178339:BH719 RS08550
gene id: 178339:BH719_RS08550
uniprot id: A0A1D8B450
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

178339:BH719 RS09805
gene id: 178339:BH719_RS09805
uniprot id: A0A1D8B1K5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

178339:BH719 RS01825
gene id: 178339:BH719_RS01825
uniprot id: A0A1D8B4B2
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS02835
gene id: 178339:BH719_RS02835
uniprot id: A0A1D8B1B3
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.

178339:BH719 RS05485
gene id: 178339:BH719_RS05485
uniprot id: A0A1D8B2M7
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

178339:BH719 RS07365
gene id: 178339:BH719_RS07365
uniprot id: A0A1D8B3H7
names: Similarity
messages: Belongs to the peptidase C40 family.

178339:BH719 RS02090
gene id: 178339:BH719_RS02090
uniprot id: A0A1D8B0Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

178339:BH719 RS04235
gene id: 178339:BH719_RS04235
uniprot id: A0A1D8B207
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

178339:BH719 RS04845
gene id: 178339:BH719_RS04845
uniprot id: A0A1D8B2A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS01295
gene id: 178339:BH719_RS01295
uniprot id: A0A1D8B0K9
names: Similarity
messages: Belongs to the FemABX family.

178339:BH719 RS03235
gene id: 178339:BH719_RS03235
uniprot id: A0A1D8B1K2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

178339:BH719 RS08420
gene id: 178339:BH719_RS08420
uniprot id: A0A1D8B430
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

178339:BH719 RS04420
gene id: 178339:BH719_RS04420
uniprot id: A0A1D8B257
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

178339:BH719 RS05230
gene id: 178339:BH719_RS05230
uniprot id: A0A1D8B2K4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

178339:BH719 RS02755
gene id: 178339:BH719_RS02755
uniprot id: A0A1D8B195
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

178339:BH719 RS01500
gene id: 178339:BH719_RS01500
uniprot id: A0A1D8B0P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

178339:BH719 RS05445
gene id: 178339:BH719_RS05445
uniprot id: A0A1D8B2L5
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS02145
gene id: 178339:BH719_RS02145
uniprot id: A0A1D8B107
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

178339:BH719 RS08520
gene id: 178339:BH719_RS08520
uniprot id: A0A1D8B412
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

178339:BH719 RS03130
gene id: 178339:BH719_RS03130
uniprot id: A0A1D8B1F6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

178339:BH719 RS04220
gene id: 178339:BH719_RS04220
uniprot id: A0A1D8B1Y8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

178339:BH719 RS00820
gene id: 178339:BH719_RS00820
uniprot id: A0A1D8B0E4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

178339:BH719 RS04445
gene id: 178339:BH719_RS04445
uniprot id: A0A1D8B226
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

178339:BH719 RS04245
gene id: 178339:BH719_RS04245
uniprot id: A0A1D8B202
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

178339:BH719 RS03155
gene id: 178339:BH719_RS03155
uniprot id: A0A1D8B1F5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

178339:BH719 RS07275
gene id: 178339:BH719_RS07275
uniprot id: A0A1D8B3E3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

178339:BH719 RS02680
gene id: 178339:BH719_RS02680
uniprot id: A0A1D8B193
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

178339:BH719 RS05160
gene id: 178339:BH719_RS05160
uniprot id: A0A1D8B2I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

178339:BH719 RS04730
gene id: 178339:BH719_RS04730
uniprot id: A0A1D8B287
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

178339:BH719 RS01220
gene id: 178339:BH719_RS01220
uniprot id: A0A1D8B0I8
names: Similarity
messages: Belongs to the glutamine synthetase family.

178339:BH719 RS02200
gene id: 178339:BH719_RS02200
uniprot id: A0A1D8B0Z3
names: Similarity
messages: Belongs to the peptidase M16 family.

178339:BH719 RS04510
gene id: 178339:BH719_RS04510
uniprot id: A0A1D8B240
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

178339:BH719 RS00105
gene id: 178339:BH719_RS00105
uniprot id: A0A1D8B028
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS07575
gene id: 178339:BH719_RS07575
uniprot id: A0A1D8B3J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

178339:BH719 RS04150
gene id: 178339:BH719_RS04150
uniprot id: A0A1D8B1X8
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS05040
gene id: 178339:BH719_RS05040
uniprot id: A0A1D8B2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

178339:BH719 RS02005
gene id: 178339:BH719_RS02005
uniprot id: A0A1D8B0Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

178339:BH719 RS02275
gene id: 178339:BH719_RS02275
uniprot id: A0A1D8B121
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

178339:BH719 RS00385
gene id: 178339:BH719_RS00385
uniprot id: A0A1D8B093
names: Similarity
messages: Belongs to the prokaryotic ubiquitin-like protein family.

178339:BH719 RS02215
gene id: 178339:BH719_RS02215
uniprot id: A0A1D8B119
names: Similarity
messages: Belongs to the ribF family.

178339:BH719 RS07255
gene id: 178339:BH719_RS07255
uniprot id: A0A1D8B3F2
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS03750
gene id: 178339:BH719_RS03750
uniprot id: A0A1D8B1Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

178339:BH719 RS06710
gene id: 178339:BH719_RS06710
uniprot id: A0A1D8B368
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS02280
gene id: 178339:BH719_RS02280
uniprot id: A0A1D8B120
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

178339:BH719 RS00015
gene id: 178339:BH719_RS00015
uniprot id: A0A1D8B014
names: Similarity
messages: Belongs to the TlyA family.

178339:BH719 RS07335
gene id: 178339:BH719_RS07335
uniprot id: A0A1D8B3G9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

178339:BH719 RS04400
gene id: 178339:BH719_RS04400
uniprot id: A0A1D8B216
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

178339:BH719 RS08505
gene id: 178339:BH719_RS08505
uniprot id: A0A1D8B3Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

178339:BH719 RS04535
gene id: 178339:BH719_RS04535
uniprot id: A0A1D8B245
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

178339:BH719 RS01905
gene id: 178339:BH719_RS01905
uniprot id: A0A1D8B0V9
names: Subcellular Location Annotation
messages: Cytoplasm

178339:BH719 RS10030
gene id: 178339:BH719_RS10030
uniprot id: A0A1D8B1N4
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

178339:BH719 RS08900
gene id: 178339:BH719_RS08900
uniprot id: A0A1D8B471
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS02165
gene id: 178339:BH719_RS02165
uniprot id: A0A1D8B131
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

178339:BH719 RS03395
gene id: 178339:BH719_RS03395
uniprot id: A0A1D8B1J0
names: Similarity
messages: Belongs to the glutamine synthetase family.

178339:BH719 RS01745
gene id: 178339:BH719_RS01745
uniprot id: A0A1D8B0V0
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

178339:BH719 RS00950
gene id: 178339:BH719_RS00950
uniprot id: A0A1D8B0F4
names: Similarity
messages: Belongs to the TrpC family.

178339:BH719 RS03225
gene id: 178339:BH719_RS03225
uniprot id: A0A1D8B1H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

178339:BH719 RS02410
gene id: 178339:BH719_RS02410
uniprot id: A0A1D8B139
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

178339:BH719 RS01725
gene id: 178339:BH719_RS01725
uniprot id: A0A1D8B0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

178339:BH719 RS08545
gene id: 178339:BH719_RS08545
uniprot id: A0A1D8B409
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

178339:BH719 RS07735
gene id: 178339:BH719_RS07735
uniprot id: A0A1D8B3N0
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

178339:BH719 RS01990
gene id: 178339:BH719_RS01990
uniprot id: A0A1D8B4A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

178339:BH719 RS06600
gene id: 178339:BH719_RS06600
uniprot id: A0A1D8B338
names: Similarity
messages: Belongs to the ParB family.

