_RS10030
uniprot id: A0A1B2M0D3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS01910
gene id: 1789224:BFG52_RS01910
uniprot id: A0A1B2LWA1
names: Subunit
messages: Homodimer.

1789224:BFG52 RS10170
gene id: 1789224:BFG52_RS10170
uniprot id: A0A1B2M0G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1789224:BFG52 RS11540
gene id: 1789224:BFG52_RS11540
uniprot id: A0A1B2M188
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS12530
gene id: 1789224:BFG52_RS12530
uniprot id: A0A1B2M1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1789224:BFG52 RS04480
gene id: 1789224:BFG52_RS04480
uniprot id: A0A1B2LXK9
names: Subunit
messages: Homodimer.

1789224:BFG52 RS08740
gene id: 1789224:BFG52_RS08740
uniprot id: A0A1B2LZQ4
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1789224:BFG52 RS01915
gene id: 1789224:BFG52_RS01915
uniprot id: A0A1B2LWB4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1789224:BFG52 RS14040
gene id: 1789224:BFG52_RS14040
uniprot id: A0A1B2M2D6
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS03480
gene id: 1789224:BFG52_RS03480
uniprot id: A0A1B2LX43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1789224:BFG52 RS07110
gene id: 1789224:BFG52_RS07110
uniprot id: A0A1B2LYY7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS00055
gene id: 1789224:BFG52_RS00055
uniprot id: A0A1B2LVF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1789224:BFG52 RS05060
gene id: 1789224:BFG52_RS05060
uniprot id: A0A1B2LXW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1789224:BFG52 RS08335
gene id: 1789224:BFG52_RS08335
uniprot id: A0A1B2LZI3
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1789224:BFG52 RS15585
gene id: 1789224:BFG52_RS15585
uniprot id: A0A1B2M353
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1789224:BFG52 RS04450
gene id: 1789224:BFG52_RS04450
uniprot id: A0A1B2LXJ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS15205
gene id: 1789224:BFG52_RS15205
uniprot id: A0A1B2M2Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1789224:BFG52 RS02140
gene id: 1789224:BFG52_RS02140
uniprot id: A0A1B2LWX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1789224:BFG52 RS02115
gene id: 1789224:BFG52_RS02115
uniprot id: A0A1B2LWE6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1789224:BFG52 RS06940
gene id: 1789224:BFG52_RS06940
uniprot id: A0A1B2LZB7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1789224:BFG52 RS02675
gene id: 1789224:BFG52_RS02675
uniprot id: A0A1B2LWV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1789224:BFG52 RS09345
gene id: 1789224:BFG52_RS09345
uniprot id: A0A1B2M0I1
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1789224:BFG52 RS03475
gene id: 1789224:BFG52_RS03475
uniprot id: A0A1B2LX50
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

1789224:BFG52 RS08640
gene id: 1789224:BFG52_RS08640
uniprot id: A0A1B2LZQ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS01170
gene id: 1789224:BFG52_RS01170
uniprot id: A0A1B2LVZ0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1789224:BFG52 RS01330
gene id: 1789224:BFG52_RS01330
uniprot id: A0A1B2LW15
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1789224:BFG52 RS12680
gene id: 1789224:BFG52_RS12680
uniprot id: A0A1B2M1Q9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1789224:BFG52 RS05240
gene id: 1789224:BFG52_RS05240
uniprot id: A0A1B2LXZ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS02120
gene id: 1789224:BFG52_RS02120
uniprot id: A0A1B2LWK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1789224:BFG52 RS08815
gene id: 1789224:BFG52_RS08815
uniprot id: A0A1B2LZS3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1789224:BFG52 RS02875
gene id: 1789224:BFG52_RS02875
uniprot id: A0A1B2M3Q8
names: Subcellular Location Annotation
messages: Cell inner membrane

1789224:BFG52 RS15690
gene id: 1789224:BFG52_RS15690
uniprot id: A0A1B2M370
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1789224:BFG52 RS04265
gene id: 1789224:BFG52_RS04265
uniprot id: A0A1B2LXI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1789224:BFG52 RS02865
gene id: 1789224:BFG52_RS02865
uniprot id: A0A1B2LWU0
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1789224:BFG52 RS06865
gene id: 1789224:BFG52_RS06865
uniprot id: A0A1B2LYU9
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS15845
gene id: 1789224:BFG52_RS15845
uniprot id: A0A1B2M397
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS11030
gene id: 1789224:BFG52_RS11030
uniprot id: A0A1B2M0Z8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS14405
gene id: 1789224:BFG52_RS14405
uniprot id: A0A1B2M2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1789224:BFG52 RS13000
gene id: 1789224:BFG52_RS13000
uniprot id: A0A1B2M1Y7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1789224:BFG52 RS00235
gene id: 1789224:BFG52_RS00235
uniprot id: A0A1B2LVJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1789224:BFG52 RS02510
gene id: 1789224:BFG52_RS02510
uniprot id: A0A1B2LWS2
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1789224:BFG52 RS00750
gene id: 1789224:BFG52_RS00750
uniprot id: A0A1B2LVR9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS04780
gene id: 1789224:BFG52_RS04780
uniprot id: A0A1B2LXR1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS08350
gene id: 1789224:BFG52_RS08350
uniprot id: A0A1B2LZZ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1789224:BFG52 RS10620
gene id: 1789224:BFG52_RS10620
uniprot id: A0A1B2M0M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1789224:BFG52 RS00800
gene id: 1789224:BFG52_RS00800
uniprot id: A0A1B2LVS2
names: Similarity
messages: Belongs to the sulfatase family.

1789224:BFG52 RS00170
gene id: 1789224:BFG52_RS00170
uniprot id: A0A1B2LVI3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1789224:BFG52 RS06560
gene id: 1789224:BFG52_RS06560
uniprot id: A0A1B2LYN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1789224:BFG52 RS15090
gene id: 1789224:BFG52_RS15090
uniprot id: A0A1B2M2X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1789224:BFG52 RS10035
gene id: 1789224:BFG52_RS10035
uniprot id: A0A1B2M0F1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1789224:BFG52 RS11890
gene id: 1789224:BFG52_RS11890
uniprot id: A0A1B2M1B1
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1789224:BFG52 RS16390
gene id: 1789224:BFG52_RS16390
uniprot id: A0A1B2M3Q6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1789224:BFG52 RS12390
gene id: 1789224:BFG52_RS12390
uniprot id: A0A1B2M1P2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS14045
gene id: 1789224:BFG52_RS14045
uniprot id: A0A1B2M2F4
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS14075
gene id: 1789224:BFG52_RS14075
uniprot id: A0A1B2M2F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1789224:BFG52 RS15780
gene id: 1789224:BFG52_RS15780
uniprot id: A0A1B2M3A9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1789224:BFG52 RS04875
gene id: 1789224:BFG52_RS04875
uniprot id: A0A1B2LXV0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS00555
gene id: 1789224:BFG52_RS00555
uniprot id: A0A1B2LVQ4
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS06745
gene id: 1789224:BFG52_RS06745
uniprot id: A0A1B2LYW1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS09810
gene id: 1789224:BFG52_RS09810
uniprot id: A0A1B2M091
names: Similarity
messages: Belongs to the peptidase M16 family.

1789224:BFG52 RS01900
gene id: 1789224:BFG52_RS01900
uniprot id: A0A1B2LW99
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS10230
gene id: 1789224:BFG52_RS10230
uniprot id: A0A1B2M0F9
names: Similarity
messages: Belongs to the HSP15 family.

1789224:BFG52 RS11915
gene id: 1789224:BFG52_RS11915
uniprot id: A0A1B2M1C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1789224:BFG52 RS13265
gene id: 1789224:BFG52_RS13265
uniprot id: A0A1B2M219
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1789224:BFG52 RS05595
gene id: 1789224:BFG52_RS05595
uniprot id: A0A1B2LY66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1789224:BFG52 RS01595
gene id: 1789224:BFG52_RS01595
uniprot id: A0A1B2LWM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1789224:BFG52 RS06040
gene id: 1789224:BFG52_RS06040
uniprot id: A0A1B2LYD2
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1789224:BFG52 RS13975
gene id: 1789224:BFG52_RS13975
uniprot id: A0A1B2M2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1789224:BFG52 RS04465
gene id: 1789224:BFG52_RS04465
uniprot id: A0A1B2LXN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1789224:BFG52 RS04850
gene id: 1789224:BFG52_RS04850
uniprot id: A0A1B2LXU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS12955
gene id: 1789224:BFG52_RS12955
uniprot id: A0A1B2M1Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1789224:BFG52 RS15025
gene id: 1789224:BFG52_RS15025
uniprot id: A0A1B2M2V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1789224:BFG52 RS05430
gene id: 1789224:BFG52_RS05430
uniprot id: A0A1B2LY90
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1789224:BFG52 RS06475
gene id: 1789224:BFG52_RS06475
uniprot id: A0A1B2LYM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1789224:BFG52 RS06980
gene id: 1789224:BFG52_RS06980
uniprot id: A0A1B2LYX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1789224:BFG52 RS05385
gene id: 1789224:BFG52_RS05385
uniprot id: A0A1B2LY23
names: Similarity
messages: Belongs to the UPF0178 family.

1789224:BFG52 RS11950
gene id: 1789224:BFG52_RS11950
uniprot id: A0A1B2M1C2
names: Similarity
messages: Belongs to the group II decarboxylase family.

1789224:BFG52 RS14510
gene id: 1789224:BFG52_RS14510
uniprot id: A0A1B2M2L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS08425
gene id: 1789224:BFG52_RS08425
uniprot id: A0A1B2LZK3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1789224:BFG52 RS10935
gene id: 1789224:BFG52_RS10935
uniprot id: A0A1B2M0T7
names: Similarity
messages: Belongs to the TrpC family.

1789224:BFG52 RS00285
gene id: 1789224:BFG52_RS00285
uniprot id: A0A1B2LVK5
names: Similarity
messages: Belongs to the UPF0260 family.

1789224:BFG52 RS09080
gene id: 1789224:BFG52_RS09080
uniprot id: A0A1B2LZX1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1789224:BFG52 RS13370
gene id: 1789224:BFG52_RS13370
uniprot id: A0A1B2M241
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1789224:BFG52 RS15745
gene id: 1789224:BFG52_RS15745
uniprot id: A0A1B2M385
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1789224:BFG52 RS01930
gene id: 1789224:BFG52_RS01930
uniprot id: A0A1B2LWD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS15230
gene id: 1789224:BFG52_RS15230
uniprot id: A0A1B2M3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1789224:BFG52 RS10255
gene id: 1789224:BFG52_RS10255
uniprot id: A0A1B2M0J3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1789224:BFG52 RS10055
gene id: 1789224:BFG52_RS10055
uniprot id: A0A1B2M0E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1789224:BFG52 RS15555
gene id: 1789224:BFG52_RS15555
uniprot id: A0A1B2M361
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1789224:BFG52 RS09945
gene id: 1789224:BFG52_RS09945
uniprot id: A0A1B2M0C7
names: Similarity
messages: Belongs to the Gfa family.

1789224:BFG52 RS05255
gene id: 1789224:BFG52_RS05255
uniprot id: A0A1B2LXZ6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1789224:BFG52 RS14825
gene id: 1789224:BFG52_RS14825
uniprot id: A0A1B2M2S1
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS00425
gene id: 1789224:BFG52_RS00425
uniprot id: A0A1B2LVJ7
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

1789224:BFG52 RS11555
gene id: 1789224:BFG52_RS11555
uniprot id: A0A1B2M150
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS12490
gene id: 1789224:BFG52_RS12490
uniprot id: A0A1B2M1M0
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1789224:BFG52 RS02850
gene id: 1789224:BFG52_RS02850
uniprot id: A0A1B2LX96
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS12890
gene id: 1789224:BFG52_RS12890
uniprot id: A0A1B2M1U5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1789224:BFG52 RS15705
gene id: 1789224:BFG52_RS15705
uniprot id: A0A1B2M390
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1789224:BFG52 RS02715
gene id: 1789224:BFG52_RS02715
uniprot id: A0A1B2LWR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1789224:BFG52 RS16380
gene id: 1789224:BFG52_RS16380
uniprot id: A0A1B2M3M7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1789224:BFG52 RS08860
gene id: 1789224:BFG52_RS08860
uniprot id: A0A1B2LZT4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1789224:BFG52 RS05760
gene id: 1789224:BFG52_RS05760
uniprot id: A0A1B2LY81
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1789224:BFG52 RS00770
gene id: 1789224:BFG52_RS00770
uniprot id: A0A1B2LVQ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS11335
gene id: 1789224:BFG52_RS11335
uniprot id: A0A1B2M114
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1789224:BFG52 RS04650
gene id: 1789224:BFG52_RS04650
uniprot id: A0A1B2LXQ9
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS05730
gene id: 1789224:BFG52_RS05730
uniprot id: A0A1B2LY87
names: Similarity
messages: Belongs to the YciI family.

1789224:BFG52 RS02160
gene id: 1789224:BFG52_RS02160
uniprot id: A0A1B2LWG3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1789224:BFG52 RS02320
gene id: 1789224:BFG52_RS02320
uniprot id: A0A1B2LWJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

1789224:BFG52 RS00950
gene id: 1789224:BFG52_RS00950
uniprot id: A0A1B2LVU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS07150
gene id: 1789224:BFG52_RS07150
uniprot id: A0A1B2LZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1789224:BFG52 RS01605
gene id: 1789224:BFG52_RS01605
uniprot id: A0A1B2M3T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1789224:BFG52 RS03485
gene id: 1789224:BFG52_RS03485
uniprot id: A0A1B2M3W8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

1789224:BFG52 RS02010
gene id: 1789224:BFG52_RS02010
uniprot id: A0A1B2LWB9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1789224:BFG52 RS02410
gene id: 1789224:BFG52_RS02410
uniprot id: A0A1B2LWJ7
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS12795
gene id: 1789224:BFG52_RS12795
uniprot id: A0A1B2M1W0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1789224:BFG52 RS05880
gene id: 1789224:BFG52_RS05880
uniprot id: A0A1B2M4B7
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS00805
gene id: 1789224:BFG52_RS00805
uniprot id: A0A1B2LVS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1789224:BFG52 RS11165
gene id: 1789224:BFG52_RS11165
uniprot id: A0A1B2M101
names: Similarity
messages: Belongs to the TPP enzyme family.

1789224:BFG52 RS11570
gene id: 1789224:BFG52_RS11570
uniprot id: A0A1B2M153
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1789224:BFG52 RS04175
gene id: 1789224:BFG52_RS04175
uniprot id: A0A1B2LXH1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS10355
gene id: 1789224:BFG52_RS10355
uniprot id: A0A1B2M0I0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS08600
gene id: 1789224:BFG52_RS08600
uniprot id: A0A1B2LZQ5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1789224:BFG52 RS03980
gene id: 1789224:BFG52_RS03980
uniprot id: A0A1B2LXB9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1789224:BFG52 RS14900
gene id: 1789224:BFG52_RS14900
uniprot id: A0A1B2M2S7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1789224:BFG52 RS09685
gene id: 1789224:BFG52_RS09685
uniprot id: A0A1B2M097
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1789224:BFG52 RS12985
gene id: 1789224:BFG52_RS12985
uniprot id: A0A1B2M1V7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1789224:BFG52 RS14300
gene id: 1789224:BFG52_RS14300
uniprot id: A0A1B2M2J4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1789224:BFG52 RS00205
gene id: 1789224:BFG52_RS00205
uniprot id: A0A1B2LVK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS14950
gene id: 1789224:BFG52_RS14950
uniprot id: A0A1B2M2T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1789224:BFG52 RS09995
gene id: 1789224:BFG52_RS09995
uniprot id: A0A1B2M0D9
names: Similarity
messages: Belongs to the Skp family.

1789224:BFG52 RS02860
gene id: 1789224:BFG52_RS02860
uniprot id: A0A1B2LWU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1789224:BFG52 RS14565
gene id: 1789224:BFG52_RS14565
uniprot id: A0A1B2M2T0
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS05700
gene id: 1789224:BFG52_RS05700
uniprot id: A0A1B2LY92
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1789224:BFG52 RS06580
gene id: 1789224:BFG52_RS06580
uniprot id: A0A1B2LYT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS09700
gene id: 1789224:BFG52_RS09700
uniprot id: A0A1B2M090
names: Similarity
messages: Belongs to the universal stress protein A family.

1789224:BFG52 RS15190
gene id: 1789224:BFG52_RS15190
uniprot id: A0A1B2M2Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1789224:BFG52 RS12845
gene id: 1789224:BFG52_RS12845
uniprot id: A0A1B2M1S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1789224:BFG52 RS12965
gene id: 1789224:BFG52_RS12965
uniprot id: A0A1B2M1V2
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1789224:BFG52 RS13345
gene id: 1789224:BFG52_RS13345
uniprot id: A0A1B2M230
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1789224:BFG52 RS12125
gene id: 1789224:BFG52_RS12125
uniprot id: A0A1B2M1E9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1789224:BFG52 RS14800
gene id: 1789224:BFG52_RS14800
uniprot id: A0A1B2M2X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS08875
gene id: 1789224:BFG52_RS08875
uniprot id: A0A1B2LZS4
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1789224:BFG52 RS13365
gene id: 1789224:BFG52_RS13365
uniprot id: A0A1B2M273
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1789224:BFG52 RS09375
gene id: 1789224:BFG52_RS09375
uniprot id: A0A1B2M043
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1789224:BFG52 RS02685
gene id: 1789224:BFG52_RS02685
uniprot id: A0A1B2LWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1789224:BFG52 RS04355
gene id: 1789224:BFG52_RS04355
uniprot id: A0A1B2LXI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1789224:BFG52 RS12070
gene id: 1789224:BFG52_RS12070
uniprot id: A0A1B2M1W1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS06690
gene id: 1789224:BFG52_RS06690
uniprot id: A0A1B2LYN5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1789224:BFG52 RS12075
gene id: 1789224:BFG52_RS12075
uniprot id: A0A1B2M1E1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1789224:BFG52 RS04705
gene id: 1789224:BFG52_RS04705
uniprot id: A0A1B2LXR3
names: Similarity
messages: Belongs to the universal stress protein A family.

