1750:EL272 RS03310
gene id: 1750:EL272_RS03310
uniprot id: A0A3N4CWQ7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1750:EL272 RS14015
gene id: 1750:EL272_RS14015
uniprot id: A0A448N2D4
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1750:EL272 RS06665
gene id: 1750:EL272_RS06665
uniprot id: A0A3N4D1V7
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS07945
gene id: 1750:EL272_RS07945
uniprot id: A0A448MYT8
names: Similarity
messages: Belongs to the fatty acyl-CoA reductase family.

1750:EL272 RS05240
gene id: 1750:EL272_RS05240
uniprot id: A0A3N4D2H6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS03115
gene id: 1750:EL272_RS03115
uniprot id: A0A3N4D5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1750:EL272 RS10845
gene id: 1750:EL272_RS10845
uniprot id: A0A3N4D945
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1750:EL272 RS10750
gene id: 1750:EL272_RS10750
uniprot id: A0A3N4D2K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1750:EL272 RS10920
gene id: 1750:EL272_RS10920
uniprot id: A0A3N4D2G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1750:EL272 RS03170
gene id: 1750:EL272_RS03170
uniprot id: A0A448MWA3
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS06785
gene id: 1750:EL272_RS06785
uniprot id: A0A4P8ZRH5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1750:EL272 RS07335
gene id: 1750:EL272_RS07335
uniprot id: A0A3N4DIW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1750:EL272 RS02890
gene id: 1750:EL272_RS02890
uniprot id: A0A3S4W5L5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1750:EL272 RS08065
gene id: 1750:EL272_RS08065
uniprot id: A0A3N4CTW4
names: Similarity
messages: Belongs to the TrpC family.

1750:EL272 RS03730
gene id: 1750:EL272_RS03730
uniprot id: A0A3S4W5W1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1750:EL272 RS10440
gene id: 1750:EL272_RS10440
uniprot id: A0A3N4D0N8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1750:EL272 RS07095
gene id: 1750:EL272_RS07095
uniprot id: A0A3N4CUC4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1750:EL272 RS10630
gene id: 1750:EL272_RS10630
uniprot id: A0A3N4D2M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1750:EL272 RS02095
gene id: 1750:EL272_RS02095
uniprot id: A0A3S4UD05
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1750:EL272 RS06835
gene id: 1750:EL272_RS06835
uniprot id: A0A3N4D1S9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1750:EL272 RS12635
gene id: 1750:EL272_RS12635
uniprot id: A0A3S4W8I2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1750:EL272 RS05205
gene id: 1750:EL272_RS05205
uniprot id: A0A3N4DK07
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1750:EL272 RS04045
gene id: 1750:EL272_RS04045
uniprot id: A0A3N4CY94
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1750:EL272 RS02285
gene id: 1750:EL272_RS02285
uniprot id: A0A3N4CWN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1750:EL272 RS13230
gene id: 1750:EL272_RS13230
uniprot id: A0A3N4DBZ1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1750:EL272 RS14230
gene id: 1750:EL272_RS14230
uniprot id: A0A3N4D010
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1750:EL272 RS09530
gene id: 1750:EL272_RS09530
uniprot id: A0A3S4U0Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1750:EL272 RS08980
gene id: 1750:EL272_RS08980
uniprot id: A0A3S5ESR0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1750:EL272 RS07795
gene id: 1750:EL272_RS07795
uniprot id: A0A3N4CVW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1750:EL272 RS11640
gene id: 1750:EL272_RS11640
uniprot id: A0A4P8ZSD6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1750:EL272 RS06235
gene id: 1750:EL272_RS06235
uniprot id: A0A3N4DJF5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1750:EL272 RS07800
gene id: 1750:EL272_RS07800
uniprot id: A0A448MYU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS04565
gene id: 1750:EL272_RS04565
uniprot id: A0A3S4Y687
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1750:EL272 RS06600
gene id: 1750:EL272_RS06600
uniprot id: A0A3N4D1W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS08735
gene id: 1750:EL272_RS08735
uniprot id: A0A448MZC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1750:EL272 RS01995
gene id: 1750:EL272_RS01995
uniprot id: A0A448MVE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

1750:EL272 RS05555
gene id: 1750:EL272_RS05555
uniprot id: A0A3N4CV12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1750:EL272 RS13350
gene id: 1750:EL272_RS13350
uniprot id: A0A3S4VKV9
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS13025
gene id: 1750:EL272_RS13025
uniprot id: A0A3S4VKR9
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS10605
gene id: 1750:EL272_RS10605
uniprot id: A0A3S5BBK5
names: Similarity
messages: Belongs to the YciI family.

1750:EL272 RS09895
gene id: 1750:EL272_RS09895
uniprot id: A0A3S4UD88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1750:EL272 RS14990
gene id: 1750:EL272_RS14990
uniprot id: A0A448N2S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1750:EL272 RS01290
gene id: 1750:EL272_RS01290
uniprot id: A0A3N4CXB3
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS04440
gene id: 1750:EL272_RS04440
uniprot id: A0A448MX16
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1750:EL272 RS02960
gene id: 1750:EL272_RS02960
uniprot id: A0A3N4CWA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS12260
gene id: 1750:EL272_RS12260
uniprot id: A0A3S4W8E9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1750:EL272 RS14640
gene id: 1750:EL272_RS14640
uniprot id: A0A3N4D221
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1750:EL272 RS06645
gene id: 1750:EL272_RS06645
uniprot id: A0A3N4D3Z1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1750:EL272 RS08410
gene id: 1750:EL272_RS08410
uniprot id: A0A3N4CUG1
names: Similarity
messages: Belongs to the UPF0371 family.

1750:EL272 RS01490
gene id: 1750:EL272_RS01490
uniprot id: A0A3S5ESH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS09810
gene id: 1750:EL272_RS09810
uniprot id: A0A3S4Y7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1750:EL272 RS09605
gene id: 1750:EL272_RS09605
uniprot id: A0A448MZU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1750:EL272 RS03320
gene id: 1750:EL272_RS03320
uniprot id: A0A448MWD3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1750:EL272 RS04980
gene id: 1750:EL272_RS04980
uniprot id: A0A3N4D8U1
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS04335
gene id: 1750:EL272_RS04335
uniprot id: A0A3N4D338
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1750:EL272 RS00855
gene id: 1750:EL272_RS00855
uniprot id: A0A3S4Y547
names: Similarity
messages: Belongs to the hyi family.

1750:EL272 RS13780
gene id: 1750:EL272_RS13780
uniprot id: A0A3S4VL03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1750:EL272 RS07325
gene id: 1750:EL272_RS07325
uniprot id: A0A3S4W718
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1750:EL272 RS01775
gene id: 1750:EL272_RS01775
uniprot id: A0A3S5C5T2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1750:EL272 RS01345
gene id: 1750:EL272_RS01345
uniprot id: A0A3S4U3P5
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS11005
gene id: 1750:EL272_RS11005
uniprot id: A0A3N4D3X1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1750:EL272 RS09215
gene id: 1750:EL272_RS09215
uniprot id: A0A4P8ZWG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1750:EL272 RS13380
gene id: 1750:EL272_RS13380
uniprot id: A0A3S4W8Q4
names: Similarity
messages: Belongs to the thioesterase family.

1750:EL272 RS06695
gene id: 1750:EL272_RS06695
uniprot id: A0A3N4CV69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1750:EL272 RS10340
gene id: 1750:EL272_RS10340
uniprot id: A0A3N4D0T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS12865
gene id: 1750:EL272_RS12865
uniprot id: A0A3S4W8K0
names: Similarity
messages: Belongs to the fructosamine kinase family.

1750:EL272 RS13765
gene id: 1750:EL272_RS13765
uniprot id: A0A3S4U7X1
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS05135
gene id: 1750:EL272_RS05135
uniprot id: A0A448MXB7
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS08775
gene id: 1750:EL272_RS08775
uniprot id: A0A3N4D1J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1750:EL272 RS15170
gene id: 1750:EL272_RS15170
uniprot id: A0A3N4CXX6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1750:EL272 RS07975
gene id: 1750:EL272_RS07975
uniprot id: A0A3N4D7G4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1750:EL272 RS05525
gene id: 1750:EL272_RS05525
uniprot id: A0A4P8ZU11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS10595
gene id: 1750:EL272_RS10595
uniprot id: A0A3N4D790
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1750:EL272 RS05235
gene id: 1750:EL272_RS05235
uniprot id: A0A3N4CX16
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1750:EL272 RS14580
gene id: 1750:EL272_RS14580
uniprot id: A0A3N4CYF9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1750:EL272 RS01725
gene id: 1750:EL272_RS01725
uniprot id: A0A3S4Y5D3
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

1750:EL272 RS08585
gene id: 1750:EL272_RS08585
uniprot id: A0A448MZ98
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1750:EL272 RS14030
gene id: 1750:EL272_RS14030
uniprot id: A0A3N4D0Z7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1750:EL272 RS07900
gene id: 1750:EL272_RS07900
uniprot id: A0A4P8ZU83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1750:EL272 RS01380
gene id: 1750:EL272_RS01380
uniprot id: A0A3N4D6W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1750:EL272 RS09100
gene id: 1750:EL272_RS09100
uniprot id: A0A3S4UD07
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1750:EL272 RS14750
gene id: 1750:EL272_RS14750
uniprot id: A0A3S4Y0R4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1750:EL272 RS10810
gene id: 1750:EL272_RS10810
uniprot id: A0A3N4DA00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1750:EL272 RS06045
gene id: 1750:EL272_RS06045
uniprot id: A0A3N4CWN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1750:EL272 RS01385
gene id: 1750:EL272_RS01385
uniprot id: A0A448MV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1750:EL272 RS06065
gene id: 1750:EL272_RS06065
uniprot id: A0A3N4CVG7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1750:EL272 RS09185
gene id: 1750:EL272_RS09185
uniprot id: A0A3N4D4U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1750:EL272 RS08700
gene id: 1750:EL272_RS08700
uniprot id: A0A3N4DEA3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1750:EL272 RS11205
gene id: 1750:EL272_RS11205
uniprot id: A0A3S4U1H6
names: Similarity
messages: Belongs to the thioesterase family.

1750:EL272 RS11455
gene id: 1750:EL272_RS11455
uniprot id: A0A3N4DCY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1750:EL272 RS08720
gene id: 1750:EL272_RS08720
uniprot id: A0A3N4D1M3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1750:EL272 RS11800
gene id: 1750:EL272_RS11800
uniprot id: A0A448N109
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS13720
gene id: 1750:EL272_RS13720
uniprot id: A0A448N205
names: Similarity
messages: Belongs to the HsdR family.

1750:EL272 RS15065
gene id: 1750:EL272_RS15065
uniprot id: A0A3N4CY01
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1750:EL272 RS08185
gene id: 1750:EL272_RS08185
uniprot id: A0A448MZ21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1750:EL272 RS08170
gene id: 1750:EL272_RS08170
uniprot id: A0A3S4ZAM7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1750:EL272 RS10965
gene id: 1750:EL272_RS10965
uniprot id: A0A3S4VK53
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS04185
gene id: 1750:EL272_RS04185
uniprot id: A0A3N4CWA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1750:EL272 RS10935
gene id: 1750:EL272_RS10935
uniprot id: A0A3S4U6V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1750:EL272 RS10565
gene id: 1750:EL272_RS10565
uniprot id: A0A3N4DQ49
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1750:EL272 RS04890
gene id: 1750:EL272_RS04890
uniprot id: A0A3S4UTW2
names: Similarity
messages: Belongs to the asparaginase 1 family.

