1783515:A4E84 RS32610
gene id: 1783515:A4E84_RS32610
uniprot id: A0A143C8R9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS14875
gene id: 1783515:A4E84_RS14875
uniprot id: A0A143BZQ7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1783515:A4E84 RS38460
gene id: 1783515:A4E84_RS38460
uniprot id: A0A143CBN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Vgb family.
messages: Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.
messages: Monomer.

1783515:A4E84 RS16605
gene id: 1783515:A4E84_RS16605
uniprot id: A0A143C0N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1783515:A4E84 RS16615
gene id: 1783515:A4E84_RS16615
uniprot id: A0A143C1D2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1783515:A4E84 RS28110
gene id: 1783515:A4E84_RS28110
uniprot id: A0A143C697
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1783515:A4E84 RS12615
gene id: 1783515:A4E84_RS12615
uniprot id: A0A143BYP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS07195
gene id: 1783515:A4E84_RS07195
uniprot id: A0A143BVL6
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1783515:A4E84 RS11785
gene id: 1783515:A4E84_RS11785
uniprot id: A0A143CE68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1783515:A4E84 RS39355
gene id: 1783515:A4E84_RS39355
uniprot id: A0A143CC30
names: Similarity
messages: Belongs to the GcvT family.

1783515:A4E84 RS07285
gene id: 1783515:A4E84_RS07285
uniprot id: A0A143BWX0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1783515:A4E84 RS16120
gene id: 1783515:A4E84_RS16120
uniprot id: A0A143C0M0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1783515:A4E84 RS09840
gene id: 1783515:A4E84_RS09840
uniprot id: A0A143BX06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1783515:A4E84 RS08385
gene id: 1783515:A4E84_RS08385
uniprot id: A0A143BWK5
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1783515:A4E84 RS34690
gene id: 1783515:A4E84_RS34690
uniprot id: A0A143C9S1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1783515:A4E84 RS27715
gene id: 1783515:A4E84_RS27715
uniprot id: A0A143C692
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS10780
gene id: 1783515:A4E84_RS10780
uniprot id: A0A143BXV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1783515:A4E84 RS25270
gene id: 1783515:A4E84_RS25270
uniprot id: A0A143C548
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1783515:A4E84 RS13160
gene id: 1783515:A4E84_RS13160
uniprot id: A0A143BZK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1783515:A4E84 RS31220
gene id: 1783515:A4E84_RS31220
uniprot id: A0A143C7Z8
names: Similarity
messages: Belongs to the terpene synthase family.

1783515:A4E84 RS24350
gene id: 1783515:A4E84_RS24350
uniprot id: A0A143C4I9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1783515:A4E84 RS15910
gene id: 1783515:A4E84_RS15910
uniprot id: A0A143C0A7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1783515:A4E84 RS02155
gene id: 1783515:A4E84_RS02155
uniprot id: A0A143BTH1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1783515:A4E84 RS02765
gene id: 1783515:A4E84_RS02765
uniprot id: A0A143BTF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS21410
gene id: 1783515:A4E84_RS21410
uniprot id: A0A143C386
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS26780
gene id: 1783515:A4E84_RS26780
uniprot id: A0A143C5R9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS13830
gene id: 1783515:A4E84_RS13830
uniprot id: A0A143C0C3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1783515:A4E84 RS04710
gene id: 1783515:A4E84_RS04710
uniprot id: A0A143BVI5
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

1783515:A4E84 RS35250
gene id: 1783515:A4E84_RS35250
uniprot id: A0A143CA19
names: Similarity
messages: Belongs to the peptidase S8 family.

1783515:A4E84 RS04980
gene id: 1783515:A4E84_RS04980
uniprot id: A0A143BUT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS12530
gene id: 1783515:A4E84_RS12530
uniprot id: A0A143BYG0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS23425
gene id: 1783515:A4E84_RS23425
uniprot id: A0A143CDE0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1783515:A4E84 RS28245
gene id: 1783515:A4E84_RS28245
uniprot id: A0A143C6L9
names: Cofactor
messages: Binds 1 FAD per subunit.

1783515:A4E84 RS28465
gene id: 1783515:A4E84_RS28465
uniprot id: A0A143C7C3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1783515:A4E84 RS04670
gene id: 1783515:A4E84_RS04670
uniprot id: A0A143BUN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS35825
gene id: 1783515:A4E84_RS35825
uniprot id: A0A143CAD8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1783515:A4E84 RS28640
gene id: 1783515:A4E84_RS28640
uniprot id: A0A143C6M3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1783515:A4E84 RS19130
gene id: 1783515:A4E84_RS19130
uniprot id: A0A143C1N9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS13705
gene id: 1783515:A4E84_RS13705
uniprot id: A0A143C0A0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1783515:A4E84 RS03935
gene id: 1783515:A4E84_RS03935
uniprot id: A0A143BUC2
names: Similarity
messages: Belongs to the HypE family.

1783515:A4E84 RS24310
gene id: 1783515:A4E84_RS24310
uniprot id: A0A143C4D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1783515:A4E84 RS14105
gene id: 1783515:A4E84_RS14105
uniprot id: A0A143BZE9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1783515:A4E84 RS25470
gene id: 1783515:A4E84_RS25470
uniprot id: A0A143C5T4
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Cys-Ser-Gly.
messages: Cytoplasm

1783515:A4E84 RS23675
gene id: 1783515:A4E84_RS23675
uniprot id: A0A143C4Y6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1783515:A4E84 RS00915
gene id: 1783515:A4E84_RS00915
uniprot id: A0A143BSW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS23355
gene id: 1783515:A4E84_RS23355
uniprot id: A0A143C438
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS02400
gene id: 1783515:A4E84_RS02400
uniprot id: A0A143BTK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1783515:A4E84 RS34155
gene id: 1783515:A4E84_RS34155
uniprot id: A0A143C9H3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS04645
gene id: 1783515:A4E84_RS04645
uniprot id: A0A143BUE9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS05670
gene id: 1783515:A4E84_RS05670
uniprot id: A0A143BUY1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS06125
gene id: 1783515:A4E84_RS06125
uniprot id: A0A143BWC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1783515:A4E84 RS22405
gene id: 1783515:A4E84_RS22405
uniprot id: A0A143C4X1
names: Similarity
messages: Belongs to the GSP E family.

1783515:A4E84 RS34085
gene id: 1783515:A4E84_RS34085
uniprot id: A0A143C9I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1783515:A4E84 RS27760
gene id: 1783515:A4E84_RS27760
uniprot id: A0A143C679
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

1783515:A4E84 RS25585
gene id: 1783515:A4E84_RS25585
uniprot id: A0A143C556
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1783515:A4E84 RS07155
gene id: 1783515:A4E84_RS07155
uniprot id: A0A143BVY3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1783515:A4E84 RS29465
gene id: 1783515:A4E84_RS29465
uniprot id: A0A143C802
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1783515:A4E84 RS16200
gene id: 1783515:A4E84_RS16200
uniprot id: A0A143C0A9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1783515:A4E84 RS38185
gene id: 1783515:A4E84_RS38185
uniprot id: A0A143CBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS26835
gene id: 1783515:A4E84_RS26835
uniprot id: A0A143C5T0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1783515:A4E84 RS07460
gene id: 1783515:A4E84_RS07460
uniprot id: A0A143BWX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1783515:A4E84 RS02460
gene id: 1783515:A4E84_RS02460
uniprot id: A0A143BTL6
names: Similarity
messages: Belongs to the peptidase S33 family.

1783515:A4E84 RS15725
gene id: 1783515:A4E84_RS15725
uniprot id: A0A143C151
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1783515:A4E84 RS34525
gene id: 1783515:A4E84_RS34525
uniprot id: A0A143CAP1
names: Similarity
messages: Belongs to the DDAH family.

1783515:A4E84 RS02190
gene id: 1783515:A4E84_RS02190
uniprot id: A0A143BT54
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1783515:A4E84 RS39315
gene id: 1783515:A4E84_RS39315
uniprot id: A0A143CE87
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS10240
gene id: 1783515:A4E84_RS10240
uniprot id: A0A143BXG1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS06780
gene id: 1783515:A4E84_RS06780
uniprot id: A0A143BVF2
names: Similarity
messages: Belongs to the UPF0749 family.

1783515:A4E84 RS31120
gene id: 1783515:A4E84_RS31120
uniprot id: A0A143C9B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS33245
gene id: 1783515:A4E84_RS33245
uniprot id: A0A143C925
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1783515:A4E84 RS01285
gene id: 1783515:A4E84_RS01285
uniprot id: A0A143BSR2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS24630
gene id: 1783515:A4E84_RS24630
uniprot id: A0A143C4N9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1783515:A4E84 RS12720
gene id: 1783515:A4E84_RS12720
uniprot id: A0A143BYW7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS13515
gene id: 1783515:A4E84_RS13515
uniprot id: A0A143BZB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1783515:A4E84 RS21865
gene id: 1783515:A4E84_RS21865
uniprot id: A0A143C398
names: Similarity
messages: Belongs to the cytochrome P450 family.

1783515:A4E84 RS24020
gene id: 1783515:A4E84_RS24020
uniprot id: A0A143C550
names: Similarity
messages: Belongs to the UPF0234 family.

1783515:A4E84 RS06130
gene id: 1783515:A4E84_RS06130
uniprot id: A0A143BV71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS16495
gene id: 1783515:A4E84_RS16495
uniprot id: A0A143C0E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1783515:A4E84 RS01715
gene id: 1783515:A4E84_RS01715
uniprot id: A0A143BT98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS13230
gene id: 1783515:A4E84_RS13230
uniprot id: A0A143BZ04
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS30315
gene id: 1783515:A4E84_RS30315
uniprot id: A0A143C7I8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1783515:A4E84 RS07895
gene id: 1783515:A4E84_RS07895
uniprot id: A0A143BWB6
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1783515:A4E84 RS21325
gene id: 1783515:A4E84_RS21325
uniprot id: A0A143C316
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS15940
gene id: 1783515:A4E84_RS15940
uniprot id: A0A143C067
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1783515:A4E84 RS28280
gene id: 1783515:A4E84_RS28280
uniprot id: A0A143C6M4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits.
messages: In the C-terminal section; belongs to the urease beta subunit family.
messages: In the N-terminal section; belongs to the urease gamma subunit family.

1783515:A4E84 RS15295
gene id: 1783515:A4E84_RS15295
uniprot id: A0A143C071
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS17785
gene id: 1783515:A4E84_RS17785
uniprot id: A0A143C1Z0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1783515:A4E84 RS13240
gene id: 1783515:A4E84_RS13240
uniprot id: A0A143C019
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS09135
gene id: 1783515:A4E84_RS09135
uniprot id: A0A143BWX8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS08490
gene id: 1783515:A4E84_RS08490
uniprot id: A0A143BWM2
names: Similarity
messages: Belongs to the peptidase S45 family.

1783515:A4E84 RS14240
gene id: 1783515:A4E84_RS14240
uniprot id: A0A143BZJ7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS03405
gene id: 1783515:A4E84_RS03405
uniprot id: A0A143BTQ4
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1783515:A4E84 RS37640
gene id: 1783515:A4E84_RS37640
uniprot id: A0A143CB79
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1783515:A4E84 RS06795
gene id: 1783515:A4E84_RS06795
uniprot id: A0A143BWE1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1783515:A4E84 RS22675
gene id: 1783515:A4E84_RS22675
uniprot id: A0A143C3M9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1783515:A4E84 RS03085
gene id: 1783515:A4E84_RS03085
uniprot id: A0A143BTY5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1783515:A4E84 RS19540
gene id: 1783515:A4E84_RS19540
uniprot id: A0A143C257
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS13970
gene id: 1783515:A4E84_RS13970
uniprot id: A0A143BZK1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1783515:A4E84 RS36180
gene id: 1783515:A4E84_RS36180
uniprot id: A0A143CAI6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS26685
gene id: 1783515:A4E84_RS26685
uniprot id: A0A143C5P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

1783515:A4E84 RS08210
gene id: 1783515:A4E84_RS08210
uniprot id: A0A143BX60
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1783515:A4E84 RS18205
gene id: 1783515:A4E84_RS18205
uniprot id: A0A143C193
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS27970
gene id: 1783515:A4E84_RS27970
uniprot id: A0A143C6H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS36555
gene id: 1783515:A4E84_RS36555
uniprot id: A0A143CAP9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS02125
gene id: 1783515:A4E84_RS02125
uniprot id: A0A143BT43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1783515:A4E84 RS20090
gene id: 1783515:A4E84_RS20090
uniprot id: A0A143C2J4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1783515:A4E84 RS07715
gene id: 1783515:A4E84_RS07715
uniprot id: A0A143BWX1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1783515:A4E84 RS25185
gene id: 1783515:A4E84_RS25185
uniprot id: A0A143C4S3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS28305
gene id: 1783515:A4E84_RS28305
uniprot id: A0A143C6J5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1783515:A4E84 RS22370
gene id: 1783515:A4E84_RS22370
uniprot id: A0A143C3J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1783515:A4E84 RS15680
gene id: 1783515:A4E84_RS15680
uniprot id: A0A143C0D7
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1783515:A4E84 RS08295
gene id: 1783515:A4E84_RS08295
uniprot id: A0A143BW92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1783515:A4E84 RS28670
gene id: 1783515:A4E84_RS28670
uniprot id: A0A143C7J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1783515:A4E84 RS18075
gene id: 1783515:A4E84_RS18075
uniprot id: A0A143C1F8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1783515:A4E84 RS32615
gene id: 1783515:A4E84_RS32615
uniprot id: A0A143C8S4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS13755
gene id: 1783515:A4E84_RS13755
uniprot id: A0A143BZ86
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS11230
gene id: 1783515:A4E84_RS11230
uniprot id: A0A143BZ11
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1783515:A4E84 RS08750
gene id: 1783515:A4E84_RS08750
uniprot id: A0A143BWG2
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1783515:A4E84 RS26385
gene id: 1783515:A4E84_RS26385
uniprot id: A0A143C687
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1783515:A4E84 RS33535
gene id: 1783515:A4E84_RS33535
uniprot id: A0A143CDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS32600
gene id: 1783515:A4E84_RS32600
uniprot id: A0A143C8T2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS21800
gene id: 1783515:A4E84_RS21800
uniprot id: A0A143C3H1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS30975
gene id: 1783515:A4E84_RS30975
uniprot id: A0A143C806
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS08415
gene id: 1783515:A4E84_RS08415
uniprot id: A0A143BWA5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS07915
gene id: 1783515:A4E84_RS07915
uniprot id: A0A143BX74
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS11085
gene id: 1783515:A4E84_RS11085
uniprot id: A0A143BXR8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1783515:A4E84 RS29480
gene id: 1783515:A4E84_RS29480
uniprot id: A0A143C735
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1783515:A4E84 RS22780
gene id: 1783515:A4E84_RS22780
uniprot id: A0A143C3T2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1783515:A4E84 RS12925
gene id: 1783515:A4E84_RS12925
uniprot id: A0A143BYP1
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1783515:A4E84 RS21210
gene id: 1783515:A4E84_RS21210
uniprot id: A0A143C2X1
names: Subcellular Location Annotation
messages: Cytoplasm

1783515:A4E84 RS13350
gene id: 1783515:A4E84_RS13350
uniprot id: A0A143C040
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1783515:A4E84 RS08280
gene id: 1783515:A4E84_RS08280
uniprot id: A0A143BWG5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1783515:A4E84 RS27160
gene id: 1783515:A4E84_RS27160
uniprot id: A0A143C5T2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS16990
gene id: 1783515:A4E84_RS16990
uniprot id: A0A143C0Y8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS22470
gene id: 1783515:A4E84_RS22470
uniprot id: A0A143C3G6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1783515:A4E84 RS17430
gene id: 1783515:A4E84_RS17430
uniprot id: A0A143C0V9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS15890
gene id: 1783515:A4E84_RS15890
uniprot id: A0A143C087
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1783515:A4E84 RS07005
gene id: 1783515:A4E84_RS07005
uniprot id: A0A143BVM7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS03925
gene id: 1783515:A4E84_RS03925
uniprot id: A0A143BUZ0
names: Similarity
messages: Belongs to the HupF/HypC family.

1783515:A4E84 RS37230
gene id: 1783515:A4E84_RS37230
uniprot id: A0A143CC11
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1783515:A4E84 RS02520
gene id: 1783515:A4E84_RS02520
uniprot id: A0A143BTM8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS23780
gene id: 1783515:A4E84_RS23780
uniprot id: A0A143CDF3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS19455
gene id: 1783515:A4E84_RS19455
uniprot id: A0A143C2T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

1783515:A4E84 RS26080
gene id: 1783515:A4E84_RS26080
uniprot id: A0A143C589
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS26980
gene id: 1783515:A4E84_RS26980
uniprot id: A0A143C6K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1783515:A4E84 RS21985
gene id: 1783515:A4E84_RS21985
uniprot id: A0A143CEC5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS37605
gene id: 1783515:A4E84_RS37605
uniprot id: A0A143CBR5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS37160
gene id: 1783515:A4E84_RS37160
uniprot id: A0A143CB32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1783515:A4E84 RS29145
gene id: 1783515:A4E84_RS29145
uniprot id: A0A143C6Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1783515:A4E84 RS30440
gene id: 1783515:A4E84_RS30440
uniprot id: A0A143C897
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS30720
gene id: 1783515:A4E84_RS30720
uniprot id: A0A143C7R9
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1783515:A4E84 RS08175
gene id: 1783515:A4E84_RS08175
uniprot id: A0A143BWE3
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1783515:A4E84 RS34245
gene id: 1783515:A4E84_RS34245
uniprot id: A0A143CA70
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1783515:A4E84 RS38035
gene id: 1783515:A4E84_RS38035
uniprot id: A0A143CBE7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS13380
gene id: 1783515:A4E84_RS13380
uniprot id: A0A143BZP7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1783515:A4E84 RS10485
gene id: 1783515:A4E84_RS10485
uniprot id: A0A143BXG8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS23990
gene id: 1783515:A4E84_RS23990
uniprot id: A0A143C4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1783515:A4E84 RS22395
gene id: 1783515:A4E84_RS22395
uniprot id: A0A143C3H7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1783515:A4E84 RS27395
gene id: 1783515:A4E84_RS27395
uniprot id: A0A143C7E9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS07705
gene id: 1783515:A4E84_RS07705
uniprot id: A0A143BVW5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1783515:A4E84 RS22685
gene id: 1783515:A4E84_RS22685
uniprot id: A0A143C517
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1783515:A4E84 RS05950
gene id: 1783515:A4E84_RS05950
uniprot id: A0A143BVC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1783515:A4E84 RS03120
gene id: 1783515:A4E84_RS03120
uniprot id: A0A143CCG3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS37285
gene id: 1783515:A4E84_RS37285
uniprot id: A0A143CC22
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS34240
gene id: 1783515:A4E84_RS34240
uniprot id: A0A143C9P7
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1783515:A4E84 RS17790
gene id: 1783515:A4E84_RS17790
uniprot id: A0A143C1F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS23060
gene id: 1783515:A4E84_RS23060
uniprot id: A0A143C440
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1783515:A4E84 RS27615
gene id: 1783515:A4E84_RS27615
uniprot id: A0A143C698
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1783515:A4E84 RS23390
gene id: 1783515:A4E84_RS23390
uniprot id: A0A143C493
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1783515:A4E84 RS21270
gene id: 1783515:A4E84_RS21270
uniprot id: A0A143C475
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1783515:A4E84 RS34200
gene id: 1783515:A4E84_RS34200
uniprot id: A0A143C9K3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1783515:A4E84 RS05610
gene id: 1783515:A4E84_RS05610
uniprot id: A0A143BUW8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS22625
gene id: 1783515:A4E84_RS22625
uniprot id: A0A143C3L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS35295
gene id: 1783515:A4E84_RS35295
uniprot id: A0A143CAP4
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1783515:A4E84 RS28375
gene id: 1783515:A4E84_RS28375
uniprot id: A0A143C6E4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1783515:A4E84 RS18675
gene id: 1783515:A4E84_RS18675
uniprot id: A0A143C1V9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1783515:A4E84 RS28595
gene id: 1783515:A4E84_RS28595
uniprot id: A0A143C841
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1783515:A4E84 RS11220
gene id: 1783515:A4E84_RS11220
uniprot id: A0A143BXZ4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1783515:A4E84 RS05325
gene id: 1783515:A4E84_RS05325
uniprot id: A0A143BVY7
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

1783515:A4E84 RS05935
gene id: 1783515:A4E84_RS05935
uniprot id: A0A143BW64
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS16155
gene id: 1783515:A4E84_RS16155
uniprot id: A0A143C0C0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1783515:A4E84 RS26295
gene id: 1783515:A4E84_RS26295
uniprot id: A0A143C5H4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1783515:A4E84 RS24875
gene id: 1783515:A4E84_RS24875
uniprot id: A0A143C4S6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS32560
gene id: 1783515:A4E84_RS32560
uniprot id: A0A143CA01
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS31285
gene id: 1783515:A4E84_RS31285
uniprot id: A0A143C820
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

1783515:A4E84 RS09355
gene id: 1783515:A4E84_RS09355
uniprot id: A0A143BWS8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1783515:A4E84 RS10410
gene id: 1783515:A4E84_RS10410
uniprot id: A0A143BXL3
names: Similarity
messages: Belongs to the group II decarboxylase family.

1783515:A4E84 RS08165
gene id: 1783515:A4E84_RS08165
uniprot id: A0A143BWG4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1783515:A4E84 RS06875
gene id: 1783515:A4E84_RS06875
uniprot id: A0A143BVS3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1783515:A4E84 RS19445
gene id: 1783515:A4E84_RS19445
uniprot id: A0A143CD80
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS16845
gene id: 1783515:A4E84_RS16845
uniprot id: A0A143C0Z4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1783515:A4E84 RS23095
gene id: 1783515:A4E84_RS23095
uniprot id: A0A143C3S6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1783515:A4E84 RS09910
gene id: 1783515:A4E84_RS09910
uniprot id: A0A143BXA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1783515:A4E84 RS17305
gene id: 1783515:A4E84_RS17305
uniprot id: A0A143C125
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1783515:A4E84 RS31260
gene id: 1783515:A4E84_RS31260
uniprot id: A0A143C853
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1783515:A4E84 RS15625
gene id: 1783515:A4E84_RS15625
uniprot id: A0A143C0C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1783515:A4E84 RS29105
gene id: 1783515:A4E84_RS29105
uniprot id: A0A143C7M9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS36550
gene id: 1783515:A4E84_RS36550
uniprot id: A0A143CAP6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1783515:A4E84 RS21250
gene id: 1783515:A4E84_RS21250
uniprot id: A0A143C362
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS25265
gene id: 1783515:A4E84_RS25265
uniprot id: A0A143C5P5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1783515:A4E84 RS27825
gene id: 1783515:A4E84_RS27825
uniprot id: A0A143C7N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS10590
gene id: 1783515:A4E84_RS10590
uniprot id: A0A143BXH3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1783515:A4E84 RS33830
gene id: 1783515:A4E84_RS33830
uniprot id: A0A143C9E6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS11940
gene id: 1783515:A4E84_RS11940
uniprot id: A0A143BYH3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1783515:A4E84 RS07450
gene id: 1783515:A4E84_RS07450
uniprot id: A0A143BVT2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1783515:A4E84 RS12165
gene id: 1783515:A4E84_RS12165
uniprot id: A0A143BYG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1783515:A4E84 RS08840
gene id: 1783515:A4E84_RS08840
uniprot id: A0A143BWR5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1783515:A4E84 RS27350
gene id: 1783515:A4E84_RS27350
uniprot id: A0A143C5W1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS09975
gene id: 1783515:A4E84_RS09975
uniprot id: A0A143BYB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1783515:A4E84 RS21475
gene id: 1783515:A4E84_RS21475
uniprot id: A0A143C320
names: Similarity
messages: Belongs to the ice-binding protein family.

1783515:A4E84 RS14830
gene id: 1783515:A4E84_RS14830
uniprot id: A0A143C002
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS26005
gene id: 1783515:A4E84_RS26005
uniprot id: A0A143C5C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1783515:A4E84 RS23810
gene id: 1783515:A4E84_RS23810
uniprot id: A0A143C4A9
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1783515:A4E84 RS37685
gene id: 1783515:A4E84_RS37685
uniprot id: A0A143CB91
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1783515:A4E84 RS03225
gene id: 1783515:A4E84_RS03225
uniprot id: A0A143BUN4
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS35685
gene id: 1783515:A4E84_RS35685
uniprot id: A0A143CAE8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS16240
gene id: 1783515:A4E84_RS16240
uniprot id: A0A143C0H8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS18910
gene id: 1783515:A4E84_RS18910
uniprot id: A0A143C2I9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS02030
gene id: 1783515:A4E84_RS02030
uniprot id: A0A143BTE8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS32555
gene id: 1783515:A4E84_RS32555
uniprot id: A0A143C8R4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1783515:A4E84 RS20835
gene id: 1783515:A4E84_RS20835
uniprot id: A0A143C2J6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS12050
gene id: 1783515:A4E84_RS12050
uniprot id: A0A143BYJ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS02965
gene id: 1783515:A4E84_RS02965
uniprot id: A0A143BTV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS26315
gene id: 1783515:A4E84_RS26315
uniprot id: A0A143C5C3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS28535
gene id: 1783515:A4E84_RS28535
uniprot id: A0A143C6P4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1783515:A4E84 RS04190
gene id: 1783515:A4E84_RS04190
uniprot id: A0A143CCN0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1783515:A4E84 RS08000
gene id: 1783515:A4E84_RS08000
uniprot id: A0A143BWD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS34725
gene id: 1783515:A4E84_RS34725
uniprot id: A0A143CAF0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS24815
gene id: 1783515:A4E84_RS24815
uniprot id: A0A143C4L9
names: Similarity
messages: Belongs to the peptidase C40 family.

1783515:A4E84 RS28750
gene id: 1783515:A4E84_RS28750
uniprot id: A0A143C6N1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1783515:A4E84 RS13860
gene id: 1783515:A4E84_RS13860
uniprot id: A0A143BZI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS21575
gene id: 1783515:A4E84_RS21575
uniprot id: A0A143C3V7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS25125
gene id: 1783515:A4E84_RS25125
uniprot id: A0A143C4T2
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1783515:A4E84 RS15290
gene id: 1783515:A4E84_RS15290
uniprot id: A0A143C0L7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS27090
gene id: 1783515:A4E84_RS27090
uniprot id: A0A143C5Y0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1783515:A4E84 RS39745
gene id: 1783515:A4E84_RS39745
uniprot id: A0A143CCC0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS33790
gene id: 1783515:A4E84_RS33790
uniprot id: A0A143C9D4
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1783515:A4E84 RS38070
gene id: 1783515:A4E84_RS38070
uniprot id: A0A143CBF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS18050
gene id: 1783515:A4E84_RS18050
uniprot id: A0A143C2C7
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1783515:A4E84 RS23280
gene id: 1783515:A4E84_RS23280
uniprot id: A0A143C4V6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS18265
gene id: 1783515:A4E84_RS18265
uniprot id: A0A143C1G3
names: Similarity
messages: Belongs to the YciI family.

1783515:A4E84 RS29080
gene id: 1783515:A4E84_RS29080
uniprot id: A0A143C6U1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS20710
gene id: 1783515:A4E84_RS20710
uniprot id: A0A143C2S9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1783515:A4E84 RS37940
gene id: 1783515:A4E84_RS37940
uniprot id: A0A143CBV6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1783515:A4E84 RS03600
gene id: 1783515:A4E84_RS03600
uniprot id: A0A143BU56
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1783515:A4E84 RS07830
gene id: 1783515:A4E84_RS07830
uniprot id: A0A143BWA7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1783515:A4E84 RS38625
gene id: 1783515:A4E84_RS38625
uniprot id: A0A143CBP5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1783515:A4E84 RS18410
gene id: 1783515:A4E84_RS18410
uniprot id: A0A143C1M4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS24280
gene id: 1783515:A4E84_RS24280
uniprot id: A0A143C4N5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1783515:A4E84 RS16270
gene id: 1783515:A4E84_RS16270
uniprot id: A0A143CE46
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1783515:A4E84 RS09750
gene id: 1783515:A4E84_RS09750
uniprot id: A0A143BXB9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1783515:A4E84 RS10595
gene id: 1783515:A4E84_RS10595
uniprot id: A0A143BXI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1783515:A4E84 RS03730
gene id: 1783515:A4E84_RS03730
uniprot id: A0A143BTW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS28685
gene id: 1783515:A4E84_RS28685
uniprot id: A0A143C6S2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1783515:A4E84 RS04815
gene id: 1783515:A4E84_RS04815
uniprot id: A0A143BVN1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS25170
gene id: 1783515:A4E84_RS25170
uniprot id: A0A143C4X6
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1783515:A4E84 RS08190
gene id: 1783515:A4E84_RS08190
uniprot id: A0A143BW72
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1783515:A4E84 RS16235
gene id: 1783515:A4E84_RS16235
uniprot id: A0A143C0N6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS34770
gene id: 1783515:A4E84_RS34770
uniprot id: A0A143C9Z9
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

1783515:A4E84 RS25825
gene id: 1783515:A4E84_RS25825
uniprot id: A0A143C597
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS02115
gene id: 1783515:A4E84_RS02115
uniprot id: A0A143BUB7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1783515:A4E84 RS35695
gene id: 1783515:A4E84_RS35695
uniprot id: A0A143CBB8
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS15485
gene id: 1783515:A4E84_RS15485
uniprot id: A0A143BZX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS34530
gene id: 1783515:A4E84_RS34530
uniprot id: A0A143C9P4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1783515:A4E84 RS08855
gene id: 1783515:A4E84_RS08855
uniprot id: A0A143BWJ6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1783515:A4E84 RS29905
gene id: 1783515:A4E84_RS29905
uniprot id: A0A143C7B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1783515:A4E84 RS35915
gene id: 1783515:A4E84_RS35915
uniprot id: A0A143CAD6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS09420
gene id: 1783515:A4E84_RS09420
uniprot id: A0A143BXW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1783515:A4E84 RS13880
gene id: 1783515:A4E84_RS13880
uniprot id: A0A143C0D4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1783515:A4E84 RS34990
gene id: 1783515:A4E84_RS34990
uniprot id: A0A143C9Y1
names: Similarity
messages: Belongs to the Dps family.

1783515:A4E84 RS16335
gene id: 1783515:A4E84_RS16335
uniprot id: A0A143C0I8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS39490
gene id: 1783515:A4E84_RS39490
uniprot id: A0A143CDG3
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1783515:A4E84 RS03275
gene id: 1783515:A4E84_RS03275
uniprot id: A0A143BUV4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS23700
gene id: 1783515:A4E84_RS23700
uniprot id: A0A143C488
names: Similarity
messages: Belongs to the peptidase C40 family.