1789224:BFG52 RS09350
gene id: 1789224:BFG52_RS09350
uniprot id: A0A1B2M010
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1789224:BFG52 RS03335
gene id: 1789224:BFG52_RS03335
uniprot id: A0A1B2LX11
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1789224:BFG52 RS11585
gene id: 1789224:BFG52_RS11585
uniprot id: A0A1B2M186
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS01080
gene id: 1789224:BFG52_RS01080
uniprot id: A0A1B2LVY1
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1789224:BFG52 RS04490
gene id: 1789224:BFG52_RS04490
uniprot id: A0A1B2LXN6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1789224:BFG52 RS10730
gene id: 1789224:BFG52_RS10730
uniprot id: A0A1B2M0Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1789224:BFG52 RS10000
gene id: 1789224:BFG52_RS10000
uniprot id: A0A1B2M0G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1789224:BFG52 RS01115
gene id: 1789224:BFG52_RS01115
uniprot id: A0A1B2LVX9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1789224:BFG52 RS14955
gene id: 1789224:BFG52_RS14955
uniprot id: A0A1B2M2V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1789224:BFG52 RS09400
gene id: 1789224:BFG52_RS09400
uniprot id: A0A1B2M018
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1789224:BFG52 RS14325
gene id: 1789224:BFG52_RS14325
uniprot id: A0A1B2M2K1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1789224:BFG52 RS03065
gene id: 1789224:BFG52_RS03065
uniprot id: A0A1B2LXD5
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1789224:BFG52 RS06600
gene id: 1789224:BFG52_RS06600
uniprot id: A0A1B2M3X8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1789224:BFG52 RS01365
gene id: 1789224:BFG52_RS01365
uniprot id: A0A1B2LVZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1789224:BFG52 RS05185
gene id: 1789224:BFG52_RS05185
uniprot id: A0A1B2LXY3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1789224:BFG52 RS16125
gene id: 1789224:BFG52_RS16125
uniprot id: A0A1B2M3G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

1789224:BFG52 RS12145
gene id: 1789224:BFG52_RS12145
uniprot id: A0A1B2M1F3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1789224:BFG52 RS08310
gene id: 1789224:BFG52_RS08310
uniprot id: A0A1B2LZJ0
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1789224:BFG52 RS08885
gene id: 1789224:BFG52_RS08885
uniprot id: A0A1B2LZT1
names: Similarity
messages: Belongs to the asparaginase 1 family.

1789224:BFG52 RS05495
gene id: 1789224:BFG52_RS05495
uniprot id: A0A1B2LY46
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1789224:BFG52 RS00030
gene id: 1789224:BFG52_RS00030
uniprot id: A0A1B2LVG0
names: Similarity
messages: Belongs to the DinB family.

1789224:BFG52 RS10615
gene id: 1789224:BFG52_RS10615
uniprot id: A0A1B2M0Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS02270
gene id: 1789224:BFG52_RS02270
uniprot id: A0A1B2LWH1
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1789224:BFG52 RS05040
gene id: 1789224:BFG52_RS05040
uniprot id: A0A1B2LXW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1789224:BFG52 RS00610
gene id: 1789224:BFG52_RS00610
uniprot id: A0A1B2LVR6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1789224:BFG52 RS10050
gene id: 1789224:BFG52_RS10050
uniprot id: A0A1B2M0H5
names: Similarity
messages: Belongs to the citrate synthase family.

1789224:BFG52 RS02430
gene id: 1789224:BFG52_RS02430
uniprot id: A0A1B2LX23
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS02185
gene id: 1789224:BFG52_RS02185
uniprot id: A0A1B2LWF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1789224:BFG52 RS12065
gene id: 1789224:BFG52_RS12065
uniprot id: A0A1B2M1E2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS04845
gene id: 1789224:BFG52_RS04845
uniprot id: A0A1B2LXZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS14410
gene id: 1789224:BFG52_RS14410
uniprot id: A0A1B2M2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1789224:BFG52 RS12410
gene id: 1789224:BFG52_RS12410
uniprot id: A0A1B2M460
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS15940
gene id: 1789224:BFG52_RS15940
uniprot id: A0A1B2M3S5
names: Similarity
messages: Belongs to the UPF0053 family.

1789224:BFG52 RS10955
gene id: 1789224:BFG52_RS10955
uniprot id: A0A1B2M0T1
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS05600
gene id: 1789224:BFG52_RS05600
uniprot id: A0A1B2LY53
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS06970
gene id: 1789224:BFG52_RS06970
uniprot id: A0A1B2LYZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1789224:BFG52 RS00980
gene id: 1789224:BFG52_RS00980
uniprot id: A0A1B2LVW8
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1789224:BFG52 RS01385
gene id: 1789224:BFG52_RS01385
uniprot id: A0A1B2LWJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS06190
gene id: 1789224:BFG52_RS06190
uniprot id: A0A1B2LYE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1789224:BFG52 RS06080
gene id: 1789224:BFG52_RS06080
uniprot id: A0A1B2LYD0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1789224:BFG52 RS09835
gene id: 1789224:BFG52_RS09835
uniprot id: A0A1B2M0A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS09150
gene id: 1789224:BFG52_RS09150
uniprot id: A0A1B2LZY6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1789224:BFG52 RS11995
gene id: 1789224:BFG52_RS11995
uniprot id: A0A1B2M1C6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS04230
gene id: 1789224:BFG52_RS04230
uniprot id: A0A1B2LXI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1789224:BFG52 RS09430
gene id: 1789224:BFG52_RS09430
uniprot id: A0A1B2M040
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1789224:BFG52 RS14895
gene id: 1789224:BFG52_RS14895
uniprot id: A0A1B2M2T5
names: Similarity
messages: Belongs to the DprA/Smf family.

1789224:BFG52 RS04155
gene id: 1789224:BFG52_RS04155
uniprot id: A0A1B2LXG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1789224:BFG52 RS10360
gene id: 1789224:BFG52_RS10360
uniprot id: A0A1B2M0L6
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

1789224:BFG52 RS15040
gene id: 1789224:BFG52_RS15040
uniprot id: A0A1B2M3D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1789224:BFG52 RS14635
gene id: 1789224:BFG52_RS14635
uniprot id: A0A1B2M2P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1789224:BFG52 RS13155
gene id: 1789224:BFG52_RS13155
uniprot id: A0A1B2M1Y8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1789224:BFG52 RS06300
gene id: 1789224:BFG52_RS06300
uniprot id: A0A1B2LYN8
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1789224:BFG52 RS01685
gene id: 1789224:BFG52_RS01685
uniprot id: A0A1B2LW59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS12560
gene id: 1789224:BFG52_RS12560
uniprot id: A0A1B2M1N8
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1789224:BFG52 RS15710
gene id: 1789224:BFG52_RS15710
uniprot id: A0A1B2M375
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1789224:BFG52 RS07015
gene id: 1789224:BFG52_RS07015
uniprot id: A0A1B2LYU6
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1789224:BFG52 RS12250
gene id: 1789224:BFG52_RS12250
uniprot id: A0A1B2M1H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1789224:BFG52 RS00005
gene id: 1789224:BFG52_RS00005
uniprot id: A0A1B2LVF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1789224:BFG52 RS02595
gene id: 1789224:BFG52_RS02595
uniprot id: A0A1B2LWQ0
names: Similarity
messages: Belongs to the VgrG protein family.

1789224:BFG52 RS02630
gene id: 1789224:BFG52_RS02630
uniprot id: A0A1B2LWP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

1789224:BFG52 RS01040
gene id: 1789224:BFG52_RS01040
uniprot id: A0A1B2LVU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1789224:BFG52 RS01670
gene id: 1789224:BFG52_RS01670
uniprot id: A0A1B2M451
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1789224:BFG52 RS10310
gene id: 1789224:BFG52_RS10310
uniprot id: A0A1B2M0H9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1789224:BFG52 RS10235
gene id: 1789224:BFG52_RS10235
uniprot id: A0A1B2M0J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1789224:BFG52 RS09865
gene id: 1789224:BFG52_RS09865
uniprot id: A0A1B2M099
names: Similarity
messages: Belongs to the peptidase M16 family.

1789224:BFG52 RS05505
gene id: 1789224:BFG52_RS05505
uniprot id: A0A1B2LY24
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1789224:BFG52 RS03620
gene id: 1789224:BFG52_RS03620
uniprot id: A0A1B2LX68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS10025
gene id: 1789224:BFG52_RS10025
uniprot id: A0A1B2M0C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1789224:BFG52 RS02730
gene id: 1789224:BFG52_RS02730
uniprot id: A0A1B2LWQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1789224:BFG52 RS04975
gene id: 1789224:BFG52_RS04975
uniprot id: A0A1B2LXS5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1789224:BFG52 RS11840
gene id: 1789224:BFG52_RS11840
uniprot id: A0A1B2M195
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1789224:BFG52 RS12105
gene id: 1789224:BFG52_RS12105
uniprot id: A0A1B2M1E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS02750
gene id: 1789224:BFG52_RS02750
uniprot id: A0A1B2LWS1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1789224:BFG52 RS04540
gene id: 1789224:BFG52_RS04540
uniprot id: A0A1B2LXL8
names: Similarity
messages: Belongs to the transposase 8 family.

1789224:BFG52 RS04360
gene id: 1789224:BFG52_RS04360
uniprot id: A0A1B2LXL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1789224:BFG52 RS05820
gene id: 1789224:BFG52_RS05820
uniprot id: A0A1B2LY93
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1789224:BFG52 RS05590
gene id: 1789224:BFG52_RS05590
uniprot id: A0A1B2M3X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1789224:BFG52 RS02330
gene id: 1789224:BFG52_RS02330
uniprot id: A0A1B2LWI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS16285
gene id: 1789224:BFG52_RS16285
uniprot id: A0A1B2M3J0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1789224:BFG52 RS08675
gene id: 1789224:BFG52_RS08675
uniprot id: A0A1B2LZP5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1789224:BFG52 RS10820
gene id: 1789224:BFG52_RS10820
uniprot id: A0A1B2M0R3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1789224:BFG52 RS04805
gene id: 1789224:BFG52_RS04805
uniprot id: A0A1B2LXP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1789224:BFG52 RS01480
gene id: 1789224:BFG52_RS01480
uniprot id: A0A1B2LW25
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1789224:BFG52 RS16435
gene id: 1789224:BFG52_RS16435
uniprot id: A0A1B2M3L1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS12275
gene id: 1789224:BFG52_RS12275
uniprot id: A0A1B2M4A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS12700
gene id: 1789224:BFG52_RS12700
uniprot id: A0A1B2M1Q3
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS04600
gene id: 1789224:BFG52_RS04600
uniprot id: A0A1B2M404
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS02380
gene id: 1789224:BFG52_RS02380
uniprot id: A0A1B2LWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1789224:BFG52 RS05930
gene id: 1789224:BFG52_RS05930
uniprot id: A0A1B2LYB3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1789224:BFG52 RS16510
gene id: 1789224:BFG52_RS16510
uniprot id: A0A1B2M3R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1789224:BFG52 RS01615
gene id: 1789224:BFG52_RS01615
uniprot id: A0A1B2LW65
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1789224:BFG52 RS01230
gene id: 1789224:BFG52_RS01230
uniprot id: A0A1B2LVZ3
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS14585
gene id: 1789224:BFG52_RS14585
uniprot id: A0A1B2M2N5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1789224:BFG52 RS01815
gene id: 1789224:BFG52_RS01815
uniprot id: A0A1B2LWR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

1789224:BFG52 RS02020
gene id: 1789224:BFG52_RS02020
uniprot id: A0A1B2LWC0
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS00550
gene id: 1789224:BFG52_RS00550
uniprot id: A0A1B2LW44
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1789224:BFG52 RS14055
gene id: 1789224:BFG52_RS14055
uniprot id: A0A1B2M2H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS05855
gene id: 1789224:BFG52_RS05855
uniprot id: A0A1B2LYA5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS11990
gene id: 1789224:BFG52_RS11990
uniprot id: A0A1B2M1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1789224:BFG52 RS06640
gene id: 1789224:BFG52_RS06640
uniprot id: A0A1B2LYM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1789224:BFG52 RS00015
gene id: 1789224:BFG52_RS00015
uniprot id: A0A1B2LVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1789224:BFG52 RS05895
gene id: 1789224:BFG52_RS05895
uniprot id: A0A1B2LYA6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1789224:BFG52 RS13070
gene id: 1789224:BFG52_RS13070
uniprot id: A0A1B2M2E6
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS14560
gene id: 1789224:BFG52_RS14560
uniprot id: A0A1B2M2M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1789224:BFG52 RS11610
gene id: 1789224:BFG52_RS11610
uniprot id: A0A1B2M159
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1789224:BFG52 RS11830
gene id: 1789224:BFG52_RS11830
uniprot id: A0A1B2M1A0
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS16330
gene id: 1789224:BFG52_RS16330
uniprot id: A0A1B2M3M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1789224:BFG52 RS16080
gene id: 1789224:BFG52_RS16080
uniprot id: A0A1B2M3D6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1789224:BFG52 RS13835
gene id: 1789224:BFG52_RS13835
uniprot id: A0A1B2M2A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1789224:BFG52 RS00330
gene id: 1789224:BFG52_RS00330
uniprot id: A0A1B2M3Q1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1789224:BFG52 RS15995
gene id: 1789224:BFG52_RS15995
uniprot id: A0A1B2M3I6
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS14645
gene id: 1789224:BFG52_RS14645
uniprot id: A0A1B2M2Q2
names: Similarity
messages: Belongs to the RutC family.

1789224:BFG52 RS03165
gene id: 1789224:BFG52_RS03165
uniprot id: A0A1B2LWY1
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS08235
gene id: 1789224:BFG52_RS08235
uniprot id: A0A1B2LZH6
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1789224:BFG52 RS06595
gene id: 1789224:BFG52_RS06595
uniprot id: A0A1B2LYL5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS07205
gene id: 1789224:BFG52_RS07205
uniprot id: A0A1B2LZF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1789224:BFG52 RS06535
gene id: 1789224:BFG52_RS06535
uniprot id: A0A1B2LYM1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1789224:BFG52 RS02165
gene id: 1789224:BFG52_RS02165
uniprot id: A0A1B2LWF6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1789224:BFG52 RS04985
gene id: 1789224:BFG52_RS04985
uniprot id: A0A1B2LXV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1789224:BFG52 RS15095
gene id: 1789224:BFG52_RS15095
uniprot id: A0A1B2M2Y3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1789224:BFG52 RS09360
gene id: 1789224:BFG52_RS09360
uniprot id: A0A1B2M017
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS13675
gene id: 1789224:BFG52_RS13675
uniprot id: A0A1B2M276
names: Similarity
messages: Belongs to the YfgM family.

1789224:BFG52 RS03535
gene id: 1789224:BFG52_RS03535
uniprot id: A0A1B2M3S1
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1789224:BFG52 RS13075
gene id: 1789224:BFG52_RS13075
uniprot id: A0A1B2M1X3
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS01935
gene id: 1789224:BFG52_RS01935
uniprot id: A0A1B2LWC2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1789224:BFG52 RS02415
gene id: 1789224:BFG52_RS02415
uniprot id: A0A1B2LWK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1789224:BFG52 RS14315
gene id: 1789224:BFG52_RS14315
uniprot id: A0A1B2M2J2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1789224:BFG52 RS02015
gene id: 1789224:BFG52_RS02015
uniprot id: A0A1B2LWH9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1789224:BFG52 RS07155
gene id: 1789224:BFG52_RS07155
uniprot id: A0A1B2LYY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1789224:BFG52 RS10480
gene id: 1789224:BFG52_RS10480
uniprot id: A0A1B2M0K5
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS05295
gene id: 1789224:BFG52_RS05295
uniprot id: A0A1B2LXZ9
names: Similarity
messages: Belongs to the fabD family.

1789224:BFG52 RS09075
gene id: 1789224:BFG52_RS09075
uniprot id: A0A1B2LZX2
names: Subcellular Location Annotation
messages: Cytoplasm

1789224:BFG52 RS04205
gene id: 1789224:BFG52_RS04205
uniprot id: A0A1B2LXI0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1789224:BFG52 RS15900
gene id: 1789224:BFG52_RS15900
uniprot id: A0A1B2M3A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1789224:BFG52 RS02130
gene id: 1789224:BFG52_RS02130
uniprot id: A0A1B2LWF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1789224:BFG52 RS08275
gene id: 1789224:BFG52_RS08275
uniprot id: A0A1B2LZL9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1789224:BFG52 RS01590
gene id: 1789224:BFG52_RS01590
uniprot id: A0A1B2LW47
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1789224:BFG52 RS06870
gene id: 1789224:BFG52_RS06870
uniprot id: A0A1B2M429
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1789224:BFG52 RS02955
gene id: 1789224:BFG52_RS02955
uniprot id: A0A1B2M470
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS09845
gene id: 1789224:BFG52_RS09845
uniprot id: A0A1B2M424
names: Similarity
messages: Belongs to the UPF0319 family.

1789224:BFG52 RS05585
gene id: 1789224:BFG52_RS05585
uniprot id: A0A1B2LY72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1789224:BFG52 RS13240
gene id: 1789224:BFG52_RS13240
uniprot id: A0A1B2M207
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1789224:BFG52 RS12295
gene id: 1789224:BFG52_RS12295
uniprot id: A0A1B2M1I2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1789224:BFG52 RS00485
gene id: 1789224:BFG52_RS00485
uniprot id: A0A1B2LVK8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1789224:BFG52 RS02795
gene id: 1789224:BFG52_RS02795
uniprot id: A0A1B2LX89
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1789224:BFG52 RS00195
gene id: 1789224:BFG52_RS00195
uniprot id: A0A1B2LVG8
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS00495
gene id: 1789224:BFG52_RS00495
uniprot id: A0A1B2LW42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1789224:BFG52 RS10080
gene id: 1789224:BFG52_RS10080
uniprot id: A0A1B2M466
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1789224:BFG52 RS10110
gene id: 1789224:BFG52_RS10110
uniprot id: A0A1B2M0F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1789224:BFG52 RS12950
gene id: 1789224:BFG52_RS12950
uniprot id: A0A1B2M1U8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1789224:BFG52 RS13905
gene id: 1789224:BFG52_RS13905
uniprot id: A0A1B2M2G2
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS15510
gene id: 1789224:BFG52_RS15510
uniprot id: A0A1B2M3K9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1789224:BFG52 RS14065
gene id: 1789224:BFG52_RS14065
uniprot id: A0A1B2M2K2
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS11265
gene id: 1789224:BFG52_RS11265
uniprot id: A0A1B2M0Z6
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS01840
gene id: 1789224:BFG52_RS01840
uniprot id: A0A1B2M3P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1789224:BFG52 RS15550
gene id: 1789224:BFG52_RS15550
uniprot id: A0A1B2M3B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1789224:BFG52 RS00620
gene id: 1789224:BFG52_RS00620
uniprot id: A0A1B2M3Q4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1789224:BFG52 RS04285
gene id: 1789224:BFG52_RS04285
uniprot id: A0A1B2LXJ2
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1789224:BFG52 RS12045
gene id: 1789224:BFG52_RS12045
uniprot id: A0A1B2M1G2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1789224:BFG52 RS08720
gene id: 1789224:BFG52_RS08720
uniprot id: A0A1B2LZU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1789224:BFG52 RS10655
gene id: 1789224:BFG52_RS10655
uniprot id: A0A1B2M0N9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1789224:BFG52 RS05315
gene id: 1789224:BFG52_RS05315
uniprot id: A0A1B2LY06
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS09435
gene id: 1789224:BFG52_RS09435
uniprot id: A0A1B2M061
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1789224:BFG52 RS05050
gene id: 1789224:BFG52_RS05050
uniprot id: A0A1B2LXT6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1789224:BFG52 RS10440
gene id: 1789224:BFG52_RS10440
uniprot id: A0A1B2M0M1
names: Similarity
messages: Belongs to the UPF0246 family.