1750:EL272 RS14530
gene id: 1750:EL272_RS14530
uniprot id: A0A3S5ESX1
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS13420
gene id: 1750:EL272_RS13420
uniprot id: A0A3S5ESV9
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS06510
gene id: 1750:EL272_RS06510
uniprot id: A0A4V1GCB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1750:EL272 RS13640
gene id: 1750:EL272_RS13640
uniprot id: A0A448N238
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1750:EL272 RS05080
gene id: 1750:EL272_RS05080
uniprot id: A0A448MX95
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1750:EL272 RS07915
gene id: 1750:EL272_RS07915
uniprot id: A0A3N4D7H4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1750:EL272 RS09695
gene id: 1750:EL272_RS09695
uniprot id: A0A448N015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1750:EL272 RS13090
gene id: 1750:EL272_RS13090
uniprot id: A0A3S4UGV6
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09635
gene id: 1750:EL272_RS09635
uniprot id: A0A448MZS4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1750:EL272 RS08940
gene id: 1750:EL272_RS08940
uniprot id: A0A3N4D846
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1750:EL272 RS05570
gene id: 1750:EL272_RS05570
uniprot id: A0A3S4VIK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1750:EL272 RS01600
gene id: 1750:EL272_RS01600
uniprot id: A0A448MV97
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1750:EL272 RS02160
gene id: 1750:EL272_RS02160
uniprot id: A0A3N4CWW7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1750:EL272 RS06555
gene id: 1750:EL272_RS06555
uniprot id: A0A3N4CUL3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1750:EL272 RS03270
gene id: 1750:EL272_RS03270
uniprot id: A0A3S4UDD3
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS11445
gene id: 1750:EL272_RS11445
uniprot id: A0A3N4D297
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1750:EL272 RS02035
gene id: 1750:EL272_RS02035
uniprot id: A0A3N4CYM7
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1750:EL272 RS06700
gene id: 1750:EL272_RS06700
uniprot id: A0A3N4DJ64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1750:EL272 RS06185
gene id: 1750:EL272_RS06185
uniprot id: A0A448MXX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1750:EL272 RS06080
gene id: 1750:EL272_RS06080
uniprot id: A0A3N4CX53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1750:EL272 RS04785
gene id: 1750:EL272_RS04785
uniprot id: A0A3S4UDV2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1750:EL272 RS05280
gene id: 1750:EL272_RS05280
uniprot id: A0A4P8ZRK8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1750:EL272 RS11855
gene id: 1750:EL272_RS11855
uniprot id: A0A3S4UGF2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1750:EL272 RS03735
gene id: 1750:EL272_RS03735
uniprot id: A0A3S4TZ21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1750:EL272 RS08975
gene id: 1750:EL272_RS08975
uniprot id: A0A3S4Y7P2
names: Cofactor
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1750:EL272 RS12065
gene id: 1750:EL272_RS12065
uniprot id: A0A3N4D3F9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1750:EL272 RS05030
gene id: 1750:EL272_RS05030
uniprot id: A0A448MX86
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS02485
gene id: 1750:EL272_RS02485
uniprot id: A0A448MVQ8
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS05955
gene id: 1750:EL272_RS05955
uniprot id: A0A3N4CUX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1750:EL272 RS15720
gene id: 1750:EL272_RS15720
uniprot id: A0A4P8ZQN5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1750:EL272 RS06040
gene id: 1750:EL272_RS06040
uniprot id: A0A3N4D8C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1750:EL272 RS12595
gene id: 1750:EL272_RS12595
uniprot id: A0A3N4D924
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1750:EL272 RS10980
gene id: 1750:EL272_RS10980
uniprot id: A0A3N4D2F6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1750:EL272 RS07790
gene id: 1750:EL272_RS07790
uniprot id: A0A3N4D7J5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1750:EL272 RS08550
gene id: 1750:EL272_RS08550
uniprot id: A0A448MZF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1750:EL272 RS10495
gene id: 1750:EL272_RS10495
uniprot id: A0A3S4U6P7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS09335
gene id: 1750:EL272_RS09335
uniprot id: A0A3S5ESR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS09085
gene id: 1750:EL272_RS09085
uniprot id: A0A448MZF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1750:EL272 RS06165
gene id: 1750:EL272_RS06165
uniprot id: A0A3N4CUS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1750:EL272 RS00075
gene id: 1750:EL272_RS00075
uniprot id: A0A3S4UCG0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1750:EL272 RS11610
gene id: 1750:EL272_RS11610
uniprot id: A0A3S5EST9
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS02645
gene id: 1750:EL272_RS02645
uniprot id: A0A448MVT7
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS04460
gene id: 1750:EL272_RS04460
uniprot id: A0A3N4D8P7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1750:EL272 RS01225
gene id: 1750:EL272_RS01225
uniprot id: A0A448MV20
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09415
gene id: 1750:EL272_RS09415
uniprot id: A0A3S5ESR5
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS01280
gene id: 1750:EL272_RS01280
uniprot id: A0A448MV25
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1750:EL272 RS04530
gene id: 1750:EL272_RS04530
uniprot id: A0A448MWW6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1750:EL272 RS07040
gene id: 1750:EL272_RS07040
uniprot id: A0A3N4CV21
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1750:EL272 RS08710
gene id: 1750:EL272_RS08710
uniprot id: A0A448MZI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1750:EL272 RS00145
gene id: 1750:EL272_RS00145
uniprot id: A0A3N4DB38
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1750:EL272 RS06780
gene id: 1750:EL272_RS06780
uniprot id: A0A3N4D1T8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1750:EL272 RS07495
gene id: 1750:EL272_RS07495
uniprot id: A0A3S4VJ65
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1750:EL272 RS15105
gene id: 1750:EL272_RS15105
uniprot id: A0A3N4CYC4
names: Similarity
messages: Belongs to the thioredoxin family.

1750:EL272 RS08625
gene id: 1750:EL272_RS08625
uniprot id: A0A3S4W7F3
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1750:EL272 RS03200
gene id: 1750:EL272_RS03200
uniprot id: A0A448MW62
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1750:EL272 RS04970
gene id: 1750:EL272_RS04970
uniprot id: A0A448MX47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1750:EL272 RS02825
gene id: 1750:EL272_RS02825
uniprot id: A0A3N4D4D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

1750:EL272 RS06325
gene id: 1750:EL272_RS06325
uniprot id: A0A3N4CWJ6
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1750:EL272 RS05990
gene id: 1750:EL272_RS05990
uniprot id: A0A3N4D8D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1750:EL272 RS12750
gene id: 1750:EL272_RS12750
uniprot id: A0A3S4ZC04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS08695
gene id: 1750:EL272_RS08695
uniprot id: A0A3S4UFE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1750:EL272 RS11095
gene id: 1750:EL272_RS11095
uniprot id: A0A3N4D0A9
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1750:EL272 RS06640
gene id: 1750:EL272_RS06640
uniprot id: A0A3N4CWU2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS11030
gene id: 1750:EL272_RS11030
uniprot id: A0A3N4D0E2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1750:EL272 RS07680
gene id: 1750:EL272_RS07680
uniprot id: A0A3S4W758
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1750:EL272 RS02470
gene id: 1750:EL272_RS02470
uniprot id: A0A3N4CYD8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1750:EL272 RS10625
gene id: 1750:EL272_RS10625
uniprot id: A0A4P8ZRP6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1750:EL272 RS10165
gene id: 1750:EL272_RS10165
uniprot id: A0A3N4D0W8
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS11480
gene id: 1750:EL272_RS11480
uniprot id: A0A3N4D039
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1750:EL272 RS05220
gene id: 1750:EL272_RS05220
uniprot id: A0A4P8ZXG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1750:EL272 RS02240
gene id: 1750:EL272_RS02240
uniprot id: A0A3S4Y5I2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1750:EL272 RS10085
gene id: 1750:EL272_RS10085
uniprot id: A0A4P8ZRG4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1750:EL272 RS05980
gene id: 1750:EL272_RS05980
uniprot id: A0A3N4CX80
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1750:EL272 RS03860
gene id: 1750:EL272_RS03860
uniprot id: A0A3S4Y606
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS05040
gene id: 1750:EL272_RS05040
uniprot id: A0A3N4CXR7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1750:EL272 RS11620
gene id: 1750:EL272_RS11620
uniprot id: A0A3S4UDS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS12715
gene id: 1750:EL272_RS12715
uniprot id: A0A3S4Y064
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1750:EL272 RS04060
gene id: 1750:EL272_RS04060
uniprot id: A0A448MWM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1750:EL272 RS07220
gene id: 1750:EL272_RS07220
uniprot id: A0A448MYD6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1750:EL272 RS04010
gene id: 1750:EL272_RS04010
uniprot id: A0A3S4UBF5
names: Similarity
messages: Belongs to the GSP E family.

1750:EL272 RS10295
gene id: 1750:EL272_RS10295
uniprot id: A0A3S4UDC2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1750:EL272 RS10305
gene id: 1750:EL272_RS10305
uniprot id: A0A3N4D7E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1750:EL272 RS09980
gene id: 1750:EL272_RS09980
uniprot id: A0A3N4D4H0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS04745
gene id: 1750:EL272_RS04745
uniprot id: A0A448MWZ4
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS12730
gene id: 1750:EL272_RS12730
uniprot id: A0A448N1P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1750:EL272 RS06750
gene id: 1750:EL272_RS06750
uniprot id: A0A448MY80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1750:EL272 RS11555
gene id: 1750:EL272_RS11555
uniprot id: A0A3S4W875
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1750:EL272 RS05330
gene id: 1750:EL272_RS05330
uniprot id: A0A3S4Y6G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1750:EL272 RS09710
gene id: 1750:EL272_RS09710
uniprot id: A0A3N4D4L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1750:EL272 RS06965
gene id: 1750:EL272_RS06965
uniprot id: A0A448MY96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1750:EL272 RS05265
gene id: 1750:EL272_RS05265
uniprot id: A0A3S4U4Y0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1750:EL272 RS00965
gene id: 1750:EL272_RS00965
uniprot id: A0A3S4ZHU6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1750:EL272 RS07215
gene id: 1750:EL272_RS07215
uniprot id: A0A4P8ZSE9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1750:EL272 RS13035
gene id: 1750:EL272_RS13035
uniprot id: A0A3N4DC25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1750:EL272 RS10655
gene id: 1750:EL272_RS10655
uniprot id: A0A3N4D432
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1750:EL272 RS14820
gene id: 1750:EL272_RS14820
uniprot id: A0A3N4CYH6
names: Similarity
messages: Belongs to the FemABX family.

1750:EL272 RS11440
gene id: 1750:EL272_RS11440
uniprot id: A0A3N4D056
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1750:EL272 RS12220
gene id: 1750:EL272_RS12220
uniprot id: A0A3N4D0Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS02260
gene id: 1750:EL272_RS02260
uniprot id: A0A3S4U3Z7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1750:EL272 RS12040
gene id: 1750:EL272_RS12040
uniprot id: A0A3S4UVY4
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1750:EL272 RS06975
gene id: 1750:EL272_RS06975
uniprot id: A0A3S4Y700
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1750:EL272 RS04840
gene id: 1750:EL272_RS04840
uniprot id: A0A3S4U4S8
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1750:EL272 RS00055
gene id: 1750:EL272_RS00055
uniprot id: A0A3S4VGY6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1750:EL272 RS11870
gene id: 1750:EL272_RS11870
uniprot id: A0A3N4D233
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1750:EL272 RS09140
gene id: 1750:EL272_RS09140
uniprot id: A0A3N4D1D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1750:EL272 RS08215
gene id: 1750:EL272_RS08215
uniprot id: A0A3S4YYH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1750:EL272 RS10840
gene id: 1750:EL272_RS10840
uniprot id: A0A3N4D0C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1750:EL272 RS05840
gene id: 1750:EL272_RS05840
uniprot id: A0A3N4DJM0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1750:EL272 RS07415
gene id: 1750:EL272_RS07415
uniprot id: A0A3N4CU66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1750:EL272 RS09170
gene id: 1750:EL272_RS09170
uniprot id: A0A3S4UD17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS00410
gene id: 1750:EL272_RS00410
uniprot id: A0A3S4U3E1
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS11660
gene id: 1750:EL272_RS11660
uniprot id: A0A3S4UGD2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS10830
gene id: 1750:EL272_RS10830
uniprot id: A0A3N4D402
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1750:EL272 RS01460
gene id: 1750:EL272_RS01460
uniprot id: A0A3N4D4K6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1750:EL272 RS09060
gene id: 1750:EL272_RS09060
uniprot id: A0A3N4D823
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1750:EL272 RS03180
gene id: 1750:EL272_RS03180
uniprot id: A0A3N4CY20
names: Similarity
messages: Belongs to the universal stress protein A family.