178339:BH719 RS07665
gene id: 178339:BH719_RS07665
uniprot id: A0A1D8B3M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

178339:BH719 RS02880
gene id: 178339:BH719_RS02880
uniprot id: A0A1D8B1C4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

178339:BH719 RS04770
gene id: 178339:BH719_RS04770
uniprot id: A0A1D8B297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

178339:BH719 RS04485
gene id: 178339:BH719_RS04485
uniprot id: A0A1D8B238
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

178339:BH719 RS04520
gene id: 178339:BH719_RS04520
uniprot id: A0A1D8B269
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

178339:BH719 RS07145
gene id: 178339:BH719_RS07145
uniprot id: A0A1D8B3B9
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS04735
gene id: 178339:BH719_RS04735
uniprot id: A0A1D8B294
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS01090
gene id: 178339:BH719_RS01090
uniprot id: A0A1D8B0I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

178339:BH719 RS08180
gene id: 178339:BH719_RS08180
uniprot id: A0A1D8B3V0
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS01290
gene id: 178339:BH719_RS01290
uniprot id: A0A1D8B0Q1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS08525
gene id: 178339:BH719_RS08525
uniprot id: A0A1D8B404
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

178339:BH719 RS06650
gene id: 178339:BH719_RS06650
uniprot id: A0A1D8B345
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

178339:BH719 RS04265
gene id: 178339:BH719_RS04265
uniprot id: A0A1D8B1Z7
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

178339:BH719 RS04075
gene id: 178339:BH719_RS04075
uniprot id: A0A1D8B1W4
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

178339:BH719 RS08060
gene id: 178339:BH719_RS08060
uniprot id: A0A1D8B3S4
names: Similarity
messages: Belongs to the peptidase S8 family.

178339:BH719 RS06490
gene id: 178339:BH719_RS06490
uniprot id: A0A1D8B323
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS04440
gene id: 178339:BH719_RS04440
uniprot id: A0A1D8B236
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

178339:BH719 RS04575
gene id: 178339:BH719_RS04575
uniprot id: A0A1D8B255
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

178339:BH719 RS06760
gene id: 178339:BH719_RS06760
uniprot id: A0A1D8B381
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

178339:BH719 RS01185
gene id: 178339:BH719_RS01185
uniprot id: A0A1D8B0J3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

178339:BH719 RS07960
gene id: 178339:BH719_RS07960
uniprot id: A0A1D8B3S5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

178339:BH719 RS01770
gene id: 178339:BH719_RS01770
uniprot id: A0A1D8B0U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

178339:BH719 RS01370
gene id: 178339:BH719_RS01370
uniprot id: A0A1D8B498
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS04000
gene id: 178339:BH719_RS04000
uniprot id: A0A1D8B1V7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

178339:BH719 RS00335
gene id: 178339:BH719_RS00335
uniprot id: A0A1D8B070
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS01995
gene id: 178339:BH719_RS01995
uniprot id: A0A1D8B0W2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

178339:BH719 RS01890
gene id: 178339:BH719_RS01890
uniprot id: A0A1D8B0Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

178339:BH719 RS06565
gene id: 178339:BH719_RS06565
uniprot id: A0A1D8B327
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

178339:BH719 RS02385
gene id: 178339:BH719_RS02385
uniprot id: A0A1D8B161
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

178339:BH719 RS02475
gene id: 178339:BH719_RS02475
uniprot id: A0A1D8B147
names: Similarity
messages: Belongs to the ABC transporter superfamily.

178339:BH719 RS02035
gene id: 178339:BH719_RS02035
uniprot id: A0A1D8B0Y7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

178339:BH719 RS02025
gene id: 178339:BH719_RS02025
uniprot id: A0A1D8B0Y0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

178339:BH719 RS03300
gene id: 178339:BH719_RS03300
uniprot id: A0A1D8B1J1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

178339:BH719 RS00960
gene id: 178339:BH719_RS00960
uniprot id: A0A1D8B0E9
names: Similarity
messages: Belongs to the peptidase A24 family.

178339:BH719 RS04455
gene id: 178339:BH719_RS04455
uniprot id: A0A1D8B223
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

178339:BH719 RS02575
gene id: 178339:BH719_RS02575
uniprot id: A0A1D8B160
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

178339:BH719 RS00215
gene id: 178339:BH719_RS00215
uniprot id: A0A1D8B054
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

178339:BH719 RS04470
gene id: 178339:BH719_RS04470
uniprot id: A0A1D8B261
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

178339:BH719 RS02890
gene id: 178339:BH719_RS02890
uniprot id: A0A1D8B1C3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

178339:BH719 RS00140
gene id: 178339:BH719_RS00140
uniprot id: A0A1D8B056
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

178339:BH719 RS02380
gene id: 178339:BH719_RS02380
uniprot id: A0A1D8B4B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

178339:BH719 RS06055
gene id: 178339:BH719_RS06055
uniprot id: A0A1D8B2U9
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS03465
gene id: 178339:BH719_RS03465
uniprot id: A0A1D8B4D8
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS04430
gene id: 178339:BH719_RS04430
uniprot id: A0A1D8B243
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

178339:BH719 RS06300
gene id: 178339:BH719_RS06300
uniprot id: A0A1D8B300
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS02270
gene id: 178339:BH719_RS02270
uniprot id: A0A1D8B103
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS03025
gene id: 178339:BH719_RS03025
uniprot id: A0A1D8B1E0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

178339:BH719 RS08170
gene id: 178339:BH719_RS08170
uniprot id: A0A1D8B3V3
names: Similarity
messages: Belongs to the UPF0423 family.

178339:BH719 RS01845
gene id: 178339:BH719_RS01845
uniprot id: A0A1D8B0U3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

178339:BH719 RS04715
gene id: 178339:BH719_RS04715
uniprot id: A0A1D8B275
names: Similarity
messages: Belongs to the universal stress protein A family.

178339:BH719 RS05335
gene id: 178339:BH719_RS05335
uniprot id: A0A1D8B2H8
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS04585
gene id: 178339:BH719_RS04585
uniprot id: A0A1D8B252
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

178339:BH719 RS08780
gene id: 178339:BH719_RS08780
uniprot id: A0A1D8B448
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

178339:BH719 RS00235
gene id: 178339:BH719_RS00235
uniprot id: A0A1D8B065
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

178339:BH719 RS02360
gene id: 178339:BH719_RS02360
uniprot id: A0A1D8B135
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

178339:BH719 RS03980
gene id: 178339:BH719_RS03980
uniprot id: A0A1D8B1V3
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS05680
gene id: 178339:BH719_RS05680
uniprot id: A0A1D8B2P5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

178339:BH719 RS06295
gene id: 178339:BH719_RS06295
uniprot id: A0A1D8B2Z3
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS04540
gene id: 178339:BH719_RS04540
uniprot id: A0A1D8B247
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

178339:BH719 RS01125
gene id: 178339:BH719_RS01125
uniprot id: A0A1D8B0M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

178339:BH719 RS02560
gene id: 178339:BH719_RS02560
uniprot id: A0A1D8B189
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS06640
gene id: 178339:BH719_RS06640
uniprot id: A0A1D8B343
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

178339:BH719 RS06590
gene id: 178339:BH719_RS06590
uniprot id: A0A1D8B350
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

178339:BH719 RS00500
gene id: 178339:BH719_RS00500
uniprot id: A0A1D8B0A1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

178339:BH719 RS05740
gene id: 178339:BH719_RS05740
uniprot id: A0A1D8B2N5
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

178339:BH719 RS02240
gene id: 178339:BH719_RS02240
uniprot id: A0A1D8B109
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

178339:BH719 RS03720
gene id: 178339:BH719_RS03720
uniprot id: A0A1D8B1R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

178339:BH719 RS06800
gene id: 178339:BH719_RS06800
uniprot id: A0A1D8B395
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

178339:BH719 RS02670
gene id: 178339:BH719_RS02670
uniprot id: A0A1D8B1B2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

178339:BH719 RS04780
gene id: 178339:BH719_RS04780
uniprot id: A0A1D8B291
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

178339:BH719 RS01180
gene id: 178339:BH719_RS01180
uniprot id: A0A1D8B0N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

178339:BH719 RS06455
gene id: 178339:BH719_RS06455
uniprot id: A0A1D8B333
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

178339:BH719 RS03345
gene id: 178339:BH719_RS03345
uniprot id: A0A1D8B1J4
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

178339:BH719 RS07290
gene id: 178339:BH719_RS07290
uniprot id: A0A1D8B3E6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

178339:BH719 RS08485
gene id: 178339:BH719_RS08485
uniprot id: A0A1D8B401
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

178339:BH719 RS04165
gene id: 178339:BH719_RS04165
uniprot id: A0A1D8B1X6
names: Similarity
messages: Belongs to the BMP lipoprotein family.