1789224:BFG52 RS15115
gene id: 1789224:BFG52_RS15115
uniprot id: A0A1B2M3E9
names: Similarity
messages: Belongs to the GSP N family.

1789224:BFG52 RS01415
gene id: 1789224:BFG52_RS01415
uniprot id: A0A1B2LW69
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1789224:BFG52 RS04440
gene id: 1789224:BFG52_RS04440
uniprot id: A0A1B2LXM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1789224:BFG52 RS14145
gene id: 1789224:BFG52_RS14145
uniprot id: A0A1B2M2X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS05525
gene id: 1789224:BFG52_RS05525
uniprot id: A0A1B2M3V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

1789224:BFG52 RS01520
gene id: 1789224:BFG52_RS01520
uniprot id: A0A1B2LW28
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1789224:BFG52 RS00605
gene id: 1789224:BFG52_RS00605
uniprot id: A0A1B2LW58
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1789224:BFG52 RS03965
gene id: 1789224:BFG52_RS03965
uniprot id: A0A1B2LXC2
names: Similarity
messages: Belongs to the XseB family.

1789224:BFG52 RS08380
gene id: 1789224:BFG52_RS08380
uniprot id: A0A1B2LZL4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1789224:BFG52 RS03440
gene id: 1789224:BFG52_RS03440
uniprot id: A0A1B2LX85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1789224:BFG52 RS12850
gene id: 1789224:BFG52_RS12850
uniprot id: A0A1B2M1X0
names: Similarity
messages: Belongs to the GppA/Ppx family.

1789224:BFG52 RS05015
gene id: 1789224:BFG52_RS05015
uniprot id: A0A1B2LXW3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1789224:BFG52 RS01325
gene id: 1789224:BFG52_RS01325
uniprot id: A0A1B2LWI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1789224:BFG52 RS00280
gene id: 1789224:BFG52_RS00280
uniprot id: A0A1B2LVJ6
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS14150
gene id: 1789224:BFG52_RS14150
uniprot id: A0A1B2M2H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS00745
gene id: 1789224:BFG52_RS00745
uniprot id: A0A1B2LVS0
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS11730
gene id: 1789224:BFG52_RS11730
uniprot id: A0A1B2M174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS01465
gene id: 1789224:BFG52_RS01465
uniprot id: A0A1B2LW81
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1789224:BFG52 RS12740
gene id: 1789224:BFG52_RS12740
uniprot id: A0A1B2M1R5
names: Similarity
messages: Belongs to the thioredoxin family.

1789224:BFG52 RS14550
gene id: 1789224:BFG52_RS14550
uniprot id: A0A1B2M2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1789224:BFG52 RS09140
gene id: 1789224:BFG52_RS09140
uniprot id: A0A1B2LZY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1789224:BFG52 RS13270
gene id: 1789224:BFG52_RS13270
uniprot id: A0A1B2M2I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1789224:BFG52 RS04180
gene id: 1789224:BFG52_RS04180
uniprot id: A0A1B2LXG8
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1789224:BFG52 RS16325
gene id: 1789224:BFG52_RS16325
uniprot id: A0A1B2M4C1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1789224:BFG52 RS04810
gene id: 1789224:BFG52_RS04810
uniprot id: A0A1B2LY94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1789224:BFG52 RS09090
gene id: 1789224:BFG52_RS09090
uniprot id: A0A1B2LZW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1789224:BFG52 RS14500
gene id: 1789224:BFG52_RS14500
uniprot id: A0A1B2M2L3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS05455
gene id: 1789224:BFG52_RS05455
uniprot id: A0A1B2LY32
names: Similarity
messages: Belongs to the TelA family.

1789224:BFG52 RS00955
gene id: 1789224:BFG52_RS00955
uniprot id: A0A1B2LVW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS06125
gene id: 1789224:BFG52_RS06125
uniprot id: A0A1B2LYG2
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1789224:BFG52 RS13515
gene id: 1789224:BFG52_RS13515
uniprot id: A0A1B2M246
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1789224:BFG52 RS05910
gene id: 1789224:BFG52_RS05910
uniprot id: A0A1B2LYB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

1789224:BFG52 RS13545
gene id: 1789224:BFG52_RS13545
uniprot id: A0A1B2M251
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1789224:BFG52 RS02200
gene id: 1789224:BFG52_RS02200
uniprot id: A0A1B2LWH7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1789224:BFG52 RS04150
gene id: 1789224:BFG52_RS04150
uniprot id: A0A1B2LXH0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1789224:BFG52 RS12470
gene id: 1789224:BFG52_RS12470
uniprot id: A0A1B2M1L8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1789224:BFG52 RS09365
gene id: 1789224:BFG52_RS09365
uniprot id: A0A1B2M021
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS03045
gene id: 1789224:BFG52_RS03045
uniprot id: A0A1B2LX16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

1789224:BFG52 RS01180
gene id: 1789224:BFG52_RS01180
uniprot id: A0A1B2LVY4
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS00940
gene id: 1789224:BFG52_RS00940
uniprot id: A0A1B2LVU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1789224:BFG52 RS12185
gene id: 1789224:BFG52_RS12185
uniprot id: A0A1B2M1K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1789224:BFG52 RS12260
gene id: 1789224:BFG52_RS12260
uniprot id: A0A1B2M1G8
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1789224:BFG52 RS16400
gene id: 1789224:BFG52_RS16400
uniprot id: A0A1B2M402
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1789224:BFG52 RS14200
gene id: 1789224:BFG52_RS14200
uniprot id: A0A1B2M2H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1789224:BFG52 RS13055
gene id: 1789224:BFG52_RS13055
uniprot id: A0A1B2M1W9
names: Similarity
messages: Belongs to the peptidase S66 family.

1789224:BFG52 RS01205
gene id: 1789224:BFG52_RS01205
uniprot id: A0A1B2LVX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1789224:BFG52 RS01060
gene id: 1789224:BFG52_RS01060
uniprot id: A0A1B2LVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1789224:BFG52 RS12240
gene id: 1789224:BFG52_RS12240
uniprot id: A0A1B2M1H5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1789224:BFG52 RS01880
gene id: 1789224:BFG52_RS01880
uniprot id: A0A1B2M3N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1789224:BFG52 RS12465
gene id: 1789224:BFG52_RS12465
uniprot id: A0A1B2M234
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS10860
gene id: 1789224:BFG52_RS10860
uniprot id: A0A1B2M0U4
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1789224:BFG52 RS12200
gene id: 1789224:BFG52_RS12200
uniprot id: A0A1B2M1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1789224:BFG52 RS09065
gene id: 1789224:BFG52_RS09065
uniprot id: A0A1B2LZX0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1789224:BFG52 RS06400
gene id: 1789224:BFG52_RS06400
uniprot id: A0A1B2LYI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1789224:BFG52 RS06695
gene id: 1789224:BFG52_RS06695
uniprot id: A0A1B2LYV0
names: Similarity
messages: Belongs to the peptidase S11 family.

1789224:BFG52 RS02070
gene id: 1789224:BFG52_RS02070
uniprot id: A0A1B2LWJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1789224:BFG52 RS13915
gene id: 1789224:BFG52_RS13915
uniprot id: A0A1B2M2T9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1789224:BFG52 RS03410
gene id: 1789224:BFG52_RS03410
uniprot id: A0A1B2LXJ9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1789224:BFG52 RS12610
gene id: 1789224:BFG52_RS12610
uniprot id: A0A1B2M1T0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1789224:BFG52 RS15415
gene id: 1789224:BFG52_RS15415
uniprot id: A0A1B2M328
names: Subcellular Location Annotation
messages: Cytoplasm

1789224:BFG52 RS16520
gene id: 1789224:BFG52_RS16520
uniprot id: A0A1B2M3N9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1789224:BFG52 RS13250
gene id: 1789224:BFG52_RS13250
uniprot id: A0A1B2M232
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1789224:BFG52 RS08585
gene id: 1789224:BFG52_RS08585
uniprot id: A0A1B2LZN5
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS05435
gene id: 1789224:BFG52_RS05435
uniprot id: A0A1B2LY33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1789224:BFG52 RS08520
gene id: 1789224:BFG52_RS08520
uniprot id: A0A1B2LZQ8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

1789224:BFG52 RS12080
gene id: 1789224:BFG52_RS12080
uniprot id: A0A1B2M1F5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1789224:BFG52 RS06840
gene id: 1789224:BFG52_RS06840
uniprot id: A0A1B2LYS7
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1789224:BFG52 RS05195
gene id: 1789224:BFG52_RS05195
uniprot id: A0A1B2LXZ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1789224:BFG52 RS09725
gene id: 1789224:BFG52_RS09725
uniprot id: A0A1B2M0Q9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS15505
gene id: 1789224:BFG52_RS15505
uniprot id: A0A1B2M348
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1789224:BFG52 RS03080
gene id: 1789224:BFG52_RS03080
uniprot id: A0A1B2LWX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS12040
gene id: 1789224:BFG52_RS12040
uniprot id: A0A1B2M1E4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1789224:BFG52 RS10305
gene id: 1789224:BFG52_RS10305
uniprot id: A0A1B2M0H6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1789224:BFG52 RS12120
gene id: 1789224:BFG52_RS12120
uniprot id: A0A1B2M1X2
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS00835
gene id: 1789224:BFG52_RS00835
uniprot id: A0A1B2LVR5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS02150
gene id: 1789224:BFG52_RS02150
uniprot id: A0A1B2LWG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1789224:BFG52 RS01460
gene id: 1789224:BFG52_RS01460
uniprot id: A0A1B2LW18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1789224:BFG52 RS06845
gene id: 1789224:BFG52_RS06845
uniprot id: A0A1B2LYR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1789224:BFG52 RS02095
gene id: 1789224:BFG52_RS02095
uniprot id: A0A1B2LWF9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1789224:BFG52 RS16315
gene id: 1789224:BFG52_RS16315
uniprot id: A0A1B2M3I4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1789224:BFG52 RS01050
gene id: 1789224:BFG52_RS01050
uniprot id: A0A1B2LVX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1789224:BFG52 RS05680
gene id: 1789224:BFG52_RS05680
uniprot id: A0A1B2LY76
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1789224:BFG52 RS12050
gene id: 1789224:BFG52_RS12050
uniprot id: A0A1B2M1D7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS12290
gene id: 1789224:BFG52_RS12290
uniprot id: A0A1B2M1M1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS16055
gene id: 1789224:BFG52_RS16055
uniprot id: A0A1B2M3D2
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1789224:BFG52 RS04715
gene id: 1789224:BFG52_RS04715
uniprot id: A0A1B2LXQ1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS13840
gene id: 1789224:BFG52_RS13840
uniprot id: A0A1B2M2F2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS13805
gene id: 1789224:BFG52_RS13805
uniprot id: A0A1B2M2A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1789224:BFG52 RS13045
gene id: 1789224:BFG52_RS13045
uniprot id: A0A1B2M1X7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1789224:BFG52 RS16515
gene id: 1789224:BFG52_RS16515
uniprot id: A0A1B2M421
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1789224:BFG52 RS10175
gene id: 1789224:BFG52_RS10175
uniprot id: A0A1B2M0Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1789224:BFG52 RS03435
gene id: 1789224:BFG52_RS03435
uniprot id: A0A1B2LX28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

1789224:BFG52 RS06260
gene id: 1789224:BFG52_RS06260
uniprot id: A0A1B2LYI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1789224:BFG52 RS07120
gene id: 1789224:BFG52_RS07120
uniprot id: A0A1B2LYY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1789224:BFG52 RS09285
gene id: 1789224:BFG52_RS09285
uniprot id: A0A1B2M032
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS08325
gene id: 1789224:BFG52_RS08325
uniprot id: A0A1B2LZH5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1789224:BFG52 RS14605
gene id: 1789224:BFG52_RS14605
uniprot id: A0A1B2M2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1789224:BFG52 RS03180
gene id: 1789224:BFG52_RS03180
uniprot id: A0A1B2LXF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1789224:BFG52 RS09530
gene id: 1789224:BFG52_RS09530
uniprot id: A0A1B2M073
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1789224:BFG52 RS11835
gene id: 1789224:BFG52_RS11835
uniprot id: A0A1B2M1E0
names: Similarity
messages: Belongs to the peptidase S16 family.

1789224:BFG52 RS03030
gene id: 1789224:BFG52_RS03030
uniprot id: A0A1B2LWW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS00145
gene id: 1789224:BFG52_RS00145
uniprot id: A0A1B2LVF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1789224:BFG52 RS13280
gene id: 1789224:BFG52_RS13280
uniprot id: A0A1B2M210
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1789224:BFG52 RS09320
gene id: 1789224:BFG52_RS09320
uniprot id: A0A1B2M020
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS15270
gene id: 1789224:BFG52_RS15270
uniprot id: A0A1B2M2Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1789224:BFG52 RS12880
gene id: 1789224:BFG52_RS12880
uniprot id: A0A1B2M1T6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1789224:BFG52 RS15925
gene id: 1789224:BFG52_RS15925
uniprot id: A0A1B2M3B2
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS06160
gene id: 1789224:BFG52_RS06160
uniprot id: A0A1B2LYW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1789224:BFG52 RS05560
gene id: 1789224:BFG52_RS05560
uniprot id: A0A1B2LY55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1789224:BFG52 RS10010
gene id: 1789224:BFG52_RS10010
uniprot id: A0A1B2M0V9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS04990
gene id: 1789224:BFG52_RS04990
uniprot id: A0A1B2LXX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1789224:BFG52 RS01085
gene id: 1789224:BFG52_RS01085
uniprot id: A0A1B2LVW1
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS14235
gene id: 1789224:BFG52_RS14235
uniprot id: A0A1B2M2Y8
names: Similarity
messages: Belongs to the PhoH family.

1789224:BFG52 RS11880
gene id: 1789224:BFG52_RS11880
uniprot id: A0A1B2M1A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS15595
gene id: 1789224:BFG52_RS15595
uniprot id: A0A1B2M347
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS13320
gene id: 1789224:BFG52_RS13320
uniprot id: A0A1B2M2J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1789224:BFG52 RS06210
gene id: 1789224:BFG52_RS06210
uniprot id: A0A1B2LYH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1789224:BFG52 RS04115
gene id: 1789224:BFG52_RS04115
uniprot id: A0A1B2LXK6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1789224:BFG52 RS00985
gene id: 1789224:BFG52_RS00985
uniprot id: A0A1B2LVW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1789224:BFG52 RS13740
gene id: 1789224:BFG52_RS13740
uniprot id: A0A1B2M298
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1789224:BFG52 RS04300
gene id: 1789224:BFG52_RS04300
uniprot id: A0A1B2LY07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS01005
gene id: 1789224:BFG52_RS01005
uniprot id: A0A1B2LVX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS05230
gene id: 1789224:BFG52_RS05230
uniprot id: A0A1B2LXW6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1789224:BFG52 RS03495
gene id: 1789224:BFG52_RS03495
uniprot id: A0A1B2LX35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1789224:BFG52 RS10180
gene id: 1789224:BFG52_RS10180
uniprot id: A0A1B2M0E9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1789224:BFG52 RS04940
gene id: 1789224:BFG52_RS04940
uniprot id: A0A1B2LXU6
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1789224:BFG52 RS04140
gene id: 1789224:BFG52_RS04140
uniprot id: A0A1B2LXX9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1789224:BFG52 RS01715
gene id: 1789224:BFG52_RS01715
uniprot id: A0A1B2LWP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1789224:BFG52 RS02100
gene id: 1789224:BFG52_RS02100
uniprot id: A0A1B2LWF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1789224:BFG52 RS09385
gene id: 1789224:BFG52_RS09385
uniprot id: A0A1B2M052
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS15615
gene id: 1789224:BFG52_RS15615
uniprot id: A0A1B2M3N1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS12245
gene id: 1789224:BFG52_RS12245
uniprot id: A0A1B2M1Z1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1789224:BFG52 RS06860
gene id: 1789224:BFG52_RS06860
uniprot id: A0A1B2LYT5
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS05410
gene id: 1789224:BFG52_RS05410
uniprot id: A0A1B2LY40
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS13355
gene id: 1789224:BFG52_RS13355
uniprot id: A0A1B2M252
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS10005
gene id: 1789224:BFG52_RS10005
uniprot id: A0A1B2M0D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1789224:BFG52 RS11590
gene id: 1789224:BFG52_RS11590
uniprot id: A0A1B2M162
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1789224:BFG52 RS15610
gene id: 1789224:BFG52_RS15610
uniprot id: A0A1B2M4H1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1789224:BFG52 RS15775
gene id: 1789224:BFG52_RS15775
uniprot id: A0A1B2M3P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1789224:BFG52 RS03290
gene id: 1789224:BFG52_RS03290
uniprot id: A0A1B2LX03
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1789224:BFG52 RS15930
gene id: 1789224:BFG52_RS15930
uniprot id: A0A1B2M3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1789224:BFG52 RS13550
gene id: 1789224:BFG52_RS13550
uniprot id: A0A1B2M259
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1789224:BFG52 RS14625
gene id: 1789224:BFG52_RS14625
uniprot id: A0A1B2M2N3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1789224:BFG52 RS05170
gene id: 1789224:BFG52_RS05170
uniprot id: A0A1B2LXY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1789224:BFG52 RS07745
gene id: 1789224:BFG52_RS07745
uniprot id: A0A1B2LZA2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1789224:BFG52 RS06170
gene id: 1789224:BFG52_RS06170
uniprot id: A0A1B2LYG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1789224:BFG52 RS04085
gene id: 1789224:BFG52_RS04085
uniprot id: A0A1B2LXE0
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS05660
gene id: 1789224:BFG52_RS05660
uniprot id: A0A1B2LY61
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS14545
gene id: 1789224:BFG52_RS14545
uniprot id: A0A1B2M2N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS12735
gene id: 1789224:BFG52_RS12735
uniprot id: A0A1B2M1R7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1789224:BFG52 RS15835
gene id: 1789224:BFG52_RS15835
uniprot id: A0A1B2M3Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1789224:BFG52 RS09650
gene id: 1789224:BFG52_RS09650
uniprot id: A0A1B2M081
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1789224:BFG52 RS11720
gene id: 1789224:BFG52_RS11720
uniprot id: A0A1B2M177
names: Similarity
messages: Belongs to the peptidase M16 family.

