1775880:D3791 RS16315
gene id: 1775880:D3791_RS16315
uniprot id: A0A6H0SMJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS07090
gene id: 1775880:D3791_RS07090
uniprot id: A0A6H0SKH4
names: Similarity
messages: Belongs to the universal stress protein A family.

1775880:D3791 RS09935
gene id: 1775880:D3791_RS09935
uniprot id: A0A6H0SIU4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1775880:D3791 RS02920
gene id: 1775880:D3791_RS02920
uniprot id: A0A6H0SIK3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1775880:D3791 RS02030
gene id: 1775880:D3791_RS02030
uniprot id: A0A6H0SJ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1775880:D3791 RS08745
gene id: 1775880:D3791_RS08745
uniprot id: A0A6H0SHQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS10540
gene id: 1775880:D3791_RS10540
uniprot id: A0A6H0SNL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1775880:D3791 RS14200
gene id: 1775880:D3791_RS14200
uniprot id: A0A6H0SNY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1775880:D3791 RS01160
gene id: 1775880:D3791_RS01160
uniprot id: A0A6H0SDX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1775880:D3791 RS09575
gene id: 1775880:D3791_RS09575
uniprot id: A0A6H0SMX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1775880:D3791 RS15310
gene id: 1775880:D3791_RS15310
uniprot id: A0A6H0SPS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS15235
gene id: 1775880:D3791_RS15235
uniprot id: A0A6H0SP11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS08500
gene id: 1775880:D3791_RS08500
uniprot id: A0A6H0SME4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1775880:D3791 RS02625
gene id: 1775880:D3791_RS02625
uniprot id: A0A6H0SI58
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1775880:D3791 RS03125
gene id: 1775880:D3791_RS03125
uniprot id: A0A6H0SFX6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1775880:D3791 RS11440
gene id: 1775880:D3791_RS11440
uniprot id: A0A6H0SKJ4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1775880:D3791 RS13060
gene id: 1775880:D3791_RS13060
uniprot id: A0A6H0SNM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS09295
gene id: 1775880:D3791_RS09295
uniprot id: A0A6H0SN42
names: Similarity
messages: Belongs to the universal stress protein A family.

1775880:D3791 RS08930
gene id: 1775880:D3791_RS08930
uniprot id: A0A6H0SJ85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1775880:D3791 RS01695
gene id: 1775880:D3791_RS01695
uniprot id: A0A6H0SIY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS05175
gene id: 1775880:D3791_RS05175
uniprot id: A0A6H0SFZ7
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1775880:D3791 RS04450
gene id: 1775880:D3791_RS04450
uniprot id: A0A6H0SIR1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1775880:D3791 RS03870
gene id: 1775880:D3791_RS03870
uniprot id: A0A6H0SG24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1775880:D3791 RS05535
gene id: 1775880:D3791_RS05535
uniprot id: A0A6H0SJP9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS00935
gene id: 1775880:D3791_RS00935
uniprot id: A0A6H0SGZ2
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1775880:D3791 RS13695
gene id: 1775880:D3791_RS13695
uniprot id: A0A6H0SKY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1775880:D3791 RS00275
gene id: 1775880:D3791_RS00275
uniprot id: A0A6H0SH79
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1775880:D3791 RS01025
gene id: 1775880:D3791_RS01025
uniprot id: A0A6H0SEL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1775880:D3791 RS05835
gene id: 1775880:D3791_RS05835
uniprot id: A0A6H0SK21
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1775880:D3791 RS04445
gene id: 1775880:D3791_RS04445
uniprot id: A0A6H0SGZ3
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS03595
gene id: 1775880:D3791_RS03595
uniprot id: A0A6H0SIN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1775880:D3791 RS11310
gene id: 1775880:D3791_RS11310
uniprot id: A0A6H0SJI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1775880:D3791 RS02175
gene id: 1775880:D3791_RS02175
uniprot id: A0A6H0SHL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS04430
gene id: 1775880:D3791_RS04430
uniprot id: A0A6H0SKD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1775880:D3791 RS08310
gene id: 1775880:D3791_RS08310
uniprot id: A0A6H0SLB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1775880:D3791 RS16340
gene id: 1775880:D3791_RS16340
uniprot id: A0A6H0SQ30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1775880:D3791 RS02200
gene id: 1775880:D3791_RS02200
uniprot id: A0A6H0SFW3
names: Similarity
messages: Belongs to the citrate synthase family.

1775880:D3791 RS16590
gene id: 1775880:D3791_RS16590
uniprot id: A0A6H0SN70
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1775880:D3791 RS14455
gene id: 1775880:D3791_RS14455
uniprot id: A0A6H0SLJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1775880:D3791 RS00925
gene id: 1775880:D3791_RS00925
uniprot id: A0A6H0SH94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1775880:D3791 RS00525
gene id: 1775880:D3791_RS00525
uniprot id: A0A6H0SIB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1775880:D3791 RS08315
gene id: 1775880:D3791_RS08315
uniprot id: A0A6H0SJ22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1775880:D3791 RS16015
gene id: 1775880:D3791_RS16015
uniprot id: A0A6H0SPE3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1775880:D3791 RS07420
gene id: 1775880:D3791_RS07420
uniprot id: A0A6H0SHV4
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS04635
gene id: 1775880:D3791_RS04635
uniprot id: A0A6H0SJF7
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS11225
gene id: 1775880:D3791_RS11225
uniprot id: A0A6H0SMG7
names: Similarity
messages: Belongs to the WXG100 family.

1775880:D3791 RS00285
gene id: 1775880:D3791_RS00285
uniprot id: A0A6H0SI73
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1775880:D3791 RS02190
gene id: 1775880:D3791_RS02190
uniprot id: A0A6H0SFF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1775880:D3791 RS12060
gene id: 1775880:D3791_RS12060
uniprot id: A0A6H0SKW0
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1775880:D3791 RS02180
gene id: 1775880:D3791_RS02180
uniprot id: A0A6H0SEG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS03795
gene id: 1775880:D3791_RS03795
uniprot id: A0A6H0SG99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1775880:D3791 RS15745
gene id: 1775880:D3791_RS15745
uniprot id: A0A6H0SQ04
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1775880:D3791 RS04365
gene id: 1775880:D3791_RS04365
uniprot id: A0A6H0SH07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1775880:D3791 RS00865
gene id: 1775880:D3791_RS00865
uniprot id: A0A6H0SIH3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS08720
gene id: 1775880:D3791_RS08720
uniprot id: A0A6H0SIH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1775880:D3791 RS16190
gene id: 1775880:D3791_RS16190
uniprot id: A0A6H0SLB3
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1775880:D3791 RS00270
gene id: 1775880:D3791_RS00270
uniprot id: A0A6H0SEG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1775880:D3791 RS11905
gene id: 1775880:D3791_RS11905
uniprot id: A0A6H0SKP8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1775880:D3791 RS07920
gene id: 1775880:D3791_RS07920
uniprot id: A0A6H0SIB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS02900
gene id: 1775880:D3791_RS02900
uniprot id: A0A6H0SHY9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1775880:D3791 RS01675
gene id: 1775880:D3791_RS01675
uniprot id: A0A6H0SEK3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1775880:D3791 RS12395
gene id: 1775880:D3791_RS12395
uniprot id: A0A6H0SKA5
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS15845
gene id: 1775880:D3791_RS15845
uniprot id: A0A6H0SLX4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1775880:D3791 RS01595
gene id: 1775880:D3791_RS01595
uniprot id: A0A6H0SEW0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1775880:D3791 RS16580
gene id: 1775880:D3791_RS16580
uniprot id: A0A6H0SMP1
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1775880:D3791 RS09375
gene id: 1775880:D3791_RS09375
uniprot id: A0A6H0SJ15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1775880:D3791 RS01095
gene id: 1775880:D3791_RS01095
uniprot id: A0A6H0SH24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1775880:D3791 RS02830
gene id: 1775880:D3791_RS02830
uniprot id: A0A6H0SJI5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1775880:D3791 RS09595
gene id: 1775880:D3791_RS09595
uniprot id: A0A6H0SL96
names: Similarity
messages: Belongs to the AAA ATPase family.