1783515:A4E84 RS20110
gene id: 1783515:A4E84_RS20110
uniprot id: A0A143C2F6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1783515:A4E84 RS07305
gene id: 1783515:A4E84_RS07305
uniprot id: A0A143BWU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1783515:A4E84 RS27410
gene id: 1783515:A4E84_RS27410
uniprot id: A0A143C658
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1783515:A4E84 RS24420
gene id: 1783515:A4E84_RS24420
uniprot id: A0A143C4K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1783515:A4E84 RS23305
gene id: 1783515:A4E84_RS23305
uniprot id: A0A143C427
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS21585
gene id: 1783515:A4E84_RS21585
uniprot id: A0A143C384
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1783515:A4E84 RS34705
gene id: 1783515:A4E84_RS34705
uniprot id: A0A143CB74
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS07010
gene id: 1783515:A4E84_RS07010
uniprot id: A0A143BVJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1783515:A4E84 RS03240
gene id: 1783515:A4E84_RS03240
uniprot id: A0A143BTZ6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1783515:A4E84 RS24405
gene id: 1783515:A4E84_RS24405
uniprot id: A0A143C5V9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS14645
gene id: 1783515:A4E84_RS14645
uniprot id: A0A143C0Q8
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1783515:A4E84 RS23980
gene id: 1783515:A4E84_RS23980
uniprot id: A0A143C4E4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS28680
gene id: 1783515:A4E84_RS28680
uniprot id: A0A143C6R0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

1783515:A4E84 RS21645
gene id: 1783515:A4E84_RS21645
uniprot id: A0A143C348
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS37985
gene id: 1783515:A4E84_RS37985
uniprot id: A0A143CE70
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1783515:A4E84 RS09495
gene id: 1783515:A4E84_RS09495
uniprot id: A0A143BX25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

1783515:A4E84 RS35515
gene id: 1783515:A4E84_RS35515
uniprot id: A0A143CAT6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS01600
gene id: 1783515:A4E84_RS01600
uniprot id: A0A143BT77
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1783515:A4E84 RS20070
gene id: 1783515:A4E84_RS20070
uniprot id: A0A143C277
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1783515:A4E84 RS36455
gene id: 1783515:A4E84_RS36455
uniprot id: A0A143CAM4
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1783515:A4E84 RS10940
gene id: 1783515:A4E84_RS10940
uniprot id: A0A143BXY3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1783515:A4E84 RS24890
gene id: 1783515:A4E84_RS24890
uniprot id: A0A143C4Y9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1783515:A4E84 RS04840
gene id: 1783515:A4E84_RS04840
uniprot id: A0A143BVD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1783515:A4E84 RS24385
gene id: 1783515:A4E84_RS24385
uniprot id: A0A143C4Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1783515:A4E84 RS03350
gene id: 1783515:A4E84_RS03350
uniprot id: A0A143BU25
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1783515:A4E84 RS06575
gene id: 1783515:A4E84_RS06575
uniprot id: A0A143BVB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1783515:A4E84 RS28760
gene id: 1783515:A4E84_RS28760
uniprot id: A0A143C6V1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS18380
gene id: 1783515:A4E84_RS18380
uniprot id: A0A143C1H9
names: Similarity
messages: Belongs to the peptidase C40 family.

1783515:A4E84 RS20875
gene id: 1783515:A4E84_RS20875
uniprot id: A0A143C2T7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS26885
gene id: 1783515:A4E84_RS26885
uniprot id: A0A143C5U2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS30080
gene id: 1783515:A4E84_RS30080
uniprot id: A0A143C8T8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS31665
gene id: 1783515:A4E84_RS31665
uniprot id: A0A143C964
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS09935
gene id: 1783515:A4E84_RS09935
uniprot id: A0A143BX47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1783515:A4E84 RS31135
gene id: 1783515:A4E84_RS31135
uniprot id: A0A143C815
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1783515:A4E84 RS18220
gene id: 1783515:A4E84_RS18220
uniprot id: A0A143C2F3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS30590
gene id: 1783515:A4E84_RS30590
uniprot id: A0A143C8C9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1783515:A4E84 RS12660
gene id: 1783515:A4E84_RS12660
uniprot id: A0A143BZC1
names: Similarity
messages: Belongs to the CdaR family.

1783515:A4E84 RS28225
gene id: 1783515:A4E84_RS28225
uniprot id: A0A143C6H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS17645
gene id: 1783515:A4E84_RS17645
uniprot id: A0A143C2B5
names: Similarity
messages: Belongs to the citrate synthase family.

1783515:A4E84 RS12815
gene id: 1783515:A4E84_RS12815
uniprot id: A0A143BYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS18715
gene id: 1783515:A4E84_RS18715
uniprot id: A0A143C2P4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS02860
gene id: 1783515:A4E84_RS02860
uniprot id: A0A143BUQ0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1783515:A4E84 RS02540
gene id: 1783515:A4E84_RS02540
uniprot id: A0A143BTB3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS04620
gene id: 1783515:A4E84_RS04620
uniprot id: A0A143BUM3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1783515:A4E84 RS31275
gene id: 1783515:A4E84_RS31275
uniprot id: A0A143C811
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1783515:A4E84 RS32835
gene id: 1783515:A4E84_RS32835
uniprot id: A0A143C9F5
names: Subcellular Location Annotation
messages: Cell membrane

1783515:A4E84 RS24125
gene id: 1783515:A4E84_RS24125
uniprot id: A0A143C4D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1783515:A4E84 RS22105
gene id: 1783515:A4E84_RS22105
uniprot id: A0A143C383
names: Similarity
messages: Belongs to the TPP enzyme family.

1783515:A4E84 RS20660
gene id: 1783515:A4E84_RS20660
uniprot id: A0A143C2R9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24255
gene id: 1783515:A4E84_RS24255
uniprot id: A0A143C4A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1783515:A4E84 RS37120
gene id: 1783515:A4E84_RS37120
uniprot id: A0A143CAY4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1783515:A4E84 RS22110
gene id: 1783515:A4E84_RS22110
uniprot id: A0A143C3A9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1783515:A4E84 RS32750
gene id: 1783515:A4E84_RS32750
uniprot id: A0A143C8U3
names: Similarity
messages: Belongs to the peptidase S45 family.

1783515:A4E84 RS39035
gene id: 1783515:A4E84_RS39035
uniprot id: A0A143CBY6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1783515:A4E84 RS08545
gene id: 1783515:A4E84_RS08545
uniprot id: A0A143BWN6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS16575
gene id: 1783515:A4E84_RS16575
uniprot id: A0A143C0Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1783515:A4E84 RS09480
gene id: 1783515:A4E84_RS09480
uniprot id: A0A143BXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1783515:A4E84 RS24335
gene id: 1783515:A4E84_RS24335
uniprot id: A0A143C4P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1783515:A4E84 RS20830
gene id: 1783515:A4E84_RS20830
uniprot id: A0A143C3Z8
names: Similarity
messages: Belongs to the peptidase M18 family.

1783515:A4E84 RS22495
gene id: 1783515:A4E84_RS22495
uniprot id: A0A143C3T7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS22490
gene id: 1783515:A4E84_RS22490
uniprot id: A0A143C4D3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS27670
gene id: 1783515:A4E84_RS27670
uniprot id: A0A143C703
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1783515:A4E84 RS29470
gene id: 1783515:A4E84_RS29470
uniprot id: A0A143C786
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1783515:A4E84 RS11035
gene id: 1783515:A4E84_RS11035
uniprot id: A0A143BYT7
names: Similarity
messages: Belongs to the peptidase C40 family.

1783515:A4E84 RS28710
gene id: 1783515:A4E84_RS28710
uniprot id: A0A143C6U3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1783515:A4E84 RS14430
gene id: 1783515:A4E84_RS14430
uniprot id: A0A143C0L4
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1783515:A4E84 RS16815
gene id: 1783515:A4E84_RS16815
uniprot id: A0A143C1W8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1783515:A4E84 RS34100
gene id: 1783515:A4E84_RS34100
uniprot id: A0A143CAW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1783515:A4E84 RS07225
gene id: 1783515:A4E84_RS07225
uniprot id: A0A143BVX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS09640
gene id: 1783515:A4E84_RS09640
uniprot id: A0A143BXU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS32685
gene id: 1783515:A4E84_RS32685
uniprot id: A0A143C8T6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

1783515:A4E84 RS11530
gene id: 1783515:A4E84_RS11530
uniprot id: A0A143BYA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS05485
gene id: 1783515:A4E84_RS05485
uniprot id: A0A143BV25
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS06055
gene id: 1783515:A4E84_RS06055
uniprot id: A0A143BVE4
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1783515:A4E84 RS23770
gene id: 1783515:A4E84_RS23770
uniprot id: A0A143C416
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS07960
gene id: 1783515:A4E84_RS07960
uniprot id: A0A143BWA0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1783515:A4E84 RS07610
gene id: 1783515:A4E84_RS07610
uniprot id: A0A143BX27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1783515:A4E84 RS03595
gene id: 1783515:A4E84_RS03595
uniprot id: A0A143BU60
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS02880
gene id: 1783515:A4E84_RS02880
uniprot id: A0A143BUQ7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS25240
gene id: 1783515:A4E84_RS25240
uniprot id: A0A143C691
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

1783515:A4E84 RS14670
gene id: 1783515:A4E84_RS14670
uniprot id: A0A143C0A5
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1783515:A4E84 RS16675
gene id: 1783515:A4E84_RS16675
uniprot id: A0A143C1E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1783515:A4E84 RS16750
gene id: 1783515:A4E84_RS16750
uniprot id: A0A143C0U5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1783515:A4E84 RS32255
gene id: 1783515:A4E84_RS32255
uniprot id: A0A143C8K4
names: Similarity
messages: Belongs to the IucA/IucC family.

1783515:A4E84 RS09090
gene id: 1783515:A4E84_RS09090
uniprot id: A0A143BWN1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1783515:A4E84 RS23175
gene id: 1783515:A4E84_RS23175
uniprot id: A0A143C458
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1783515:A4E84 RS32665
gene id: 1783515:A4E84_RS32665
uniprot id: A0A143C8T9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS21705
gene id: 1783515:A4E84_RS21705
uniprot id: A0A143C358
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1783515:A4E84 RS15080
gene id: 1783515:A4E84_RS15080
uniprot id: A0A143BZZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1783515:A4E84 RS08260
gene id: 1783515:A4E84_RS08260
uniprot id: A0A143BXB3
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1783515:A4E84 RS20020
gene id: 1783515:A4E84_RS20020
uniprot id: A0A143C267
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1783515:A4E84 RS32965
gene id: 1783515:A4E84_RS32965
uniprot id: A0A143CES0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1783515:A4E84 RS11250
gene id: 1783515:A4E84_RS11250
uniprot id: A0A143BYX5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS15365
gene id: 1783515:A4E84_RS15365
uniprot id: A0A143C042
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS10985
gene id: 1783515:A4E84_RS10985
uniprot id: A0A143BYS8
names: Similarity
messages: Belongs to the arsA ATPase family.

1783515:A4E84 RS19360
gene id: 1783515:A4E84_RS19360
uniprot id: A0A143C357
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1783515:A4E84 RS24130
gene id: 1783515:A4E84_RS24130
uniprot id: A0A143C4F0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1783515:A4E84 RS21065
gene id: 1783515:A4E84_RS21065
uniprot id: A0A143C3U9
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1783515:A4E84 RS02720
gene id: 1783515:A4E84_RS02720
uniprot id: A0A143BUM6
names: Similarity
messages: Belongs to the peptidase S33 family.

1783515:A4E84 RS14710
gene id: 1783515:A4E84_RS14710
uniprot id: A0A143BZM8
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS25395
gene id: 1783515:A4E84_RS25395
uniprot id: A0A143C4W2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1783515:A4E84 RS09060
gene id: 1783515:A4E84_RS09060
uniprot id: A0A143BWY9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1783515:A4E84 RS37790
gene id: 1783515:A4E84_RS37790
uniprot id: A0A143CBA8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1783515:A4E84 RS04495
gene id: 1783515:A4E84_RS04495
uniprot id: A0A143BUJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS08200
gene id: 1783515:A4E84_RS08200
uniprot id: A0A143BW53
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1783515:A4E84 RS06310
gene id: 1783515:A4E84_RS06310
uniprot id: A0A143BW52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1783515:A4E84 RS06705
gene id: 1783515:A4E84_RS06705
uniprot id: A0A143BVP3
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1783515:A4E84 RS36520
gene id: 1783515:A4E84_RS36520
uniprot id: A0A143CAT9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS11585
gene id: 1783515:A4E84_RS11585
uniprot id: A0A143CCY4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1783515:A4E84 RS21710
gene id: 1783515:A4E84_RS21710
uniprot id: A0A143C388
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1783515:A4E84 RS12375
gene id: 1783515:A4E84_RS12375
uniprot id: A0A143BYF1
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1783515:A4E84 RS24115
gene id: 1783515:A4E84_RS24115
uniprot id: A0A143C4G4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS18935
gene id: 1783515:A4E84_RS18935
uniprot id: A0A143C2Z1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1783515:A4E84 RS34545
gene id: 1783515:A4E84_RS34545
uniprot id: A0A143C9R6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS31525
gene id: 1783515:A4E84_RS31525
uniprot id: A0A143C886
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1783515:A4E84 RS35255
gene id: 1783515:A4E84_RS35255
uniprot id: A0A143CA29
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS32770
gene id: 1783515:A4E84_RS32770
uniprot id: A0A143C8V7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1783515:A4E84 RS15310
gene id: 1783515:A4E84_RS15310
uniprot id: A0A143C032
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1783515:A4E84 RS27450
gene id: 1783515:A4E84_RS27450
uniprot id: A0A143C5Z1
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1783515:A4E84 RS10125
gene id: 1783515:A4E84_RS10125
uniprot id: A0A143BXE6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS33745
gene id: 1783515:A4E84_RS33745
uniprot id: A0A143C990
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1783515:A4E84 RS01280
gene id: 1783515:A4E84_RS01280
uniprot id: A0A143CCF5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1783515:A4E84 RS07975
gene id: 1783515:A4E84_RS07975
uniprot id: A0A143BW35
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1783515:A4E84 RS25530
gene id: 1783515:A4E84_RS25530
uniprot id: A0A143CDL5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1783515:A4E84 RS08455
gene id: 1783515:A4E84_RS08455
uniprot id: A0A143BXH4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS35795
gene id: 1783515:A4E84_RS35795
uniprot id: A0A143CAH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

1783515:A4E84 RS11440
gene id: 1783515:A4E84_RS11440
uniprot id: A0A143BY69
names: Similarity
messages: Belongs to the ArsC family.

1783515:A4E84 RS20010
gene id: 1783515:A4E84_RS20010
uniprot id: A0A143C3H8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS05945
gene id: 1783515:A4E84_RS05945
uniprot id: A0A143BVC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1783515:A4E84 RS18785
gene id: 1783515:A4E84_RS18785
uniprot id: A0A143C1Y1
names: Similarity
messages: Belongs to the CsoR family.

1783515:A4E84 RS26365
gene id: 1783515:A4E84_RS26365
uniprot id: A0A143C5D4
names: Similarity
messages: Belongs to the LOG family.

1783515:A4E84 RS35910
gene id: 1783515:A4E84_RS35910
uniprot id: A0A143CBG2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS37170
gene id: 1783515:A4E84_RS37170
uniprot id: A0A143CC02
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS14905
gene id: 1783515:A4E84_RS14905
uniprot id: A0A143BZX0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1783515:A4E84 RS26020
gene id: 1783515:A4E84_RS26020
uniprot id: A0A143C6P9
names: Similarity
messages: Belongs to the FBPase class 2 family.

1783515:A4E84 RS03915
gene id: 1783515:A4E84_RS03915
uniprot id: A0A143BTZ2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1783515:A4E84 RS15705
gene id: 1783515:A4E84_RS15705
uniprot id: A0A143C012
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1783515:A4E84 RS24160
gene id: 1783515:A4E84_RS24160
uniprot id: A0A143C573
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1783515:A4E84 RS11380
gene id: 1783515:A4E84_RS11380
uniprot id: A0A143BY23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1783515:A4E84 RS19320
gene id: 1783515:A4E84_RS19320
uniprot id: A0A143C204
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1783515:A4E84 RS08550
gene id: 1783515:A4E84_RS08550
uniprot id: A0A143BWN3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS33765
gene id: 1783515:A4E84_RS33765
uniprot id: A0A143C9D5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS34010
gene id: 1783515:A4E84_RS34010
uniprot id: A0A143C9K4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1783515:A4E84 RS19920
gene id: 1783515:A4E84_RS19920
uniprot id: A0A143C2A7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1783515:A4E84 RS08025
gene id: 1783515:A4E84_RS08025
uniprot id: A0A143CCU3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS14410
gene id: 1783515:A4E84_RS14410
uniprot id: A0A143BZS1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS10415
gene id: 1783515:A4E84_RS10415
uniprot id: A0A143BYK8
names: Similarity
messages: Belongs to the peptidase M1 family.

1783515:A4E84 RS23660
gene id: 1783515:A4E84_RS23660
uniprot id: A0A143C420
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1783515:A4E84 RS23025
gene id: 1783515:A4E84_RS23025
uniprot id: A0A143C3X2
names: Similarity
messages: Belongs to the histone deacetylase family.

1783515:A4E84 RS26260
gene id: 1783515:A4E84_RS26260
uniprot id: A0A143C5B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS39640
gene id: 1783515:A4E84_RS39640
uniprot id: A0A143CCA2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS08625
gene id: 1783515:A4E84_RS08625
uniprot id: A0A143BWP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS08865
gene id: 1783515:A4E84_RS08865
uniprot id: A0A143BWH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1783515:A4E84 RS31395
gene id: 1783515:A4E84_RS31395
uniprot id: A0A143C862
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS02130
gene id: 1783515:A4E84_RS02130
uniprot id: A0A143BT44
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1783515:A4E84 RS04610
gene id: 1783515:A4E84_RS04610
uniprot id: A0A143BV91
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1783515:A4E84 RS25295
gene id: 1783515:A4E84_RS25295
uniprot id: A0A143C4U0
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1783515:A4E84 RS16820
gene id: 1783515:A4E84_RS16820
uniprot id: A0A143C0K7
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1783515:A4E84 RS14555
gene id: 1783515:A4E84_RS14555
uniprot id: A0A143BZG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1783515:A4E84 RS11130
gene id: 1783515:A4E84_RS11130
uniprot id: A0A143BYZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1783515:A4E84 RS31435
gene id: 1783515:A4E84_RS31435
uniprot id: A0A143C855
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS04650
gene id: 1783515:A4E84_RS04650
uniprot id: A0A143BUB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS23070
gene id: 1783515:A4E84_RS23070
uniprot id: A0A143C3Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1783515:A4E84 RS03720
gene id: 1783515:A4E84_RS03720
uniprot id: A0A143BV48
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS19965
gene id: 1783515:A4E84_RS19965
uniprot id: A0A143C258
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1783515:A4E84 RS24430
gene id: 1783515:A4E84_RS24430
uniprot id: A0A143C5C1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1783515:A4E84 RS06255
gene id: 1783515:A4E84_RS06255
uniprot id: A0A143BWC1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS28095
gene id: 1783515:A4E84_RS28095
uniprot id: A0A143C6G1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1783515:A4E84 RS11635
gene id: 1783515:A4E84_RS11635
uniprot id: A0A143BZ37
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS39325
gene id: 1783515:A4E84_RS39325
uniprot id: A0A143CDD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS34515
gene id: 1783515:A4E84_RS34515
uniprot id: A0A143C9V5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1783515:A4E84 RS00860
gene id: 1783515:A4E84_RS00860
uniprot id: A0A143BSV1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS37395
gene id: 1783515:A4E84_RS37395
uniprot id: A0A143CBN2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS15335
gene id: 1783515:A4E84_RS15335
uniprot id: A0A143C0X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1783515:A4E84 RS27345
gene id: 1783515:A4E84_RS27345
uniprot id: A0A143C7C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1783515:A4E84 RS19325
gene id: 1783515:A4E84_RS19325
uniprot id: A0A143C2Z2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1783515:A4E84 RS27415
gene id: 1783515:A4E84_RS27415
uniprot id: A0A143C6U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1783515:A4E84 RS10730
gene id: 1783515:A4E84_RS10730
uniprot id: A0A143BXR5
names: Similarity
messages: Belongs to the YggT family.

1783515:A4E84 RS07090
gene id: 1783515:A4E84_RS07090
uniprot id: A0A143BWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1783515:A4E84 RS33580
gene id: 1783515:A4E84_RS33580
uniprot id: A0A143CAM8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1783515:A4E84 RS34080
gene id: 1783515:A4E84_RS34080
uniprot id: A0A143C9H5
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1783515:A4E84 RS26755
gene id: 1783515:A4E84_RS26755
uniprot id: A0A143C6J9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1783515:A4E84 RS16865
gene id: 1783515:A4E84_RS16865
uniprot id: A0A143C0W4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS26245
gene id: 1783515:A4E84_RS26245
uniprot id: A0A143C5G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1783515:A4E84 RS34065
gene id: 1783515:A4E84_RS34065
uniprot id: A0A143C9L9
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

1783515:A4E84 RS26760
gene id: 1783515:A4E84_RS26760
uniprot id: A0A143C6H3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1783515:A4E84 RS29130
gene id: 1783515:A4E84_RS29130
uniprot id: A0A143C6W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1783515:A4E84 RS10035
gene id: 1783515:A4E84_RS10035
uniprot id: A0A143BX68
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24620
gene id: 1783515:A4E84_RS24620
uniprot id: A0A143C4N7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1783515:A4E84 RS42665
gene id: 1783515:A4E84_RS42665
uniprot id: A0A143CBS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1783515:A4E84 RS23705
gene id: 1783515:A4E84_RS23705
uniprot id: A0A143C461
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS14440
gene id: 1783515:A4E84_RS14440
uniprot id: A0A143BZE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1783515:A4E84 RS31430
gene id: 1783515:A4E84_RS31430
uniprot id: A0A143C9H1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS29075
gene id: 1783515:A4E84_RS29075
uniprot id: A0A143C6Z3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS15630
gene id: 1783515:A4E84_RS15630
uniprot id: A0A143C062
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1783515:A4E84 RS32065
gene id: 1783515:A4E84_RS32065
uniprot id: A0A143C919
names: Similarity
messages: Belongs to the catalase family.

1783515:A4E84 RS26585
gene id: 1783515:A4E84_RS26585
uniprot id: A0A143C5P4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1783515:A4E84 RS07175
gene id: 1783515:A4E84_RS07175
uniprot id: A0A143BVQ0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS15375
gene id: 1783515:A4E84_RS15375
uniprot id: A0A143BZV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1783515:A4E84 RS09915
gene id: 1783515:A4E84_RS09915
uniprot id: A0A143BXA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1783515:A4E84 RS02985
gene id: 1783515:A4E84_RS02985
uniprot id: A0A143BTM6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1783515:A4E84 RS21085
gene id: 1783515:A4E84_RS21085
uniprot id: A0A143CDF9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS33320
gene id: 1783515:A4E84_RS33320
uniprot id: A0A143C9R2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS13165
gene id: 1783515:A4E84_RS13165
uniprot id: A0A143BZ50
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1783515:A4E84 RS39135
gene id: 1783515:A4E84_RS39135
uniprot id: A0A143CBY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1783515:A4E84 RS11105
gene id: 1783515:A4E84_RS11105
uniprot id: A0A143BYJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1783515:A4E84 RS28855
gene id: 1783515:A4E84_RS28855
uniprot id: A0A143C6V7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1783515:A4E84 RS34305
gene id: 1783515:A4E84_RS34305
uniprot id: A0A143CAK1
names: Similarity
messages: Belongs to the DapA family.

1783515:A4E84 RS08655
gene id: 1783515:A4E84_RS08655
uniprot id: A0A143BXI8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS04880
gene id: 1783515:A4E84_RS04880
uniprot id: A0A143CCP9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS12605
gene id: 1783515:A4E84_RS12605
uniprot id: A0A143BZA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1783515:A4E84 RS24500
gene id: 1783515:A4E84_RS24500
uniprot id: A0A143C5D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1783515:A4E84 RS16150
gene id: 1783515:A4E84_RS16150
uniprot id: A0A143C0A2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS10560
gene id: 1783515:A4E84_RS10560
uniprot id: A0A143BXR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1783515:A4E84 RS11115
gene id: 1783515:A4E84_RS11115
uniprot id: A0A143BXZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS04380
gene id: 1783515:A4E84_RS04380
uniprot id: A0A143BUH8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1783515:A4E84 RS07980
gene id: 1783515:A4E84_RS07980
uniprot id: A0A143BW18
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1783515:A4E84 RS33415
gene id: 1783515:A4E84_RS33415
uniprot id: A0A143C977
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

1783515:A4E84 RS06095
gene id: 1783515:A4E84_RS06095
uniprot id: A0A143BW93
names: Similarity
messages: Belongs to the peptidase C40 family.

1783515:A4E84 RS08135
gene id: 1783515:A4E84_RS08135
uniprot id: A0A143BW62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1783515:A4E84 RS26330
gene id: 1783515:A4E84_RS26330
uniprot id: A0A143C6B0
names: Similarity
messages: Belongs to the UPF0162 family.

1783515:A4E84 RS06195
gene id: 1783515:A4E84_RS06195
uniprot id: A0A143BV53
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1783515:A4E84 RS17835
gene id: 1783515:A4E84_RS17835
uniprot id: A0A143C203
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS10065
gene id: 1783515:A4E84_RS10065
uniprot id: A0A143BXD9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1783515:A4E84 RS07470
gene id: 1783515:A4E84_RS07470
uniprot id: A0A143BW46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1783515:A4E84 RS19170
gene id: 1783515:A4E84_RS19170
uniprot id: A0A143C1Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1783515:A4E84 RS07730
gene id: 1783515:A4E84_RS07730
uniprot id: A0A143BW61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS13090
gene id: 1783515:A4E84_RS13090
uniprot id: A0A143CE84
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS08785
gene id: 1783515:A4E84_RS08785
uniprot id: A0A143CCX3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS14415
gene id: 1783515:A4E84_RS14415
uniprot id: A0A143BZJ2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS14735
gene id: 1783515:A4E84_RS14735
uniprot id: A0A143BZQ2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS15810
gene id: 1783515:A4E84_RS15810
uniprot id: A0A143C028
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

1783515:A4E84 RS11975
gene id: 1783515:A4E84_RS11975
uniprot id: A0A143BY55
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24110
gene id: 1783515:A4E84_RS24110
uniprot id: A0A143C4K5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1783515:A4E84 RS31490
gene id: 1783515:A4E84_RS31490
uniprot id: A0A143C888
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS09345
gene id: 1783515:A4E84_RS09345
uniprot id: A0A143CCU8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1783515:A4E84 RS08040
gene id: 1783515:A4E84_RS08040
uniprot id: A0A143BW22
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS25920
gene id: 1783515:A4E84_RS25920
uniprot id: A0A143C585
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1783515:A4E84 RS24785
gene id: 1783515:A4E84_RS24785
uniprot id: A0A143C4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS30830
gene id: 1783515:A4E84_RS30830
uniprot id: A0A143C7U9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24605
gene id: 1783515:A4E84_RS24605
uniprot id: A0A143C5H3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1783515:A4E84 RS04100
gene id: 1783515:A4E84_RS04100
uniprot id: A0A143BU21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

1783515:A4E84 RS19780
gene id: 1783515:A4E84_RS19780
uniprot id: A0A143C292
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS21825
gene id: 1783515:A4E84_RS21825
uniprot id: A0A143C340
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS09335
gene id: 1783515:A4E84_RS09335
uniprot id: A0A143BWZ9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

1783515:A4E84 RS16770
gene id: 1783515:A4E84_RS16770
uniprot id: A0A143C0Q9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS10170
gene id: 1783515:A4E84_RS10170
uniprot id: A0A143BXI5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS27695
gene id: 1783515:A4E84_RS27695
uniprot id: A0A143C688
names: Subcellular Location Annotation
messages: Cytoplasm

1783515:A4E84 RS33755
gene id: 1783515:A4E84_RS33755
uniprot id: A0A143CAQ7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1783515:A4E84 RS03970
gene id: 1783515:A4E84_RS03970
uniprot id: A0A143BV69
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1783515:A4E84 RS36770
gene id: 1783515:A4E84_RS36770
uniprot id: A0A143CBU3
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1783515:A4E84 RS33740
gene id: 1783515:A4E84_RS33740
uniprot id: A0A143C9E0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS08670
gene id: 1783515:A4E84_RS08670
uniprot id: A0A143BWQ5
names: Similarity
messages: Belongs to the peptidase S8 family.

1783515:A4E84 RS33085
gene id: 1783515:A4E84_RS33085
uniprot id: A0A143C9Z5
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1783515:A4E84 RS11925
gene id: 1783515:A4E84_RS11925
uniprot id: A0A143BZ85
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1783515:A4E84 RS35765
gene id: 1783515:A4E84_RS35765
uniprot id: A0A143CAB0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1783515:A4E84 RS13715
gene id: 1783515:A4E84_RS13715
uniprot id: A0A143CD40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1783515:A4E84 RS07325
gene id: 1783515:A4E84_RS07325
uniprot id: A0A143BVZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1783515:A4E84 RS02545
gene id: 1783515:A4E84_RS02545
uniprot id: A0A143BTB4
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1783515:A4E84 RS35865
gene id: 1783515:A4E84_RS35865
uniprot id: A0A143CAD5
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

1783515:A4E84 RS04155
gene id: 1783515:A4E84_RS04155
uniprot id: A0A143BVB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

1783515:A4E84 RS20905
gene id: 1783515:A4E84_RS20905
uniprot id: A0A143C3I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1783515:A4E84 RS30090
gene id: 1783515:A4E84_RS30090
uniprot id: A0A143C7F5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1783515:A4E84 RS29435
gene id: 1783515:A4E84_RS29435
uniprot id: A0A143C724
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1783515:A4E84 RS31660
gene id: 1783515:A4E84_RS31660
uniprot id: A0A143C8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS24165
gene id: 1783515:A4E84_RS24165
uniprot id: A0A143C4L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1783515:A4E84 RS18170
gene id: 1783515:A4E84_RS18170
uniprot id: A0A143C255
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS09120
gene id: 1783515:A4E84_RS09120
uniprot id: A0A143BWW7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1783515:A4E84 RS10745
gene id: 1783515:A4E84_RS10745
uniprot id: A0A143BYS6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1783515:A4E84 RS25780
gene id: 1783515:A4E84_RS25780
uniprot id: A0A143C570
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1783515:A4E84 RS16145
gene id: 1783515:A4E84_RS16145
uniprot id: A0A143C1J5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1783515:A4E84 RS10540
gene id: 1783515:A4E84_RS10540
uniprot id: A0A143BXH6
names: Similarity
messages: Belongs to the TrpC family.

1783515:A4E84 RS20000
gene id: 1783515:A4E84_RS20000
uniprot id: A0A143C2C1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS38030
gene id: 1783515:A4E84_RS38030
uniprot id: A0A143CBE9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS37835
gene id: 1783515:A4E84_RS37835
uniprot id: A0A143CBB7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS09165
gene id: 1783515:A4E84_RS09165
uniprot id: A0A143BXL5
names: Similarity
messages: Belongs to the peptidase U62 family.

1783515:A4E84 RS22880
gene id: 1783515:A4E84_RS22880
uniprot id: A0A143C404
names: Similarity
messages: Belongs to the Nth/MutY family.

1783515:A4E84 RS07440
gene id: 1783515:A4E84_RS07440
uniprot id: A0A143BX00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1783515:A4E84 RS04110
gene id: 1783515:A4E84_RS04110
uniprot id: A0A143BV88
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

1783515:A4E84 RS16570
gene id: 1783515:A4E84_RS16570
uniprot id: A0A143C0U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1783515:A4E84 RS30640
gene id: 1783515:A4E84_RS30640
uniprot id: A0A143C7S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS29985
gene id: 1783515:A4E84_RS29985
uniprot id: A0A143C7C6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS01055
gene id: 1783515:A4E84_RS01055
uniprot id: A0A143BSM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS11535
gene id: 1783515:A4E84_RS11535
uniprot id: A0A143BY71
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1783515:A4E84 RS10080
gene id: 1783515:A4E84_RS10080
uniprot id: A0A143BX82
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1783515:A4E84 RS04910
gene id: 1783515:A4E84_RS04910
uniprot id: A0A143BVM9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS33355
gene id: 1783515:A4E84_RS33355
uniprot id: A0A143C947
names: Similarity
messages: Belongs to the peptidase S66 family.