1789224:BFG52 RS11660
gene id: 1789224:BFG52_RS11660
uniprot id: A0A1B2M1P6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1789224:BFG52 RS16180
gene id: 1789224:BFG52_RS16180
uniprot id: A0A1B2M3H1
names: Similarity
messages: Belongs to the DapA family.

1789224:BFG52 RS14400
gene id: 1789224:BFG52_RS14400
uniprot id: A0A1B2M319
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1789224:BFG52 RS11140
gene id: 1789224:BFG52_RS11140
uniprot id: A0A1B2M1G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS00245
gene id: 1789224:BFG52_RS00245
uniprot id: A0A1B2LVG9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS16455
gene id: 1789224:BFG52_RS16455
uniprot id: A0A1B2M3N5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1789224:BFG52 RS11385
gene id: 1789224:BFG52_RS11385
uniprot id: A0A1B2M117
names: Similarity
messages: Belongs to the peptidase M24B family.

1789224:BFG52 RS15580
gene id: 1789224:BFG52_RS15580
uniprot id: A0A1B2M356
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1789224:BFG52 RS11940
gene id: 1789224:BFG52_RS11940
uniprot id: A0A1B2M1B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1789224:BFG52 RS16165
gene id: 1789224:BFG52_RS16165
uniprot id: A0A1B2M3G9
names: Similarity
messages: Belongs to the sulfatase family.

1789224:BFG52 RS04610
gene id: 1789224:BFG52_RS04610
uniprot id: A0A1B2LXN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1789224:BFG52 RS09940
gene id: 1789224:BFG52_RS09940
uniprot id: A0A1B2M0F5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS06075
gene id: 1789224:BFG52_RS06075
uniprot id: A0A1B2LYE7
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS12485
gene id: 1789224:BFG52_RS12485
uniprot id: A0A1B2M1L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1789224:BFG52 RS04950
gene id: 1789224:BFG52_RS04950
uniprot id: A0A1B2LY13
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1789224:BFG52 RS15765
gene id: 1789224:BFG52_RS15765
uniprot id: A0A1B2M3F0
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1789224:BFG52 RS04590
gene id: 1789224:BFG52_RS04590
uniprot id: A0A1B2LXP9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

1789224:BFG52 RS00500
gene id: 1789224:BFG52_RS00500
uniprot id: A0A1B2LVP5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1789224:BFG52 RS03825
gene id: 1789224:BFG52_RS03825
uniprot id: A0A1B2LXA8
names: Subcellular Location Annotation
messages: Virion

1789224:BFG52 RS05420
gene id: 1789224:BFG52_RS05420
uniprot id: A0A1B2LY25
names: Similarity
messages: Belongs to the peptidase S49 family.

1789224:BFG52 RS01015
gene id: 1789224:BFG52_RS01015
uniprot id: A0A1B2LVV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1789224:BFG52 RS05110
gene id: 1789224:BFG52_RS05110
uniprot id: A0A1B2LXX5
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1789224:BFG52 RS12905
gene id: 1789224:BFG52_RS12905
uniprot id: A0A1B2M1Y0
names: Similarity
messages: Belongs to the GST superfamily.

1789224:BFG52 RS02285
gene id: 1789224:BFG52_RS02285
uniprot id: A0A1B2LWN8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS04080
gene id: 1789224:BFG52_RS04080
uniprot id: A0A1B2LXX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1789224:BFG52 RS09745
gene id: 1789224:BFG52_RS09745
uniprot id: A0A1B2M086
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1789224:BFG52 RS11560
gene id: 1789224:BFG52_RS11560
uniprot id: A0A1B2M172
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

1789224:BFG52 RS02700
gene id: 1789224:BFG52_RS02700
uniprot id: A0A1B2LWR2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1789224:BFG52 RS14230
gene id: 1789224:BFG52_RS14230
uniprot id: A0A1B2M2H9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1789224:BFG52 RS00875
gene id: 1789224:BFG52_RS00875
uniprot id: A0A1B2LVT8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS13210
gene id: 1789224:BFG52_RS13210
uniprot id: A0A1B2M243
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1789224:BFG52 RS11925
gene id: 1789224:BFG52_RS11925
uniprot id: A0A1B2M1B3
names: Similarity
messages: Belongs to the peptidase S49 family.

1789224:BFG52 RS09855
gene id: 1789224:BFG52_RS09855
uniprot id: A0A1B2M0C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1789224:BFG52 RS12515
gene id: 1789224:BFG52_RS12515
uniprot id: A0A1B2M245
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1789224:BFG52 RS15870
gene id: 1789224:BFG52_RS15870
uniprot id: A0A1B2M3A0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1789224:BFG52 RS15140
gene id: 1789224:BFG52_RS15140
uniprot id: A0A1B2M2X8
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1789224:BFG52 RS11640
gene id: 1789224:BFG52_RS11640
uniprot id: A0A1B2M199
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1789224:BFG52 RS11305
gene id: 1789224:BFG52_RS11305
uniprot id: A0A1B2M145
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

1789224:BFG52 RS12825
gene id: 1789224:BFG52_RS12825
uniprot id: A0A1B2M1S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1789224:BFG52 RS02515
gene id: 1789224:BFG52_RS02515
uniprot id: A0A1B2LWL7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS15245
gene id: 1789224:BFG52_RS15245
uniprot id: A0A1B2M2Z1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1789224:BFG52 RS03215
gene id: 1789224:BFG52_RS03215
uniprot id: A0A1B2LWY8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS14035
gene id: 1789224:BFG52_RS14035
uniprot id: A0A1B2M2E0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS04640
gene id: 1789224:BFG52_RS04640
uniprot id: A0A1B2LY65
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1789224:BFG52 RS16075
gene id: 1789224:BFG52_RS16075
uniprot id: A0A1B2M3G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1789224:BFG52 RS05215
gene id: 1789224:BFG52_RS05215
uniprot id: A0A1B2LY51
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1789224:BFG52 RS00645
gene id: 1789224:BFG52_RS00645
uniprot id: A0A1B2LVP9
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS10210
gene id: 1789224:BFG52_RS10210
uniprot id: A0A1B2M0H8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1789224:BFG52 RS00455
gene id: 1789224:BFG52_RS00455
uniprot id: A0A1B2LVN2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1789224:BFG52 RS10240
gene id: 1789224:BFG52_RS10240
uniprot id: A0A1B2M0G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1789224:BFG52 RS03095
gene id: 1789224:BFG52_RS03095
uniprot id: A0A1B2LX26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS00040
gene id: 1789224:BFG52_RS00040
uniprot id: A0A1B2LVG2
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS03055
gene id: 1789224:BFG52_RS03055
uniprot id: A0A1B2LWW4
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1789224:BFG52 RS06120
gene id: 1789224:BFG52_RS06120
uniprot id: A0A1B2LYG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS15235
gene id: 1789224:BFG52_RS15235
uniprot id: A0A1B2M310
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1789224:BFG52 RS10220
gene id: 1789224:BFG52_RS10220
uniprot id: A0A1B2M0H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1789224:BFG52 RS14775
gene id: 1789224:BFG52_RS14775
uniprot id: A0A1B2M2Q7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1789224:BFG52 RS04290
gene id: 1789224:BFG52_RS04290
uniprot id: A0A1B2LXI6
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1789224:BFG52 RS14435
gene id: 1789224:BFG52_RS14435
uniprot id: A0A1B2M2K0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1789224:BFG52 RS00965
gene id: 1789224:BFG52_RS00965
uniprot id: A0A1B2LVT0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1789224:BFG52 RS14050
gene id: 1789224:BFG52_RS14050
uniprot id: A0A1B2M2F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS16420
gene id: 1789224:BFG52_RS16420
uniprot id: A0A1B2M3J8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1789224:BFG52 RS01745
gene id: 1789224:BFG52_RS01745
uniprot id: A0A1B2LWD3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1789224:BFG52 RS14310
gene id: 1789224:BFG52_RS14310
uniprot id: A0A1B2M2H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1789224:BFG52 RS09145
gene id: 1789224:BFG52_RS09145
uniprot id: A0A1B2M416
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1789224:BFG52 RS16240
gene id: 1789224:BFG52_RS16240
uniprot id: A0A1B2M3X2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1789224:BFG52 RS14840
gene id: 1789224:BFG52_RS14840
uniprot id: A0A1B2M2U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1789224:BFG52 RS12525
gene id: 1789224:BFG52_RS12525
uniprot id: A0A1B2M1M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS08375
gene id: 1789224:BFG52_RS08375
uniprot id: A0A1B2M462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS10135
gene id: 1789224:BFG52_RS10135
uniprot id: A0A1B2M0F2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1789224:BFG52 RS09920
gene id: 1789224:BFG52_RS09920
uniprot id: A0A1B2M0B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1789224:BFG52 RS13760
gene id: 1789224:BFG52_RS13760
uniprot id: A0A1B2M286
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1789224:BFG52 RS06740
gene id: 1789224:BFG52_RS06740
uniprot id: A0A1B2LYP5
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS08370
gene id: 1789224:BFG52_RS08370
uniprot id: A0A1B2LZJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS03140
gene id: 1789224:BFG52_RS03140
uniprot id: A0A1B2LWX9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1789224:BFG52 RS14270
gene id: 1789224:BFG52_RS14270
uniprot id: A0A1B2M2I1
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

1789224:BFG52 RS13230
gene id: 1789224:BFG52_RS13230
uniprot id: A0A1B2M200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1789224:BFG52 RS09100
gene id: 1789224:BFG52_RS09100
uniprot id: A0A1B2LZX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1789224:BFG52 RS08475
gene id: 1789224:BFG52_RS08475
uniprot id: A0A1B2M449
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS14970
gene id: 1789224:BFG52_RS14970
uniprot id: A0A1B2M2U8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS11125
gene id: 1789224:BFG52_RS11125
uniprot id: A0A1B2M0Y1
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1789224:BFG52 RS04750
gene id: 1789224:BFG52_RS04750
uniprot id: A0A1B2LXT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1789224:BFG52 RS09925
gene id: 1789224:BFG52_RS09925
uniprot id: A0A1B2M0D1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1789224:BFG52 RS09990
gene id: 1789224:BFG52_RS09990
uniprot id: A0A1B2M0F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1789224:BFG52 RS03425
gene id: 1789224:BFG52_RS03425
uniprot id: A0A1B2LX39
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1789224:BFG52 RS01710
gene id: 1789224:BFG52_RS01710
uniprot id: A0A1B2LW61
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1789224:BFG52 RS06440
gene id: 1789224:BFG52_RS06440
uniprot id: A0A1B2LYM0
names: Similarity
messages: Belongs to the VgrG protein family.

1789224:BFG52 RS01985
gene id: 1789224:BFG52_RS01985
uniprot id: A0A1B2LWD6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1789224:BFG52 RS01585
gene id: 1789224:BFG52_RS01585
uniprot id: A0A1B2LW46
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1789224:BFG52 RS04400
gene id: 1789224:BFG52_RS04400
uniprot id: A0A1B2LXI2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1789224:BFG52 RS01215
gene id: 1789224:BFG52_RS01215
uniprot id: A0A1B2LW06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1789224:BFG52 RS09830
gene id: 1789224:BFG52_RS09830
uniprot id: A0A1B2M0D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS00230
gene id: 1789224:BFG52_RS00230
uniprot id: A0A1B2LVJ5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1789224:BFG52 RS06710
gene id: 1789224:BFG52_RS06710
uniprot id: A0A1B2LYN4
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1789224:BFG52 RS14535
gene id: 1789224:BFG52_RS14535
uniprot id: A0A1B2M2M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1789224:BFG52 RS01770
gene id: 1789224:BFG52_RS01770
uniprot id: A0A1B2LWA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1789224:BFG52 RS10840
gene id: 1789224:BFG52_RS10840
uniprot id: A0A1B2M0U5
names: Similarity
messages: Belongs to the isochorismate synthase family.

1789224:BFG52 RS01855
gene id: 1789224:BFG52_RS01855
uniprot id: A0A1B2LW91
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1789224:BFG52 RS12855
gene id: 1789224:BFG52_RS12855
uniprot id: A0A1B2M1T8
names: Similarity
messages: Belongs to the thioredoxin family.

1789224:BFG52 RS16430
gene id: 1789224:BFG52_RS16430
uniprot id: A0A1B2M3N6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1789224:BFG52 RS06540
gene id: 1789224:BFG52_RS06540
uniprot id: A0A1B2LYN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1789224:BFG52 RS05835
gene id: 1789224:BFG52_RS05835
uniprot id: A0A1B2LY91
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

1789224:BFG52 RS05925
gene id: 1789224:BFG52_RS05925
uniprot id: A0A1B2LYT0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1789224:BFG52 RS05640
gene id: 1789224:BFG52_RS05640
uniprot id: A0A1B2LYM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1789224:BFG52 RS10670
gene id: 1789224:BFG52_RS10670
uniprot id: A0A1B2M0R8
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS11505
gene id: 1789224:BFG52_RS11505
uniprot id: A0A1B2M141
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1789224:BFG52 RS12425
gene id: 1789224:BFG52_RS12425
uniprot id: A0A1B2M1K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1789224:BFG52 RS00475
gene id: 1789224:BFG52_RS00475
uniprot id: A0A1B2LVN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1789224:BFG52 RS13040
gene id: 1789224:BFG52_RS13040
uniprot id: A0A1B2M1W5
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1789224:BFG52 RS03360
gene id: 1789224:BFG52_RS03360
uniprot id: A0A1B2LX20
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS13505
gene id: 1789224:BFG52_RS13505
uniprot id: A0A1B2M255
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1789224:BFG52 RS02060
gene id: 1789224:BFG52_RS02060
uniprot id: A0A1B2LWE7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1789224:BFG52 RS04390
gene id: 1789224:BFG52_RS04390
uniprot id: A0A1B2LXL6
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS12960
gene id: 1789224:BFG52_RS12960
uniprot id: A0A1B2M4C6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1789224:BFG52 RS10340
gene id: 1789224:BFG52_RS10340
uniprot id: A0A1B2M0J4
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS15435
gene id: 1789224:BFG52_RS15435
uniprot id: A0A1B2M391
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS13010
gene id: 1789224:BFG52_RS13010
uniprot id: A0A1B2M204
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1789224:BFG52 RS00310
gene id: 1789224:BFG52_RS00310
uniprot id: A0A1B2LVM1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1789224:BFG52 RS11655
gene id: 1789224:BFG52_RS11655
uniprot id: A0A1B2M163
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1789224:BFG52 RS07105
gene id: 1789224:BFG52_RS07105
uniprot id: A0A1B2LYX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS08780
gene id: 1789224:BFG52_RS08780
uniprot id: A0A1B2LZT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS04005
gene id: 1789224:BFG52_RS04005
uniprot id: A0A1B2LXI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1789224:BFG52 RS01850
gene id: 1789224:BFG52_RS01850
uniprot id: A0A1B2LWF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1789224:BFG52 RS09755
gene id: 1789224:BFG52_RS09755
uniprot id: A0A1B2M0A2
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS10045
gene id: 1789224:BFG52_RS10045
uniprot id: A0A1B2M0E8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1789224:BFG52 RS04625
gene id: 1789224:BFG52_RS04625
uniprot id: A0A1B2LXQ2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1789224:BFG52 RS15175
gene id: 1789224:BFG52_RS15175
uniprot id: A0A1B2M2Y7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1789224:BFG52 RS09600
gene id: 1789224:BFG52_RS09600
uniprot id: A0A1B2M094
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1789224:BFG52 RS15680
gene id: 1789224:BFG52_RS15680
uniprot id: A0A1B2M389
names: Similarity
messages: Belongs to the RecJ family.

1789224:BFG52 RS16305
gene id: 1789224:BFG52_RS16305
uniprot id: A0A1B2M3I0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS10140
gene id: 1789224:BFG52_RS10140
uniprot id: A0A1B2M0H1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1789224:BFG52 RS14805
gene id: 1789224:BFG52_RS14805
uniprot id: A0A1B2M2S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1789224:BFG52 RS00405
gene id: 1789224:BFG52_RS00405
uniprot id: A0A1B2LVL8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1789224:BFG52 RS04580
gene id: 1789224:BFG52_RS04580
uniprot id: A0A1B2LY57
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS01420
gene id: 1789224:BFG52_RS01420
uniprot id: A0A1B2LW23
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1789224:BFG52 RS02745
gene id: 1789224:BFG52_RS02745
uniprot id: A0A1B2LX78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1789224:BFG52 RS02975
gene id: 1789224:BFG52_RS02975
uniprot id: A0A1B2LWV0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1789224:BFG52 RS05365
gene id: 1789224:BFG52_RS05365
uniprot id: A0A1B2LY26
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1789224:BFG52 RS02195
gene id: 1789224:BFG52_RS02195
uniprot id: A0A1B2LWI2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1789224:BFG52 RS13225
gene id: 1789224:BFG52_RS13225
uniprot id: A0A1B2M206
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1789224:BFG52 RS02960
gene id: 1789224:BFG52_RS02960
uniprot id: A0A1B2LXB2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1789224:BFG52 RS06385
gene id: 1789224:BFG52_RS06385
uniprot id: A0A1B2LYK9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1789224:BFG52 RS12670
gene id: 1789224:BFG52_RS12670
uniprot id: A0A1B2M1Q8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1789224:BFG52 RS13990
gene id: 1789224:BFG52_RS13990
uniprot id: A0A1B2M2E4
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS01360
gene id: 1789224:BFG52_RS01360
uniprot id: A0A1B2LW08
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1789224:BFG52 RS03390
gene id: 1789224:BFG52_RS03390
uniprot id: A0A1B2LX22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1789224:BFG52 RS15880
gene id: 1789224:BFG52_RS15880
uniprot id: A0A1B2M3C0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1789224:BFG52 RS15740
gene id: 1789224:BFG52_RS15740
uniprot id: A0A1B2M378
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1789224:BFG52 RS09255
gene id: 1789224:BFG52_RS09255
uniprot id: A0A1B2M000
names: Similarity
messages: Belongs to the NAPRTase family.