1750:EL272 RS05480
gene id: 1750:EL272_RS05480
uniprot id: A0A3S4UE52
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1750:EL272 RS01850
gene id: 1750:EL272_RS01850
uniprot id: A0A3S4ZR01
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09130
gene id: 1750:EL272_RS09130
uniprot id: A0A3N4D4V1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1750:EL272 RS05930
gene id: 1750:EL272_RS05930
uniprot id: A0A4P8ZV02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1750:EL272 RS11485
gene id: 1750:EL272_RS11485
uniprot id: A0A4P8ZTL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1750:EL272 RS00010
gene id: 1750:EL272_RS00010
uniprot id: A0A3S4USH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1750:EL272 RS07445
gene id: 1750:EL272_RS07445
uniprot id: A0A3S4UEV6
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS14965
gene id: 1750:EL272_RS14965
uniprot id: A0A3N4D1W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1750:EL272 RS02270
gene id: 1750:EL272_RS02270
uniprot id: A0A448MVL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1750:EL272 RS03985
gene id: 1750:EL272_RS03985
uniprot id: A0A3S4TZ48
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS10925
gene id: 1750:EL272_RS10925
uniprot id: A0A3N4D9Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1750:EL272 RS04510
gene id: 1750:EL272_RS04510
uniprot id: A0A3N4CVI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1750:EL272 RS06710
gene id: 1750:EL272_RS06710
uniprot id: A0A3N4CWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1750:EL272 RS02065
gene id: 1750:EL272_RS02065
uniprot id: A0A3N4CWS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

1750:EL272 RS10880
gene id: 1750:EL272_RS10880
uniprot id: A0A3S4VK41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1750:EL272 RS03120
gene id: 1750:EL272_RS03120
uniprot id: A0A3N4D4C8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1750:EL272 RS10650
gene id: 1750:EL272_RS10650
uniprot id: A0A3N4D782
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1750:EL272 RS11960
gene id: 1750:EL272_RS11960
uniprot id: A0A3S4U1Q5
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09120
gene id: 1750:EL272_RS09120
uniprot id: A0A4V1GCF7
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1750:EL272 RS12415
gene id: 1750:EL272_RS12415
uniprot id: A0A3N4D6H8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1750:EL272 RS08245
gene id: 1750:EL272_RS08245
uniprot id: A0A3S4U0M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1750:EL272 RS02155
gene id: 1750:EL272_RS02155
uniprot id: A0A4V1GC34
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1750:EL272 RS08285
gene id: 1750:EL272_RS08285
uniprot id: A0A3S4U5Z5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS01570
gene id: 1750:EL272_RS01570
uniprot id: A0A3N4D128
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1750:EL272 RS07785
gene id: 1750:EL272_RS07785
uniprot id: A0A3N4D398
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1750:EL272 RS09210
gene id: 1750:EL272_RS09210
uniprot id: A0A448MZK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1750:EL272 RS07160
gene id: 1750:EL272_RS07160
uniprot id: A0A3N4CV07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1750:EL272 RS10095
gene id: 1750:EL272_RS10095
uniprot id: A0A3N4D0S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1750:EL272 RS08765
gene id: 1750:EL272_RS08765
uniprot id: A0A3S4Y7L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1750:EL272 RS11050
gene id: 1750:EL272_RS11050
uniprot id: A0A448N0S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1750:EL272 RS10245
gene id: 1750:EL272_RS10245
uniprot id: A0A3N4D1Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1750:EL272 RS15140
gene id: 1750:EL272_RS15140
uniprot id: A0A3N4D591
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1750:EL272 RS10490
gene id: 1750:EL272_RS10490
uniprot id: A0A448N0B8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS10800
gene id: 1750:EL272_RS10800
uniprot id: A0A3N4D0I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1750:EL272 RS07240
gene id: 1750:EL272_RS07240
uniprot id: A0A3N4CWI8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1750:EL272 RS06770
gene id: 1750:EL272_RS06770
uniprot id: A0A4P8ZQ16
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1750:EL272 RS08110
gene id: 1750:EL272_RS08110
uniprot id: A0A3S4U5X2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1750:EL272 RS06635
gene id: 1750:EL272_RS06635
uniprot id: A0A3S4U019
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1750:EL272 RS03040
gene id: 1750:EL272_RS03040
uniprot id: A0A3S4TYU4
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

1750:EL272 RS02975
gene id: 1750:EL272_RS02975
uniprot id: A0A3N4D9U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1750:EL272 RS01465
gene id: 1750:EL272_RS01465
uniprot id: A0A448MV78
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1750:EL272 RS01285
gene id: 1750:EL272_RS01285
uniprot id: A0A3N4DC31
names: Similarity
messages: Belongs to the CsoR family.

1750:EL272 RS11240
gene id: 1750:EL272_RS11240
uniprot id: A0A3N4D1F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1750:EL272 RS10150
gene id: 1750:EL272_RS10150
uniprot id: A0A3S4U158
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS02315
gene id: 1750:EL272_RS02315
uniprot id: A0A3S4W5G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1750:EL272 RS07530
gene id: 1750:EL272_RS07530
uniprot id: A0A448MYM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1750:EL272 RS13825
gene id: 1750:EL272_RS13825
uniprot id: A0A3S4U2A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1750:EL272 RS07270
gene id: 1750:EL272_RS07270
uniprot id: A0A3N4CY69
names: Similarity
messages: Belongs to the thymidine kinase family.

1750:EL272 RS09520
gene id: 1750:EL272_RS09520
uniprot id: A0A3S4UFN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1750:EL272 RS11535
gene id: 1750:EL272_RS11535
uniprot id: A0A3S4U767
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1750:EL272 RS04420
gene id: 1750:EL272_RS04420
uniprot id: A0A448MWU3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS08405
gene id: 1750:EL272_RS08405
uniprot id: A0A3N4CTR2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1750:EL272 RS09990
gene id: 1750:EL272_RS09990
uniprot id: A0A3N4D0W5
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

1750:EL272 RS06320
gene id: 1750:EL272_RS06320
uniprot id: A0A3N4D866
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS08850
gene id: 1750:EL272_RS08850
uniprot id: A0A448MZ92
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1750:EL272 RS12670
gene id: 1750:EL272_RS12670
uniprot id: A0A3S5ESV1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1750:EL272 RS10805
gene id: 1750:EL272_RS10805
uniprot id: A0A3N4D2J3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1750:EL272 RS14010
gene id: 1750:EL272_RS14010
uniprot id: A0A3S4UEL6
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS13995
gene id: 1750:EL272_RS13995
uniprot id: A0A3N4D5T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS06845
gene id: 1750:EL272_RS06845
uniprot id: A0A3S4UUH1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1750:EL272 RS15005
gene id: 1750:EL272_RS15005
uniprot id: A0A3S5ESX6
names: Similarity
messages: Belongs to the Dps family.

1750:EL272 RS01910
gene id: 1750:EL272_RS01910
uniprot id: A0A448MVH3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1750:EL272 RS11170
gene id: 1750:EL272_RS11170
uniprot id: A0A3S5EST4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1750:EL272 RS13815
gene id: 1750:EL272_RS13815
uniprot id: A0A3N4CYT9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1750:EL272 RS07700
gene id: 1750:EL272_RS07700
uniprot id: A0A3S4UUQ4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1750:EL272 RS02810
gene id: 1750:EL272_RS02810
uniprot id: A0A3S4UT97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1750:EL272 RS06300
gene id: 1750:EL272_RS06300
uniprot id: A0A3N4DJE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1750:EL272 RS07775
gene id: 1750:EL272_RS07775
uniprot id: A0A3N4CU16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1750:EL272 RS10275
gene id: 1750:EL272_RS10275
uniprot id: A0A3N4DQC3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1750:EL272 RS13770
gene id: 1750:EL272_RS13770
uniprot id: A0A448N268
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS08300
gene id: 1750:EL272_RS08300
uniprot id: A0A448MZ41
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1750:EL272 RS05000
gene id: 1750:EL272_RS05000
uniprot id: A0A3S5ESL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1750:EL272 RS11460
gene id: 1750:EL272_RS11460
uniprot id: A0A3N4D1B0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1750:EL272 RS14040
gene id: 1750:EL272_RS14040
uniprot id: A0A3N4DBP2
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS09150
gene id: 1750:EL272_RS09150
uniprot id: A0A4P8ZU76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1750:EL272 RS09725
gene id: 1750:EL272_RS09725
uniprot id: A0A448MZR9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS06650
gene id: 1750:EL272_RS06650
uniprot id: A0A3N4D819
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1750:EL272 RS05755
gene id: 1750:EL272_RS05755
uniprot id: A0A448MXJ4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1750:EL272 RS12770
gene id: 1750:EL272_RS12770
uniprot id: A0A3S4Y8U0
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS12590
gene id: 1750:EL272_RS12590
uniprot id: A0A3S4Y8S1
names: Similarity
messages: Belongs to the YoeB family.

1750:EL272 RS10620
gene id: 1750:EL272_RS10620
uniprot id: A0A3N4DQ40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1750:EL272 RS02400
gene id: 1750:EL272_RS02400
uniprot id: A0A448MVU0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1750:EL272 RS08015
gene id: 1750:EL272_RS08015
uniprot id: A0A3S4XYW9
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS10640
gene id: 1750:EL272_RS10640
uniprot id: A0A3N4DD97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1750:EL272 RS08745
gene id: 1750:EL272_RS08745
uniprot id: A0A448MZ97
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1750:EL272 RS05620
gene id: 1750:EL272_RS05620
uniprot id: A0A3N4CXF5
names: Similarity
messages: Belongs to the peptidase M24B family.

1750:EL272 RS06050
gene id: 1750:EL272_RS06050
uniprot id: A0A3S5ESM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1750:EL272 RS13440
gene id: 1750:EL272_RS13440
uniprot id: A0A448N1Y4
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS08480
gene id: 1750:EL272_RS08480
uniprot id: A0A4P8ZU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1750:EL272 RS03880
gene id: 1750:EL272_RS03880
uniprot id: A0A448MWQ5
names: Similarity
messages: Belongs to the urocanase family.

1750:EL272 RS01230
gene id: 1750:EL272_RS01230
uniprot id: A0A448MV11
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1750:EL272 RS10210
gene id: 1750:EL272_RS10210
uniprot id: A0A3S4VJY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS11420
gene id: 1750:EL272_RS11420
uniprot id: A0A3N4D049
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1750:EL272 RS12930
gene id: 1750:EL272_RS12930
uniprot id: A0A3S4U7M6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1750:EL272 RS07805
gene id: 1750:EL272_RS07805
uniprot id: A0A448MYT7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1750:EL272 RS12990
gene id: 1750:EL272_RS12990
uniprot id: A0A3S4YZV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1750:EL272 RS08925
gene id: 1750:EL272_RS08925
uniprot id: A0A448MZM1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1750:EL272 RS04495
gene id: 1750:EL272_RS04495
uniprot id: A0A448MWW0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1750:EL272 RS03790
gene id: 1750:EL272_RS03790
uniprot id: A0A3S4U4H3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1750:EL272 RS06540
gene id: 1750:EL272_RS06540
uniprot id: A0A4P8ZWA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS10350
gene id: 1750:EL272_RS10350
uniprot id: A0A3N4DAA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1750:EL272 RS11805
gene id: 1750:EL272_RS11805
uniprot id: A0A3N4DPI8
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS03645
gene id: 1750:EL272_RS03645
uniprot id: A0A3S4VHZ1
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1750:EL272 RS06705
gene id: 1750:EL272_RS06705
uniprot id: A0A3N4CUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1750:EL272 RS13225
gene id: 1750:EL272_RS13225
uniprot id: A0A3N4D8H6
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS05255
gene id: 1750:EL272_RS05255
uniprot id: A0A3N4CV72
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1750:EL272 RS07405
gene id: 1750:EL272_RS07405
uniprot id: A0A448MYE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1750:EL272 RS14620
gene id: 1750:EL272_RS14620
uniprot id: A0A448N2Q0
names: Similarity
messages: Belongs to the HisA/HisF family.