1775880:D3791 RS15710
gene id: 1775880:D3791_RS15710
uniprot id: A0A6H0SNE0
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1775880:D3791 RS15655
gene id: 1775880:D3791_RS15655
uniprot id: A0A6H0SP84
names: Similarity
messages: Belongs to the UPF0102 family.

1775880:D3791 RS10530
gene id: 1775880:D3791_RS10530
uniprot id: A0A6H0SNE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1775880:D3791 RS00485
gene id: 1775880:D3791_RS00485
uniprot id: A0A6H0SH18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1775880:D3791 RS16205
gene id: 1775880:D3791_RS16205
uniprot id: A0A6H0SQ84
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1775880:D3791 RS09850
gene id: 1775880:D3791_RS09850
uniprot id: A0A6H0SJ16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1775880:D3791 RS00655
gene id: 1775880:D3791_RS00655
uniprot id: A0A6H0SDP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1775880:D3791 RS00580
gene id: 1775880:D3791_RS00580
uniprot id: A0A6H0SIC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS00690
gene id: 1775880:D3791_RS00690
uniprot id: A0A6H0SHE5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1775880:D3791 RS04060
gene id: 1775880:D3791_RS04060
uniprot id: A0A6H0SIJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1775880:D3791 RS14545
gene id: 1775880:D3791_RS14545
uniprot id: A0A6H0SM20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1775880:D3791 RS03170
gene id: 1775880:D3791_RS03170
uniprot id: A0A6H0SEZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS03405
gene id: 1775880:D3791_RS03405
uniprot id: A0A6H0SF34
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1775880:D3791 RS03030
gene id: 1775880:D3791_RS03030
uniprot id: A0A6H0SGB6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1775880:D3791 RS02580
gene id: 1775880:D3791_RS02580
uniprot id: A0A6H0SHT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1775880:D3791 RS09510
gene id: 1775880:D3791_RS09510
uniprot id: A0A6H0SLV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS01615
gene id: 1775880:D3791_RS01615
uniprot id: A0A6H0SE62
names: Similarity
messages: Belongs to the glutamine synthetase family.

1775880:D3791 RS01190
gene id: 1775880:D3791_RS01190
uniprot id: A0A6H0SEN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1775880:D3791 RS04045
gene id: 1775880:D3791_RS04045
uniprot id: A0A6H0SG54
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS14905
gene id: 1775880:D3791_RS14905
uniprot id: A0A6H0SQM6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1775880:D3791 RS09855
gene id: 1775880:D3791_RS09855
uniprot id: A0A6H0SLU1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1775880:D3791 RS07975
gene id: 1775880:D3791_RS07975
uniprot id: A0A6H0SIC2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1775880:D3791 RS14405
gene id: 1775880:D3791_RS14405
uniprot id: A0A6H0SLI9
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1775880:D3791 RS13475
gene id: 1775880:D3791_RS13475
uniprot id: A0A6H0SKU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1775880:D3791 RS03035
gene id: 1775880:D3791_RS03035
uniprot id: A0A6H0SJM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1775880:D3791 RS03045
gene id: 1775880:D3791_RS03045
uniprot id: A0A6H0SID8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1775880:D3791 RS08865
gene id: 1775880:D3791_RS08865
uniprot id: A0A6H0SLC6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

1775880:D3791 RS07940
gene id: 1775880:D3791_RS07940
uniprot id: A0A6H0SM45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1775880:D3791 RS05630
gene id: 1775880:D3791_RS05630
uniprot id: A0A6H0SKZ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1775880:D3791 RS02910
gene id: 1775880:D3791_RS02910
uniprot id: A0A6H0SF71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1775880:D3791 RS15000
gene id: 1775880:D3791_RS15000
uniprot id: A0A6H0SM97
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS07525
gene id: 1775880:D3791_RS07525
uniprot id: A0A6H0SKV5
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS15855
gene id: 1775880:D3791_RS15855
uniprot id: A0A6H0SN52
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1775880:D3791 RS16395
gene id: 1775880:D3791_RS16395
uniprot id: A0A6H0SQ40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1775880:D3791 RS01930
gene id: 1775880:D3791_RS01930
uniprot id: A0A6H0SHG8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1775880:D3791 RS01665
gene id: 1775880:D3791_RS01665
uniprot id: A0A6H0SHC3
names: Similarity
messages: Belongs to the YggT family.

1775880:D3791 RS03105
gene id: 1775880:D3791_RS03105
uniprot id: A0A6H0SGA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1775880:D3791 RS13975
gene id: 1775880:D3791_RS13975
uniprot id: A0A6H0SQ50
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1775880:D3791 RS10535
gene id: 1775880:D3791_RS10535
uniprot id: A0A6H0SJD2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1775880:D3791 RS07005
gene id: 1775880:D3791_RS07005
uniprot id: A0A6H0SKL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1775880:D3791 RS00490
gene id: 1775880:D3791_RS00490
uniprot id: A0A6H0SF05
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1775880:D3791 RS08140
gene id: 1775880:D3791_RS08140
uniprot id: A0A6H0SHX3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1775880:D3791 RS01690
gene id: 1775880:D3791_RS01690
uniprot id: A0A6H0SFM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1775880:D3791 RS07375
gene id: 1775880:D3791_RS07375
uniprot id: A0A6H0SIG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS02945
gene id: 1775880:D3791_RS02945
uniprot id: A0A6H0SIB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1775880:D3791 RS08265
gene id: 1775880:D3791_RS08265
uniprot id: A0A6H0SJ10
names: Similarity
messages: Belongs to the thioredoxin family.