178339:BH719 RS02480
gene id: 178339:BH719_RS02480
uniprot id: A0A1D8B145
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS03725
gene id: 178339:BH719_RS03725
uniprot id: A0A1D8B1R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

178339:BH719 RS02255
gene id: 178339:BH719_RS02255
uniprot id: A0A1D8B134
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

178339:BH719 RS02590
gene id: 178339:BH719_RS02590
uniprot id: A0A1D8B176
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

178339:BH719 RS07040
gene id: 178339:BH719_RS07040
uniprot id: A0A1D8B3C2
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

178339:BH719 RS05125
gene id: 178339:BH719_RS05125
uniprot id: A0A1D8B2F8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS03440
gene id: 178339:BH719_RS03440
uniprot id: A0A1D8B1L7
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS07495
gene id: 178339:BH719_RS07495
uniprot id: A0A1D8B3J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS04695
gene id: 178339:BH719_RS04695
uniprot id: A0A1D8B278
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

178339:BH719 RS00745
gene id: 178339:BH719_RS00745
uniprot id: A0A1D8B0E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

178339:BH719 RS07920
gene id: 178339:BH719_RS07920
uniprot id: A0A1D8B3Q6
names: Similarity
messages: Belongs to the MT-A70-like family.

178339:BH719 RS03760
gene id: 178339:BH719_RS03760
uniprot id: A0A1D8B1U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

178339:BH719 RS01960
gene id: 178339:BH719_RS01960
uniprot id: A0A1D8B0V4
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS00880
gene id: 178339:BH719_RS00880
uniprot id: A0A1D8B0E3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

178339:BH719 RS03030
gene id: 178339:BH719_RS03030
uniprot id: A0A1D8B1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

178339:BH719 RS08050
gene id: 178339:BH719_RS08050
uniprot id: A0A1D8B3W5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

178339:BH719 RS01690
gene id: 178339:BH719_RS01690
uniprot id: A0A1D8B0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

178339:BH719 RS04480
gene id: 178339:BH719_RS04480
uniprot id: A0A1D8B253
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

178339:BH719 RS00555
gene id: 178339:BH719_RS00555
uniprot id: A0A1D8B0B1
names: Similarity
messages: Belongs to the Fmt family.

178339:BH719 RS08515
gene id: 178339:BH719_RS08515
uniprot id: A0A1D8B415
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

178339:BH719 RS00510
gene id: 178339:BH719_RS00510
uniprot id: A0A1D8B0C0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS03965
gene id: 178339:BH719_RS03965
uniprot id: A0A1D8B4E8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

178339:BH719 RS03330
gene id: 178339:BH719_RS03330
uniprot id: A0A1D8B1J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

178339:BH719 RS08280
gene id: 178339:BH719_RS08280
uniprot id: A0A1D8B3X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

178339:BH719 RS00240
gene id: 178339:BH719_RS00240
uniprot id: A0A1D8B063
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

178339:BH719 RS00740
gene id: 178339:BH719_RS00740
uniprot id: A0A1D8B0C1
names: Similarity
messages: Belongs to the UPF0098 family.

178339:BH719 RS08160
gene id: 178339:BH719_RS08160
uniprot id: A0A1D8B3Y4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

178339:BH719 RS07855
gene id: 178339:BH719_RS07855
uniprot id: A0A1D8B3Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS06050
gene id: 178339:BH719_RS06050
uniprot id: A0A1D8B2V6
names: Similarity
messages: Belongs to the CsoR family.

178339:BH719 RS04350
gene id: 178339:BH719_RS04350
uniprot id: A0A1D8B4H3
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

178339:BH719 RS01440
gene id: 178339:BH719_RS01440
uniprot id: A0A1D8B0N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

178339:BH719 RS00525
gene id: 178339:BH719_RS00525
uniprot id: A0A1D8B099
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

178339:BH719 RS08255
gene id: 178339:BH719_RS08255
uniprot id: A0A1D8B3W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

178339:BH719 RS08625
gene id: 178339:BH719_RS08625
uniprot id: A0A1D8B423
names: Similarity
messages: Belongs to the DapA family.

178339:BH719 RS03365
gene id: 178339:BH719_RS03365
uniprot id: A0A1D8B1L1
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

178339:BH719 RS08570
gene id: 178339:BH719_RS08570
uniprot id: A0A1D8B425
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

178339:BH719 RS01915
gene id: 178339:BH719_RS01915
uniprot id: A0A1D8B0V6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

178339:BH719 RS04550
gene id: 178339:BH719_RS04550
uniprot id: A0A1D8B256
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

178339:BH719 RS00230
gene id: 178339:BH719_RS00230
uniprot id: A0A1D8B047
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

178339:BH719 RS03290
gene id: 178339:BH719_RS03290
uniprot id: A0A1D8B1I2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

178339:BH719 RS03270
gene id: 178339:BH719_RS03270
uniprot id: A0A1D8B1I5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

178339:BH719 RS01970
gene id: 178339:BH719_RS01970
uniprot id: A0A1D8B0W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

178339:BH719 RS02855
gene id: 178339:BH719_RS02855
uniprot id: A0A1D8B1A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS04450
gene id: 178339:BH719_RS04450
uniprot id: A0A1D8B241
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

178339:BH719 RS05365
gene id: 178339:BH719_RS05365
uniprot id: A0A1D8B2K7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

178339:BH719 RS00360
gene id: 178339:BH719_RS00360
uniprot id: A0A1D8B483
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

178339:BH719 RS06815
gene id: 178339:BH719_RS06815
uniprot id: A0A1D8B4H5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

178339:BH719 RS05675
gene id: 178339:BH719_RS05675
uniprot id: A0A1D8B2R1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS07480
gene id: 178339:BH719_RS07480
uniprot id: A0A1D8B3J0
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS02510
gene id: 178339:BH719_RS02510
uniprot id: A0A1D8B150
names: Similarity
messages: Belongs to the peptidase C15 family.

178339:BH719 RS01730
gene id: 178339:BH719_RS01730
uniprot id: A0A1D8B0S5
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS00260
gene id: 178339:BH719_RS00260
uniprot id: A0A1D8B067
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS06550
gene id: 178339:BH719_RS06550
uniprot id: A0A1D8B336
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS05515
gene id: 178339:BH719_RS05515
uniprot id: A0A1D8B2M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

178339:BH719 RS03840
gene id: 178339:BH719_RS03840
uniprot id: A0A1D8B1S9
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

178339:BH719 RS08555
gene id: 178339:BH719_RS08555
uniprot id: A0A1D8B414
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

178339:BH719 RS06380
gene id: 178339:BH719_RS06380
uniprot id: A0A1D8B319
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

178339:BH719 RS07535
gene id: 178339:BH719_RS07535
uniprot id: A0A1D8B3K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

178339:BH719 RS00380
gene id: 178339:BH719_RS00380
uniprot id: A0A1D8B084
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

178339:BH719 RS03295
gene id: 178339:BH719_RS03295
uniprot id: A0A1D8B1L3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

178339:BH719 RS05380
gene id: 178339:BH719_RS05380
uniprot id: A0A1D8B2J7
names: Similarity
messages: Belongs to the GARS family.

178339:BH719 RS02625
gene id: 178339:BH719_RS02625
uniprot id: A0A1D8B178
names: Similarity
messages: Belongs to the ABC transporter superfamily.

178339:BH719 RS07210
gene id: 178339:BH719_RS07210
uniprot id: A0A1D8B3H8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

178339:BH719 RS07860
gene id: 178339:BH719_RS07860
uniprot id: A0A1D8B3Q5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

178339:BH719 RS04725
gene id: 178339:BH719_RS04725
uniprot id: A0A1D8B298
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

178339:BH719 RS01855
gene id: 178339:BH719_RS01855
uniprot id: A0A1D8B0U7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

178339:BH719 RS07765
gene id: 178339:BH719_RS07765
uniprot id: A0A1D8B3R0
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS02825
gene id: 178339:BH719_RS02825
uniprot id: A0A1D8B1B4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

178339:BH719 RS05185
gene id: 178339:BH719_RS05185
uniprot id: A0A1D8B2H2
names: Subcellular Location Annotation
messages: Cell membrane

178339:BH719 RS08480
gene id: 178339:BH719_RS08480
uniprot id: A0A1D8B3Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

178339:BH719 RS06620
gene id: 178339:BH719_RS06620
uniprot id: A0A1D8B339
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

178339:BH719 RS03340
gene id: 178339:BH719_RS03340
uniprot id: A0A1D8B1I0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

178339:BH719 RS07285
gene id: 178339:BH719_RS07285
uniprot id: A0A1D8B3F9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

178339:BH719 RS05210
gene id: 178339:BH719_RS05210
uniprot id: A0A1D8B2H6
names: Function
names: Similarity
messages: Belongs to the GrpE family.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

178339:BH719 RS05800
gene id: 178339:BH719_RS05800
uniprot id: A0A1D8B2P0
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS08355
gene id: 178339:BH719_RS08355
uniprot id: A0A1D8B3Z0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

178339:BH719 RS04340
gene id: 178339:BH719_RS04340
uniprot id: A0A1D8B208
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

178339:BH719 RS01245
gene id: 178339:BH719_RS01245
uniprot id: A0A1D8B0K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

178339:BH719 RS03035
gene id: 178339:BH719_RS03035
uniprot id: A0A1D8B1E1
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS01700
gene id: 178339:BH719_RS01700
uniprot id: A0A1D8B0S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

178339:BH719 RS06115
gene id: 178339:BH719_RS06115
uniprot id: A0A1D8B2V7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

178339:BH719 RS05435
gene id: 178339:BH719_RS05435
uniprot id: A0A1D8B2K8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

178339:BH719 RS00660
gene id: 178339:BH719_RS00660
uniprot id: A0A1D8B0B6
names: Similarity
messages: Belongs to the UPF0749 family.