1750:EL272 RS12680
gene id: 1750:EL272_RS12680
uniprot id: A0A448N1N0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1750:EL272 RS06210
gene id: 1750:EL272_RS06210
uniprot id: A0A3N4D237
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1750:EL272 RS10035
gene id: 1750:EL272_RS10035
uniprot id: A0A448N009
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS10600
gene id: 1750:EL272_RS10600
uniprot id: A0A3N4D444
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1750:EL272 RS01300
gene id: 1750:EL272_RS01300
uniprot id: A0A448MV33
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1750:EL272 RS09430
gene id: 1750:EL272_RS09430
uniprot id: A0A3S4XZ98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1750:EL272 RS03660
gene id: 1750:EL272_RS03660
uniprot id: A0A3S4W5V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1750:EL272 RS06935
gene id: 1750:EL272_RS06935
uniprot id: A0A3N4D3U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS08905
gene id: 1750:EL272_RS08905
uniprot id: A0A3N4D1I2
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1750:EL272 RS15735
gene id: 1750:EL272_RS15735
uniprot id: A0A3S4VJI3
names: Similarity
messages: Belongs to the ferrochelatase family.

1750:EL272 RS04755
gene id: 1750:EL272_RS04755
uniprot id: A0A3N4CXA1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1750:EL272 RS11000
gene id: 1750:EL272_RS11000
uniprot id: A0A3N4D726
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1750:EL272 RS02720
gene id: 1750:EL272_RS02720
uniprot id: A0A4P8ZRG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1750:EL272 RS04535
gene id: 1750:EL272_RS04535
uniprot id: A0A448MX37
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1750:EL272 RS02130
gene id: 1750:EL272_RS02130
uniprot id: A0A448MVL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1750:EL272 RS01195
gene id: 1750:EL272_RS01195
uniprot id: A0A3S5ESH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS14760
gene id: 1750:EL272_RS14760
uniprot id: A0A448N2W2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1750:EL272 RS00020
gene id: 1750:EL272_RS00020
uniprot id: A0A3S5ESG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1750:EL272 RS06215
gene id: 1750:EL272_RS06215
uniprot id: A0A3N4CYP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1750:EL272 RS13465
gene id: 1750:EL272_RS13465
uniprot id: A0A3S4Y0D6
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS12355
gene id: 1750:EL272_RS12355
uniprot id: A0A3S4UGL5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1750:EL272 RS01705
gene id: 1750:EL272_RS01705
uniprot id: A0A3N4CYS8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1750:EL272 RS02505
gene id: 1750:EL272_RS02505
uniprot id: A0A3N4CWJ0
names: Similarity
messages: Belongs to the YoeB family.

1750:EL272 RS09580
gene id: 1750:EL272_RS09580
uniprot id: A0A448MZZ3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1750:EL272 RS03565
gene id: 1750:EL272_RS03565
uniprot id: A0A3N4D5J6
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS06850
gene id: 1750:EL272_RS06850
uniprot id: A0A3N4CUG0
names: Similarity
messages: Belongs to the citrate synthase family.

1750:EL272 RS10310
gene id: 1750:EL272_RS10310
uniprot id: A0A3N4D4B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1750:EL272 RS06930
gene id: 1750:EL272_RS06930
uniprot id: A0A3N4CWN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS05950
gene id: 1750:EL272_RS05950
uniprot id: A0A3S4TZS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1750:EL272 RS12205
gene id: 1750:EL272_RS12205
uniprot id: A0A3S4UW03
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1750:EL272 RS06220
gene id: 1750:EL272_RS06220
uniprot id: A0A3N4CUR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1750:EL272 RS05370
gene id: 1750:EL272_RS05370
uniprot id: A0A448MXC1
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1750:EL272 RS01250
gene id: 1750:EL272_RS01250
uniprot id: A0A448MV24
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09875
gene id: 1750:EL272_RS09875
uniprot id: A0A3N4D4J1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1750:EL272 RS11265
gene id: 1750:EL272_RS11265
uniprot id: A0A3S4XZS2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1750:EL272 RS08340
gene id: 1750:EL272_RS08340
uniprot id: A0A3S4U0N2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1750:EL272 RS02435
gene id: 1750:EL272_RS02435
uniprot id: A0A3S4U420
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1750:EL272 RS13990
gene id: 1750:EL272_RS13990
uniprot id: A0A3S4UWJ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1750:EL272 RS10285
gene id: 1750:EL272_RS10285
uniprot id: A0A448N063
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1750:EL272 RS09400
gene id: 1750:EL272_RS09400
uniprot id: A0A3N4D2C3
names: Similarity
messages: Belongs to the TPP enzyme family.

1750:EL272 RS06240
gene id: 1750:EL272_RS06240
uniprot id: A0A3N4D1W8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1750:EL272 RS05150
gene id: 1750:EL272_RS05150
uniprot id: A0A448MX75
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1750:EL272 RS13870
gene id: 1750:EL272_RS13870
uniprot id: A0A3S4UEJ4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1750:EL272 RS03610
gene id: 1750:EL272_RS03610
uniprot id: A0A3N4CVV8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

1750:EL272 RS00115
gene id: 1750:EL272_RS00115
uniprot id: A0A3S4USJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS04640
gene id: 1750:EL272_RS04640
uniprot id: A0A3S4W654
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS05250
gene id: 1750:EL272_RS05250
uniprot id: A0A448MXA0
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1750:EL272 RS11330
gene id: 1750:EL272_RS11330
uniprot id: A0A3N4D2B0
names: Similarity
messages: Belongs to the UPF0234 family.

1750:EL272 RS09370
gene id: 1750:EL272_RS09370
uniprot id: A0A3N4D196
names: Similarity
messages: Belongs to the cytochrome c-552 family.

1750:EL272 RS02180
gene id: 1750:EL272_RS02180
uniprot id: A0A3N4CWP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1750:EL272 RS01295
gene id: 1750:EL272_RS01295
uniprot id: A0A3N4CXS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1750:EL272 RS00275
gene id: 1750:EL272_RS00275
uniprot id: A0A448MUJ3
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS10225
gene id: 1750:EL272_RS10225
uniprot id: A0A448N055
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1750:EL272 RS14740
gene id: 1750:EL272_RS14740
uniprot id: A0A3S4UET4
names: Similarity
messages: Belongs to the peptidase C40 family.

1750:EL272 RS05765
gene id: 1750:EL272_RS05765
uniprot id: A0A3S4ZS88
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS08010
gene id: 1750:EL272_RS08010
uniprot id: A0A448MZ18
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1750:EL272 RS10155
gene id: 1750:EL272_RS10155
uniprot id: A0A448N024
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS10205
gene id: 1750:EL272_RS10205
uniprot id: A0A3N4D0Q3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1750:EL272 RS00460
gene id: 1750:EL272_RS00460
uniprot id: A0A3N4D510
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1750:EL272 RS07865
gene id: 1750:EL272_RS07865
uniprot id: A0A448MYS4
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1750:EL272 RS06140
gene id: 1750:EL272_RS06140
uniprot id: A0A3N4D899
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1750:EL272 RS08240
gene id: 1750:EL272_RS08240
uniprot id: A0A3S4W7B8
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS05010
gene id: 1750:EL272_RS05010
uniprot id: A0A3N4CVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1750:EL272 RS09780
gene id: 1750:EL272_RS09780
uniprot id: A0A448MZW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1750:EL272 RS04955
gene id: 1750:EL272_RS04955
uniprot id: A0A3N4DK31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1750:EL272 RS14970
gene id: 1750:EL272_RS14970
uniprot id: A0A3N4CY86
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1750:EL272 RS11065
gene id: 1750:EL272_RS11065
uniprot id: A0A3N4D713
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1750:EL272 RS15160
gene id: 1750:EL272_RS15160
uniprot id: A0A448VZN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1750:EL272 RS05260
gene id: 1750:EL272_RS05260
uniprot id: A0A3N4CVT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1750:EL272 RS08390
gene id: 1750:EL272_RS08390
uniprot id: A0A3S4VJF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS09390
gene id: 1750:EL272_RS09390
uniprot id: A0A448MZM5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS04560
gene id: 1750:EL272_RS04560
uniprot id: A0A448MX04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1750:EL272 RS05210
gene id: 1750:EL272_RS05210
uniprot id: A0A3N4CV55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1750:EL272 RS08960
gene id: 1750:EL272_RS08960
uniprot id: A0A448MZI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1750:EL272 RS00030
gene id: 1750:EL272_RS00030
uniprot id: A0A3S4UA67
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS08610
gene id: 1750:EL272_RS08610
uniprot id: A0A448MZG4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1750:EL272 RS15895
gene id: 1750:EL272_RS15895
uniprot id: A0A3N4D190
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1750:EL272 RS02725
gene id: 1750:EL272_RS02725
uniprot id: A0A3N4CYZ6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS04305
gene id: 1750:EL272_RS04305
uniprot id: A0A448MWW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

1750:EL272 RS00200
gene id: 1750:EL272_RS00200
uniprot id: A0A4P8ZZ99
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

1750:EL272 RS09750
gene id: 1750:EL272_RS09750
uniprot id: A0A3N4DDT4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1750:EL272 RS13445
gene id: 1750:EL272_RS13445
uniprot id: A0A3N4D0B1
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS05320
gene id: 1750:EL272_RS05320
uniprot id: A0A3S4TZJ4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1750:EL272 RS06470
gene id: 1750:EL272_RS06470
uniprot id: A0A3N4D8J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1750:EL272 RS01205
gene id: 1750:EL272_RS01205
uniprot id: A0A3S4UAI1
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1750:EL272 RS08230
gene id: 1750:EL272_RS08230
uniprot id: A0A3S4ZT09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1750:EL272 RS07830
gene id: 1750:EL272_RS07830
uniprot id: A0A448MYR4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1750:EL272 RS09380
gene id: 1750:EL272_RS09380
uniprot id: A0A3N4D1B7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS03550
gene id: 1750:EL272_RS03550
uniprot id: A0A3N4DL07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS11270
gene id: 1750:EL272_RS11270
uniprot id: A0A448N0M9
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS02630
gene id: 1750:EL272_RS02630
uniprot id: A0A448MVW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1750:EL272 RS10250
gene id: 1750:EL272_RS10250
uniprot id: A0A3N4D7G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1750:EL272 RS10480
gene id: 1750:EL272_RS10480
uniprot id: A0A3S4UDD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1750:EL272 RS15125
gene id: 1750:EL272_RS15125
uniprot id: A0A448N2S5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1750:EL272 RS04505
gene id: 1750:EL272_RS04505
uniprot id: A0A448MWX4
names: Similarity
messages: Belongs to the PGI/PMI family.