1783515:A4E84 RS36595
gene id: 1783515:A4E84_RS36595
uniprot id: A0A143CAN8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1783515:A4E84 RS03640
gene id: 1783515:A4E84_RS03640
uniprot id: A0A143BU75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS10040
gene id: 1783515:A4E84_RS10040
uniprot id: A0A143BX48
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS04720
gene id: 1783515:A4E84_RS04720
uniprot id: A0A143CCN1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1783515:A4E84 RS26950
gene id: 1783515:A4E84_RS26950
uniprot id: A0A143C5S9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1783515:A4E84 RS39620
gene id: 1783515:A4E84_RS39620
uniprot id: A0A143CDI1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1783515:A4E84 RS22905
gene id: 1783515:A4E84_RS22905
uniprot id: A0A143C554
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

1783515:A4E84 RS30560
gene id: 1783515:A4E84_RS30560
uniprot id: A0A143C7R0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1783515:A4E84 RS03230
gene id: 1783515:A4E84_RS03230
uniprot id: A0A143BU07
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS24370
gene id: 1783515:A4E84_RS24370
uniprot id: A0A143C4J0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1783515:A4E84 RS08890
gene id: 1783515:A4E84_RS08890
uniprot id: A0A143BWR8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1783515:A4E84 RS04540
gene id: 1783515:A4E84_RS04540
uniprot id: A0A143BU93
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

1783515:A4E84 RS07200
gene id: 1783515:A4E84_RS07200
uniprot id: A0A143BVM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1783515:A4E84 RS29315
gene id: 1783515:A4E84_RS29315
uniprot id: A0A143C6Z8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1783515:A4E84 RS09565
gene id: 1783515:A4E84_RS09565
uniprot id: A0A143BWX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1783515:A4E84 RS38085
gene id: 1783515:A4E84_RS38085
uniprot id: A0A143CBF9
names: Similarity
messages: Belongs to the peptidase S1 family.

1783515:A4E84 RS27800
gene id: 1783515:A4E84_RS27800
uniprot id: A0A143C6E5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS14785
gene id: 1783515:A4E84_RS14785
uniprot id: A0A143BZR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS20840
gene id: 1783515:A4E84_RS20840
uniprot id: A0A143C2L6
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1783515:A4E84 RS34395
gene id: 1783515:A4E84_RS34395
uniprot id: A0A143C9M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

1783515:A4E84 RS13315
gene id: 1783515:A4E84_RS13315
uniprot id: A0A143BYW9
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

1783515:A4E84 RS32830
gene id: 1783515:A4E84_RS32830
uniprot id: A0A143C8W6
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1783515:A4E84 RS35700
gene id: 1783515:A4E84_RS35700
uniprot id: A0A143CA96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
messages: In the N-terminal section; belongs to the LPG synthetase family.
messages: Membrane

1783515:A4E84 RS11610
gene id: 1783515:A4E84_RS11610
uniprot id: A0A143BY95
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS34710
gene id: 1783515:A4E84_RS34710
uniprot id: A0A143C9U3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1783515:A4E84 RS31775
gene id: 1783515:A4E84_RS31775
uniprot id: A0A143C8Y0
names: Similarity
messages: Belongs to the CdaR family.

1783515:A4E84 RS30570
gene id: 1783515:A4E84_RS30570
uniprot id: A0A143C920
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1783515:A4E84 RS29225
gene id: 1783515:A4E84_RS29225
uniprot id: A0A143C704
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS28510
gene id: 1783515:A4E84_RS28510
uniprot id: A0A143C6Q8
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1783515:A4E84 RS13255
gene id: 1783515:A4E84_RS13255
uniprot id: A0A143BYV7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1783515:A4E84 RS18795
gene id: 1783515:A4E84_RS18795
uniprot id: A0A143C1S7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1783515:A4E84 RS14185
gene id: 1783515:A4E84_RS14185
uniprot id: A0A143BZG7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1783515:A4E84 RS36200
gene id: 1783515:A4E84_RS36200
uniprot id: A0A143CAI5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS29325
gene id: 1783515:A4E84_RS29325
uniprot id: A0A143C762
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1783515:A4E84 RS27505
gene id: 1783515:A4E84_RS27505
uniprot id: A0A143C659
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1783515:A4E84 RS21405
gene id: 1783515:A4E84_RS21405
uniprot id: A0A143C3S9
names: Subcellular Location Annotation
messages: Cytoplasm

1783515:A4E84 RS29405
gene id: 1783515:A4E84_RS29405
uniprot id: A0A143C7T1
names: Similarity
messages: Belongs to the Dps family.

1783515:A4E84 RS17245
gene id: 1783515:A4E84_RS17245
uniprot id: A0A143C0S0
names: Similarity
messages: Belongs to the peptidase S11 family.

1783515:A4E84 RS10530
gene id: 1783515:A4E84_RS10530
uniprot id: A0A143BYN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1783515:A4E84 RS28975
gene id: 1783515:A4E84_RS28975
uniprot id: A0A143C6Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS10585
gene id: 1783515:A4E84_RS10585
uniprot id: A0A143BYP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

1783515:A4E84 RS28915
gene id: 1783515:A4E84_RS28915
uniprot id: A0A143C6U6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS14030
gene id: 1783515:A4E84_RS14030
uniprot id: A0A143C006
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS09545
gene id: 1783515:A4E84_RS09545
uniprot id: A0A143BX34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1783515:A4E84 RS05310
gene id: 1783515:A4E84_RS05310
uniprot id: A0A143BV21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS30085
gene id: 1783515:A4E84_RS30085
uniprot id: A0A143C7E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS05505
gene id: 1783515:A4E84_RS05505
uniprot id: A0A143BUT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1783515:A4E84 RS20855
gene id: 1783515:A4E84_RS20855
uniprot id: A0A143C3I0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS03910
gene id: 1783515:A4E84_RS03910
uniprot id: A0A143BTZ4
names: Similarity
messages: Belongs to the peptidase A31 family.

1783515:A4E84 RS25285
gene id: 1783515:A4E84_RS25285
uniprot id: A0A143C4Z2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS12505
gene id: 1783515:A4E84_RS12505
uniprot id: A0A143BYS2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1783515:A4E84 RS32670
gene id: 1783515:A4E84_RS32670
uniprot id: A0A143C9C2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS05345
gene id: 1783515:A4E84_RS05345
uniprot id: A0A143BVW1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS32075
gene id: 1783515:A4E84_RS32075
uniprot id: A0A143C8I7
names: Similarity
messages: Belongs to the hyi family.

1783515:A4E84 RS08270
gene id: 1783515:A4E84_RS08270
uniprot id: A0A143BWI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1783515:A4E84 RS16340
gene id: 1783515:A4E84_RS16340
uniprot id: A0A143C1J1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS29185
gene id: 1783515:A4E84_RS29185
uniprot id: A0A143C8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS25280
gene id: 1783515:A4E84_RS25280
uniprot id: A0A143C4X8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS06165
gene id: 1783515:A4E84_RS06165
uniprot id: A0A143BVG3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS07455
gene id: 1783515:A4E84_RS07455
uniprot id: A0A143BVS4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1783515:A4E84 RS12900
gene id: 1783515:A4E84_RS12900
uniprot id: A0A143BYU2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1783515:A4E84 RS35840
gene id: 1783515:A4E84_RS35840
uniprot id: A0A143CAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1783515:A4E84 RS13720
gene id: 1783515:A4E84_RS13720
uniprot id: A0A143BZ34
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1783515:A4E84 RS02465
gene id: 1783515:A4E84_RS02465
uniprot id: A0A143BTN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1783515:A4E84 RS24195
gene id: 1783515:A4E84_RS24195
uniprot id: A0A143C4A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1783515:A4E84 RS16550
gene id: 1783515:A4E84_RS16550
uniprot id: A0A143C0H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1783515:A4E84 RS27765
gene id: 1783515:A4E84_RS27765
uniprot id: A0A143C7M1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1783515:A4E84 RS34630
gene id: 1783515:A4E84_RS34630
uniprot id: A0A143C9R4
names: Similarity
messages: Belongs to the peptidase M1 family.

1783515:A4E84 RS30550
gene id: 1783515:A4E84_RS30550
uniprot id: A0A143C7R1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS08640
gene id: 1783515:A4E84_RS08640
uniprot id: A0A143BWE0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS12780
gene id: 1783515:A4E84_RS12780
uniprot id: A0A143BYS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS25410
gene id: 1783515:A4E84_RS25410
uniprot id: A0A143C5W5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1783515:A4E84 RS27475
gene id: 1783515:A4E84_RS27475
uniprot id: A0A143C695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS03050
gene id: 1783515:A4E84_RS03050
uniprot id: A0A143BTK4
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1783515:A4E84 RS12570
gene id: 1783515:A4E84_RS12570
uniprot id: A0A143BYR2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS28545
gene id: 1783515:A4E84_RS28545
uniprot id: A0A143C826
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1783515:A4E84 RS31310
gene id: 1783515:A4E84_RS31310
uniprot id: A0A143C861
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS36920
gene id: 1783515:A4E84_RS36920
uniprot id: A0A143CAV3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS13545
gene id: 1783515:A4E84_RS13545
uniprot id: A0A143BZ06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1783515:A4E84 RS23775
gene id: 1783515:A4E84_RS23775
uniprot id: A0A143C436
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1783515:A4E84 RS07635
gene id: 1783515:A4E84_RS07635
uniprot id: A0A143BWV5
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1783515:A4E84 RS37750
gene id: 1783515:A4E84_RS37750
uniprot id: A0A143CCK8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1783515:A4E84 RS29055
gene id: 1783515:A4E84_RS29055
uniprot id: A0A143C7M0
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

1783515:A4E84 RS09155
gene id: 1783515:A4E84_RS09155
uniprot id: A0A143BWM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1783515:A4E84 RS19800
gene id: 1783515:A4E84_RS19800
uniprot id: A0A143C288
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1783515:A4E84 RS35535
gene id: 1783515:A4E84_RS35535
uniprot id: A0A143CA66
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1783515:A4E84 RS33715
gene id: 1783515:A4E84_RS33715
uniprot id: A0A143C9C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1783515:A4E84 RS13655
gene id: 1783515:A4E84_RS13655
uniprot id: A0A143CD16
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS13905
gene id: 1783515:A4E84_RS13905
uniprot id: A0A143C079
names: Similarity
messages: Belongs to the peptidase M1 family.

1783515:A4E84 RS11245
gene id: 1783515:A4E84_RS11245
uniprot id: A0A143BXR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1783515:A4E84 RS09580
gene id: 1783515:A4E84_RS09580
uniprot id: A0A143BXZ7
names: Similarity
messages: Belongs to the IlvD/Edd family.

1783515:A4E84 RS16740
gene id: 1783515:A4E84_RS16740
uniprot id: A0A143C0S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1783515:A4E84 RS19785
gene id: 1783515:A4E84_RS19785
uniprot id: A0A143C3E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1783515:A4E84 RS14035
gene id: 1783515:A4E84_RS14035
uniprot id: A0A143BZL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS01520
gene id: 1783515:A4E84_RS01520
uniprot id: A0A143CDE6
names: Similarity
messages: Belongs to the peptidase M1 family.

1783515:A4E84 RS01910
gene id: 1783515:A4E84_RS01910
uniprot id: A0A143BTD0
names: Similarity
messages: Belongs to the catalase family.

1783515:A4E84 RS20615
gene id: 1783515:A4E84_RS20615
uniprot id: A0A143C2N8
names: Similarity
messages: Belongs to the cytochrome P450 family.

1783515:A4E84 RS06855
gene id: 1783515:A4E84_RS06855
uniprot id: A0A143BWM7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1783515:A4E84 RS17940
gene id: 1783515:A4E84_RS17940
uniprot id: A0A143C148
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1783515:A4E84 RS35875
gene id: 1783515:A4E84_RS35875
uniprot id: A0A143CAE7
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

1783515:A4E84 RS28585
gene id: 1783515:A4E84_RS28585
uniprot id: A0A143C6Q1
names: Similarity
messages: Belongs to the acylphosphatase family.

1783515:A4E84 RS03470
gene id: 1783515:A4E84_RS03470
uniprot id: A0A143BUS3
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1783515:A4E84 RS10330
gene id: 1783515:A4E84_RS10330
uniprot id: A0A143BYE5
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1783515:A4E84 RS29320
gene id: 1783515:A4E84_RS29320
uniprot id: A0A143C710
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1783515:A4E84 RS36050
gene id: 1783515:A4E84_RS36050
uniprot id: A0A143CAH4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1783515:A4E84 RS17240
gene id: 1783515:A4E84_RS17240
uniprot id: A0A143C240
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS21435
gene id: 1783515:A4E84_RS21435
uniprot id: A0A143C4A8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS28290
gene id: 1783515:A4E84_RS28290
uniprot id: A0A143C7C0
names: Similarity
messages: Belongs to the agmatine deiminase family.

1783515:A4E84 RS10695
gene id: 1783515:A4E84_RS10695
uniprot id: A0A143BXJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1783515:A4E84 RS08870
gene id: 1783515:A4E84_RS08870
uniprot id: A0A143BXM6
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1783515:A4E84 RS37370
gene id: 1783515:A4E84_RS37370
uniprot id: A0A143CB28
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS09845
gene id: 1783515:A4E84_RS09845
uniprot id: A0A143BY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS10710
gene id: 1783515:A4E84_RS10710
uniprot id: A0A143BYM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1783515:A4E84 RS02055
gene id: 1783515:A4E84_RS02055
uniprot id: A0A143BUA7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1783515:A4E84 RS25310
gene id: 1783515:A4E84_RS25310
uniprot id: A0A143C5U6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS26190
gene id: 1783515:A4E84_RS26190
uniprot id: A0A143C5F3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1783515:A4E84 RS11950
gene id: 1783515:A4E84_RS11950
uniprot id: A0A143BYD5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS34840
gene id: 1783515:A4E84_RS34840
uniprot id: A0A143C9V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm

1783515:A4E84 RS33095
gene id: 1783515:A4E84_RS33095
uniprot id: A0A143C923
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1783515:A4E84 RS07695
gene id: 1783515:A4E84_RS07695
uniprot id: A0A143BVY8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1783515:A4E84 RS13085
gene id: 1783515:A4E84_RS13085
uniprot id: A0A143BYR9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1783515:A4E84 RS36145
gene id: 1783515:A4E84_RS36145
uniprot id: A0A143CBK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1783515:A4E84 RS25925
gene id: 1783515:A4E84_RS25925
uniprot id: A0A143C5C0
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1783515:A4E84 RS23735
gene id: 1783515:A4E84_RS23735
uniprot id: A0A143C536
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS26445
gene id: 1783515:A4E84_RS26445
uniprot id: A0A143C5P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1783515:A4E84 RS02430
gene id: 1783515:A4E84_RS02430
uniprot id: A0A143BT95
names: Similarity
messages: Belongs to the melC1 family.

1783515:A4E84 RS37150
gene id: 1783515:A4E84_RS37150
uniprot id: A0A143CAX9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS14625
gene id: 1783515:A4E84_RS14625
uniprot id: A0A143BZW2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS19375
gene id: 1783515:A4E84_RS19375
uniprot id: A0A143C1V2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1783515:A4E84 RS32805
gene id: 1783515:A4E84_RS32805
uniprot id: A0A143CA44
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS09945
gene id: 1783515:A4E84_RS09945
uniprot id: A0A143BY64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1783515:A4E84 RS03305
gene id: 1783515:A4E84_RS03305
uniprot id: A0A143CCK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

1783515:A4E84 RS22655
gene id: 1783515:A4E84_RS22655
uniprot id: A0A143C4J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1783515:A4E84 RS24000
gene id: 1783515:A4E84_RS24000
uniprot id: A0A143C456
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS10735
gene id: 1783515:A4E84_RS10735
uniprot id: A0A143BXQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1783515:A4E84 RS16760
gene id: 1783515:A4E84_RS16760
uniprot id: A0A143C0J2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1783515:A4E84 RS06445
gene id: 1783515:A4E84_RS06445
uniprot id: A0A143BVJ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1783515:A4E84 RS02845
gene id: 1783515:A4E84_RS02845
uniprot id: A0A143BTU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS07070
gene id: 1783515:A4E84_RS07070
uniprot id: A0A143BVJ8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS09050
gene id: 1783515:A4E84_RS09050
uniprot id: A0A143BXP9
names: Similarity
messages: Belongs to the UPF0098 family.

1783515:A4E84 RS05190
gene id: 1783515:A4E84_RS05190
uniprot id: A0A143BUY7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1783515:A4E84 RS06935
gene id: 1783515:A4E84_RS06935
uniprot id: A0A143BVU5
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1783515:A4E84 RS12915
gene id: 1783515:A4E84_RS12915
uniprot id: A0A143BZV9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1783515:A4E84 RS05965
gene id: 1783515:A4E84_RS05965
uniprot id: A0A143BW98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS11305
gene id: 1783515:A4E84_RS11305
uniprot id: A0A143BYN0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS27225
gene id: 1783515:A4E84_RS27225
uniprot id: A0A143C5U1
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1783515:A4E84 RS32490
gene id: 1783515:A4E84_RS32490
uniprot id: A0A143C8Q4
names: Subcellular Location Annotation
messages: Cytoplasm

1783515:A4E84 RS13595
gene id: 1783515:A4E84_RS13595
uniprot id: A0A143BZ15
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1783515:A4E84 RS14780
gene id: 1783515:A4E84_RS14780
uniprot id: A0A143BZZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS21520
gene id: 1783515:A4E84_RS21520
uniprot id: A0A143C3A4
names: Similarity
messages: Belongs to the CdaR family.

1783515:A4E84 RS20035
gene id: 1783515:A4E84_RS20035
uniprot id: A0A143C336
names: Similarity
messages: Belongs to the ParB family.

1783515:A4E84 RS19870
gene id: 1783515:A4E84_RS19870
uniprot id: A0A143C306
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS02255
gene id: 1783515:A4E84_RS02255
uniprot id: A0A143BT63
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS14390
gene id: 1783515:A4E84_RS14390
uniprot id: A0A143BZD6
names: Similarity
messages: Belongs to the TPP enzyme family.

1783515:A4E84 RS37245
gene id: 1783515:A4E84_RS37245
uniprot id: A0A143CB18
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1783515:A4E84 RS31655
gene id: 1783515:A4E84_RS31655
uniprot id: A0A143C8C5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1783515:A4E84 RS22555
gene id: 1783515:A4E84_RS22555
uniprot id: A0A143C3U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1783515:A4E84 RS11515
gene id: 1783515:A4E84_RS11515
uniprot id: A0A143BZ20
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1783515:A4E84 RS17265
gene id: 1783515:A4E84_RS17265
uniprot id: A0A143C1Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1783515:A4E84 RS13575
gene id: 1783515:A4E84_RS13575
uniprot id: A0A143BZ69
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1783515:A4E84 RS38985
gene id: 1783515:A4E84_RS38985
uniprot id: A0A143CBX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1783515:A4E84 RS08965
gene id: 1783515:A4E84_RS08965
uniprot id: A0A143CCV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS15205
gene id: 1783515:A4E84_RS15205
uniprot id: A0A143C110
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS27525
gene id: 1783515:A4E84_RS27525
uniprot id: A0A143C6A0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS02700
gene id: 1783515:A4E84_RS02700
uniprot id: A0A143BUM0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1783515:A4E84 RS07405
gene id: 1783515:A4E84_RS07405
uniprot id: A0A143BVR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS32110
gene id: 1783515:A4E84_RS32110
uniprot id: A0A143C8K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1783515:A4E84 RS35005
gene id: 1783515:A4E84_RS35005
uniprot id: A0A143CB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS08435
gene id: 1783515:A4E84_RS08435
uniprot id: A0A143BWL5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS05665
gene id: 1783515:A4E84_RS05665
uniprot id: A0A143BW47
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1783515:A4E84 RS34365
gene id: 1783515:A4E84_RS34365
uniprot id: A0A143C9M9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS09890
gene id: 1783515:A4E84_RS09890
uniprot id: A0A143BX16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1783515:A4E84 RS15970
gene id: 1783515:A4E84_RS15970
uniprot id: A0A143C0F1
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1783515:A4E84 RS39815
gene id: 1783515:A4E84_RS39815
uniprot id: A0A143CE79
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS39205
gene id: 1783515:A4E84_RS39205
uniprot id: A0A143CDB1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS30670
gene id: 1783515:A4E84_RS30670
uniprot id: A0A143C7R2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS09795
gene id: 1783515:A4E84_RS09795
uniprot id: A0A143BXX5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS10335
gene id: 1783515:A4E84_RS10335
uniprot id: A0A143BY74
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1783515:A4E84 RS36210
gene id: 1783515:A4E84_RS36210
uniprot id: A0A143CB47
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1783515:A4E84 RS34875
gene id: 1783515:A4E84_RS34875
uniprot id: A0A143CA16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1783515:A4E84 RS34885
gene id: 1783515:A4E84_RS34885
uniprot id: A0A143CAY7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS33250
gene id: 1783515:A4E84_RS33250
uniprot id: A0A143C942
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS09645
gene id: 1783515:A4E84_RS09645
uniprot id: A0A143BXA1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS33235
gene id: 1783515:A4E84_RS33235
uniprot id: A0A143CF55
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1783515:A4E84 RS19790
gene id: 1783515:A4E84_RS19790
uniprot id: A0A143C1Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1783515:A4E84 RS38770
gene id: 1783515:A4E84_RS38770
uniprot id: A0A143CBS9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS19705
gene id: 1783515:A4E84_RS19705
uniprot id: A0A143C2C6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1783515:A4E84 RS16135
gene id: 1783515:A4E84_RS16135
uniprot id: A0A143C0J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1783515:A4E84 RS08765
gene id: 1783515:A4E84_RS08765
uniprot id: A0A143BXF4
names: Similarity
messages: Belongs to the peptidase S1 family.

1783515:A4E84 RS19665
gene id: 1783515:A4E84_RS19665
uniprot id: A0A143C265
names: Similarity
messages: Belongs to the peptidase M24B family.

1783515:A4E84 RS11290
gene id: 1783515:A4E84_RS11290
uniprot id: A0A143BXV1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1783515:A4E84 RS24700
gene id: 1783515:A4E84_RS24700
uniprot id: A0A143C4P7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1783515:A4E84 RS03765
gene id: 1783515:A4E84_RS03765
uniprot id: A0A143BUA0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS15505
gene id: 1783515:A4E84_RS15505
uniprot id: A0A143C0R2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1783515:A4E84 RS29030
gene id: 1783515:A4E84_RS29030
uniprot id: A0A143C6T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS24950
gene id: 1783515:A4E84_RS24950
uniprot id: A0A143CDG7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS13055
gene id: 1783515:A4E84_RS13055
uniprot id: A0A143BZ31
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1783515:A4E84 RS32820
gene id: 1783515:A4E84_RS32820
uniprot id: A0A143C8V5
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1783515:A4E84 RS20860
gene id: 1783515:A4E84_RS20860
uniprot id: A0A143C2Z9
names: Similarity
messages: Belongs to the pirin family.

1783515:A4E84 RS36115
gene id: 1783515:A4E84_RS36115
uniprot id: A0A143CAH8
names: Similarity
messages: Belongs to the CapA family.

1783515:A4E84 RS28935
gene id: 1783515:A4E84_RS28935
uniprot id: A0A143C881
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1783515:A4E84 RS03105
gene id: 1783515:A4E84_RS03105
uniprot id: A0A143BUT4
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS07230
gene id: 1783515:A4E84_RS07230
uniprot id: A0A143BVX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1783515:A4E84 RS08935
gene id: 1783515:A4E84_RS08935
uniprot id: A0A143BWW3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS29645
gene id: 1783515:A4E84_RS29645
uniprot id: A0A143C789
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1783515:A4E84 RS36945
gene id: 1783515:A4E84_RS36945
uniprot id: A0A143CAV1
names: Similarity
messages: Belongs to the TPP enzyme family.

1783515:A4E84 RS07890
gene id: 1783515:A4E84_RS07890
uniprot id: A0A143CCT0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1783515:A4E84 RS38310
gene id: 1783515:A4E84_RS38310
uniprot id: A0A143CBJ8
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

1783515:A4E84 RS31905
gene id: 1783515:A4E84_RS31905
uniprot id: A0A143C8F7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1783515:A4E84 RS34030
gene id: 1783515:A4E84_RS34030
uniprot id: A0A143C9H0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1783515:A4E84 RS34450
gene id: 1783515:A4E84_RS34450
uniprot id: A0A143C9N3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1783515:A4E84 RS39270
gene id: 1783515:A4E84_RS39270
uniprot id: A0A143CDC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1783515:A4E84 RS31735
gene id: 1783515:A4E84_RS31735
uniprot id: A0A143C8B0
names: Similarity
messages: Belongs to the TPP enzyme family.

1783515:A4E84 RS25335
gene id: 1783515:A4E84_RS25335
uniprot id: A0A143C502
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24060
gene id: 1783515:A4E84_RS24060
uniprot id: A0A143C4E5
names: Similarity
messages: Belongs to the UPF0336 family.

1783515:A4E84 RS35170
gene id: 1783515:A4E84_RS35170
uniprot id: A0A143CA64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

1783515:A4E84 RS21215
gene id: 1783515:A4E84_RS21215
uniprot id: A0A143C2Z4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24400
gene id: 1783515:A4E84_RS24400
uniprot id: A0A143C4K3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1783515:A4E84 RS33735
gene id: 1783515:A4E84_RS33735
uniprot id: A0A143C9C5
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1783515:A4E84 RS11360
gene id: 1783515:A4E84_RS11360
uniprot id: A0A143BYZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1783515:A4E84 RS03135
gene id: 1783515:A4E84_RS03135
uniprot id: A0A143BTL3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1783515:A4E84 RS23155
gene id: 1783515:A4E84_RS23155
uniprot id: A0A143C3T4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS16830
gene id: 1783515:A4E84_RS16830
uniprot id: A0A143C0S1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24285
gene id: 1783515:A4E84_RS24285
uniprot id: A0A143C4I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1783515:A4E84 RS16325
gene id: 1783515:A4E84_RS16325
uniprot id: A0A143C0C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1783515:A4E84 RS23075
gene id: 1783515:A4E84_RS23075
uniprot id: A0A143C3U6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1783515:A4E84 RS16430
gene id: 1783515:A4E84_RS16430
uniprot id: A0A143C0N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1783515:A4E84 RS10785
gene id: 1783515:A4E84_RS10785
uniprot id: A0A143BXT4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS02555
gene id: 1783515:A4E84_RS02555
uniprot id: A0A143BUD3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS25325
gene id: 1783515:A4E84_RS25325
uniprot id: A0A143C514
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS33045
gene id: 1783515:A4E84_RS33045
uniprot id: A0A143C8Z8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1783515:A4E84 RS25575
gene id: 1783515:A4E84_RS25575
uniprot id: A0A143C4Z3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1783515:A4E84 RS28735
gene id: 1783515:A4E84_RS28735
uniprot id: A0A143C6T6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1783515:A4E84 RS30310
gene id: 1783515:A4E84_RS30310
uniprot id: A0A143C8X9
names: Similarity
messages: Belongs to the thioesterase family.

1783515:A4E84 RS27360
gene id: 1783515:A4E84_RS27360
uniprot id: A0A143C636
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1783515:A4E84 RS30140
gene id: 1783515:A4E84_RS30140
uniprot id: A0A143C7F4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS31920
gene id: 1783515:A4E84_RS31920
uniprot id: A0A143C8E6
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1783515:A4E84 RS09790
gene id: 1783515:A4E84_RS09790
uniprot id: A0A143BY36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS21335
gene id: 1783515:A4E84_RS21335
uniprot id: A0A143C2U3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1783515:A4E84 RS22790
gene id: 1783515:A4E84_RS22790
uniprot id: A0A143CDE2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1783515:A4E84 RS10630
gene id: 1783515:A4E84_RS10630
uniprot id: A0A143BXS3
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1783515:A4E84 RS09065
gene id: 1783515:A4E84_RS09065
uniprot id: A0A143BWW1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS01390
gene id: 1783515:A4E84_RS01390
uniprot id: A0A143BTZ7
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS04050
gene id: 1783515:A4E84_RS04050
uniprot id: A0A143BV78
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS09755
gene id: 1783515:A4E84_RS09755
uniprot id: A0A143BX80
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1783515:A4E84 RS11810
gene id: 1783515:A4E84_RS11810
uniprot id: A0A143BYX0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS06625
gene id: 1783515:A4E84_RS06625
uniprot id: A0A143BVC3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS39715
gene id: 1783515:A4E84_RS39715
uniprot id: A0A143CC88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1783515:A4E84 RS39340
gene id: 1783515:A4E84_RS39340
uniprot id: A0A143CC54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1783515:A4E84 RS07260
gene id: 1783515:A4E84_RS07260
uniprot id: A0A143BWM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1783515:A4E84 RS29420
gene id: 1783515:A4E84_RS29420
uniprot id: A0A143C773
names: Similarity
messages: Belongs to the FPG family.

1783515:A4E84 RS37960
gene id: 1783515:A4E84_RS37960
uniprot id: A0A143CBD6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS07590
gene id: 1783515:A4E84_RS07590
uniprot id: A0A143BW59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS24865
gene id: 1783515:A4E84_RS24865
uniprot id: A0A143C4N1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1783515:A4E84 RS27675
gene id: 1783515:A4E84_RS27675
uniprot id: A0A143C713
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1783515:A4E84 RS04590
gene id: 1783515:A4E84_RS04590
uniprot id: A0A143BUD8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1783515:A4E84 RS33005
gene id: 1783515:A4E84_RS33005
uniprot id: A0A143C8Z3
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1783515:A4E84 RS22345
gene id: 1783515:A4E84_RS22345
uniprot id: A0A143C4V8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1783515:A4E84 RS08195
gene id: 1783515:A4E84_RS08195
uniprot id: A0A143BW65
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1783515:A4E84 RS12555
gene id: 1783515:A4E84_RS12555
uniprot id: A0A143BYS9
names: Similarity
messages: Belongs to the aldose epimerase family.

1783515:A4E84 RS23455
gene id: 1783515:A4E84_RS23455
uniprot id: A0A143C4V0
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1783515:A4E84 RS30685
gene id: 1783515:A4E84_RS30685
uniprot id: A0A143C7U7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS15880
gene id: 1783515:A4E84_RS15880
uniprot id: A0A143C037
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS21345
gene id: 1783515:A4E84_RS21345
uniprot id: A0A143C310
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1783515:A4E84 RS07520
gene id: 1783515:A4E84_RS07520
uniprot id: A0A143BWS2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS36590
gene id: 1783515:A4E84_RS36590
uniprot id: A0A143CBS1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1783515:A4E84 RS27555
gene id: 1783515:A4E84_RS27555
uniprot id: A0A143C670
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1783515:A4E84 RS25820
gene id: 1783515:A4E84_RS25820
uniprot id: A0A143C5E9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS04755
gene id: 1783515:A4E84_RS04755
uniprot id: A0A143BVL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS13150
gene id: 1783515:A4E84_RS13150
uniprot id: A0A143BYT3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS17730
gene id: 1783515:A4E84_RS17730
uniprot id: A0A143C1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS22025
gene id: 1783515:A4E84_RS22025
uniprot id: A0A143C3H3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1783515:A4E84 RS36440
gene id: 1783515:A4E84_RS36440
uniprot id: A0A143CC03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LigB/MhpB extradiol dioxygenase family.
messages: Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
messages: Homotetramer.

1783515:A4E84 RS34105
gene id: 1783515:A4E84_RS34105
uniprot id: A0A143C9G8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1783515:A4E84 RS32935
gene id: 1783515:A4E84_RS32935
uniprot id: A0A143CA81
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS26770
gene id: 1783515:A4E84_RS26770
uniprot id: A0A143C5S1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1783515:A4E84 RS05650
gene id: 1783515:A4E84_RS05650
uniprot id: A0A143BV77
names: Similarity
messages: Belongs to the UPF0047 family.