1789224:BFG52 RS15370
gene id: 1789224:BFG52_RS15370
uniprot id: A0A1B2M315
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1789224:BFG52 RS05220
gene id: 1789224:BFG52_RS05220
uniprot id: A0A1B2LXZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1789224:BFG52 RS12055
gene id: 1789224:BFG52_RS12055
uniprot id: A0A1B2M496
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1789224:BFG52 RS11650
gene id: 1789224:BFG52_RS11650
uniprot id: A0A1B2M1B2
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1789224:BFG52 RS12875
gene id: 1789224:BFG52_RS12875
uniprot id: A0A1B2M1T4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1789224:BFG52 RS09775
gene id: 1789224:BFG52_RS09775
uniprot id: A0A1B2M0A6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS14780
gene id: 1789224:BFG52_RS14780
uniprot id: A0A1B2M2R9
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS08840
gene id: 1789224:BFG52_RS08840
uniprot id: A0A1B2LZV5
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1789224:BFG52 RS10130
gene id: 1789224:BFG52_RS10130
uniprot id: A0A1B2M0E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1789224:BFG52 RS01410
gene id: 1789224:BFG52_RS01410
uniprot id: A0A1B2LW11
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1789224:BFG52 RS05840
gene id: 1789224:BFG52_RS05840
uniprot id: A0A1B2LY89
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS05845
gene id: 1789224:BFG52_RS05845
uniprot id: A0A1B2LYF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS12220
gene id: 1789224:BFG52_RS12220
uniprot id: A0A1B2M1G9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS04375
gene id: 1789224:BFG52_RS04375
uniprot id: A0A1B2LXJ5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1789224:BFG52 RS06685
gene id: 1789224:BFG52_RS06685
uniprot id: A0A1B2LYP6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1789224:BFG52 RS12195
gene id: 1789224:BFG52_RS12195
uniprot id: A0A1B2M1Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1789224:BFG52 RS16365
gene id: 1789224:BFG52_RS16365
uniprot id: A0A1B2M3I9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1789224:BFG52 RS15865
gene id: 1789224:BFG52_RS15865
uniprot id: A0A1B2M3C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1789224:BFG52 RS03990
gene id: 1789224:BFG52_RS03990
uniprot id: A0A1B2LXD6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1789224:BFG52 RS12455
gene id: 1789224:BFG52_RS12455
uniprot id: A0A1B2M1Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1789224:BFG52 RS03955
gene id: 1789224:BFG52_RS03955
uniprot id: A0A1B2LXD2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1789224:BFG52 RS11870
gene id: 1789224:BFG52_RS11870
uniprot id: A0A1B2M1B5
names: Similarity
messages: Belongs to the peptidase S11 family.

1789224:BFG52 RS05135
gene id: 1789224:BFG52_RS05135
uniprot id: A0A1B2LXX3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1789224:BFG52 RS06315
gene id: 1789224:BFG52_RS06315
uniprot id: A0A1B2LYJ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1789224:BFG52 RS13375
gene id: 1789224:BFG52_RS13375
uniprot id: A0A1B2M2K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1789224:BFG52 RS00515
gene id: 1789224:BFG52_RS00515
uniprot id: A0A1B2LVN4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1789224:BFG52 RS16275
gene id: 1789224:BFG52_RS16275
uniprot id: A0A1B2M3H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS13295
gene id: 1789224:BFG52_RS13295
uniprot id: A0A1B2M225
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS15660
gene id: 1789224:BFG52_RS15660
uniprot id: A0A1B2M365
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1789224:BFG52 RS15735
gene id: 1789224:BFG52_RS15735
uniprot id: A0A1B2M377
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1789224:BFG52 RS12665
gene id: 1789224:BFG52_RS12665
uniprot id: A0A1B2M1U0
names: Similarity
messages: Belongs to the GST superfamily.

1789224:BFG52 RS06285
gene id: 1789224:BFG52_RS06285
uniprot id: A0A1B2LYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1789224:BFG52 RS02765
gene id: 1789224:BFG52_RS02765
uniprot id: A0A1B2LWS7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1789224:BFG52 RS13195
gene id: 1789224:BFG52_RS13195
uniprot id: A0A1B2M201
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1789224:BFG52 RS02825
gene id: 1789224:BFG52_RS02825
uniprot id: A0A1B2LWS4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS00395
gene id: 1789224:BFG52_RS00395
uniprot id: A0A1B2LVM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1789224:BFG52 RS04575
gene id: 1789224:BFG52_RS04575
uniprot id: A0A1B2LXL0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1789224:BFG52 RS08490
gene id: 1789224:BFG52_RS08490
uniprot id: A0A1B2LZK4
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1789224:BFG52 RS11855
gene id: 1789224:BFG52_RS11855
uniprot id: A0A1B2M1B7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS12805
gene id: 1789224:BFG52_RS12805
uniprot id: A0A1B2M295
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1789224:BFG52 RS14320
gene id: 1789224:BFG52_RS14320
uniprot id: A0A1B2M2I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS15625
gene id: 1789224:BFG52_RS15625
uniprot id: A0A1B2M357
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS05405
gene id: 1789224:BFG52_RS05405
uniprot id: A0A1B2LY21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1789224:BFG52 RS01110
gene id: 1789224:BFG52_RS01110
uniprot id: A0A1B2LVY8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1789224:BFG52 RS05655
gene id: 1789224:BFG52_RS05655
uniprot id: A0A1B2LY78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1789224:BFG52 RS09805
gene id: 1789224:BFG52_RS09805
uniprot id: A0A1B2M092
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1789224:BFG52 RS13850
gene id: 1789224:BFG52_RS13850
uniprot id: A0A1B2M2T1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1789224:BFG52 RS08970
gene id: 1789224:BFG52_RS08970
uniprot id: A0A1B2LZV6
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

1789224:BFG52 RS10070
gene id: 1789224:BFG52_RS10070
uniprot id: A0A1B2M0G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1789224:BFG52 RS05125
gene id: 1789224:BFG52_RS05125
uniprot id: A0A1B2M3Y7
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1789224:BFG52 RS15030
gene id: 1789224:BFG52_RS15030
uniprot id: A0A1B2M317
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1789224:BFG52 RS09185
gene id: 1789224:BFG52_RS09185
uniprot id: A0A1B2LZY7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1789224:BFG52 RS15920
gene id: 1789224:BFG52_RS15920
uniprot id: A0A1B2M3C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1789224:BFG52 RS14355
gene id: 1789224:BFG52_RS14355
uniprot id: A0A1B2M2J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1789224:BFG52 RS12990
gene id: 1789224:BFG52_RS12990
uniprot id: A0A1B2M1V1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1789224:BFG52 RS13800
gene id: 1789224:BFG52_RS13800
uniprot id: A0A1B2M475
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1789224:BFG52 RS16500
gene id: 1789224:BFG52_RS16500
uniprot id: A0A1B2M3S7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS12615
gene id: 1789224:BFG52_RS12615
uniprot id: A0A1B2M1P8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1789224:BFG52 RS00265
gene id: 1789224:BFG52_RS00265
uniprot id: A0A1B2LVK2
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1789224:BFG52 RS08920
gene id: 1789224:BFG52_RS08920
uniprot id: A0A1B2M098
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1789224:BFG52 RS01200
gene id: 1789224:BFG52_RS01200
uniprot id: A0A1B2LVW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1789224:BFG52 RS03705
gene id: 1789224:BFG52_RS03705
uniprot id: A0A1B2M3U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1789224:BFG52 RS10205
gene id: 1789224:BFG52_RS10205
uniprot id: A0A1B2M0J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1789224:BFG52 RS14370
gene id: 1789224:BFG52_RS14370
uniprot id: A0A1B2M2K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1789224:BFG52 RS15635
gene id: 1789224:BFG52_RS15635
uniprot id: A0A1B2M4D9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS08345
gene id: 1789224:BFG52_RS08345
uniprot id: A0A1B2LZI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1789224:BFG52 RS12175
gene id: 1789224:BFG52_RS12175
uniprot id: A0A1B2M1F7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1789224:BFG52 RS09105
gene id: 1789224:BFG52_RS09105
uniprot id: A0A1B2M447
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS16475
gene id: 1789224:BFG52_RS16475
uniprot id: A0A1B2M3M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1789224:BFG52 RS06605
gene id: 1789224:BFG52_RS06605
uniprot id: A0A1B2LZ47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1789224:BFG52 RS04660
gene id: 1789224:BFG52_RS04660
uniprot id: A0A1B2LXP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS00315
gene id: 1789224:BFG52_RS00315
uniprot id: A0A1B2LVL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1789224:BFG52 RS05440
gene id: 1789224:BFG52_RS05440
uniprot id: A0A1B2LY35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1789224:BFG52 RS09465
gene id: 1789224:BFG52_RS09465
uniprot id: A0A1B2M036
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1789224:BFG52 RS12025
gene id: 1789224:BFG52_RS12025
uniprot id: A0A1B2M1E5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS15515
gene id: 1789224:BFG52_RS15515
uniprot id: A0A1B2M360
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS05465
gene id: 1789224:BFG52_RS05465
uniprot id: A0A1B2LY47
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1789224:BFG52 RS10485
gene id: 1789224:BFG52_RS10485
uniprot id: A0A1B2M0L7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1789224:BFG52 RS00365
gene id: 1789224:BFG52_RS00365
uniprot id: A0A1B2LVL6
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1789224:BFG52 RS04385
gene id: 1789224:BFG52_RS04385
uniprot id: A0A1B2LXQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1789224:BFG52 RS07180
gene id: 1789224:BFG52_RS07180
uniprot id: A0A1B2LZ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS12085
gene id: 1789224:BFG52_RS12085
uniprot id: A0A1B2M1D8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1789224:BFG52 RS15260
gene id: 1789224:BFG52_RS15260
uniprot id: A0A1B2M2Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1789224:BFG52 RS13175
gene id: 1789224:BFG52_RS13175
uniprot id: A0A1B2M1Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS16260
gene id: 1789224:BFG52_RS16260
uniprot id: A0A1B2M3H5
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1789224:BFG52 RS15545
gene id: 1789224:BFG52_RS15545
uniprot id: A0A1B2M341
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1789224:BFG52 RS06375
gene id: 1789224:BFG52_RS06375
uniprot id: A0A1B2LZ08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1789224:BFG52 RS11825
gene id: 1789224:BFG52_RS11825
uniprot id: A0A1B2M1C5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1789224:BFG52 RS01495
gene id: 1789224:BFG52_RS01495
uniprot id: A0A1B2LW56
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS00065
gene id: 1789224:BFG52_RS00065
uniprot id: A0A1B2LVX5
names: Function
names: Similarity
messages: Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
messages: Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia.

1789224:BFG52 RS04135
gene id: 1789224:BFG52_RS04135
uniprot id: A0A1B2LXD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS04795
gene id: 1789224:BFG52_RS04795
uniprot id: A0A1B2LXT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1789224:BFG52 RS06665
gene id: 1789224:BFG52_RS06665
uniprot id: A0A1B2LZ58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1789224:BFG52 RS00010
gene id: 1789224:BFG52_RS00010
uniprot id: A0A1B2LVE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1789224:BFG52 RS10855
gene id: 1789224:BFG52_RS10855
uniprot id: A0A1B2M0S7
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

1789224:BFG52 RS11150
gene id: 1789224:BFG52_RS11150
uniprot id: A0A1B2M0Z4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS12830
gene id: 1789224:BFG52_RS12830
uniprot id: A0A1B2M1T3
names: Similarity
messages: Belongs to the YggT family.

1789224:BFG52 RS13150
gene id: 1789224:BFG52_RS13150
uniprot id: A0A1B2M211
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1789224:BFG52 RS14930
gene id: 1789224:BFG52_RS14930
uniprot id: A0A1B2M2U6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1789224:BFG52 RS03590
gene id: 1789224:BFG52_RS03590
uniprot id: A0A1B2LX69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1789224:BFG52 RS16445
gene id: 1789224:BFG52_RS16445
uniprot id: A0A1B2M3Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1789224:BFG52 RS14255
gene id: 1789224:BFG52_RS14255
uniprot id: A0A1B2M2G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS13290
gene id: 1789224:BFG52_RS13290
uniprot id: A0A1B2M218
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1789224:BFG52 RS14975
gene id: 1789224:BFG52_RS14975
uniprot id: A0A1B2M308
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

1789224:BFG52 RS05575
gene id: 1789224:BFG52_RS05575
uniprot id: A0A1B2LYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1789224:BFG52 RS12555
gene id: 1789224:BFG52_RS12555
uniprot id: A0A1B2M1S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1789224:BFG52 RS14925
gene id: 1789224:BFG52_RS14925
uniprot id: A0A1B2M302
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS16485
gene id: 1789224:BFG52_RS16485
uniprot id: A0A1B2M3P0
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1789224:BFG52 RS00535
gene id: 1789224:BFG52_RS00535
uniprot id: A0A1B2LVL7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1789224:BFG52 RS03625
gene id: 1789224:BFG52_RS03625
uniprot id: A0A1B2LX71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1789224:BFG52 RS02045
gene id: 1789224:BFG52_RS02045
uniprot id: A0A1B2LWE3
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS14425
gene id: 1789224:BFG52_RS14425
uniprot id: A0A1B2M2K5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1789224:BFG52 RS06430
gene id: 1789224:BFG52_RS06430
uniprot id: A0A1B2LZ18
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1789224:BFG52 RS13255
gene id: 1789224:BFG52_RS13255
uniprot id: A0A1B2M208
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1789224:BFG52 RS12725
gene id: 1789224:BFG52_RS12725
uniprot id: A0A1B2M1R8
names: Similarity
messages: Belongs to the UPF0234 family.

1789224:BFG52 RS06920
gene id: 1789224:BFG52_RS06920
uniprot id: A0A1B2LYY9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS08905
gene id: 1789224:BFG52_RS08905
uniprot id: A0A1B2LZU7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1789224:BFG52 RS06200
gene id: 1789224:BFG52_RS06200
uniprot id: A0A1B2LYG0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1789224:BFG52 RS14305
gene id: 1789224:BFG52_RS14305
uniprot id: A0A1B2M2H8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1789224:BFG52 RS11550
gene id: 1789224:BFG52_RS11550
uniprot id: A0A1B2M1M9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1789224:BFG52 RS15250
gene id: 1789224:BFG52_RS15250
uniprot id: A0A1B2M2Y4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1789224:BFG52 RS11325
gene id: 1789224:BFG52_RS11325
uniprot id: A0A1B2M130
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1789224:BFG52 RS11750
gene id: 1789224:BFG52_RS11750
uniprot id: A0A1B2M181
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1789224:BFG52 RS12420
gene id: 1789224:BFG52_RS12420
uniprot id: A0A1B2M1K7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1789224:BFG52 RS06155
gene id: 1789224:BFG52_RS06155
uniprot id: A0A1B2LYD7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1789224:BFG52 RS14910
gene id: 1789224:BFG52_RS14910
uniprot id: A0A1B2M2U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS11380
gene id: 1789224:BFG52_RS11380
uniprot id: A0A1B2M138
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1789224:BFG52 RS11005
gene id: 1789224:BFG52_RS11005
uniprot id: A0A1B2M0U1
names: Similarity
messages: Belongs to the TmoD/XamoD family.

1789224:BFG52 RS13860
gene id: 1789224:BFG52_RS13860
uniprot id: A0A1B2M2B1
names: Similarity
messages: Belongs to the catalase family.

1789224:BFG52 RS11250
gene id: 1789224:BFG52_RS11250
uniprot id: A0A1B2M1I1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1789224:BFG52 RS04370
gene id: 1789224:BFG52_RS04370
uniprot id: A0A1B2LXK3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1789224:BFG52 RS09460
gene id: 1789224:BFG52_RS09460
uniprot id: A0A1B2M035
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1789224:BFG52 RS00505
gene id: 1789224:BFG52_RS00505
uniprot id: A0A1B2LVP1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1789224:BFG52 RS02110
gene id: 1789224:BFG52_RS02110
uniprot id: A0A1B2LWF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1789224:BFG52 RS06960
gene id: 1789224:BFG52_RS06960
uniprot id: A0A1B2LYV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1789224:BFG52 RS14115
gene id: 1789224:BFG52_RS14115
uniprot id: A0A1B2M2G4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS04665
gene id: 1789224:BFG52_RS04665
uniprot id: A0A1B2LXN9
names: Cofactor
messages: Can also use Mn(2+) ion.

1789224:BFG52 RS14280
gene id: 1789224:BFG52_RS14280
uniprot id: A0A1B2M2H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS10950
gene id: 1789224:BFG52_RS10950
uniprot id: A0A1B2M0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

1789224:BFG52 RS04675
gene id: 1789224:BFG52_RS04675
uniprot id: A0A1B2LXR2
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1789224:BFG52 RS04435
gene id: 1789224:BFG52_RS04435
uniprot id: A0A1B2LXR4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS11170
gene id: 1789224:BFG52_RS11170
uniprot id: A0A1B2M116
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1789224:BFG52 RS08340
gene id: 1789224:BFG52_RS08340
uniprot id: A0A1B2LZM8
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS12675
gene id: 1789224:BFG52_RS12675
uniprot id: A0A1B2M275
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS02170
gene id: 1789224:BFG52_RS02170
uniprot id: A0A1B2LWL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1789224:BFG52 RS02690
gene id: 1789224:BFG52_RS02690
uniprot id: A0A1B2LWN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1789224:BFG52 RS15750
gene id: 1789224:BFG52_RS15750
uniprot id: A0A1B2M381
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1789224:BFG52 RS09525
gene id: 1789224:BFG52_RS09525
uniprot id: A0A1B2M060
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS14005
gene id: 1789224:BFG52_RS14005
uniprot id: A0A1B2M2D7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1789224:BFG52 RS00615
gene id: 1789224:BFG52_RS00615
uniprot id: A0A1B2LVQ9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1789224:BFG52 RS12915
gene id: 1789224:BFG52_RS12915
uniprot id: A0A1B2M2B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1789224:BFG52 RS03505
gene id: 1789224:BFG52_RS03505
uniprot id: A0A1B2LX49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1789224:BFG52 RS12870
gene id: 1789224:BFG52_RS12870
uniprot id: A0A1B2M1T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1789224:BFG52 RS14130
gene id: 1789224:BFG52_RS14130
uniprot id: A0A1B2M2F8
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1789224:BFG52 RS13700
gene id: 1789224:BFG52_RS13700
uniprot id: A0A1B2M288
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1789224:BFG52 RS01020
gene id: 1789224:BFG52_RS01020
uniprot id: A0A1B2LVT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1789224:BFG52 RS00680
gene id: 1789224:BFG52_RS00680
uniprot id: A0A1B2LVR8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1789224:BFG52 RS16035
gene id: 1789224:BFG52_RS16035
uniprot id: A0A1B2M4H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS11725
gene id: 1789224:BFG52_RS11725
uniprot id: A0A1B2M1C1
names: Similarity
messages: Belongs to the PhzF family.