1750:EL272 RS13425
gene id: 1750:EL272_RS13425
uniprot id: A0A3S4UEE2
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS02970
gene id: 1750:EL272_RS02970
uniprot id: A0A3N4D5W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1750:EL272 RS07100
gene id: 1750:EL272_RS07100
uniprot id: A0A3N4CV13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1750:EL272 RS02500
gene id: 1750:EL272_RS02500
uniprot id: A0A3S5ESJ0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1750:EL272 RS11540
gene id: 1750:EL272_RS11540
uniprot id: A0A3N4D031
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1750:EL272 RS07115
gene id: 1750:EL272_RS07115
uniprot id: A0A448MYB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1750:EL272 RS06685
gene id: 1750:EL272_RS06685
uniprot id: A0A3N4CUJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1750:EL272 RS00765
gene id: 1750:EL272_RS00765
uniprot id: A0A3S4TY96
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1750:EL272 RS01305
gene id: 1750:EL272_RS01305
uniprot id: A0A3S4W571
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS03060
gene id: 1750:EL272_RS03060
uniprot id: A0A3S5ESJ6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1750:EL272 RS05835
gene id: 1750:EL272_RS05835
uniprot id: A0A3N4CVK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1750:EL272 RS14575
gene id: 1750:EL272_RS14575
uniprot id: A0A3S4W920
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS02520
gene id: 1750:EL272_RS02520
uniprot id: A0A3S4UAX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1750:EL272 RS08060
gene id: 1750:EL272_RS08060
uniprot id: A0A4P8ZQJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1750:EL272 RS05745
gene id: 1750:EL272_RS05745
uniprot id: A0A448MXM7
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS02835
gene id: 1750:EL272_RS02835
uniprot id: A0A3S4UB05
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1750:EL272 RS13560
gene id: 1750:EL272_RS13560
uniprot id: A0A3S4W8S0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1750:EL272 RS01990
gene id: 1750:EL272_RS01990
uniprot id: A0A448MVL0
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1750:EL272 RS02040
gene id: 1750:EL272_RS02040
uniprot id: A0A3N4D493
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1750:EL272 RS10680
gene id: 1750:EL272_RS10680
uniprot id: A0A3N4D2L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1750:EL272 RS10140
gene id: 1750:EL272_RS10140
uniprot id: A0A3N4D7H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1750:EL272 RS13255
gene id: 1750:EL272_RS13255
uniprot id: A0A3S4Y0B5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1750:EL272 RS08275
gene id: 1750:EL272_RS08275
uniprot id: A0A3N4CVQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1750:EL272 RS09375
gene id: 1750:EL272_RS09375
uniprot id: A0A3N4DQS1
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1750:EL272 RS07645
gene id: 1750:EL272_RS07645
uniprot id: A0A3N4CU36
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1750:EL272 RS09805
gene id: 1750:EL272_RS09805
uniprot id: A0A3N4DDS0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1750:EL272 RS10425
gene id: 1750:EL272_RS10425
uniprot id: A0A3S4XZI9
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1750:EL272 RS10025
gene id: 1750:EL272_RS10025
uniprot id: A0A3N4D7J7
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1750:EL272 RS10435
gene id: 1750:EL272_RS10435
uniprot id: A0A3N4D0L6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1750:EL272 RS12540
gene id: 1750:EL272_RS12540
uniprot id: A0A3N4CZE6
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS04625
gene id: 1750:EL272_RS04625
uniprot id: A0A3S4XXT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1750:EL272 RS06565
gene id: 1750:EL272_RS06565
uniprot id: A0A448MXY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1750:EL272 RS06015
gene id: 1750:EL272_RS06015
uniprot id: A0A3N4CVI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1750:EL272 RS08705
gene id: 1750:EL272_RS08705
uniprot id: A0A448MZD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1750:EL272 RS12195
gene id: 1750:EL272_RS12195
uniprot id: A0A448N180
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1750:EL272 RS07910
gene id: 1750:EL272_RS07910
uniprot id: A0A3N4D383
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1750:EL272 RS12735
gene id: 1750:EL272_RS12735
uniprot id: A0A3S4UGR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1750:EL272 RS05485
gene id: 1750:EL272_RS05485
uniprot id: A0A3N4CVQ4
names: Similarity
messages: Belongs to the peptidase S49 family.

1750:EL272 RS06595
gene id: 1750:EL272_RS06595
uniprot id: A0A3N4CWG1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1750:EL272 RS09715
gene id: 1750:EL272_RS09715
uniprot id: A0A3S4VJT6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1750:EL272 RS08050
gene id: 1750:EL272_RS08050
uniprot id: A0A3S4W7A3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1750:EL272 RS05970
gene id: 1750:EL272_RS05970
uniprot id: A0A4P8ZPM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1750:EL272 RS14735
gene id: 1750:EL272_RS14735
uniprot id: A0A448N2N3
names: Similarity
messages: Belongs to the peptidase C40 family.

1750:EL272 RS05020
gene id: 1750:EL272_RS05020
uniprot id: A0A3N4DK24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1750:EL272 RS10130
gene id: 1750:EL272_RS10130
uniprot id: A0A3S4UFU2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1750:EL272 RS05005
gene id: 1750:EL272_RS05005
uniprot id: A0A3N4CVA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1750:EL272 RS10905
gene id: 1750:EL272_RS10905
uniprot id: A0A3S4UVK6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1750:EL272 RS03515
gene id: 1750:EL272_RS03515
uniprot id: A0A3N4D5K5
names: Similarity
messages: Belongs to the thioredoxin family.

1750:EL272 RS05495
gene id: 1750:EL272_RS05495
uniprot id: A0A448MXH9
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09165
gene id: 1750:EL272_RS09165
uniprot id: A0A3N4DAY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1750:EL272 RS10890
gene id: 1750:EL272_RS10890
uniprot id: A0A3S4W7Z9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1750:EL272 RS05455
gene id: 1750:EL272_RS05455
uniprot id: A0A3N4D4K8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1750:EL272 RS10270
gene id: 1750:EL272_RS10270
uniprot id: A0A3N4D0R2
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1750:EL272 RS04195
gene id: 1750:EL272_RS04195
uniprot id: A0A448MWK6
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS11245
gene id: 1750:EL272_RS11245
uniprot id: A0A3N4D6Y2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS10430
gene id: 1750:EL272_RS10430
uniprot id: A0A3N4D491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1750:EL272 RS11885
gene id: 1750:EL272_RS11885
uniprot id: A0A448N111
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS14095
gene id: 1750:EL272_RS14095
uniprot id: A0A448N2A2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1750:EL272 RS09145
gene id: 1750:EL272_RS09145
uniprot id: A0A3S4U0V8
names: Similarity
messages: Belongs to the YggT family.

1750:EL272 RS09125
gene id: 1750:EL272_RS09125
uniprot id: A0A3S4XZ58
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1750:EL272 RS02125
gene id: 1750:EL272_RS02125
uniprot id: A0A4P8ZXB3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS05800
gene id: 1750:EL272_RS05800
uniprot id: A0A3S4Y6K7
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09350
gene id: 1750:EL272_RS09350
uniprot id: A0A3N4D7W4
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS01505
gene id: 1750:EL272_RS01505
uniprot id: A0A448MV90
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1750:EL272 RS05860
gene id: 1750:EL272_RS05860
uniprot id: A0A3S4W6H7
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS14345
gene id: 1750:EL272_RS14345
uniprot id: A0A448N2F5
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS03185
gene id: 1750:EL272_RS03185
uniprot id: A0A3N4D3P0
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS04070
gene id: 1750:EL272_RS04070
uniprot id: A0A448MWR0
names: Similarity
messages: Belongs to the peptidase S8 family.

1750:EL272 RS02910
gene id: 1750:EL272_RS02910
uniprot id: A0A3S5ESJ4
names: Similarity
messages: Belongs to the FGGY kinase family.

1750:EL272 RS15090
gene id: 1750:EL272_RS15090
uniprot id: A0A448N2V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1750:EL272 RS12780
gene id: 1750:EL272_RS12780
uniprot id: A0A448N1I4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1750:EL272 RS13275
gene id: 1750:EL272_RS13275
uniprot id: A0A3S4W8P6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1750:EL272 RS06305
gene id: 1750:EL272_RS06305
uniprot id: A0A3S4ZFI5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS12020
gene id: 1750:EL272_RS12020
uniprot id: A0A3N4CZR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1750:EL272 RS09735
gene id: 1750:EL272_RS09735
uniprot id: A0A3S4UFQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1750:EL272 RS14185
gene id: 1750:EL272_RS14185
uniprot id: A0A448N2F3
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1750:EL272 RS11220
gene id: 1750:EL272_RS11220
uniprot id: A0A3S4UVP8
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS07980
gene id: 1750:EL272_RS07980
uniprot id: A0A3N4CVU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1750:EL272 RS10815
gene id: 1750:EL272_RS10815
uniprot id: A0A448N0F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1750:EL272 RS09815
gene id: 1750:EL272_RS09815
uniprot id: A0A4P8ZT79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1750:EL272 RS07555
gene id: 1750:EL272_RS07555
uniprot id: A0A3N4D1H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS07925
gene id: 1750:EL272_RS07925
uniprot id: A0A3N4D1C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1750:EL272 RS10325
gene id: 1750:EL272_RS10325
uniprot id: A0A3N4D0Q4
names: Similarity
messages: Belongs to the HSP15 family.

1750:EL272 RS05670
gene id: 1750:EL272_RS05670
uniprot id: A0A3S4TZN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1750:EL272 RS04660
gene id: 1750:EL272_RS04660
uniprot id: A0A448MX31
names: Similarity
messages: Belongs to the IMPACT family.

1750:EL272 RS11450
gene id: 1750:EL272_RS11450
uniprot id: A0A3N4D9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1750:EL272 RS04600
gene id: 1750:EL272_RS04600
uniprot id: A0A3N4D904
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1750:EL272 RS01470
gene id: 1750:EL272_RS01470
uniprot id: A0A448MV52
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

1750:EL272 RS06095
gene id: 1750:EL272_RS06095
uniprot id: A0A3N4CWM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS12875
gene id: 1750:EL272_RS12875
uniprot id: A0A3N4CZE7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1750:EL272 RS03355
gene id: 1750:EL272_RS03355
uniprot id: A0A3S4VHW3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1750:EL272 RS05125
gene id: 1750:EL272_RS05125
uniprot id: A0A3S4XXY2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1750:EL272 RS04960
gene id: 1750:EL272_RS04960
uniprot id: A0A3S4TZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

1750:EL272 RS05505
gene id: 1750:EL272_RS05505
uniprot id: A0A3N4CXH9
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1750:EL272 RS06825
gene id: 1750:EL272_RS06825
uniprot id: A0A3N4D7Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS07880
gene id: 1750:EL272_RS07880
uniprot id: A0A3N4CTZ8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1750:EL272 RS08030
gene id: 1750:EL272_RS08030
uniprot id: A0A3N4D7F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS10380
gene id: 1750:EL272_RS10380
uniprot id: A0A3S4Y838
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS10915
gene id: 1750:EL272_RS10915
uniprot id: A0A3N4D0G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1750:EL272 RS13095
gene id: 1750:EL272_RS13095
uniprot id: A0A448N1S0
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS11875
gene id: 1750:EL272_RS11875
uniprot id: A0A3S4Y8J7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1750:EL272 RS10850
gene id: 1750:EL272_RS10850
uniprot id: A0A3N4D0E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1750:EL272 RS10580
gene id: 1750:EL272_RS10580
uniprot id: A0A3N4DA42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1750:EL272 RS05335
gene id: 1750:EL272_RS05335
uniprot id: A0A448MXG2
names: Similarity
messages: Belongs to the peptidase S9C family.

1750:EL272 RS03230
gene id: 1750:EL272_RS03230
uniprot id: A0A3N4CY13
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1750:EL272 RS15165
gene id: 1750:EL272_RS15165
uniprot id: A0A3S4UWW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1750:EL272 RS01840
gene id: 1750:EL272_RS01840
uniprot id: A0A448MVB4
names: Similarity
messages: Belongs to the GSP E family.

1750:EL272 RS06265
gene id: 1750:EL272_RS06265
uniprot id: A0A3S4Y6S7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1750:EL272 RS13590
gene id: 1750:EL272_RS13590
uniprot id: A0A3N4D164
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1750:EL272 RS03685
gene id: 1750:EL272_RS03685
uniprot id: A0A3N4D5I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1750:EL272 RS03250
gene id: 1750:EL272_RS03250
uniprot id: A0A3S4U4B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1750:EL272 RS08970
gene id: 1750:EL272_RS08970
uniprot id: A0A3N4DQZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1750:EL272 RS04140
gene id: 1750:EL272_RS04140
uniprot id: A0A3N4DKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1750:EL272 RS13200
gene id: 1750:EL272_RS13200
uniprot id: A0A448N1V0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1750:EL272 RS01105
gene id: 1750:EL272_RS01105
uniprot id: A0A3N4DAQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1750:EL272 RS11465
gene id: 1750:EL272_RS11465
uniprot id: A0A448N0S9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1750:EL272 RS05460
gene id: 1750:EL272_RS05460
uniprot id: A0A448MXK4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1750:EL272 RS01770
gene id: 1750:EL272_RS01770
uniprot id: A0A448MVB6
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS02715
gene id: 1750:EL272_RS02715
uniprot id: A0A3S4Y5M8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1750:EL272 RS11035
gene id: 1750:EL272_RS11035
uniprot id: A0A3S4U6W2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1750:EL272 RS11880
gene id: 1750:EL272_RS11880
uniprot id: A0A448N136
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1750:EL272 RS02550
gene id: 1750:EL272_RS02550
uniprot id: A0A3N4CZ21
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1750:EL272 RS10665
gene id: 1750:EL272_RS10665
uniprot id: A0A3N4D0H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1750:EL272 RS01920
gene id: 1750:EL272_RS01920
uniprot id: A0A448MVG6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1750:EL272 RS09865
gene id: 1750:EL272_RS09865
uniprot id: A0A3S4U129
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1750:EL272 RS12105
gene id: 1750:EL272_RS12105
uniprot id: A0A3N4D3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS00130
gene id: 1750:EL272_RS00130
uniprot id: A0A448MUD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS08100
gene id: 1750:EL272_RS08100
uniprot id: A0A448MZ01
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1750:EL272 RS09765
gene id: 1750:EL272_RS09765
uniprot id: A0A3N4D7P3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1750:EL272 RS05085
gene id: 1750:EL272_RS05085
uniprot id: A0A3N4DK14
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1750:EL272 RS06260
gene id: 1750:EL272_RS06260
uniprot id: A0A3N4D456
names: Similarity
messages: Belongs to the UPF0102 family.

1750:EL272 RS09495
gene id: 1750:EL272_RS09495
uniprot id: A0A3S5ESR6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1750:EL272 RS06745
gene id: 1750:EL272_RS06745
uniprot id: A0A3N4CV59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1750:EL272 RS15740
gene id: 1750:EL272_RS15740
uniprot id: A0A3S4UFD9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

1750:EL272 RS00730
gene id: 1750:EL272_RS00730
uniprot id: A0A448MUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS01475
gene id: 1750:EL272_RS01475
uniprot id: A0A3S4USX7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1750:EL272 RS05285
gene id: 1750:EL272_RS05285
uniprot id: A0A3N4D8P0
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS08090
gene id: 1750:EL272_RS08090
uniprot id: A0A3S4Y7F2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1750:EL272 RS11670
gene id: 1750:EL272_RS11670
uniprot id: A0A3S4W885
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS03405
gene id: 1750:EL272_RS03405
uniprot id: A0A3N4D9K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1750:EL272 RS05310
gene id: 1750:EL272_RS05310
uniprot id: A0A3N4CV61
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS10955
gene id: 1750:EL272_RS10955
uniprot id: A0A3S4XZP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1750:EL272 RS10200
gene id: 1750:EL272_RS10200
uniprot id: A0A3N4D4C7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1750:EL272 RS07245
gene id: 1750:EL272_RS07245
uniprot id: A0A448MYH8
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1750:EL272 RS10660
gene id: 1750:EL272_RS10660
uniprot id: A0A3N4D0F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1750:EL272 RS03500
gene id: 1750:EL272_RS03500
uniprot id: A0A448MWC2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1750:EL272 RS07565
gene id: 1750:EL272_RS07565
uniprot id: A0A3N4CU37
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS08305
gene id: 1750:EL272_RS08305
uniprot id: A0A3N4DR96
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1750:EL272 RS04480
gene id: 1750:EL272_RS04480
uniprot id: A0A3S4U4Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS08810
gene id: 1750:EL272_RS08810
uniprot id: A0A3S4U650
names: Similarity
messages: Belongs to the YciI family.

1750:EL272 RS02765
gene id: 1750:EL272_RS02765
uniprot id: A0A448MVU2
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1750:EL272 RS01720
gene id: 1750:EL272_RS01720
uniprot id: A0A3N4CXK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1750:EL272 RS04700
gene id: 1750:EL272_RS04700
uniprot id: A0A448MWZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1750:EL272 RS13885
gene id: 1750:EL272_RS13885
uniprot id: A0A3N4CYX8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

1750:EL272 RS14940
gene id: 1750:EL272_RS14940
uniprot id: A0A3N4D3B3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1750:EL272 RS02220
gene id: 1750:EL272_RS02220
uniprot id: A0A3N4CWU9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1750:EL272 RS03775
gene id: 1750:EL272_RS03775
uniprot id: A0A448MWF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1750:EL272 RS03525
gene id: 1750:EL272_RS03525
uniprot id: A0A3N4CXV9
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1750:EL272 RS08875
gene id: 1750:EL272_RS08875
uniprot id: A0A3S4W7G8
names: Similarity
messages: Belongs to the ribulokinase family.

1750:EL272 RS11310
gene id: 1750:EL272_RS11310
uniprot id: A0A3S4Y8E3
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09570
gene id: 1750:EL272_RS09570
uniprot id: A0A448MZW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1750:EL272 RS11655
gene id: 1750:EL272_RS11655
uniprot id: A0A3N4CZY7
names: Similarity
messages: Belongs to the AHA1 family.

1750:EL272 RS10825
gene id: 1750:EL272_RS10825
uniprot id: A0A3S4UVJ7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1750:EL272 RS09510
gene id: 1750:EL272_RS09510
uniprot id: A0A3N4DAS1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1750:EL272 RS05215
gene id: 1750:EL272_RS05215
uniprot id: A0A3N4CXN4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS07845
gene id: 1750:EL272_RS07845
uniprot id: A0A3S4U0I2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1750:EL272 RS10645
gene id: 1750:EL272_RS10645
uniprot id: A0A3N4D1P1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1750:EL272 RS00910
gene id: 1750:EL272_RS00910
uniprot id: A0A3N4CXH8
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS14555
gene id: 1750:EL272_RS14555
uniprot id: A0A3N4D7U1
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS03655
gene id: 1750:EL272_RS03655
uniprot id: A0A3S4UDH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1750:EL272 RS09155
gene id: 1750:EL272_RS09155
uniprot id: A0A3N4D1F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1750:EL272 RS06110
gene id: 1750:EL272_RS06110
uniprot id: A0A3S4TZU5
names: Similarity
messages: Belongs to the arsA ATPase family.

1750:EL272 RS06150
gene id: 1750:EL272_RS06150
uniprot id: A0A448MXS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1750:EL272 RS11120
gene id: 1750:EL272_RS11120
uniprot id: A0A3N4D9U9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS01610
gene id: 1750:EL272_RS01610
uniprot id: A0A3N4D6S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1750:EL272 RS14525
gene id: 1750:EL272_RS14525
uniprot id: A0A3S4Y9D6
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1750:EL272 RS05270
gene id: 1750:EL272_RS05270
uniprot id: A0A448MXA1
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS01925
gene id: 1750:EL272_RS01925
uniprot id: A0A3S4UT20
names: Similarity
messages: Belongs to the CobH/CbiC family.

1750:EL272 RS04425
gene id: 1750:EL272_RS04425
uniprot id: A0A448MWX6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1750:EL272 RS09190
gene id: 1750:EL272_RS09190
uniprot id: A0A3N4D1C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1750:EL272 RS05295
gene id: 1750:EL272_RS05295
uniprot id: A0A3S4UE23
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1750:EL272 RS12850
gene id: 1750:EL272_RS12850
uniprot id: A0A3S4VKQ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1750:EL272 RS04285
gene id: 1750:EL272_RS04285
uniprot id: A0A3N4CZL6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1750:EL272 RS12870
gene id: 1750:EL272_RS12870
uniprot id: A0A448N1L1
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1750:EL272 RS11570
gene id: 1750:EL272_RS11570
uniprot id: A0A448N0U5
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09290
gene id: 1750:EL272_RS09290
uniprot id: A0A3S4UFK2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1750:EL272 RS07320
gene id: 1750:EL272_RS07320
uniprot id: A0A3S4UEU6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1750:EL272 RS10635
gene id: 1750:EL272_RS10635
uniprot id: A0A448N0B9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1750:EL272 RS02740
gene id: 1750:EL272_RS02740
uniprot id: A0A3N4CY89
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS10505
gene id: 1750:EL272_RS10505
uniprot id: A0A3S4VK10
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1750:EL272 RS05365
gene id: 1750:EL272_RS05365
uniprot id: A0A3S4U4Y9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1750:EL272 RS10775
gene id: 1750:EL272_RS10775
uniprot id: A0A3S4YZ94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1750:EL272 RS12885
gene id: 1750:EL272_RS12885
uniprot id: A0A448N1I9
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS13970
gene id: 1750:EL272_RS13970
uniprot id: A0A3S4UH68
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1750:EL272 RS02420
gene id: 1750:EL272_RS02420
uniprot id: A0A3N4D421
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS02585
gene id: 1750:EL272_RS02585
uniprot id: A0A448MVV2
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS11850
gene id: 1750:EL272_RS11850
uniprot id: A0A3S4VKF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1750:EL272 RS08295
gene id: 1750:EL272_RS08295
uniprot id: A0A3N4CTT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1750:EL272 RS07810
gene id: 1750:EL272_RS07810
uniprot id: A0A3N4D1E1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1750:EL272 RS12100
gene id: 1750:EL272_RS12100
uniprot id: A0A3N4D6L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1750:EL272 RS11605
gene id: 1750:EL272_RS11605
uniprot id: A0A448N133
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09450
gene id: 1750:EL272_RS09450
uniprot id: A0A3S4W7M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1750:EL272 RS07760
gene id: 1750:EL272_RS07760
uniprot id: A0A3S4UF14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1750:EL272 RS10585
gene id: 1750:EL272_RS10585
uniprot id: A0A3N4DDA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1750:EL272 RS04260
gene id: 1750:EL272_RS04260
uniprot id: A0A3N4CY55
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS04990
gene id: 1750:EL272_RS04990
uniprot id: A0A3N4D2M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1750:EL272 RS06860
gene id: 1750:EL272_RS06860
uniprot id: A0A3S5ESN8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1750:EL272 RS01455
gene id: 1750:EL272_RS01455
uniprot id: A0A3N4CYW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1750:EL272 RS06760
gene id: 1750:EL272_RS06760
uniprot id: A0A4P8ZS04
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1750:EL272 RS04055
gene id: 1750:EL272_RS04055
uniprot id: A0A3S4W603
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1750:EL272 RS06630
gene id: 1750:EL272_RS06630
uniprot id: A0A3N4DJ76
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1750:EL272 RS07895
gene id: 1750:EL272_RS07895
uniprot id: A0A3N4CTZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1750:EL272 RS05750
gene id: 1750:EL272_RS05750
uniprot id: A0A448MXK7
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS02350
gene id: 1750:EL272_RS02350
uniprot id: A0A3N4D668
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1750:EL272 RS07965
gene id: 1750:EL272_RS07965
uniprot id: A0A448MYU7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1750:EL272 RS06395
gene id: 1750:EL272_RS06395
uniprot id: A0A3N4D200
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1750:EL272 RS06435
gene id: 1750:EL272_RS06435
uniprot id: A0A448MXZ3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1750:EL272 RS06310
gene id: 1750:EL272_RS06310
uniprot id: A0A3N4CWZ5
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS03210
gene id: 1750:EL272_RS03210
uniprot id: A0A3N4CW49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1750:EL272 RS12630
gene id: 1750:EL272_RS12630
uniprot id: A0A3S4UGQ0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1750:EL272 RS10530
gene id: 1750:EL272_RS10530
uniprot id: A0A3N4DDD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS07730
gene id: 1750:EL272_RS07730
uniprot id: A0A3N4D7K7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1750:EL272 RS02165
gene id: 1750:EL272_RS02165
uniprot id: A0A448MVM0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1750:EL272 RS02775
gene id: 1750:EL272_RS02775
uniprot id: A0A3N4CYY7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1750:EL272 RS10040
gene id: 1750:EL272_RS10040
uniprot id: A0A448N047
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS01915
gene id: 1750:EL272_RS01915
uniprot id: A0A448MVE9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1750:EL272 RS03965
gene id: 1750:EL272_RS03965
uniprot id: A0A3N4CWE5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1750:EL272 RS03700
gene id: 1750:EL272_RS03700
uniprot id: A0A448MWG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS02575
gene id: 1750:EL272_RS02575
uniprot id: A0A3S4TYP6
names: Similarity
messages: Belongs to the UPF0098 family.

1750:EL272 RS11430
gene id: 1750:EL272_RS11430
uniprot id: A0A4P8ZZU9
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS05515
gene id: 1750:EL272_RS05515
uniprot id: A0A448MXC6
names: Similarity
messages: Belongs to the serpin family.

1750:EL272 RS10415
gene id: 1750:EL272_RS10415
uniprot id: A0A3N4DDF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1750:EL272 RS09065
gene id: 1750:EL272_RS09065
uniprot id: A0A3N4D4W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1750:EL272 RS11475
gene id: 1750:EL272_RS11475
uniprot id: A0A3S4XZT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1750:EL272 RS10675
gene id: 1750:EL272_RS10675
uniprot id: A0A3N4D0K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1750:EL272 RS04025
gene id: 1750:EL272_RS04025
uniprot id: A0A3S4XXM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1750:EL272 RS03065
gene id: 1750:EL272_RS03065
uniprot id: A0A3S4UB35
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1750:EL272 RS01445
gene id: 1750:EL272_RS01445
uniprot id: A0A3S4W591
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1750:EL272 RS12330
gene id: 1750:EL272_RS12330
uniprot id: A0A448N1F2
names: Similarity
messages: Belongs to the peptidase S66 family.

1750:EL272 RS11020
gene id: 1750:EL272_RS11020
uniprot id: A0A448N0K5
names: Caution
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1750:EL272 RS07860
gene id: 1750:EL272_RS07860
uniprot id: A0A448MYY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1750:EL272 RS10950
gene id: 1750:EL272_RS10950
uniprot id: A0A448N0J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1750:EL272 RS10875
gene id: 1750:EL272_RS10875
uniprot id: A0A3S4XZN3
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS15155
gene id: 1750:EL272_RS15155
uniprot id: A0A3S4U2V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1750:EL272 RS06130
gene id: 1750:EL272_RS06130
uniprot id: A0A3N4CX42
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1750:EL272 RS03415
gene id: 1750:EL272_RS03415
uniprot id: A0A3N4D3J6
names: Similarity
messages: Belongs to the CutC family.

1750:EL272 RS08780
gene id: 1750:EL272_RS08780
uniprot id: A0A4V1GCT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1750:EL272 RS11965
gene id: 1750:EL272_RS11965
uniprot id: A0A3S4UVX3
names: Similarity
messages: Belongs to the group II decarboxylase family.

1750:EL272 RS05535
gene id: 1750:EL272_RS05535
uniprot id: A0A3N4CZ00
names: Similarity
messages: Belongs to the LOG family.

1750:EL272 RS09320
gene id: 1750:EL272_RS09320
uniprot id: A0A3N4D1C9
names: Similarity
messages: Belongs to the universal stress protein A family.

1750:EL272 RS05940
gene id: 1750:EL272_RS05940
uniprot id: A0A3S4UEB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1750:EL272 RS13400
gene id: 1750:EL272_RS13400
uniprot id: A0A3N4D629
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS06205
gene id: 1750:EL272_RS06205
uniprot id: A0A3N4CWL2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1750:EL272 RS07190
gene id: 1750:EL272_RS07190
uniprot id: A0A3N4D7S9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1750:EL272 RS13490
gene id: 1750:EL272_RS13490
uniprot id: A0A3N4DBV3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS10525
gene id: 1750:EL272_RS10525
uniprot id: A0A3S4UFY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS03555
gene id: 1750:EL272_RS03555
uniprot id: A0A3N4CVX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS11235
gene id: 1750:EL272_RS11235
uniprot id: A0A448VX77
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1750:EL272 RS08935
gene id: 1750:EL272_RS08935
uniprot id: A0A3N4D2J8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1750:EL272 RS10045
gene id: 1750:EL272_RS10045
uniprot id: A0A3S4UFT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1750:EL272 RS04950
gene id: 1750:EL272_RS04950
uniprot id: A0A3N4D225
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1750:EL272 RS04005
gene id: 1750:EL272_RS04005
uniprot id: A0A3N4D3A2
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS00225
gene id: 1750:EL272_RS00225
uniprot id: A0A3S4UCH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS06450
gene id: 1750:EL272_RS06450
uniprot id: A0A448MXZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1750:EL272 RS10235
gene id: 1750:EL272_RS10235
uniprot id: A0A3N4DAD4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1750:EL272 RS03480
gene id: 1750:EL272_RS03480
uniprot id: A0A3S4W5T1
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1750:EL272 RS15055
gene id: 1750:EL272_RS15055
uniprot id: A0A3S4W972
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1750:EL272 RS11175
gene id: 1750:EL272_RS11175
uniprot id: A0A3N4DD16
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1750:EL272 RS12380
gene id: 1750:EL272_RS12380
uniprot id: A0A3S4UW24
names: Similarity
messages: Belongs to the UDPGP type 1 family.

1750:EL272 RS08770
gene id: 1750:EL272_RS08770
uniprot id: A0A3N4D1K8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1750:EL272 RS03635
gene id: 1750:EL272_RS03635
uniprot id: A0A3S4U4F3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS12070
gene id: 1750:EL272_RS12070
uniprot id: A0A3N4CZT4
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1750:EL272 RS09705
gene id: 1750:EL272_RS09705
uniprot id: A0A3N4D7Q3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1750:EL272 RS06070
gene id: 1750:EL272_RS06070
uniprot id: A0A448MXR6
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1750:EL272 RS15040
gene id: 1750:EL272_RS15040
uniprot id: A0A3S4VLB9
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1750:EL272 RS05160
gene id: 1750:EL272_RS05160
uniprot id: A0A3N4D4Q7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1750:EL272 RS01930
gene id: 1750:EL272_RS01930
uniprot id: A0A3S4Y5F1
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1750:EL272 RS11225
gene id: 1750:EL272_RS11225
uniprot id: A0A3N4D2C6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1750:EL272 RS02540
gene id: 1750:EL272_RS02540
uniprot id: A0A448MVU5
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS03280
gene id: 1750:EL272_RS03280
uniprot id: A0A448MW92
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS07550
gene id: 1750:EL272_RS07550
uniprot id: A0A3N4CVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS00005
gene id: 1750:EL272_RS00005
uniprot id: A0A4P8ZUE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1750:EL272 RS09965
gene id: 1750:EL272_RS09965
uniprot id: A0A3N4DDN9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1750:EL272 RS06690
gene id: 1750:EL272_RS06690
uniprot id: A0A4P8ZU65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1750:EL272 RS04695
gene id: 1750:EL272_RS04695
uniprot id: A0A3N4D8Z6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1750:EL272 RS05350
gene id: 1750:EL272_RS05350
uniprot id: A0A448MXC8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1750:EL272 RS02800
gene id: 1750:EL272_RS02800
uniprot id: A0A3N4D0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1750:EL272 RS02440
gene id: 1750:EL272_RS02440
uniprot id: A0A3S4XX68
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1750:EL272 RS07905
gene id: 1750:EL272_RS07905
uniprot id: A0A3N4CW89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1750:EL272 RS03760
gene id: 1750:EL272_RS03760
uniprot id: A0A3N4D9E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1750:EL272 RS00255
gene id: 1750:EL272_RS00255
uniprot id: A0A3S4TY45
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS06295
gene id: 1750:EL272_RS06295
uniprot id: A0A3S4UC52
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1750:EL272 RS03420
gene id: 1750:EL272_RS03420
uniprot id: A0A3N4D035
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1750:EL272 RS10820
gene id: 1750:EL272_RS10820
uniprot id: A0A3N4D1K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1750:EL272 RS12225
gene id: 1750:EL272_RS12225
uniprot id: A0A448N1C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

1750:EL272 RS14175
gene id: 1750:EL272_RS14175
uniprot id: A0A3S4Y0L0
names: Similarity
messages: Belongs to the EutP/PduV family.

1750:EL272 RS06990
gene id: 1750:EL272_RS06990
uniprot id: A0A3N4CUD1
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS11525
gene id: 1750:EL272_RS11525
uniprot id: A0A3N4D6S9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1750:EL272 RS14720
gene id: 1750:EL272_RS14720
uniprot id: A0A448N2S1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1750:EL272 RS14585
gene id: 1750:EL272_RS14585
uniprot id: A0A3N4CYL4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1750:EL272 RS00175
gene id: 1750:EL272_RS00175
uniprot id: A0A3N4D559
names: Similarity
messages: Belongs to the fructosamine kinase family.

1750:EL272 RS13715
gene id: 1750:EL272_RS13715
uniprot id: A0A448N256
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1750:EL272 RS11010
gene id: 1750:EL272_RS11010
uniprot id: A0A4P8ZWI2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1750:EL272 RS10080
gene id: 1750:EL272_RS10080
uniprot id: A0A448N001
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1750:EL272 RS08930
gene id: 1750:EL272_RS08930
uniprot id: A0A3S4VJK9
names: Similarity
messages: Belongs to the peptidase M1 family.

1750:EL272 RS01630
gene id: 1750:EL272_RS01630
uniprot id: A0A3S4USZ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1750:EL272 RS07135
gene id: 1750:EL272_RS07135
uniprot id: A0A3N4D7U0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1750:EL272 RS00530
gene id: 1750:EL272_RS00530
uniprot id: A0A3S4VH19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1750:EL272 RS11755
gene id: 1750:EL272_RS11755
uniprot id: A0A448N101
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS11435
gene id: 1750:EL272_RS11435
uniprot id: A0A3N4DPP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1750:EL272 RS05430
gene id: 1750:EL272_RS05430
uniprot id: A0A448MXH1
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS12490
gene id: 1750:EL272_RS12490
uniprot id: A0A3S4UW34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1750:EL272 RS03445
gene id: 1750:EL272_RS03445
uniprot id: A0A3N4D8R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1750:EL272 RS03350
gene id: 1750:EL272_RS03350
uniprot id: A0A448MW91
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS09180
gene id: 1750:EL272_RS09180
uniprot id: A0A3N4D7Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1750:EL272 RS07970
gene id: 1750:EL272_RS07970
uniprot id: A0A3N4D373
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1750:EL272 RS02010
gene id: 1750:EL272_RS02010
uniprot id: A0A4P8ZMT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1750:EL272 RS10575
gene id: 1750:EL272_RS10575
uniprot id: A0A3N4D2N9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1750:EL272 RS09310
gene id: 1750:EL272_RS09310
uniprot id: A0A4P8ZR79
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1750:EL272 RS09645
gene id: 1750:EL272_RS09645
uniprot id: A0A3N4D4M9
names: Similarity
messages: Belongs to the TlyA family.

1750:EL272 RS06725
gene id: 1750:EL272_RS06725
uniprot id: A0A3N4CWE3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1750:EL272 RS00565
gene id: 1750:EL272_RS00565
uniprot id: A0A3S4UAB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS13040
gene id: 1750:EL272_RS13040
uniprot id: A0A3S4UW95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1750:EL272 RS05915
gene id: 1750:EL272_RS05915
uniprot id: A0A448MXU4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1750:EL272 RS12250
gene id: 1750:EL272_RS12250
uniprot id: A0A3N4CZL8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1750:EL272 RS01255
gene id: 1750:EL272_RS01255
uniprot id: A0A3S5FA68
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS07490
gene id: 1750:EL272_RS07490
uniprot id: A0A448VUW5
names: Similarity
messages: Belongs to the CsoR family.

1750:EL272 RS15925
gene id: 1750:EL272_RS15925
uniprot id: A0A3S4UWL9
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1750:EL272 RS10670
gene id: 1750:EL272_RS10670
uniprot id: A0A3N4DQ25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1750:EL272 RS11250
gene id: 1750:EL272_RS11250
uniprot id: A0A3S4UDN2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1750:EL272 RS04295
gene id: 1750:EL272_RS04295
uniprot id: A0A3S4XXQ3
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS11025
gene id: 1750:EL272_RS11025
uniprot id: A0A3S4UDJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1750:EL272 RS14000
gene id: 1750:EL272_RS14000
uniprot id: A0A3N4D2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS10100
gene id: 1750:EL272_RS10100
uniprot id: A0A3S4U6K6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1750:EL272 RS07045
gene id: 1750:EL272_RS07045
uniprot id: A0A3N4DJ10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1750:EL272 RS05590
gene id: 1750:EL272_RS05590
uniprot id: A0A448MXH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1750:EL272 RS10075
gene id: 1750:EL272_RS10075
uniprot id: A0A3N4D216
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1750:EL272 RS02650
gene id: 1750:EL272_RS02650
uniprot id: A0A448MVT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1750:EL272 RS07035
gene id: 1750:EL272_RS07035
uniprot id: A0A3S4U074
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1750:EL272 RS10590
gene id: 1750:EL272_RS10590
uniprot id: A0A3N4D1Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1750:EL272 RS13645
gene id: 1750:EL272_RS13645
uniprot id: A0A3S4W8S9
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS02610
gene id: 1750:EL272_RS02610
uniprot id: A0A3N4CZ15
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS10445
gene id: 1750:EL272_RS10445
uniprot id: A0A4P8ZX19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1750:EL272 RS10190
gene id: 1750:EL272_RS10190
uniprot id: A0A3N4D1Z4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1750:EL272 RS05850
gene id: 1750:EL272_RS05850
uniprot id: A0A3N4DBM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1750:EL272 RS03510
gene id: 1750:EL272_RS03510
uniprot id: A0A3S4UTH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1750:EL272 RS12605
gene id: 1750:EL272_RS12605
uniprot id: A0A448N1G7
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS15060
gene id: 1750:EL272_RS15060
uniprot id: A0A3N4DN07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1750:EL272 RS03960
gene id: 1750:EL272_RS03960
uniprot id: A0A448MWK3
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS11905
gene id: 1750:EL272_RS11905
uniprot id: A0A448N132
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1750:EL272 RS07740
gene id: 1750:EL272_RS07740
uniprot id: A0A3N4D1F1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1750:EL272 RS02265
gene id: 1750:EL272_RS02265
uniprot id: A0A4P8ZPV2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1750:EL272 RS09075
gene id: 1750:EL272_RS09075
uniprot id: A0A448MZF7
names: Similarity
messages: Belongs to the GcvT family.

1750:EL272 RS14625
gene id: 1750:EL272_RS14625
uniprot id: A0A448N2P7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1750:EL272 RS07890
gene id: 1750:EL272_RS07890
uniprot id: A0A3N4DIN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1750:EL272 RS12200
gene id: 1750:EL272_RS12200
uniprot id: A0A3S4U1T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1750:EL272 RS08180
gene id: 1750:EL272_RS08180
uniprot id: A0A4P8ZQK2
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1750:EL272 RS03235
gene id: 1750:EL272_RS03235
uniprot id: A0A3N4D3N0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS00760
gene id: 1750:EL272_RS00760
uniprot id: A0A3S4W525
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS00085
gene id: 1750:EL272_RS00085
uniprot id: A0A448MUF0
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS05855
gene id: 1750:EL272_RS05855
uniprot id: A0A3S4ZS90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1750:EL272 RS09280
gene id: 1750:EL272_RS09280
uniprot id: A0A3S4VJP7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1750:EL272 RS08035
gene id: 1750:EL272_RS08035
uniprot id: A0A3N4CVT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS13300
gene id: 1750:EL272_RS13300
uniprot id: A0A448N1W9
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS07750
gene id: 1750:EL272_RS07750
uniprot id: A0A4P8ZXK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1750:EL272 RS08105
gene id: 1750:EL272_RS08105
uniprot id: A0A3N4CTW3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1750:EL272 RS07780
gene id: 1750:EL272_RS07780
uniprot id: A0A3S4Y7C3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS03495
gene id: 1750:EL272_RS03495
uniprot id: A0A448MWE7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1750:EL272 RS12445
gene id: 1750:EL272_RS12445
uniprot id: A0A448N1B4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1750:EL272 RS05065
gene id: 1750:EL272_RS05065
uniprot id: A0A3N4D2L2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1750:EL272 RS05730
gene id: 1750:EL272_RS05730
uniprot id: A0A3N4D4F4
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1750:EL272 RS09340
gene id: 1750:EL272_RS09340
uniprot id: A0A3S4UD35
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS06455
gene id: 1750:EL272_RS06455
uniprot id: A0A3N4CYJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1750:EL272 RS11675
gene id: 1750:EL272_RS11675
uniprot id: A0A3N4DPL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1750:EL272 RS10420
gene id: 1750:EL272_RS10420
uniprot id: A0A3N4D1V3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1750:EL272 RS03195
gene id: 1750:EL272_RS03195
uniprot id: A0A448MW86
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09760
gene id: 1750:EL272_RS09760
uniprot id: A0A3N4D273
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1750:EL272 RS13180
gene id: 1750:EL272_RS13180
uniprot id: A0A3N4D0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1750:EL272 RS06655
gene id: 1750:EL272_RS06655
uniprot id: A0A3N4CWF2
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1750:EL272 RS13265
gene id: 1750:EL272_RS13265
uniprot id: A0A448N200
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1750:EL272 RS05740
gene id: 1750:EL272_RS05740
uniprot id: A0A448MXQ1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1750:EL272 RS07330
gene id: 1750:EL272_RS07330
uniprot id: A0A3N4CUX6
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1750:EL272 RS01485
gene id: 1750:EL272_RS01485
uniprot id: A0A448MV62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1750:EL272 RS06290
gene id: 1750:EL272_RS06290
uniprot id: A0A3S5ESN2
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1750:EL272 RS02635
gene id: 1750:EL272_RS02635
uniprot id: A0A3S4U442
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS11550
gene id: 1750:EL272_RS11550
uniprot id: A0A3S4UGC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1750:EL272 RS10930
gene id: 1750:EL272_RS10930
uniprot id: A0A3N4DD50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1750:EL272 RS08915
gene id: 1750:EL272_RS08915
uniprot id: A0A3S4U654
names: Similarity
messages: Belongs to the FPG family.

1750:EL272 RS04555
gene id: 1750:EL272_RS04555
uniprot id: A0A448MWY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1750:EL272 RS03190
gene id: 1750:EL272_RS03190
uniprot id: A0A3N4D083
names: Similarity
messages: Belongs to the AHA1 family.

1750:EL272 RS14265
gene id: 1750:EL272_RS14265
uniprot id: A0A3S4VL53
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1750:EL272 RS07825
gene id: 1750:EL272_RS07825
uniprot id: A0A3S4VJB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1750:EL272 RS00715
gene id: 1750:EL272_RS00715
uniprot id: A0A3S4XWR2
names: Similarity
messages: Belongs to the TPP enzyme family.

1750:EL272 RS01700
gene id: 1750:EL272_RS01700
uniprot id: A0A3S4TYF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1750:EL272 RS08860
gene id: 1750:EL272_RS08860
uniprot id: A0A448MZ85
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

1750:EL272 RS03295
gene id: 1750:EL272_RS03295
uniprot id: A0A448MWA2
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS05190
gene id: 1750:EL272_RS05190
uniprot id: A0A3N4CZ62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1750:EL272 RS10870
gene id: 1750:EL272_RS10870
uniprot id: A0A3S4U6U1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1750:EL272 RS08075
gene id: 1750:EL272_RS08075
uniprot id: A0A3N4D353
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1750:EL272 RS06480
gene id: 1750:EL272_RS06480
uniprot id: A0A3N4CVA5
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1750:EL272 RS01120
gene id: 1750:EL272_RS01120
uniprot id: A0A3N4D1A4
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS07735
gene id: 1750:EL272_RS07735
uniprot id: A0A3S4U5T2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1750:EL272 RS06145
gene id: 1750:EL272_RS06145
uniprot id: A0A3N4CWL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1750:EL272 RS13260
gene id: 1750:EL272_RS13260
uniprot id: A0A3N4CZ80
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09285
gene id: 1750:EL272_RS09285
uniprot id: A0A448MZK4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS06900
gene id: 1750:EL272_RS06900
uniprot id: A0A448MY78
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1750:EL272 RS05975
gene id: 1750:EL272_RS05975
uniprot id: A0A3N4CUV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1750:EL272 RS12855
gene id: 1750:EL272_RS12855
uniprot id: A0A3N4D6A4
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09355
gene id: 1750:EL272_RS09355
uniprot id: A0A3S4U6D6
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS03290
gene id: 1750:EL272_RS03290
uniprot id: A0A3S4TYX2
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS03715
gene id: 1750:EL272_RS03715
uniprot id: A0A3N4CZY4
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS14190
gene id: 1750:EL272_RS14190
uniprot id: A0A3S4VL42
names: Subcellular Location Annotation
messages: Bacterial microcompartment

1750:EL272 RS15470
gene id: 1750:EL272_RS15470
uniprot id: A0A448N023
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1750:EL272 RS03390
gene id: 1750:EL272_RS03390
uniprot id: A0A448MWC1
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1750:EL272 RS07515
gene id: 1750:EL272_RS07515
uniprot id: A0A3N4CU53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1750:EL272 RS14955
gene id: 1750:EL272_RS14955
uniprot id: A0A3S4UHH6
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS12435
gene id: 1750:EL272_RS12435
uniprot id: A0A3N4DP61
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS09885
gene id: 1750:EL272_RS09885
uniprot id: A0A3S4Y7Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

1750:EL272 RS10685
gene id: 1750:EL272_RS10685
uniprot id: A0A3N4DA20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1750:EL272 RS11470
gene id: 1750:EL272_RS11470
uniprot id: A0A3N4D3N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1750:EL272 RS07560
gene id: 1750:EL272_RS07560
uniprot id: A0A3N4CY30
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS06270
gene id: 1750:EL272_RS06270
uniprot id: A0A4P8ZU20
names: Similarity
messages: Belongs to the DprA/Smf family.

1750:EL272 RS14235
gene id: 1750:EL272_RS14235
uniprot id: A0A448N2F6
names: Similarity
messages: Belongs to the PduL family.

1750:EL272 RS15455
gene id: 1750:EL272_RS15455
uniprot id: A0A448MZC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS08235
gene id: 1750:EL272_RS08235
uniprot id: A0A3S4UFA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1750:EL272 RS14715
gene id: 1750:EL272_RS14715
uniprot id: A0A448N2J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1750:EL272 RS02395
gene id: 1750:EL272_RS02395
uniprot id: A0A3S4UT60
names: Similarity
messages: Belongs to the GARS family.

1750:EL272 RS08760
gene id: 1750:EL272_RS08760
uniprot id: A0A3S4UUZ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1750:EL272 RS00045
gene id: 1750:EL272_RS00045
uniprot id: A0A3S4XWK6
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS10900
gene id: 1750:EL272_RS10900
uniprot id: A0A3N4D0B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1750:EL272 RS12880
gene id: 1750:EL272_RS12880
uniprot id: A0A3N4DNX9
names: Subcellular Location Annotation
messages: Membrane

1750:EL272 RS00135
gene id: 1750:EL272_RS00135
uniprot id: A0A3S5ESG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1750:EL272 RS04645
gene id: 1750:EL272_RS04645
uniprot id: A0A3N4CW22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1750:EL272 RS08400
gene id: 1750:EL272_RS08400
uniprot id: A0A3S4UFB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1750:EL272 RS00525
gene id: 1750:EL272_RS00525
uniprot id: A0A3S4XWN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1750:EL272 RS11425
gene id: 1750:EL272_RS11425
uniprot id: A0A448N0R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1750:EL272 RS08195
gene id: 1750:EL272_RS08195
uniprot id: A0A3S5AI54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1750:EL272 RS03820
gene id: 1750:EL272_RS03820
uniprot id: A0A3S4W5X3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS08175
gene id: 1750:EL272_RS08175
uniprot id: A0A3N4CUK0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1750:EL272 RS08190
gene id: 1750:EL272_RS08190
uniprot id: A0A448MYV9
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

1750:EL272 RS08725
gene id: 1750:EL272_RS08725
uniprot id: A0A3N4D1L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1750:EL272 RS06115
gene id: 1750:EL272_RS06115
uniprot id: A0A3S4Y6Q3
names: Similarity
messages: Belongs to the arsA ATPase family.

1750:EL272 RS06490
gene id: 1750:EL272_RS06490
uniprot id: A0A3S4XYF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1750:EL272 RS08070
gene id: 1750:EL272_RS08070
uniprot id: A0A3N4CW53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1750:EL272 RS09640
gene id: 1750:EL272_RS09640
uniprot id: A0A3N4D7R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1750:EL272 RS15130
gene id: 1750:EL272_RS15130
uniprot id: A0A3N4D7J1
names: Similarity
messages: Belongs to the ParB family.

1750:EL272 RS02665
gene id: 1750:EL272_RS02665
uniprot id: A0A3N4CWF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1750:EL272 RS08790
gene id: 1750:EL272_RS08790
uniprot id: A0A3N4D1M4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1750:EL272 RS09745
gene id: 1750:EL272_RS09745
uniprot id: A0A3N4DAN3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1750:EL272 RS08055
gene id: 1750:EL272_RS08055
uniprot id: A0A3N4CUM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1750:EL272 RS09680
gene id: 1750:EL272_RS09680
uniprot id: A0A3N4D173
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.