1775880:D3791 RS03650
gene id: 1775880:D3791_RS03650
uniprot id: A0A6H0SIP2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1775880:D3791 RS13575
gene id: 1775880:D3791_RS13575
uniprot id: A0A6H0SLM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1775880:D3791 RS12855
gene id: 1775880:D3791_RS12855
uniprot id: A0A6H0SMU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1775880:D3791 RS03080
gene id: 1775880:D3791_RS03080
uniprot id: A0A6H0SGC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1775880:D3791 RS14555
gene id: 1775880:D3791_RS14555
uniprot id: A0A6H0SKI0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1775880:D3791 RS03690
gene id: 1775880:D3791_RS03690
uniprot id: A0A6H0SIY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1775880:D3791 RS11285
gene id: 1775880:D3791_RS11285
uniprot id: A0A6H0SMH6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1775880:D3791 RS06405
gene id: 1775880:D3791_RS06405
uniprot id: A0A6H0SJS5
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS08125
gene id: 1775880:D3791_RS08125
uniprot id: A0A6H0SIT6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1775880:D3791 RS02035
gene id: 1775880:D3791_RS02035
uniprot id: A0A6H0SF40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1775880:D3791 RS13170
gene id: 1775880:D3791_RS13170
uniprot id: A0A6H0SNP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1775880:D3791 RS09750
gene id: 1775880:D3791_RS09750
uniprot id: A0A6H0SLS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1775880:D3791 RS02600
gene id: 1775880:D3791_RS02600
uniprot id: A0A6H0SID6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1775880:D3791 RS13750
gene id: 1775880:D3791_RS13750
uniprot id: A0A6H0SNR1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1775880:D3791 RS03640
gene id: 1775880:D3791_RS03640
uniprot id: A0A6H0SJY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1775880:D3791 RS02960
gene id: 1775880:D3791_RS02960
uniprot id: A0A6H0SEV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1775880:D3791 RS00780
gene id: 1775880:D3791_RS00780
uniprot id: A0A6H0SGW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1775880:D3791 RS12840
gene id: 1775880:D3791_RS12840
uniprot id: A0A6H0SKI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS09430
gene id: 1775880:D3791_RS09430
uniprot id: A0A6H0SI20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1775880:D3791 RS03725
gene id: 1775880:D3791_RS03725
uniprot id: A0A6H0SND2
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1775880:D3791 RS15620
gene id: 1775880:D3791_RS15620
uniprot id: A0A6H0SM71
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1775880:D3791 RS04630
gene id: 1775880:D3791_RS04630
uniprot id: A0A6H0SGP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1775880:D3791 RS03015
gene id: 1775880:D3791_RS03015
uniprot id: A0A6H0SF90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1775880:D3791 RS05660
gene id: 1775880:D3791_RS05660
uniprot id: A0A6H0SG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS04190
gene id: 1775880:D3791_RS04190
uniprot id: A0A6H0SGH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS02930
gene id: 1775880:D3791_RS02930
uniprot id: A0A6H0SG96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1775880:D3791 RS13150
gene id: 1775880:D3791_RS13150
uniprot id: A0A6H0SJT8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1775880:D3791 RS12955
gene id: 1775880:D3791_RS12955
uniprot id: A0A6H0SPL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1775880:D3791 RS02130
gene id: 1775880:D3791_RS02130
uniprot id: A0A6H0SES9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1775880:D3791 RS04935
gene id: 1775880:D3791_RS04935
uniprot id: A0A6H0SJE1
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS03055
gene id: 1775880:D3791_RS03055
uniprot id: A0A6H0SI24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1775880:D3791 RS02560
gene id: 1775880:D3791_RS02560
uniprot id: A0A6H0SJD4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1775880:D3791 RS07665
gene id: 1775880:D3791_RS07665
uniprot id: A0A6H0SLZ7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1775880:D3791 RS05480
gene id: 1775880:D3791_RS05480
uniprot id: A0A6H0SGW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS08290
gene id: 1775880:D3791_RS08290
uniprot id: A0A6H0SKN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1775880:D3791 RS11025
gene id: 1775880:D3791_RS11025
uniprot id: A0A6H0SKD4
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1775880:D3791 RS08490
gene id: 1775880:D3791_RS08490
uniprot id: A0A6H0SLE0
names: Similarity
messages: Belongs to the universal stress protein A family.

1775880:D3791 RS14400
gene id: 1775880:D3791_RS14400
uniprot id: A0A6H0SL43
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1775880:D3791 RS16005
gene id: 1775880:D3791_RS16005
uniprot id: A0A6H0SPW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS10465
gene id: 1775880:D3791_RS10465
uniprot id: A0A6H0SND8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1775880:D3791 RS04015
gene id: 1775880:D3791_RS04015
uniprot id: A0A6H0SFE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS09910
gene id: 1775880:D3791_RS09910
uniprot id: A0A6H0SLV2
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS03415
gene id: 1775880:D3791_RS03415
uniprot id: A0A6H0SG31
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1775880:D3791 RS12660
gene id: 1775880:D3791_RS12660
uniprot id: A0A6H0SPG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS10200
gene id: 1775880:D3791_RS10200
uniprot id: A0A6H0SLK5
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1775880:D3791 RS03360
gene id: 1775880:D3791_RS03360
uniprot id: A0A6H0SFE7
names: Similarity
messages: Belongs to the UPF0234 family.

1775880:D3791 RS15365
gene id: 1775880:D3791_RS15365
uniprot id: A0A6H0SM21
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1775880:D3791 RS16575
gene id: 1775880:D3791_RS16575
uniprot id: A0A6H0SMB3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1775880:D3791 RS11215
gene id: 1775880:D3791_RS11215
uniprot id: A0A6H0SNQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1775880:D3791 RS16650
gene id: 1775880:D3791_RS16650
uniprot id: A0A6H0SMF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1775880:D3791 RS02705
gene id: 1775880:D3791_RS02705
uniprot id: A0A6H0SG59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1775880:D3791 RS08295
gene id: 1775880:D3791_RS08295
uniprot id: A0A6H0SHI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1775880:D3791 RS07245
gene id: 1775880:D3791_RS07245
uniprot id: A0A6H0SKK3
names: Similarity
messages: Belongs to the PrpF family.

1775880:D3791 RS14335
gene id: 1775880:D3791_RS14335
uniprot id: A0A6H0SNK4
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS15550
gene id: 1775880:D3791_RS15550
uniprot id: A0A6H0SMJ8
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1775880:D3791 RS12145
gene id: 1775880:D3791_RS12145
uniprot id: A0A6H0SJB7
names: Similarity
messages: Belongs to the FBPase class 2 family.