1789224:BFG52 RS06575
gene id: 1789224:BFG52_RS06575
uniprot id: A0A1B2LYL7
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS09370
gene id: 1789224:BFG52_RS09370
uniprot id: A0A1B2M028
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS05145
gene id: 1789224:BFG52_RS05145
uniprot id: A0A1B2LXY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1789224:BFG52 RS01210
gene id: 1789224:BFG52_RS01210
uniprot id: A0A1B2LWG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1789224:BFG52 RS02660
gene id: 1789224:BFG52_RS02660
uniprot id: A0A1B2LWP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1789224:BFG52 RS11700
gene id: 1789224:BFG52_RS11700
uniprot id: A0A1B2M173
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1789224:BFG52 RS12100
gene id: 1789224:BFG52_RS12100
uniprot id: A0A1B2M1H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1789224:BFG52 RS13790
gene id: 1789224:BFG52_RS13790
uniprot id: A0A1B2M2A8
names: Similarity
messages: Belongs to the peptidase S41A family.

1789224:BFG52 RS13920
gene id: 1789224:BFG52_RS13920
uniprot id: A0A1B2M2C9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1789224:BFG52 RS09270
gene id: 1789224:BFG52_RS09270
uniprot id: A0A1B2M008
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

1789224:BFG52 RS12005
gene id: 1789224:BFG52_RS12005
uniprot id: A0A1B2M1D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1789224:BFG52 RS00020
gene id: 1789224:BFG52_RS00020
uniprot id: A0A1B2LVH0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1789224:BFG52 RS11130
gene id: 1789224:BFG52_RS11130
uniprot id: A0A1B2M113
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1789224:BFG52 RS04340
gene id: 1789224:BFG52_RS04340
uniprot id: A0A1B2LXJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1789224:BFG52 RS01830
gene id: 1789224:BFG52_RS01830
uniprot id: A0A1B2LW87
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1789224:BFG52 RS10020
gene id: 1789224:BFG52_RS10020
uniprot id: A0A1B2M0F3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1789224:BFG52 RS05970
gene id: 1789224:BFG52_RS05970
uniprot id: A0A1B2LYC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1789224:BFG52 RS02535
gene id: 1789224:BFG52_RS02535
uniprot id: A0A1B2LX36
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1789224:BFG52 RS05205
gene id: 1789224:BFG52_RS05205
uniprot id: A0A1B2M3U9
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1789224:BFG52 RS08435
gene id: 1789224:BFG52_RS08435
uniprot id: A0A1B2LZJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1789224:BFG52 RS10600
gene id: 1789224:BFG52_RS10600
uniprot id: A0A1B2M157
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1789224:BFG52 RS08480
gene id: 1789224:BFG52_RS08480
uniprot id: A0A1B2LZL7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS12435
gene id: 1789224:BFG52_RS12435
uniprot id: A0A1B2M1K1
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1789224:BFG52 RS02135
gene id: 1789224:BFG52_RS02135
uniprot id: A0A1B2LWE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1789224:BFG52 RS11195
gene id: 1789224:BFG52_RS11195
uniprot id: A0A1B2M1H0
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS03915
gene id: 1789224:BFG52_RS03915
uniprot id: A0A1B2LXU4
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1789224:BFG52 RS10125
gene id: 1789224:BFG52_RS10125
uniprot id: A0A1B2M0H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1789224:BFG52 RS00995
gene id: 1789224:BFG52_RS00995
uniprot id: A0A1B2LVV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1789224:BFG52 RS12475
gene id: 1789224:BFG52_RS12475
uniprot id: A0A1B2M1L7
names: Similarity
messages: Belongs to the GSP E family.

1789224:BFG52 RS09425
gene id: 1789224:BFG52_RS09425
uniprot id: A0A1B2M053
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1789224:BFG52 RS13205
gene id: 1789224:BFG52_RS13205
uniprot id: A0A1B2M1Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1789224:BFG52 RS02540
gene id: 1789224:BFG52_RS02540
uniprot id: A0A1B2LWP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1789224:BFG52 RS03420
gene id: 1789224:BFG52_RS03420
uniprot id: A0A1B2LX30
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS10015
gene id: 1789224:BFG52_RS10015
uniprot id: A0A1B2M0C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1789224:BFG52 RS15685
gene id: 1789224:BFG52_RS15685
uniprot id: A0A1B2M367
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS00180
gene id: 1789224:BFG52_RS00180
uniprot id: A0A1B2LVI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS06995
gene id: 1789224:BFG52_RS06995
uniprot id: A0A1B2LYV1
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1789224:BFG52 RS10595
gene id: 1789224:BFG52_RS10595
uniprot id: A0A1B2M0N0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS01540
gene id: 1789224:BFG52_RS01540
uniprot id: A0A1B2LW41
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS16095
gene id: 1789224:BFG52_RS16095
uniprot id: A0A1B2M3E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS05790
gene id: 1789224:BFG52_RS05790
uniprot id: A0A1B2LY97
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1789224:BFG52 RS02385
gene id: 1789224:BFG52_RS02385
uniprot id: A0A1B2M461
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1789224:BFG52 RS00305
gene id: 1789224:BFG52_RS00305
uniprot id: A0A1B2LW09
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1789224:BFG52 RS16060
gene id: 1789224:BFG52_RS16060
uniprot id: A0A1B2M3J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1789224:BFG52 RS06115
gene id: 1789224:BFG52_RS06115
uniprot id: A0A1B2LYE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS06785
gene id: 1789224:BFG52_RS06785
uniprot id: A0A1B2LYT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS13530
gene id: 1789224:BFG52_RS13530
uniprot id: A0A1B2M2M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1789224:BFG52 RS13775
gene id: 1789224:BFG52_RS13775
uniprot id: A0A1B2M2C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1789224:BFG52 RS00635
gene id: 1789224:BFG52_RS00635
uniprot id: A0A1B2LVQ0
names: Similarity
messages: Belongs to the peptidase C59 family.

1789224:BFG52 RS11520
gene id: 1789224:BFG52_RS11520
uniprot id: A0A1B2M158
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1789224:BFG52 RS05130
gene id: 1789224:BFG52_RS05130
uniprot id: A0A1B2LYE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1789224:BFG52 RS04165
gene id: 1789224:BFG52_RS04165
uniprot id: A0A1B2LXF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1789224:BFG52 RS01090
gene id: 1789224:BFG52_RS01090
uniprot id: A0A1B2LVU8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1789224:BFG52 RS13380
gene id: 1789224:BFG52_RS13380
uniprot id: A0A1B2M237
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1789224:BFG52 RS04620
gene id: 1789224:BFG52_RS04620
uniprot id: A0A1B2LXU7
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS12340
gene id: 1789224:BFG52_RS12340
uniprot id: A0A1B2M1N2
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS14630
gene id: 1789224:BFG52_RS14630
uniprot id: A0A1B2M2T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1789224:BFG52 RS15570
gene id: 1789224:BFG52_RS15570
uniprot id: A0A1B2M351
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1789224:BFG52 RS03380
gene id: 1789224:BFG52_RS03380
uniprot id: A0A1B2LX17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS15145
gene id: 1789224:BFG52_RS15145
uniprot id: A0A1B2M2Y2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1789224:BFG52 RS01120
gene id: 1789224:BFG52_RS01120
uniprot id: A0A1B2LVX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1789224:BFG52 RS06555
gene id: 1789224:BFG52_RS06555
uniprot id: A0A1B2LYM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1789224:BFG52 RS05905
gene id: 1789224:BFG52_RS05905
uniprot id: A0A1B2LYB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1789224:BFG52 RS10450
gene id: 1789224:BFG52_RS10450
uniprot id: A0A1B2M0L8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1789224:BFG52 RS07060
gene id: 1789224:BFG52_RS07060
uniprot id: A0A1B2LYY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS10090
gene id: 1789224:BFG52_RS10090
uniprot id: A0A1B2M0G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1789224:BFG52 RS01475
gene id: 1789224:BFG52_RS01475
uniprot id: A0A1B2LW34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

1789224:BFG52 RS09615
gene id: 1789224:BFG52_RS09615
uniprot id: A0A1B2M058
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1789224:BFG52 RS00585
gene id: 1789224:BFG52_RS00585
uniprot id: A0A1B2LVN9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1789224:BFG52 RS01450
gene id: 1789224:BFG52_RS01450
uniprot id: A0A1B2LW29
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1789224:BFG52 RS05355
gene id: 1789224:BFG52_RS05355
uniprot id: A0A1B2LY09
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS04925
gene id: 1789224:BFG52_RS04925
uniprot id: A0A1B2LXV9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1789224:BFG52 RS01795
gene id: 1789224:BFG52_RS01795
uniprot id: A0A1B2LWE1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS05955
gene id: 1789224:BFG52_RS05955
uniprot id: A0A1B2LYB4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1789224:BFG52 RS10665
gene id: 1789224:BFG52_RS10665
uniprot id: A0A1B2M0N1
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS03015
gene id: 1789224:BFG52_RS03015
uniprot id: A0A1B2LXC1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1789224:BFG52 RS04070
gene id: 1789224:BFG52_RS04070
uniprot id: A0A1B2LXE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1789224:BFG52 RS13590
gene id: 1789224:BFG52_RS13590
uniprot id: A0A1B2M261
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1789224:BFG52 RS04565
gene id: 1789224:BFG52_RS04565
uniprot id: A0A1B2M3T9
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS03020
gene id: 1789224:BFG52_RS03020
uniprot id: A0A1B2LWW3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS16220
gene id: 1789224:BFG52_RS16220
uniprot id: A0A1B2M3I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS06230
gene id: 1789224:BFG52_RS06230
uniprot id: A0A1B2LYH8
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1789224:BFG52 RS04860
gene id: 1789224:BFG52_RS04860
uniprot id: A0A1B2LXQ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS02705
gene id: 1789224:BFG52_RS02705
uniprot id: A0A1B2LWR5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1789224:BFG52 RS16385
gene id: 1789224:BFG52_RS16385
uniprot id: A0A1B2M3J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1789224:BFG52 RS01455
gene id: 1789224:BFG52_RS01455
uniprot id: A0A1B2LW38
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1789224:BFG52 RS15730
gene id: 1789224:BFG52_RS15730
uniprot id: A0A1B2M3A4
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1789224:BFG52 RS13810
gene id: 1789224:BFG52_RS13810
uniprot id: A0A1B2M2A2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1789224:BFG52 RS00600
gene id: 1789224:BFG52_RS00600
uniprot id: A0A1B2M431
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1789224:BFG52 RS00080
gene id: 1789224:BFG52_RS00080
uniprot id: A0A1B2LVH2
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1789224:BFG52 RS05780
gene id: 1789224:BFG52_RS05780
uniprot id: A0A1B2LY79
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1789224:BFG52 RS07020
gene id: 1789224:BFG52_RS07020
uniprot id: A0A1B2LZ06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1789224:BFG52 RS14120
gene id: 1789224:BFG52_RS14120
uniprot id: A0A1B2M2G1
names: Similarity
messages: Belongs to the BolA/IbaG family.

1789224:BFG52 RS08730
gene id: 1789224:BFG52_RS08730
uniprot id: A0A1B2M401
names: Similarity
messages: Belongs to the peptidase M1 family.

1789224:BFG52 RS00400
gene id: 1789224:BFG52_RS00400
uniprot id: A0A1B2LVL5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1789224:BFG52 RS08595
gene id: 1789224:BFG52_RS08595
uniprot id: A0A1B2LZN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1789224:BFG52 RS07875
gene id: 1789224:BFG52_RS07875
uniprot id: A0A1B2LZS9
names: Similarity
messages: Belongs to the peptidase C40 family.

1789224:BFG52 RS16115
gene id: 1789224:BFG52_RS16115
uniprot id: A0A1B2M3E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1789224:BFG52 RS04900
gene id: 1789224:BFG52_RS04900
uniprot id: A0A1B2LXU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS03355
gene id: 1789224:BFG52_RS03355
uniprot id: A0A1B2LX18
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1789224:BFG52 RS08935
gene id: 1789224:BFG52_RS08935
uniprot id: A0A1B2LZU4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1789224:BFG52 RS10290
gene id: 1789224:BFG52_RS10290
uniprot id: A0A1B2M0H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1789224:BFG52 RS09800
gene id: 1789224:BFG52_RS09800
uniprot id: A0A1B2M0B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1789224:BFG52 RS05250
gene id: 1789224:BFG52_RS05250
uniprot id: A0A1B2LY05
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1789224:BFG52 RS01945
gene id: 1789224:BFG52_RS01945
uniprot id: A0A1B2LWC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1789224:BFG52 RS00685
gene id: 1789224:BFG52_RS00685
uniprot id: A0A1B2LVQ6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1789224:BFG52 RS12335
gene id: 1789224:BFG52_RS12335
uniprot id: A0A1B2M1I4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS05865
gene id: 1789224:BFG52_RS05865
uniprot id: A0A1B2LYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

1789224:BFG52 RS07005
gene id: 1789224:BFG52_RS07005
uniprot id: A0A1B2LYX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1789224:BFG52 RS06345
gene id: 1789224:BFG52_RS06345
uniprot id: A0A1B2LYI6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1789224:BFG52 RS13035
gene id: 1789224:BFG52_RS13035
uniprot id: A0A1B2M1W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1789224:BFG52 RS03370
gene id: 1789224:BFG52_RS03370
uniprot id: A0A1B2M3S0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1789224:BFG52 RS05755
gene id: 1789224:BFG52_RS05755
uniprot id: A0A1B2LYP9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1789224:BFG52 RS04830
gene id: 1789224:BFG52_RS04830
uniprot id: A0A1B2LXT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS10390
gene id: 1789224:BFG52_RS10390
uniprot id: A0A1B2M438
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1789224:BFG52 RS11740
gene id: 1789224:BFG52_RS11740
uniprot id: A0A1B2M175
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS13560
gene id: 1789224:BFG52_RS13560
uniprot id: A0A1B2M280
names: Similarity
messages: Belongs to the FMO family.

1789224:BFG52 RS07010
gene id: 1789224:BFG52_RS07010
uniprot id: A0A1B2LYV9
names: Similarity
messages: Belongs to the HesB/IscA family.

1789224:BFG52 RS05815
gene id: 1789224:BFG52_RS05815
uniprot id: A0A1B2M410
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1789224:BFG52 RS09310
gene id: 1789224:BFG52_RS09310
uniprot id: A0A1B2M009
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1789224:BFG52 RS06085
gene id: 1789224:BFG52_RS06085
uniprot id: A0A1B2LYD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1789224:BFG52 RS15195
gene id: 1789224:BFG52_RS15195
uniprot id: A0A1B2M2X5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1789224:BFG52 RS04720
gene id: 1789224:BFG52_RS04720
uniprot id: A0A1B2LXW9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1789224:BFG52 RS06425
gene id: 1789224:BFG52_RS06425
uniprot id: A0A1B2M4C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1789224:BFG52 RS04030
gene id: 1789224:BFG52_RS04030
uniprot id: A0A1B2LXD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS09960
gene id: 1789224:BFG52_RS09960
uniprot id: A0A1B2M0A9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1789224:BFG52 RS14215
gene id: 1789224:BFG52_RS14215
uniprot id: A0A1B2M2G9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1789224:BFG52 RS10350
gene id: 1789224:BFG52_RS10350
uniprot id: A0A1B2M120
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

1789224:BFG52 RS07000
gene id: 1789224:BFG52_RS07000
uniprot id: A0A1B2LYW7
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1789224:BFG52 RS04130
gene id: 1789224:BFG52_RS04130
uniprot id: A0A1B2LXF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1789224:BFG52 RS05045
gene id: 1789224:BFG52_RS05045
uniprot id: A0A1B2LXX2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1789224:BFG52 RS06520
gene id: 1789224:BFG52_RS06520
uniprot id: A0A1B2LYK7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1789224:BFG52 RS04075
gene id: 1789224:BFG52_RS04075
uniprot id: A0A1B2LXC3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1789224:BFG52 RS01485
gene id: 1789224:BFG52_RS01485
uniprot id: A0A1B2LW35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS00790
gene id: 1789224:BFG52_RS00790
uniprot id: A0A1B2LVU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS00460
gene id: 1789224:BFG52_RS00460
uniprot id: A0A1B2LVM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1789224:BFG52 RS04010
gene id: 1789224:BFG52_RS04010
uniprot id: A0A1B2LXE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1789224:BFG52 RS03490
gene id: 1789224:BFG52_RS03490
uniprot id: A0A1B2M480
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1789224:BFG52 RS09985
gene id: 1789224:BFG52_RS09985
uniprot id: A0A1B2M442
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1789224:BFG52 RS04835
gene id: 1789224:BFG52_RS04835
uniprot id: A0A1B2LXS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS04410
gene id: 1789224:BFG52_RS04410
uniprot id: A0A1B2LXJ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS06875
gene id: 1789224:BFG52_RS06875
uniprot id: A0A1B2LYR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1789224:BFG52 RS03595
gene id: 1789224:BFG52_RS03595
uniprot id: A0A1B2LX70
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1789224:BFG52 RS02340
gene id: 1789224:BFG52_RS02340
uniprot id: A0A1B2LWP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS04160
gene id: 1789224:BFG52_RS04160
uniprot id: A0A1B2LXF7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1789224:BFG52 RS05155
gene id: 1789224:BFG52_RS05155
uniprot id: A0A1B2LXW8
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1789224:BFG52 RS14240
gene id: 1789224:BFG52_RS14240
uniprot id: A0A1B2M483
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1789224:BFG52 RS06515
gene id: 1789224:BFG52_RS06515
uniprot id: A0A1B2LYL6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1789224:BFG52 RS09735
gene id: 1789224:BFG52_RS09735
uniprot id: A0A1B2M0A7
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS06215
gene id: 1789224:BFG52_RS06215
uniprot id: A0A1B2LYF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1789224:BFG52 RS04125
gene id: 1789224:BFG52_RS04125
uniprot id: A0A1B2M3S9
names: Similarity
messages: Belongs to the UPF0145 family.

