1780362:CGEO RS04910
gene id: 1780362:CGEO_RS04910
uniprot id: A0A128EKT8
names: Similarity
messages: Belongs to the HypD family.

1780362:CGEO RS05265
gene id: 1780362:CGEO_RS05265
uniprot id: A0A128EIU5
names: Subcellular Location Annotation
messages: Periplasm

1780362:CGEO RS00810
gene id: 1780362:CGEO_RS00810
uniprot id: A0A128EN81
names: Similarity
messages: Belongs to the UPF0234 family.

1780362:CGEO RS06865
gene id: 1780362:CGEO_RS06865
uniprot id: A0A128ELZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1780362:CGEO RS02045
gene id: 1780362:CGEO_RS02045
uniprot id: A0A128EI51
names: Similarity
messages: Belongs to the LOG family.

1780362:CGEO RS04575
gene id: 1780362:CGEO_RS04575
uniprot id: A0A128EJ29
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1780362:CGEO RS00905
gene id: 1780362:CGEO_RS00905
uniprot id: A0A128EB06
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS07565
gene id: 1780362:CGEO_RS07565
uniprot id: A0A128EHN2
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Secreted

1780362:CGEO RS09830
gene id: 1780362:CGEO_RS09830
uniprot id: A0A128EDG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1780362:CGEO RS05240
gene id: 1780362:CGEO_RS05240
uniprot id: A0A128EPG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1780362:CGEO RS07535
gene id: 1780362:CGEO_RS07535
uniprot id: A0A128EF75
names: Subcellular Location Annotation
messages: Cytoplasm

1780362:CGEO RS01345
gene id: 1780362:CGEO_RS01345
uniprot id: A0A128ECK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS09430
gene id: 1780362:CGEO_RS09430
uniprot id: A0A128EAA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1780362:CGEO RS01020
gene id: 1780362:CGEO_RS01020
uniprot id: A0A128ED38
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1780362:CGEO RS06985
gene id: 1780362:CGEO_RS06985
uniprot id: A0A128EK24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1780362:CGEO RS07900
gene id: 1780362:CGEO_RS07900
uniprot id: A0A128EGU6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1780362:CGEO RS04440
gene id: 1780362:CGEO_RS04440
uniprot id: A0A128EJN0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1780362:CGEO RS09565
gene id: 1780362:CGEO_RS09565
uniprot id: A0A128ECB0
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS01080
gene id: 1780362:CGEO_RS01080
uniprot id: A0A128ENS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1780362:CGEO RS09420
gene id: 1780362:CGEO_RS09420
uniprot id: A0A128ECK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1780362:CGEO RS00945
gene id: 1780362:CGEO_RS00945
uniprot id: A0A128EAX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1780362:CGEO RS03850
gene id: 1780362:CGEO_RS03850
uniprot id: A0A128EEC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1780362:CGEO RS03220
gene id: 1780362:CGEO_RS03220
uniprot id: A0A128EER8
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.

1780362:CGEO RS01660
gene id: 1780362:CGEO_RS01660
uniprot id: A0A128E9Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1780362:CGEO RS08490
gene id: 1780362:CGEO_RS08490
uniprot id: A0A128EFY0
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS01185
gene id: 1780362:CGEO_RS01185
uniprot id: A0A128EMX1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1780362:CGEO RS09625
gene id: 1780362:CGEO_RS09625
uniprot id: A0A128EDM2
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS00870
gene id: 1780362:CGEO_RS00870
uniprot id: A0A128EB09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

1780362:CGEO RS00625
gene id: 1780362:CGEO_RS00625
uniprot id: A0A128EBR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1780362:CGEO RS06260
gene id: 1780362:CGEO_RS06260
uniprot id: A0A128EG98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1780362:CGEO RS09215
gene id: 1780362:CGEO_RS09215
uniprot id: A0A128EMZ7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1780362:CGEO RS00560
gene id: 1780362:CGEO_RS00560
uniprot id: A0A128EQ07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1780362:CGEO RS03970
gene id: 1780362:CGEO_RS03970
uniprot id: A0A128EKP2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1780362:CGEO RS04620
gene id: 1780362:CGEO_RS04620
uniprot id: A0A128EJM2
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1780362:CGEO RS07115
gene id: 1780362:CGEO_RS07115
uniprot id: A0A128ELV7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1780362:CGEO RS01885
gene id: 1780362:CGEO_RS01885
uniprot id: A0A128EC61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS02245
gene id: 1780362:CGEO_RS02245
uniprot id: A0A128EN12
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS00345
gene id: 1780362:CGEO_RS00345
uniprot id: A0A128EQ59
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1780362:CGEO RS00725
gene id: 1780362:CGEO_RS00725
uniprot id: A0A128ECH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS04950
gene id: 1780362:CGEO_RS04950
uniprot id: A0A128EJS4
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1780362:CGEO RS02925
gene id: 1780362:CGEO_RS02925
uniprot id: A0A128EEH3
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS05165
gene id: 1780362:CGEO_RS05165
uniprot id: A0A128EIM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane

1780362:CGEO RS06905
gene id: 1780362:CGEO_RS06905
uniprot id: A0A128ELY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS01965
gene id: 1780362:CGEO_RS01965
uniprot id: A0A128ELM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1780362:CGEO RS04880
gene id: 1780362:CGEO_RS04880
uniprot id: A0A128EKD4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1780362:CGEO RS00645
gene id: 1780362:CGEO_RS00645
uniprot id: A0A128ECN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1780362:CGEO RS00685
gene id: 1780362:CGEO_RS00685
uniprot id: A0A128EDD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1780362:CGEO RS03920
gene id: 1780362:CGEO_RS03920
uniprot id: A0A128EIS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1780362:CGEO RS06805
gene id: 1780362:CGEO_RS06805
uniprot id: A0A128EKD7
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1780362:CGEO RS02255
gene id: 1780362:CGEO_RS02255
uniprot id: A0A128EIL2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1780362:CGEO RS06915
gene id: 1780362:CGEO_RS06915
uniprot id: A0A128ESU4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1780362:CGEO RS05245
gene id: 1780362:CGEO_RS05245
uniprot id: A0A128EI56
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1780362:CGEO RS03190
gene id: 1780362:CGEO_RS03190
uniprot id: A0A128EFR3
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS03055
gene id: 1780362:CGEO_RS03055
uniprot id: A0A128EKG5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1780362:CGEO RS02115
gene id: 1780362:CGEO_RS02115
uniprot id: A0A128EEG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1780362:CGEO RS03835
gene id: 1780362:CGEO_RS03835
uniprot id: A0A128EHQ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1780362:CGEO RS00255
gene id: 1780362:CGEO_RS00255
uniprot id: A0A128ED25
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS09220
gene id: 1780362:CGEO_RS09220
uniprot id: A0A128ECS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1780362:CGEO RS00950
gene id: 1780362:CGEO_RS00950
uniprot id: A0A128ECK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1780362:CGEO RS06700
gene id: 1780362:CGEO_RS06700
uniprot id: A0A128EIK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1780362:CGEO RS00740
gene id: 1780362:CGEO_RS00740
uniprot id: A0A128EPE1
names: Cofactor
names: Function
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Binds 1 zinc ion per subunit.

1780362:CGEO RS02605
gene id: 1780362:CGEO_RS02605
uniprot id: A0A128EGC8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1780362:CGEO RS01490
gene id: 1780362:CGEO_RS01490
uniprot id: A0A128ECQ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1780362:CGEO RS02220
gene id: 1780362:CGEO_RS02220
uniprot id: A0A128ENF8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS02920
gene id: 1780362:CGEO_RS02920
uniprot id: A0A128EDD8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1780362:CGEO RS08460
gene id: 1780362:CGEO_RS08460
uniprot id: A0A128EH05
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS05710
gene id: 1780362:CGEO_RS05710
uniprot id: A0A128EHQ5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1780362:CGEO RS04690
gene id: 1780362:CGEO_RS04690
uniprot id: A0A128ESQ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1780362:CGEO RS01430
gene id: 1780362:CGEO_RS01430
uniprot id: A0A128EMD5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1780362:CGEO RS00850
gene id: 1780362:CGEO_RS00850
uniprot id: A0A128ECQ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1780362:CGEO RS04300
gene id: 1780362:CGEO_RS04300
uniprot id: A0A128EI49
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1780362:CGEO RS03385
gene id: 1780362:CGEO_RS03385
uniprot id: A0A128EN69
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS04375
gene id: 1780362:CGEO_RS04375
uniprot id: A0A128EIS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1780362:CGEO RS05275
gene id: 1780362:CGEO_RS05275
uniprot id: A0A128EI66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerH subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1780362:CGEO RS08975
gene id: 1780362:CGEO_RS08975
uniprot id: A0A128EF44
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1780362:CGEO RS01465
gene id: 1780362:CGEO_RS01465
uniprot id: A0A128ECP4
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1780362:CGEO RS08335
gene id: 1780362:CGEO_RS08335
uniprot id: A0A128EHT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1780362:CGEO RS04815
gene id: 1780362:CGEO_RS04815
uniprot id: A0A128EJH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1780362:CGEO RS04465
gene id: 1780362:CGEO_RS04465
uniprot id: A0A128EKF0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1780362:CGEO RS05820
gene id: 1780362:CGEO_RS05820
uniprot id: A0A128EG46
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1780362:CGEO RS00180
gene id: 1780362:CGEO_RS00180
uniprot id: A0A128EBR8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1780362:CGEO RS00550
gene id: 1780362:CGEO_RS00550
uniprot id: A0A128EBD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1780362:CGEO RS04265
gene id: 1780362:CGEO_RS04265
uniprot id: A0A128EMS0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1780362:CGEO RS01690
gene id: 1780362:CGEO_RS01690
uniprot id: A0A128ECD6
names: Subcellular Location Annotation
messages: Periplasm

1780362:CGEO RS09350
gene id: 1780362:CGEO_RS09350
uniprot id: A0A128ECK6
names: Similarity
messages: Belongs to the citrate synthase family.

1780362:CGEO RS01400
gene id: 1780362:CGEO_RS01400
uniprot id: A0A128EA88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1780362:CGEO RS00140
gene id: 1780362:CGEO_RS00140
uniprot id: A0A128ENM3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1780362:CGEO RS07935
gene id: 1780362:CGEO_RS07935
uniprot id: A0A128EDD3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1780362:CGEO RS08325
gene id: 1780362:CGEO_RS08325
uniprot id: A0A128EHR0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1780362:CGEO RS02380
gene id: 1780362:CGEO_RS02380
uniprot id: A0A128ENI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1780362:CGEO RS02090
gene id: 1780362:CGEO_RS02090
uniprot id: A0A128EED3
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS01865
gene id: 1780362:CGEO_RS01865
uniprot id: A0A128ED99
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1780362:CGEO RS00100
gene id: 1780362:CGEO_RS00100
uniprot id: A0A128EPU8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS06960
gene id: 1780362:CGEO_RS06960
uniprot id: A0A128EK77
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS06790
gene id: 1780362:CGEO_RS06790
uniprot id: A0A128EIG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1780362:CGEO RS08710
gene id: 1780362:CGEO_RS08710
uniprot id: A0A128EJ66
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1780362:CGEO RS08445
gene id: 1780362:CGEO_RS08445
uniprot id: A0A128EHX1
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS09000
gene id: 1780362:CGEO_RS09000
uniprot id: A0A128EF34
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS02635
gene id: 1780362:CGEO_RS02635
uniprot id: A0A128EGK8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1780362:CGEO RS09115
gene id: 1780362:CGEO_RS09115
uniprot id: A0A128EEE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

1780362:CGEO RS01030
gene id: 1780362:CGEO_RS01030
uniprot id: A0A128EC28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1780362:CGEO RS02435
gene id: 1780362:CGEO_RS02435
uniprot id: A0A128EPF6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1780362:CGEO RS01665
gene id: 1780362:CGEO_RS01665
uniprot id: A0A128EA12
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1780362:CGEO RS01590
gene id: 1780362:CGEO_RS01590
uniprot id: A0A128ECH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1780362:CGEO RS04790
gene id: 1780362:CGEO_RS04790
uniprot id: A0A128EIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS01005
gene id: 1780362:CGEO_RS01005
uniprot id: A0A128EAU1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1780362:CGEO RS00360
gene id: 1780362:CGEO_RS00360
uniprot id: A0A128EBL2
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1780362:CGEO RS05195
gene id: 1780362:CGEO_RS05195
uniprot id: A0A128EIZ1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1780362:CGEO RS05775
gene id: 1780362:CGEO_RS05775
uniprot id: A0A128EJC2
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1780362:CGEO RS09600
gene id: 1780362:CGEO_RS09600
uniprot id: A0A128EM12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1780362:CGEO RS01640
gene id: 1780362:CGEO_RS01640
uniprot id: A0A128EE66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1780362:CGEO RS06255
gene id: 1780362:CGEO_RS06255
uniprot id: A0A128EPY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1780362:CGEO RS08330
gene id: 1780362:CGEO_RS08330
uniprot id: A0A128EPS5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1780362:CGEO RS06690
gene id: 1780362:CGEO_RS06690
uniprot id: A0A128EJK2
names: Subcellular Location Annotation
messages: Periplasm

1780362:CGEO RS04855
gene id: 1780362:CGEO_RS04855
uniprot id: A0A128EPT2
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1780362:CGEO RS08115
gene id: 1780362:CGEO_RS08115
uniprot id: A0A128EQU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

1780362:CGEO RS04495
gene id: 1780362:CGEO_RS04495
uniprot id: A0A128EJU8
names: Similarity
messages: Belongs to the AAA ATPase family.

1780362:CGEO RS04060
gene id: 1780362:CGEO_RS04060
uniprot id: A0A128EL24
names: Subcellular Location Annotation
messages: Mitochondrion

1780362:CGEO RS08225
gene id: 1780362:CGEO_RS08225
uniprot id: A0A128EPE9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1780362:CGEO RS02860
gene id: 1780362:CGEO_RS02860
uniprot id: A0A128EKX9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1780362:CGEO RS08305
gene id: 1780362:CGEO_RS08305
uniprot id: A0A128EG93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1780362:CGEO RS01475
gene id: 1780362:CGEO_RS01475
uniprot id: A0A128EAD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1780362:CGEO RS08180
gene id: 1780362:CGEO_RS08180
uniprot id: A0A128EGE9
names: Similarity
messages: Belongs to the GSP E family.

1780362:CGEO RS08070
gene id: 1780362:CGEO_RS08070
uniprot id: A0A128EEN5
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS01285
gene id: 1780362:CGEO_RS01285
uniprot id: A0A128EBY5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS07120
gene id: 1780362:CGEO_RS07120
uniprot id: A0A128EKC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1780362:CGEO RS01035
gene id: 1780362:CGEO_RS01035
uniprot id: A0A128ECY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1780362:CGEO RS01205
gene id: 1780362:CGEO_RS01205
uniprot id: A0A128ECF8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS05745
gene id: 1780362:CGEO_RS05745
uniprot id: A0A128EHT9
names: Similarity
messages: Belongs to the TrpC family.

1780362:CGEO RS03210
gene id: 1780362:CGEO_RS03210
uniprot id: A0A128ENH4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1780362:CGEO RS09195
gene id: 1780362:CGEO_RS09195
uniprot id: A0A128EBJ8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1780362:CGEO RS02385
gene id: 1780362:CGEO_RS02385
uniprot id: A0A128EGP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1780362:CGEO RS05880
gene id: 1780362:CGEO_RS05880
uniprot id: A0A128EP67
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1780362:CGEO RS04050
gene id: 1780362:CGEO_RS04050
uniprot id: A0A128EHD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1780362:CGEO RS05175
gene id: 1780362:CGEO_RS05175
uniprot id: A0A128EH95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1780362:CGEO RS05035
gene id: 1780362:CGEO_RS05035
uniprot id: A0A128EGX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1780362:CGEO RS09340
gene id: 1780362:CGEO_RS09340
uniprot id: A0A128ECF1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1780362:CGEO RS09720
gene id: 1780362:CGEO_RS09720
uniprot id: A0A128EEC7
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1780362:CGEO RS09780
gene id: 1780362:CGEO_RS09780
uniprot id: A0A128EMP1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1780362:CGEO RS03005
gene id: 1780362:CGEO_RS03005
uniprot id: A0A128EDC6
names: Similarity
messages: Belongs to the peptidase M16 family.

1780362:CGEO RS02210
gene id: 1780362:CGEO_RS02210
uniprot id: A0A128EJQ3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1780362:CGEO RS06900
gene id: 1780362:CGEO_RS06900
uniprot id: A0A128ER40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1780362:CGEO RS09440
gene id: 1780362:CGEO_RS09440
uniprot id: A0A128EDV4
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

1780362:CGEO RS03030
gene id: 1780362:CGEO_RS03030
uniprot id: A0A128ELE8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1780362:CGEO RS07950
gene id: 1780362:CGEO_RS07950
uniprot id: A0A128EES9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS09335
gene id: 1780362:CGEO_RS09335
uniprot id: A0A128EE72
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1780362:CGEO RS07575
gene id: 1780362:CGEO_RS07575
uniprot id: A0A128EHW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1780362:CGEO RS02360
gene id: 1780362:CGEO_RS02360
uniprot id: A0A128EEL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1780362:CGEO RS09380
gene id: 1780362:CGEO_RS09380
uniprot id: A0A128ECJ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Membrane

1780362:CGEO RS05190
gene id: 1780362:CGEO_RS05190
uniprot id: A0A128EI31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1780362:CGEO RS08470
gene id: 1780362:CGEO_RS08470
uniprot id: A0A128EG36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1780362:CGEO RS05705
gene id: 1780362:CGEO_RS05705
uniprot id: A0A128ENZ9
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1780362:CGEO RS08245
gene id: 1780362:CGEO_RS08245
uniprot id: A0A128EEJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.

1780362:CGEO RS02290
gene id: 1780362:CGEO_RS02290
uniprot id: A0A128EJY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane

1780362:CGEO RS09785
gene id: 1780362:CGEO_RS09785
uniprot id: A0A128EAT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1780362:CGEO RS03280
gene id: 1780362:CGEO_RS03280
uniprot id: A0A128EGZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1780362:CGEO RS08210
gene id: 1780362:CGEO_RS08210
uniprot id: A0A128EEH6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS03520
gene id: 1780362:CGEO_RS03520
uniprot id: A0A128EFH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatB family.
messages: Cell membrane

1780362:CGEO RS09310
gene id: 1780362:CGEO_RS09310
uniprot id: A0A128ECM3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS00675
gene id: 1780362:CGEO_RS00675
uniprot id: A0A128ECJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1780362:CGEO RS07550
gene id: 1780362:CGEO_RS07550
uniprot id: A0A128EGZ9
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Periplasm

1780362:CGEO RS00370
gene id: 1780362:CGEO_RS00370
uniprot id: A0A128EBE5
names: Similarity
messages: Belongs to the RecJ family.

1780362:CGEO RS01180
gene id: 1780362:CGEO_RS01180
uniprot id: A0A128EAI8
names: Similarity
messages: Belongs to the thioredoxin family.

1780362:CGEO RS04615
gene id: 1780362:CGEO_RS04615
uniprot id: A0A128EL37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1780362:CGEO RS01825
gene id: 1780362:CGEO_RS01825
uniprot id: A0A128EMC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1780362:CGEO RS06170
gene id: 1780362:CGEO_RS06170
uniprot id: A0A128EJB9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1780362:CGEO RS00890
gene id: 1780362:CGEO_RS00890
uniprot id: A0A128EN57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1780362:CGEO RS04665
gene id: 1780362:CGEO_RS04665
uniprot id: A0A128ESH9
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS08625
gene id: 1780362:CGEO_RS08625
uniprot id: A0A128EFU5
names: Similarity
messages: Belongs to the UPF0751 family.

1780362:CGEO RS00045
gene id: 1780362:CGEO_RS00045
uniprot id: A0A128EBW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1780362:CGEO RS09025
gene id: 1780362:CGEO_RS09025
uniprot id: A0A128E9V5
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS03345
gene id: 1780362:CGEO_RS03345
uniprot id: A0A128EFX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1780362:CGEO RS05090
gene id: 1780362:CGEO_RS05090
uniprot id: A0A128EPM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1780362:CGEO RS02940
gene id: 1780362:CGEO_RS02940
uniprot id: A0A128ELC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1780362:CGEO RS02440
gene id: 1780362:CGEO_RS02440
uniprot id: A0A128EFS4
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1780362:CGEO RS09875
gene id: 1780362:CGEO_RS09875
uniprot id: A0A128ECC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1780362:CGEO RS08810
gene id: 1780362:CGEO_RS08810
uniprot id: A0A128EFN6
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS10010
gene id: 1780362:CGEO_RS10010
uniprot id: A0A128EB26
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1780362:CGEO RS03990
gene id: 1780362:CGEO_RS03990
uniprot id: A0A128EIV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1780362:CGEO RS05715
gene id: 1780362:CGEO_RS05715
uniprot id: A0A128EQW7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

1780362:CGEO RS04660
gene id: 1780362:CGEO_RS04660
uniprot id: A0A128EJR7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1780362:CGEO RS02740
gene id: 1780362:CGEO_RS02740
uniprot id: A0A128EI20
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1780362:CGEO RS04260
gene id: 1780362:CGEO_RS04260
uniprot id: A0A128EIB0
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1780362:CGEO RS02485
gene id: 1780362:CGEO_RS02485
uniprot id: A0A128EG88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1780362:CGEO RS10005
gene id: 1780362:CGEO_RS10005
uniprot id: A0A128EBY4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS04920
gene id: 1780362:CGEO_RS04920
uniprot id: A0A128EIN1
names: Similarity
messages: Belongs to the HypE family.

1780362:CGEO RS04130
gene id: 1780362:CGEO_RS04130
uniprot id: A0A128EHB2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1780362:CGEO RS04285
gene id: 1780362:CGEO_RS04285
uniprot id: A0A128EI97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1780362:CGEO RS08655
gene id: 1780362:CGEO_RS08655
uniprot id: A0A128EHP0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1780362:CGEO RS01870
gene id: 1780362:CGEO_RS01870
uniprot id: A0A128E9Y4
names: Similarity
messages: Belongs to the fabD family.

1780362:CGEO RS07905
gene id: 1780362:CGEO_RS07905
uniprot id: A0A128EQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1780362:CGEO RS06400
gene id: 1780362:CGEO_RS06400
uniprot id: A0A128EJQ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS07450
gene id: 1780362:CGEO_RS07450
uniprot id: A0A128EH72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1780362:CGEO RS05770
gene id: 1780362:CGEO_RS05770
uniprot id: A0A128EHN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1780362:CGEO RS00010
gene id: 1780362:CGEO_RS00010
uniprot id: A0A128EBX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1780362:CGEO RS01540
gene id: 1780362:CGEO_RS01540
uniprot id: A0A128ECJ6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1780362:CGEO RS02160
gene id: 1780362:CGEO_RS02160
uniprot id: A0A128EPJ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS08035
gene id: 1780362:CGEO_RS08035
uniprot id: A0A128EEQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1780362:CGEO RS05025
gene id: 1780362:CGEO_RS05025
uniprot id: A0A128EGR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1780362:CGEO RS08365
gene id: 1780362:CGEO_RS08365
uniprot id: A0A128EHS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS00575
gene id: 1780362:CGEO_RS00575
uniprot id: A0A128ECZ8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

1780362:CGEO RS05365
gene id: 1780362:CGEO_RS05365
uniprot id: A0A128EL15
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1780362:CGEO RS01010
gene id: 1780362:CGEO_RS01010
uniprot id: A0A128ECZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1780362:CGEO RS01835
gene id: 1780362:CGEO_RS01835
uniprot id: A0A128EEC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1780362:CGEO RS05830
gene id: 1780362:CGEO_RS05830
uniprot id: A0A128EIX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1780362:CGEO RS08190
gene id: 1780362:CGEO_RS08190
uniprot id: A0A128EQK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

1780362:CGEO RS03145
gene id: 1780362:CGEO_RS03145
uniprot id: A0A128EDI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1780362:CGEO RS05640
gene id: 1780362:CGEO_RS05640
uniprot id: A0A128EFS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1780362:CGEO RS05470
gene id: 1780362:CGEO_RS05470
uniprot id: A0A128EHR6
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS06950
gene id: 1780362:CGEO_RS06950
uniprot id: A0A128ELN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1780362:CGEO RS04005
gene id: 1780362:CGEO_RS04005
uniprot id: A0A128EKJ6
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS05335
gene id: 1780362:CGEO_RS05335
uniprot id: A0A128EL26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1780362:CGEO RS03570
gene id: 1780362:CGEO_RS03570
uniprot id: A0A128EE48
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS02850
gene id: 1780362:CGEO_RS02850
uniprot id: A0A128EGE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1780362:CGEO RS08615
gene id: 1780362:CGEO_RS08615
uniprot id: A0A128EFT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1780362:CGEO RS02895
gene id: 1780362:CGEO_RS02895
uniprot id: A0A128EHV7
names: Similarity
messages: Belongs to the universal stress protein A family.

1780362:CGEO RS05075
gene id: 1780362:CGEO_RS05075
uniprot id: A0A128EIN0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1780362:CGEO RS05785
gene id: 1780362:CGEO_RS05785
uniprot id: A0A128EH03
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS01915
gene id: 1780362:CGEO_RS01915
uniprot id: A0A128ENB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1780362:CGEO RS03635
gene id: 1780362:CGEO_RS03635
uniprot id: A0A128EM42
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS09465
gene id: 1780362:CGEO_RS09465
uniprot id: A0A128EBW5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1780362:CGEO RS03305
gene id: 1780362:CGEO_RS03305
uniprot id: A0A128EDR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1780362:CGEO RS01815
gene id: 1780362:CGEO_RS01815
uniprot id: A0A128EML9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1780362:CGEO RS09810
gene id: 1780362:CGEO_RS09810
uniprot id: A0A128EAX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1780362:CGEO RS09820
gene id: 1780362:CGEO_RS09820
uniprot id: A0A128ED58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1780362:CGEO RS08150
gene id: 1780362:CGEO_RS08150
uniprot id: A0A128EPH2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1780362:CGEO RS00235
gene id: 1780362:CGEO_RS00235
uniprot id: A0A128EBS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1780362:CGEO RS02275
gene id: 1780362:CGEO_RS02275
uniprot id: A0A128EGH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1780362:CGEO RS04580
gene id: 1780362:CGEO_RS04580
uniprot id: A0A128EJD5
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS01735
gene id: 1780362:CGEO_RS01735
uniprot id: A0A128EA10
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS07305
gene id: 1780362:CGEO_RS07305
uniprot id: A0A128EGD2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1780362:CGEO RS06490
gene id: 1780362:CGEO_RS06490
uniprot id: A0A128EJK3
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS09725
gene id: 1780362:CGEO_RS09725
uniprot id: A0A128EAR8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1780362:CGEO RS01120
gene id: 1780362:CGEO_RS01120
uniprot id: A0A128ECZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS05605
gene id: 1780362:CGEO_RS05605
uniprot id: A0A128EP76
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1780362:CGEO RS01000
gene id: 1780362:CGEO_RS01000
uniprot id: A0A128ECJ8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1780362:CGEO RS00640
gene id: 1780362:CGEO_RS00640
uniprot id: A0A128EBS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1780362:CGEO RS07060
gene id: 1780362:CGEO_RS07060
uniprot id: A0A128EK09
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1780362:CGEO RS00250
gene id: 1780362:CGEO_RS00250
uniprot id: A0A128EDV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1780362:CGEO RS02470
gene id: 1780362:CGEO_RS02470
uniprot id: A0A128EER1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1780362:CGEO RS06280
gene id: 1780362:CGEO_RS06280
uniprot id: A0A128EJB1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1780362:CGEO RS01270
gene id: 1780362:CGEO_RS01270
uniprot id: A0A128ECD0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1780362:CGEO RS03325
gene id: 1780362:CGEO_RS03325
uniprot id: A0A128EFW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1780362:CGEO RS01460
gene id: 1780362:CGEO_RS01460
uniprot id: A0A128EEV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1780362:CGEO RS06310
gene id: 1780362:CGEO_RS06310
uniprot id: A0A128EJM6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1780362:CGEO RS03550
gene id: 1780362:CGEO_RS03550
uniprot id: A0A128EE27
names: Similarity
messages: Belongs to the aspartokinase family.

1780362:CGEO RS00680
gene id: 1780362:CGEO_RS00680
uniprot id: A0A128EE02
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS07645
gene id: 1780362:CGEO_RS07645
uniprot id: A0A128EF41
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS00700
gene id: 1780362:CGEO_RS00700
uniprot id: A0A128EDC2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1780362:CGEO RS02410
gene id: 1780362:CGEO_RS02410
uniprot id: A0A128EEN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1780362:CGEO RS09990
gene id: 1780362:CGEO_RS09990
uniprot id: A0A128EBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

1780362:CGEO RS02145
gene id: 1780362:CGEO_RS02145
uniprot id: A0A128EJT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

1780362:CGEO RS07290
gene id: 1780362:CGEO_RS07290
uniprot id: A0A128EHD7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1780362:CGEO RS05410
gene id: 1780362:CGEO_RS05410
uniprot id: A0A128EGZ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1780362:CGEO RS05680
gene id: 1780362:CGEO_RS05680
uniprot id: A0A128EPE5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1780362:CGEO RS05810
gene id: 1780362:CGEO_RS05810
uniprot id: A0A128EH89
names: Similarity
messages: Belongs to the UbiD family.

1780362:CGEO RS00355
gene id: 1780362:CGEO_RS00355
uniprot id: A0A128EBH5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1780362:CGEO RS02065
gene id: 1780362:CGEO_RS02065
uniprot id: A0A128EHY2
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1780362:CGEO RS07965
gene id: 1780362:CGEO_RS07965
uniprot id: A0A128EEU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1780362:CGEO RS04380
gene id: 1780362:CGEO_RS04380
uniprot id: A0A128EJK7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS07785
gene id: 1780362:CGEO_RS07785
uniprot id: A0A128EF08
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1780362:CGEO RS00540
gene id: 1780362:CGEO_RS00540
uniprot id: A0A128EBC3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1780362:CGEO RS04655
gene id: 1780362:CGEO_RS04655
uniprot id: A0A128EK47
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1780362:CGEO RS09415
gene id: 1780362:CGEO_RS09415
uniprot id: A0A128EE51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1780362:CGEO RS04915
gene id: 1780362:CGEO_RS04915
uniprot id: A0A128EJE8
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS03390
gene id: 1780362:CGEO_RS03390
uniprot id: A0A128EMH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1780362:CGEO RS02060
gene id: 1780362:CGEO_RS02060
uniprot id: A0A128EJR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1780362:CGEO RS09740
gene id: 1780362:CGEO_RS09740
uniprot id: A0A128EC37
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS07160
gene id: 1780362:CGEO_RS07160
uniprot id: A0A128ELI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1780362:CGEO RS00955
gene id: 1780362:CGEO_RS00955
uniprot id: A0A128EAV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1780362:CGEO RS03585
gene id: 1780362:CGEO_RS03585
uniprot id: A0A128EFH3
names: Similarity
messages: Belongs to the ribF family.

1780362:CGEO RS01980
gene id: 1780362:CGEO_RS01980
uniprot id: A0A128EE78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1780362:CGEO RS08075
gene id: 1780362:CGEO_RS08075
uniprot id: A0A128EF46
names: Similarity
messages: Belongs to the protease inhibitor I11 (ecotin) family.

1780362:CGEO RS04325
gene id: 1780362:CGEO_RS04325
uniprot id: A0A128EHR7
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1780362:CGEO RS01415
gene id: 1780362:CGEO_RS01415
uniprot id: A0A128EP13
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1780362:CGEO RS05690
gene id: 1780362:CGEO_RS05690
uniprot id: A0A128EJF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1780362:CGEO RS01645
gene id: 1780362:CGEO_RS01645
uniprot id: A0A128EBT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1780362:CGEO RS09800
gene id: 1780362:CGEO_RS09800
uniprot id: A0A128EDR0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1780362:CGEO RS09880
gene id: 1780362:CGEO_RS09880
uniprot id: A0A128EBZ1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1780362:CGEO RS00520
gene id: 1780362:CGEO_RS00520
uniprot id: A0A128ECU8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1780362:CGEO RS02135
gene id: 1780362:CGEO_RS02135
uniprot id: A0A128EI71
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1780362:CGEO RS01275
gene id: 1780362:CGEO_RS01275
uniprot id: A0A128EMV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1780362:CGEO RS03285
gene id: 1780362:CGEO_RS03285
uniprot id: A0A128EGM1
names: Similarity
messages: Belongs to the AdoMet synthase family.

1780362:CGEO RS03480
gene id: 1780362:CGEO_RS03480
uniprot id: A0A128EDZ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS01895
gene id: 1780362:CGEO_RS01895
uniprot id: A0A128EB83
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1780362:CGEO RS06755
gene id: 1780362:CGEO_RS06755
uniprot id: A0A128EIT8
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS00340
gene id: 1780362:CGEO_RS00340
uniprot id: A0A128EBD4
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS04695
gene id: 1780362:CGEO_RS04695
uniprot id: A0A128EQY7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1780362:CGEO RS06240
gene id: 1780362:CGEO_RS06240
uniprot id: A0A128EG85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1780362:CGEO RS04925
gene id: 1780362:CGEO_RS04925
uniprot id: A0A128EJT4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1780362:CGEO RS01500
gene id: 1780362:CGEO_RS01500
uniprot id: A0A128EA79
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS02715
gene id: 1780362:CGEO_RS02715
uniprot id: A0A128EI34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS01605
gene id: 1780362:CGEO_RS01605
uniprot id: A0A128E9Z8
names: Similarity
messages: Belongs to the TrpF family.

1780362:CGEO RS09765
gene id: 1780362:CGEO_RS09765
uniprot id: A0A128ECI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1780362:CGEO RS06705
gene id: 1780362:CGEO_RS06705
uniprot id: A0A128EQ97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1780362:CGEO RS09280
gene id: 1780362:CGEO_RS09280
uniprot id: A0A128EA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1780362:CGEO RS09805
gene id: 1780362:CGEO_RS09805
uniprot id: A0A128EMB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1780362:CGEO RS07320
gene id: 1780362:CGEO_RS07320
uniprot id: A0A128EIY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1780362:CGEO RS02800
gene id: 1780362:CGEO_RS02800
uniprot id: A0A128EIR9
names: Similarity
messages: Belongs to the pyruvate kinase family.

1780362:CGEO RS05840
gene id: 1780362:CGEO_RS05840
uniprot id: A0A128EH80
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1780362:CGEO RS04860
gene id: 1780362:CGEO_RS04860
uniprot id: A0A128EJA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1780362:CGEO RS08135
gene id: 1780362:CGEO_RS08135
uniprot id: A0A128EDP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1780362:CGEO RS08200
gene id: 1780362:CGEO_RS08200
uniprot id: A0A128EPI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1780362:CGEO RS01420
gene id: 1780362:CGEO_RS01420
uniprot id: A0A128EAB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1780362:CGEO RS02935
gene id: 1780362:CGEO_RS02935
uniprot id: A0A128ED93
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS07025
gene id: 1780362:CGEO_RS07025
uniprot id: A0A128EKA6
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS08530
gene id: 1780362:CGEO_RS08530
uniprot id: A0A128EHI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Membrane

1780362:CGEO RS05005
gene id: 1780362:CGEO_RS05005
uniprot id: A0A128EGN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS00095
gene id: 1780362:CGEO_RS00095
uniprot id: A0A128ECK0
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS03420
gene id: 1780362:CGEO_RS03420
uniprot id: A0A128EDV9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1780362:CGEO RS07915
gene id: 1780362:CGEO_RS07915
uniprot id: A0A128EEJ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS01530
gene id: 1780362:CGEO_RS01530
uniprot id: A0A128EBM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1780362:CGEO RS08285
gene id: 1780362:CGEO_RS08285
uniprot id: A0A128EQJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1780362:CGEO RS06775
gene id: 1780362:CGEO_RS06775
uniprot id: A0A128EI86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1780362:CGEO RS00120
gene id: 1780362:CGEO_RS00120
uniprot id: A0A128EQ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1780362:CGEO RS09835
gene id: 1780362:CGEO_RS09835
uniprot id: A0A128EM26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1780362:CGEO RS01615
gene id: 1780362:CGEO_RS01615
uniprot id: A0A128ECU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS05675
gene id: 1780362:CGEO_RS05675
uniprot id: A0A128EHG2
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1780362:CGEO RS01995
gene id: 1780362:CGEO_RS01995
uniprot id: A0A128ELB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1780362:CGEO RS09470
gene id: 1780362:CGEO_RS09470
uniprot id: A0A128EKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1780362:CGEO RS00450
gene id: 1780362:CGEO_RS00450
uniprot id: A0A128EBH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1780362:CGEO RS05425
gene id: 1780362:CGEO_RS05425
uniprot id: A0A128EGY0
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1780362:CGEO RS08100
gene id: 1780362:CGEO_RS08100
uniprot id: A0A128EET3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1780362:CGEO RS05945
gene id: 1780362:CGEO_RS05945
uniprot id: A0A128EKB4
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS02890
gene id: 1780362:CGEO_RS02890
uniprot id: A0A128EQR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1780362:CGEO RS06185
gene id: 1780362:CGEO_RS06185
uniprot id: A0A128EHW4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1780362:CGEO RS02515
gene id: 1780362:CGEO_RS02515
uniprot id: A0A128EGN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1780362:CGEO RS00715
gene id: 1780362:CGEO_RS00715
uniprot id: A0A128EPQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1780362:CGEO RS04470
gene id: 1780362:CGEO_RS04470
uniprot id: A0A128EIX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1780362:CGEO RS03430
gene id: 1780362:CGEO_RS03430
uniprot id: A0A128EDY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1780362:CGEO RS08420
gene id: 1780362:CGEO_RS08420
uniprot id: A0A128EG55
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS03205
gene id: 1780362:CGEO_RS03205
uniprot id: A0A128EDN5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1780362:CGEO RS09760
gene id: 1780362:CGEO_RS09760
uniprot id: A0A128EDF0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1780362:CGEO RS05685
gene id: 1780362:CGEO_RS05685
uniprot id: A0A128EHL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1780362:CGEO RS07170
gene id: 1780362:CGEO_RS07170
uniprot id: A0A128ERM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1780362:CGEO RS04700
gene id: 1780362:CGEO_RS04700
uniprot id: A0A128ELD7
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

1780362:CGEO RS08770
gene id: 1780362:CGEO_RS08770
uniprot id: A0A128EFN7
names: Similarity
messages: Belongs to the MlaA family.

1780362:CGEO RS08945
gene id: 1780362:CGEO_RS08945
uniprot id: A0A128E9Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1780362:CGEO RS05280
gene id: 1780362:CGEO_RS05280
uniprot id: A0A128EHF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1780362:CGEO RS01265
gene id: 1780362:CGEO_RS01265
uniprot id: A0A128EAM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1780362:CGEO RS01675
gene id: 1780362:CGEO_RS01675
uniprot id: A0A128EA56
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1780362:CGEO RS09840
gene id: 1780362:CGEO_RS09840
uniprot id: A0A128ED03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1780362:CGEO RS07085
gene id: 1780362:CGEO_RS07085
uniprot id: A0A128EJY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1780362:CGEO RS08780
gene id: 1780362:CGEO_RS08780
uniprot id: A0A128EGL8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1780362:CGEO RS01070
gene id: 1780362:CGEO_RS01070
uniprot id: A0A128EN00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1780362:CGEO RS06375
gene id: 1780362:CGEO_RS06375
uniprot id: A0A128EJG7
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS05585
gene id: 1780362:CGEO_RS05585
uniprot id: A0A128EFQ9
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS07985
gene id: 1780362:CGEO_RS07985
uniprot id: A0A128EFU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1780362:CGEO RS02980
gene id: 1780362:CGEO_RS02980
uniprot id: A0A128EJX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1780362:CGEO RS00080
gene id: 1780362:CGEO_RS00080
uniprot id: A0A128EBS5
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS06435
gene id: 1780362:CGEO_RS06435
uniprot id: A0A128ERQ2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1780362:CGEO RS01065
gene id: 1780362:CGEO_RS01065
uniprot id: A0A128ECA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1780362:CGEO RS01015
gene id: 1780362:CGEO_RS01015
uniprot id: A0A128EC54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1780362:CGEO RS07195
gene id: 1780362:CGEO_RS07195
uniprot id: A0A128ELI0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS01805
gene id: 1780362:CGEO_RS01805
uniprot id: A0A128ENV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1780362:CGEO RS08175
gene id: 1780362:CGEO_RS08175
uniprot id: A0A128EEJ8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1780362:CGEO RS06730
gene id: 1780362:CGEO_RS06730
uniprot id: A0A128EKH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1780362:CGEO RS09390
gene id: 1780362:CGEO_RS09390
uniprot id: A0A128EM77
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1780362:CGEO RS01795
gene id: 1780362:CGEO_RS01795
uniprot id: A0A128ED76
names: Similarity
messages: Belongs to the ParB family.

1780362:CGEO RS04895
gene id: 1780362:CGEO_RS04895
uniprot id: A0A128EIH0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1780362:CGEO RS08660
gene id: 1780362:CGEO_RS08660
uniprot id: A0A128EFX3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1780362:CGEO RS08895
gene id: 1780362:CGEO_RS08895
uniprot id: A0A128ELK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1780362:CGEO RS00375
gene id: 1780362:CGEO_RS00375
uniprot id: A0A128EBJ9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS08875
gene id: 1780362:CGEO_RS08875
uniprot id: A0A128EF90
names: Similarity
messages: Belongs to the class-I fumarase family.

1780362:CGEO RS09045
gene id: 1780362:CGEO_RS09045
uniprot id: A0A128ED54
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1780362:CGEO RS03065
gene id: 1780362:CGEO_RS03065
uniprot id: A0A128EJM4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1780362:CGEO RS03705
gene id: 1780362:CGEO_RS03705
uniprot id: A0A128EE47
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS00555
gene id: 1780362:CGEO_RS00555
uniprot id: A0A128ED01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1780362:CGEO RS04450
gene id: 1780362:CGEO_RS04450
uniprot id: A0A128EJV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS08775
gene id: 1780362:CGEO_RS08775
uniprot id: A0A128EHI9
names: Similarity
messages: Belongs to the asparaginase 1 family.

1780362:CGEO RS03905
gene id: 1780362:CGEO_RS03905
uniprot id: A0A128EHJ0
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS07100
gene id: 1780362:CGEO_RS07100
uniprot id: A0A128ELK6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1780362:CGEO RS03070
gene id: 1780362:CGEO_RS03070
uniprot id: A0A128EKZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1780362:CGEO RS02765
gene id: 1780362:CGEO_RS02765
uniprot id: A0A128EI10
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS03580
gene id: 1780362:CGEO_RS03580
uniprot id: A0A128EFH9
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

1780362:CGEO RS00230
gene id: 1780362:CGEO_RS00230
uniprot id: A0A128ED36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS03195
gene id: 1780362:CGEO_RS03195
uniprot id: A0A128EM29
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1780362:CGEO RS05940
gene id: 1780362:CGEO_RS05940
uniprot id: A0A128EK89
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1780362:CGEO RS02075
gene id: 1780362:CGEO_RS02075
uniprot id: A0A128EGD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1780362:CGEO RS05160
gene id: 1780362:CGEO_RS05160
uniprot id: A0A128EPU9
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS06005
gene id: 1780362:CGEO_RS06005
uniprot id: A0A128EK89
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1780362:CGEO RS04745
gene id: 1780362:CGEO_RS04745
uniprot id: A0A128EJU5
names: Similarity
messages: Belongs to the GSP E family.

1780362:CGEO RS03645
gene id: 1780362:CGEO_RS03645
uniprot id: A0A128EN23
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS09020
gene id: 1780362:CGEO_RS09020
uniprot id: A0A128EL79
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1780362:CGEO RS00940
gene id: 1780362:CGEO_RS00940
uniprot id: A0A128ECA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1780362:CGEO RS07760
gene id: 1780362:CGEO_RS07760
uniprot id: A0A128ELD2
names: Similarity
messages: Belongs to the RutC family.

1780362:CGEO RS01555
gene id: 1780362:CGEO_RS01555
uniprot id: A0A128EMV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1780362:CGEO RS00160
gene id: 1780362:CGEO_RS00160
uniprot id: A0A128EE01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1780362:CGEO RS05115
gene id: 1780362:CGEO_RS05115
uniprot id: A0A128EH60
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1780362:CGEO RS06230
gene id: 1780362:CGEO_RS06230
uniprot id: A0A128EP39
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1780362:CGEO RS07925
gene id: 1780362:CGEO_RS07925
uniprot id: A0A128EEU9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1780362:CGEO RS00470
gene id: 1780362:CGEO_RS00470
uniprot id: A0A128ED35
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1780362:CGEO RS09870
gene id: 1780362:CGEO_RS09870
uniprot id: A0A128EAZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1780362:CGEO RS10000
gene id: 1780362:CGEO_RS10000
uniprot id: A0A128EB01
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS02700
gene id: 1780362:CGEO_RS02700
uniprot id: A0A128EGI9
names: Similarity
messages: Belongs to the RutC family.

1780362:CGEO RS03595
gene id: 1780362:CGEO_RS03595
uniprot id: A0A128EF55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1780362:CGEO RS09240
gene id: 1780362:CGEO_RS09240
uniprot id: A0A128EEZ3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1780362:CGEO RS03545
gene id: 1780362:CGEO_RS03545
uniprot id: A0A128EF36
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1780362:CGEO RS09190
gene id: 1780362:CGEO_RS09190
uniprot id: A0A128EA62
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1780362:CGEO RS04645
gene id: 1780362:CGEO_RS04645
uniprot id: A0A128ELL9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1780362:CGEO RS05250
gene id: 1780362:CGEO_RS05250
uniprot id: A0A128EIQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1780362:CGEO RS01095
gene id: 1780362:CGEO_RS01095
uniprot id: A0A128EDV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1780362:CGEO RS00170
gene id: 1780362:CGEO_RS00170
uniprot id: A0A128EB45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1780362:CGEO RS02615
gene id: 1780362:CGEO_RS02615
uniprot id: A0A128EPG3
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1780362:CGEO RS04460
gene id: 1780362:CGEO_RS04460
uniprot id: A0A128EJ98
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS04995
gene id: 1780362:CGEO_RS04995
uniprot id: A0A128EII0
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS04080
gene id: 1780362:CGEO_RS04080
uniprot id: A0A128EKN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS04835
gene id: 1780362:CGEO_RS04835
uniprot id: A0A128ERM7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1780362:CGEO RS02280
gene id: 1780362:CGEO_RS02280
uniprot id: A0A128EEJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS02050
gene id: 1780362:CGEO_RS02050
uniprot id: A0A128EIZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS09560
gene id: 1780362:CGEO_RS09560
uniprot id: A0A128EDL1
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS05720
gene id: 1780362:CGEO_RS05720
uniprot id: A0A128EJ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1780362:CGEO RS01045
gene id: 1780362:CGEO_RS01045
uniprot id: A0A128EDJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1780362:CGEO RS00410
gene id: 1780362:CGEO_RS00410
uniprot id: A0A128ENX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1780362:CGEO RS06195
gene id: 1780362:CGEO_RS06195
uniprot id: A0A128EGB4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1780362:CGEO RS02015
gene id: 1780362:CGEO_RS02015
uniprot id: A0A128EJJ0
names: Similarity
messages: Belongs to the peptidase S49 family.

1780362:CGEO RS07895
gene id: 1780362:CGEO_RS07895
uniprot id: A0A128EPH3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1780362:CGEO RS02495
gene id: 1780362:CGEO_RS02495
uniprot id: A0A128EER7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1780362:CGEO RS05795
gene id: 1780362:CGEO_RS05795
uniprot id: A0A128EIA4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1780362:CGEO RS06780
gene id: 1780362:CGEO_RS06780
uniprot id: A0A128EIS2
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1780362:CGEO RS01650
gene id: 1780362:CGEO_RS01650
uniprot id: A0A128EBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1780362:CGEO RS07570
gene id: 1780362:CGEO_RS07570
uniprot id: A0A128EF71
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1780362:CGEO RS00295
gene id: 1780362:CGEO_RS00295
uniprot id: A0A128EBQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1780362:CGEO RS01125
gene id: 1780362:CGEO_RS01125
uniprot id: A0A128EP70
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1780362:CGEO RS08920
gene id: 1780362:CGEO_RS08920
uniprot id: A0A128EL44
names: Similarity
messages: Belongs to the nitroreductase family.

1780362:CGEO RS00090
gene id: 1780362:CGEO_RS00090
uniprot id: A0A128EB40
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1780362:CGEO RS09900
gene id: 1780362:CGEO_RS09900
uniprot id: A0A128ECD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1780362:CGEO RS10210
gene id: 1780362:CGEO_RS10210
uniprot id: A0A128EIL6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1780362:CGEO RS09370
gene id: 1780362:CGEO_RS09370
uniprot id: A0A128EEP7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1780362:CGEO RS09575
gene id: 1780362:CGEO_RS09575
uniprot id: A0A128ELD0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1780362:CGEO RS03160
gene id: 1780362:CGEO_RS03160
uniprot id: A0A128ENI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1780362:CGEO RS02805
gene id: 1780362:CGEO_RS02805
uniprot id: A0A128EI01
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1780362:CGEO RS03525
gene id: 1780362:CGEO_RS03525
uniprot id: A0A128EE19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1780362:CGEO RS02975
gene id: 1780362:CGEO_RS02975
uniprot id: A0A128EEI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1780362:CGEO RS00125
gene id: 1780362:CGEO_RS00125
uniprot id: A0A128EBW0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1780362:CGEO RS03135
gene id: 1780362:CGEO_RS03135
uniprot id: A0A128EEP6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1780362:CGEO RS09855
gene id: 1780362:CGEO_RS09855
uniprot id: A0A128EAU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1780362:CGEO RS07920
gene id: 1780362:CGEO_RS07920
uniprot id: A0A128EET5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1780362:CGEO RS01715
gene id: 1780362:CGEO_RS01715
uniprot id: A0A128EA19
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1780362:CGEO RS07460
gene id: 1780362:CGEO_RS07460
uniprot id: A0A128EG76
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS01585
gene id: 1780362:CGEO_RS01585
uniprot id: A0A128EA73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1780362:CGEO RS08950
gene id: 1780362:CGEO_RS08950
uniprot id: A0A128EF53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1780362:CGEO RS01445
gene id: 1780362:CGEO_RS01445
uniprot id: A0A128ENV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1780362:CGEO RS02025
gene id: 1780362:CGEO_RS02025
uniprot id: A0A128EIE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1780362:CGEO RS09550
gene id: 1780362:CGEO_RS09550
uniprot id: A0A128EC98
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS01755
gene id: 1780362:CGEO_RS01755
uniprot id: A0A128ENW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1780362:CGEO RS02420
gene id: 1780362:CGEO_RS02420
uniprot id: A0A128EID2
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1780362:CGEO RS00105
gene id: 1780362:CGEO_RS00105
uniprot id: A0A128EB68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1780362:CGEO RS01830
gene id: 1780362:CGEO_RS01830
uniprot id: A0A128EP38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1780362:CGEO RS04095
gene id: 1780362:CGEO_RS04095
uniprot id: A0A128EKU1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1780362:CGEO RS02520
gene id: 1780362:CGEO_RS02520
uniprot id: A0A128EI65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1780362:CGEO RS09480
gene id: 1780362:CGEO_RS09480
uniprot id: A0A128ECH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1780362:CGEO RS06495
gene id: 1780362:CGEO_RS06495
uniprot id: A0A128EK43
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1780362:CGEO RS08120
gene id: 1780362:CGEO_RS08120
uniprot id: A0A128EG51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1780362:CGEO RS04850
gene id: 1780362:CGEO_RS04850
uniprot id: A0A128EIH7
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1780362:CGEO RS07380
gene id: 1780362:CGEO_RS07380
uniprot id: A0A128ERF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1780362:CGEO RS08620
gene id: 1780362:CGEO_RS08620
uniprot id: A0A128EGT8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1780362:CGEO RS04290
gene id: 1780362:CGEO_RS04290
uniprot id: A0A128EI61
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1780362:CGEO RS01200
gene id: 1780362:CGEO_RS01200
uniprot id: A0A128EDK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1780362:CGEO RS03315
gene id: 1780362:CGEO_RS03315
uniprot id: A0A128EN86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1780362:CGEO RS09210
gene id: 1780362:CGEO_RS09210
uniprot id: A0A128EBV5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1780362:CGEO RS04485
gene id: 1780362:CGEO_RS04485
uniprot id: A0A128EJA8
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

1780362:CGEO RS03785
gene id: 1780362:CGEO_RS03785
uniprot id: A0A128EGA4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1780362:CGEO RS09730
gene id: 1780362:CGEO_RS09730
uniprot id: A0A128EC72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1780362:CGEO RS09670
gene id: 1780362:CGEO_RS09670
uniprot id: A0A128ECE4
names: Subcellular Location Annotation
messages: Periplasm

1780362:CGEO RS07315
gene id: 1780362:CGEO_RS07315
uniprot id: A0A128EJP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Dps family.
messages: Cytoplasm

1780362:CGEO RS02430
gene id: 1780362:CGEO_RS02430
uniprot id: A0A128EEQ1
names: Similarity
messages: Belongs to the UPF0763 family.

1780362:CGEO RS00015
gene id: 1780362:CGEO_RS00015
uniprot id: A0A128EE30
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1780362:CGEO RS03125
gene id: 1780362:CGEO_RS03125
uniprot id: A0A128EJJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1780362:CGEO RS01100
gene id: 1780362:CGEO_RS01100
uniprot id: A0A128ECG6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1780362:CGEO RS08240
gene id: 1780362:CGEO_RS08240
uniprot id: A0A128EDT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1780362:CGEO RS07995
gene id: 1780362:CGEO_RS07995
uniprot id: A0A128EFR5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1780362:CGEO RS00875
gene id: 1780362:CGEO_RS00875
uniprot id: A0A128ECP0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1780362:CGEO RS03165
gene id: 1780362:CGEO_RS03165
uniprot id: A0A128EDI3
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS02320
gene id: 1780362:CGEO_RS02320
uniprot id: A0A128EJZ6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1780362:CGEO RS01135
gene id: 1780362:CGEO_RS01135
uniprot id: A0A128EAP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1780362:CGEO RS00885
gene id: 1780362:CGEO_RS00885
uniprot id: A0A128EP12
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1780362:CGEO RS07335
gene id: 1780362:CGEO_RS07335
uniprot id: A0A128EPW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1780362:CGEO RS09795
gene id: 1780362:CGEO_RS09795
uniprot id: A0A128EC21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

1780362:CGEO RS04570
gene id: 1780362:CGEO_RS04570
uniprot id: A0A128EKU5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1780362:CGEO RS03950
gene id: 1780362:CGEO_RS03950
uniprot id: A0A128EJ47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1780362:CGEO RS07325
gene id: 1780362:CGEO_RS07325
uniprot id: A0A128EFG8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1780362:CGEO RS00110
gene id: 1780362:CGEO_RS00110
uniprot id: A0A128EE14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1780362:CGEO RS01260
gene id: 1780362:CGEO_RS01260
uniprot id: A0A128EMV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1780362:CGEO RS02530
gene id: 1780362:CGEO_RS02530
uniprot id: A0A128EIA1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two zinc ions.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1780362:CGEO RS05045
gene id: 1780362:CGEO_RS05045
uniprot id: A0A128EHV1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1780362:CGEO RS01515
gene id: 1780362:CGEO_RS01515
uniprot id: A0A128ECR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1780362:CGEO RS00300
gene id: 1780362:CGEO_RS00300
uniprot id: A0A128ECZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1780362:CGEO RS07080
gene id: 1780362:CGEO_RS07080
uniprot id: A0A128EKG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1780362:CGEO RS03400
gene id: 1780362:CGEO_RS03400
uniprot id: A0A128EDV2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1780362:CGEO RS08010
gene id: 1780362:CGEO_RS08010
uniprot id: A0A128EFT3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1780362:CGEO RS02645
gene id: 1780362:CGEO_RS02645
uniprot id: A0A128EFV6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1780362:CGEO RS02175
gene id: 1780362:CGEO_RS02175
uniprot id: A0A128EEG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1780362:CGEO RS08350
gene id: 1780362:CGEO_RS08350
uniprot id: A0A128EG74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1780362:CGEO RS04085
gene id: 1780362:CGEO_RS04085
uniprot id: A0A128EJC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1780362:CGEO RS06650
gene id: 1780362:CGEO_RS06650
uniprot id: A0A128EIK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1780362:CGEO RS08485
gene id: 1780362:CGEO_RS08485
uniprot id: A0A128EHM9
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS00495
gene id: 1780362:CGEO_RS00495
uniprot id: A0A128ECV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

1780362:CGEO RS03680
gene id: 1780362:CGEO_RS03680
uniprot id: A0A128EFA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1780362:CGEO RS09030
gene id: 1780362:CGEO_RS09030
uniprot id: A0A128ECZ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1780362:CGEO RS02475
gene id: 1780362:CGEO_RS02475
uniprot id: A0A128EN47
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1780362:CGEO RS08320
gene id: 1780362:CGEO_RS08320
uniprot id: A0A128ER04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1780362:CGEO RS04295
gene id: 1780362:CGEO_RS04295
uniprot id: A0A128EJE7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1780362:CGEO RS05595
gene id: 1780362:CGEO_RS05595
uniprot id: A0A128EIH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1780362:CGEO RS01840
gene id: 1780362:CGEO_RS01840
uniprot id: A0A128ED92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1780362:CGEO RS05235
gene id: 1780362:CGEO_RS05235
uniprot id: A0A128EI13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1780362:CGEO RS04420
gene id: 1780362:CGEO_RS04420
uniprot id: A0A128EIY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1780362:CGEO RS04705
gene id: 1780362:CGEO_RS04705
uniprot id: A0A128ER08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1780362:CGEO RS05615
gene id: 1780362:CGEO_RS05615
uniprot id: A0A128EJ65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS03715
gene id: 1780362:CGEO_RS03715
uniprot id: A0A128EF79
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1780362:CGEO RS05730
gene id: 1780362:CGEO_RS05730
uniprot id: A0A128EHB3
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1780362:CGEO RS03235
gene id: 1780362:CGEO_RS03235
uniprot id: A0A128EF66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1780362:CGEO RS01450
gene id: 1780362:CGEO_RS01450
uniprot id: A0A128EAE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1780362:CGEO RS01775
gene id: 1780362:CGEO_RS01775
uniprot id: A0A128EBC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1780362:CGEO RS04865
gene id: 1780362:CGEO_RS04865
uniprot id: A0A128EJI8
names: Similarity
messages: Belongs to the peptidase A31 family.

1780362:CGEO RS04610
gene id: 1780362:CGEO_RS04610
uniprot id: A0A128EJR6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1780362:CGEO RS03980
gene id: 1780362:CGEO_RS03980
uniprot id: A0A128EKY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS02070
gene id: 1780362:CGEO_RS02070
uniprot id: A0A128EIA9
names: Similarity
messages: Belongs to the cytochrome c-552 family.

1780362:CGEO RS03215
gene id: 1780362:CGEO_RS03215
uniprot id: A0A128ENA6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1780362:CGEO RS08355
gene id: 1780362:CGEO_RS08355
uniprot id: A0A128EHQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1780362:CGEO RS00835
gene id: 1780362:CGEO_RS00835
uniprot id: A0A128EBZ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1780362:CGEO RS04770
gene id: 1780362:CGEO_RS04770
uniprot id: A0A128ELG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS09825
gene id: 1780362:CGEO_RS09825
uniprot id: A0A128EAT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1780362:CGEO RS07705
gene id: 1780362:CGEO_RS07705
uniprot id: A0A128EQJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1780362:CGEO RS02500
gene id: 1780362:CGEO_RS02500
uniprot id: A0A128EGL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1780362:CGEO RS02375
gene id: 1780362:CGEO_RS02375
uniprot id: A0A128EEM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1780362:CGEO RS08510
gene id: 1780362:CGEO_RS08510
uniprot id: A0A128EG29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1780362:CGEO RS07110
gene id: 1780362:CGEO_RS07110
uniprot id: A0A128EQJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1780362:CGEO RS06425
gene id: 1780362:CGEO_RS06425
uniprot id: A0A128EL00
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1780362:CGEO RS02505
gene id: 1780362:CGEO_RS02505
uniprot id: A0A128EES3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1780362:CGEO RS02300
gene id: 1780362:CGEO_RS02300
uniprot id: A0A128EN20
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS04310
gene id: 1780362:CGEO_RS04310
uniprot id: A0A128EI87
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1780362:CGEO RS02155
gene id: 1780362:CGEO_RS02155
uniprot id: A0A128EFU4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1780362:CGEO RS00200
gene id: 1780362:CGEO_RS00200
uniprot id: A0A128EDD6
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS09890
gene id: 1780362:CGEO_RS09890
uniprot id: A0A128ELV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1780362:CGEO RS07865
gene id: 1780362:CGEO_RS07865
uniprot id: A0A128EEY2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1780362:CGEO RS01435
gene id: 1780362:CGEO_RS01435
uniprot id: A0A128EE68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1780362:CGEO RS02510
gene id: 1780362:CGEO_RS02510
uniprot id: A0A128EG96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1780362:CGEO RS00780
gene id: 1780362:CGEO_RS00780
uniprot id: A0A128ED86
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1780362:CGEO RS04845
gene id: 1780362:CGEO_RS04845
uniprot id: A0A128EKZ2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1780362:CGEO RS07500
gene id: 1780362:CGEO_RS07500
uniprot id: A0A128EG86
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1780362:CGEO RS04480
gene id: 1780362:CGEO_RS04480
uniprot id: A0A128EJ02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1780362:CGEO RS00630
gene id: 1780362:CGEO_RS00630
uniprot id: A0A128ECL0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1780362:CGEO RS03930
gene id: 1780362:CGEO_RS03930
uniprot id: A0A128EN34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1780362:CGEO RS01975
gene id: 1780362:CGEO_RS01975
uniprot id: A0A128EMG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1780362:CGEO RS02260
gene id: 1780362:CGEO_RS02260
uniprot id: A0A128EJX6
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS05430
gene id: 1780362:CGEO_RS05430
uniprot id: A0A128EJU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1780362:CGEO RS04830
gene id: 1780362:CGEO_RS04830
uniprot id: A0A128EPT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1780362:CGEO RS08290
gene id: 1780362:CGEO_RS08290
uniprot id: A0A128EHV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1780362:CGEO RS09980
gene id: 1780362:CGEO_RS09980
uniprot id: A0A128EBV9
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS07890
gene id: 1780362:CGEO_RS07890
uniprot id: A0A128EFU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1780362:CGEO RS03050
gene id: 1780362:CGEO_RS03050
uniprot id: A0A128EEL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cytoplasm

1780362:CGEO RS07990
gene id: 1780362:CGEO_RS07990
uniprot id: A0A128EDF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1780362:CGEO RS06590
gene id: 1780362:CGEO_RS06590
uniprot id: A0A128ELV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1780362:CGEO RS00595
gene id: 1780362:CGEO_RS00595
uniprot id: A0A128EDH7
names: Similarity
messages: Belongs to the pirin family.

1780362:CGEO RS03010
gene id: 1780362:CGEO_RS03010
uniprot id: A0A128EDD2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1780362:CGEO RS01700
gene id: 1780362:CGEO_RS01700
uniprot id: A0A128EE71
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1780362:CGEO RS03655
gene id: 1780362:CGEO_RS03655
uniprot id: A0A128EFJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1780362:CGEO RS01800
gene id: 1780362:CGEO_RS01800
uniprot id: A0A128EEA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1780362:CGEO RS08930
gene id: 1780362:CGEO_RS08930
uniprot id: A0A128E9W4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1780362:CGEO RS08370
gene id: 1780362:CGEO_RS08370
uniprot id: A0A128EFX5
names: Subcellular Location Annotation
messages: Cytoplasm

1780362:CGEO RS00405
gene id: 1780362:CGEO_RS00405
uniprot id: A0A128EBI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1780362:CGEO RS01115
gene id: 1780362:CGEO_RS01115
uniprot id: A0A128EN24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1780362:CGEO RS06180
gene id: 1780362:CGEO_RS06180
uniprot id: A0A128EH55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1780362:CGEO RS01990
gene id: 1780362:CGEO_RS01990
uniprot id: A0A128EE87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS07425
gene id: 1780362:CGEO_RS07425
uniprot id: A0A128EFB6
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

1780362:CGEO RS09305
gene id: 1780362:CGEO_RS09305
uniprot id: A0A128ECM5
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS03505
gene id: 1780362:CGEO_RS03505
uniprot id: A0A128EF22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1780362:CGEO RS02310
gene id: 1780362:CGEO_RS02310
uniprot id: A0A128EID0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1780362:CGEO RS01750
gene id: 1780362:CGEO_RS01750
uniprot id: A0A128EEJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1780362:CGEO RS08740
gene id: 1780362:CGEO_RS08740
uniprot id: A0A128EFN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1780362:CGEO RS05455
gene id: 1780362:CGEO_RS05455
uniprot id: A0A128EJU0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1780362:CGEO RS03020
gene id: 1780362:CGEO_RS03020
uniprot id: A0A128ERM9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1780362:CGEO RS06980
gene id: 1780362:CGEO_RS06980
uniprot id: A0A128EM03
names: Similarity
messages: Belongs to the YggT family.

1780362:CGEO RS03955
gene id: 1780362:CGEO_RS03955
uniprot id: A0A128EKG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1780362:CGEO RS00695
gene id: 1780362:CGEO_RS00695
uniprot id: A0A128EP33
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1780362:CGEO RS01930
gene id: 1780362:CGEO_RS01930
uniprot id: A0A128E9P6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1780362:CGEO RS05600
gene id: 1780362:CGEO_RS05600
uniprot id: A0A128EHP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1780362:CGEO RS07300
gene id: 1780362:CGEO_RS07300
uniprot id: A0A128ERA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1780362:CGEO RS08080
gene id: 1780362:CGEO_RS08080
uniprot id: A0A128EFP0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1780362:CGEO RS06990
gene id: 1780362:CGEO_RS06990
uniprot id: A0A128ELQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1780362:CGEO RS04685
gene id: 1780362:CGEO_RS04685
uniprot id: A0A128EKS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1780362:CGEO RS01705
gene id: 1780362:CGEO_RS01705
uniprot id: A0A128EC55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1780362:CGEO RS01170
gene id: 1780362:CGEO_RS01170
uniprot id: A0A128EMX8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1780362:CGEO RS04675
gene id: 1780362:CGEO_RS04675
uniprot id: A0A128EKP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1780362:CGEO RS04125
gene id: 1780362:CGEO_RS04125
uniprot id: A0A128EK90
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1780362:CGEO RS09400
gene id: 1780362:CGEO_RS09400
uniprot id: A0A128EEP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1780362:CGEO RS06760
gene id: 1780362:CGEO_RS06760
uniprot id: A0A128EIP4
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS02655
gene id: 1780362:CGEO_RS02655
uniprot id: A0A128EN77
names: Similarity
messages: Belongs to the XseB family.

1780362:CGEO RS01075
gene id: 1780362:CGEO_RS01075
uniprot id: A0A128ECH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1780362:CGEO RS05210
gene id: 1780362:CGEO_RS05210
uniprot id: A0A128EGG0
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1780362:CGEO RS05380
gene id: 1780362:CGEO_RS05380
uniprot id: A0A128EKX6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1780362:CGEO RS06890
gene id: 1780362:CGEO_RS06890
uniprot id: A0A128ELJ0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1780362:CGEO RS09895
gene id: 1780362:CGEO_RS09895
uniprot id: A0A128EL10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1780362:CGEO RS09270
gene id: 1780362:CGEO_RS09270
uniprot id: A0A128EMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1780362:CGEO RS05065
gene id: 1780362:CGEO_RS05065
uniprot id: A0A128EH10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1780362:CGEO RS02720
gene id: 1780362:CGEO_RS02720
uniprot id: A0A128EHC0
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

1780362:CGEO RS09375
gene id: 1780362:CGEO_RS09375
uniprot id: A0A128EDX0
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS02540
gene id: 1780362:CGEO_RS02540
uniprot id: A0A128EEU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1780362:CGEO RS06485
gene id: 1780362:CGEO_RS06485
uniprot id: A0A128EJT1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1780362:CGEO RS02215
gene id: 1780362:CGEO_RS02215
uniprot id: A0A128EIG0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1780362:CGEO RS09355
gene id: 1780362:CGEO_RS09355
uniprot id: A0A128EMI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1780362:CGEO RS01350
gene id: 1780362:CGEO_RS01350
uniprot id: A0A128EAB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS01760
gene id: 1780362:CGEO_RS01760
uniprot id: A0A128EBD2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1780362:CGEO RS01175
gene id: 1780362:CGEO_RS01175
uniprot id: A0A128EC89
names: Similarity
messages: Belongs to the UPF0102 family.

1780362:CGEO RS04370
gene id: 1780362:CGEO_RS04370
uniprot id: A0A128EK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1780362:CGEO RS02990
gene id: 1780362:CGEO_RS02990
uniprot id: A0A128EFE4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1780362:CGEO RS04360
gene id: 1780362:CGEO_RS04360
uniprot id: A0A128EIJ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS03975
gene id: 1780362:CGEO_RS03975
uniprot id: A0A128EHK8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1780362:CGEO RS08995
gene id: 1780362:CGEO_RS08995
uniprot id: A0A128ED20
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1780362:CGEO RS09770
gene id: 1780362:CGEO_RS09770
uniprot id: A0A128EEB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1780362:CGEO RS09275
gene id: 1780362:CGEO_RS09275
uniprot id: A0A128EEU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1780362:CGEO RS01440
gene id: 1780362:CGEO_RS01440
uniprot id: A0A128EC22
names: Similarity
messages: Belongs to the GSP E family.

1780362:CGEO RS03665
gene id: 1780362:CGEO_RS03665
uniprot id: A0A128EG39
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS09125
gene id: 1780362:CGEO_RS09125
uniprot id: A0A128E9W1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1780362:CGEO RS00910
gene id: 1780362:CGEO_RS00910
uniprot id: A0A128ECB8
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1780362:CGEO RS04455
gene id: 1780362:CGEO_RS04455
uniprot id: A0A128EKT7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1780362:CGEO RS01985
gene id: 1780362:CGEO_RS01985
uniprot id: A0A128EKE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1780362:CGEO RS00620
gene id: 1780362:CGEO_RS00620
uniprot id: A0A128ECP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1780362:CGEO RS02695
gene id: 1780362:CGEO_RS02695
uniprot id: A0A128EGL0
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Homodimer.

1780362:CGEO RS02685
gene id: 1780362:CGEO_RS02685
uniprot id: A0A128EGI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1780362:CGEO RS02590
gene id: 1780362:CGEO_RS02590
uniprot id: A0A128EGP8
names: Similarity
messages: Belongs to the asparaginase 1 family.

1780362:CGEO RS01140
gene id: 1780362:CGEO_RS01140
uniprot id: A0A128ECY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1780362:CGEO RS07175
gene id: 1780362:CGEO_RS07175
uniprot id: A0A128EL91
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS06940
gene id: 1780362:CGEO_RS06940
uniprot id: A0A128EK67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1780362:CGEO RS06910
gene id: 1780362:CGEO_RS06910
uniprot id: A0A128EL64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1780362:CGEO RS07765
gene id: 1780362:CGEO_RS07765
uniprot id: A0A128EF12
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS07490
gene id: 1780362:CGEO_RS07490
uniprot id: A0A128EH54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1780362:CGEO RS09105
gene id: 1780362:CGEO_RS09105
uniprot id: A0A128ECX7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1780362:CGEO RS07610
gene id: 1780362:CGEO_RS07610
uniprot id: A0A128EJP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS04565
gene id: 1780362:CGEO_RS04565
uniprot id: A0A128EKB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1780362:CGEO RS09850
gene id: 1780362:CGEO_RS09850
uniprot id: A0A128EKQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1780362:CGEO RS07035
gene id: 1780362:CGEO_RS07035
uniprot id: A0A128EK76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1780362:CGEO RS03040
gene id: 1780362:CGEO_RS03040
uniprot id: A0A128EEL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1780362:CGEO RS02830
gene id: 1780362:CGEO_RS02830
uniprot id: A0A128EGE5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1780362:CGEO RS04055
gene id: 1780362:CGEO_RS04055
uniprot id: A0A128EJ90
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1780362:CGEO RS09120
gene id: 1780362:CGEO_RS09120
uniprot id: A0A128EA00
names: Similarity
messages: Belongs to the peptidase S51 family.

1780362:CGEO RS08760
gene id: 1780362:CGEO_RS08760
uniprot id: A0A128EJ03
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS05870
gene id: 1780362:CGEO_RS05870
uniprot id: A0A128EIA8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1780362:CGEO RS09555
gene id: 1780362:CGEO_RS09555
uniprot id: A0A128ECH0
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS00615
gene id: 1780362:CGEO_RS00615
uniprot id: A0A128EDG9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1780362:CGEO RS05835
gene id: 1780362:CGEO_RS05835
uniprot id: A0A128EIB8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1780362:CGEO RS00860
gene id: 1780362:CGEO_RS00860
uniprot id: A0A128EBX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1780362:CGEO RS01780
gene id: 1780362:CGEO_RS01780
uniprot id: A0A128EA16
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1780362:CGEO RS10015
gene id: 1780362:CGEO_RS10015
uniprot id: A0A128ECE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1780362:CGEO RS09860
gene id: 1780362:CGEO_RS09860
uniprot id: A0A128EDP3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1780362:CGEO RS08235
gene id: 1780362:CGEO_RS08235
uniprot id: A0A128EFH5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1780362:CGEO RS07945
gene id: 1780362:CGEO_RS07945
uniprot id: A0A128EET1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

1780362:CGEO RS03860
gene id: 1780362:CGEO_RS03860
uniprot id: A0A128EIK5
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1780362:CGEO RS04540
gene id: 1780362:CGEO_RS04540
uniprot id: A0A128ESF3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1780362:CGEO RS00165
gene id: 1780362:CGEO_RS00165
uniprot id: A0A128EBP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1780362:CGEO RS06555
gene id: 1780362:CGEO_RS06555
uniprot id: A0A128ELN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS07210
gene id: 1780362:CGEO_RS07210
uniprot id: A0A128ELS9
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS02815
gene id: 1780362:CGEO_RS02815
uniprot id: A0A128EH96
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1780362:CGEO RS01855
gene id: 1780362:CGEO_RS01855
uniprot id: A0A128ED42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

1780362:CGEO RS01955
gene id: 1780362:CGEO_RS01955
uniprot id: A0A128EN71
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1780362:CGEO RS02970
gene id: 1780362:CGEO_RS02970
uniprot id: A0A128EDF8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1780362:CGEO RS07410
gene id: 1780362:CGEO_RS07410
uniprot id: A0A128EH93
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS09235
gene id: 1780362:CGEO_RS09235
uniprot id: A0A128ECQ2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1780362:CGEO RS02425
gene id: 1780362:CGEO_RS02425
uniprot id: A0A128EHM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1780362:CGEO RS07075
gene id: 1780362:CGEO_RS07075
uniprot id: A0A128EKW2
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1780362:CGEO RS05435
gene id: 1780362:CGEO_RS05435
uniprot id: A0A128EGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1780362:CGEO RS04115
gene id: 1780362:CGEO_RS04115
uniprot id: A0A128EJP9
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1780362:CGEO RS01695
gene id: 1780362:CGEO_RS01695
uniprot id: A0A128EBR7
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS01470
gene id: 1780362:CGEO_RS01470
uniprot id: A0A128EC11
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1780362:CGEO RS07630
gene id: 1780362:CGEO_RS07630
uniprot id: A0A128EF33
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS05145
gene id: 1780362:CGEO_RS05145
uniprot id: A0A128EH63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

1780362:CGEO RS03310
gene id: 1780362:CGEO_RS03310
uniprot id: A0A128EG79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1780362:CGEO RS03890
gene id: 1780362:CGEO_RS03890
uniprot id: A0A128EJS7
names: Similarity
messages: Belongs to the DapA family.

1780362:CGEO RS02355
gene id: 1780362:CGEO_RS02355
uniprot id: A0A128EGU7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1780362:CGEO RS01810
gene id: 1780362:CGEO_RS01810
uniprot id: A0A128END5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1780362:CGEO RS03025
gene id: 1780362:CGEO_RS03025
uniprot id: A0A128EEK2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1780362:CGEO RS02545
gene id: 1780362:CGEO_RS02545
uniprot id: A0A128EFT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1780362:CGEO RS03710
gene id: 1780362:CGEO_RS03710
uniprot id: A0A128ELT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1780362:CGEO RS02535
gene id: 1780362:CGEO_RS02535
uniprot id: A0A128ENL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1780362:CGEO RS00855
gene id: 1780362:CGEO_RS00855
uniprot id: A0A128ECF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1780362:CGEO RS03615
gene id: 1780362:CGEO_RS03615
uniprot id: A0A128EE28
names: Similarity
messages: Belongs to the catalase family.

1780362:CGEO RS02965
gene id: 1780362:CGEO_RS02965
uniprot id: A0A128EEI3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1780362:CGEO RS05155
gene id: 1780362:CGEO_RS05155
uniprot id: A0A128EH11
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1780362:CGEO RS01410
gene id: 1780362:CGEO_RS01410
uniprot id: A0A128ECP9
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1780362:CGEO RS07020
gene id: 1780362:CGEO_RS07020
uniprot id: A0A128EL81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1780362:CGEO RS01520
gene id: 1780362:CGEO_RS01520
uniprot id: A0A128EBY9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1780362:CGEO RS00565
gene id: 1780362:CGEO_RS00565
uniprot id: A0A128ECP6
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1780362:CGEO RS09050
gene id: 1780362:CGEO_RS09050
uniprot id: A0A128E9W3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1780362:CGEO RS09285
gene id: 1780362:CGEO_RS09285
uniprot id: A0A128ECN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1780362:CGEO RS03500
gene id: 1780362:CGEO_RS03500
uniprot id: A0A128EGV2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS04825
gene id: 1780362:CGEO_RS04825
uniprot id: A0A128EJB6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1780362:CGEO RS03495
gene id: 1780362:CGEO_RS03495
uniprot id: A0A128EFG0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1780362:CGEO RS09755
gene id: 1780362:CGEO_RS09755
uniprot id: A0A128EC64
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1780362:CGEO RS05040
gene id: 1780362:CGEO_RS05040
uniprot id: A0A128EGP9
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1780362:CGEO RS02185
gene id: 1780362:CGEO_RS02185
uniprot id: A0A128EJP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS01910
gene id: 1780362:CGEO_RS01910
uniprot id: A0A128E9U4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1780362:CGEO RS01820
gene id: 1780362:CGEO_RS01820
uniprot id: A0A128E9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1780362:CGEO RS09865
gene id: 1780362:CGEO_RS09865
uniprot id: A0A128ED09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1780362:CGEO RS00525
gene id: 1780362:CGEO_RS00525
uniprot id: A0A128EBG3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1780362:CGEO RS04875
gene id: 1780362:CGEO_RS04875
uniprot id: A0A128EKU4
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1780362:CGEO RS02870
gene id: 1780362:CGEO_RS02870
uniprot id: A0A128EJI7
names: Similarity
messages: Belongs to the GARS family.

1780362:CGEO RS03865
gene id: 1780362:CGEO_RS03865
uniprot id: A0A128EEF6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS04000
gene id: 1780362:CGEO_RS04000
uniprot id: A0A128EHI4
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS04750
gene id: 1780362:CGEO_RS04750
uniprot id: A0A128ELV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1780362:CGEO RS00705
gene id: 1780362:CGEO_RS00705
uniprot id: A0A128EB28
names: Similarity
messages: Belongs to the universal stress protein A family.

1780362:CGEO RS09935
gene id: 1780362:CGEO_RS09935
uniprot id: A0A128EE57
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1780362:CGEO RS03720
gene id: 1780362:CGEO_RS03720
uniprot id: A0A128EGK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1780362:CGEO RS00580
gene id: 1780362:CGEO_RS00580
uniprot id: A0A128EPU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1780362:CGEO RS03685
gene id: 1780362:CGEO_RS03685
uniprot id: A0A128EFL4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1780362:CGEO RS06875
gene id: 1780362:CGEO_RS06875
uniprot id: A0A128ESA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1780362:CGEO RS01090
gene id: 1780362:CGEO_RS01090
uniprot id: A0A128EAM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1780362:CGEO RS05170
gene id: 1780362:CGEO_RS05170
uniprot id: A0A128EH85
names: Similarity
messages: Belongs to the peptidase M16 family.

1780362:CGEO RS06885
gene id: 1780362:CGEO_RS06885
uniprot id: A0A128ER50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS09905
gene id: 1780362:CGEO_RS09905
uniprot id: A0A128EBY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1780362:CGEO RS00895
gene id: 1780362:CGEO_RS00895
uniprot id: A0A128EAW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1780362:CGEO RS09405
gene id: 1780362:CGEO_RS09405
uniprot id: A0A128ECI4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS04110
gene id: 1780362:CGEO_RS04110
uniprot id: A0A128EJD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1780362:CGEO RS09525
gene id: 1780362:CGEO_RS09525
uniprot id: A0A128EC88
names: Similarity
messages: Belongs to the peptidase A31 family.

1780362:CGEO RS01510
gene id: 1780362:CGEO_RS01510
uniprot id: A0A128EA41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1780362:CGEO RS03625
gene id: 1780362:CGEO_RS03625
uniprot id: A0A128EE37
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS01255
gene id: 1780362:CGEO_RS01255
uniprot id: A0A128EN02
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1780362:CGEO RS02650
gene id: 1780362:CGEO_RS02650
uniprot id: A0A128EGJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1780362:CGEO RS08185
gene id: 1780362:CGEO_RS08185
uniprot id: A0A128EPM9
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS08645
gene id: 1780362:CGEO_RS08645
uniprot id: A0A128ELU6
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1780362:CGEO RS01360
gene id: 1780362:CGEO_RS01360
uniprot id: A0A128EE43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1780362:CGEO RS00635
gene id: 1780362:CGEO_RS00635
uniprot id: A0A128EB97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS08025
gene id: 1780362:CGEO_RS08025
uniprot id: A0A128EFQ8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1780362:CGEO RS04435
gene id: 1780362:CGEO_RS04435
uniprot id: A0A128ELF2
names: Similarity
messages: Belongs to the ModE family.

1780362:CGEO RS01455
gene id: 1780362:CGEO_RS01455
uniprot id: A0A128EMW7
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS01480
gene id: 1780362:CGEO_RS01480
uniprot id: A0A128EDZ7
names: Cofactor
names: Function
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Binds 1 zinc ion per subunit.

1780362:CGEO RS09735
gene id: 1780362:CGEO_RS09735
uniprot id: A0A128EAU4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1780362:CGEO RS03470
gene id: 1780362:CGEO_RS03470
uniprot id: A0A128EDZ1
names: Similarity
messages: Belongs to the DprA/Smf family.

1780362:CGEO RS09845
gene id: 1780362:CGEO_RS09845
uniprot id: A0A128ECB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1780362:CGEO RS02240
gene id: 1780362:CGEO_RS02240
uniprot id: A0A128EJR3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1780362:CGEO RS06190
gene id: 1780362:CGEO_RS06190
uniprot id: A0A128EI24
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1780362:CGEO RS05560
gene id: 1780362:CGEO_RS05560
uniprot id: A0A128EIM5
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS00130
gene id: 1780362:CGEO_RS00130
uniprot id: A0A128ED51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1780362:CGEO RS02640
gene id: 1780362:CGEO_RS02640
uniprot id: A0A128EI63
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1780362:CGEO RS03225
gene id: 1780362:CGEO_RS03225
uniprot id: A0A128EDP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1780362:CGEO RS06175
gene id: 1780362:CGEO_RS06175
uniprot id: A0A128EQ22
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS02305
gene id: 1780362:CGEO_RS02305
uniprot id: A0A128ENH1
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1780362:CGEO RS06880
gene id: 1780362:CGEO_RS06880
uniprot id: A0A128EHR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1780362:CGEO RS00690
gene id: 1780362:CGEO_RS00690
uniprot id: A0A128ECL2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1780362:CGEO RS07670
gene id: 1780362:CGEO_RS07670
uniprot id: A0A128EF11
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS08580
gene id: 1780362:CGEO_RS08580
uniprot id: A0A128EE59
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1780362:CGEO RS04365
gene id: 1780362:CGEO_RS04365
uniprot id: A0A128EIU6
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS08980
gene id: 1780362:CGEO_RS08980
uniprot id: A0A128EC75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1780362:CGEO RS07455
gene id: 1780362:CGEO_RS07455
uniprot id: A0A128EGA3
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS02745
gene id: 1780362:CGEO_RS02745
uniprot id: A0A128EGJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1780362:CGEO RS08665
gene id: 1780362:CGEO_RS08665
uniprot id: A0A128EJ76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1780362:CGEO RS07030
gene id: 1780362:CGEO_RS07030
uniprot id: A0A128ES02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1780362:CGEO RS08475
gene id: 1780362:CGEO_RS08475
uniprot id: A0A128EFG3
names: Similarity
messages: Belongs to the UPF0423 family.

1780362:CGEO RS08145
gene id: 1780362:CGEO_RS08145
uniprot id: A0A128EQW4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1780362:CGEO RS07750
gene id: 1780362:CGEO_RS07750
uniprot id: A0A128EGG6
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

1780362:CGEO RS02875
gene id: 1780362:CGEO_RS02875
uniprot id: A0A128EIU7
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS02525
gene id: 1780362:CGEO_RS02525
uniprot id: A0A128EGP6
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS08125
gene id: 1780362:CGEO_RS08125
uniprot id: A0A128EDM6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1780362:CGEO RS01770
gene id: 1780362:CGEO_RS01770
uniprot id: A0A128ECA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1780362:CGEO RS09205
gene id: 1780362:CGEO_RS09205
uniprot id: A0A128EBK0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1780362:CGEO RS02415
gene id: 1780362:CGEO_RS02415
uniprot id: A0A128EGS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1780362:CGEO RS05010
gene id: 1780362:CGEO_RS05010
uniprot id: A0A128EH01
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1780362:CGEO RS06010
gene id: 1780362:CGEO_RS06010
uniprot id: A0A128EKB4
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS05385
gene id: 1780362:CGEO_RS05385
uniprot id: A0A128ELX6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1780362:CGEO RS08455
gene id: 1780362:CGEO_RS08455
uniprot id: A0A128EFZ6
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS02905
gene id: 1780362:CGEO_RS02905
uniprot id: A0A128EFF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1780362:CGEO RS09885
gene id: 1780362:CGEO_RS09885
uniprot id: A0A128EAY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1780362:CGEO RS01745
gene id: 1780362:CGEO_RS01745
uniprot id: A0A128EMM5
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1780362:CGEO RS06330
gene id: 1780362:CGEO_RS06330
uniprot id: A0A128EKX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1780362:CGEO RS00880
gene id: 1780362:CGEO_RS00880
uniprot id: A0A128EAY3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1780362:CGEO RS08880
gene id: 1780362:CGEO_RS08880
uniprot id: A0A128EB61
names: Similarity
messages: Belongs to the class-I fumarase family.

1780362:CGEO RS03515
gene id: 1780362:CGEO_RS03515
uniprot id: A0A128EF58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1780362:CGEO RS03075
gene id: 1780362:CGEO_RS03075
uniprot id: A0A128EJH4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1780362:CGEO RS05125
gene id: 1780362:CGEO_RS05125
uniprot id: A0A128EQR0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1780362:CGEO RS00430
gene id: 1780362:CGEO_RS00430
uniprot id: A0A128EDN8
names: Subcellular Location Annotation
messages: Membrane

1780362:CGEO RS08295
gene id: 1780362:CGEO_RS08295
uniprot id: A0A128EG53
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS04900
gene id: 1780362:CGEO_RS04900
uniprot id: A0A128EHQ8
names: Similarity
messages: Belongs to the HupF/HypC family.

1780362:CGEO RS09110
gene id: 1780362:CGEO_RS09110
uniprot id: A0A128EA46
names: Similarity
messages: Belongs to the PdxS/SNZ family.

1780362:CGEO RS04270
gene id: 1780362:CGEO_RS04270
uniprot id: A0A128ELY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1780362:CGEO RS00610
gene id: 1780362:CGEO_RS00610
uniprot id: A0A128EB67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1780362:CGEO RS01235
gene id: 1780362:CGEO_RS01235
uniprot id: A0A128ECV4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1780362:CGEO RS00050
gene id: 1780362:CGEO_RS00050
uniprot id: A0A128ECG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1780362:CGEO RS06840
gene id: 1780362:CGEO_RS06840
uniprot id: A0A128ESK8
names: Similarity
messages: Belongs to the LOG family.

1780362:CGEO RS08340
gene id: 1780362:CGEO_RS08340
uniprot id: A0A128EDX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1780362:CGEO RS08695
gene id: 1780362:CGEO_RS08695
uniprot id: A0A128EFS7
names: Cofactor
names: Similarity
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.

1780362:CGEO RS01545
gene id: 1780362:CGEO_RS01545
uniprot id: A0A128ECP5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1780362:CGEO RS03590
gene id: 1780362:CGEO_RS03590
uniprot id: A0A128EE33
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).

1780362:CGEO RS01040
gene id: 1780362:CGEO_RS01040
uniprot id: A0A128EAQ1
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1780362:CGEO RS03790
gene id: 1780362:CGEO_RS03790
uniprot id: A0A128EEC3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1780362:CGEO RS02675
gene id: 1780362:CGEO_RS02675
uniprot id: A0A128EIB5
names: Subcellular Location Annotation
messages: Cytoplasm

1780362:CGEO RS01495
gene id: 1780362:CGEO_RS01495
uniprot id: A0A128EC00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1780362:CGEO RS09170
gene id: 1780362:CGEO_RS09170
uniprot id: A0A128ECZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1780362:CGEO RS02490
gene id: 1780362:CGEO_RS02490
uniprot id: A0A128EEQ9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1780362:CGEO RS05735
gene id: 1780362:CGEO_RS05735
uniprot id: A0A128EIC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1780362:CGEO RS06580
gene id: 1780362:CGEO_RS06580
uniprot id: A0A128EIE0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1780362:CGEO RS09815
gene id: 1780362:CGEO_RS09815
uniprot id: A0A128EDD7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.