1775880:D3791 RS00385
gene id: 1775880:D3791_RS00385
uniprot id: A0A6H0SEI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1775880:D3791 RS14845
gene id: 1775880:D3791_RS14845
uniprot id: A0A6H0SPJ9
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS02965
gene id: 1775880:D3791_RS02965
uniprot id: A0A6H0SF81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1775880:D3791 RS07070
gene id: 1775880:D3791_RS07070
uniprot id: A0A6H0SLP9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1775880:D3791 RS14195
gene id: 1775880:D3791_RS14195
uniprot id: A0A6H0SL74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1775880:D3791 RS00850
gene id: 1775880:D3791_RS00850
uniprot id: A0A6H0SER1
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1775880:D3791 RS04030
gene id: 1775880:D3791_RS04030
uniprot id: A0A6H0SJ46
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS14630
gene id: 1775880:D3791_RS14630
uniprot id: A0A6H0SPF9
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS09640
gene id: 1775880:D3791_RS09640
uniprot id: A0A6H0SJK3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1775880:D3791 RS04145
gene id: 1775880:D3791_RS04145
uniprot id: A0A6H0SJ64
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1775880:D3791 RS16560
gene id: 1775880:D3791_RS16560
uniprot id: A0A6H0SN34
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1775880:D3791 RS12110
gene id: 1775880:D3791_RS12110
uniprot id: A0A6H0SN55
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1775880:D3791 RS00430
gene id: 1775880:D3791_RS00430
uniprot id: A0A6H0SDK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1775880:D3791 RS11970
gene id: 1775880:D3791_RS11970
uniprot id: A0A6H0SME1
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1775880:D3791 RS03935
gene id: 1775880:D3791_RS03935
uniprot id: A0A6H0SK37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1775880:D3791 RS12075
gene id: 1775880:D3791_RS12075
uniprot id: A0A6H0SNN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1775880:D3791 RS05270
gene id: 1775880:D3791_RS05270
uniprot id: A0A6H0SNC4
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1775880:D3791 RS13175
gene id: 1775880:D3791_RS13175
uniprot id: A0A6H0SLG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1775880:D3791 RS16370
gene id: 1775880:D3791_RS16370
uniprot id: A0A6H0SMK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1775880:D3791 RS02925
gene id: 1775880:D3791_RS02925
uniprot id: A0A6H0SNB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1775880:D3791 RS08260
gene id: 1775880:D3791_RS08260
uniprot id: A0A6H0SLA1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1775880:D3791 RS03195
gene id: 1775880:D3791_RS03195
uniprot id: A0A6H0SJP8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1775880:D3791 RS05205
gene id: 1775880:D3791_RS05205
uniprot id: A0A6H0SGR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS00165
gene id: 1775880:D3791_RS00165
uniprot id: A0A6H0SDS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1775880:D3791 RS00280
gene id: 1775880:D3791_RS00280
uniprot id: A0A6H0SEY0
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1775880:D3791 RS03840
gene id: 1775880:D3791_RS03840
uniprot id: A0A6H0SFN4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1775880:D3791 RS15250
gene id: 1775880:D3791_RS15250
uniprot id: A0A6H0SLJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1775880:D3791 RS15605
gene id: 1775880:D3791_RS15605
uniprot id: A0A6H0SP76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1775880:D3791 RS01185
gene id: 1775880:D3791_RS01185
uniprot id: A0A6H0SIP3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1775880:D3791 RS04080
gene id: 1775880:D3791_RS04080
uniprot id: A0A6H0SGF1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1775880:D3791 RS03665
gene id: 1775880:D3791_RS03665
uniprot id: A0A6H0SF83
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1775880:D3791 RS05460
gene id: 1775880:D3791_RS05460
uniprot id: A0A6H0SH51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS15695
gene id: 1775880:D3791_RS15695
uniprot id: A0A6H0SPR5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1775880:D3791 RS00755
gene id: 1775880:D3791_RS00755
uniprot id: A0A6H0SIF3
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS05300
gene id: 1775880:D3791_RS05300
uniprot id: A0A6H0SJS7
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1775880:D3791 RS13755
gene id: 1775880:D3791_RS13755
uniprot id: A0A6H0SLN4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1775880:D3791 RS01415
gene id: 1775880:D3791_RS01415
uniprot id: A0A6H0SEF8
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1775880:D3791 RS12940
gene id: 1775880:D3791_RS12940
uniprot id: A0A6H0SNL1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1775880:D3791 RS01620
gene id: 1775880:D3791_RS01620
uniprot id: A0A6H0SEJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1775880:D3791 RS00455
gene id: 1775880:D3791_RS00455
uniprot id: A0A6H0SEJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1775880:D3791 RS03065
gene id: 1775880:D3791_RS03065
uniprot id: A0A6H0SFA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1775880:D3791 RS03180
gene id: 1775880:D3791_RS03180
uniprot id: A0A6H0SFY4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS03535
gene id: 1775880:D3791_RS03535
uniprot id: A0A6H0SFV8
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1775880:D3791 RS04025
gene id: 1775880:D3791_RS04025
uniprot id: A0A6H0SGE1
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS11510
gene id: 1775880:D3791_RS11510
uniprot id: A0A6H0SKH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1775880:D3791 RS14435
gene id: 1775880:D3791_RS14435
uniprot id: A0A6H0SM01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1775880:D3791 RS10215
gene id: 1775880:D3791_RS10215
uniprot id: A0A6H0SJF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1775880:D3791 RS13930
gene id: 1775880:D3791_RS13930
uniprot id: A0A6H0SL22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS12135
gene id: 1775880:D3791_RS12135
uniprot id: A0A6H0SKU0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1775880:D3791 RS09085
gene id: 1775880:D3791_RS09085
uniprot id: A0A6H0SMP3
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS15765
gene id: 1775880:D3791_RS15765
uniprot id: A0A6H0SLZ8
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS02695
gene id: 1775880:D3791_RS02695
uniprot id: A0A6H0SFP0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1775880:D3791 RS16460
gene id: 1775880:D3791_RS16460
uniprot id: A0A6H0SLG1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1775880:D3791 RS12430
gene id: 1775880:D3791_RS12430
uniprot id: A0A6H0SK38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1775880:D3791 RS15900
gene id: 1775880:D3791_RS15900
uniprot id: A0A6H0SL69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1775880:D3791 RS04700
gene id: 1775880:D3791_RS04700
uniprot id: A0A6H0SH69
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1775880:D3791 RS03245
gene id: 1775880:D3791_RS03245
uniprot id: A0A6H0SGF5
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS13450
gene id: 1775880:D3791_RS13450
uniprot id: A0A6H0SL16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1775880:D3791 RS13995
gene id: 1775880:D3791_RS13995
uniprot id: A0A6H0SNE3
names: Subcellular Location Annotation
messages: Cytoplasm

1775880:D3791 RS13705
gene id: 1775880:D3791_RS13705
uniprot id: A0A6H0SLM4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1775880:D3791 RS00120
gene id: 1775880:D3791_RS00120
uniprot id: A0A6H0SED8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1775880:D3791 RS03090
gene id: 1775880:D3791_RS03090
uniprot id: A0A6H0SRM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1775880:D3791 RS12290
gene id: 1775880:D3791_RS12290
uniprot id: A0A6H0SKW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS13245
gene id: 1775880:D3791_RS13245
uniprot id: A0A6H0SKQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1775880:D3791 RS11195
gene id: 1775880:D3791_RS11195
uniprot id: A0A6H0SJW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1775880:D3791 RS03075
gene id: 1775880:D3791_RS03075
uniprot id: A0A6H0SIN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1775880:D3791 RS15470
gene id: 1775880:D3791_RS15470
uniprot id: A0A6H0SPV5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1775880:D3791 RS13055
gene id: 1775880:D3791_RS13055
uniprot id: A0A6H0SKV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS06980
gene id: 1775880:D3791_RS06980
uniprot id: A0A6H0SK12
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1775880:D3791 RS04165
gene id: 1775880:D3791_RS04165
uniprot id: A0A6H0SIY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1775880:D3791 RS13035
gene id: 1775880:D3791_RS13035
uniprot id: A0A6H0SLA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS00810
gene id: 1775880:D3791_RS00810
uniprot id: A0A6H0SIG3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1775880:D3791 RS01670
gene id: 1775880:D3791_RS01670
uniprot id: A0A6H0SE72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1775880:D3791 RS08710
gene id: 1775880:D3791_RS08710
uniprot id: A0A6H0SJ91
names: Similarity
messages: Belongs to the peptidase C15 family.

1775880:D3791 RS11145
gene id: 1775880:D3791_RS11145
uniprot id: A0A6H0SKE4
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1775880:D3791 RS16245
gene id: 1775880:D3791_RS16245
uniprot id: A0A6H0SM47
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS13435
gene id: 1775880:D3791_RS13435
uniprot id: A0A6H0SN48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1775880:D3791 RS14380
gene id: 1775880:D3791_RS14380
uniprot id: A0A6H0SP21
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1775880:D3791 RS00940
gene id: 1775880:D3791_RS00940
uniprot id: A0A6H0SDT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1775880:D3791 RS05815
gene id: 1775880:D3791_RS05815
uniprot id: A0A6H0SJG2
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1775880:D3791 RS00080
gene id: 1775880:D3791_RS00080
uniprot id: A0A6H0SET8
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1775880:D3791 RS08610
gene id: 1775880:D3791_RS08610
uniprot id: A0A6H0SIF9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS14275
gene id: 1775880:D3791_RS14275
uniprot id: A0A6H0SNJ4
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS06330
gene id: 1775880:D3791_RS06330
uniprot id: A0A6H0SLC5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1775880:D3791 RS14460
gene id: 1775880:D3791_RS14460
uniprot id: A0A6H0SPC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1775880:D3791 RS07710
gene id: 1775880:D3791_RS07710
uniprot id: A0A6H0SIQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

1775880:D3791 RS00570
gene id: 1775880:D3791_RS00570
uniprot id: A0A6H0SHC7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1775880:D3791 RS02845
gene id: 1775880:D3791_RS02845
uniprot id: A0A6H0SG55
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

1775880:D3791 RS03940
gene id: 1775880:D3791_RS03940
uniprot id: A0A6H0SG34
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1775880:D3791 RS03005
gene id: 1775880:D3791_RS03005
uniprot id: A0A6H0SI08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1775880:D3791 RS06205
gene id: 1775880:D3791_RS06205
uniprot id: A0A6H0SHI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS02880
gene id: 1775880:D3791_RS02880
uniprot id: A0A6H0SJJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1775880:D3791 RS07445
gene id: 1775880:D3791_RS07445
uniprot id: A0A6H0SHJ7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1775880:D3791 RS12005
gene id: 1775880:D3791_RS12005
uniprot id: A0A6H0SP45
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1775880:D3791 RS16630
gene id: 1775880:D3791_RS16630
uniprot id: A0A6H0SMP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1775880:D3791 RS16500
gene id: 1775880:D3791_RS16500
uniprot id: A0A6H0SQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1775880:D3791 RS12435
gene id: 1775880:D3791_RS12435
uniprot id: A0A6H0SKI7
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS13300
gene id: 1775880:D3791_RS13300
uniprot id: A0A6H0SNH5
names: Similarity
messages: Belongs to the universal stress protein A family.

1775880:D3791 RS16605
gene id: 1775880:D3791_RS16605
uniprot id: A0A6H0SQ76
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS03115
gene id: 1775880:D3791_RS03115
uniprot id: A0A6H0SEY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1775880:D3791 RS14050
gene id: 1775880:D3791_RS14050
uniprot id: A0A6H0SK97
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1775880:D3791 RS14565
gene id: 1775880:D3791_RS14565
uniprot id: A0A6H0SLM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1775880:D3791 RS12670
gene id: 1775880:D3791_RS12670
uniprot id: A0A6H0SN67
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1775880:D3791 RS10255
gene id: 1775880:D3791_RS10255
uniprot id: A0A6H0SM13
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1775880:D3791 RS13100
gene id: 1775880:D3791_RS13100
uniprot id: A0A6H0SJS8
names: Similarity
messages: Belongs to the YciI family.

1775880:D3791 RS14160
gene id: 1775880:D3791_RS14160
uniprot id: A0A6H0SNH3
names: Similarity
messages: Belongs to the GSP E family.

1775880:D3791 RS05285
gene id: 1775880:D3791_RS05285
uniprot id: A0A6H0SG16
names: Similarity
messages: Belongs to the universal stress protein A family.

1775880:D3791 RS09250
gene id: 1775880:D3791_RS09250
uniprot id: A0A6H0SLX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1775880:D3791 RS13490
gene id: 1775880:D3791_RS13490
uniprot id: A0A6H0SN56
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1775880:D3791 RS04385
gene id: 1775880:D3791_RS04385
uniprot id: A0A6H0SGC1
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS14230
gene id: 1775880:D3791_RS14230
uniprot id: A0A6H0SLF3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1775880:D3791 RS07915
gene id: 1775880:D3791_RS07915
uniprot id: A0A6H0SHT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS11335
gene id: 1775880:D3791_RS11335
uniprot id: A0A6H0SJQ9
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS05685
gene id: 1775880:D3791_RS05685
uniprot id: A0A6H0SL01
names: Similarity
messages: Belongs to the DSD1 family.

1775880:D3791 RS03325
gene id: 1775880:D3791_RS03325
uniprot id: A0A6H0SFR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1775880:D3791 RS16595
gene id: 1775880:D3791_RS16595
uniprot id: A0A6H0SRH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1775880:D3791 RS01925
gene id: 1775880:D3791_RS01925
uniprot id: A0A6H0SFQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1775880:D3791 RS12945
gene id: 1775880:D3791_RS12945
uniprot id: A0A6H0SMY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1775880:D3791 RS00575
gene id: 1775880:D3791_RS00575
uniprot id: A0A6H0SF27
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1775880:D3791 RS15245
gene id: 1775880:D3791_RS15245
uniprot id: A0A6H0SKV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1775880:D3791 RS14255
gene id: 1775880:D3791_RS14255
uniprot id: A0A6H0SR27
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1775880:D3791 RS08130
gene id: 1775880:D3791_RS08130
uniprot id: A0A6H0SKK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1775880:D3791 RS16325
gene id: 1775880:D3791_RS16325
uniprot id: A0A6H0SN21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1775880:D3791 RS12155
gene id: 1775880:D3791_RS12155
uniprot id: A0A6H0SKD8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1775880:D3791 RS13665
gene id: 1775880:D3791_RS13665
uniprot id: A0A6H0SK26
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1775880:D3791 RS15850
gene id: 1775880:D3791_RS15850
uniprot id: A0A6H0SMB4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1775880:D3791 RS15035
gene id: 1775880:D3791_RS15035
uniprot id: A0A6H0SQP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1775880:D3791 RS07220
gene id: 1775880:D3791_RS07220
uniprot id: A0A6H0SHZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS02170
gene id: 1775880:D3791_RS02170
uniprot id: A0A6H0SFU6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1775880:D3791 RS09260
gene id: 1775880:D3791_RS09260
uniprot id: A0A6H0SMS1
names: Similarity
messages: Belongs to the UPF0045 family.

1775880:D3791 RS14475
gene id: 1775880:D3791_RS14475
uniprot id: A0A6H0SLC2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1775880:D3791 RS02230
gene id: 1775880:D3791_RS02230
uniprot id: A0A6H0SHL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1775880:D3791 RS06325
gene id: 1775880:D3791_RS06325
uniprot id: A0A6H0SI19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1775880:D3791 RS07800
gene id: 1775880:D3791_RS07800
uniprot id: A0A6H0SH97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1775880:D3791 RS02040
gene id: 1775880:D3791_RS02040
uniprot id: A0A6H0SHV1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1775880:D3791 RS05305
gene id: 1775880:D3791_RS05305
uniprot id: A0A6H0SHI3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1775880:D3791 RS05540
gene id: 1775880:D3791_RS05540
uniprot id: A0A6H0SHJ3
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS16320
gene id: 1775880:D3791_RS16320
uniprot id: A0A6H0SQA5
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1775880:D3791 RS05505
gene id: 1775880:D3791_RS05505
uniprot id: A0A6H0SGI0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1775880:D3791 RS07595
gene id: 1775880:D3791_RS07595
uniprot id: A0A6H0SKW5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1775880:D3791 RS01300
gene id: 1775880:D3791_RS01300
uniprot id: A0A6H0SE01
names: Similarity
messages: Belongs to the SufE family.

1775880:D3791 RS09660
gene id: 1775880:D3791_RS09660
uniprot id: A0A6H0SJ60
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1775880:D3791 RS11255
gene id: 1775880:D3791_RS11255
uniprot id: A0A6H0SJX8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1775880:D3791 RS13645
gene id: 1775880:D3791_RS13645
uniprot id: A0A6H0SNN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1775880:D3791 RS00910
gene id: 1775880:D3791_RS00910
uniprot id: A0A6H0SF86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1775880:D3791 RS03085
gene id: 1775880:D3791_RS03085
uniprot id: A0A6H0SJN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1775880:D3791 RS05050
gene id: 1775880:D3791_RS05050
uniprot id: A0A6H0SJ24
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS08280
gene id: 1775880:D3791_RS08280
uniprot id: A0A6H0SL27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1775880:D3791 RS11270
gene id: 1775880:D3791_RS11270
uniprot id: A0A6H0SKG4
names: Similarity
messages: Belongs to the peptidase C40 family.

1775880:D3791 RS12390
gene id: 1775880:D3791_RS12390
uniprot id: A0A6H0SPB6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1775880:D3791 RS08530
gene id: 1775880:D3791_RS08530
uniprot id: A0A6H0SI47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS03565
gene id: 1775880:D3791_RS03565
uniprot id: A0A6H0SFI7
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1775880:D3791 RS00495
gene id: 1775880:D3791_RS00495
uniprot id: A0A6H0SGR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1775880:D3791 RS15175
gene id: 1775880:D3791_RS15175
uniprot id: A0A6H0SLZ2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1775880:D3791 RS09000
gene id: 1775880:D3791_RS09000
uniprot id: A0A6H0SL08
names: Similarity
messages: Belongs to the AHA1 family.

1775880:D3791 RS04360
gene id: 1775880:D3791_RS04360
uniprot id: A0A6H0SJA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1775880:D3791 RS16345
gene id: 1775880:D3791_RS16345
uniprot id: A0A6H0SMY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1775880:D3791 RS14985
gene id: 1775880:D3791_RS14985
uniprot id: A0A6H0SQN7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1775880:D3791 RS00295
gene id: 1775880:D3791_RS00295
uniprot id: A0A6H0SGZ0
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

1775880:D3791 RS01305
gene id: 1775880:D3791_RS01305
uniprot id: A0A6H0SED9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1775880:D3791 RS02980
gene id: 1775880:D3791_RS02980
uniprot id: A0A6H0SGA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1775880:D3791 RS11495
gene id: 1775880:D3791_RS11495
uniprot id: A0A6H0SNV7
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1775880:D3791 RS16555
gene id: 1775880:D3791_RS16555
uniprot id: A0A6H0SQ67
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS00390
gene id: 1775880:D3791_RS00390
uniprot id: A0A6H0SH98
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1775880:D3791 RS01740
gene id: 1775880:D3791_RS01740
uniprot id: A0A6H0SRK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1775880:D3791 RS12335
gene id: 1775880:D3791_RS12335
uniprot id: A0A6H0SK94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1775880:D3791 RS14190
gene id: 1775880:D3791_RS14190
uniprot id: A0A6H0SQ95
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1775880:D3791 RS03255
gene id: 1775880:D3791_RS03255
uniprot id: A0A6H0SFQ9
names: Similarity
messages: Belongs to the UPF0336 family.

1775880:D3791 RS02905
gene id: 1775880:D3791_RS02905
uniprot id: A0A6H0SEU4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1775880:D3791 RS14340
gene id: 1775880:D3791_RS14340
uniprot id: A0A6H0SKE3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1775880:D3791 RS00250
gene id: 1775880:D3791_RS00250
uniprot id: A0A6H0SEW4
names: Subcellular Location Annotation
messages: Cytoplasm

1775880:D3791 RS13395
gene id: 1775880:D3791_RS13395
uniprot id: A0A6H0SL09
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS16250
gene id: 1775880:D3791_RS16250
uniprot id: A0A6H0SMI5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1775880:D3791 RS15190
gene id: 1775880:D3791_RS15190
uniprot id: A0A6H0SQS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1775880:D3791 RS05405
gene id: 1775880:D3791_RS05405
uniprot id: A0A6H0SH43
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1775880:D3791 RS15615
gene id: 1775880:D3791_RS15615
uniprot id: A0A6H0SLT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1775880:D3791 RS03785
gene id: 1775880:D3791_RS03785
uniprot id: A0A6H0SFA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1775880:D3791 RS03020
gene id: 1775880:D3791_RS03020
uniprot id: A0A6H0SFV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1775880:D3791 RS09995
gene id: 1775880:D3791_RS09995
uniprot id: A0A6H0SIB7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1775880:D3791 RS10805
gene id: 1775880:D3791_RS10805
uniprot id: A0A6H0SK62
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1775880:D3791 RS05325
gene id: 1775880:D3791_RS05325
uniprot id: A0A6H0SHF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS06040
gene id: 1775880:D3791_RS06040
uniprot id: A0A6H0SGU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS02935
gene id: 1775880:D3791_RS02935
uniprot id: A0A6H0SJK5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1775880:D3791 RS01580
gene id: 1775880:D3791_RS01580
uniprot id: A0A6H0SHV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1775880:D3791 RS01510
gene id: 1775880:D3791_RS01510
uniprot id: A0A6H0SH92
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1775880:D3791 RS02915
gene id: 1775880:D3791_RS02915
uniprot id: A0A6H0SFT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1775880:D3791 RS09590
gene id: 1775880:D3791_RS09590
uniprot id: A0A6H0SJJ3
names: Similarity
messages: Belongs to the TPP enzyme family.

1775880:D3791 RS02970
gene id: 1775880:D3791_RS02970
uniprot id: A0A6H0SFU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1775880:D3791 RS13260
gene id: 1775880:D3791_RS13260
uniprot id: A0A6H0SN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS15530
gene id: 1775880:D3791_RS15530
uniprot id: A0A6H0SMN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1775880:D3791 RS03070
gene id: 1775880:D3791_RS03070
uniprot id: A0A6H0SFW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1775880:D3791 RS03010
gene id: 1775880:D3791_RS03010
uniprot id: A0A6H0SEW5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1775880:D3791 RS05475
gene id: 1775880:D3791_RS05475
uniprot id: A0A6H0SKW1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1775880:D3791 RS12870
gene id: 1775880:D3791_RS12870
uniprot id: A0A6H0SKS2
names: Function
names: Similarity
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.
messages: Belongs to the IucA/IucC family.

1775880:D3791 RS14145
gene id: 1775880:D3791_RS14145
uniprot id: A0A6H0SL63
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1775880:D3791 RS13320
gene id: 1775880:D3791_RS13320
uniprot id: A0A6H0SQB0
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS16540
gene id: 1775880:D3791_RS16540
uniprot id: A0A6H0SN59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1775880:D3791 RS05080
gene id: 1775880:D3791_RS05080
uniprot id: A0A6H0SHE1
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS01130
gene id: 1775880:D3791_RS01130
uniprot id: A0A6H0SFC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1775880:D3791 RS16615
gene id: 1775880:D3791_RS16615
uniprot id: A0A6H0SPP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1775880:D3791 RS12760
gene id: 1775880:D3791_RS12760
uniprot id: A0A6H0SNI1
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1775880:D3791 RS14040
gene id: 1775880:D3791_RS14040
uniprot id: A0A6H0SLT4
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1775880:D3791 RS15780
gene id: 1775880:D3791_RS15780
uniprot id: A0A6H0SMN9
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1775880:D3791 RS01750
gene id: 1775880:D3791_RS01750
uniprot id: A0A6H0SIZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1775880:D3791 RS00505
gene id: 1775880:D3791_RS00505
uniprot id: A0A6H0SDY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1775880:D3791 RS12540
gene id: 1775880:D3791_RS12540
uniprot id: A0A6H0SK57
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1775880:D3791 RS02950
gene id: 1775880:D3791_RS02950
uniprot id: A0A6H0SG75
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1775880:D3791 RS08995
gene id: 1775880:D3791_RS08995
uniprot id: A0A6H0SJ95
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1775880:D3791 RS13115
gene id: 1775880:D3791_RS13115
uniprot id: A0A6H0SNN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1775880:D3791 RS03165
gene id: 1775880:D3791_RS03165
uniprot id: A0A6H0SI43
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS14665
gene id: 1775880:D3791_RS14665
uniprot id: A0A6H0SKK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS04170
gene id: 1775880:D3791_RS04170
uniprot id: A0A6H0SGU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1775880:D3791 RS13380
gene id: 1775880:D3791_RS13380
uniprot id: A0A6H0SJX9
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

1775880:D3791 RS13680
gene id: 1775880:D3791_RS13680
uniprot id: A0A6H0SNY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1775880:D3791 RS13710
gene id: 1775880:D3791_RS13710
uniprot id: A0A6H0SN95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1775880:D3791 RS01355
gene id: 1775880:D3791_RS01355
uniprot id: A0A6H0SH62
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1775880:D3791 RS04820
gene id: 1775880:D3791_RS04820
uniprot id: A0A6H0SH65
names: Similarity
messages: Belongs to the HIBADH-related family.

1775880:D3791 RS13720
gene id: 1775880:D3791_RS13720
uniprot id: A0A6H0SKS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1775880:D3791 RS14440
gene id: 1775880:D3791_RS14440
uniprot id: A0A6H0SNM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1775880:D3791 RS03025
gene id: 1775880:D3791_RS03025
uniprot id: A0A6H0SIM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1775880:D3791 RS02710
gene id: 1775880:D3791_RS02710
uniprot id: A0A6H0SJG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1775880:D3791 RS03585
gene id: 1775880:D3791_RS03585
uniprot id: A0A6H0SJX2
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS10800
gene id: 1775880:D3791_RS10800
uniprot id: A0A6H0SMA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1775880:D3791 RS04600
gene id: 1775880:D3791_RS04600
uniprot id: A0A6H0SGF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1775880:D3791 RS04645
gene id: 1775880:D3791_RS04645
uniprot id: A0A6H0SKH0
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS15600
gene id: 1775880:D3791_RS15600
uniprot id: A0A6H0SML1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1775880:D3791 RS16220
gene id: 1775880:D3791_RS16220
uniprot id: A0A6H0SM77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1775880:D3791 RS12915
gene id: 1775880:D3791_RS12915
uniprot id: A0A6H0SMV6
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS04475
gene id: 1775880:D3791_RS04475
uniprot id: A0A6H0SH28
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS02975
gene id: 1775880:D3791_RS02975
uniprot id: A0A6H0SIL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1775880:D3791 RS00445
gene id: 1775880:D3791_RS00445
uniprot id: A0A6H0SDX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1775880:D3791 RS06300
gene id: 1775880:D3791_RS06300
uniprot id: A0A6H0SJQ5
names: Similarity
messages: Belongs to the FemABX family.

1775880:D3791 RS09540
gene id: 1775880:D3791_RS09540
uniprot id: A0A6H0SJI1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1775880:D3791 RS14450
gene id: 1775880:D3791_RS14450
uniprot id: A0A6H0SL54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1775880:D3791 RS16150
gene id: 1775880:D3791_RS16150
uniprot id: A0A6H0SQ73
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS04150
gene id: 1775880:D3791_RS04150
uniprot id: A0A6H0SGW6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1775880:D3791 RS03365
gene id: 1775880:D3791_RS03365
uniprot id: A0A6H0SG13
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS12705
gene id: 1775880:D3791_RS12705
uniprot id: A0A6H0SQS1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1775880:D3791 RS11260
gene id: 1775880:D3791_RS11260
uniprot id: A0A6H0SMQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1775880:D3791 RS04195
gene id: 1775880:D3791_RS04195
uniprot id: A0A6H0SJ72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1775880:D3791 RS03120
gene id: 1775880:D3791_RS03120
uniprot id: A0A6H0SFA9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1775880:D3791 RS04175
gene id: 1775880:D3791_RS04175
uniprot id: A0A6H0SIL2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1775880:D3791 RS15315
gene id: 1775880:D3791_RS15315
uniprot id: A0A6H0SNT7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1775880:D3791 RS03420
gene id: 1775880:D3791_RS03420
uniprot id: A0A6H0SIT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS01505
gene id: 1775880:D3791_RS01505
uniprot id: A0A6H0SFI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1775880:D3791 RS00645
gene id: 1775880:D3791_RS00645
uniprot id: A0A6H0SF39
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1775880:D3791 RS03975
gene id: 1775880:D3791_RS03975
uniprot id: A0A6H0SJ38
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1775880:D3791 RS01875
gene id: 1775880:D3791_RS01875
uniprot id: A0A6H0SFP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS08380
gene id: 1775880:D3791_RS08380
uniprot id: A0A6H0SLB9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1775880:D3791 RS00930
gene id: 1775880:D3791_RS00930
uniprot id: A0A6H0SF84
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1775880:D3791 RS02210
gene id: 1775880:D3791_RS02210
uniprot id: A0A6H0SQJ0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1775880:D3791 RS01235
gene id: 1775880:D3791_RS01235
uniprot id: A0A6H0SIQ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1775880:D3791 RS12230
gene id: 1775880:D3791_RS12230
uniprot id: A0A6H0SKV9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1775880:D3791 RS03200
gene id: 1775880:D3791_RS03200
uniprot id: A0A6H0SFP9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1775880:D3791 RS16195
gene id: 1775880:D3791_RS16195
uniprot id: A0A6H0SM33
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1775880:D3791 RS06305
gene id: 1775880:D3791_RS06305
uniprot id: A0A6H0SGK5
names: Similarity
messages: Belongs to the CsoR family.

1775880:D3791 RS14385
gene id: 1775880:D3791_RS14385
uniprot id: A0A6H0SLZ0
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1775880:D3791 RS03050
gene id: 1775880:D3791_RS03050
uniprot id: A0A6H0SG95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1775880:D3791 RS02160
gene id: 1775880:D3791_RS02160
uniprot id: A0A6H0SF59
names: Similarity
messages: Belongs to the LOG family.

1775880:D3791 RS14045
gene id: 1775880:D3791_RS14045
uniprot id: A0A6H0SNF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1775880:D3791 RS12950
gene id: 1775880:D3791_RS12950
uniprot id: A0A6H0SLC1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS09335
gene id: 1775880:D3791_RS09335
uniprot id: A0A6H0SMT2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1775880:D3791 RS14540
gene id: 1775880:D3791_RS14540
uniprot id: A0A6H0SP51
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1775880:D3791 RS14135
gene id: 1775880:D3791_RS14135
uniprot id: A0A6H0SLX9
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1775880:D3791 RS13085
gene id: 1775880:D3791_RS13085
uniprot id: A0A6H0SND5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1775880:D3791 RS00830
gene id: 1775880:D3791_RS00830
uniprot id: A0A6H0SF66
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS12295
gene id: 1775880:D3791_RS12295
uniprot id: A0A6H0SMK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1775880:D3791 RS00125
gene id: 1775880:D3791_RS00125
uniprot id: A0A6H0SH49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1775880:D3791 RS03580
gene id: 1775880:D3791_RS03580
uniprot id: A0A6H0SGM0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1775880:D3791 RS09040
gene id: 1775880:D3791_RS09040
uniprot id: A0A6H0SIM9
names: Similarity
messages: Belongs to the CsoR family.

1775880:D3791 RS12015
gene id: 1775880:D3791_RS12015
uniprot id: A0A6H0SMV2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1775880:D3791 RS08135
gene id: 1775880:D3791_RS08135
uniprot id: A0A6H0SHF6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS16610
gene id: 1775880:D3791_RS16610
uniprot id: A0A6H0SN44
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1775880:D3791 RS13775
gene id: 1775880:D3791_RS13775
uniprot id: A0A6H0SL81
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1775880:D3791 RS09695
gene id: 1775880:D3791_RS09695
uniprot id: A0A6H0SLB6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1775880:D3791 RS00715
gene id: 1775880:D3791_RS00715
uniprot id: A0A6H0SF48
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1775880:D3791 RS09860
gene id: 1775880:D3791_RS09860
uniprot id: A0A6H0SJP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1775880:D3791 RS01855
gene id: 1775880:D3791_RS01855
uniprot id: A0A6H0SFQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS01680
gene id: 1775880:D3791_RS01680
uniprot id: A0A6H0SF63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1775880:D3791 RS01635
gene id: 1775880:D3791_RS01635
uniprot id: A0A6H0SFL5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1775880:D3791 RS01365
gene id: 1775880:D3791_RS01365
uniprot id: A0A6H0SEE9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1775880:D3791 RS05335
gene id: 1775880:D3791_RS05335
uniprot id: A0A6H0SG25
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1775880:D3791 RS13190
gene id: 1775880:D3791_RS13190
uniprot id: A0A6H0SNF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1775880:D3791 RS01710
gene id: 1775880:D3791_RS01710
uniprot id: A0A6H0SFL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS08595
gene id: 1775880:D3791_RS08595
uniprot id: A0A6H0SLG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1775880:D3791 RS05450
gene id: 1775880:D3791_RS05450
uniprot id: A0A6H0SG43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS03615
gene id: 1775880:D3791_RS03615
uniprot id: A0A6H0SFJ7
names: Subcellular Location Annotation
messages: Membrane

1775880:D3791 RS04650
gene id: 1775880:D3791_RS04650
uniprot id: A0A6H0SGG9
names: Subcellular Location Annotation
messages: Cytoplasm

1775880:D3791 RS04185
gene id: 1775880:D3791_RS04185
uniprot id: A0A6H0SFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS08715
gene id: 1775880:D3791_RS08715
uniprot id: A0A6H0SMI3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1775880:D3791 RS01985
gene id: 1775880:D3791_RS01985
uniprot id: A0A6H0SF32
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1775880:D3791 RS02985
gene id: 1775880:D3791_RS02985
uniprot id: A0A6H0SJL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1775880:D3791 RS06210
gene id: 1775880:D3791_RS06210
uniprot id: A0A6H0SK91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1775880:D3791 RS00030
gene id: 1775880:D3791_RS00030
uniprot id: A0A6H0SMP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1775880:D3791 RS03130
gene id: 1775880:D3791_RS03130
uniprot id: A0A6H0SIP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1775880:D3791 RS15775
gene id: 1775880:D3791_RS15775
uniprot id: A0A6H0SPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1775880:D3791 RS00050
gene id: 1775880:D3791_RS00050
uniprot id: A0A6H0SMF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1775880:D3791 RS13810
gene id: 1775880:D3791_RS13810
uniprot id: A0A6H0SNB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1775880:D3791 RS11925
gene id: 1775880:D3791_RS11925
uniprot id: A0A6H0SK93
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1775880:D3791 RS12860
gene id: 1775880:D3791_RS12860
uniprot id: A0A6H0SJP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1775880:D3791 RS11940
gene id: 1775880:D3791_RS11940
uniprot id: A0A6H0SP36
names: Similarity
messages: Belongs to the cytochrome b560 family.

1775880:D3791 RS13880
gene id: 1775880:D3791_RS13880
uniprot id: A0A6H0SKV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1775880:D3791 RS03110
gene id: 1775880:D3791_RS03110
uniprot id: A0A6H0SI33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1775880:D3791 RS00915
gene id: 1775880:D3791_RS00915
uniprot id: A0A6H0SII5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1775880:D3791 RS01650
gene id: 1775880:D3791_RS01650
uniprot id: A0A6H0SHN0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1775880:D3791 RS01630
gene id: 1775880:D3791_RS01630
uniprot id: A0A6H0SHW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1775880:D3791 RS12130
gene id: 1775880:D3791_RS12130
uniprot id: A0A6H0SMX0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1775880:D3791 RS15805
gene id: 1775880:D3791_RS15805
uniprot id: A0A6H0SQ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1775880:D3791 RS02025
gene id: 1775880:D3791_RS02025
uniprot id: A0A6H0SFT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1775880:D3791 RS07755
gene id: 1775880:D3791_RS07755
uniprot id: A0A6H0SI78
names: Subcellular Location Annotation
messages: Membrane