1789224:BFG52 RS10100
gene id: 1789224:BFG52_RS10100
uniprot id: A0A1B2M0F8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1789224:BFG52 RS14575
gene id: 1789224:BFG52_RS14575
uniprot id: A0A1B2M355
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1789224:BFG52 RS09220
gene id: 1789224:BFG52_RS09220
uniprot id: A0A1B2M022
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1789224:BFG52 RS13980
gene id: 1789224:BFG52_RS13980
uniprot id: A0A1B2M2D1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1789224:BFG52 RS04930
gene id: 1789224:BFG52_RS04930
uniprot id: A0A1B2LXV3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1789224:BFG52 RS09915
gene id: 1789224:BFG52_RS09915
uniprot id: A0A1B2M0A8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1789224:BFG52 RS13095
gene id: 1789224:BFG52_RS13095
uniprot id: A0A1B2M1Y3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS05120
gene id: 1789224:BFG52_RS05120
uniprot id: A0A1B2LXU5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1789224:BFG52 RS15160
gene id: 1789224:BFG52_RS15160
uniprot id: A0A1B2M2X6
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1789224:BFG52 RS10890
gene id: 1789224:BFG52_RS10890
uniprot id: A0A1B2M1A6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1789224:BFG52 RS11805
gene id: 1789224:BFG52_RS11805
uniprot id: A0A1B2M1A8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1789224:BFG52 RS15065
gene id: 1789224:BFG52_RS15065
uniprot id: A0A1B2M2W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1789224:BFG52 RS05115
gene id: 1789224:BFG52_RS05115
uniprot id: A0A1B2LXY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS05860
gene id: 1789224:BFG52_RS05860
uniprot id: A0A1B2LY85
names: Subcellular Location Annotation
messages: Cell inner membrane

1789224:BFG52 RS00290
gene id: 1789224:BFG52_RS00290
uniprot id: A0A1B2LVJ8
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1789224:BFG52 RS03000
gene id: 1789224:BFG52_RS03000
uniprot id: A0A1B2LWU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS13235
gene id: 1789224:BFG52_RS13235
uniprot id: A0A1B2M205
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1789224:BFG52 RS02585
gene id: 1789224:BFG52_RS02585
uniprot id: A0A1B2LWL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1789224:BFG52 RS15655
gene id: 1789224:BFG52_RS15655
uniprot id: A0A1B2M382
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1789224:BFG52 RS14380
gene id: 1789224:BFG52_RS14380
uniprot id: A0A1B2M2L4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1789224:BFG52 RS12580
gene id: 1789224:BFG52_RS12580
uniprot id: A0A1B2M464
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1789224:BFG52 RS02375
gene id: 1789224:BFG52_RS02375
uniprot id: A0A1B2LWK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS16145
gene id: 1789224:BFG52_RS16145
uniprot id: A0A1B2M3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS04430
gene id: 1789224:BFG52_RS04430
uniprot id: A0A1B2LXK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1789224:BFG52 RS03985
gene id: 1789224:BFG52_RS03985
uniprot id: A0A1B2LXD8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1789224:BFG52 RS15055
gene id: 1789224:BFG52_RS15055
uniprot id: A0A1B2M2V5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS14610
gene id: 1789224:BFG52_RS14610
uniprot id: A0A1B2M2N2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1789224:BFG52 RS11375
gene id: 1789224:BFG52_RS11375
uniprot id: A0A1B2M118
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1789224:BFG52 RS09710
gene id: 1789224:BFG52_RS09710
uniprot id: A0A1B2M095
names: Similarity
messages: Belongs to the IMPACT family.

1789224:BFG52 RS00420
gene id: 1789224:BFG52_RS00420
uniprot id: A0A1B2LVL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1789224:BFG52 RS16205
gene id: 1789224:BFG52_RS16205
uniprot id: A0A1B2M3G0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS02520
gene id: 1789224:BFG52_RS02520
uniprot id: A0A1B2LWM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1789224:BFG52 RS00850
gene id: 1789224:BFG52_RS00850
uniprot id: A0A1B2LVU3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1789224:BFG52 RS05400
gene id: 1789224:BFG52_RS05400
uniprot id: A0A1B2LYJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1789224:BFG52 RS06760
gene id: 1789224:BFG52_RS06760
uniprot id: A0A1B2LYP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1789224:BFG52 RS06240
gene id: 1789224:BFG52_RS06240
uniprot id: A0A1B2LYG5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1789224:BFG52 RS10870
gene id: 1789224:BFG52_RS10870
uniprot id: A0A1B2M0T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1789224:BFG52 RS15500
gene id: 1789224:BFG52_RS15500
uniprot id: A0A1B2M3A2
names: Similarity
messages: Belongs to the VgrG protein family.

1789224:BFG52 RS03050
gene id: 1789224:BFG52_RS03050
uniprot id: A0A1B2LWV9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS00640
gene id: 1789224:BFG52_RS00640
uniprot id: A0A1B2LVR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1789224:BFG52 RS05830
gene id: 1789224:BFG52_RS05830
uniprot id: A0A1B2LYA8
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1789224:BFG52 RS09965
gene id: 1789224:BFG52_RS09965
uniprot id: A0A1B2M0E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1789224:BFG52 RS11850
gene id: 1789224:BFG52_RS11850
uniprot id: A0A1B2M197
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1789224:BFG52 RS09980
gene id: 1789224:BFG52_RS09980
uniprot id: A0A1B2M0E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1789224:BFG52 RS03325
gene id: 1789224:BFG52_RS03325
uniprot id: A0A1B2LX08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS13575
gene id: 1789224:BFG52_RS13575
uniprot id: A0A1B2M268
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1789224:BFG52 RS11175
gene id: 1789224:BFG52_RS11175
uniprot id: A0A1B2M0Z5
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

1789224:BFG52 RS16000
gene id: 1789224:BFG52_RS16000
uniprot id: A0A1B2M3E2
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1789224:BFG52 RS05920
gene id: 1789224:BFG52_RS05920
uniprot id: A0A1B2M3Z9
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS13875
gene id: 1789224:BFG52_RS13875
uniprot id: A0A1B2M2C4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1789224:BFG52 RS16440
gene id: 1789224:BFG52_RS16440
uniprot id: A0A1B2M3R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1789224:BFG52 RS14140
gene id: 1789224:BFG52_RS14140
uniprot id: A0A1B2M2G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS04210
gene id: 1789224:BFG52_RS04210
uniprot id: A0A1B2LXH9
names: Similarity
messages: Belongs to the UPF0250 family.

1789224:BFG52 RS11095
gene id: 1789224:BFG52_RS11095
uniprot id: A0A1B2M0W5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1789224:BFG52 RS03225
gene id: 1789224:BFG52_RS03225
uniprot id: A0A1B2LWZ0
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS01045
gene id: 1789224:BFG52_RS01045
uniprot id: A0A1B2LWD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1789224:BFG52 RS02835
gene id: 1789224:BFG52_RS02835
uniprot id: A0A1B2LWS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1789224:BFG52 RS03610
gene id: 1789224:BFG52_RS03610
uniprot id: A0A1B2M3S4
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS08555
gene id: 1789224:BFG52_RS08555
uniprot id: A0A1B2LZL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1789224:BFG52 RS03545
gene id: 1789224:BFG52_RS03545
uniprot id: A0A1B2LX59
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS08680
gene id: 1789224:BFG52_RS08680
uniprot id: A0A1B2M056
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS12510
gene id: 1789224:BFG52_RS12510
uniprot id: A0A1B2M1M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1789224:BFG52 RS11875
gene id: 1789224:BFG52_RS11875
uniprot id: A0A1B2M1D4
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1789224:BFG52 RS16410
gene id: 1789224:BFG52_RS16410
uniprot id: A0A1B2M3K0
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1789224:BFG52 RS01820
gene id: 1789224:BFG52_RS01820
uniprot id: A0A1B2LWB5
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1789224:BFG52 RS07115
gene id: 1789224:BFG52_RS07115
uniprot id: A0A1B2LYY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1789224:BFG52 RS01765
gene id: 1789224:BFG52_RS01765
uniprot id: A0A1B2LWQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1789224:BFG52 RS09975
gene id: 1789224:BFG52_RS09975
uniprot id: A0A1B2M0C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1789224:BFG52 RS10780
gene id: 1789224:BFG52_RS10780
uniprot id: A0A1B2M0Q5
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS09205
gene id: 1789224:BFG52_RS09205
uniprot id: A0A1B2LZZ8
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS12585
gene id: 1789224:BFG52_RS12585
uniprot id: A0A1B2M1N0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1789224:BFG52 RS11260
gene id: 1789224:BFG52_RS11260
uniprot id: A0A1B2M119
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS04365
gene id: 1789224:BFG52_RS04365
uniprot id: A0A1B2M3V4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1789224:BFG52 RS04000
gene id: 1789224:BFG52_RS04000
uniprot id: A0A1B2LXC4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1789224:BFG52 RS00975
gene id: 1789224:BFG52_RS00975
uniprot id: A0A1B2LWC1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1789224:BFG52 RS08725
gene id: 1789224:BFG52_RS08725
uniprot id: A0A1B2LZQ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1789224:BFG52 RS13680
gene id: 1789224:BFG52_RS13680
uniprot id: A0A1B2M2C1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS15265
gene id: 1789224:BFG52_RS15265
uniprot id: A0A1B2M313
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1789224:BFG52 RS14855
gene id: 1789224:BFG52_RS14855
uniprot id: A0A1B2M2T6
names: Similarity
messages: Belongs to the SsuE family.

1789224:BFG52 RS03090
gene id: 1789224:BFG52_RS03090
uniprot id: A0A1B2LWW5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1789224:BFG52 RS13475
gene id: 1789224:BFG52_RS13475
uniprot id: A0A1B2M250
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1789224:BFG52 RS02760
gene id: 1789224:BFG52_RS02760
uniprot id: A0A1B2LWR4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS16490
gene id: 1789224:BFG52_RS16490
uniprot id: A0A1B2M3L6
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS01580
gene id: 1789224:BFG52_RS01580
uniprot id: A0A1B2LW53
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1789224:BFG52 RS16295
gene id: 1789224:BFG52_RS16295
uniprot id: A0A1B2M3J9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS01920
gene id: 1789224:BFG52_RS01920
uniprot id: A0A1B2LWA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1789224:BFG52 RS09795
gene id: 1789224:BFG52_RS09795
uniprot id: A0A1B2M085
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1789224:BFG52 RS04330
gene id: 1789224:BFG52_RS04330
uniprot id: A0A1B2LXP5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS00220
gene id: 1789224:BFG52_RS00220
uniprot id: A0A1B2LVI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1789224:BFG52 RS02145
gene id: 1789224:BFG52_RS02145
uniprot id: A0A1B2LWH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1789224:BFG52 RS13360
gene id: 1789224:BFG52_RS13360
uniprot id: A0A1B2M226
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1789224:BFG52 RS06130
gene id: 1789224:BFG52_RS06130
uniprot id: A0A1B2LYE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1789224:BFG52 RS06735
gene id: 1789224:BFG52_RS06735
uniprot id: A0A1B2LYQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1789224:BFG52 RS15825
gene id: 1789224:BFG52_RS15825
uniprot id: A0A1B2M3B1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1789224:BFG52 RS12190
gene id: 1789224:BFG52_RS12190
uniprot id: A0A1B2M1G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1789224:BFG52 RS03145
gene id: 1789224:BFG52_RS03145
uniprot id: A0A1B2LWY0
names: Similarity
messages: Belongs to the fabD family.

1789224:BFG52 RS03150
gene id: 1789224:BFG52_RS03150
uniprot id: A0A1B2LWY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1789224:BFG52 RS14340
gene id: 1789224:BFG52_RS14340
uniprot id: A0A1B2M2J8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1789224:BFG52 RS11775
gene id: 1789224:BFG52_RS11775
uniprot id: A0A1B2M1D0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1789224:BFG52 RS15165
gene id: 1789224:BFG52_RS15165
uniprot id: A0A1B2M342
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1789224:BFG52 RS01700
gene id: 1789224:BFG52_RS01700
uniprot id: A0A1B2LW71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1789224:BFG52 RS08545
gene id: 1789224:BFG52_RS08545
uniprot id: A0A1B2LZM7
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS02350
gene id: 1789224:BFG52_RS02350
uniprot id: A0A1B2LWI6
names: Similarity
messages: Belongs to the BolA/IbaG family.

1789224:BFG52 RS16250
gene id: 1789224:BFG52_RS16250
uniprot id: A0A1B2M3G6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1789224:BFG52 RS01190
gene id: 1789224:BFG52_RS01190
uniprot id: A0A1B2LW22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1789224:BFG52 RS14945
gene id: 1789224:BFG52_RS14945
uniprot id: A0A1B2M2U3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1789224:BFG52 RS13025
gene id: 1789224:BFG52_RS13025
uniprot id: A0A1B2M1W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1789224:BFG52 RS04345
gene id: 1789224:BFG52_RS04345
uniprot id: A0A1B2LXH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1789224:BFG52 RS15715
gene id: 1789224:BFG52_RS15715
uniprot id: A0A1B2M3D8
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1789224:BFG52 RS05065
gene id: 1789224:BFG52_RS05065
uniprot id: A0A1B2LXX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1789224:BFG52 RS06955
gene id: 1789224:BFG52_RS06955
uniprot id: A0A1B2LYW0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS12920
gene id: 1789224:BFG52_RS12920
uniprot id: A0A1B2M1U2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS08630
gene id: 1789224:BFG52_RS08630
uniprot id: A0A1B2M047
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS04475
gene id: 1789224:BFG52_RS04475
uniprot id: A0A1B2LXL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1789224:BFG52 RS15950
gene id: 1789224:BFG52_RS15950
uniprot id: A0A1B2M3B6
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS13535
gene id: 1789224:BFG52_RS13535
uniprot id: A0A1B2M258
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1789224:BFG52 RS00960
gene id: 1789224:BFG52_RS00960
uniprot id: A0A1B2LVU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS08445
gene id: 1789224:BFG52_RS08445
uniprot id: A0A1B2LZK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1789224:BFG52 RS06965
gene id: 1789224:BFG52_RS06965
uniprot id: A0A1B2LYT6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1789224:BFG52 RS06615
gene id: 1789224:BFG52_RS06615
uniprot id: A0A1B2LYP7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1789224:BFG52 RS15945
gene id: 1789224:BFG52_RS15945
uniprot id: A0A1B2M3E1
names: Similarity
messages: Belongs to the LOG family.

1789224:BFG52 RS02155
gene id: 1789224:BFG52_RS02155
uniprot id: A0A1B2LWF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1789224:BFG52 RS15155
gene id: 1789224:BFG52_RS15155
uniprot id: A0A1B2M492
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1789224:BFG52 RS04945
gene id: 1789224:BFG52_RS04945
uniprot id: A0A1B2LXU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1789224:BFG52 RS15785
gene id: 1789224:BFG52_RS15785
uniprot id: A0A1B2M387
names: Similarity
messages: Belongs to the ArsC family.

1789224:BFG52 RS08810
gene id: 1789224:BFG52_RS08810
uniprot id: A0A1B2M078
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1789224:BFG52 RS15815
gene id: 1789224:BFG52_RS15815
uniprot id: A0A1B2M3F7
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

1789224:BFG52 RS06255
gene id: 1789224:BFG52_RS06255
uniprot id: A0A1B2LYG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1789224:BFG52 RS04515
gene id: 1789224:BFG52_RS04515
uniprot id: A0A1B2LXP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS08955
gene id: 1789224:BFG52_RS08955
uniprot id: A0A1B2LZV2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS15200
gene id: 1789224:BFG52_RS15200
uniprot id: A0A1B2M2Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1789224:BFG52 RS14415
gene id: 1789224:BFG52_RS14415
uniprot id: A0A1B2M2J7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1789224:BFG52 RS13540
gene id: 1789224:BFG52_RS13540
uniprot id: A0A1B2M249
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS00165
gene id: 1789224:BFG52_RS00165
uniprot id: A0A1B2LVH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1789224:BFG52 RS05030
gene id: 1789224:BFG52_RS05030
uniprot id: A0A1B2LXV2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1789224:BFG52 RS16100
gene id: 1789224:BFG52_RS16100
uniprot id: A0A1B2M3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1789224:BFG52 RS02080
gene id: 1789224:BFG52_RS02080
uniprot id: A0A1B2LWE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1789224:BFG52 RS02275
gene id: 1789224:BFG52_RS02275
uniprot id: A0A1B2LWI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1789224:BFG52 RS02035
gene id: 1789224:BFG52_RS02035
uniprot id: A0A1B2LWV2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1789224:BFG52 RS14100
gene id: 1789224:BFG52_RS14100
uniprot id: A0A1B2M2E9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1789224:BFG52 RS06060
gene id: 1789224:BFG52_RS06060
uniprot id: A0A1B2LYU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1789224:BFG52 RS08495
gene id: 1789224:BFG52_RS08495
uniprot id: A0A1B2LZQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS12710
gene id: 1789224:BFG52_RS12710
uniprot id: A0A1B2M1T9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS12835
gene id: 1789224:BFG52_RS12835
uniprot id: A0A1B2M1V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1789224:BFG52 RS11575
gene id: 1789224:BFG52_RS11575
uniprot id: A0A1B2M167
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1789224:BFG52 RS16360
gene id: 1789224:BFG52_RS16360
uniprot id: A0A1B2M3I5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS01735
gene id: 1789224:BFG52_RS01735
uniprot id: A0A1B2LW89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1789224:BFG52 RS09175
gene id: 1789224:BFG52_RS09175
uniprot id: A0A1B2LZY4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS12780
gene id: 1789224:BFG52_RS12780
uniprot id: A0A1B2M1S4
names: Similarity
messages: Belongs to the MlaA family.

1789224:BFG52 RS15400
gene id: 1789224:BFG52_RS15400
uniprot id: A0A1B2M344
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

1789224:BFG52 RS10435
gene id: 1789224:BFG52_RS10435
uniprot id: A0A1B2M0J9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS05765
gene id: 1789224:BFG52_RS05765
uniprot id: A0A1B2LYA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1789224:BFG52 RS03695
gene id: 1789224:BFG52_RS03695
uniprot id: A0A1B2LX72
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1789224:BFG52 RS08770
gene id: 1789224:BFG52_RS08770
uniprot id: A0A1B2LZR5
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1789224:BFG52 RS02735
gene id: 1789224:BFG52_RS02735
uniprot id: A0A1B2LWR6
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS05375
gene id: 1789224:BFG52_RS05375
uniprot id: A0A1B2LY11
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1789224:BFG52 RS11240
gene id: 1789224:BFG52_RS11240
uniprot id: A0A1B2M0Z3
names: Similarity
messages: Belongs to the pirin family.