1783515:A4E84 RS25360
gene id: 1783515:A4E84_RS25360
uniprot id: A0A143C5V1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS17475
gene id: 1783515:A4E84_RS17475
uniprot id: A0A143C284
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

1783515:A4E84 RS14925
gene id: 1783515:A4E84_RS14925
uniprot id: A0A143BZP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS19955
gene id: 1783515:A4E84_RS19955
uniprot id: A0A143C3G7
names: Similarity
messages: Belongs to the FemABX family.

1783515:A4E84 RS24345
gene id: 1783515:A4E84_RS24345
uniprot id: A0A143C4H3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1783515:A4E84 RS24190
gene id: 1783515:A4E84_RS24190
uniprot id: A0A143C489
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1783515:A4E84 RS32100
gene id: 1783515:A4E84_RS32100
uniprot id: A0A143C8I1
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

1783515:A4E84 RS19670
gene id: 1783515:A4E84_RS19670
uniprot id: A0A143C271
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1783515:A4E84 RS23840
gene id: 1783515:A4E84_RS23840
uniprot id: A0A143C447
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1783515:A4E84 RS11330
gene id: 1783515:A4E84_RS11330
uniprot id: A0A143BY12
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS34920
gene id: 1783515:A4E84_RS34920
uniprot id: A0A143C9X7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS05690
gene id: 1783515:A4E84_RS05690
uniprot id: A0A143BW24
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS22580
gene id: 1783515:A4E84_RS22580
uniprot id: A0A143C3F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1783515:A4E84 RS06065
gene id: 1783515:A4E84_RS06065
uniprot id: A0A143CCP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1783515:A4E84 RS19735
gene id: 1783515:A4E84_RS19735
uniprot id: A0A143C3C5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS08895
gene id: 1783515:A4E84_RS08895
uniprot id: A0A143BWT9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1783515:A4E84 RS30840
gene id: 1783515:A4E84_RS30840
uniprot id: A0A143C7V1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS18040
gene id: 1783515:A4E84_RS18040
uniprot id: A0A143C176
names: Subcellular Location Annotation
messages: Cytoplasm

1783515:A4E84 RS09325
gene id: 1783515:A4E84_RS09325
uniprot id: A0A143BX42
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS28080
gene id: 1783515:A4E84_RS28080
uniprot id: A0A143C6J2
names: Similarity
messages: Belongs to the LOG family.

1783515:A4E84 RS31240
gene id: 1783515:A4E84_RS31240
uniprot id: A0A143C832
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1783515:A4E84 RS29270
gene id: 1783515:A4E84_RS29270
uniprot id: A0A143CDM7
names: Similarity
messages: Belongs to the EccD/Snm4 family.

1783515:A4E84 RS13925
gene id: 1783515:A4E84_RS13925
uniprot id: A0A143BZD2
names: Similarity
messages: Belongs to the peptidase S8 family.

1783515:A4E84 RS06880
gene id: 1783515:A4E84_RS06880
uniprot id: A0A143BVR4
names: Similarity
messages: Belongs to the oxoprolinase family.

1783515:A4E84 RS17670
gene id: 1783515:A4E84_RS17670
uniprot id: A0A143C1W9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1783515:A4E84 RS27390
gene id: 1783515:A4E84_RS27390
uniprot id: A0A143C608
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS15945
gene id: 1783515:A4E84_RS15945
uniprot id: A0A143C098
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1783515:A4E84 RS08075
gene id: 1783515:A4E84_RS08075
uniprot id: A0A143BXB2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS29625
gene id: 1783515:A4E84_RS29625
uniprot id: A0A143C7W1
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1783515:A4E84 RS12565
gene id: 1783515:A4E84_RS12565
uniprot id: A0A143BYN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS35570
gene id: 1783515:A4E84_RS35570
uniprot id: A0A143CAD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1783515:A4E84 RS01415
gene id: 1783515:A4E84_RS01415
uniprot id: A0A143BTU8
names: Similarity
messages: Belongs to the ComB family.

1783515:A4E84 RS12045
gene id: 1783515:A4E84_RS12045
uniprot id: A0A143BZ13
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1783515:A4E84 RS26115
gene id: 1783515:A4E84_RS26115
uniprot id: A0A143C641
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1783515:A4E84 RS37005
gene id: 1783515:A4E84_RS37005
uniprot id: A0A143CEJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1783515:A4E84 RS21695
gene id: 1783515:A4E84_RS21695
uniprot id: A0A143C3D4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS29285
gene id: 1783515:A4E84_RS29285
uniprot id: A0A143C7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1783515:A4E84 RS31990
gene id: 1783515:A4E84_RS31990
uniprot id: A0A143C8H5
names: Similarity
messages: Belongs to the peptidase S1B family.

1783515:A4E84 RS07280
gene id: 1783515:A4E84_RS07280
uniprot id: A0A143BVZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS24820
gene id: 1783515:A4E84_RS24820
uniprot id: A0A143C4N2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1783515:A4E84 RS29220
gene id: 1783515:A4E84_RS29220
uniprot id: A0A143C745
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

1783515:A4E84 RS03675
gene id: 1783515:A4E84_RS03675
uniprot id: A0A143BTV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1783515:A4E84 RS39130
gene id: 1783515:A4E84_RS39130
uniprot id: A0A143CBY9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1783515:A4E84 RS36120
gene id: 1783515:A4E84_RS36120
uniprot id: A0A143CDX9
names: Similarity
messages: Belongs to the archease family.

1783515:A4E84 RS27425
gene id: 1783515:A4E84_RS27425
uniprot id: A0A143C680
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1783515:A4E84 RS16100
gene id: 1783515:A4E84_RS16100
uniprot id: A0A143C0B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1783515:A4E84 RS02850
gene id: 1783515:A4E84_RS02850
uniprot id: A0A143BTT9
names: Similarity
messages: Belongs to the CsoR family.

1783515:A4E84 RS31895
gene id: 1783515:A4E84_RS31895
uniprot id: A0A143C8Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1783515:A4E84 RS07560
gene id: 1783515:A4E84_RS07560
uniprot id: A0A143BVV2
names: Similarity
messages: Belongs to the CdaR family.

1783515:A4E84 RS29190
gene id: 1783515:A4E84_RS29190
uniprot id: A0A143C6X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS27535
gene id: 1783515:A4E84_RS27535
uniprot id: A0A143C666
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS29090
gene id: 1783515:A4E84_RS29090
uniprot id: A0A143C6U9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1783515:A4E84 RS09190
gene id: 1783515:A4E84_RS09190
uniprot id: A0A143BXV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1783515:A4E84 RS37700
gene id: 1783515:A4E84_RS37700
uniprot id: A0A143CB89
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1783515:A4E84 RS03725
gene id: 1783515:A4E84_RS03725
uniprot id: A0A143BTZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS37890
gene id: 1783515:A4E84_RS37890
uniprot id: A0A143CBU9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS02915
gene id: 1783515:A4E84_RS02915
uniprot id: A0A143BTW1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1783515:A4E84 RS24140
gene id: 1783515:A4E84_RS24140
uniprot id: A0A143C477
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1783515:A4E84 RS10760
gene id: 1783515:A4E84_RS10760
uniprot id: A0A143BXJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS23720
gene id: 1783515:A4E84_RS23720
uniprot id: A0A143C408
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS32475
gene id: 1783515:A4E84_RS32475
uniprot id: A0A143C8Q2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1783515:A4E84 RS22940
gene id: 1783515:A4E84_RS22940
uniprot id: A0A143C3X1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS06060
gene id: 1783515:A4E84_RS06060
uniprot id: A0A143BVC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1783515:A4E84 RS01030
gene id: 1783515:A4E84_RS01030
uniprot id: A0A143BSZ1
names: Similarity
messages: Belongs to the AHA1 family.

1783515:A4E84 RS30810
gene id: 1783515:A4E84_RS30810
uniprot id: A0A143C8R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS24580
gene id: 1783515:A4E84_RS24580
uniprot id: A0A143C4N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1783515:A4E84 RS01905
gene id: 1783515:A4E84_RS01905
uniprot id: A0A143BTC9
names: Similarity
messages: Belongs to the fructosamine kinase family.

1783515:A4E84 RS02470
gene id: 1783515:A4E84_RS02470
uniprot id: A0A143BUI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS11375
gene id: 1783515:A4E84_RS11375
uniprot id: A0A143BY43
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS16010
gene id: 1783515:A4E84_RS16010
uniprot id: A0A143C1A7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1783515:A4E84 RS13815
gene id: 1783515:A4E84_RS13815
uniprot id: A0A143BZB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1783515:A4E84 RS22690
gene id: 1783515:A4E84_RS22690
uniprot id: A0A143C3H9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1783515:A4E84 RS05055
gene id: 1783515:A4E84_RS05055
uniprot id: A0A143BUN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1783515:A4E84 RS15405
gene id: 1783515:A4E84_RS15405
uniprot id: A0A143C026
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS13000
gene id: 1783515:A4E84_RS13000
uniprot id: A0A143BZ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS06230
gene id: 1783515:A4E84_RS06230
uniprot id: A0A143BVF0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1783515:A4E84 RS09780
gene id: 1783515:A4E84_RS09780
uniprot id: A0A143BX15
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1783515:A4E84 RS27470
gene id: 1783515:A4E84_RS27470
uniprot id: A0A143C6X0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1783515:A4E84 RS04750
gene id: 1783515:A4E84_RS04750
uniprot id: A0A143BUQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS06940
gene id: 1783515:A4E84_RS06940
uniprot id: A0A143BVT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1783515:A4E84 RS24305
gene id: 1783515:A4E84_RS24305
uniprot id: A0A143C4B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1783515:A4E84 RS11735
gene id: 1783515:A4E84_RS11735
uniprot id: A0A143BY16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1783515:A4E84 RS33670
gene id: 1783515:A4E84_RS33670
uniprot id: A0A143C9W6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS34700
gene id: 1783515:A4E84_RS34700
uniprot id: A0A143C9U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1783515:A4E84 RS38920
gene id: 1783515:A4E84_RS38920
uniprot id: A0A143CBW9
names: Similarity
messages: Belongs to the HIBADH-related family.

1783515:A4E84 RS09730
gene id: 1783515:A4E84_RS09730
uniprot id: A0A143BX05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS26570
gene id: 1783515:A4E84_RS26570
uniprot id: A0A143C6Z9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS27370
gene id: 1783515:A4E84_RS27370
uniprot id: A0A143C6U2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1783515:A4E84 RS06800
gene id: 1783515:A4E84_RS06800
uniprot id: A0A143BVS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1783515:A4E84 RS07255
gene id: 1783515:A4E84_RS07255
uniprot id: A0A143BWT7
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1783515:A4E84 RS35950
gene id: 1783515:A4E84_RS35950
uniprot id: A0A143CAF2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS25815
gene id: 1783515:A4E84_RS25815
uniprot id: A0A143C5Z0
names: Similarity
messages: Belongs to the GSP E family.

1783515:A4E84 RS33070
gene id: 1783515:A4E84_RS33070
uniprot id: A0A143C905
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS15735
gene id: 1783515:A4E84_RS15735
uniprot id: A0A143C0E6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1783515:A4E84 RS15615
gene id: 1783515:A4E84_RS15615
uniprot id: A0A143C134
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1783515:A4E84 RS22745
gene id: 1783515:A4E84_RS22745
uniprot id: A0A143C3L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS29950
gene id: 1783515:A4E84_RS29950
uniprot id: A0A143CDM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Might have a role in establishing the nucleoid structure of elementary bodies.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1783515:A4E84 RS24395
gene id: 1783515:A4E84_RS24395
uniprot id: A0A143C4I4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1783515:A4E84 RS39785
gene id: 1783515:A4E84_RS39785
uniprot id: A0A143CCA5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1783515:A4E84 RS28560
gene id: 1783515:A4E84_RS28560
uniprot id: A0A143C6R7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1783515:A4E84 RS07835
gene id: 1783515:A4E84_RS07835
uniprot id: A0A143BW84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1783515:A4E84 RS36790
gene id: 1783515:A4E84_RS36790
uniprot id: A0A143CAU1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1783515:A4E84 RS31675
gene id: 1783515:A4E84_RS31675
uniprot id: A0A143C8A0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1783515:A4E84 RS27605
gene id: 1783515:A4E84_RS27605
uniprot id: A0A143C617
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS18560
gene id: 1783515:A4E84_RS18560
uniprot id: A0A143C2L9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS05455
gene id: 1783515:A4E84_RS05455
uniprot id: A0A143BUS4
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1783515:A4E84 RS16695
gene id: 1783515:A4E84_RS16695
uniprot id: A0A143C0T4
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1783515:A4E84 RS35370
gene id: 1783515:A4E84_RS35370
uniprot id: A0A143CA37
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS37535
gene id: 1783515:A4E84_RS37535
uniprot id: A0A143CB58
names: Similarity
messages: In the N-terminal section; belongs to the cytochrome P450 family.

1783515:A4E84 RS29495
gene id: 1783515:A4E84_RS29495
uniprot id: A0A143C8I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS20790
gene id: 1783515:A4E84_RS20790
uniprot id: A0A143C2L2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS22855
gene id: 1783515:A4E84_RS22855
uniprot id: A0A143C3N4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS30125
gene id: 1783515:A4E84_RS30125
uniprot id: A0A143CF14
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1783515:A4E84 RS24540
gene id: 1783515:A4E84_RS24540
uniprot id: A0A143C4F7
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1783515:A4E84 RS07215
gene id: 1783515:A4E84_RS07215
uniprot id: A0A143BVZ8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1783515:A4E84 RS04800
gene id: 1783515:A4E84_RS04800
uniprot id: A0A143BUQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS24940
gene id: 1783515:A4E84_RS24940
uniprot id: A0A143C5K1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS10900
gene id: 1783515:A4E84_RS10900
uniprot id: A0A143BXX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1783515:A4E84 RS28720
gene id: 1783515:A4E84_RS28720
uniprot id: A0A143C7L0
names: Similarity
messages: Belongs to the UPF0102 family.

1783515:A4E84 RS20045
gene id: 1783515:A4E84_RS20045
uniprot id: A0A143C2E5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1783515:A4E84 RS38235
gene id: 1783515:A4E84_RS38235
uniprot id: A0A143CBK6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS16590
gene id: 1783515:A4E84_RS16590
uniprot id: A0A143C1T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1783515:A4E84 RS31870
gene id: 1783515:A4E84_RS31870
uniprot id: A0A143C9N4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1783515:A4E84 RS11550
gene id: 1783515:A4E84_RS11550
uniprot id: A0A143BY86
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1783515:A4E84 RS09175
gene id: 1783515:A4E84_RS09175
uniprot id: A0A143BWX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1783515:A4E84 RS33660
gene id: 1783515:A4E84_RS33660
uniprot id: A0A143C9B7
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1783515:A4E84 RS09410
gene id: 1783515:A4E84_RS09410
uniprot id: A0A143BWU4
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1783515:A4E84 RS25070
gene id: 1783515:A4E84_RS25070
uniprot id: A0A143C5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1783515:A4E84 RS03095
gene id: 1783515:A4E84_RS03095
uniprot id: A0A143BTX9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1783515:A4E84 RS39575
gene id: 1783515:A4E84_RS39575
uniprot id: A0A143CC53
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1783515:A4E84 RS25460
gene id: 1783515:A4E84_RS25460
uniprot id: A0A143C532
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1783515:A4E84 RS31125
gene id: 1783515:A4E84_RS31125
uniprot id: A0A143C7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS10725
gene id: 1783515:A4E84_RS10725
uniprot id: A0A143BXU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1783515:A4E84 RS36695
gene id: 1783515:A4E84_RS36695
uniprot id: A0A143CAR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS08030
gene id: 1783515:A4E84_RS08030
uniprot id: A0A143BW48
names: Similarity
messages: Belongs to the glutamine synthetase family.

1783515:A4E84 RS23740
gene id: 1783515:A4E84_RS23740
uniprot id: A0A143C4Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1783515:A4E84 RS10740
gene id: 1783515:A4E84_RS10740
uniprot id: A0A143BXU1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1783515:A4E84 RS16665
gene id: 1783515:A4E84_RS16665
uniprot id: A0A143C0P3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS16510
gene id: 1783515:A4E84_RS16510
uniprot id: A0A143C1M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1783515:A4E84 RS09815
gene id: 1783515:A4E84_RS09815
uniprot id: A0A143BXB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1783515:A4E84 RS26965
gene id: 1783515:A4E84_RS26965
uniprot id: A0A143C5U3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS03985
gene id: 1783515:A4E84_RS03985
uniprot id: A0A143CCN3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1783515:A4E84 RS05765
gene id: 1783515:A4E84_RS05765
uniprot id: A0A143BV96
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1783515:A4E84 RS05320
gene id: 1783515:A4E84_RS05320
uniprot id: A0A143BUZ9
names: Similarity
messages: Belongs to the DapA family.

1783515:A4E84 RS32275
gene id: 1783515:A4E84_RS32275
uniprot id: A0A143C8K8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS31485
gene id: 1783515:A4E84_RS31485
uniprot id: A0A143C875
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS04805
gene id: 1783515:A4E84_RS04805
uniprot id: A0A143BUP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS31400
gene id: 1783515:A4E84_RS31400
uniprot id: A0A143C8S8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1783515:A4E84 RS35545
gene id: 1783515:A4E84_RS35545
uniprot id: A0A143CA69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1783515:A4E84 RS18475
gene id: 1783515:A4E84_RS18475
uniprot id: A0A143C1N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1783515:A4E84 RS38730
gene id: 1783515:A4E84_RS38730
uniprot id: A0A143CC91
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS15690
gene id: 1783515:A4E84_RS15690
uniprot id: A0A143C0A3
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1783515:A4E84 RS08400
gene id: 1783515:A4E84_RS08400
uniprot id: A0A143BXG4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS36105
gene id: 1783515:A4E84_RS36105
uniprot id: A0A143CBV7
names: Similarity
messages: Belongs to the UPF0098 family.

1783515:A4E84 RS13340
gene id: 1783515:A4E84_RS13340
uniprot id: A0A143BZ24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1783515:A4E84 RS33445
gene id: 1783515:A4E84_RS33445
uniprot id: A0A143C943
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

1783515:A4E84 RS36215
gene id: 1783515:A4E84_RS36215
uniprot id: A0A143CBL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1783515:A4E84 RS32385
gene id: 1783515:A4E84_RS32385
uniprot id: A0A143C9X2
names: Subunit
messages: Homotetramer.

1783515:A4E84 RS38210
gene id: 1783515:A4E84_RS38210
uniprot id: A0A143CBI5
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1783515:A4E84 RS35750
gene id: 1783515:A4E84_RS35750
uniprot id: A0A143CBC7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS20880
gene id: 1783515:A4E84_RS20880
uniprot id: A0A143C405
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS13525
gene id: 1783515:A4E84_RS13525
uniprot id: A0A143BZ55
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1783515:A4E84 RS09210
gene id: 1783515:A4E84_RS09210
uniprot id: A0A143BWM8
names: Similarity
messages: Belongs to the peptidase S8 family.

1783515:A4E84 RS34215
gene id: 1783515:A4E84_RS34215
uniprot id: A0A143C9L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS22570
gene id: 1783515:A4E84_RS22570
uniprot id: A0A143C3P1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1783515:A4E84 RS14725
gene id: 1783515:A4E84_RS14725
uniprot id: A0A143BZY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1783515:A4E84 RS27195
gene id: 1783515:A4E84_RS27195
uniprot id: A0A143C604
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1783515:A4E84 RS34360
gene id: 1783515:A4E84_RS34360
uniprot id: A0A143C9L6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS29280
gene id: 1783515:A4E84_RS29280
uniprot id: A0A143C7R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1783515:A4E84 RS27740
gene id: 1783515:A4E84_RS27740
uniprot id: A0A143C6D4
names: Similarity
messages: Belongs to the thioredoxin family.

1783515:A4E84 RS10465
gene id: 1783515:A4E84_RS10465
uniprot id: A0A143BXP3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS03585
gene id: 1783515:A4E84_RS03585
uniprot id: A0A143BUT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1783515:A4E84 RS32390
gene id: 1783515:A4E84_RS32390
uniprot id: A0A143C8M6
names: Similarity
messages: Belongs to the allantoicase family.

1783515:A4E84 RS28625
gene id: 1783515:A4E84_RS28625
uniprot id: A0A143C6V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS07825
gene id: 1783515:A4E84_RS07825
uniprot id: A0A143BWA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1783515:A4E84 RS05460
gene id: 1783515:A4E84_RS05460
uniprot id: A0A143BVX6
names: Subcellular Location Annotation
messages: Secreted

1783515:A4E84 RS21655
gene id: 1783515:A4E84_RS21655
uniprot id: A0A143C380
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS35580
gene id: 1783515:A4E84_RS35580
uniprot id: A0A143CAU5
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1783515:A4E84 RS27565
gene id: 1783515:A4E84_RS27565
uniprot id: A0A143C6Y6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1783515:A4E84 RS20525
gene id: 1783515:A4E84_RS20525
uniprot id: A0A143C2L4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS30280
gene id: 1783515:A4E84_RS30280
uniprot id: A0A143C8F8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1783515:A4E84 RS19225
gene id: 1783515:A4E84_RS19225
uniprot id: A0A143C248
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1783515:A4E84 RS35455
gene id: 1783515:A4E84_RS35455
uniprot id: A0A143CAS6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.

1783515:A4E84 RS03575
gene id: 1783515:A4E84_RS03575
uniprot id: A0A143BTT3
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1783515:A4E84 RS17505
gene id: 1783515:A4E84_RS17505
uniprot id: A0A143C1T9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS39380
gene id: 1783515:A4E84_RS39380
uniprot id: A0A143CC55
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1783515:A4E84 RS07130
gene id: 1783515:A4E84_RS07130
uniprot id: A0A143BVK8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS10865
gene id: 1783515:A4E84_RS10865
uniprot id: A0A143BXK5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1783515:A4E84 RS22415
gene id: 1783515:A4E84_RS22415
uniprot id: A0A143C3F3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS03055
gene id: 1783515:A4E84_RS03055
uniprot id: A0A143CCF4
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS07810
gene id: 1783515:A4E84_RS07810
uniprot id: A0A143BX37
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS33950
gene id: 1783515:A4E84_RS33950
uniprot id: A0A143C9G4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS31390
gene id: 1783515:A4E84_RS31390
uniprot id: A0A143C864
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1783515:A4E84 RS01955
gene id: 1783515:A4E84_RS01955
uniprot id: A0A143BUA1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1783515:A4E84 RS28060
gene id: 1783515:A4E84_RS28060
uniprot id: A0A143C6H2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS14450
gene id: 1783515:A4E84_RS14450
uniprot id: A0A143C0G5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS31170
gene id: 1783515:A4E84_RS31170
uniprot id: A0A143C7Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

1783515:A4E84 RS10235
gene id: 1783515:A4E84_RS10235
uniprot id: A0A143BXF9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1783515:A4E84 RS13035
gene id: 1783515:A4E84_RS13035
uniprot id: A0A143BYR0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1783515:A4E84 RS24315
gene id: 1783515:A4E84_RS24315
uniprot id: A0A143C4I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1783515:A4E84 RS18565
gene id: 1783515:A4E84_RS18565
uniprot id: A0A143C2D5
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1783515:A4E84 RS31540
gene id: 1783515:A4E84_RS31540
uniprot id: A0A143C885
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1783515:A4E84 RS06185
gene id: 1783515:A4E84_RS06185
uniprot id: A0A143BV84
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS18180
gene id: 1783515:A4E84_RS18180
uniprot id: A0A143C1G7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1783515:A4E84 RS10225
gene id: 1783515:A4E84_RS10225
uniprot id: A0A143BY56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1783515:A4E84 RS29125
gene id: 1783515:A4E84_RS29125
uniprot id: A0A143C706
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1783515:A4E84 RS38465
gene id: 1783515:A4E84_RS38465
uniprot id: A0A143CCX7
names: Similarity
messages: Belongs to the YciI family.

1783515:A4E84 RS34310
gene id: 1783515:A4E84_RS34310
uniprot id: A0A143C9K6
names: Similarity
messages: Belongs to the proline racemase family.

1783515:A4E84 RS25305
gene id: 1783515:A4E84_RS25305
uniprot id: A0A143C501
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

1783515:A4E84 RS36305
gene id: 1783515:A4E84_RS36305
uniprot id: A0A143CAL1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS37030
gene id: 1783515:A4E84_RS37030
uniprot id: A0A143CBH2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS22465
gene id: 1783515:A4E84_RS22465
uniprot id: A0A143C3D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1783515:A4E84 RS10355
gene id: 1783515:A4E84_RS10355
uniprot id: A0A143BXK9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS34460
gene id: 1783515:A4E84_RS34460
uniprot id: A0A143CAA4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1783515:A4E84 RS06610
gene id: 1783515:A4E84_RS06610
uniprot id: A0A143BVL9
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1783515:A4E84 RS37320
gene id: 1783515:A4E84_RS37320
uniprot id: A0A143CB08
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS26940
gene id: 1783515:A4E84_RS26940
uniprot id: A0A143C5V4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1783515:A4E84 RS25130
gene id: 1783515:A4E84_RS25130
uniprot id: A0A143C4X0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1783515:A4E84 RS07585
gene id: 1783515:A4E84_RS07585
uniprot id: A0A143BW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS37220
gene id: 1783515:A4E84_RS37220
uniprot id: A0A143CB40
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS28275
gene id: 1783515:A4E84_RS28275
uniprot id: A0A143C6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1783515:A4E84 RS11040
gene id: 1783515:A4E84_RS11040
uniprot id: A0A143BYI6
names: Similarity
messages: Belongs to the peptidase C40 family.

1783515:A4E84 RS07085
gene id: 1783515:A4E84_RS07085
uniprot id: A0A143BWR7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1783515:A4E84 RS06370
gene id: 1783515:A4E84_RS06370
uniprot id: A0A143BW66
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS23080
gene id: 1783515:A4E84_RS23080
uniprot id: A0A143C3Y3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1783515:A4E84 RS19140
gene id: 1783515:A4E84_RS19140
uniprot id: A0A143C1X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1783515:A4E84 RS06170
gene id: 1783515:A4E84_RS06170
uniprot id: A0A143BVD9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS07775
gene id: 1783515:A4E84_RS07775
uniprot id: A0A143BW96
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS23950
gene id: 1783515:A4E84_RS23950
uniprot id: A0A143C449
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1783515:A4E84 RS24320
gene id: 1783515:A4E84_RS24320
uniprot id: A0A143C5C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1783515:A4E84 RS09360
gene id: 1783515:A4E84_RS09360
uniprot id: A0A143BWT5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1783515:A4E84 RS33240
gene id: 1783515:A4E84_RS33240
uniprot id: A0A143CDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1783515:A4E84 RS26135
gene id: 1783515:A4E84_RS26135
uniprot id: A0A143C5D9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS03190
gene id: 1783515:A4E84_RS03190
uniprot id: A0A143CCK4
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

1783515:A4E84 RS04760
gene id: 1783515:A4E84_RS04760
uniprot id: A0A143BUG5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1783515:A4E84 RS28340
gene id: 1783515:A4E84_RS28340
uniprot id: A0A143C7C7
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

1783515:A4E84 RS33075
gene id: 1783515:A4E84_RS33075
uniprot id: A0A143C922
names: Similarity
messages: Belongs to the CdaR family.

1783515:A4E84 RS16450
gene id: 1783515:A4E84_RS16450
uniprot id: A0A143C0K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1783515:A4E84 RS18660
gene id: 1783515:A4E84_RS18660
uniprot id: A0A143C1M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1783515:A4E84 RS17850
gene id: 1783515:A4E84_RS17850
uniprot id: A0A143C1B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1783515:A4E84 RS07045
gene id: 1783515:A4E84_RS07045
uniprot id: A0A143BVU6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1783515:A4E84 RS05920
gene id: 1783515:A4E84_RS05920
uniprot id: A0A143BUY0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS34570
gene id: 1783515:A4E84_RS34570
uniprot id: A0A143CAC4
names: Similarity
messages: Belongs to the YciI family.

1783515:A4E84 RS15740
gene id: 1783515:A4E84_RS15740
uniprot id: A0A143C078
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS00660
gene id: 1783515:A4E84_RS00660
uniprot id: A0A143BSF5
names: Similarity
messages: Belongs to the hyi family.

1783515:A4E84 RS21890
gene id: 1783515:A4E84_RS21890
uniprot id: A0A143C3B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1783515:A4E84 RS14760
gene id: 1783515:A4E84_RS14760
uniprot id: A0A143BZL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS31205
gene id: 1783515:A4E84_RS31205
uniprot id: A0A143C842
names: Similarity
messages: Belongs to the peptidase S8 family.

1783515:A4E84 RS09930
gene id: 1783515:A4E84_RS09930
uniprot id: A0A143BX53
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1783515:A4E84 RS05360
gene id: 1783515:A4E84_RS05360
uniprot id: A0A143BV30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

1783515:A4E84 RS06120
gene id: 1783515:A4E84_RS06120
uniprot id: A0A143BVD0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS14200
gene id: 1783515:A4E84_RS14200
uniprot id: A0A143BZ95
names: Similarity
messages: Belongs to the melC1 family.

1783515:A4E84 RS23975
gene id: 1783515:A4E84_RS23975
uniprot id: A0A143C4I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS13785
gene id: 1783515:A4E84_RS13785
uniprot id: A0A143BZ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1783515:A4E84 RS15400
gene id: 1783515:A4E84_RS15400
uniprot id: A0A143C086
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS08055
gene id: 1783515:A4E84_RS08055
uniprot id: A0A143BWE4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS29045
gene id: 1783515:A4E84_RS29045
uniprot id: A0A143C6W3
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1783515:A4E84 RS28355
gene id: 1783515:A4E84_RS28355
uniprot id: A0A143C6K1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1783515:A4E84 RS04200
gene id: 1783515:A4E84_RS04200
uniprot id: A0A143BV24
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1783515:A4E84 RS14650
gene id: 1783515:A4E84_RS14650
uniprot id: A0A143BZH8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS30855
gene id: 1783515:A4E84_RS30855
uniprot id: A0A143C8I3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1783515:A4E84 RS21510
gene id: 1783515:A4E84_RS21510
uniprot id: A0A143CAW6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1783515:A4E84 RS14270
gene id: 1783515:A4E84_RS14270
uniprot id: A0A143C0D3
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1783515:A4E84 RS33495
gene id: 1783515:A4E84_RS33495
uniprot id: A0A143C988
names: Similarity
messages: Belongs to the peptidase C56 family.

1783515:A4E84 RS04930
gene id: 1783515:A4E84_RS04930
uniprot id: A0A143BUS7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS25630
gene id: 1783515:A4E84_RS25630
uniprot id: A0A143C503
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1783515:A4E84 RS16500
gene id: 1783515:A4E84_RS16500
uniprot id: A0A143C0G9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1783515:A4E84 RS20025
gene id: 1783515:A4E84_RS20025
uniprot id: A0A143C2D2
names: Similarity
messages: Belongs to the thioredoxin family.

1783515:A4E84 RS10140
gene id: 1783515:A4E84_RS10140
uniprot id: A0A143BX93
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS22120
gene id: 1783515:A4E84_RS22120
uniprot id: A0A143C4C8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1783515:A4E84 RS33810
gene id: 1783515:A4E84_RS33810
uniprot id: A0A143C9A1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

1783515:A4E84 RS06830
gene id: 1783515:A4E84_RS06830
uniprot id: A0A143BVQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1783515:A4E84 RS17630
gene id: 1783515:A4E84_RS17630
uniprot id: A0A143C172
names: Similarity
messages: Belongs to the UPF0309 family.

1783515:A4E84 RS28190
gene id: 1783515:A4E84_RS28190
uniprot id: A0A143C795
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1783515:A4E84 RS35130
gene id: 1783515:A4E84_RS35130
uniprot id: A0A143CB22
names: Similarity
messages: Belongs to the TPP enzyme family.

1783515:A4E84 RS23710
gene id: 1783515:A4E84_RS23710
uniprot id: A0A143C487
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS34615
gene id: 1783515:A4E84_RS34615
uniprot id: A0A143C9X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1783515:A4E84 RS36765
gene id: 1783515:A4E84_RS36765
uniprot id: A0A143CBD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1783515:A4E84 RS16685
gene id: 1783515:A4E84_RS16685
uniprot id: A0A143C0R9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS34555
gene id: 1783515:A4E84_RS34555
uniprot id: A0A143C9R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1783515:A4E84 RS05620
gene id: 1783515:A4E84_RS05620
uniprot id: A0A143CCN2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1783515:A4E84 RS30545
gene id: 1783515:A4E84_RS30545
uniprot id: A0A143C8L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1783515:A4E84 RS25175
gene id: 1783515:A4E84_RS25175
uniprot id: A0A143C682
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS15900
gene id: 1783515:A4E84_RS15900
uniprot id: A0A143C0Y4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS17565
gene id: 1783515:A4E84_RS17565
uniprot id: A0A143C1B6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1783515:A4E84 RS26830
gene id: 1783515:A4E84_RS26830
uniprot id: A0A143C5T1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1783515:A4E84 RS26000
gene id: 1783515:A4E84_RS26000
uniprot id: A0A143C5H9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1783515:A4E84 RS21700
gene id: 1783515:A4E84_RS21700
uniprot id: A0A143C399
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1783515:A4E84 RS18065
gene id: 1783515:A4E84_RS18065
uniprot id: A0A143C1F1
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1783515:A4E84 RS13775
gene id: 1783515:A4E84_RS13775
uniprot id: A0A143C0B3
names: Similarity
messages: Belongs to the FPG family.

1783515:A4E84 RS26860
gene id: 1783515:A4E84_RS26860
uniprot id: A0A143C5U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS21945
gene id: 1783515:A4E84_RS21945
uniprot id: A0A143C4A5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1783515:A4E84 RS06085
gene id: 1783515:A4E84_RS06085
uniprot id: A0A143BV16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS15160
gene id: 1783515:A4E84_RS15160
uniprot id: A0A143BZS9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1783515:A4E84 RS23725
gene id: 1783515:A4E84_RS23725
uniprot id: A0A143C424
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

1783515:A4E84 RS27020
gene id: 1783515:A4E84_RS27020
uniprot id: A0A143C5X7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1783515:A4E84 RS29295
gene id: 1783515:A4E84_RS29295
uniprot id: A0A143C714
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1783515:A4E84 RS07725
gene id: 1783515:A4E84_RS07725
uniprot id: A0A143BW77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1783515:A4E84 RS07095
gene id: 1783515:A4E84_RS07095
uniprot id: A0A143BVY1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1783515:A4E84 RS10805
gene id: 1783515:A4E84_RS10805
uniprot id: A0A143BXM1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1783515:A4E84 RS13680
gene id: 1783515:A4E84_RS13680
uniprot id: A0A143BZU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1783515:A4E84 RS24870
gene id: 1783515:A4E84_RS24870
uniprot id: A0A143C4P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1783515:A4E84 RS28610
gene id: 1783515:A4E84_RS28610
uniprot id: A0A143C6S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1783515:A4E84 RS15245
gene id: 1783515:A4E84_RS15245
uniprot id: A0A143C020
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS03630
gene id: 1783515:A4E84_RS03630
uniprot id: A0A143BV10
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1783515:A4E84 RS31515
gene id: 1783515:A4E84_RS31515
uniprot id: A0A143C892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS42615
gene id: 1783515:A4E84_RS42615
uniprot id: A0A143CAL2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1783515:A4E84 RS01875
gene id: 1783515:A4E84_RS01875
uniprot id: A0A143BU77
names: Similarity
messages: Belongs to the NodU/CmcH family.

1783515:A4E84 RS34435
gene id: 1783515:A4E84_RS34435
uniprot id: A0A143C9P6
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

1783515:A4E84 RS26805
gene id: 1783515:A4E84_RS26805
uniprot id: A0A143C5R3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1783515:A4E84 RS12895
gene id: 1783515:A4E84_RS12895
uniprot id: A0A143BZ03
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS07245
gene id: 1783515:A4E84_RS07245
uniprot id: A0A143BVN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1783515:A4E84 RS39235
gene id: 1783515:A4E84_RS39235
uniprot id: A0A143CD20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

1783515:A4E84 RS02360
gene id: 1783515:A4E84_RS02360
uniprot id: A0A143CDG9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1783515:A4E84 RS09820
gene id: 1783515:A4E84_RS09820
uniprot id: A0A143BY80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1783515:A4E84 RS07345
gene id: 1783515:A4E84_RS07345
uniprot id: A0A143BVP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1783515:A4E84 RS03920
gene id: 1783515:A4E84_RS03920
uniprot id: A0A143BV58
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1783515:A4E84 RS24575
gene id: 1783515:A4E84_RS24575
uniprot id: A0A143C4L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1783515:A4E84 RS26455
gene id: 1783515:A4E84_RS26455
uniprot id: A0A143C5K9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS18120
gene id: 1783515:A4E84_RS18120
uniprot id: A0A143C1G8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1783515:A4E84 RS37740
gene id: 1783515:A4E84_RS37740
uniprot id: A0A143CBA0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS25800
gene id: 1783515:A4E84_RS25800
uniprot id: A0A143C567
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS08580
gene id: 1783515:A4E84_RS08580
uniprot id: A0A143BXJ4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS23750
gene id: 1783515:A4E84_RS23750
uniprot id: A0A143C495
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS04420
gene id: 1783515:A4E84_RS04420
uniprot id: A0A143BV64
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1783515:A4E84 RS06455
gene id: 1783515:A4E84_RS06455
uniprot id: A0A143BVD1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS24725
gene id: 1783515:A4E84_RS24725
uniprot id: A0A143C4W1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS00945
gene id: 1783515:A4E84_RS00945
uniprot id: A0A143BSJ8
names: Similarity
messages: Belongs to the group II decarboxylase family.

1783515:A4E84 RS13335
gene id: 1783515:A4E84_RS13335
uniprot id: A0A143BZ17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1783515:A4E84 RS17490
gene id: 1783515:A4E84_RS17490
uniprot id: A0A143CEH7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1783515:A4E84 RS30815
gene id: 1783515:A4E84_RS30815
uniprot id: A0A143C7X6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1783515:A4E84 RS39590
gene id: 1783515:A4E84_RS39590
uniprot id: A0A143CD70
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS13135
gene id: 1783515:A4E84_RS13135
uniprot id: A0A143BYR5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1783515:A4E84 RS27705
gene id: 1783515:A4E84_RS27705
uniprot id: A0A143C7L2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS09380
gene id: 1783515:A4E84_RS09380
uniprot id: A0A143BX52
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS18755
gene id: 1783515:A4E84_RS18755
uniprot id: A0A143C2W0
names: Similarity
messages: Belongs to the PstS family.

1783515:A4E84 RS37240
gene id: 1783515:A4E84_RS37240
uniprot id: A0A143CB00
names: Similarity
messages: Belongs to the glutamine synthetase family.

1783515:A4E84 RS20740
gene id: 1783515:A4E84_RS20740
uniprot id: A0A143C2P0
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

1783515:A4E84 RS31045
gene id: 1783515:A4E84_RS31045
uniprot id: A0A143C812
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS31550
gene id: 1783515:A4E84_RS31550
uniprot id: A0A143C8A1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS22720
gene id: 1783515:A4E84_RS22720
uniprot id: A0A143C3T8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS18025
gene id: 1783515:A4E84_RS18025
uniprot id: A0A143C1E8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1783515:A4E84 RS12590
gene id: 1783515:A4E84_RS12590
uniprot id: A0A143BYH9
names: Similarity
messages: Belongs to the YciI family.

1783515:A4E84 RS07435
gene id: 1783515:A4E84_RS07435
uniprot id: A0A143BW16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1783515:A4E84 RS16190
gene id: 1783515:A4E84_RS16190
uniprot id: A0A143C0K1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1783515:A4E84 RS02535
gene id: 1783515:A4E84_RS02535
uniprot id: A0A143BTE7
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1783515:A4E84 RS26035
gene id: 1783515:A4E84_RS26035
uniprot id: A0A143C5E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1783515:A4E84 RS35355
gene id: 1783515:A4E84_RS35355
uniprot id: A0A143CB61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1783515:A4E84 RS26910
gene id: 1783515:A4E84_RS26910
uniprot id: A0A143C5V8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1783515:A4E84 RS21350
gene id: 1783515:A4E84_RS21350
uniprot id: A0A143C3Z4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS34455
gene id: 1783515:A4E84_RS34455
uniprot id: A0A143C9U4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1783515:A4E84 RS11340
gene id: 1783515:A4E84_RS11340
uniprot id: A0A143BZ32
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1783515:A4E84 RS21910
gene id: 1783515:A4E84_RS21910
uniprot id: A0A143C3F5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS24740
gene id: 1783515:A4E84_RS24740
uniprot id: A0A143C4Q5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS25560
gene id: 1783515:A4E84_RS25560
uniprot id: A0A143C529
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1783515:A4E84 RS17580
gene id: 1783515:A4E84_RS17580
uniprot id: A0A143C171
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1783515:A4E84 RS28270
gene id: 1783515:A4E84_RS28270
uniprot id: A0A143C6C3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS13675
gene id: 1783515:A4E84_RS13675
uniprot id: A0A143C046
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1783515:A4E84 RS38075
gene id: 1783515:A4E84_RS38075
uniprot id: A0A143CBF5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1783515:A4E84 RS35785
gene id: 1783515:A4E84_RS35785
uniprot id: A0A143CAC5
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

1783515:A4E84 RS34625
gene id: 1783515:A4E84_RS34625
uniprot id: A0A143CAR0
names: Similarity
messages: Belongs to the arginase family.

1783515:A4E84 RS26840
gene id: 1783515:A4E84_RS26840
uniprot id: A0A143C5Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1783515:A4E84 RS23370
gene id: 1783515:A4E84_RS23370
uniprot id: A0A143C3X0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS09195
gene id: 1783515:A4E84_RS09195
uniprot id: A0A143BWQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1783515:A4E84 RS07390
gene id: 1783515:A4E84_RS07390
uniprot id: A0A143BVT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS05245
gene id: 1783515:A4E84_RS05245
uniprot id: A0A143BVT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1783515:A4E84 RS17545
gene id: 1783515:A4E84_RS17545
uniprot id: A0A143C0Y7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS24075
gene id: 1783515:A4E84_RS24075
uniprot id: A0A143C5Q4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS03605
gene id: 1783515:A4E84_RS03605
uniprot id: A0A143BU69
names: Similarity
messages: Belongs to the UPF0166 family.

1783515:A4E84 RS06930
gene id: 1783515:A4E84_RS06930
uniprot id: A0A143CCT1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS26120
gene id: 1783515:A4E84_RS26120
uniprot id: A0A143C5J8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1783515:A4E84 RS26340
gene id: 1783515:A4E84_RS26340
uniprot id: A0A143C5N0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1783515:A4E84 RS34815
gene id: 1783515:A4E84_RS34815
uniprot id: A0A143CDW5
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1783515:A4E84 RS29635
gene id: 1783515:A4E84_RS29635
uniprot id: A0A143C7C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1783515:A4E84 RS05150
gene id: 1783515:A4E84_RS05150
uniprot id: A0A143BVV7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS10765
gene id: 1783515:A4E84_RS10765
uniprot id: A0A143BYN6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS10285
gene id: 1783515:A4E84_RS10285
uniprot id: A0A143BXK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1783515:A4E84 RS15895
gene id: 1783515:A4E84_RS15895
uniprot id: A0A143C179
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24895
gene id: 1783515:A4E84_RS24895
uniprot id: A0A143C4U1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1783515:A4E84 RS24440
gene id: 1783515:A4E84_RS24440
uniprot id: A0A143C4R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1783515:A4E84 RS30465
gene id: 1783515:A4E84_RS30465
uniprot id: A0A143C7N0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1783515:A4E84 RS30005
gene id: 1783515:A4E84_RS30005
uniprot id: A0A143C8A9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1783515:A4E84 RS14015
gene id: 1783515:A4E84_RS14015
uniprot id: A0A143BZ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1783515:A4E84 RS19930
gene id: 1783515:A4E84_RS19930
uniprot id: A0A143C315
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1783515:A4E84 RS08375
gene id: 1783515:A4E84_RS08375
uniprot id: A0A143CDT4
names: Similarity
messages: Belongs to the UPF0225 family.

1783515:A4E84 RS30055
gene id: 1783515:A4E84_RS30055
uniprot id: A0A143C8C0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS24330
gene id: 1783515:A4E84_RS24330
uniprot id: A0A143C5A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1783515:A4E84 RS14445
gene id: 1783515:A4E84_RS14445
uniprot id: A0A143BZH6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1783515:A4E84 RS28955
gene id: 1783515:A4E84_RS28955
uniprot id: A0A143C7K3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS08830
gene id: 1783515:A4E84_RS08830
uniprot id: A0A143BWU5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS19180
gene id: 1783515:A4E84_RS19180
uniprot id: A0A143C1Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1783515:A4E84 RS14765
gene id: 1783515:A4E84_RS14765
uniprot id: A0A143BZN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS08795
gene id: 1783515:A4E84_RS08795
uniprot id: A0A143BXN4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1783515:A4E84 RS04990
gene id: 1783515:A4E84_RS04990
uniprot id: A0A143BVS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS09600
gene id: 1783515:A4E84_RS09600
uniprot id: A0A143BX50
names: Similarity
messages: Belongs to the AHA1 family.

1783515:A4E84 RS09365
gene id: 1783515:A4E84_RS09365
uniprot id: A0A143BWQ6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1783515:A4E84 RS25905
gene id: 1783515:A4E84_RS25905
uniprot id: A0A143C6N0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS30470
gene id: 1783515:A4E84_RS30470
uniprot id: A0A143C901
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1783515:A4E84 RS01100
gene id: 1783515:A4E84_RS01100
uniprot id: A0A143BT03
names: Similarity
messages: Belongs to the NodU/CmcH family.

1783515:A4E84 RS33685
gene id: 1783515:A4E84_RS33685
uniprot id: A0A143C9B8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS24265
gene id: 1783515:A4E84_RS24265
uniprot id: A0A143C4G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1783515:A4E84 RS26740
gene id: 1783515:A4E84_RS26740
uniprot id: A0A143C5J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS09710
gene id: 1783515:A4E84_RS09710
uniprot id: A0A143BX64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1783515:A4E84 RS20065
gene id: 1783515:A4E84_RS20065
uniprot id: A0A143C250
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1783515:A4E84 RS35470
gene id: 1783515:A4E84_RS35470
uniprot id: A0A143CA71
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1783515:A4E84 RS35665
gene id: 1783515:A4E84_RS35665
uniprot id: A0A143CBP1
names: Similarity
messages: Belongs to the FPG family.

1783515:A4E84 RS27440
gene id: 1783515:A4E84_RS27440
uniprot id: A0A143C631
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1783515:A4E84 RS11285
gene id: 1783515:A4E84_RS11285
uniprot id: A0A143BXV5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1783515:A4E84 RS10755
gene id: 1783515:A4E84_RS10755
uniprot id: A0A143BXL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

1783515:A4E84 RS07760
gene id: 1783515:A4E84_RS07760
uniprot id: A0A143BX26
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS27335
gene id: 1783515:A4E84_RS27335
uniprot id: A0A143C623
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1783515:A4E84 RS06080
gene id: 1783515:A4E84_RS06080
uniprot id: A0A143BV66
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1783515:A4E84 RS27130
gene id: 1783515:A4E84_RS27130
uniprot id: A0A143C6P1
names: Similarity
messages: Belongs to the peptidase C40 family.

1783515:A4E84 RS28200
gene id: 1783515:A4E84_RS28200
uniprot id: A0A143C6H9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1783515:A4E84 RS18665
gene id: 1783515:A4E84_RS18665
uniprot id: A0A143C2N6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1783515:A4E84 RS13455
gene id: 1783515:A4E84_RS13455
uniprot id: A0A143BZ36
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1783515:A4E84 RS22055
gene id: 1783515:A4E84_RS22055
uniprot id: A0A143C3E0
names: Subunit
messages: Homodimer.

1783515:A4E84 RS34210
gene id: 1783515:A4E84_RS34210
uniprot id: A0A143C9I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS24600
gene id: 1783515:A4E84_RS24600
uniprot id: A0A143C4M3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS08275
gene id: 1783515:A4E84_RS08275
uniprot id: A0A143BWI3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS08575
gene id: 1783515:A4E84_RS08575
uniprot id: A0A143CE30
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS11080
gene id: 1783515:A4E84_RS11080
uniprot id: A0A143CCX9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS39180
gene id: 1783515:A4E84_RS39180
uniprot id: A0A143CC01
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1783515:A4E84 RS18085
gene id: 1783515:A4E84_RS18085
uniprot id: A0A143C170
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1783515:A4E84 RS20810
gene id: 1783515:A4E84_RS20810
uniprot id: A0A143C2Z0
names: Similarity
messages: Belongs to the LOR family.

1783515:A4E84 RS26750
gene id: 1783515:A4E84_RS26750
uniprot id: A0A143C5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS11955
gene id: 1783515:A4E84_RS11955
uniprot id: A0A143BYG1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS30835
gene id: 1783515:A4E84_RS30835
uniprot id: A0A143C961
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1783515:A4E84 RS04480
gene id: 1783515:A4E84_RS04480
uniprot id: A0A143BV76
names: Similarity
messages: Belongs to the CdaR family.

1783515:A4E84 RS12620
gene id: 1783515:A4E84_RS12620
uniprot id: A0A143BYP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS01060
gene id: 1783515:A4E84_RS01060
uniprot id: A0A143BSL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS09415
gene id: 1783515:A4E84_RS09415
uniprot id: A0A143BWS6
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1783515:A4E84 RS06355
gene id: 1783515:A4E84_RS06355
uniprot id: A0A143BV72
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS26420
gene id: 1783515:A4E84_RS26420
uniprot id: A0A143C5E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1783515:A4E84 RS23360
gene id: 1783515:A4E84_RS23360
uniprot id: A0A143C5D6
names: Similarity
messages: Belongs to the UbiD family.

1783515:A4E84 RS15480
gene id: 1783515:A4E84_RS15480
uniprot id: A0A143BZX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1783515:A4E84 RS13130
gene id: 1783515:A4E84_RS13130
uniprot id: A0A143BZZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS13320
gene id: 1783515:A4E84_RS13320
uniprot id: A0A143BZY3
names: Similarity
messages: Belongs to the DapA family.

1783515:A4E84 RS08225
gene id: 1783515:A4E84_RS08225
uniprot id: A0A143BWF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1783515:A4E84 RS11615
gene id: 1783515:A4E84_RS11615
uniprot id: A0A143BZ78
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS15550
gene id: 1783515:A4E84_RS15550
uniprot id: A0A143C122
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS10090
gene id: 1783515:A4E84_RS10090
uniprot id: A0A143BX57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1783515:A4E84 RS05845
gene id: 1783515:A4E84_RS05845
uniprot id: A0A143BV82
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1783515:A4E84 RS33510
gene id: 1783515:A4E84_RS33510
uniprot id: A0A143C953
names: Similarity
messages: Belongs to the TPP enzyme family.

1783515:A4E84 RS30585
gene id: 1783515:A4E84_RS30585
uniprot id: A0A143C7S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1783515:A4E84 RS27340
gene id: 1783515:A4E84_RS27340
uniprot id: A0A143C5Z9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1783515:A4E84 RS31040
gene id: 1783515:A4E84_RS31040
uniprot id: A0A143C7Y0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1783515:A4E84 RS33035
gene id: 1783515:A4E84_RS33035
uniprot id: A0A143C911
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1783515:A4E84 RS19925
gene id: 1783515:A4E84_RS19925
uniprot id: A0A143C385
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS28455
gene id: 1783515:A4E84_RS28455
uniprot id: A0A143C6K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1783515:A4E84 RS26705
gene id: 1783515:A4E84_RS26705
uniprot id: A0A143C6J0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS07355
gene id: 1783515:A4E84_RS07355
uniprot id: A0A143BWW0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1783515:A4E84 RS32975
gene id: 1783515:A4E84_RS32975
uniprot id: A0A143C8Z6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1783515:A4E84 RS19980
gene id: 1783515:A4E84_RS19980
uniprot id: A0A143C393
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1783515:A4E84 RS24340
gene id: 1783515:A4E84_RS24340
uniprot id: A0A143C4J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1783515:A4E84 RS39485
gene id: 1783515:A4E84_RS39485
uniprot id: A0A143CC66
names: Similarity
messages: Belongs to the barstar family.

1783515:A4E84 RS28120
gene id: 1783515:A4E84_RS28120
uniprot id: A0A143C6I2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1783515:A4E84 RS22245
gene id: 1783515:A4E84_RS22245
uniprot id: A0A143C3C7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1783515:A4E84 RS09530
gene id: 1783515:A4E84_RS09530
uniprot id: A0A143BXS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1783515:A4E84 RS08105
gene id: 1783515:A4E84_RS08105
uniprot id: A0A143BX41
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1783515:A4E84 RS05725
gene id: 1783515:A4E84_RS05725
uniprot id: A0A143CCQ2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS07565
gene id: 1783515:A4E84_RS07565
uniprot id: A0A143CDS4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1783515:A4E84 RS08140
gene id: 1783515:A4E84_RS08140
uniprot id: A0A143BW51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1783515:A4E84 RS04560
gene id: 1783515:A4E84_RS04560
uniprot id: A0A143BUL7
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

1783515:A4E84 RS24185
gene id: 1783515:A4E84_RS24185
uniprot id: A0A143C5R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1783515:A4E84 RS35380
gene id: 1783515:A4E84_RS35380
uniprot id: A0A143CBI9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS34330
gene id: 1783515:A4E84_RS34330
uniprot id: A0A143CB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS05720
gene id: 1783515:A4E84_RS05720
uniprot id: A0A143BW57
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1783515:A4E84 RS11725
gene id: 1783515:A4E84_RS11725
uniprot id: A0A143BY33
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1783515:A4E84 RS15825
gene id: 1783515:A4E84_RS15825
uniprot id: A0A143C169
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1783515:A4E84 RS18035
gene id: 1783515:A4E84_RS18035
uniprot id: A0A143C158
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1783515:A4E84 RS23965
gene id: 1783515:A4E84_RS23965
uniprot id: A0A143C574
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1783515:A4E84 RS22985
gene id: 1783515:A4E84_RS22985
uniprot id: A0A143C429
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1783515:A4E84 RS32095
gene id: 1783515:A4E84_RS32095
uniprot id: A0A143C9R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1783515:A4E84 RS14665
gene id: 1783515:A4E84_RS14665
uniprot id: A0A143C0K6
names: Similarity
messages: Belongs to the group II decarboxylase family.

1783515:A4E84 RS14675
gene id: 1783515:A4E84_RS14675
uniprot id: A0A143BZX1
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1783515:A4E84 RS31520
gene id: 1783515:A4E84_RS31520
uniprot id: A0A143C866
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS27775
gene id: 1783515:A4E84_RS27775
uniprot id: A0A143C639
names: Similarity
messages: Belongs to the peptidase S8 family.

1783515:A4E84 RS25700
gene id: 1783515:A4E84_RS25700
uniprot id: A0A143C613
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS31050
gene id: 1783515:A4E84_RS31050
uniprot id: A0A143C7X4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1783515:A4E84 RS22875
gene id: 1783515:A4E84_RS22875
uniprot id: A0A143C4J6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS39345
gene id: 1783515:A4E84_RS39345
uniprot id: A0A143CCL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS19690
gene id: 1783515:A4E84_RS19690
uniprot id: A0A143C268
names: Similarity
messages: Belongs to the SCO1/2 family.

1783515:A4E84 RS20535
gene id: 1783515:A4E84_RS20535
uniprot id: A0A143C3B8
names: Similarity
messages: Belongs to the UPF0749 family.

1783515:A4E84 RS27630
gene id: 1783515:A4E84_RS27630
uniprot id: A0A143C6B9
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1783515:A4E84 RS19760
gene id: 1783515:A4E84_RS19760
uniprot id: A0A143C2Y7
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1783515:A4E84 RS25150
gene id: 1783515:A4E84_RS25150
uniprot id: A0A143CDI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1783515:A4E84 RS34785
gene id: 1783515:A4E84_RS34785
uniprot id: A0A143C9U6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1783515:A4E84 RS29165
gene id: 1783515:A4E84_RS29165
uniprot id: A0A143C742
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1783515:A4E84 RS31860
gene id: 1783515:A4E84_RS31860
uniprot id: A0A143C8E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS15015
gene id: 1783515:A4E84_RS15015
uniprot id: A0A143BZW0
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

1783515:A4E84 RS19820
gene id: 1783515:A4E84_RS19820
uniprot id: A0A143C2A1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1783515:A4E84 RS00430
gene id: 1783515:A4E84_RS00430
uniprot id: A0A143BSG5
names: Similarity
messages: Belongs to the UPF0167 family.

1783515:A4E84 RS29000
gene id: 1783515:A4E84_RS29000
uniprot id: A0A143C6Y9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS27865
gene id: 1783515:A4E84_RS27865
uniprot id: A0A143C6B2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1783515:A4E84 RS27610
gene id: 1783515:A4E84_RS27610
uniprot id: A0A143C676
names: Similarity
messages: Belongs to the UPF0045 family.

1783515:A4E84 RS14700
gene id: 1783515:A4E84_RS14700
uniprot id: A0A143BZJ0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS30330
gene id: 1783515:A4E84_RS30330
uniprot id: A0A143C878
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS33840
gene id: 1783515:A4E84_RS33840
uniprot id: A0A143C9F8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS25075
gene id: 1783515:A4E84_RS25075
uniprot id: A0A143C5L9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS35895
gene id: 1783515:A4E84_RS35895
uniprot id: A0A143CAE2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS22910
gene id: 1783515:A4E84_RS22910
uniprot id: A0A143C3L3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1783515:A4E84 RS24590
gene id: 1783515:A4E84_RS24590
uniprot id: A0A143C4G7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS31885
gene id: 1783515:A4E84_RS31885
uniprot id: A0A143CF38
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS23580
gene id: 1783515:A4E84_RS23580
uniprot id: A0A143CDW8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS16505
gene id: 1783515:A4E84_RS16505
uniprot id: A0A143C0L3
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS03310
gene id: 1783515:A4E84_RS03310
uniprot id: A0A143CCH0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1783515:A4E84 RS31695
gene id: 1783515:A4E84_RS31695
uniprot id: A0A143C9K9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1783515:A4E84 RS16080
gene id: 1783515:A4E84_RS16080
uniprot id: A0A143C0I3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS09575
gene id: 1783515:A4E84_RS09575
uniprot id: A0A143BWW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS28665
gene id: 1783515:A4E84_RS28665
uniprot id: A0A143C7G7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1783515:A4E84 RS03205
gene id: 1783515:A4E84_RS03205
uniprot id: A0A143CCI0
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS19895
gene id: 1783515:A4E84_RS19895
uniprot id: A0A143C2B1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS39100
gene id: 1783515:A4E84_RS39100
uniprot id: A0A143CBX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS05450
gene id: 1783515:A4E84_RS05450
uniprot id: A0A143BUR4
names: Subcellular Location Annotation
messages: Secreted

1783515:A4E84 RS10470
gene id: 1783515:A4E84_RS10470
uniprot id: A0A143CE50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
messages: Belongs to the glycosyl hydrolase 46 family.
messages: Secreted

1783515:A4E84 RS05880
gene id: 1783515:A4E84_RS05880
uniprot id: A0A143BW56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS07445
gene id: 1783515:A4E84_RS07445
uniprot id: A0A143BVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1783515:A4E84 RS27330
gene id: 1783515:A4E84_RS27330
uniprot id: A0A143C618
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1783515:A4E84 RS24325
gene id: 1783515:A4E84_RS24325
uniprot id: A0A143CDF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1783515:A4E84 RS09405
gene id: 1783515:A4E84_RS09405
uniprot id: A0A143BWU6
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1783515:A4E84 RS05910
gene id: 1783515:A4E84_RS05910
uniprot id: A0A143BW89
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

1783515:A4E84 RS33930
gene id: 1783515:A4E84_RS33930
uniprot id: A0A143C9C1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1783515:A4E84 RS11520
gene id: 1783515:A4E84_RS11520
uniprot id: A0A143CDD4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1783515:A4E84 RS30270
gene id: 1783515:A4E84_RS30270
uniprot id: A0A143C7M5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS11590
gene id: 1783515:A4E84_RS11590
uniprot id: A0A143BYT5
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS05695
gene id: 1783515:A4E84_RS05695
uniprot id: A0A143BVU3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS18550
gene id: 1783515:A4E84_RS18550
uniprot id: A0A143C1G6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS27405
gene id: 1783515:A4E84_RS27405
uniprot id: A0A143C635
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1783515:A4E84 RS30300
gene id: 1783515:A4E84_RS30300
uniprot id: A0A143C7K9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1783515:A4E84 RS13375
gene id: 1783515:A4E84_RS13375
uniprot id: A0A143BZZ5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1783515:A4E84 RS31915
gene id: 1783515:A4E84_RS31915
uniprot id: A0A143C8F4
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1783515:A4E84 RS03940
gene id: 1783515:A4E84_RS03940
uniprot id: A0A143BUB3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1783515:A4E84 RS36450
gene id: 1783515:A4E84_RS36450
uniprot id: A0A143CDX2
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

1783515:A4E84 RS38065
gene id: 1783515:A4E84_RS38065
uniprot id: A0A143CCF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS21095
gene id: 1783515:A4E84_RS21095
uniprot id: A0A143C2X4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS10020
gene id: 1783515:A4E84_RS10020
uniprot id: A0A143BXF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1783515:A4E84 RS38480
gene id: 1783515:A4E84_RS38480
uniprot id: A0A143CBM0
names: Similarity
messages: Belongs to the group II decarboxylase family.

1783515:A4E84 RS25300
gene id: 1783515:A4E84_RS25300
uniprot id: A0A143C4W3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1783515:A4E84 RS07235
gene id: 1783515:A4E84_RS07235
uniprot id: A0A143BWV6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS20080
gene id: 1783515:A4E84_RS20080
uniprot id: A0A143C3B3
names: Similarity
messages: Belongs to the UPF0232 family.

1783515:A4E84 RS01225
gene id: 1783515:A4E84_RS01225
uniprot id: A0A143BSP2
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.

1783515:A4E84 RS03930
gene id: 1783515:A4E84_RS03930
uniprot id: A0A143BUC6
names: Similarity
messages: Belongs to the HypD family.

1783515:A4E84 RS24480
gene id: 1783515:A4E84_RS24480
uniprot id: A0A143CDH1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS17650
gene id: 1783515:A4E84_RS17650
uniprot id: A0A143C0Z1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1783515:A4E84 RS22705
gene id: 1783515:A4E84_RS22705
uniprot id: A0A143C4K8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1783515:A4E84 RS12250
gene id: 1783515:A4E84_RS12250
uniprot id: A0A143BYK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS18690
gene id: 1783515:A4E84_RS18690
uniprot id: A0A143C1S3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS29290
gene id: 1783515:A4E84_RS29290
uniprot id: A0A143C758
names: Similarity
messages: Belongs to the peptidase M16 family.

1783515:A4E84 RS04475
gene id: 1783515:A4E84_RS04475
uniprot id: A0A143BVE7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS11705
gene id: 1783515:A4E84_RS11705
uniprot id: A0A143BY85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1783515:A4E84 RS04230
gene id: 1783515:A4E84_RS04230
uniprot id: A0A143BU81
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS08215
gene id: 1783515:A4E84_RS08215
uniprot id: A0A143BWH7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1783515:A4E84 RS34000
gene id: 1783515:A4E84_RS34000
uniprot id: A0A143C9F3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1783515:A4E84 RS10600
gene id: 1783515:A4E84_RS10600
uniprot id: A0A143BXG0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1783515:A4E84 RS23405
gene id: 1783515:A4E84_RS23405
uniprot id: A0A143C444
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS27680
gene id: 1783515:A4E84_RS27680
uniprot id: A0A143C6C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS20675
gene id: 1783515:A4E84_RS20675
uniprot id: A0A143C3W9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1783515:A4E84 RS16005
gene id: 1783515:A4E84_RS16005
uniprot id: A0A143C0A8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1783515:A4E84 RS29975
gene id: 1783515:A4E84_RS29975
uniprot id: A0A143C7D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1783515:A4E84 RS06180
gene id: 1783515:A4E84_RS06180
uniprot id: A0A143BWD6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS08970
gene id: 1783515:A4E84_RS08970
uniprot id: A0A143BWK6
names: Similarity
messages: Belongs to the TlyA family.

1783515:A4E84 RS01155
gene id: 1783515:A4E84_RS01155
uniprot id: A0A143BTV4
names: Similarity
messages: Belongs to the group II decarboxylase family.

1783515:A4E84 RS22750
gene id: 1783515:A4E84_RS22750
uniprot id: A0A143C3R7
names: Subcellular Location Annotation
messages: Mitochondrion

1783515:A4E84 RS28765
gene id: 1783515:A4E84_RS28765
uniprot id: A0A143CDM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1783515:A4E84 RS23755
gene id: 1783515:A4E84_RS23755
uniprot id: A0A143C471
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS10455
gene id: 1783515:A4E84_RS10455
uniprot id: A0A143BXL9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS36745
gene id: 1783515:A4E84_RS36745
uniprot id: A0A143CC51
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1783515:A4E84 RS33170
gene id: 1783515:A4E84_RS33170
uniprot id: A0A143C928
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS30960
gene id: 1783515:A4E84_RS30960
uniprot id: A0A143C7X9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

1783515:A4E84 RS21810
gene id: 1783515:A4E84_RS21810
uniprot id: A0A143C390
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS12455
gene id: 1783515:A4E84_RS12455
uniprot id: A0A143BYR4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1783515:A4E84 RS38515
gene id: 1783515:A4E84_RS38515
uniprot id: A0A143CFH1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS30175
gene id: 1783515:A4E84_RS30175
uniprot id: A0A143C7F7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS31175
gene id: 1783515:A4E84_RS31175
uniprot id: A0A143C9C3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1783515:A4E84 RS11970
gene id: 1783515:A4E84_RS11970
uniprot id: A0A143BY79
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS09920
gene id: 1783515:A4E84_RS09920
uniprot id: A0A143BXD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1783515:A4E84 RS28490
gene id: 1783515:A4E84_RS28490
uniprot id: A0A143C6K4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1783515:A4E84 RS06045
gene id: 1783515:A4E84_RS06045
uniprot id: A0A143BW04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1783515:A4E84 RS32520
gene id: 1783515:A4E84_RS32520
uniprot id: A0A143C9A3
names: Subcellular Location Annotation
messages: Cytoplasm

1783515:A4E84 RS14125
gene id: 1783515:A4E84_RS14125
uniprot id: A0A143BZ84
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS33620
gene id: 1783515:A4E84_RS33620
uniprot id: A0A143CA80
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1783515:A4E84 RS12265
gene id: 1783515:A4E84_RS12265
uniprot id: A0A143BYC8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1783515:A4E84 RS30900
gene id: 1783515:A4E84_RS30900
uniprot id: A0A143C7Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS00840
gene id: 1783515:A4E84_RS00840
uniprot id: A0A143BSH9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1783515:A4E84 RS13395
gene id: 1783515:A4E84_RS13395
uniprot id: A0A143BZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1783515:A4E84 RS16245
gene id: 1783515:A4E84_RS16245
uniprot id: A0A143CDK0
names: Similarity
messages: Belongs to the CFA/CMAS family.

1783515:A4E84 RS20805
gene id: 1783515:A4E84_RS20805
uniprot id: A0A143C3G9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1783515:A4E84 RS27010
gene id: 1783515:A4E84_RS27010
uniprot id: A0A143C5P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS14040
gene id: 1783515:A4E84_RS14040
uniprot id: A0A143BZD8
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1783515:A4E84 RS07290
gene id: 1783515:A4E84_RS07290
uniprot id: A0A143BVR9
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1783515:A4E84 RS09720
gene id: 1783515:A4E84_RS09720
uniprot id: A0A143BY60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1783515:A4E84 RS10520
gene id: 1783515:A4E84_RS10520
uniprot id: A0A143BXM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1783515:A4E84 RS16035
gene id: 1783515:A4E84_RS16035
uniprot id: A0A143C0F8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1783515:A4E84 RS14310
gene id: 1783515:A4E84_RS14310
uniprot id: A0A143BZB5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS07330
gene id: 1783515:A4E84_RS07330
uniprot id: A0A143BVZ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1783515:A4E84 RS25525
gene id: 1783515:A4E84_RS25525
uniprot id: A0A143C5Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1783515:A4E84 RS33210
gene id: 1783515:A4E84_RS33210
uniprot id: A0A143C931
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1783515:A4E84 RS35305
gene id: 1783515:A4E84_RS35305
uniprot id: A0A143CA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1783515:A4E84 RS08990
gene id: 1783515:A4E84_RS08990
uniprot id: A0A143BWX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1783515:A4E84 RS09170
gene id: 1783515:A4E84_RS09170
uniprot id: A0A143BX10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS38435
gene id: 1783515:A4E84_RS38435
uniprot id: A0A143CBL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1783515:A4E84 RS01350
gene id: 1783515:A4E84_RS01350
uniprot id: A0A143BSR1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS10720
gene id: 1783515:A4E84_RS10720
uniprot id: A0A143BYC6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1783515:A4E84 RS05060
gene id: 1783515:A4E84_RS05060
uniprot id: A0A143BUJ4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1783515:A4E84 RS33195
gene id: 1783515:A4E84_RS33195
uniprot id: A0A143C9L7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1783515:A4E84 RS05215
gene id: 1783515:A4E84_RS05215
uniprot id: A0A143BUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

1783515:A4E84 RS02310
gene id: 1783515:A4E84_RS02310
uniprot id: A0A143BT75
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS05705
gene id: 1783515:A4E84_RS05705
uniprot id: A0A143BV87
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1783515:A4E84 RS26215
gene id: 1783515:A4E84_RS26215
uniprot id: A0A143C5H0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1783515:A4E84 RS21785
gene id: 1783515:A4E84_RS21785
uniprot id: A0A143C397
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS18090
gene id: 1783515:A4E84_RS18090
uniprot id: A0A143C181
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1783515:A4E84 RS21535
gene id: 1783515:A4E84_RS21535
uniprot id: A0A143C353
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

1783515:A4E84 RS24625
gene id: 1783515:A4E84_RS24625
uniprot id: A0A143C4L5
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1783515:A4E84 RS12890
gene id: 1783515:A4E84_RS12890
uniprot id: A0A143BZG0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS28000
gene id: 1783515:A4E84_RS28000
uniprot id: A0A143C6E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS35485
gene id: 1783515:A4E84_RS35485
uniprot id: A0A143CA79
names: Similarity
messages: Belongs to the CdaR family.

1783515:A4E84 RS34790
gene id: 1783515:A4E84_RS34790
uniprot id: A0A143C9V0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1783515:A4E84 RS30905
gene id: 1783515:A4E84_RS30905
uniprot id: A0A143C7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS16465
gene id: 1783515:A4E84_RS16465
uniprot id: A0A143C0S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

1783515:A4E84 RS11135
gene id: 1783515:A4E84_RS11135
uniprot id: A0A143BXS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1783515:A4E84 RS34740
gene id: 1783515:A4E84_RS34740
uniprot id: A0A143C9U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS16545
gene id: 1783515:A4E84_RS16545
uniprot id: A0A143C0F7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1783515:A4E84 RS29490
gene id: 1783515:A4E84_RS29490
uniprot id: A0A143C734
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS37610
gene id: 1783515:A4E84_RS37610
uniprot id: A0A143CC81
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS27975
gene id: 1783515:A4E84_RS27975
uniprot id: A0A143C6E2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1783515:A4E84 RS32470
gene id: 1783515:A4E84_RS32470
uniprot id: A0A143C8R1
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1783515:A4E84 RS37545
gene id: 1783515:A4E84_RS37545
uniprot id: A0A143CB46
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1783515:A4E84 RS30180
gene id: 1783515:A4E84_RS30180
uniprot id: A0A143C7I9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1783515:A4E84 RS03260
gene id: 1783515:A4E84_RS03260
uniprot id: A0A143BTN2
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS18920
gene id: 1783515:A4E84_RS18920
uniprot id: A0A143C1V6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1783515:A4E84 RS28105
gene id: 1783515:A4E84_RS28105
uniprot id: A0A143C7T3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1783515:A4E84 RS01565
gene id: 1783515:A4E84_RS01565
uniprot id: A0A143BT73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1783515:A4E84 RS37280
gene id: 1783515:A4E84_RS37280
uniprot id: A0A143CBL4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS29035
gene id: 1783515:A4E84_RS29035
uniprot id: A0A143C8A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS22565
gene id: 1783515:A4E84_RS22565
uniprot id: A0A143C3K5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1783515:A4E84 RS23310
gene id: 1783515:A4E84_RS23310
uniprot id: A0A143C5C7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS17735
gene id: 1783515:A4E84_RS17735
uniprot id: A0A143C1E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS44900
gene id: 1783515:A4E84_RS44900
uniprot id: A0A143CF76
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS35870
gene id: 1783515:A4E84_RS35870
uniprot id: A0A143CAD0
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

1783515:A4E84 RS28205
gene id: 1783515:A4E84_RS28205
uniprot id: A0A143C6H8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS23765
gene id: 1783515:A4E84_RS23765
uniprot id: A0A143C5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1783515:A4E84 RS12090
gene id: 1783515:A4E84_RS12090
uniprot id: A0A143BYA5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS39385
gene id: 1783515:A4E84_RS39385
uniprot id: A0A143CC24
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1783515:A4E84 RS18775
gene id: 1783515:A4E84_RS18775
uniprot id: A0A143C2Q5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS23995
gene id: 1783515:A4E84_RS23995
uniprot id: A0A143C5P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS09825
gene id: 1783515:A4E84_RS09825
uniprot id: A0A143BX33
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS07955
gene id: 1783515:A4E84_RS07955
uniprot id: A0A143BWC7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1783515:A4E84 RS28530
gene id: 1783515:A4E84_RS28530
uniprot id: A0A143C6N7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1783515:A4E84 RS37850
gene id: 1783515:A4E84_RS37850
uniprot id: A0A143CE57
names: Similarity
messages: Belongs to the peptidase S1 family.

1783515:A4E84 RS28600
gene id: 1783515:A4E84_RS28600
uniprot id: A0A143C6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1783515:A4E84 RS15815
gene id: 1783515:A4E84_RS15815
uniprot id: A0A143C044
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS07265
gene id: 1783515:A4E84_RS07265
uniprot id: A0A143BW10
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS16030
gene id: 1783515:A4E84_RS16030
uniprot id: A0A143C0G0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS08555
gene id: 1783515:A4E84_RS08555
uniprot id: A0A143BWL2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS13010
gene id: 1783515:A4E84_RS13010
uniprot id: A0A143BYW6
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1783515:A4E84 RS06865
gene id: 1783515:A4E84_RS06865
uniprot id: A0A143BVU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1783515:A4E84 RS31580
gene id: 1783515:A4E84_RS31580
uniprot id: A0A143C890
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS06635
gene id: 1783515:A4E84_RS06635
uniprot id: A0A143BWI9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS07425
gene id: 1783515:A4E84_RS07425
uniprot id: A0A143BW32
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1783515:A4E84 RS17750
gene id: 1783515:A4E84_RS17750
uniprot id: A0A143C1A6
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1783515:A4E84 RS15675
gene id: 1783515:A4E84_RS15675
uniprot id: A0A143C0U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS33925
gene id: 1783515:A4E84_RS33925
uniprot id: A0A143C9G7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS33850
gene id: 1783515:A4E84_RS33850
uniprot id: A0A143CAC8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1783515:A4E84 RS07370
gene id: 1783515:A4E84_RS07370
uniprot id: A0A143BW21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1783515:A4E84 RS07140
gene id: 1783515:A4E84_RS07140
uniprot id: A0A143BWT0
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1783515:A4E84 RS16800
gene id: 1783515:A4E84_RS16800
uniprot id: A0A143C0T7
names: Similarity
messages: Belongs to the peptidase S58 family.

1783515:A4E84 RS19530
gene id: 1783515:A4E84_RS19530
uniprot id: A0A143C297
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS39055
gene id: 1783515:A4E84_RS39055
uniprot id: A0A143CBZ5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1783515:A4E84 RS29240
gene id: 1783515:A4E84_RS29240
uniprot id: A0A143CF05
names: Similarity
messages: Belongs to the peptidase S8 family.

1783515:A4E84 RS27430
gene id: 1783515:A4E84_RS27430
uniprot id: A0A143C648
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1783515:A4E84 RS27435
gene id: 1783515:A4E84_RS27435
uniprot id: A0A143C650
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1783515:A4E84 RS24545
gene id: 1783515:A4E84_RS24545
uniprot id: A0A143C4H5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1783515:A4E84 RS23955
gene id: 1783515:A4E84_RS23955
uniprot id: A0A143C465
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS07135
gene id: 1783515:A4E84_RS07135
uniprot id: A0A143BVL4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS33890
gene id: 1783515:A4E84_RS33890
uniprot id: A0A143C9D6
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1783515:A4E84 RS12550
gene id: 1783515:A4E84_RS12550
uniprot id: A0A143BZ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

1783515:A4E84 RS29585
gene id: 1783515:A4E84_RS29585
uniprot id: A0A143C776
names: Similarity
messages: Belongs to the RelA/SpoT family.

1783515:A4E84 RS22560
gene id: 1783515:A4E84_RS22560
uniprot id: A0A143C3R0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1783515:A4E84 RS07395
gene id: 1783515:A4E84_RS07395
uniprot id: A0A143BVR6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1783515:A4E84 RS02110
gene id: 1783515:A4E84_RS02110
uniprot id: A0A143CDQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1783515:A4E84 RS13490
gene id: 1783515:A4E84_RS13490
uniprot id: A0A143BZ00
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1783515:A4E84 RS24380
gene id: 1783515:A4E84_RS24380
uniprot id: A0A143C5B0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1783515:A4E84 RS08600
gene id: 1783515:A4E84_RS08600
uniprot id: A0A143BXH5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS17625
gene id: 1783515:A4E84_RS17625
uniprot id: A0A143C1C6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS31890
gene id: 1783515:A4E84_RS31890
uniprot id: A0A143C8G7
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1783515:A4E84 RS09635
gene id: 1783515:A4E84_RS09635
uniprot id: A0A143BY05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS09505
gene id: 1783515:A4E84_RS09505
uniprot id: A0A143BY21
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS24300
gene id: 1783515:A4E84_RS24300
uniprot id: A0A143C5T6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1783515:A4E84 RS24750
gene id: 1783515:A4E84_RS24750
uniprot id: A0A143C4J9
names: Similarity
messages: Belongs to the peptidase C40 family.

1783515:A4E84 RS12140
gene id: 1783515:A4E84_RS12140
uniprot id: A0A143BYA9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1783515:A4E84 RS12755
gene id: 1783515:A4E84_RS12755
uniprot id: A0A143BYL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

1783515:A4E84 RS33265
gene id: 1783515:A4E84_RS33265
uniprot id: A0A143CA21
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1783515:A4E84 RS24520
gene id: 1783515:A4E84_RS24520
uniprot id: A0A143C4J7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1783515:A4E84 RS24135
gene id: 1783515:A4E84_RS24135
uniprot id: A0A143C5R1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1783515:A4E84 RS19860
gene id: 1783515:A4E84_RS19860
uniprot id: A0A143C378
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1783515:A4E84 RS00970
gene id: 1783515:A4E84_RS00970
uniprot id: A0A143BSY0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS30290
gene id: 1783515:A4E84_RS30290
uniprot id: A0A143C7I2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1783515:A4E84 RS23260
gene id: 1783515:A4E84_RS23260
uniprot id: A0A143C5B8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS02885
gene id: 1783515:A4E84_RS02885
uniprot id: A0A143BUI9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1783515:A4E84 RS18320
gene id: 1783515:A4E84_RS18320
uniprot id: A0A143C1C3
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1783515:A4E84 RS09310
gene id: 1783515:A4E84_RS09310
uniprot id: A0A143BWQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1783515:A4E84 RS07300
gene id: 1783515:A4E84_RS07300
uniprot id: A0A143BVP1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1783515:A4E84 RS09370
gene id: 1783515:A4E84_RS09370
uniprot id: A0A143BXV9
names: Similarity
messages: Belongs to the CobH/CbiC family.

1783515:A4E84 RS35800
gene id: 1783515:A4E84_RS35800
uniprot id: A0A143CAY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

1783515:A4E84 RS31795
gene id: 1783515:A4E84_RS31795
uniprot id: A0A143C8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1783515:A4E84 RS37140
gene id: 1783515:A4E84_RS37140
uniprot id: A0A143CAY2
names: Similarity
messages: Belongs to the amidinotransferase family.

1783515:A4E84 RS27495
gene id: 1783515:A4E84_RS27495
uniprot id: A0A143C7G6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1783515:A4E84 RS27120
gene id: 1783515:A4E84_RS27120
uniprot id: A0A143C601
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1783515:A4E84 RS32050
gene id: 1783515:A4E84_RS32050
uniprot id: A0A143C8I5
names: Similarity
messages: Belongs to the TPP enzyme family.

1783515:A4E84 RS28705
gene id: 1783515:A4E84_RS28705
uniprot id: A0A143C6Q5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1783515:A4E84 RS07105
gene id: 1783515:A4E84_RS07105
uniprot id: A0A143BVX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1783515:A4E84 RS24155
gene id: 1783515:A4E84_RS24155
uniprot id: A0A143C5A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1783515:A4E84 RS15270
gene id: 1783515:A4E84_RS15270
uniprot id: A0A143BZT9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1783515:A4E84 RS24975
gene id: 1783515:A4E84_RS24975
uniprot id: A0A143C4Q1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS02995
gene id: 1783515:A4E84_RS02995
uniprot id: A0A143BTJ4
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS20055
gene id: 1783515:A4E84_RS20055
uniprot id: A0A143C2E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1783515:A4E84 RS37175
gene id: 1783515:A4E84_RS37175
uniprot id: A0A143CAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS10845
gene id: 1783515:A4E84_RS10845
uniprot id: A0A143BXW1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS13520
gene id: 1783515:A4E84_RS13520
uniprot id: A0A143BZ48
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1783515:A4E84 RS28025
gene id: 1783515:A4E84_RS28025
uniprot id: A0A143C6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1783515:A4E84 RS11730
gene id: 1783515:A4E84_RS11730
uniprot id: A0A143BY37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1783515:A4E84 RS22300
gene id: 1783515:A4E84_RS22300
uniprot id: A0A143C3B1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1783515:A4E84 RS14115
gene id: 1783515:A4E84_RS14115
uniprot id: A0A143BZH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1783515:A4E84 RS28730
gene id: 1783515:A4E84_RS28730
uniprot id: A0A143C6S3
names: Similarity
messages: Belongs to the DprA/Smf family.

1783515:A4E84 RS03610
gene id: 1783515:A4E84_RS03610
uniprot id: A0A143BV28
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1783515:A4E84 RS36885
gene id: 1783515:A4E84_RS36885
uniprot id: A0A143CAU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1783515:A4E84 RS39260
gene id: 1783515:A4E84_RS39260
uniprot id: A0A143CC25
names: Similarity
messages: Belongs to the peptidase S1 family.

1783515:A4E84 RS23020
gene id: 1783515:A4E84_RS23020
uniprot id: A0A143C3T5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS36850
gene id: 1783515:A4E84_RS36850
uniprot id: A0A143CAT0
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

1783515:A4E84 RS17955
gene id: 1783515:A4E84_RS17955
uniprot id: A0A143C219
names: Similarity
messages: Belongs to the CutC family.

1783515:A4E84 RS02065
gene id: 1783515:A4E84_RS02065
uniprot id: A0A143BT31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS09770
gene id: 1783515:A4E84_RS09770
uniprot id: A0A143BY70
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1783515:A4E84 RS07375
gene id: 1783515:A4E84_RS07375
uniprot id: A0A143BW05
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1783515:A4E84 RS23970
gene id: 1783515:A4E84_RS23970
uniprot id: A0A143C541
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS35835
gene id: 1783515:A4E84_RS35835
uniprot id: A0A143CAD4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1783515:A4E84 RS16595
gene id: 1783515:A4E84_RS16595
uniprot id: A0A143C0G7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS27365
gene id: 1783515:A4E84_RS27365
uniprot id: A0A143C6S9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1783515:A4E84 RS04220
gene id: 1783515:A4E84_RS04220
uniprot id: A0A143BUG4
names: Subcellular Location Annotation
messages: Nucleus

1783515:A4E84 RS22665
gene id: 1783515:A4E84_RS22665
uniprot id: A0A143C3W5
names: Similarity
messages: Belongs to the peptidase S13 family.

1783515:A4E84 RS10360
gene id: 1783515:A4E84_RS10360
uniprot id: A0A143BYI2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS08790
gene id: 1783515:A4E84_RS08790
uniprot id: A0A143BWS3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS08530
gene id: 1783515:A4E84_RS08530
uniprot id: A0A143BWB1
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1783515:A4E84 RS28635
gene id: 1783515:A4E84_RS28635
uniprot id: A0A143C6R4
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1783515:A4E84 RS03625
gene id: 1783515:A4E84_RS03625
uniprot id: A0A143BTU3
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

1783515:A4E84 RS12945
gene id: 1783515:A4E84_RS12945
uniprot id: A0A143BZG8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1783515:A4E84 RS32435
gene id: 1783515:A4E84_RS32435
uniprot id: A0A143C9Y0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1783515:A4E84 RS25200
gene id: 1783515:A4E84_RS25200
uniprot id: A0A143C5S8
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1783515:A4E84 RS36110
gene id: 1783515:A4E84_RS36110
uniprot id: A0A143CAI0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1783515:A4E84 RS28570
gene id: 1783515:A4E84_RS28570
uniprot id: A0A143C7G3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1783515:A4E84 RS02970
gene id: 1783515:A4E84_RS02970
uniprot id: A0A143BTV6
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1783515:A4E84 RS16960
gene id: 1783515:A4E84_RS16960
uniprot id: A0A143CD36
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1783515:A4E84 RS38980
gene id: 1783515:A4E84_RS38980
uniprot id: A0A143CBX6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1783515:A4E84 RS37770
gene id: 1783515:A4E84_RS37770
uniprot id: A0A143CBT5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1783515:A4E84 RS07430
gene id: 1783515:A4E84_RS07430
uniprot id: A0A143BW13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS33725
gene id: 1783515:A4E84_RS33725
uniprot id: A0A143C9X5
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Belongs to the complex I 51 kDa subunit family.

1783515:A4E84 RS31355
gene id: 1783515:A4E84_RS31355
uniprot id: A0A143C908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

1783515:A4E84 RS30635
gene id: 1783515:A4E84_RS30635
uniprot id: A0A143C7T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS13940
gene id: 1783515:A4E84_RS13940
uniprot id: A0A143C0E2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS17330
gene id: 1783515:A4E84_RS17330
uniprot id: A0A143C201
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1783515:A4E84 RS15600
gene id: 1783515:A4E84_RS15600
uniprot id: A0A143BZZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1783515:A4E84 RS34050
gene id: 1783515:A4E84_RS34050
uniprot id: A0A143CAW0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS07475
gene id: 1783515:A4E84_RS07475
uniprot id: A0A143BW41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1783515:A4E84 RS26410
gene id: 1783515:A4E84_RS26410
uniprot id: A0A143C5H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1783515:A4E84 RS27700
gene id: 1783515:A4E84_RS27700
uniprot id: A0A143C667
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS33455
gene id: 1783515:A4E84_RS33455
uniprot id: A0A143CET0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

1783515:A4E84 RS31910
gene id: 1783515:A4E84_RS31910
uniprot id: A0A143C8E0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1783515:A4E84 RS03650
gene id: 1783515:A4E84_RS03650
uniprot id: A0A143BU66
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1783515:A4E84 RS34135
gene id: 1783515:A4E84_RS34135
uniprot id: A0A143C9J3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS12245
gene id: 1783515:A4E84_RS12245
uniprot id: A0A143BYI1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS05445
gene id: 1783515:A4E84_RS05445
uniprot id: A0A143BUU3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1783515:A4E84 RS02270
gene id: 1783515:A4E84_RS02270
uniprot id: A0A143CCZ0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1783515:A4E84 RS07350
gene id: 1783515:A4E84_RS07350
uniprot id: A0A143BVQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1783515:A4E84 RS38220
gene id: 1783515:A4E84_RS38220
uniprot id: A0A143CBI1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1783515:A4E84 RS34715
gene id: 1783515:A4E84_RS34715
uniprot id: A0A143C9T0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1783515:A4E84 RS37755
gene id: 1783515:A4E84_RS37755
uniprot id: A0A143CB99
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

1783515:A4E84 RS37495
gene id: 1783515:A4E84_RS37495
uniprot id: A0A143CBQ2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1783515:A4E84 RS26675
gene id: 1783515:A4E84_RS26675
uniprot id: A0A143C718
names: Similarity
messages: Belongs to the peptidase S16 family.

1783515:A4E84 RS34425
gene id: 1783515:A4E84_RS34425
uniprot id: A0A143C9N7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS30760
gene id: 1783515:A4E84_RS30760
uniprot id: A0A143C7W8
names: Similarity
messages: Belongs to the MmpS family.

1783515:A4E84 RS05225
gene id: 1783515:A4E84_RS05225
uniprot id: A0A143BUR1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS19145
gene id: 1783515:A4E84_RS19145
uniprot id: A0A143C2W5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1783515:A4E84 RS34880
gene id: 1783515:A4E84_RS34880
uniprot id: A0A143CAH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1783515:A4E84 RS16085
gene id: 1783515:A4E84_RS16085
uniprot id: A0A143C0I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1783515:A4E84 RS21135
gene id: 1783515:A4E84_RS21135
uniprot id: A0A143C341
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1783515:A4E84 RS15515
gene id: 1783515:A4E84_RS15515
uniprot id: A0A143C039
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1783515:A4E84 RS08315
gene id: 1783515:A4E84_RS08315
uniprot id: A0A143BX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1783515:A4E84 RS08525
gene id: 1783515:A4E84_RS08525
uniprot id: A0A143CCS1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS00910
gene id: 1783515:A4E84_RS00910
uniprot id: A0A143BSV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS23650
gene id: 1783515:A4E84_RS23650
uniprot id: A0A143C3Z7
names: Similarity
messages: Belongs to the peptidase A24 family.

1783515:A4E84 RS14210
gene id: 1783515:A4E84_RS14210
uniprot id: A0A143BZD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1783515:A4E84 RS23180
gene id: 1783515:A4E84_RS23180
uniprot id: A0A143C410
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS16425
gene id: 1783515:A4E84_RS16425
uniprot id: A0A143C0P1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1783515:A4E84 RS28475
gene id: 1783515:A4E84_RS28475
uniprot id: A0A143C6S8
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

1783515:A4E84 RS31340
gene id: 1783515:A4E84_RS31340
uniprot id: A0A143C851
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS19205
gene id: 1783515:A4E84_RS19205
uniprot id: A0A143C1Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS15905
gene id: 1783515:A4E84_RS15905
uniprot id: A0A143C0H3
names: Similarity
messages: Belongs to the PGI/PMI family.

1783515:A4E84 RS04675
gene id: 1783515:A4E84_RS04675
uniprot id: A0A143BUN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS10575
gene id: 1783515:A4E84_RS10575
uniprot id: A0A143BXN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1783515:A4E84 RS32145
gene id: 1783515:A4E84_RS32145
uniprot id: A0A143C8I9
names: Similarity
messages: Belongs to the peptidase C40 family.

1783515:A4E84 RS12225
gene id: 1783515:A4E84_RS12225
uniprot id: A0A143BZ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1783515:A4E84 RS02120
gene id: 1783515:A4E84_RS02120
uniprot id: A0A143BT79
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

1783515:A4E84 RS34645
gene id: 1783515:A4E84_RS34645
uniprot id: A0A143C9T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1783515:A4E84 RS27980
gene id: 1783515:A4E84_RS27980
uniprot id: A0A143C6D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1783515:A4E84 RS08440
gene id: 1783515:A4E84_RS08440
uniprot id: A0A143BWL3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24935
gene id: 1783515:A4E84_RS24935
uniprot id: A0A143C5N5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1783515:A4E84 RS17440
gene id: 1783515:A4E84_RS17440
uniprot id: A0A143C223
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1783515:A4E84 RS05840
gene id: 1783515:A4E84_RS05840
uniprot id: A0A143BV79
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1783515:A4E84 RS33845
gene id: 1783515:A4E84_RS33845
uniprot id: A0A143CA02
names: Similarity
messages: Belongs to the TPP enzyme family.

1783515:A4E84 RS23090
gene id: 1783515:A4E84_RS23090
uniprot id: A0A143C3P2
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1783515:A4E84 RS24170
gene id: 1783515:A4E84_RS24170
uniprot id: A0A143C4H2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1783515:A4E84 RS19175
gene id: 1783515:A4E84_RS19175
uniprot id: A0A143C329
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1783515:A4E84 RS27870
gene id: 1783515:A4E84_RS27870
uniprot id: A0A143C699
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1783515:A4E84 RS27205
gene id: 1783515:A4E84_RS27205
uniprot id: A0A143CDJ4
names: Similarity
messages: Belongs to the asp23 family.

1783515:A4E84 RS15385
gene id: 1783515:A4E84_RS15385
uniprot id: A0A143C000
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1783515:A4E84 RS34795
gene id: 1783515:A4E84_RS34795
uniprot id: A0A143C9T8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS01760
gene id: 1783515:A4E84_RS01760
uniprot id: A0A143BSY9
names: Subcellular Location Annotation
messages: Cell membrane

1783515:A4E84 RS24450
gene id: 1783515:A4E84_RS24450
uniprot id: A0A143C4J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS14680
gene id: 1783515:A4E84_RS14680
uniprot id: A0A143BZP2
names: Similarity
messages: Belongs to the IucA/IucC family.

1783515:A4E84 RS07380
gene id: 1783515:A4E84_RS07380
uniprot id: A0A143BW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1783515:A4E84 RS08050
gene id: 1783515:A4E84_RS08050
uniprot id: A0A143BX30
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS14705
gene id: 1783515:A4E84_RS14705
uniprot id: A0A143BZJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1783515:A4E84 RS18215
gene id: 1783515:A4E84_RS18215
uniprot id: A0A143C1F4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1783515:A4E84 RS31865
gene id: 1783515:A4E84_RS31865
uniprot id: A0A143C8D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS07205
gene id: 1783515:A4E84_RS07205
uniprot id: A0A143BWT3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS11140
gene id: 1783515:A4E84_RS11140
uniprot id: A0A143BXS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1783515:A4E84 RS39335
gene id: 1783515:A4E84_RS39335
uniprot id: A0A143CC16
names: Similarity
messages: Belongs to the GcvT family.

1783515:A4E84 RS21980
gene id: 1783515:A4E84_RS21980
uniprot id: A0A143C370
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS29935
gene id: 1783515:A4E84_RS29935
uniprot id: A0A143C7I0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1783515:A4E84 RS17315
gene id: 1783515:A4E84_RS17315
uniprot id: A0A143C0T1
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

1783515:A4E84 RS00360
gene id: 1783515:A4E84_RS00360
uniprot id: A0A143CCA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1783515:A4E84 RS26865
gene id: 1783515:A4E84_RS26865
uniprot id: A0A143C6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS14620
gene id: 1783515:A4E84_RS14620
uniprot id: A0A143C095
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1783515:A4E84 RS33395
gene id: 1783515:A4E84_RS33395
uniprot id: A0A143C936
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1783515:A4E84 RS13265
gene id: 1783515:A4E84_RS13265
uniprot id: A0A143CDG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1783515:A4E84 RS37145
gene id: 1783515:A4E84_RS37145
uniprot id: A0A143CCA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1783515:A4E84 RS28970
gene id: 1783515:A4E84_RS28970
uniprot id: A0A143C6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS16275
gene id: 1783515:A4E84_RS16275
uniprot id: A0A143C0D6
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1783515:A4E84 RS14235
gene id: 1783515:A4E84_RS14235
uniprot id: A0A143BZI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1783515:A4E84 RS25430
gene id: 1783515:A4E84_RS25430
uniprot id: A0A143C534
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1783515:A4E84 RS11280
gene id: 1783515:A4E84_RS11280
uniprot id: A0A143BZ19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1783515:A4E84 RS13555
gene id: 1783515:A4E84_RS13555
uniprot id: A0A143C025
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1783515:A4E84 RS29980
gene id: 1783515:A4E84_RS29980
uniprot id: A0A143C8R5
names: Subcellular Location Annotation
messages: Cytoplasm

1783515:A4E84 RS34600
gene id: 1783515:A4E84_RS34600
uniprot id: A0A143CB56
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1783515:A4E84 RS35860
gene id: 1783515:A4E84_RS35860
uniprot id: A0A143CAC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

1783515:A4E84 RS38700
gene id: 1783515:A4E84_RS38700
uniprot id: A0A143CBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS35405
gene id: 1783515:A4E84_RS35405
uniprot id: A0A143CDX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1783515:A4E84 RS27625
gene id: 1783515:A4E84_RS27625
uniprot id: A0A143C6Z1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS26610
gene id: 1783515:A4E84_RS26610
uniprot id: A0A143C5N7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1783515:A4E84 RS22635
gene id: 1783515:A4E84_RS22635
uniprot id: A0A143C508
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS18225
gene id: 1783515:A4E84_RS18225
uniprot id: A0A143C273
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1783515:A4E84 RS06755
gene id: 1783515:A4E84_RS06755
uniprot id: A0A143BVR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1783515:A4E84 RS28450
gene id: 1783515:A4E84_RS28450
uniprot id: A0A143C6F4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1783515:A4E84 RS07065
gene id: 1783515:A4E84_RS07065
uniprot id: A0A143BVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

1783515:A4E84 RS17820
gene id: 1783515:A4E84_RS17820
uniprot id: A0A143C127
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1783515:A4E84 RS24205
gene id: 1783515:A4E84_RS24205
uniprot id: A0A143C5B1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS08880
gene id: 1783515:A4E84_RS08880
uniprot id: A0A143BWV3
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1783515:A4E84 RS16600
gene id: 1783515:A4E84_RS16600
uniprot id: A0A143C0I7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS13215
gene id: 1783515:A4E84_RS13215
uniprot id: A0A143BZL8
names: Similarity
messages: Belongs to the DapA family.

1783515:A4E84 RS34745
gene id: 1783515:A4E84_RS34745
uniprot id: A0A143C9S8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS18780
gene id: 1783515:A4E84_RS18780
uniprot id: A0A143C2H1
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

1783515:A4E84 RS18540
gene id: 1783515:A4E84_RS18540
uniprot id: A0A143CD65
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1783515:A4E84 RS05980
gene id: 1783515:A4E84_RS05980
uniprot id: A0A143BV12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1783515:A4E84 RS13530
gene id: 1783515:A4E84_RS13530
uniprot id: A0A143BZ82
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS30925
gene id: 1783515:A4E84_RS30925
uniprot id: A0A143C7W0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS18680
gene id: 1783515:A4E84_RS18680
uniprot id: A0A143C1R1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1783515:A4E84 RS02930
gene id: 1783515:A4E84_RS02930
uniprot id: A0A143BTM0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS26470
gene id: 1783515:A4E84_RS26470
uniprot id: A0A143C5F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS39250
gene id: 1783515:A4E84_RS39250
uniprot id: A0A143CC00
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1783515:A4E84 RS26040
gene id: 1783515:A4E84_RS26040
uniprot id: A0A143C662
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1783515:A4E84 RS03785
gene id: 1783515:A4E84_RS03785
uniprot id: A0A143BTX2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS15490
gene id: 1783515:A4E84_RS15490
uniprot id: A0A143C017
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS35345
gene id: 1783515:A4E84_RS35345
uniprot id: A0A143CA92
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1783515:A4E84 RS11795
gene id: 1783515:A4E84_RS11795
uniprot id: A0A143BY47
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS11015
gene id: 1783515:A4E84_RS11015
uniprot id: A0A143BYX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1783515:A4E84 RS23745
gene id: 1783515:A4E84_RS23745
uniprot id: A0A143C4E1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS36575
gene id: 1783515:A4E84_RS36575
uniprot id: A0A143CAP3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS10030
gene id: 1783515:A4E84_RS10030
uniprot id: A0A143BX73
names: Similarity
messages: Belongs to the peptidase S66 family.

1783515:A4E84 RS30805
gene id: 1783515:A4E84_RS30805
uniprot id: A0A143C8H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS28695
gene id: 1783515:A4E84_RS28695
uniprot id: A0A143C856
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1783515:A4E84 RS06040
gene id: 1783515:A4E84_RS06040
uniprot id: A0A143BW82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1783515:A4E84 RS20520
gene id: 1783515:A4E84_RS20520
uniprot id: A0A143C2F8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1783515:A4E84 RS24180
gene id: 1783515:A4E84_RS24180
uniprot id: A0A143C4G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1783515:A4E84 RS09675
gene id: 1783515:A4E84_RS09675
uniprot id: A0A143BX02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

1783515:A4E84 RS06005
gene id: 1783515:A4E84_RS06005
uniprot id: A0A143BVD5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS13695
gene id: 1783515:A4E84_RS13695
uniprot id: A0A143BZ94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1783515:A4E84 RS10535
gene id: 1783515:A4E84_RS10535
uniprot id: A0A143BXG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1783515:A4E84 RS29390
gene id: 1783515:A4E84_RS29390
uniprot id: A0A143C702
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1783515:A4E84 RS30880
gene id: 1783515:A4E84_RS30880
uniprot id: A0A143C7V5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1783515:A4E84 RS31075
gene id: 1783515:A4E84_RS31075
uniprot id: A0A143C8M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1783515:A4E84 RS32280
gene id: 1783515:A4E84_RS32280
uniprot id: A0A143C8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1783515:A4E84 RS24355
gene id: 1783515:A4E84_RS24355
uniprot id: A0A143C5U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1783515:A4E84 RS32800
gene id: 1783515:A4E84_RS32800
uniprot id: A0A143C8V1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS16280
gene id: 1783515:A4E84_RS16280
uniprot id: A0A143C0H6
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1783515:A4E84 RS08960
gene id: 1783515:A4E84_RS08960
uniprot id: A0A143BWL6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1783515:A4E84 RS19595
gene id: 1783515:A4E84_RS19595
uniprot id: A0A143C266
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1783515:A4E84 RS35520
gene id: 1783515:A4E84_RS35520
uniprot id: A0A143CB90
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24955
gene id: 1783515:A4E84_RS24955
uniprot id: A0A143C4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS38735
gene id: 1783515:A4E84_RS38735
uniprot id: A0A143CCR6
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1783515:A4E84 RS13145
gene id: 1783515:A4E84_RS13145
uniprot id: A0A143BYT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS31820
gene id: 1783515:A4E84_RS31820
uniprot id: A0A143C8E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1783515:A4E84 RS07115
gene id: 1783515:A4E84_RS07115
uniprot id: A0A143BVV1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1783515:A4E84 RS24270
gene id: 1783515:A4E84_RS24270
uniprot id: A0A143C5B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1783515:A4E84 RS15745
gene id: 1783515:A4E84_RS15745
uniprot id: A0A143C0B2
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1783515:A4E84 RS11665
gene id: 1783515:A4E84_RS11665
uniprot id: A0A143BZ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS04765
gene id: 1783515:A4E84_RS04765
uniprot id: A0A143BUD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EfeM/EfeO family.
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1783515:A4E84 RS18980
gene id: 1783515:A4E84_RS18980
uniprot id: A0A143C1V7
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1783515:A4E84 RS37440
gene id: 1783515:A4E84_RS37440
uniprot id: A0A143CB78
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS30955
gene id: 1783515:A4E84_RS30955
uniprot id: A0A143C7Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1783515:A4E84 RS13245
gene id: 1783515:A4E84_RS13245
uniprot id: A0A143BYT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1783515:A4E84 RS11170
gene id: 1783515:A4E84_RS11170
uniprot id: A0A143BXY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1783515:A4E84 RS17055
gene id: 1783515:A4E84_RS17055
uniprot id: A0A143C0X5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS05430
gene id: 1783515:A4E84_RS05430
uniprot id: A0A143BV08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1783515:A4E84 RS01795
gene id: 1783515:A4E84_RS01795
uniprot id: A0A143BTA8
names: Similarity
messages: Belongs to the peptidase S1 family.

1783515:A4E84 RS13950
gene id: 1783515:A4E84_RS13950
uniprot id: A0A143BZ73
names: Similarity
messages: Belongs to the peptidase M1 family.

1783515:A4E84 RS38790
gene id: 1783515:A4E84_RS38790
uniprot id: A0A143CCU1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS10400
gene id: 1783515:A4E84_RS10400
uniprot id: A0A143BXK1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1783515:A4E84 RS26720
gene id: 1783515:A4E84_RS26720
uniprot id: A0A143C5R0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1783515:A4E84 RS14930
gene id: 1783515:A4E84_RS14930
uniprot id: A0A143BZR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS37910
gene id: 1783515:A4E84_RS37910
uniprot id: A0A143CBC8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1783515:A4E84 RS13810
gene id: 1783515:A4E84_RS13810
uniprot id: A0A143BZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1783515:A4E84 RS01050
gene id: 1783515:A4E84_RS01050
uniprot id: A0A143BSQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1783515:A4E84 RS32605
gene id: 1783515:A4E84_RS32605
uniprot id: A0A143C8S3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS06990
gene id: 1783515:A4E84_RS06990
uniprot id: A0A143BVT7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS03175
gene id: 1783515:A4E84_RS03175
uniprot id: A0A143BU01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

1783515:A4E84 RS01420
gene id: 1783515:A4E84_RS01420
uniprot id: A0A143BT50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1783515:A4E84 RS12390
gene id: 1783515:A4E84_RS12390
uniprot id: A0A143BZ71
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS09615
gene id: 1783515:A4E84_RS09615
uniprot id: A0A143BY39
names: Similarity
messages: Belongs to the DapA family.

1783515:A4E84 RS15325
gene id: 1783515:A4E84_RS15325
uniprot id: A0A143BZU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1783515:A4E84 RS24455
gene id: 1783515:A4E84_RS24455
uniprot id: A0A143C4K7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS24295
gene id: 1783515:A4E84_RS24295
uniprot id: A0A143C4H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1783515:A4E84 RS18930
gene id: 1783515:A4E84_RS18930
uniprot id: A0A143C1W4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS12610
gene id: 1783515:A4E84_RS12610
uniprot id: A0A143BYU8
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1783515:A4E84 RS13300
gene id: 1783515:A4E84_RS13300
uniprot id: A0A143C029
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1783515:A4E84 RS17175
gene id: 1783515:A4E84_RS17175
uniprot id: A0A143C104
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS03780
gene id: 1783515:A4E84_RS03780
uniprot id: A0A143BTX4
names: Similarity
messages: Belongs to the CdaR family.

1783515:A4E84 RS35650
gene id: 1783515:A4E84_RS35650
uniprot id: A0A143CA97
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1783515:A4E84 RS10605
gene id: 1783515:A4E84_RS10605
uniprot id: A0A143BYL0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS15395
gene id: 1783515:A4E84_RS15395
uniprot id: A0A143C0N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS01295
gene id: 1783515:A4E84_RS01295
uniprot id: A0A143BTZ1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS26370
gene id: 1783515:A4E84_RS26370
uniprot id: A0A143C5H8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1783515:A4E84 RS23880
gene id: 1783515:A4E84_RS23880
uniprot id: A0A143C4B6
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

1783515:A4E84 RS18805
gene id: 1783515:A4E84_RS18805
uniprot id: A0A143CEK2
names: Similarity
messages: Belongs to the peptidase C40 family.

1783515:A4E84 RS10920
gene id: 1783515:A4E84_RS10920
uniprot id: A0A143BXL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1783515:A4E84 RS03690
gene id: 1783515:A4E84_RS03690
uniprot id: A0A143BV19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1783515:A4E84 RS24055
gene id: 1783515:A4E84_RS24055
uniprot id: A0A143C4C3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1783515:A4E84 RS05885
gene id: 1783515:A4E84_RS05885
uniprot id: A0A143BVW6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS15955
gene id: 1783515:A4E84_RS15955
uniprot id: A0A143C0Z8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monovalent cation. The ion could be potassium.

1783515:A4E84 RS34865
gene id: 1783515:A4E84_RS34865
uniprot id: A0A143C9W7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1783515:A4E84 RS07320
gene id: 1783515:A4E84_RS07320
uniprot id: A0A143BW12
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS13420
gene id: 1783515:A4E84_RS13420
uniprot id: A0A143BYY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1783515:A4E84 RS21635
gene id: 1783515:A4E84_RS21635
uniprot id: A0A143C392
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1783515:A4E84 RS28285
gene id: 1783515:A4E84_RS28285
uniprot id: A0A143C797
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1783515:A4E84 RS32740
gene id: 1783515:A4E84_RS32740
uniprot id: A0A143C8U9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1783515:A4E84 RS13935
gene id: 1783515:A4E84_RS13935
uniprot id: A0A143CE17
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS03550
gene id: 1783515:A4E84_RS03550
uniprot id: A0A143BU58
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS24360
gene id: 1783515:A4E84_RS24360
uniprot id: A0A143C4B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1783515:A4E84 RS03000
gene id: 1783515:A4E84_RS03000
uniprot id: A0A143BUS2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1783515:A4E84 RS20650
gene id: 1783515:A4E84_RS20650
uniprot id: A0A143C3D9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS26145
gene id: 1783515:A4E84_RS26145
uniprot id: A0A143C6R3
names: Similarity
messages: Belongs to the peptidase S8 family.

1783515:A4E84 RS17865
gene id: 1783515:A4E84_RS17865
uniprot id: A0A143C2E9
names: Subcellular Location Annotation
messages: Cell membrane

1783515:A4E84 RS10255
gene id: 1783515:A4E84_RS10255
uniprot id: A0A143BXB1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS09265
gene id: 1783515:A4E84_RS09265
uniprot id: A0A143BXT8
names: Similarity
messages: Belongs to the asp23 family.

1783515:A4E84 RS39320
gene id: 1783515:A4E84_RS39320
uniprot id: A0A143CC34
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS19940
gene id: 1783515:A4E84_RS19940
uniprot id: A0A143C2C0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS36020
gene id: 1783515:A4E84_RS36020
uniprot id: A0A143CFA1
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1783515:A4E84 RS06845
gene id: 1783515:A4E84_RS06845
uniprot id: A0A143BVF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1783515:A4E84 RS06715
gene id: 1783515:A4E84_RS06715
uniprot id: A0A143BWN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS34520
gene id: 1783515:A4E84_RS34520
uniprot id: A0A143CAB5
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1783515:A4E84 RS30000
gene id: 1783515:A4E84_RS30000
uniprot id: A0A143C823
names: Similarity
messages: Belongs to the citrate synthase family.

1783515:A4E84 RS22410
gene id: 1783515:A4E84_RS22410
uniprot id: A0A143C3D0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS17050
gene id: 1783515:A4E84_RS17050
uniprot id: A0A143C124
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS36915
gene id: 1783515:A4E84_RS36915
uniprot id: A0A143CAU0
names: Similarity
messages: Belongs to the TPP enzyme family.

1783515:A4E84 RS29065
gene id: 1783515:A4E84_RS29065
uniprot id: A0A143C726
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1783515:A4E84 RS20075
gene id: 1783515:A4E84_RS20075
uniprot id: A0A143C2E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1783515:A4E84 RS04775
gene id: 1783515:A4E84_RS04775
uniprot id: A0A143BVJ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1783515:A4E84 RS27780
gene id: 1783515:A4E84_RS27780
uniprot id: A0A143C6A2
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1783515:A4E84 RS28755
gene id: 1783515:A4E84_RS28755
uniprot id: A0A143C6R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1783515:A4E84 RS14605
gene id: 1783515:A4E84_RS14605
uniprot id: A0A143BZH3
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1783515:A4E84 RS38010
gene id: 1783515:A4E84_RS38010
uniprot id: A0A143CBW3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS32365
gene id: 1783515:A4E84_RS32365
uniprot id: A0A143C8N7
names: Similarity
messages: Belongs to the malate synthase family.

1783515:A4E84 RS05835
gene id: 1783515:A4E84_RS05835
uniprot id: A0A143BVA5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS04615
gene id: 1783515:A4E84_RS04615
uniprot id: A0A143BUM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

1783515:A4E84 RS07240
gene id: 1783515:A4E84_RS07240
uniprot id: A0A143BVR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1783515:A4E84 RS06540
gene id: 1783515:A4E84_RS06540
uniprot id: A0A143BVN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1783515:A4E84 RS13710
gene id: 1783515:A4E84_RS13710
uniprot id: A0A143BZ07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1783515:A4E84 RS02095
gene id: 1783515:A4E84_RS02095
uniprot id: A0A143BTF6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1783515:A4E84 RS21415
gene id: 1783515:A4E84_RS21415
uniprot id: A0A143C359
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS45375
gene id: 1783515:A4E84_RS45375
uniprot id: A0A143BV97
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1783515:A4E84 RS13665
gene id: 1783515:A4E84_RS13665
uniprot id: A0A143BZ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1783515:A4E84 RS12705
gene id: 1783515:A4E84_RS12705
uniprot id: A0A143BYJ5
names: Similarity
messages: Belongs to the UPF0434 family.

1783515:A4E84 RS37390
gene id: 1783515:A4E84_RS37390
uniprot id: A0A143CE45
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS17425
gene id: 1783515:A4E84_RS17425
uniprot id: A0A143C0V5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1783515:A4E84 RS06405
gene id: 1783515:A4E84_RS06405
uniprot id: A0A143BV83
names: Similarity
messages: Belongs to the XFP family.

1783515:A4E84 RS17040
gene id: 1783515:A4E84_RS17040
uniprot id: A0A143C1K0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS34060
gene id: 1783515:A4E84_RS34060
uniprot id: A0A143C9H4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS22445
gene id: 1783515:A4E84_RS22445
uniprot id: A0A143C3P0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1783515:A4E84 RS22530
gene id: 1783515:A4E84_RS22530
uniprot id: A0A143C3H2
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1783515:A4E84 RS04415
gene id: 1783515:A4E84_RS04415
uniprot id: A0A143BVD7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1783515:A4E84 RS01680
gene id: 1783515:A4E84_RS01680
uniprot id: A0A143BT94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
messages: Belongs to the glycosyl hydrolase 46 family.
messages: Secreted

1783515:A4E84 RS21995
gene id: 1783515:A4E84_RS21995
uniprot id: A0A143C395
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1783515:A4E84 RS15280
gene id: 1783515:A4E84_RS15280
uniprot id: A0A143BZX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1783515:A4E84 RS24290
gene id: 1783515:A4E84_RS24290
uniprot id: A0A143C4G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1783515:A4E84 RS05740
gene id: 1783515:A4E84_RS05740
uniprot id: A0A143BUV5
names: Similarity
messages: Belongs to the FPG family.

1783515:A4E84 RS27375
gene id: 1783515:A4E84_RS27375
uniprot id: A0A143C656
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1783515:A4E84 RS14420
gene id: 1783515:A4E84_RS14420
uniprot id: A0A143BZK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS20765
gene id: 1783515:A4E84_RS20765
uniprot id: A0A143C2Q3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1783515:A4E84 RS37260
gene id: 1783515:A4E84_RS37260
uniprot id: A0A143CB05
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS00895
gene id: 1783515:A4E84_RS00895
uniprot id: A0A143BTS1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS24920
gene id: 1783515:A4E84_RS24920
uniprot id: A0A143C4Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1783515:A4E84 RS03020
gene id: 1783515:A4E84_RS03020
uniprot id: A0A143BTW7
names: Similarity
messages: Belongs to the PspA/IM30 family.

1783515:A4E84 RS17110
gene id: 1783515:A4E84_RS17110
uniprot id: A0A143C113
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS26255
gene id: 1783515:A4E84_RS26255
uniprot id: A0A143C6T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS22355
gene id: 1783515:A4E84_RS22355
uniprot id: A0A143CDH6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24675
gene id: 1783515:A4E84_RS24675
uniprot id: A0A143C4M8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS00385
gene id: 1783515:A4E84_RS00385
uniprot id: A0A143BTJ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1783515:A4E84 RS03110
gene id: 1783515:A4E84_RS03110
uniprot id: A0A143BTQ0
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS11630
gene id: 1783515:A4E84_RS11630
uniprot id: A0A143BXZ8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1783515:A4E84 RS19700
gene id: 1783515:A4E84_RS19700
uniprot id: A0A143C2X6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS03775
gene id: 1783515:A4E84_RS03775
uniprot id: A0A143BU08
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS33040
gene id: 1783515:A4E84_RS33040
uniprot id: A0A143C8Y5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

1783515:A4E84 RS27790
gene id: 1783515:A4E84_RS27790
uniprot id: A0A143C717
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1783515:A4E84 RS28135
gene id: 1783515:A4E84_RS28135
uniprot id: A0A143C788
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24375
gene id: 1783515:A4E84_RS24375
uniprot id: A0A143C5D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1783515:A4E84 RS25400
gene id: 1783515:A4E84_RS25400
uniprot id: A0A143C4Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1783515:A4E84 RS27665
gene id: 1783515:A4E84_RS27665
uniprot id: A0A143C6A8
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1783515:A4E84 RS15645
gene id: 1783515:A4E84_RS15645
uniprot id: A0A143C188
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1783515:A4E84 RS05860
gene id: 1783515:A4E84_RS05860
uniprot id: A0A143BV14
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1783515:A4E84 RS06440
gene id: 1783515:A4E84_RS06440
uniprot id: A0A143BVJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS38370
gene id: 1783515:A4E84_RS38370
uniprot id: A0A143CBK3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS19935
gene id: 1783515:A4E84_RS19935
uniprot id: A0A143C2G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1783515:A4E84 RS23190
gene id: 1783515:A4E84_RS23190
uniprot id: A0A143C3W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1783515:A4E84 RS18250
gene id: 1783515:A4E84_RS18250
uniprot id: A0A143C2M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1783515:A4E84 RS38660
gene id: 1783515:A4E84_RS38660
uniprot id: A0A143CBS3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1783515:A4E84 RS37800
gene id: 1783515:A4E84_RS37800
uniprot id: A0A143CCL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted
messages: Strong inhibitor of bacterial serine proteases such as subtilisin.

1783515:A4E84 RS09040
gene id: 1783515:A4E84_RS09040
uniprot id: A0A143BWL8
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1783515:A4E84 RS06050
gene id: 1783515:A4E84_RS06050
uniprot id: A0A143BVE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1783515:A4E84 RS36015
gene id: 1783515:A4E84_RS36015
uniprot id: A0A143CB19
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1783515:A4E84 RS34095
gene id: 1783515:A4E84_RS34095
uniprot id: A0A143C9J4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS31555
gene id: 1783515:A4E84_RS31555
uniprot id: A0A143C8V2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS15685
gene id: 1783515:A4E84_RS15685
uniprot id: A0A143C072
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1783515:A4E84 RS01825
gene id: 1783515:A4E84_RS01825
uniprot id: A0A143BSY5
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS07270
gene id: 1783515:A4E84_RS07270
uniprot id: A0A143BW02
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1783515:A4E84 RS21570
gene id: 1783515:A4E84_RS21570
uniprot id: A0A143C432
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1783515:A4E84 RS36705
gene id: 1783515:A4E84_RS36705
uniprot id: A0A143CAW6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1783515:A4E84 RS24760
gene id: 1783515:A4E84_RS24760
uniprot id: A0A143C4Q6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS16455
gene id: 1783515:A4E84_RS16455
uniprot id: A0A143C1K9
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS36880
gene id: 1783515:A4E84_RS36880
uniprot id: A0A143CAU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1783515:A4E84 RS23575
gene id: 1783515:A4E84_RS23575
uniprot id: A0A143C470
names: Similarity
messages: Belongs to the GSP E family.

1783515:A4E84 RS33885
gene id: 1783515:A4E84_RS33885
uniprot id: A0A143CAS8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1783515:A4E84 RS35550
gene id: 1783515:A4E84_RS35550
uniprot id: A0A143CA89
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1783515:A4E84 RS31320
gene id: 1783515:A4E84_RS31320
uniprot id: A0A143C860
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1783515:A4E84 RS28265
gene id: 1783515:A4E84_RS28265
uniprot id: A0A143C7V3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS37155
gene id: 1783515:A4E84_RS37155
uniprot id: A0A143CAX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1783515:A4E84 RS08995
gene id: 1783515:A4E84_RS08995
uniprot id: A0A143BWV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1783515:A4E84 RS35975
gene id: 1783515:A4E84_RS35975
uniprot id: A0A143CAE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1783515:A4E84 RS05960
gene id: 1783515:A4E84_RS05960
uniprot id: A0A143BVA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS31410
gene id: 1783515:A4E84_RS31410
uniprot id: A0A143C873
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1783515:A4E84 RS20720
gene id: 1783515:A4E84_RS20720
uniprot id: A0A143C2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS06745
gene id: 1783515:A4E84_RS06745
uniprot id: A0A143BWD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1783515:A4E84 RS24550
gene id: 1783515:A4E84_RS24550
uniprot id: A0A143C4L4
names: Similarity
messages: Belongs to the YciI family.

1783515:A4E84 RS31370
gene id: 1783515:A4E84_RS31370
uniprot id: A0A143C869
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS13770
gene id: 1783515:A4E84_RS13770
uniprot id: A0A143BZB7
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1783515:A4E84 RS19835
gene id: 1783515:A4E84_RS19835
uniprot id: A0A143C3E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1783515:A4E84 RS38560
gene id: 1783515:A4E84_RS38560
uniprot id: A0A143CC57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1783515:A4E84 RS14575
gene id: 1783515:A4E84_RS14575
uniprot id: A0A143BZV1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS35770
gene id: 1783515:A4E84_RS35770
uniprot id: A0A143CAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

1783515:A4E84 RS45305
gene id: 1783515:A4E84_RS45305
uniprot id: A0A143CBY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS07465
gene id: 1783515:A4E84_RS07465
uniprot id: A0A143BWQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1783515:A4E84 RS23985
gene id: 1783515:A4E84_RS23985
uniprot id: A0A143C4B2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24465
gene id: 1783515:A4E84_RS24465
uniprot id: A0A143C4E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1783515:A4E84 RS14000
gene id: 1783515:A4E84_RS14000
uniprot id: A0A143BZF3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS05315
gene id: 1783515:A4E84_RS05315
uniprot id: A0A143BUZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS38725
gene id: 1783515:A4E84_RS38725
uniprot id: A0A143CBS8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1783515:A4E84 RS13590
gene id: 1783515:A4E84_RS13590
uniprot id: A0A143BYY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1783515:A4E84 RS00965
gene id: 1783515:A4E84_RS00965
uniprot id: A0A143BSW7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS20530
gene id: 1783515:A4E84_RS20530
uniprot id: A0A143C3J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1783515:A4E84 RS20460
gene id: 1783515:A4E84_RS20460
uniprot id: A0A143C2E8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS12445
gene id: 1783515:A4E84_RS12445
uniprot id: A0A143BZH2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1783515:A4E84 RS09550
gene id: 1783515:A4E84_RS09550
uniprot id: A0A143BX59
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS11300
gene id: 1783515:A4E84_RS11300
uniprot id: A0A143BYY3
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1783515:A4E84 RS16775
gene id: 1783515:A4E84_RS16775
uniprot id: A0A143C1R5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

1783515:A4E84 RS30775
gene id: 1783515:A4E84_RS30775
uniprot id: A0A143C7S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS17515
gene id: 1783515:A4E84_RS17515
uniprot id: A0A143C152
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS09895
gene id: 1783515:A4E84_RS09895
uniprot id: A0A143BY53
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS09160
gene id: 1783515:A4E84_RS09160
uniprot id: A0A143BXS0
names: Similarity
messages: Belongs to the peptidase U62 family.

1783515:A4E84 RS25940
gene id: 1783515:A4E84_RS25940
uniprot id: A0A143C611
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS17900
gene id: 1783515:A4E84_RS17900
uniprot id: A0A143C1H0
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1783515:A4E84 RS24015
gene id: 1783515:A4E84_RS24015
uniprot id: A0A143C587
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1783515:A4E84 RS38565
gene id: 1783515:A4E84_RS38565
uniprot id: A0A143CCN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1783515:A4E84 RS23585
gene id: 1783515:A4E84_RS23585
uniprot id: A0A143C443
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS13780
gene id: 1783515:A4E84_RS13780
uniprot id: A0A143BZ22
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1783515:A4E84 RS06315
gene id: 1783515:A4E84_RS06315
uniprot id: A0A143BVJ3
names: Similarity
messages: Belongs to the IMPACT family.

1783515:A4E84 RS07710
gene id: 1783515:A4E84_RS07710
uniprot id: A0A143BX19
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1783515:A4E84 RS03140
gene id: 1783515:A4E84_RS03140
uniprot id: A0A143BUT7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1783515:A4E84 RS05635
gene id: 1783515:A4E84_RS05635
uniprot id: A0A143BW15
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS07190
gene id: 1783515:A4E84_RS07190
uniprot id: A0A143CCQ1
names: Similarity
messages: Belongs to the barstar family.

1783515:A4E84 RS13200
gene id: 1783515:A4E84_RS13200
uniprot id: A0A143BYU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS02440
gene id: 1783515:A4E84_RS02440
uniprot id: A0A143BUB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1783515:A4E84 RS13295
gene id: 1783515:A4E84_RS13295
uniprot id: A0A143BZ41
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS22030
gene id: 1783515:A4E84_RS22030
uniprot id: A0A143C3C3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1783515:A4E84 RS10640
gene id: 1783515:A4E84_RS10640
uniprot id: A0A143BXI6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS37830
gene id: 1783515:A4E84_RS37830
uniprot id: A0A143CCB7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS26060
gene id: 1783515:A4E84_RS26060
uniprot id: A0A143C5C5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1783515:A4E84 RS06135
gene id: 1783515:A4E84_RS06135
uniprot id: A0A143BV29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS36325
gene id: 1783515:A4E84_RS36325
uniprot id: A0A143CAK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS12850
gene id: 1783515:A4E84_RS12850
uniprot id: A0A143BZU6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS24260
gene id: 1783515:A4E84_RS24260
uniprot id: A0A143C4C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1783515:A4E84 RS27420
gene id: 1783515:A4E84_RS27420
uniprot id: A0A143C6W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1783515:A4E84 RS35300
gene id: 1783515:A4E84_RS35300
uniprot id: A0A143CB51
names: Similarity
messages: Belongs to the peptidase M1 family.

1783515:A4E84 RS25540
gene id: 1783515:A4E84_RS25540
uniprot id: A0A143CE04
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1783515:A4E84 RS19240
gene id: 1783515:A4E84_RS19240
uniprot id: A0A143C207
names: Similarity
messages: Belongs to the GARS family.

1783515:A4E84 RS08430
gene id: 1783515:A4E84_RS08430
uniprot id: A0A143BX99
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1783515:A4E84 RS39105
gene id: 1783515:A4E84_RS39105
uniprot id: A0A143CC05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS22650
gene id: 1783515:A4E84_RS22650
uniprot id: A0A143C3P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS09485
gene id: 1783515:A4E84_RS09485
uniprot id: A0A143BX70
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS15045
gene id: 1783515:A4E84_RS15045
uniprot id: A0A143BZQ9
names: Similarity
messages: Belongs to the UPF0303 family.

1783515:A4E84 RS11415
gene id: 1783515:A4E84_RS11415
uniprot id: A0A143BYZ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS00600
gene id: 1783515:A4E84_RS00600
uniprot id: A0A143BSE5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS09320
gene id: 1783515:A4E84_RS09320
uniprot id: A0A143BXP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

1783515:A4E84 RS01690
gene id: 1783515:A4E84_RS01690
uniprot id: A0A143BT06
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS15580
gene id: 1783515:A4E84_RS15580
uniprot id: A0A143C083
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS31215
gene id: 1783515:A4E84_RS31215
uniprot id: A0A143C840
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.

1783515:A4E84 RS30770
gene id: 1783515:A4E84_RS30770
uniprot id: A0A143C7V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS37445
gene id: 1783515:A4E84_RS37445
uniprot id: A0A143CBP3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS07840
gene id: 1783515:A4E84_RS07840
uniprot id: A0A143BW88
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1783515:A4E84 RS25655
gene id: 1783515:A4E84_RS25655
uniprot id: A0A143C5W0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS36780
gene id: 1783515:A4E84_RS36780
uniprot id: A0A143CF04
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS34440
gene id: 1783515:A4E84_RS34440
uniprot id: A0A143CB26
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1783515:A4E84 RS09850
gene id: 1783515:A4E84_RS09850
uniprot id: A0A143BXY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS11095
gene id: 1783515:A4E84_RS11095
uniprot id: A0A143BXN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS07790
gene id: 1783515:A4E84_RS07790
uniprot id: A0A143BX56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1783515:A4E84 RS12170
gene id: 1783515:A4E84_RS12170
uniprot id: A0A143BYH1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS12885
gene id: 1783515:A4E84_RS12885
uniprot id: A0A143BZQ3
names: Similarity
messages: Belongs to the FGGY kinase family.

1783515:A4E84 RS35000
gene id: 1783515:A4E84_RS35000
uniprot id: A0A143CAJ5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1783515:A4E84 RS36280
gene id: 1783515:A4E84_RS36280
uniprot id: A0A143CB55
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

1783515:A4E84 RS28690
gene id: 1783515:A4E84_RS28690
uniprot id: A0A143C6N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1783515:A4E84 RS25040
gene id: 1783515:A4E84_RS25040
uniprot id: A0A143CDZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS13365
gene id: 1783515:A4E84_RS13365
uniprot id: A0A143BYX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1783515:A4E84 RS11355
gene id: 1783515:A4E84_RS11355
uniprot id: A0A143BXU6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1783515:A4E84 RS10105
gene id: 1783515:A4E84_RS10105
uniprot id: A0A143BY35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1783515:A4E84 RS28010
gene id: 1783515:A4E84_RS28010
uniprot id: A0A143CDR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS39160
gene id: 1783515:A4E84_RS39160
uniprot id: A0A143CBY8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS15800
gene id: 1783515:A4E84_RS15800
uniprot id: A0A143C0B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1783515:A4E84 RS08770
gene id: 1783515:A4E84_RS08770
uniprot id: A0A143BWS4
names: Similarity
messages: Belongs to the peptidase S1 family.

1783515:A4E84 RS36330
gene id: 1783515:A4E84_RS36330
uniprot id: A0A143CE18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS07210
gene id: 1783515:A4E84_RS07210
uniprot id: A0A143BWK9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1783515:A4E84 RS01465
gene id: 1783515:A4E84_RS01465
uniprot id: A0A143BSS8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS22605
gene id: 1783515:A4E84_RS22605
uniprot id: A0A143C4J3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS13205
gene id: 1783515:A4E84_RS13205
uniprot id: A0A143BYT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS10405
gene id: 1783515:A4E84_RS10405
uniprot id: A0A143BXJ0
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1783515:A4E84 RS10910
gene id: 1783515:A4E84_RS10910
uniprot id: A0A143BXN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1783515:A4E84 RS06340
gene id: 1783515:A4E84_RS06340
uniprot id: A0A143CCS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1783515:A4E84 RS29570
gene id: 1783515:A4E84_RS29570
uniprot id: A0A143C822
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1783515:A4E84 RS24945
gene id: 1783515:A4E84_RS24945
uniprot id: A0A143C4Z5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1783515:A4E84 RS10705
gene id: 1783515:A4E84_RS10705
uniprot id: A0A143BXI0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1783515:A4E84 RS16345
gene id: 1783515:A4E84_RS16345
uniprot id: A0A143C187
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS09095
gene id: 1783515:A4E84_RS09095
uniprot id: A0A143BWL1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS36515
gene id: 1783515:A4E84_RS36515
uniprot id: A0A143CAN5
names: Similarity
messages: Belongs to the pirin family.

1783515:A4E84 RS25315
gene id: 1783515:A4E84_RS25315
uniprot id: A0A143C5Q5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS01505
gene id: 1783515:A4E84_RS01505
uniprot id: A0A143BT64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M7 family.
messages: Secreted

1783515:A4E84 RS13270
gene id: 1783515:A4E84_RS13270
uniprot id: A0A143BZY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS16555
gene id: 1783515:A4E84_RS16555
uniprot id: A0A143C0M3
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1783515:A4E84 RS20700
gene id: 1783515:A4E84_RS20700
uniprot id: A0A143C3E8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1783515:A4E84 RS27805
gene id: 1783515:A4E84_RS27805
uniprot id: A0A143C6B4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS37915
gene id: 1783515:A4E84_RS37915
uniprot id: A0A143CBC4
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1783515:A4E84 RS19450
gene id: 1783515:A4E84_RS19450
uniprot id: A0A143C312
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS11920
gene id: 1783515:A4E84_RS11920
uniprot id: A0A143BY45
names: Similarity
messages: Belongs to the UPF0246 family.

1783515:A4E84 RS22380
gene id: 1783515:A4E84_RS22380
uniprot id: A0A143C4B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

1783515:A4E84 RS21440
gene id: 1783515:A4E84_RS21440
uniprot id: A0A143C2W6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1783515:A4E84 RS01945
gene id: 1783515:A4E84_RS01945
uniprot id: A0A143BT16
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1783515:A4E84 RS39370
gene id: 1783515:A4E84_RS39370
uniprot id: A0A143CC44
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1783515:A4E84 RS25570
gene id: 1783515:A4E84_RS25570
uniprot id: A0A143C6F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS03295
gene id: 1783515:A4E84_RS03295
uniprot id: A0A143BU09
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS04210
gene id: 1783515:A4E84_RS04210
uniprot id: A0A143BUF6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1783515:A4E84 RS22980
gene id: 1783515:A4E84_RS22980
uniprot id: A0A143C4L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS37925
gene id: 1783515:A4E84_RS37925
uniprot id: A0A143CBD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1783515:A4E84 RS29250
gene id: 1783515:A4E84_RS29250
uniprot id: A0A143C8E1
names: Similarity
messages: Belongs to the WXG100 family.

1783515:A4E84 RS28900
gene id: 1783515:A4E84_RS28900
uniprot id: A0A143C7P9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS28485
gene id: 1783515:A4E84_RS28485
uniprot id: A0A143C6N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1783515:A4E84 RS39230
gene id: 1783515:A4E84_RS39230
uniprot id: A0A143CCJ1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS20780
gene id: 1783515:A4E84_RS20780
uniprot id: A0A143C3Y9
names: Similarity
messages: Belongs to the peptidase S11 family.

1783515:A4E84 RS18760
gene id: 1783515:A4E84_RS18760
uniprot id: A0A143C1I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1783515:A4E84 RS24365
gene id: 1783515:A4E84_RS24365
uniprot id: A0A143C4E6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1783515:A4E84 RS04820
gene id: 1783515:A4E84_RS04820
uniprot id: A0A143BUH5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1783515:A4E84 RS17755
gene id: 1783515:A4E84_RS17755
uniprot id: A0A143C2C9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS37695
gene id: 1783515:A4E84_RS37695
uniprot id: A0A143CCJ9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1783515:A4E84 RS17570
gene id: 1783515:A4E84_RS17570
uniprot id: A0A143C164
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS19245
gene id: 1783515:A4E84_RS19245
uniprot id: A0A143C338
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

1783515:A4E84 RS10975
gene id: 1783515:A4E84_RS10975
uniprot id: A0A143BXP4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1783515:A4E84 RS15000
gene id: 1783515:A4E84_RS15000
uniprot id: A0A143C0R8
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1783515:A4E84 RS43835
gene id: 1783515:A4E84_RS43835
uniprot id: A0A143C322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Secreted

1783515:A4E84 RS38155
gene id: 1783515:A4E84_RS38155
uniprot id: A0A143CFF8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS34475
gene id: 1783515:A4E84_RS34475
uniprot id: A0A143C9N5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS33855
gene id: 1783515:A4E84_RS33855
uniprot id: A0A143C9E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1783515:A4E84 RS37330
gene id: 1783515:A4E84_RS37330
uniprot id: A0A143CBM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS11655
gene id: 1783515:A4E84_RS11655
uniprot id: A0A143BY73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1783515:A4E84 RS12965
gene id: 1783515:A4E84_RS12965
uniprot id: A0A143BYY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1783515:A4E84 RS04955
gene id: 1783515:A4E84_RS04955
uniprot id: A0A143BUI1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1783515:A4E84 RS14425
gene id: 1783515:A4E84_RS14425
uniprot id: A0A143BZM7
names: Similarity
messages: Belongs to the citrate synthase family.

1783515:A4E84 RS23385
gene id: 1783515:A4E84_RS23385
uniprot id: A0A143C4U2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1783515:A4E84 RS26395
gene id: 1783515:A4E84_RS26395
uniprot id: A0A143C5J3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS15340
gene id: 1783515:A4E84_RS15340
uniprot id: A0A143C0M8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1783515:A4E84 RS06240
gene id: 1783515:A4E84_RS06240
uniprot id: A0A143BV89
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1783515:A4E84 RS16435
gene id: 1783515:A4E84_RS16435
uniprot id: A0A143C1P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1783515:A4E84 RS05370
gene id: 1783515:A4E84_RS05370
uniprot id: A0A143BV00
names: Similarity
messages: Belongs to the hyi family.

1783515:A4E84 RS13600
gene id: 1783515:A4E84_RS13600
uniprot id: A0A143BZ26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1783515:A4E84 RS18990
gene id: 1783515:A4E84_RS18990
uniprot id: A0A143C301
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1783515:A4E84 RS27905
gene id: 1783515:A4E84_RS27905
uniprot id: A0A143C743
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1783515:A4E84 RS31480
gene id: 1783515:A4E84_RS31480
uniprot id: A0A143C9H6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS31720
gene id: 1783515:A4E84_RS31720
uniprot id: A0A143C974
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1783515:A4E84 RS23085
gene id: 1783515:A4E84_RS23085
uniprot id: A0A143C583
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1783515:A4E84 RS31265
gene id: 1783515:A4E84_RS31265
uniprot id: A0A143C817
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS13425
gene id: 1783515:A4E84_RS13425
uniprot id: A0A143BYY9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1783515:A4E84 RS22630
gene id: 1783515:A4E84_RS22630
uniprot id: A0A143C3Q4
names: Similarity
messages: Belongs to the group II decarboxylase family.

1783515:A4E84 RS34650
gene id: 1783515:A4E84_RS34650
uniprot id: A0A143CB66
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1783515:A4E84 RS23375
gene id: 1783515:A4E84_RS23375
uniprot id: A0A143C419
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS25695
gene id: 1783515:A4E84_RS25695
uniprot id: A0A143C576
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS17365
gene id: 1783515:A4E84_RS17365
uniprot id: A0A143C140
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1783515:A4E84 RS11510
gene id: 1783515:A4E84_RS11510
uniprot id: A0A143BXX6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1783515:A4E84 RS22660
gene id: 1783515:A4E84_RS22660
uniprot id: A0A143C4G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1783515:A4E84 RS08205
gene id: 1783515:A4E84_RS08205
uniprot id: A0A143BXA4
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1783515:A4E84 RS13480
gene id: 1783515:A4E84_RS13480
uniprot id: A0A143BYW8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS12435
gene id: 1783515:A4E84_RS12435
uniprot id: A0A143BYF7
names: Similarity
messages: Belongs to the CdaR family.

1783515:A4E84 RS29160
gene id: 1783515:A4E84_RS29160
uniprot id: A0A143C7U5
names: Similarity
messages: Belongs to the ribF family.

1783515:A4E84 RS24735
gene id: 1783515:A4E84_RS24735
uniprot id: A0A143C4N8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS11675
gene id: 1783515:A4E84_RS11675
uniprot id: A0A143BY18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS29150
gene id: 1783515:A4E84_RS29150
uniprot id: A0A143C725
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1783515:A4E84 RS17220
gene id: 1783515:A4E84_RS17220
uniprot id: A0A143C106
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1783515:A4E84 RS39275
gene id: 1783515:A4E84_RS39275
uniprot id: A0A143CC36
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS06435
gene id: 1783515:A4E84_RS06435
uniprot id: A0A143BVL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1783515:A4E84 RS28335
gene id: 1783515:A4E84_RS28335
uniprot id: A0A143C799
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS07870
gene id: 1783515:A4E84_RS07870
uniprot id: A0A143BVZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS13855
gene id: 1783515:A4E84_RS13855
uniprot id: A0A143BZX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS15950
gene id: 1783515:A4E84_RS15950
uniprot id: A0A143C196
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS16745
gene id: 1783515:A4E84_RS16745
uniprot id: A0A143C0V0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1783515:A4E84 RS22375
gene id: 1783515:A4E84_RS22375
uniprot id: A0A143C4G3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS29640
gene id: 1783515:A4E84_RS29640
uniprot id: A0A143C766
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1783515:A4E84 RS25500
gene id: 1783515:A4E84_RS25500
uniprot id: A0A143C6E8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1783515:A4E84 RS35155
gene id: 1783515:A4E84_RS35155
uniprot id: A0A143CBF3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS21750
gene id: 1783515:A4E84_RS21750
uniprot id: A0A143C3G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1783515:A4E84 RS08780
gene id: 1783515:A4E84_RS08780
uniprot id: A0A143BWQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1783515:A4E84 RS32270
gene id: 1783515:A4E84_RS32270
uniprot id: A0A143C9U8
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS10750
gene id: 1783515:A4E84_RS10750
uniprot id: A0A143BXK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1783515:A4E84 RS45365
gene id: 1783515:A4E84_RS45365
uniprot id: A0A143C1C0
names: Subcellular Location Annotation
messages: Cytoplasm

1783515:A4E84 RS14770
gene id: 1783515:A4E84_RS14770
uniprot id: A0A143C0M6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1783515:A4E84 RS15520
gene id: 1783515:A4E84_RS15520
uniprot id: A0A143C075
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1783515:A4E84 RS27795
gene id: 1783515:A4E84_RS27795
uniprot id: A0A143C732
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1783515:A4E84 RS30540
gene id: 1783515:A4E84_RS30540
uniprot id: A0A143C8B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1783515:A4E84 RS28515
gene id: 1783515:A4E84_RS28515
uniprot id: A0A143C7D3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1783515:A4E84 RS11525
gene id: 1783515:A4E84_RS11525
uniprot id: A0A143BYS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS31710
gene id: 1783515:A4E84_RS31710
uniprot id: A0A143C8D6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1783515:A4E84 RS04500
gene id: 1783515:A4E84_RS04500
uniprot id: A0A143CCJ8
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS34235
gene id: 1783515:A4E84_RS34235
uniprot id: A0A143C9K0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1783515:A4E84 RS13670
gene id: 1783515:A4E84_RS13670
uniprot id: A0A143BZ40
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1783515:A4E84 RS23450
gene id: 1783515:A4E84_RS23450
uniprot id: A0A143C4Y5
names: Subcellular Location Annotation
messages: Cytoplasm

1783515:A4E84 RS07185
gene id: 1783515:A4E84_RS07185
uniprot id: A0A143CCT2
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

1783515:A4E84 RS18365
gene id: 1783515:A4E84_RS18365
uniprot id: A0A143C2N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

1783515:A4E84 RS17720
gene id: 1783515:A4E84_RS17720
uniprot id: A0A143C173
names: Similarity
messages: Belongs to the FemABX family.

1783515:A4E84 RS35495
gene id: 1783515:A4E84_RS35495
uniprot id: A0A143CA76
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS24085
gene id: 1783515:A4E84_RS24085
uniprot id: A0A143C485
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1783515:A4E84 RS14020
gene id: 1783515:A4E84_RS14020
uniprot id: A0A143BZA1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1783515:A4E84 RS27305
gene id: 1783515:A4E84_RS27305
uniprot id: A0A143C6T3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1783515:A4E84 RS24390
gene id: 1783515:A4E84_RS24390
uniprot id: A0A143C4K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1783515:A4E84 RS17990
gene id: 1783515:A4E84_RS17990
uniprot id: A0A143C161
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1783515:A4E84 RS15535
gene id: 1783515:A4E84_RS15535
uniprot id: A0A143BZY1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS16290
gene id: 1783515:A4E84_RS16290
uniprot id: A0A143C177
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1783515:A4E84 RS22785
gene id: 1783515:A4E84_RS22785
uniprot id: A0A143C533
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

1783515:A4E84 RS18955
gene id: 1783515:A4E84_RS18955
uniprot id: A0A143C2T2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS15435
gene id: 1783515:A4E84_RS15435
uniprot id: A0A143BZW6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS00820
gene id: 1783515:A4E84_RS00820
uniprot id: A0A143BSV0
names: Subcellular Location Annotation
messages: Cytoplasm

1783515:A4E84 RS29580
gene id: 1783515:A4E84_RS29580
uniprot id: A0A143C756
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS00865
gene id: 1783515:A4E84_RS00865
uniprot id: A0A143BSV8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS20580
gene id: 1783515:A4E84_RS20580
uniprot id: A0A143C3K3
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS19945
gene id: 1783515:A4E84_RS19945
uniprot id: A0A143C2B2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1783515:A4E84 RS25625
gene id: 1783515:A4E84_RS25625
uniprot id: A0A143C6H1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS35690
gene id: 1783515:A4E84_RS35690
uniprot id: A0A143CAW3
names: Similarity
messages: Belongs to the CapA family.

1783515:A4E84 RS05955
gene id: 1783515:A4E84_RS05955
uniprot id: A0A143BV99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1783515:A4E84 RS33700
gene id: 1783515:A4E84_RS33700
uniprot id: A0A143C9B0
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

1783515:A4E84 RS37085
gene id: 1783515:A4E84_RS37085
uniprot id: A0A143CB24
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS07040
gene id: 1783515:A4E84_RS07040
uniprot id: A0A143BVW4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS06785
gene id: 1783515:A4E84_RS06785
uniprot id: A0A143BVG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1783515:A4E84 RS11110
gene id: 1783515:A4E84_RS11110
uniprot id: A0A143BY20
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1783515:A4E84 RS21485
gene id: 1783515:A4E84_RS21485
uniprot id: A0A143C4C2
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS07075
gene id: 1783515:A4E84_RS07075
uniprot id: A0A143BVK6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS28195
gene id: 1783515:A4E84_RS28195
uniprot id: A0A143C6L0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS02775
gene id: 1783515:A4E84_RS02775
uniprot id: A0A143BUN6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1783515:A4E84 RS09150
gene id: 1783515:A4E84_RS09150
uniprot id: A0A143BWN9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1783515:A4E84 RS24275
gene id: 1783515:A4E84_RS24275
uniprot id: A0A143C591
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1783515:A4E84 RS15250
gene id: 1783515:A4E84_RS15250
uniprot id: A0A143C023
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1783515:A4E84 RS15990
gene id: 1783515:A4E84_RS15990
uniprot id: A0A143C057
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1783515:A4E84 RS20975
gene id: 1783515:A4E84_RS20975
uniprot id: A0A143CDD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS09230
gene id: 1783515:A4E84_RS09230
uniprot id: A0A143BWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1783515:A4E84 RS33380
gene id: 1783515:A4E84_RS33380
uniprot id: A0A143C968
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS12805
gene id: 1783515:A4E84_RS12805
uniprot id: A0A143BYM1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS39310
gene id: 1783515:A4E84_RS39310
uniprot id: A0A143CC28
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1783515:A4E84 RS16175
gene id: 1783515:A4E84_RS16175
uniprot id: A0A143C0N0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS10775
gene id: 1783515:A4E84_RS10775
uniprot id: A0A143CDW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS03570
gene id: 1783515:A4E84_RS03570
uniprot id: A0A143BTT4
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1783515:A4E84 RS09585
gene id: 1783515:A4E84_RS09585
uniprot id: A0A143BXU0
names: Similarity
messages: Belongs to the DapA family.

1783515:A4E84 RS27810
gene id: 1783515:A4E84_RS27810
uniprot id: A0A143C6A4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS18765
gene id: 1783515:A4E84_RS18765
uniprot id: A0A143C1K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1783515:A4E84 RS30010
gene id: 1783515:A4E84_RS30010
uniprot id: A0A143C7H4
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1783515:A4E84 RS14085
gene id: 1783515:A4E84_RS14085
uniprot id: A0A143BZB0
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1783515:A4E84 RS38180
gene id: 1783515:A4E84_RS38180
uniprot id: A0A143CBK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS10870
gene id: 1783515:A4E84_RS10870
uniprot id: A0A143BYQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS23150
gene id: 1783515:A4E84_RS23150
uniprot id: A0A143C3Q1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1783515:A4E84 RS23760
gene id: 1783515:A4E84_RS23760
uniprot id: A0A143C496
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS31575
gene id: 1783515:A4E84_RS31575
uniprot id: A0A143C896
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS27890
gene id: 1783515:A4E84_RS27890
uniprot id: A0A143C6C4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1783515:A4E84 RS02785
gene id: 1783515:A4E84_RS02785
uniprot id: A0A143BTT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS15510
gene id: 1783515:A4E84_RS15510
uniprot id: A0A143C0B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS24615
gene id: 1783515:A4E84_RS24615
uniprot id: A0A143C4U5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS24010
gene id: 1783515:A4E84_RS24010
uniprot id: A0A143C4D0
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS36300
gene id: 1783515:A4E84_RS36300
uniprot id: A0A143CAK7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1783515:A4E84 RS24490
gene id: 1783515:A4E84_RS24490
uniprot id: A0A143CDF2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1783515:A4E84 RS37105
gene id: 1783515:A4E84_RS37105
uniprot id: A0A143CBI4
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS12255
gene id: 1783515:A4E84_RS12255
uniprot id: A0A143BZI6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS10450
gene id: 1783515:A4E84_RS10450
uniprot id: A0A143BXP5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS22645
gene id: 1783515:A4E84_RS22645
uniprot id: A0A143C3J2
names: Similarity
messages: Belongs to the UPF0145 family.

1783515:A4E84 RS26960
gene id: 1783515:A4E84_RS26960
uniprot id: A0A143C5P0
names: Similarity
messages: Belongs to the YciI family.

1783515:A4E84 RS12470
gene id: 1783515:A4E84_RS12470
uniprot id: A0A143BYP0
names: Similarity
messages: Belongs to the aldose epimerase family.

1783515:A4E84 RS12450
gene id: 1783515:A4E84_RS12450
uniprot id: A0A143BZ80
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1783515:A4E84 RS11450
gene id: 1783515:A4E84_RS11450
uniprot id: A0A143BXY8
names: Similarity
messages: Belongs to the glutamine synthetase family.

1783515:A4E84 RS28505
gene id: 1783515:A4E84_RS28505
uniprot id: A0A143C6M1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1783515:A4E84 RS21805
gene id: 1783515:A4E84_RS21805
uniprot id: A0A143C3D8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1783515:A4E84 RS15035
gene id: 1783515:A4E84_RS15035
uniprot id: A0A143C0Y2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1783515:A4E84 RS03195
gene id: 1783515:A4E84_RS03195
uniprot id: A0A143BTM2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1783515:A4E84 RS10390
gene id: 1783515:A4E84_RS10390
uniprot id: A0A143BY81
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1783515:A4E84 RS07845
gene id: 1783515:A4E84_RS07845
uniprot id: A0A143BX66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1783515:A4E84 RS19715
gene id: 1783515:A4E84_RS19715
uniprot id: A0A143C275
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1783515:A4E84 RS06710
gene id: 1783515:A4E84_RS06710
uniprot id: A0A143BVN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS30445
gene id: 1783515:A4E84_RS30445
uniprot id: A0A143C8J1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS08070
gene id: 1783515:A4E84_RS08070
uniprot id: A0A143BWD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

1783515:A4E84 RS06020
gene id: 1783515:A4E84_RS06020
uniprot id: A0A143BWA6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1783515:A4E84 RS06870
gene id: 1783515:A4E84_RS06870
uniprot id: A0A143BVT4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS33420
gene id: 1783515:A4E84_RS33420
uniprot id: A0A143C981
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

1783515:A4E84 RS29595
gene id: 1783515:A4E84_RS29595
uniprot id: A0A143C757
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1783515:A4E84 RS31585
gene id: 1783515:A4E84_RS31585
uniprot id: A0A143C9I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 4 family.
messages: Secreted

1783515:A4E84 RS23900
gene id: 1783515:A4E84_RS23900
uniprot id: A0A143C434
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS37470
gene id: 1783515:A4E84_RS37470
uniprot id: A0A143CB44
names: Similarity
messages: Belongs to the peptidase S33 family.

1783515:A4E84 RS21500
gene id: 1783515:A4E84_RS21500
uniprot id: A0A143C2Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1783515:A4E84 RS10930
gene id: 1783515:A4E84_RS10930
uniprot id: A0A143BYR6
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1783515:A4E84 RS05575
gene id: 1783515:A4E84_RS05575
uniprot id: A0A143BVR7
names: Similarity
messages: Belongs to the AHA1 family.

1783515:A4E84 RS23715
gene id: 1783515:A4E84_RS23715
uniprot id: A0A143C5J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1783515:A4E84 RS27965
gene id: 1783515:A4E84_RS27965
uniprot id: A0A143C754
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1783515:A4E84 RS21975
gene id: 1783515:A4E84_RS21975
uniprot id: A0A143C4P4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1783515:A4E84 RS34445
gene id: 1783515:A4E84_RS34445
uniprot id: A0A143C9L4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1783515:A4E84 RS14600
gene id: 1783515:A4E84_RS14600
uniprot id: A0A143BZG9
names: Similarity
messages: Belongs to the TPP enzyme family.

1783515:A4E84 RS14975
gene id: 1783515:A4E84_RS14975
uniprot id: A0A143C0X2
names: Similarity
messages: Belongs to the peptidase C40 family.

1783515:A4E84 RS03645
gene id: 1783515:A4E84_RS03645
uniprot id: A0A143BU72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS09275
gene id: 1783515:A4E84_RS09275
uniprot id: A0A143BX32
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1783515:A4E84 RS01290
gene id: 1783515:A4E84_RS01290
uniprot id: A0A143BSQ1
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS30980
gene id: 1783515:A4E84_RS30980
uniprot id: A0A143C7W4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1783515:A4E84 RS25730
gene id: 1783515:A4E84_RS25730
uniprot id: A0A143C6J7
names: Similarity
messages: Belongs to the DSD1 family.

1783515:A4E84 RS28675
gene id: 1783515:A4E84_RS28675
uniprot id: A0A143C6V8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1783515:A4E84 RS19310
gene id: 1783515:A4E84_RS19310
uniprot id: A0A143C1R6
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS25660
gene id: 1783515:A4E84_RS25660
uniprot id: A0A143C5B6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1783515:A4E84 RS28865
gene id: 1783515:A4E84_RS28865
uniprot id: A0A143C6R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1783515:A4E84 RS39415
gene id: 1783515:A4E84_RS39415
uniprot id: A0A143CC48
names: Similarity
messages: Belongs to the terpene synthase family. 2-methylisoborneol synthase subfamily.

1783515:A4E84 RS33440
gene id: 1783515:A4E84_RS33440
uniprot id: A0A143C980
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

1783515:A4E84 RS14090
gene id: 1783515:A4E84_RS14090
uniprot id: A0A143C0B0
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1783515:A4E84 RS38715
gene id: 1783515:A4E84_RS38715
uniprot id: A0A143CBR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1783515:A4E84 RS20930
gene id: 1783515:A4E84_RS20930
uniprot id: A0A143C413
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1783515:A4E84 RS32225
gene id: 1783515:A4E84_RS32225
uniprot id: A0A143C8J8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1783515:A4E84 RS04410
gene id: 1783515:A4E84_RS04410
uniprot id: A0A143BU70
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS31180
gene id: 1783515:A4E84_RS31180
uniprot id: A0A143C7Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1783515:A4E84 RS22795
gene id: 1783515:A4E84_RS22795
uniprot id: A0A143C3J7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS09880
gene id: 1783515:A4E84_RS09880
uniprot id: A0A143BX43
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS36405
gene id: 1783515:A4E84_RS36405
uniprot id: A0A143CB76
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1783515:A4E84 RS15780
gene id: 1783515:A4E84_RS15780
uniprot id: A0A143C0W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1783515:A4E84 RS17520
gene id: 1783515:A4E84_RS17520
uniprot id: A0A143C174
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1783515:A4E84 RS29550
gene id: 1783515:A4E84_RS29550
uniprot id: A0A143C739
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1783515:A4E84 RS35330
gene id: 1783515:A4E84_RS35330
uniprot id: A0A143CBI0
names: Subcellular Location Annotation
messages: Cytoplasm

1783515:A4E84 RS23055
gene id: 1783515:A4E84_RS23055
uniprot id: A0A143C4M4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1783515:A4E84 RS24425
gene id: 1783515:A4E84_RS24425
uniprot id: A0A143C5E6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1783515:A4E84 RS25945
gene id: 1783515:A4E84_RS25945
uniprot id: A0A143C5G9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1783515:A4E84 RS21820
gene id: 1783515:A4E84_RS21820
uniprot id: A0A143C4L6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1783515:A4E84 RS11055
gene id: 1783515:A4E84_RS11055
uniprot id: A0A143CCW7
names: Subcellular Location Annotation
messages: Membrane

1783515:A4E84 RS22990
gene id: 1783515:A4E84_RS22990
uniprot id: A0A143C3Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1783515:A4E84 RS36240
gene id: 1783515:A4E84_RS36240
uniprot id: A0A143CBX2
names: Similarity
messages: Belongs to the pirin family.

1783515:A4E84 RS02675
gene id: 1783515:A4E84_RS02675
uniprot id: A0A143BUF1
names: Similarity
messages: Belongs to the universal stress protein A family.

1783515:A4E84 RS22435
gene id: 1783515:A4E84_RS22435
uniprot id: A0A143C4B9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1783515:A4E84 RS26935
gene id: 1783515:A4E84_RS26935
uniprot id: A0A143C5Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1783515:A4E84 RS34575
gene id: 1783515:A4E84_RS34575
uniprot id: A0A143CAQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1783515:A4E84 RS18740
gene id: 1783515:A4E84_RS18740
uniprot id: A0A143CD71
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).