178339:BH719 RS05000
gene id: 178339:BH719_RS05000
uniprot id: A0A1D8B2E2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

178339:BH719 RS02470
gene id: 178339:BH719_RS02470
uniprot id: A0A1D8B152
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

178339:BH719 RS05690
gene id: 178339:BH719_RS05690
uniprot id: A0A1D8B2Q5
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS04395
gene id: 178339:BH719_RS04395
uniprot id: A0A1D8B230
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

178339:BH719 RS06625
gene id: 178339:BH719_RS06625
uniprot id: A0A1D8B331
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

178339:BH719 RS06265
gene id: 178339:BH719_RS06265
uniprot id: A0A1D8B305
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS04505
gene id: 178339:BH719_RS04505
uniprot id: A0A1D8B233
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

178339:BH719 RS03135
gene id: 178339:BH719_RS03135
uniprot id: A0A1D8B1G4
names: Similarity
messages: Belongs to the peptidase S8 family.

178339:BH719 RS02760
gene id: 178339:BH719_RS02760
uniprot id: A0A1D8B1A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

178339:BH719 RS08815
gene id: 178339:BH719_RS08815
uniprot id: A0A1D8B486
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS08435
gene id: 178339:BH719_RS08435
uniprot id: A0A1D8B3Z4
names: Similarity
messages: Belongs to the peptidase S1C family.

178339:BH719 RS03020
gene id: 178339:BH719_RS03020
uniprot id: A0A1D8B1E3
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS08725
gene id: 178339:BH719_RS08725
uniprot id: A0A1D8B433
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

178339:BH719 RS01965
gene id: 178339:BH719_RS01965
uniprot id: A0A1D8B0X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

178339:BH719 RS02315
gene id: 178339:BH719_RS02315
uniprot id: A0A1D8B115
names: Similarity
messages: Belongs to the malic enzymes family.

178339:BH719 RS01535
gene id: 178339:BH719_RS01535
uniprot id: A0A1D8B0P9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

178339:BH719 RS01680
gene id: 178339:BH719_RS01680
uniprot id: A0A1D8B4D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

178339:BH719 RS02730
gene id: 178339:BH719_RS02730
uniprot id: A0A1D8B1B0
names: Similarity
messages: Belongs to the heat shock protein 90 family.

178339:BH719 RS05685
gene id: 178339:BH719_RS05685
uniprot id: A0A1D8B2Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

178339:BH719 RS02320
gene id: 178339:BH719_RS02320
uniprot id: A0A1D8B114
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

178339:BH719 RS04335
gene id: 178339:BH719_RS04335
uniprot id: A0A1D8B218
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

178339:BH719 RS00505
gene id: 178339:BH719_RS00505
uniprot id: A0A1D8B095
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

178339:BH719 RS02115
gene id: 178339:BH719_RS02115
uniprot id: A0A1D8B123
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS04600
gene id: 178339:BH719_RS04600
uniprot id: A0A1D8B265
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

178339:BH719 RS07515
gene id: 178339:BH719_RS07515
uniprot id: A0A1D8B3J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

178339:BH719 RS00515
gene id: 178339:BH719_RS00515
uniprot id: A0A1D8B0A4
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

178339:BH719 RS01360
gene id: 178339:BH719_RS01360
uniprot id: A0A1D8B0Q0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

178339:BH719 RS03390
gene id: 178339:BH719_RS03390
uniprot id: A0A1D8B1J9
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS06425
gene id: 178339:BH719_RS06425
uniprot id: A0A1D8B317
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

178339:BH719 RS08370
gene id: 178339:BH719_RS08370
uniprot id: A0A1D8B420
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

178339:BH719 RS00415
gene id: 178339:BH719_RS00415
uniprot id: A0A1D8B075
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

178339:BH719 RS03960
gene id: 178339:BH719_RS03960
uniprot id: A0A1D8B1W3
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

178339:BH719 RS04490
gene id: 178339:BH719_RS04490
uniprot id: A0A1D8B244
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

178339:BH719 RS06680
gene id: 178339:BH719_RS06680
uniprot id: A0A1D8B344
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

178339:BH719 RS08510
gene id: 178339:BH719_RS08510
uniprot id: A0A1D8B411
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

178339:BH719 RS01590
gene id: 178339:BH719_RS01590
uniprot id: A0A1D8B0R7
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS07905
gene id: 178339:BH719_RS07905
uniprot id: A0A1D8B3R3
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

178339:BH719 RS06860
gene id: 178339:BH719_RS06860
uniprot id: A0A1D8B388
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

178339:BH719 RS08590
gene id: 178339:BH719_RS08590
uniprot id: A0A1D8B4M7
names: Similarity
messages: Belongs to the UPF0234 family.

178339:BH719 RS06735
gene id: 178339:BH719_RS06735
uniprot id: A0A1D8B357
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

178339:BH719 RS07910
gene id: 178339:BH719_RS07910
uniprot id: A0A1D8B3R5
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS01810
gene id: 178339:BH719_RS01810
uniprot id: A0A1D8B0X4
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS06440
gene id: 178339:BH719_RS06440
uniprot id: A0A1D8B303
names: Similarity
messages: Belongs to the FGGY kinase family.

178339:BH719 RS00535
gene id: 178339:BH719_RS00535
uniprot id: A0A1D8B090
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS03680
gene id: 178339:BH719_RS03680
uniprot id: A0A1D8B1P3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

178339:BH719 RS04145
gene id: 178339:BH719_RS04145
uniprot id: A0A1D8B1X5
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

178339:BH719 RS08365
gene id: 178339:BH719_RS08365
uniprot id: A0A1D8B3X7
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS01095
gene id: 178339:BH719_RS01095
uniprot id: A0A1D8B0H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

178339:BH719 RS04010
gene id: 178339:BH719_RS04010
uniprot id: A0A1D8B1X0
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS02845
gene id: 178339:BH719_RS02845
uniprot id: A0A1D8B1B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

178339:BH719 RS02650
gene id: 178339:BH719_RS02650
uniprot id: A0A1D8B175
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

178339:BH719 RS08580
gene id: 178339:BH719_RS08580
uniprot id: A0A1D8B413
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

178339:BH719 RS02780
gene id: 178339:BH719_RS02780
uniprot id: A0A1D8B1C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

178339:BH719 RS08530
gene id: 178339:BH719_RS08530
uniprot id: A0A1D8B424
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

178339:BH719 RS03870
gene id: 178339:BH719_RS03870
uniprot id: A0A1D8B4G7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

178339:BH719 RS03335
gene id: 178339:BH719_RS03335
uniprot id: A0A1D8B1I9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS04555
gene id: 178339:BH719_RS04555
uniprot id: A0A1D8B248
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

178339:BH719 RS05605
gene id: 178339:BH719_RS05605
uniprot id: A0A1D8B2L2
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS00375
gene id: 178339:BH719_RS00375
uniprot id: A0A1D8B0A0
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

178339:BH719 RS02785
gene id: 178339:BH719_RS02785
uniprot id: A0A1D8B4C8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

178339:BH719 RS04425
gene id: 178339:BH719_RS04425
uniprot id: A0A1D8B227
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

178339:BH719 RS07325
gene id: 178339:BH719_RS07325
uniprot id: A0A1D8B3F3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

178339:BH719 RS01130
gene id: 178339:BH719_RS01130
uniprot id: A0A1D8B0I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

178339:BH719 RS02135
gene id: 178339:BH719_RS02135
uniprot id: A0A1D8B104
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

178339:BH719 RS03200
gene id: 178339:BH719_RS03200
uniprot id: A0A1D8B1H3
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS02120
gene id: 178339:BH719_RS02120
uniprot id: A0A1D8B116
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

178339:BH719 RS08765
gene id: 178339:BH719_RS08765
uniprot id: A0A1D8B439
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS03910
gene id: 178339:BH719_RS03910
uniprot id: A0A1D8B1U3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

178339:BH719 RS00170
gene id: 178339:BH719_RS00170
uniprot id: A0A1D8B039
names: Similarity
messages: Belongs to the ABC transporter superfamily.

178339:BH719 RS05610
gene id: 178339:BH719_RS05610
uniprot id: A0A1D8B2R7
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS02150
gene id: 178339:BH719_RS02150
uniprot id: A0A1D8B0Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

178339:BH719 RS04195
gene id: 178339:BH719_RS04195
uniprot id: A0A1D8B1Y6
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

178339:BH719 RS00020
gene id: 178339:BH719_RS00020
uniprot id: A0A1D8B022
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS03055
gene id: 178339:BH719_RS03055
uniprot id: A0A1D8B1F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS00165
gene id: 178339:BH719_RS00165
uniprot id: A0A1D8B033
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS01650
gene id: 178339:BH719_RS01650
uniprot id: A0A1D8B0S8
names: Similarity
messages: Belongs to the peptidase M1 family.

178339:BH719 RS04050
gene id: 178339:BH719_RS04050
uniprot id: A0A1D8B1V5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

178339:BH719 RS08450
gene id: 178339:BH719_RS08450
uniprot id: A0A1D8B405
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

178339:BH719 RS08030
gene id: 178339:BH719_RS08030
uniprot id: A0A1D8B3T4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

178339:BH719 RS00225
gene id: 178339:BH719_RS00225
uniprot id: A0A1D8B046
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

178339:BH719 RS07440
gene id: 178339:BH719_RS07440
uniprot id: A0A1D8B3I1
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS05600
gene id: 178339:BH719_RS05600
uniprot id: A0A1D8B2L4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS02325
gene id: 178339:BH719_RS02325
uniprot id: A0A1D8B151
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

178339:BH719 RS01120
gene id: 178339:BH719_RS01120
uniprot id: A0A1D8B0K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

178339:BH719 RS07340
gene id: 178339:BH719_RS07340
uniprot id: A0A1D8B3F6
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS01645
gene id: 178339:BH719_RS01645
uniprot id: A0A1D8B0R4
names: Similarity
messages: Belongs to the peptidase M13 family.

178339:BH719 RS06805
gene id: 178339:BH719_RS06805
uniprot id: A0A1D8B378
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

178339:BH719 RS00205
gene id: 178339:BH719_RS00205
uniprot id: A0A1D8B072
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

178339:BH719 RS08585
gene id: 178339:BH719_RS08585
uniprot id: A0A1D8B434
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

178339:BH719 RS04570
gene id: 178339:BH719_RS04570
uniprot id: A0A1D8B272
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

178339:BH719 RS07660
gene id: 178339:BH719_RS07660
uniprot id: A0A1D8B3K5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

178339:BH719 RS04310
gene id: 178339:BH719_RS04310
uniprot id: A0A1D8B4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

178339:BH719 RS07090
gene id: 178339:BH719_RS07090
uniprot id: A0A1D8B3B2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

178339:BH719 RS06810
gene id: 178339:BH719_RS06810
uniprot id: A0A1D8B370
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS07185
gene id: 178339:BH719_RS07185
uniprot id: A0A1D8B3E0
names: Similarity
messages: Belongs to the peptidase S33 family.

178339:BH719 RS02080
gene id: 178339:BH719_RS02080
uniprot id: A0A1D8B0Z2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS04460
gene id: 178339:BH719_RS04460
uniprot id: A0A1D8B232
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

178339:BH719 RS07590
gene id: 178339:BH719_RS07590
uniprot id: A0A1D8B3K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

178339:BH719 RS01720
gene id: 178339:BH719_RS01720
uniprot id: A0A1D8B0S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

178339:BH719 RS06165
gene id: 178339:BH719_RS06165
uniprot id: A0A1D8B2X6
names: Similarity
messages: Belongs to the peptidase S8 family.

178339:BH719 RS00580
gene id: 178339:BH719_RS00580
uniprot id: A0A1D8B0B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

178339:BH719 RS02245
gene id: 178339:BH719_RS02245
uniprot id: A0A1D8B102
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

178339:BH719 RS01860
gene id: 178339:BH719_RS01860
uniprot id: A0A1D8B0V8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

178339:BH719 RS00990
gene id: 178339:BH719_RS00990
uniprot id: A0A1D8B0F9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

178339:BH719 RS02330
gene id: 178339:BH719_RS02330
uniprot id: A0A1D8B143
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

178339:BH719 RS06400
gene id: 178339:BH719_RS06400
uniprot id: A0A1D8B309
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

178339:BH719 RS05475
gene id: 178339:BH719_RS05475
uniprot id: A0A1D8B2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

178339:BH719 RS00100
gene id: 178339:BH719_RS00100
uniprot id: A0A1D8B035
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS06750
gene id: 178339:BH719_RS06750
uniprot id: A0A1D8B364
names: Similarity
messages: Belongs to the Nudix hydrolase family.

178339:BH719 RS02705
gene id: 178339:BH719_RS02705
uniprot id: A0A1D8B196
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

178339:BH719 RS00630
gene id: 178339:BH719_RS00630
uniprot id: A0A1D8B0F2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

178339:BH719 RS04200
gene id: 178339:BH719_RS04200
uniprot id: A0A1D8B1Y3
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

178339:BH719 RS06635
gene id: 178339:BH719_RS06635
uniprot id: A0A1D8B342
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

178339:BH719 RS07670
gene id: 178339:BH719_RS07670
uniprot id: A0A1D8B3M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS02915
gene id: 178339:BH719_RS02915
uniprot id: A0A1D8B1B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

178339:BH719 RS06170
gene id: 178339:BH719_RS06170
uniprot id: A0A1D8B2X0
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS00940
gene id: 178339:BH719_RS00940
uniprot id: A0A1D8B0F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

178339:BH719 RS07200
gene id: 178339:BH719_RS07200
uniprot id: A0A1D8B3D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS04435
gene id: 178339:BH719_RS04435
uniprot id: A0A1D8B228
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

178339:BH719 RS06030
gene id: 178339:BH719_RS06030
uniprot id: A0A1D8B2V5
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

178339:BH719 RS02205
gene id: 178339:BH719_RS02205
uniprot id: A0A1D8B113
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

178339:BH719 RS06630
gene id: 178339:BH719_RS06630
uniprot id: A0A1D8B363
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

178339:BH719 RS04360
gene id: 178339:BH719_RS04360
uniprot id: A0A1D8B249
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

178339:BH719 RS01110
gene id: 178339:BH719_RS01110
uniprot id: A0A1D8B484
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

178339:BH719 RS07635
gene id: 178339:BH719_RS07635
uniprot id: A0A1D8B3K3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

178339:BH719 RS03645
gene id: 178339:BH719_RS03645
uniprot id: A0A1D8B1R0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS08575
gene id: 178339:BH719_RS08575
uniprot id: A0A1D8B417
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

178339:BH719 RS08825
gene id: 178339:BH719_RS08825
uniprot id: A0A1D8B449
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

178339:BH719 RS03195
gene id: 178339:BH719_RS03195
uniprot id: A0A1D8B1H1
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS05555
gene id: 178339:BH719_RS05555
uniprot id: A0A1D8B2P3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

178339:BH719 RS00670
gene id: 178339:BH719_RS00670
uniprot id: A0A1D8B4B1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS10170
gene id: 178339:BH719_RS10170
uniprot id: A0A1D8B3G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

178339:BH719 RS00290
gene id: 178339:BH719_RS00290
uniprot id: A0A1D8B057
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

178339:BH719 RS02195
gene id: 178339:BH719_RS02195
uniprot id: A0A1D8B132
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

178339:BH719 RS07195
gene id: 178339:BH719_RS07195
uniprot id: A0A1D8B3D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS06420
gene id: 178339:BH719_RS06420
uniprot id: A0A1D8B313
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

178339:BH719 RS03145
gene id: 178339:BH719_RS03145
uniprot id: A0A1D8B1G5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

178339:BH719 RS06305
gene id: 178339:BH719_RS06305
uniprot id: A0A1D8B308
names: Similarity
messages: Belongs to the LacAB/RpiB family.

178339:BH719 RS07105
gene id: 178339:BH719_RS07105
uniprot id: A0A1D8B3B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

178339:BH719 RS06445
gene id: 178339:BH719_RS06445
uniprot id: A0A1D8B2Z7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

178339:BH719 RS01345
gene id: 178339:BH719_RS01345
uniprot id: A0A1D8B0L4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

178339:BH719 RS02540
gene id: 178339:BH719_RS02540
uniprot id: A0A1D8B163
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS08290
gene id: 178339:BH719_RS08290
uniprot id: A0A1D8B3W3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

178339:BH719 RS01280
gene id: 178339:BH719_RS01280
uniprot id: A0A1D8B0N9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

178339:BH719 RS01105
gene id: 178339:BH719_RS01105
uniprot id: A0A1D8B0H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

178339:BH719 RS07970
gene id: 178339:BH719_RS07970
uniprot id: A0A1D8B3S3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

178339:BH719 RS06915
gene id: 178339:BH719_RS06915
uniprot id: A0A1D8B386
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

178339:BH719 RS03655
gene id: 178339:BH719_RS03655
uniprot id: A0A1D8B1Q8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

178339:BH719 RS02805
gene id: 178339:BH719_RS02805
uniprot id: A0A1D8B1A9
names: Subcellular Location Annotation
messages: chloroplast

178339:BH719 RS00620
gene id: 178339:BH719_RS00620
uniprot id: A0A1D8B0D9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

178339:BH719 RS00160
gene id: 178339:BH719_RS00160
uniprot id: A0A1D8B044
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS07630
gene id: 178339:BH719_RS07630
uniprot id: A0A1D8B3L1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

178339:BH719 RS04125
gene id: 178339:BH719_RS04125
uniprot id: A0A1D8B1Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

178339:BH719 RS08470
gene id: 178339:BH719_RS08470
uniprot id: A0A1D8B3Z3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

178339:BH719 RS07890
gene id: 178339:BH719_RS07890
uniprot id: A0A1D8B3T2
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

178339:BH719 RS04030
gene id: 178339:BH719_RS04030
uniprot id: A0A1D8B1V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

178339:BH719 RS08860
gene id: 178339:BH719_RS08860
uniprot id: A0A1D8B453
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

178339:BH719 RS04680
gene id: 178339:BH719_RS04680
uniprot id: A0A1D8B276
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

178339:BH719 RS04515
gene id: 178339:BH719_RS04515
uniprot id: A0A1D8B239
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

178339:BH719 RS00565
gene id: 178339:BH719_RS00565
uniprot id: A0A1D8B0D0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

178339:BH719 RS04135
gene id: 178339:BH719_RS04135
uniprot id: A0A1D8B4E5
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

178339:BH719 RS07110
gene id: 178339:BH719_RS07110
uniprot id: A0A1D8B3D6
names: Similarity
messages: Belongs to the UPF0749 family.

178339:BH719 RS00250
gene id: 178339:BH719_RS00250
uniprot id: A0A1D8B062
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

178339:BH719 RS05130
gene id: 178339:BH719_RS05130
uniprot id: A0A1D8B2G1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

178339:BH719 RS08415
gene id: 178339:BH719_RS08415
uniprot id: A0A1D8B3Y9
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS02775
gene id: 178339:BH719_RS02775
uniprot id: A0A1D8B197
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS00540
gene id: 178339:BH719_RS00540
uniprot id: A0A1D8B097
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

178339:BH719 RS08785
gene id: 178339:BH719_RS08785
uniprot id: A0A1D8B443
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

178339:BH719 RS07280
gene id: 178339:BH719_RS07280
uniprot id: A0A1D8B3I7
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

178339:BH719 RS00530
gene id: 178339:BH719_RS00530
uniprot id: A0A1D8B0A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

178339:BH719 RS03140
gene id: 178339:BH719_RS03140
uniprot id: A0A1D8B1G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

178339:BH719 RS00935
gene id: 178339:BH719_RS00935
uniprot id: A0A1D8B0G1
names: Similarity
messages: Belongs to the Lgt family.

178339:BH719 RS05995
gene id: 178339:BH719_RS05995
uniprot id: A0A1D8B2T9
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS05700
gene id: 178339:BH719_RS05700
uniprot id: A0A1D8B2P7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

178339:BH719 RS04280
gene id: 178339:BH719_RS04280
uniprot id: A0A1D8B1Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

178339:BH719 RS08610
gene id: 178339:BH719_RS08610
uniprot id: A0A1D8B419
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

178339:BH719 RS00195
gene id: 178339:BH719_RS00195
uniprot id: A0A1D8B060
names: Similarity
messages: Belongs to the glutamine synthetase family.

178339:BH719 RS04405
gene id: 178339:BH719_RS04405
uniprot id: A0A1D8B222
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

178339:BH719 RS00875
gene id: 178339:BH719_RS00875
uniprot id: A0A1D8B0F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

178339:BH719 RS00495
gene id: 178339:BH719_RS00495
uniprot id: A0A1D8B089
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

178339:BH719 RS00305
gene id: 178339:BH719_RS00305
uniprot id: A0A1D8B068
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

178339:BH719 RS07925
gene id: 178339:BH719_RS07925
uniprot id: A0A1D8B3R6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS01940
gene id: 178339:BH719_RS01940
uniprot id: A0A1D8B0Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

178339:BH719 RS00220
gene id: 178339:BH719_RS00220
uniprot id: A0A1D8B045
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

178339:BH719 RS01310
gene id: 178339:BH719_RS01310
uniprot id: A0A1D8B0L7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

178339:BH719 RS04295
gene id: 178339:BH719_RS04295
uniprot id: A0A1D8B214
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

178339:BH719 RS01755
gene id: 178339:BH719_RS01755
uniprot id: A0A1D8B0S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

178339:BH719 RS03745
gene id: 178339:BH719_RS03745
uniprot id: A0A1D8B1Q6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

178339:BH719 RS03040
gene id: 178339:BH719_RS03040
uniprot id: A0A1D8B1H7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

178339:BH719 RS01600
gene id: 178339:BH719_RS01600
uniprot id: A0A1D8B0U2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

178339:BH719 RS08445
gene id: 178339:BH719_RS08445
uniprot id: A0A1D8B3Z8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

178339:BH719 RS00610
gene id: 178339:BH719_RS00610
uniprot id: A0A1D8B0B9
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS01950
gene id: 178339:BH719_RS01950
uniprot id: A0A1D8B0Z8
names: Subcellular Location Annotation
messages: Cytoplasm

178339:BH719 RS00870
gene id: 178339:BH719_RS00870
uniprot id: A0A1D8B0E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

178339:BH719 RS02185
gene id: 178339:BH719_RS02185
uniprot id: A0A1D8B4C3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

178339:BH719 RS01620
gene id: 178339:BH719_RS01620
uniprot id: A0A1D8B0V5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

178339:BH719 RS05215
gene id: 178339:BH719_RS05215
uniprot id: A0A1D8B2G6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

178339:BH719 RS08770
gene id: 178339:BH719_RS08770
uniprot id: A0A1D8B447
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS05055
gene id: 178339:BH719_RS05055
uniprot id: A0A1D8B2G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

178339:BH719 RS02535
gene id: 178339:BH719_RS02535
uniprot id: A0A1D8B165
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

178339:BH719 RS08325
gene id: 178339:BH719_RS08325
uniprot id: A0A1D8B3W9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

178339:BH719 RS00825
gene id: 178339:BH719_RS00825
uniprot id: A0A1D8B0D5
names: Similarity
messages: Belongs to the YciI family.

178339:BH719 RS00650
gene id: 178339:BH719_RS00650
uniprot id: A0A1D8B0B4
names: Similarity
messages: Belongs to the UPF0749 family.

178339:BH719 RS05105
gene id: 178339:BH719_RS05105
uniprot id: A0A1D8B2E7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

178339:BH719 RS01585
gene id: 178339:BH719_RS01585
uniprot id: A0A1D8B0Q5
names: Similarity
messages: Belongs to the peptidase S8 family.

178339:BH719 RS01640
gene id: 178339:BH719_RS01640
uniprot id: A0A1D8B0S6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

178339:BH719 RS05965
gene id: 178339:BH719_RS05965
uniprot id: A0A1D8B2R3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

178339:BH719 RS03755
gene id: 178339:BH719_RS03755
uniprot id: A0A1D8B1R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS04560
gene id: 178339:BH719_RS04560
uniprot id: A0A1D8B250
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

178339:BH719 RS05440
gene id: 178339:BH719_RS05440
uniprot id: A0A1D8B2L8
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

178339:BH719 RS04130
gene id: 178339:BH719_RS04130
uniprot id: A0A1D8B1Y7
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

178339:BH719 RS08755
gene id: 178339:BH719_RS08755
uniprot id: A0A1D8B473
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

178339:BH719 RS05360
gene id: 178339:BH719_RS05360
uniprot id: A0A1D8B2J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

178339:BH719 RS04500
gene id: 178339:BH719_RS04500
uniprot id: A0A1D8B254
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

178339:BH719 RS05265
gene id: 178339:BH719_RS05265
uniprot id: A0A1D8B2I3
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

178339:BH719 RS00025
gene id: 178339:BH719_RS00025
uniprot id: A0A1D8B020
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

178339:BH719 RS01115
gene id: 178339:BH719_RS01115
uniprot id: A0A1D8B0L3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

178339:BH719 RS00665
gene id: 178339:BH719_RS00665
uniprot id: A0A1D8B0C5
names: Similarity
messages: Belongs to the peptidase M1 family.

178339:BH719 RS01135
gene id: 178339:BH719_RS01135
uniprot id: A0A1D8B0I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

178339:BH719 RS06930
gene id: 178339:BH719_RS06930
uniprot id: A0A1D8B3A8
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS02225
gene id: 178339:BH719_RS02225
uniprot id: A0A1D8B101
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

178339:BH719 RS06195
gene id: 178339:BH719_RS06195
uniprot id: A0A1D8B2V4
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS00655
gene id: 178339:BH719_RS00655
uniprot id: A0A1D8B0D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

178339:BH719 RS06830
gene id: 178339:BH719_RS06830
uniprot id: A0A1D8B379
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

178339:BH719 RS05745
gene id: 178339:BH719_RS05745
uniprot id: A0A1D8B2N3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

178339:BH719 RS01795
gene id: 178339:BH719_RS01795
uniprot id: A0A1D8B0U6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

178339:BH719 RS04565
gene id: 178339:BH719_RS04565
uniprot id: A0A1D8B260
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

178339:BH719 RS02210
gene id: 178339:BH719_RS02210
uniprot id: A0A1D8B110
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

178339:BH719 RS04975
gene id: 178339:BH719_RS04975
uniprot id: A0A1D8B2D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

178339:BH719 RS03635
gene id: 178339:BH719_RS03635
uniprot id: A0A1D8B1S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

178339:BH719 RS03650
gene id: 178339:BH719_RS03650
uniprot id: A0A1D8B1P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

178339:BH719 RS03625
gene id: 178339:BH719_RS03625
uniprot id: A0A1D8B1N5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

178339:BH719 RS08735
gene id: 178339:BH719_RS08735
uniprot id: A0A1D8B442
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

178339:BH719 RS03630
gene id: 178339:BH719_RS03630
uniprot id: A0A1D8B1P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

178339:BH719 RS00345
gene id: 178339:BH719_RS00345
uniprot id: A0A1D8B059
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

178339:BH719 RS04390
gene id: 178339:BH719_RS04390
uniprot id: A0A1D8B4H8
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

178339:BH719 RS04855
gene id: 178339:BH719_RS04855
uniprot id: A0A1D8B2B5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

178339:BH719 RS00330
gene id: 178339:BH719_RS00330
uniprot id: A0A1D8B088
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS05370
gene id: 178339:BH719_RS05370
uniprot id: A0A1D8B2K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

178339:BH719 RS03835
gene id: 178339:BH719_RS03835
uniprot id: A0A1D8B1S6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

178339:BH719 RS01250
gene id: 178339:BH719_RS01250
uniprot id: A0A1D8B0L6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

178339:BH719 RS00545
gene id: 178339:BH719_RS00545
uniprot id: A0A1D8B094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

178339:BH719 RS03565
gene id: 178339:BH719_RS03565
uniprot id: A0A1D8B1M4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

178339:BH719 RS04140
gene id: 178339:BH719_RS04140
uniprot id: A0A1D8B1Z4
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

178339:BH719 RS04590
gene id: 178339:BH719_RS04590
uniprot id: A0A1D8B258
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

178339:BH719 RS04690
gene id: 178339:BH719_RS04690
uniprot id: A0A1D8B288
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

178339:BH719 RS01070
gene id: 178339:BH719_RS01070
uniprot id: A0A1D8B0G9
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

178339:BH719 RS01020
gene id: 178339:BH719_RS01020
uniprot id: A0A1D8B0G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

178339:BH719 RS00065
gene id: 178339:BH719_RS00065
uniprot id: A0A1D8B031
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

178339:BH719 RS04370
gene id: 178339:BH719_RS04370
uniprot id: A0A1D8B225
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

178339:BH719 RS01920
gene id: 178339:BH719_RS01920
uniprot id: A0A1D8B0W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

178339:BH719 RS09865
gene id: 178339:BH719_RS09865
uniprot id: A0A1D8B406
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

178339:BH719 RS07005
gene id: 178339:BH719_RS07005
uniprot id: A0A1D8B3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS04545
gene id: 178339:BH719_RS04545
uniprot id: A0A1D8B251
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

178339:BH719 RS02295
gene id: 178339:BH719_RS02295
uniprot id: A0A1D8B4E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

178339:BH719 RS04225
gene id: 178339:BH719_RS04225
uniprot id: A0A1D8B1Z9
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

178339:BH719 RS07865
gene id: 178339:BH719_RS07865
uniprot id: A0A1D8B3Q0
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS00265
gene id: 178339:BH719_RS00265
uniprot id: A0A1D8B064
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

178339:BH719 RS05095
gene id: 178339:BH719_RS05095
uniprot id: A0A1D8B2E9
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

178339:BH719 RS03605
gene id: 178339:BH719_RS03605
uniprot id: A0A1D8B1P6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

178339:BH719 RS08295
gene id: 178339:BH719_RS08295
uniprot id: A0A1D8B3X8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

178339:BH719 RS01930
gene id: 178339:BH719_RS01930
uniprot id: A0A1D8B0W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

178339:BH719 RS00560
gene id: 178339:BH719_RS00560
uniprot id: A0A1D8B0A2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

178339:BH719 RS04475
gene id: 178339:BH719_RS04475
uniprot id: A0A1D8B235
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

178339:BH719 RS04595
gene id: 178339:BH719_RS04595
uniprot id: A0A1D8B264
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

178339:BH719 RS01430
gene id: 178339:BH719_RS01430
uniprot id: A0A1D8B0N2
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

178339:BH719 RS01100
gene id: 178339:BH719_RS01100
uniprot id: A0A1D8B0I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

178339:BH719 RS03795
gene id: 178339:BH719_RS03795
uniprot id: A0A1D8B1T1
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS07595
gene id: 178339:BH719_RS07595
uniprot id: A0A1D8B3J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

178339:BH719 RS00060
gene id: 178339:BH719_RS00060
uniprot id: A0A1D8B027
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

178339:BH719 RS04155
gene id: 178339:BH719_RS04155
uniprot id: A0A1D8B1Y2
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS05625
gene id: 178339:BH719_RS05625
uniprot id: A0A1D8B2N6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

178339:BH719 RS04495
gene id: 178339:BH719_RS04495
uniprot id: A0A1D8B237
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

178339:BH719 RS01550
gene id: 178339:BH719_RS01550
uniprot id: A0A1D8B0Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

178339:BH719 RS01530
gene id: 178339:BH719_RS01530
uniprot id: A0A1D8B0U4
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS04580
gene id: 178339:BH719_RS04580
uniprot id: A0A1D8B270
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

178339:BH719 RS06465
gene id: 178339:BH719_RS06465
uniprot id: A0A1D8B318
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

178339:BH719 RS03665
gene id: 178339:BH719_RS03665
uniprot id: A0A1D8B4E9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

178339:BH719 RS02645
gene id: 178339:BH719_RS02645
uniprot id: A0A1D8B181
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS08760
gene id: 178339:BH719_RS08760
uniprot id: A0A1D8B441
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

178339:BH719 RS05790
gene id: 178339:BH719_RS05790
uniprot id: A0A1D8B2R5
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

178339:BH719 RS04270
gene id: 178339:BH719_RS04270
uniprot id: A0A1D8B209
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS02875
gene id: 178339:BH719_RS02875
uniprot id: A0A1D8B1B9
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

178339:BH719 RS08165
gene id: 178339:BH719_RS08165
uniprot id: A0A1D8B4K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

178339:BH719 RS03360
gene id: 178339:BH719_RS03360
uniprot id: A0A1D8B1K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

178339:BH719 RS00985
gene id: 178339:BH719_RS00985
uniprot id: A0A1D8B0K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

178339:BH719 RS00490
gene id: 178339:BH719_RS00490
uniprot id: A0A1D8B083
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

178339:BH719 RS03955
gene id: 178339:BH719_RS03955
uniprot id: A0A1D8B1W1
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

178339:BH719 RS07260
gene id: 178339:BH719_RS07260
uniprot id: A0A1D8B3F7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

178339:BH719 RS07095
gene id: 178339:BH719_RS07095
uniprot id: A0A1D8B3G0
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS04465
gene id: 178339:BH719_RS04465
uniprot id: A0A1D8B234
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

178339:BH719 RS01710
gene id: 178339:BH719_RS01710
uniprot id: A0A1D8B0T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

178339:BH719 RS08745
gene id: 178339:BH719_RS08745
uniprot id: A0A1D8B436
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

178339:BH719 RS04620
gene id: 178339:BH719_RS04620
uniprot id: A0A1D8B268
names: Similarity
messages: Belongs to the fructosamine kinase family.

178339:BH719 RS07850
gene id: 178339:BH719_RS07850
uniprot id: A0A1D8B3N2
names: Similarity
messages: Belongs to the Dps family.

178339:BH719 RS00625
gene id: 178339:BH719_RS00625
uniprot id: A0A1D8B0C3
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS01225
gene id: 178339:BH719_RS01225
uniprot id: A0A1D8B0M9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

178339:BH719 RS04985
gene id: 178339:BH719_RS04985
uniprot id: A0A1D8B2C6
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS05575
gene id: 178339:BH719_RS05575
uniprot id: A0A1D8B2M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

178339:BH719 RS01975
gene id: 178339:BH719_RS01975
uniprot id: A0A1D8B0X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

178339:BH719 RS05035
gene id: 178339:BH719_RS05035
uniprot id: A0A1D8B2D8
names: Similarity
messages: Belongs to the WXG100 family.

178339:BH719 RS04170
gene id: 178339:BH719_RS04170
uniprot id: A0A1D8B1X4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

178339:BH719 RS03845
gene id: 178339:BH719_RS03845
uniprot id: A0A1D8B1T3
names: Similarity
messages: Belongs to the ribulokinase family.

178339:BH719 RS02585
gene id: 178339:BH719_RS02585
uniprot id: A0A1D8B166
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS04740
gene id: 178339:BH719_RS04740
uniprot id: A0A1D8B282
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

178339:BH719 RS01705
gene id: 178339:BH719_RS01705
uniprot id: A0A1D8B0R9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

178339:BH719 RS07720
gene id: 178339:BH719_RS07720
uniprot id: A0A1D8B3N3
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

178339:BH719 RS06740
gene id: 178339:BH719_RS06740
uniprot id: A0A1D8B355
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS08560
gene id: 178339:BH719_RS08560
uniprot id: A0A1D8B408
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS00200
gene id: 178339:BH719_RS00200
uniprot id: A0A1D8B052
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

178339:BH719 RS07165
gene id: 178339:BH719_RS07165
uniprot id: A0A1D8B3E5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

178339:BH719 RS07780
gene id: 178339:BH719_RS07780
uniprot id: A0A1D8B3M4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

178339:BH719 RS02620
gene id: 178339:BH719_RS02620
uniprot id: A0A1D8B1A0
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS05620
gene id: 178339:BH719_RS05620
uniprot id: A0A1D8B2Q2
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS07520
gene id: 178339:BH719_RS07520
uniprot id: A0A1D8B3I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

178339:BH719 RS01935
gene id: 178339:BH719_RS01935
uniprot id: A0A1D8B0V2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

178339:BH719 RS00755
gene id: 178339:BH719_RS00755
uniprot id: A0A1D8B0D6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

178339:BH719 RS06140
gene id: 178339:BH719_RS06140
uniprot id: A0A1D8B2U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS05845
gene id: 178339:BH719_RS05845
uniprot id: A0A1D8B2S2
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS00945
gene id: 178339:BH719_RS00945
uniprot id: A0A1D8B0G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

178339:BH719 RS03435
gene id: 178339:BH719_RS03435
uniprot id: A0A1D8B1L2
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS05140
gene id: 178339:BH719_RS05140
uniprot id: A0A1D8B2G5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

178339:BH719 RS04775
gene id: 178339:BH719_RS04775
uniprot id: A0A1D8B2A7
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

178339:BH719 RS01035
gene id: 178339:BH719_RS01035
uniprot id: A0A1D8B0H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

178339:BH719 RS03550
gene id: 178339:BH719_RS03550
uniprot id: A0A1D8B1N3
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS01925
gene id: 178339:BH719_RS01925
uniprot id: A0A1D8B0V3
names: Similarity
messages: Belongs to the YggT family.

178339:BH719 RS07825
gene id: 178339:BH719_RS07825
uniprot id: A0A1D8B3N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

178339:BH719 RS07500
gene id: 178339:BH719_RS07500
uniprot id: A0A1D8B3J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS08105
gene id: 178339:BH719_RS08105
uniprot id: A0A1D8B3X2
names: Similarity
messages: Belongs to the peptidase S8 family.

178339:BH719 RS00110
gene id: 178339:BH719_RS00110
uniprot id: A0A1D8B032
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

178339:BH719 RS02180
gene id: 178339:BH719_RS02180
uniprot id: A0A1D8B124
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

178339:BH719 RS05250
gene id: 178339:BH719_RS05250
uniprot id: A0A1D8B2I2
names: Similarity
messages: Belongs to the peptidase M18 family.

178339:BH719 RS08635
gene id: 178339:BH719_RS08635
uniprot id: A0A1D8B421
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

178339:BH719 RS07225
gene id: 178339:BH719_RS07225
uniprot id: A0A1D8B3F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

178339:BH719 RS00850
gene id: 178339:BH719_RS00850
uniprot id: A0A1D8B0I6
names: Similarity
messages: Belongs to the peptidase S8 family.

178339:BH719 RS02895
gene id: 178339:BH719_RS02895
uniprot id: A0A1D8B4C9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

178339:BH719 RS00400
gene id: 178339:BH719_RS00400
uniprot id: A0A1D8B078
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

178339:BH719 RS04385
gene id: 178339:BH719_RS04385
uniprot id: A0A1D8B217
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS04330
gene id: 178339:BH719_RS04330
uniprot id: A0A1D8B210
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS08260
gene id: 178339:BH719_RS08260
uniprot id: A0A1D8B3V9
names: Similarity
messages: Belongs to the peptidase S13 family.

178339:BH719 RS05255
gene id: 178339:BH719_RS05255
uniprot id: A0A1D8B2I0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

178339:BH719 RS07605
gene id: 178339:BH719_RS07605
uniprot id: A0A1D8B3L8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

178339:BH719 RS02345
gene id: 178339:BH719_RS02345
uniprot id: A0A1D8B133
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

178339:BH719 RS04355
gene id: 178339:BH719_RS04355
uniprot id: A0A1D8B215
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

178339:BH719 RS08720
gene id: 178339:BH719_RS08720
uniprot id: A0A1D8B438
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

178339:BH719 RS04530
gene id: 178339:BH719_RS04530
uniprot id: A0A1D8B259
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

178339:BH719 RS04765
gene id: 178339:BH719_RS04765
uniprot id: A0A1D8B286
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

178339:BH719 RS07685
gene id: 178339:BH719_RS07685
uniprot id: A0A1D8B3M6
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS08565
gene id: 178339:BH719_RS08565
uniprot id: A0A1D8B416
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

178339:BH719 RS04525
gene id: 178339:BH719_RS04525
uniprot id: A0A1D8B246
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

178339:BH719 RS06850
gene id: 178339:BH719_RS06850
uniprot id: A0A1D8B367
names: Subcellular Location Annotation
messages: Cytoplasm

178339:BH719 RS04980
gene id: 178339:BH719_RS04980
uniprot id: A0A1D8B2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

178339:BH719 RS02045
gene id: 178339:BH719_RS02045
uniprot id: A0A1D8B0Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

178339:BH719 RS00980
gene id: 178339:BH719_RS00980
uniprot id: A0A1D8B0I7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

178339:BH719 RS01230
gene id: 178339:BH719_RS01230
uniprot id: A0A1D8B4A8
names: Subcellular Location Annotation
messages: Membrane

178339:BH719 RS00790
gene id: 178339:BH719_RS00790
uniprot id: A0A1D8B0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

178339:BH719 RS06395
gene id: 178339:BH719_RS06395
uniprot id: A0A1D8B324
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Cytoplasm
messages: Homotetramer.

178339:BH719 RS06645
gene id: 178339:BH719_RS06645
uniprot id: A0A1D8B359
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.