1789224:BFG52 RS02075
gene id: 1789224:BFG52_RS02075
uniprot id: A0A1B2LWC8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1789224:BFG52 RS12210
gene id: 1789224:BFG52_RS12210
uniprot id: A0A1B2M1F8
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

1789224:BFG52 RS06095
gene id: 1789224:BFG52_RS06095
uniprot id: A0A1B2LYE3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1789224:BFG52 RS03330
gene id: 1789224:BFG52_RS03330
uniprot id: A0A1B2LX56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1789224:BFG52 RS05225
gene id: 1789224:BFG52_RS05225
uniprot id: A0A1B2LXZ8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1789224:BFG52 RS12895
gene id: 1789224:BFG52_RS12895
uniprot id: A0A1B2M1W2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1789224:BFG52 RS13665
gene id: 1789224:BFG52_RS13665
uniprot id: A0A1B2M284
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1789224:BFG52 RS12300
gene id: 1789224:BFG52_RS12300
uniprot id: A0A1B2M203
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1789224:BFG52 RS16465
gene id: 1789224:BFG52_RS16465
uniprot id: A0A1B2M3K7
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS00435
gene id: 1789224:BFG52_RS00435
uniprot id: A0A1B2LVK1
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1789224:BFG52 RS14790
gene id: 1789224:BFG52_RS14790
uniprot id: A0A1B2M2S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1789224:BFG52 RS03615
gene id: 1789224:BFG52_RS03615
uniprot id: A0A1B2LXB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1789224:BFG52 RS10515
gene id: 1789224:BFG52_RS10515
uniprot id: A0A1B2M147
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1789224:BFG52 RS16375
gene id: 1789224:BFG52_RS16375
uniprot id: A0A1B2M3J7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1789224:BFG52 RS14830
gene id: 1789224:BFG52_RS14830
uniprot id: A0A1B2M2T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1789224:BFG52 RS14395
gene id: 1789224:BFG52_RS14395
uniprot id: A0A1B2M2K9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1789224:BFG52 RS02845
gene id: 1789224:BFG52_RS02845
uniprot id: A0A1B2LWR8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS01315
gene id: 1789224:BFG52_RS01315
uniprot id: A0A1B2LVY2
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1789224:BFG52 RS14430
gene id: 1789224:BFG52_RS14430
uniprot id: A0A1B2M2M4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1789224:BFG52 RS09155
gene id: 1789224:BFG52_RS09155
uniprot id: A0A1B2M007
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1789224:BFG52 RS13520
gene id: 1789224:BFG52_RS13520
uniprot id: A0A1B2M292
names: Similarity
messages: Belongs to the YciI family.

1789224:BFG52 RS01780
gene id: 1789224:BFG52_RS01780
uniprot id: A0A1B2LW74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS04595
gene id: 1789224:BFG52_RS04595
uniprot id: A0A1B2LXP3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1789224:BFG52 RS11365
gene id: 1789224:BFG52_RS11365
uniprot id: A0A1B2M115
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1789224:BFG52 RS02455
gene id: 1789224:BFG52_RS02455
uniprot id: A0A1B2LWK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1789224:BFG52 RS02235
gene id: 1789224:BFG52_RS02235
uniprot id: A0A1B2LWG2
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS01785
gene id: 1789224:BFG52_RS01785
uniprot id: A0A1B2LW98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1789224:BFG52 RS06505
gene id: 1789224:BFG52_RS06505
uniprot id: A0A1B2LYN0
names: Similarity
messages: Belongs to the HIBADH-related family.

1789224:BFG52 RS04460
gene id: 1789224:BFG52_RS04460
uniprot id: A0A1B2LXK8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1789224:BFG52 RS09190
gene id: 1789224:BFG52_RS09190
uniprot id: A0A1B2LZZ4
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1789224:BFG52 RS12815
gene id: 1789224:BFG52_RS12815
uniprot id: A0A1B2M1S3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1789224:BFG52 RS04275
gene id: 1789224:BFG52_RS04275
uniprot id: A0A1B2LXH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1789224:BFG52 RS09610
gene id: 1789224:BFG52_RS09610
uniprot id: A0A1B2M0N3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1789224:BFG52 RS13485
gene id: 1789224:BFG52_RS13485
uniprot id: A0A1B2M247
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1789224:BFG52 RS14555
gene id: 1789224:BFG52_RS14555
uniprot id: A0A1B2M2P9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS10335
gene id: 1789224:BFG52_RS10335
uniprot id: A0A1B2M0L9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS09820
gene id: 1789224:BFG52_RS09820
uniprot id: A0A1B2M0C5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS08565
gene id: 1789224:BFG52_RS08565
uniprot id: A0A1B2LZM9
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS03600
gene id: 1789224:BFG52_RS03600
uniprot id: A0A1B2LX63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1789224:BFG52 RS06530
gene id: 1789224:BFG52_RS06530
uniprot id: A0A1B2M3X1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1789224:BFG52 RS11255
gene id: 1789224:BFG52_RS11255
uniprot id: A0A1B2M0Z2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1789224:BFG52 RS05165
gene id: 1789224:BFG52_RS05165
uniprot id: A0A1B2LXY0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1789224:BFG52 RS03060
gene id: 1789224:BFG52_RS03060
uniprot id: A0A1B2LWU8
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1789224:BFG52 RS12030
gene id: 1789224:BFG52_RS12030
uniprot id: A0A1B2M1C9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1789224:BFG52 RS09165
gene id: 1789224:BFG52_RS09165
uniprot id: A0A1B2M012
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1789224:BFG52 RS05275
gene id: 1789224:BFG52_RS05275
uniprot id: A0A1B2LY03
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

1789224:BFG52 RS11340
gene id: 1789224:BFG52_RS11340
uniprot id: A0A1B2M129
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1789224:BFG52 RS01560
gene id: 1789224:BFG52_RS01560
uniprot id: A0A1B2LW40
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1789224:BFG52 RS03525
gene id: 1789224:BFG52_RS03525
uniprot id: A0A1B2LX48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1789224:BFG52 RS13500
gene id: 1789224:BFG52_RS13500
uniprot id: A0A1B2M248
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS14570
gene id: 1789224:BFG52_RS14570
uniprot id: A0A1B2M2N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1789224:BFG52 RS15050
gene id: 1789224:BFG52_RS15050
uniprot id: A0A1B2M2W4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1789224:BFG52 RS14275
gene id: 1789224:BFG52_RS14275
uniprot id: A0A1B2M2J3
names: Similarity
messages: Belongs to the WrbA family.

1789224:BFG52 RS02670
gene id: 1789224:BFG52_RS02670
uniprot id: A0A1B2LWP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1789224:BFG52 RS05035
gene id: 1789224:BFG52_RS05035
uniprot id: A0A1B2LY22
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1789224:BFG52 RS14110
gene id: 1789224:BFG52_RS14110
uniprot id: A0A1B2M2E8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1789224:BFG52 RS06340
gene id: 1789224:BFG52_RS06340
uniprot id: A0A1B2LYK3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1789224:BFG52 RS01890
gene id: 1789224:BFG52_RS01890
uniprot id: A0A1B2LW97
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1789224:BFG52 RS16975
gene id: 1789224:BFG52_RS16975
uniprot id: A0A1B2LY54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1789224:BFG52 RS04745
gene id: 1789224:BFG52_RS04745
uniprot id: A0A1B2LXR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1789224:BFG52 RS02125
gene id: 1789224:BFG52_RS02125
uniprot id: A0A1B2LWD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1789224:BFG52 RS01195
gene id: 1789224:BFG52_RS01195
uniprot id: A0A1B2LVY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1789224:BFG52 RS09195
gene id: 1789224:BFG52_RS09195
uniprot id: A0A1B2LZZ1
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS06800
gene id: 1789224:BFG52_RS06800
uniprot id: A0A1B2LYW8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS15670
gene id: 1789224:BFG52_RS15670
uniprot id: A0A1B2M383
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS04980
gene id: 1789224:BFG52_RS04980
uniprot id: A0A1B2LYB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1789224:BFG52 RS00140
gene id: 1789224:BFG52_RS00140
uniprot id: A0A1B2M3L3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1789224:BFG52 RS12170
gene id: 1789224:BFG52_RS12170
uniprot id: A0A1B2M1I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1789224:BFG52 RS03040
gene id: 1789224:BFG52_RS03040
uniprot id: A0A1B2LWV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1789224:BFG52 RS11595
gene id: 1789224:BFG52_RS11595
uniprot id: A0A1B2M194
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS13020
gene id: 1789224:BFG52_RS13020
uniprot id: A0A1B2M2D5
names: Similarity
messages: Belongs to the hyi family.

1789224:BFG52 RS05140
gene id: 1789224:BFG52_RS05140
uniprot id: A0A1B2LXZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1789224:BFG52 RS17200
gene id: 1789224:BFG52_RS17200
uniprot id: A0A1B2LYM6
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

1789224:BFG52 RS01185
gene id: 1789224:BFG52_RS01185
uniprot id: A0A1B2LVY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1789224:BFG52 RS00530
gene id: 1789224:BFG52_RS00530
uniprot id: A0A1B2LVN0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1789224:BFG52 RS15525
gene id: 1789224:BFG52_RS15525
uniprot id: A0A1B2M340
names: Similarity
messages: Belongs to the peptidase S11 family.

1789224:BFG52 RS05100
gene id: 1789224:BFG52_RS05100
uniprot id: A0A1B2LY31
names: Similarity
messages: Belongs to the citrate synthase family.

1789224:BFG52 RS11400
gene id: 1789224:BFG52_RS11400
uniprot id: A0A1B2M155
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1789224:BFG52 RS02775
gene id: 1789224:BFG52_RS02775
uniprot id: A0A1B2LWX4
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS11845
gene id: 1789224:BFG52_RS11845
uniprot id: A0A1B2M1S6
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1789224:BFG52 RS03155
gene id: 1789224:BFG52_RS03155
uniprot id: A0A1B2LWX8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1789224:BFG52 RS06770
gene id: 1789224:BFG52_RS06770
uniprot id: A0A1B2LYR1
names: Similarity
messages: Belongs to the allantoicase family.

1789224:BFG52 RS13705
gene id: 1789224:BFG52_RS13705
uniprot id: A0A1B2M281
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1789224:BFG52 RS01300
gene id: 1789224:BFG52_RS01300
uniprot id: A0A1B2LW00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1789224:BFG52 RS00510
gene id: 1789224:BFG52_RS00510
uniprot id: A0A1B2LVN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1789224:BFG52 RS06985
gene id: 1789224:BFG52_RS06985
uniprot id: A0A1B2LYT4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS09225
gene id: 1789224:BFG52_RS09225
uniprot id: A0A1B2LZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS00710
gene id: 1789224:BFG52_RS00710
uniprot id: A0A1B2LVP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1789224:BFG52 RS00590
gene id: 1789224:BFG52_RS00590
uniprot id: A0A1B2LVM7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1789224:BFG52 RS10940
gene id: 1789224:BFG52_RS10940
uniprot id: A0A1B2M1B8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1789224:BFG52 RS12430
gene id: 1789224:BFG52_RS12430
uniprot id: A0A1B2M1J9
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS12480
gene id: 1789224:BFG52_RS12480
uniprot id: A0A1B2M1L4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS02180
gene id: 1789224:BFG52_RS02180
uniprot id: A0A1B2LWG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1789224:BFG52 RS15365
gene id: 1789224:BFG52_RS15365
uniprot id: A0A1B2M316
names: Similarity
messages: Belongs to the VgrG protein family.

1789224:BFG52 RS03430
gene id: 1789224:BFG52_RS03430
uniprot id: A0A1B2LX33
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS04755
gene id: 1789224:BFG52_RS04755
uniprot id: A0A1B2LXS3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1789224:BFG52 RS06150
gene id: 1789224:BFG52_RS06150
uniprot id: A0A1B2LYF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1789224:BFG52 RS08825
gene id: 1789224:BFG52_RS08825
uniprot id: A0A1B2LZS1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1789224:BFG52 RS14785
gene id: 1789224:BFG52_RS14785
uniprot id: A0A1B2M2R2
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

1789224:BFG52 RS03135
gene id: 1789224:BFG52_RS03135
uniprot id: A0A1B2LWY6
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1789224:BFG52 RS01965
gene id: 1789224:BFG52_RS01965
uniprot id: A0A1B2LWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1789224:BFG52 RS09720
gene id: 1789224:BFG52_RS09720
uniprot id: A0A1B2M080
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1789224:BFG52 RS02695
gene id: 1789224:BFG52_RS02695
uniprot id: A0A1B2LX66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1789224:BFG52 RS08360
gene id: 1789224:BFG52_RS08360
uniprot id: A0A1B2M3Z6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS00215
gene id: 1789224:BFG52_RS00215
uniprot id: A0A1B2LVJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1789224:BFG52 RS13170
gene id: 1789224:BFG52_RS13170
uniprot id: A0A1B2M2G5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1789224:BFG52 RS16210
gene id: 1789224:BFG52_RS16210
uniprot id: A0A1B2M3G5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1789224:BFG52 RS13855
gene id: 1789224:BFG52_RS13855
uniprot id: A0A1B2M2B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1789224:BFG52 RS04505
gene id: 1789224:BFG52_RS04505
uniprot id: A0A1B2LY44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1789224:BFG52 RS09680
gene id: 1789224:BFG52_RS09680
uniprot id: A0A1B2M068
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1789224:BFG52 RS02710
gene id: 1789224:BFG52_RS02710
uniprot id: A0A1B2LWQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1789224:BFG52 RS15590
gene id: 1789224:BFG52_RS15590
uniprot id: A0A1B2M371
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1789224:BFG52 RS09295
gene id: 1789224:BFG52_RS09295
uniprot id: A0A1B2M0H2
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS16505
gene id: 1789224:BFG52_RS16505
uniprot id: A0A1B2M4E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1789224:BFG52 RS02190
gene id: 1789224:BFG52_RS02190
uniprot id: A0A1B2LWY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1789224:BFG52 RS06195
gene id: 1789224:BFG52_RS06195
uniprot id: A0A1B2LYL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1789224:BFG52 RS06670
gene id: 1789224:BFG52_RS06670
uniprot id: A0A1B2LYP1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1789224:BFG52 RS06330
gene id: 1789224:BFG52_RS06330
uniprot id: A0A1B2LYI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1789224:BFG52 RS04570
gene id: 1789224:BFG52_RS04570
uniprot id: A0A1B2LXN2
names: Similarity
messages: Belongs to the PrpF family.

1789224:BFG52 RS12140
gene id: 1789224:BFG52_RS12140
uniprot id: A0A1B2M1E8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1789224:BFG52 RS06225
gene id: 1789224:BFG52_RS06225
uniprot id: A0A1B2LYG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1789224:BFG52 RS06365
gene id: 1789224:BFG52_RS06365
uniprot id: A0A1B2LYK4
names: Similarity
messages: Belongs to the glutamate synthase family.

1789224:BFG52 RS10565
gene id: 1789224:BFG52_RS10565
uniprot id: A0A1B2M0M7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1789224:BFG52 RS04485
gene id: 1789224:BFG52_RS04485
uniprot id: A0A1B2LXS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1789224:BFG52 RS06755
gene id: 1789224:BFG52_RS06755
uniprot id: A0A1B2LYS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1789224:BFG52 RS04020
gene id: 1789224:BFG52_RS04020
uniprot id: A0A1B2LXB3
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1789224:BFG52 RS15020
gene id: 1789224:BFG52_RS15020
uniprot id: A0A1B2M2X3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1789224:BFG52 RS12860
gene id: 1789224:BFG52_RS12860
uniprot id: A0A1B2M2A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1789224:BFG52 RS06185
gene id: 1789224:BFG52_RS06185
uniprot id: A0A1B2LYF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

1789224:BFG52 RS14375
gene id: 1789224:BFG52_RS14375
uniprot id: A0A1B2M2J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1789224:BFG52 RS02665
gene id: 1789224:BFG52_RS02665
uniprot id: A0A1B2LWQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1789224:BFG52 RS03675
gene id: 1789224:BFG52_RS03675
uniprot id: A0A1B2LX79
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1789224:BFG52 RS06765
gene id: 1789224:BFG52_RS06765
uniprot id: A0A1B2LZ84
names: Similarity
messages: Belongs to the FAD-dependent urate hydroxylase family.

1789224:BFG52 RS01755
gene id: 1789224:BFG52_RS01755
uniprot id: A0A1B2LW84
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1789224:BFG52 RS00390
gene id: 1789224:BFG52_RS00390
uniprot id: A0A1B2LVM9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1789224:BFG52 RS11745
gene id: 1789224:BFG52_RS11745
uniprot id: A0A1B2M1A2
names: Similarity
messages: Belongs to the peptidase S24 family.

1789224:BFG52 RS01750
gene id: 1789224:BFG52_RS01750
uniprot id: A0A1B2LW77
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS15540
gene id: 1789224:BFG52_RS15540
uniprot id: A0A1B2M362
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1789224:BFG52 RS04655
gene id: 1789224:BFG52_RS04655
uniprot id: A0A1B2LXQ4
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS07895
gene id: 1789224:BFG52_RS07895
uniprot id: A0A1B2LZD8
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1789224:BFG52 RS10495
gene id: 1789224:BFG52_RS10495
uniprot id: A0A1B2M0P1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1789224:BFG52 RS09085
gene id: 1789224:BFG52_RS09085
uniprot id: A0A1B2LZZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1789224:BFG52 RS12750
gene id: 1789224:BFG52_RS12750
uniprot id: A0A1B2M1R0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1789224:BFG52 RS04905
gene id: 1789224:BFG52_RS04905
uniprot id: A0A1B2LXU9
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS01340
gene id: 1789224:BFG52_RS01340
uniprot id: A0A1B2LW13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1789224:BFG52 RS13325
gene id: 1789224:BFG52_RS13325
uniprot id: A0A1B2M227
names: Subcellular Location Annotation
messages: Membrane

1789224:BFG52 RS10065
gene id: 1789224:BFG52_RS10065
uniprot id: A0A1B2M0D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1789224:BFG52 RS14960
gene id: 1789224:BFG52_RS14960
uniprot id: A0A1B2M2V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS04185
gene id: 1789224:BFG52_RS04185
uniprot id: A0A1B2LXE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1789224:BFG52 RS08965
gene id: 1789224:BFG52_RS08965
uniprot id: A0A1B2M471
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1789224:BFG52 RS15600
gene id: 1789224:BFG52_RS15600
uniprot id: A0A1B2M3B9
names: Similarity
messages: Belongs to the P(II) protein family.

1789224:BFG52 RS11770
gene id: 1789224:BFG52_RS11770
uniprot id: A0A1B2M190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1789224:BFG52 RS05650
gene id: 1789224:BFG52_RS05650
uniprot id: A0A1B2LY83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane