1748:ASQ49 RS11950
gene id: 1748:ASQ49_RS11950
uniprot id: A0A806VH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS11740
gene id: 1748:ASQ49_RS11740
uniprot id: A0A806VDP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1748:ASQ49 RS15705
gene id: 1748:ASQ49_RS15705
uniprot id: A0A806VI71
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1748:ASQ49 RS00995
gene id: 1748:ASQ49_RS00995
uniprot id: A0A806VKW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS08460
gene id: 1748:ASQ49_RS08460
uniprot id: A0A142KGG2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1748:ASQ49 RS15620
gene id: 1748:ASQ49_RS15620
uniprot id: A0A806VEV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1748:ASQ49 RS15165
gene id: 1748:ASQ49_RS15165
uniprot id: A0A806VI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS12940
gene id: 1748:ASQ49_RS12940
uniprot id: A0A806VC52
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1748:ASQ49 RS14325
gene id: 1748:ASQ49_RS14325
uniprot id: A0A806VDE5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS01205
gene id: 1748:ASQ49_RS01205
uniprot id: A0A806W222
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1748:ASQ49 RS02625
gene id: 1748:ASQ49_RS02625
uniprot id: A0A806V9W4
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1748:ASQ49 RS10075
gene id: 1748:ASQ49_RS10075
uniprot id: A0A806VD05
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1748:ASQ49 RS13515
gene id: 1748:ASQ49_RS13515
uniprot id: A0A806VF91
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS12605
gene id: 1748:ASQ49_RS12605
uniprot id: A0A142KEB5
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1748:ASQ49 RS01555
gene id: 1748:ASQ49_RS01555
uniprot id: A0A806VD53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1748:ASQ49 RS15425
gene id: 1748:ASQ49_RS15425
uniprot id: A0A806VDX1
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS03030
gene id: 1748:ASQ49_RS03030
uniprot id: A0A806VXP1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1748:ASQ49 RS12075
gene id: 1748:ASQ49_RS12075
uniprot id: A0A806VH30
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1748:ASQ49 RS03720
gene id: 1748:ASQ49_RS03720
uniprot id: A0A806VGK2
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS04855
gene id: 1748:ASQ49_RS04855
uniprot id: A0A806VEK8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS03975
gene id: 1748:ASQ49_RS03975
uniprot id: A0A806VGN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS09195
gene id: 1748:ASQ49_RS09195
uniprot id: A0A142KG44
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1748:ASQ49 RS15045
gene id: 1748:ASQ49_RS15045
uniprot id: A0A806VHY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS00605
gene id: 1748:ASQ49_RS00605
uniprot id: A0A806VX14
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS08415
gene id: 1748:ASQ49_RS08415
uniprot id: A0A142KGH0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1748:ASQ49 RS12240
gene id: 1748:ASQ49_RS12240
uniprot id: A0A142KE54
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1748:ASQ49 RS07540
gene id: 1748:ASQ49_RS07540
uniprot id: A0A806W277
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1748:ASQ49 RS03510
gene id: 1748:ASQ49_RS03510
uniprot id: A0A806VA81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS08720
gene id: 1748:ASQ49_RS08720
uniprot id: A0A806VAF5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1748:ASQ49 RS09020
gene id: 1748:ASQ49_RS09020
uniprot id: A0A142KG73
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1748:ASQ49 RS13550
gene id: 1748:ASQ49_RS13550
uniprot id: A0A1P8TVH2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1748:ASQ49 RS15145
gene id: 1748:ASQ49_RS15145
uniprot id: A0A142KKT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1748:ASQ49 RS12475
gene id: 1748:ASQ49_RS12475
uniprot id: A0A806VJL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1748:ASQ49 RS01540
gene id: 1748:ASQ49_RS01540
uniprot id: A0A806VL48
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS08265
gene id: 1748:ASQ49_RS08265
uniprot id: A0A806VA82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1748:ASQ49 RS05360
gene id: 1748:ASQ49_RS05360
uniprot id: A0A806V9A2
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1748:ASQ49 RS04875
gene id: 1748:ASQ49_RS04875
uniprot id: A0A806VAU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS04655
gene id: 1748:ASQ49_RS04655
uniprot id: A0A806VEH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1748:ASQ49 RS13605
gene id: 1748:ASQ49_RS13605
uniprot id: A0A806VCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1748:ASQ49 RS15670
gene id: 1748:ASQ49_RS15670
uniprot id: A0A806VE11
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS05525
gene id: 1748:ASQ49_RS05525
uniprot id: A0A142KHS5
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1748:ASQ49 RS14150
gene id: 1748:ASQ49_RS14150
uniprot id: A0A142KDQ1
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS00275
gene id: 1748:ASQ49_RS00275
uniprot id: A0A142KK68
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1748:ASQ49 RS02110
gene id: 1748:ASQ49_RS02110
uniprot id: A0A806V849
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS02195
gene id: 1748:ASQ49_RS02195
uniprot id: A0A806VFX3
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS03140
gene id: 1748:ASQ49_RS03140
uniprot id: A0A806VXZ0
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS08685
gene id: 1748:ASQ49_RS08685
uniprot id: A0A806VB29
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1748:ASQ49 RS08775
gene id: 1748:ASQ49_RS08775
uniprot id: A0A142KGA7
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS09155
gene id: 1748:ASQ49_RS09155
uniprot id: A0A142KG52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1748:ASQ49 RS02040
gene id: 1748:ASQ49_RS02040
uniprot id: A0A806V9L5
names: Subunit
messages: Homotetramer.

1748:ASQ49 RS01325
gene id: 1748:ASQ49_RS01325
uniprot id: A0A142KJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS05735
gene id: 1748:ASQ49_RS05735
uniprot id: A0A806VB48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS01910
gene id: 1748:ASQ49_RS01910
uniprot id: A0A806V7N7
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS01920
gene id: 1748:ASQ49_RS01920
uniprot id: A0A806V7T1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1748:ASQ49 RS09855
gene id: 1748:ASQ49_RS09855
uniprot id: A0A806VII7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1748:ASQ49 RS05260
gene id: 1748:ASQ49_RS05260
uniprot id: A0A142KHY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1748:ASQ49 RS00430
gene id: 1748:ASQ49_RS00430
uniprot id: A0A806W215
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1748:ASQ49 RS02180
gene id: 1748:ASQ49_RS02180
uniprot id: A0A142KJ35
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1748:ASQ49 RS12720
gene id: 1748:ASQ49_RS12720
uniprot id: A0A142KED6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1748:ASQ49 RS12870
gene id: 1748:ASQ49_RS12870
uniprot id: A0A806W0L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1748:ASQ49 RS11400
gene id: 1748:ASQ49_RS11400
uniprot id: A0A806VBR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1748:ASQ49 RS14545
gene id: 1748:ASQ49_RS14545
uniprot id: A0A142KL43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1748:ASQ49 RS15600
gene id: 1748:ASQ49_RS15600
uniprot id: A0A806VDN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

1748:ASQ49 RS05440
gene id: 1748:ASQ49_RS05440
uniprot id: A0A806VYN2
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

1748:ASQ49 RS00185
gene id: 1748:ASQ49_RS00185
uniprot id: A0A806V741
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS15735
gene id: 1748:ASQ49_RS15735
uniprot id: A0A806VDX5
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1748:ASQ49 RS05450
gene id: 1748:ASQ49_RS05450
uniprot id: A0A806VYD8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1748:ASQ49 RS10145
gene id: 1748:ASQ49_RS10145
uniprot id: A0A806VB94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1748:ASQ49 RS11860
gene id: 1748:ASQ49_RS11860
uniprot id: A0A806VBM9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1748:ASQ49 RS06555
gene id: 1748:ASQ49_RS06555
uniprot id: A0A806VYQ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1748:ASQ49 RS14515
gene id: 1748:ASQ49_RS14515
uniprot id: A0A142KL48
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1748:ASQ49 RS05290
gene id: 1748:ASQ49_RS05290
uniprot id: A0A806V992
names: Similarity
messages: Belongs to the thioredoxin family.

1748:ASQ49 RS06020
gene id: 1748:ASQ49_RS06020
uniprot id: A0A806V9Z2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS02980
gene id: 1748:ASQ49_RS02980
uniprot id: A0A806VGB2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1748:ASQ49 RS00715
gene id: 1748:ASQ49_RS00715
uniprot id: A0A806V7J9
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS12780
gene id: 1748:ASQ49_RS12780
uniprot id: A0A806W0W9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1748:ASQ49 RS16520
gene id: 1748:ASQ49_RS16520
uniprot id: A0A806W1P5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1748:ASQ49 RS10280
gene id: 1748:ASQ49_RS10280
uniprot id: A0A806VD35
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1748:ASQ49 RS09065
gene id: 1748:ASQ49_RS09065
uniprot id: A0A142KG65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1748:ASQ49 RS07945
gene id: 1748:ASQ49_RS07945
uniprot id: A0A806VAF6
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS09720
gene id: 1748:ASQ49_RS09720
uniprot id: A0A806VIH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1748:ASQ49 RS11610
gene id: 1748:ASQ49_RS11610
uniprot id: A0A806VDN0
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1748:ASQ49 RS12530
gene id: 1748:ASQ49_RS12530
uniprot id: A0A806VQY2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1748:ASQ49 RS09665
gene id: 1748:ASQ49_RS09665
uniprot id: A0A142KFW1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1748:ASQ49 RS08235
gene id: 1748:ASQ49_RS08235
uniprot id: A0A142KGK1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1748:ASQ49 RS15210
gene id: 1748:ASQ49_RS15210
uniprot id: A0A806VD70
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1748:ASQ49 RS06405
gene id: 1748:ASQ49_RS06405
uniprot id: A0A142KHD7
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS13950
gene id: 1748:ASQ49_RS13950
uniprot id: A0A806VHK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1748:ASQ49 RS10965
gene id: 1748:ASQ49_RS10965
uniprot id: A0A806VBA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1748:ASQ49 RS14850
gene id: 1748:ASQ49_RS14850
uniprot id: A0A142KKY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1748:ASQ49 RS00790
gene id: 1748:ASQ49_RS00790
uniprot id: A0A806VCR3
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1748:ASQ49 RS13710
gene id: 1748:ASQ49_RS13710
uniprot id: A0A806VEL4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1748:ASQ49 RS10450
gene id: 1748:ASQ49_RS10450
uniprot id: A0A806VIR3
names: Similarity
messages: Belongs to the peptidase M1 family.

1748:ASQ49 RS06075
gene id: 1748:ASQ49_RS06075
uniprot id: A0A142KHI3
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS13150
gene id: 1748:ASQ49_RS13150
uniprot id: A0A806VEC3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1748:ASQ49 RS16280
gene id: 1748:ASQ49_RS16280
uniprot id: A0A142KME7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1748:ASQ49 RS01195
gene id: 1748:ASQ49_RS01195
uniprot id: A0A806VKZ5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS08865
gene id: 1748:ASQ49_RS08865
uniprot id: A0A806VAU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1748:ASQ49 RS13650
gene id: 1748:ASQ49_RS13650
uniprot id: A0A806VD52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1748:ASQ49 RS11725
gene id: 1748:ASQ49_RS11725
uniprot id: A0A806VBL2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1748:ASQ49 RS05600
gene id: 1748:ASQ49_RS05600
uniprot id: A0A806VB34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS06245
gene id: 1748:ASQ49_RS06245
uniprot id: A0A806VYW7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1748:ASQ49 RS07140
gene id: 1748:ASQ49_RS07140
uniprot id: A0A806VFF9
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS13160
gene id: 1748:ASQ49_RS13160
uniprot id: A0A806W113
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1748:ASQ49 RS09790
gene id: 1748:ASQ49_RS09790
uniprot id: A0A806VII1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1748:ASQ49 RS12310
gene id: 1748:ASQ49_RS12310
uniprot id: A0A142KE67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1748:ASQ49 RS05045
gene id: 1748:ASQ49_RS05045
uniprot id: A0A806V952
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1748:ASQ49 RS09755
gene id: 1748:ASQ49_RS09755
uniprot id: A0A806VZZ6
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS08760
gene id: 1748:ASQ49_RS08760
uniprot id: A0A142KGB0
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1748:ASQ49 RS10590
gene id: 1748:ASQ49_RS10590
uniprot id: A0A806VGE6
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS14045
gene id: 1748:ASQ49_RS14045
uniprot id: A0A806W1C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1748:ASQ49 RS14220
gene id: 1748:ASQ49_RS14220
uniprot id: A0A806VRP5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS01680
gene id: 1748:ASQ49_RS01680
uniprot id: A0A806VFW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1748:ASQ49 RS07990
gene id: 1748:ASQ49_RS07990
uniprot id: A0A806VFS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1748:ASQ49 RS06395
gene id: 1748:ASQ49_RS06395
uniprot id: A0A806V9R3
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1748:ASQ49 RS13175
gene id: 1748:ASQ49_RS13175
uniprot id: A0A806VR78
names: Similarity
messages: Belongs to the IMPACT family.

1748:ASQ49 RS00570
gene id: 1748:ASQ49_RS00570
uniprot id: A0A806VKN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS09170
gene id: 1748:ASQ49_RS09170
uniprot id: A0A806VAK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1748:ASQ49 RS12200
gene id: 1748:ASQ49_RS12200
uniprot id: A0A142KE47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1748:ASQ49 RS13440
gene id: 1748:ASQ49_RS13440
uniprot id: A0A806VCC8
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS07110
gene id: 1748:ASQ49_RS07110
uniprot id: A0A806VA36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1748:ASQ49 RS07855
gene id: 1748:ASQ49_RS07855
uniprot id: A0A142KLU7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1748:ASQ49 RS05980
gene id: 1748:ASQ49_RS05980
uniprot id: A0A806V9N8
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

1748:ASQ49 RS12825
gene id: 1748:ASQ49_RS12825
uniprot id: A0A1P8TVV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1748:ASQ49 RS04295
gene id: 1748:ASQ49_RS04295
uniprot id: A0A806V8T6
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS13570
gene id: 1748:ASQ49_RS13570
uniprot id: A0A806VK30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1748:ASQ49 RS09125
gene id: 1748:ASQ49_RS09125
uniprot id: A0A142KG56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1748:ASQ49 RS13720
gene id: 1748:ASQ49_RS13720
uniprot id: A0A806W183
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

1748:ASQ49 RS12215
gene id: 1748:ASQ49_RS12215
uniprot id: A0A806VC89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1748:ASQ49 RS12830
gene id: 1748:ASQ49_RS12830
uniprot id: A0A142KEF5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1748:ASQ49 RS12365
gene id: 1748:ASQ49_RS12365
uniprot id: A0A806VH57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS13820
gene id: 1748:ASQ49_RS13820
uniprot id: A0A806VHI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1748:ASQ49 RS08015
gene id: 1748:ASQ49_RS08015
uniprot id: A0A806VZE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS09560
gene id: 1748:ASQ49_RS09560
uniprot id: A0A806VID8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1748:ASQ49 RS03960
gene id: 1748:ASQ49_RS03960
uniprot id: A0A806VG01
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1748:ASQ49 RS10875
gene id: 1748:ASQ49_RS10875
uniprot id: A0A142KFE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1748:ASQ49 RS10560
gene id: 1748:ASQ49_RS10560
uniprot id: A0A806VBI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1748:ASQ49 RS03070
gene id: 1748:ASQ49_RS03070
uniprot id: A0A806V8N1
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS11115
gene id: 1748:ASQ49_RS11115
uniprot id: A0A142KFA2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1748:ASQ49 RS11235
gene id: 1748:ASQ49_RS11235
uniprot id: A0A142KF82
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1748:ASQ49 RS08320
gene id: 1748:ASQ49_RS08320
uniprot id: A0A142KGI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1748:ASQ49 RS04590
gene id: 1748:ASQ49_RS04590
uniprot id: A0A806V8P1
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1748:ASQ49 RS02290
gene id: 1748:ASQ49_RS02290
uniprot id: A0A806VXF0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1748:ASQ49 RS15335
gene id: 1748:ASQ49_RS15335
uniprot id: A0A806W1D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1748:ASQ49 RS14935
gene id: 1748:ASQ49_RS14935
uniprot id: A0A806VD26
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1748:ASQ49 RS09595
gene id: 1748:ASQ49_RS09595
uniprot id: A0A142KFX3
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS08600
gene id: 1748:ASQ49_RS08600
uniprot id: A0A142KGD7
names: Similarity
messages: Belongs to the AHA1 family.

1748:ASQ49 RS10570
gene id: 1748:ASQ49_RS10570
uniprot id: A0A806VQ41
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1748:ASQ49 RS15940
gene id: 1748:ASQ49_RS15940
uniprot id: A0A806VDT9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1748:ASQ49 RS15185
gene id: 1748:ASQ49_RS15185
uniprot id: A0A806W1R4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1748:ASQ49 RS05860
gene id: 1748:ASQ49_RS05860
uniprot id: A0A806V9H5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

1748:ASQ49 RS16125
gene id: 1748:ASQ49_RS16125
uniprot id: A0A142KKE0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1748:ASQ49 RS13640
gene id: 1748:ASQ49_RS13640
uniprot id: A0A142KF05
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS05775
gene id: 1748:ASQ49_RS05775
uniprot id: A0A806VN20
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS10090
gene id: 1748:ASQ49_RS10090
uniprot id: A0A142KFP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS14010
gene id: 1748:ASQ49_RS14010
uniprot id: A0A806VCL7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1748:ASQ49 RS06440
gene id: 1748:ASQ49_RS06440
uniprot id: A0A806V9H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS01725
gene id: 1748:ASQ49_RS01725
uniprot id: A0A806V7L5
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1748:ASQ49 RS02280
gene id: 1748:ASQ49_RS02280
uniprot id: A0A806VXN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1748:ASQ49 RS11830
gene id: 1748:ASQ49_RS11830
uniprot id: A0A142KDZ0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1748:ASQ49 RS12030
gene id: 1748:ASQ49_RS12030
uniprot id: A0A806W0B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1748:ASQ49 RS06185
gene id: 1748:ASQ49_RS06185
uniprot id: A0A806VYL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS16420
gene id: 1748:ASQ49_RS16420
uniprot id: A0A806VLE6
names: Similarity
messages: Belongs to the AHA1 family.

1748:ASQ49 RS14845
gene id: 1748:ASQ49_RS14845
uniprot id: A0A3Q9CQN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1748:ASQ49 RS15095
gene id: 1748:ASQ49_RS15095
uniprot id: A0A806VKU4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1748:ASQ49 RS05555
gene id: 1748:ASQ49_RS05555
uniprot id: A0A806VYP5
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1748:ASQ49 RS06700
gene id: 1748:ASQ49_RS06700
uniprot id: A0A142KH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS15265
gene id: 1748:ASQ49_RS15265
uniprot id: A0A806W1D4
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS09360
gene id: 1748:ASQ49_RS09360
uniprot id: A0A806VZV6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1748:ASQ49 RS10040
gene id: 1748:ASQ49_RS10040
uniprot id: A0A142KFQ2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1748:ASQ49 RS16955
gene id: 1748:ASQ49_RS16955
uniprot id: A0A1P8TWH4
names: Similarity
messages: Belongs to the DprA/Smf family.

1748:ASQ49 RS12520
gene id: 1748:ASQ49_RS12520
uniprot id: A0A806VCD5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1748:ASQ49 RS01715
gene id: 1748:ASQ49_RS01715
uniprot id: A0A142KJB0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1748:ASQ49 RS04335
gene id: 1748:ASQ49_RS04335
uniprot id: A0A806VGT2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1748:ASQ49 RS04605
gene id: 1748:ASQ49_RS04605
uniprot id: A0A142KI60
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS09700
gene id: 1748:ASQ49_RS09700
uniprot id: A0A806VZY8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1748:ASQ49 RS15325
gene id: 1748:ASQ49_RS15325
uniprot id: A0A806W1S5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1748:ASQ49 RS18285
gene id: 1748:ASQ49_RS18285
uniprot id: A0A806VCB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1748:ASQ49 RS02345
gene id: 1748:ASQ49_RS02345
uniprot id: A0A806VSW7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1748:ASQ49 RS00410
gene id: 1748:ASQ49_RS00410
uniprot id: A0A806V771
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1748:ASQ49 RS04460
gene id: 1748:ASQ49_RS04460
uniprot id: A0A806VEF5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS00740
gene id: 1748:ASQ49_RS00740
uniprot id: A0A806VCQ4
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1748:ASQ49 RS12675
gene id: 1748:ASQ49_RS12675
uniprot id: A0A806VCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1748:ASQ49 RS12260
gene id: 1748:ASQ49_RS12260
uniprot id: A0A806W0Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1748:ASQ49 RS02185
gene id: 1748:ASQ49_RS02185
uniprot id: A0A806V7S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1748:ASQ49 RS14820
gene id: 1748:ASQ49_RS14820
uniprot id: A0A142KKZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1748:ASQ49 RS02160
gene id: 1748:ASQ49_RS02160
uniprot id: A0A806VXM5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS12385
gene id: 1748:ASQ49_RS12385
uniprot id: A0A806VC43
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1748:ASQ49 RS07275
gene id: 1748:ASQ49_RS07275
uniprot id: A0A142KGZ8
names: Similarity
messages: Belongs to the Dps family.

1748:ASQ49 RS16245
gene id: 1748:ASQ49_RS16245
uniprot id: A0A142KKC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1748:ASQ49 RS08840
gene id: 1748:ASQ49_RS08840
uniprot id: A0A142KG98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1748:ASQ49 RS09630
gene id: 1748:ASQ49_RS09630
uniprot id: A0A806VGB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS02320
gene id: 1748:ASQ49_RS02320
uniprot id: A0A142KIZ1
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1748:ASQ49 RS05105
gene id: 1748:ASQ49_RS05105
uniprot id: A0A1P8TZC0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1748:ASQ49 RS12755
gene id: 1748:ASQ49_RS12755
uniprot id: A0A806VC24
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1748:ASQ49 RS10125
gene id: 1748:ASQ49_RS10125
uniprot id: A0A806VGH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1748:ASQ49 RS09180
gene id: 1748:ASQ49_RS09180
uniprot id: A0A142KG47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1748:ASQ49 RS06125
gene id: 1748:ASQ49_RS06125
uniprot id: A0A806VN68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS13255
gene id: 1748:ASQ49_RS13255
uniprot id: A0A806VCI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1748:ASQ49 RS09775
gene id: 1748:ASQ49_RS09775
uniprot id: A0A806W291
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS08400
gene id: 1748:ASQ49_RS08400
uniprot id: A0A806VEW7
names: Similarity
messages: Belongs to the GARS family.

1748:ASQ49 RS07010
gene id: 1748:ASQ49_RS07010
uniprot id: A0A806V9P9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1748:ASQ49 RS06780
gene id: 1748:ASQ49_RS06780
uniprot id: A0A806VEU9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1748:ASQ49 RS10495
gene id: 1748:ASQ49_RS10495
uniprot id: A0A806VBH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
messages: In the N-terminal section; belongs to the LPG synthetase family.
messages: Membrane

1748:ASQ49 RS10595
gene id: 1748:ASQ49_RS10595
uniprot id: A0A806VB51
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS00485
gene id: 1748:ASQ49_RS00485
uniprot id: A0A806VX00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1748:ASQ49 RS08525
gene id: 1748:ASQ49_RS08525
uniprot id: A0A806VP80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS12415
gene id: 1748:ASQ49_RS12415
uniprot id: A0A806VQW4
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1748:ASQ49 RS14655
gene id: 1748:ASQ49_RS14655
uniprot id: A0A806VD75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1748:ASQ49 RS02275
gene id: 1748:ASQ49_RS02275
uniprot id: A0A142KJ00
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1748:ASQ49 RS11475
gene id: 1748:ASQ49_RS11475
uniprot id: A0A142KDT8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1748:ASQ49 RS14585
gene id: 1748:ASQ49_RS14585
uniprot id: A0A806VKJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1748:ASQ49 RS07615
gene id: 1748:ASQ49_RS07615
uniprot id: A0A142KGU3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1748:ASQ49 RS03265
gene id: 1748:ASQ49_RS03265
uniprot id: A0A806V8R1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1748:ASQ49 RS09110
gene id: 1748:ASQ49_RS09110
uniprot id: A0A142KG59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1748:ASQ49 RS14990
gene id: 1748:ASQ49_RS14990
uniprot id: A0A806VHY3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1748:ASQ49 RS12630
gene id: 1748:ASQ49_RS12630
uniprot id: A0A806VCF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1748:ASQ49 RS09610
gene id: 1748:ASQ49_RS09610
uniprot id: A0A142KFX0
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS13880
gene id: 1748:ASQ49_RS13880
uniprot id: A0A806VK77
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1748:ASQ49 RS11025
gene id: 1748:ASQ49_RS11025
uniprot id: A0A806VGT3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1748:ASQ49 RS03610
gene id: 1748:ASQ49_RS03610
uniprot id: A0A806V8I5
names: Similarity
messages: Belongs to the peptidase C69 family.

1748:ASQ49 RS01925
gene id: 1748:ASQ49_RS01925
uniprot id: A0A806V9J9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1748:ASQ49 RS05885
gene id: 1748:ASQ49_RS05885
uniprot id: A0A806VYI0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1748:ASQ49 RS03675
gene id: 1748:ASQ49_RS03675
uniprot id: A0A806V8X7
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1748:ASQ49 RS16225
gene id: 1748:ASQ49_RS16225
uniprot id: A0A806VDL0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1748:ASQ49 RS11090
gene id: 1748:ASQ49_RS11090
uniprot id: A0A806VBL5
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1748:ASQ49 RS08780
gene id: 1748:ASQ49_RS08780
uniprot id: A0A142KGA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1748:ASQ49 RS09140
gene id: 1748:ASQ49_RS09140
uniprot id: A0A142KG54
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1748:ASQ49 RS06470
gene id: 1748:ASQ49_RS06470
uniprot id: A0A806V9V9
names: Similarity
messages: Belongs to the AHA1 family.

1748:ASQ49 RS09835
gene id: 1748:ASQ49_RS09835
uniprot id: A0A142KFT4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1748:ASQ49 RS11640
gene id: 1748:ASQ49_RS11640
uniprot id: A0A806W077
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1748:ASQ49 RS11875
gene id: 1748:ASQ49_RS11875
uniprot id: A0A806VH13
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1748:ASQ49 RS02085
gene id: 1748:ASQ49_RS02085
uniprot id: A0A806VDE2
names: Similarity
messages: Belongs to the carbamate kinase family.

1748:ASQ49 RS02880
gene id: 1748:ASQ49_RS02880
uniprot id: A0A806VA04
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS01450
gene id: 1748:ASQ49_RS01450
uniprot id: A0A142KJF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS13085
gene id: 1748:ASQ49_RS13085
uniprot id: A0A142KEK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1748:ASQ49 RS12195
gene id: 1748:ASQ49_RS12195
uniprot id: A0A806VDX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1748:ASQ49 RS12305
gene id: 1748:ASQ49_RS12305
uniprot id: A0A806VDY8
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS06660
gene id: 1748:ASQ49_RS06660
uniprot id: A0A142KH99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1748:ASQ49 RS16175
gene id: 1748:ASQ49_RS16175
uniprot id: A0A806VE45
names: Similarity
messages: Belongs to the DDAH family.

1748:ASQ49 RS08045
gene id: 1748:ASQ49_RS08045
uniprot id: A0A806VJ22
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1748:ASQ49 RS16045
gene id: 1748:ASQ49_RS16045
uniprot id: A0A806VDJ8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1748:ASQ49 RS07950
gene id: 1748:ASQ49_RS07950
uniprot id: A0A806VZ49
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1748:ASQ49 RS02710
gene id: 1748:ASQ49_RS02710
uniprot id: A0A806V7Z8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1748:ASQ49 RS05410
gene id: 1748:ASQ49_RS05410
uniprot id: A0A806V919
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1748:ASQ49 RS04105
gene id: 1748:ASQ49_RS04105
uniprot id: A0A806V8Q8
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS09735
gene id: 1748:ASQ49_RS09735
uniprot id: A0A142KFU8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1748:ASQ49 RS05580
gene id: 1748:ASQ49_RS05580
uniprot id: A0A142KHR4
names: Similarity
messages: Belongs to the citrate synthase family.

1748:ASQ49 RS05605
gene id: 1748:ASQ49_RS05605
uniprot id: A0A142KHR0
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

1748:ASQ49 RS09350
gene id: 1748:ASQ49_RS09350
uniprot id: A0A142KG17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1748:ASQ49 RS11240
gene id: 1748:ASQ49_RS11240
uniprot id: A0A142KF81
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1748:ASQ49 RS04515
gene id: 1748:ASQ49_RS04515
uniprot id: A0A806VGV1
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1748:ASQ49 RS12505
gene id: 1748:ASQ49_RS12505
uniprot id: A0A806VCM0
names: Subcellular Location Annotation
messages: Cytoplasm

1748:ASQ49 RS10240
gene id: 1748:ASQ49_RS10240
uniprot id: A0A806VZU8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1748:ASQ49 RS10740
gene id: 1748:ASQ49_RS10740
uniprot id: A0A142KFG4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1748:ASQ49 RS06450
gene id: 1748:ASQ49_RS06450
uniprot id: A0A806V9S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1748:ASQ49 RS10020
gene id: 1748:ASQ49_RS10020
uniprot id: A0A806VBL3
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS10865
gene id: 1748:ASQ49_RS10865
uniprot id: A0A806VBX4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS10535
gene id: 1748:ASQ49_RS10535
uniprot id: A0A806VGM3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1748:ASQ49 RS16400
gene id: 1748:ASQ49_RS16400
uniprot id: A0A806W1N3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1748:ASQ49 RS11555
gene id: 1748:ASQ49_RS11555
uniprot id: A0A806VBT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1748:ASQ49 RS13940
gene id: 1748:ASQ49_RS13940
uniprot id: A0A806VK89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

1748:ASQ49 RS12545
gene id: 1748:ASQ49_RS12545
uniprot id: A0A806VH74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1748:ASQ49 RS03650
gene id: 1748:ASQ49_RS03650
uniprot id: A0A806VGJ6
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS00255
gene id: 1748:ASQ49_RS00255
uniprot id: A0A142KMD6
names: Similarity
messages: Belongs to the thioredoxin family.

1748:ASQ49 RS16035
gene id: 1748:ASQ49_RS16035
uniprot id: A0A806VSJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1748:ASQ49 RS03260
gene id: 1748:ASQ49_RS03260
uniprot id: A0A806VA50
names: Similarity
messages: Belongs to the sulfatase family.

1748:ASQ49 RS09365
gene id: 1748:ASQ49_RS09365
uniprot id: A0A806VB21
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1748:ASQ49 RS10940
gene id: 1748:ASQ49_RS10940
uniprot id: A0A806VBP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1748:ASQ49 RS03710
gene id: 1748:ASQ49_RS03710
uniprot id: A0A806W239
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1748:ASQ49 RS16295
gene id: 1748:ASQ49_RS16295
uniprot id: A0A806VSM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1748:ASQ49 RS01215
gene id: 1748:ASQ49_RS01215
uniprot id: A0A806VCZ0
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1748:ASQ49 RS11280
gene id: 1748:ASQ49_RS11280
uniprot id: A0A806VC37
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1748:ASQ49 RS10080
gene id: 1748:ASQ49_RS10080
uniprot id: A0A142KFP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1748:ASQ49 RS06810
gene id: 1748:ASQ49_RS06810
uniprot id: A0A806V9M1
names: Similarity
messages: Belongs to the peptidase S9C family.

1748:ASQ49 RS10250
gene id: 1748:ASQ49_RS10250
uniprot id: A0A806VJ70
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1748:ASQ49 RS14335
gene id: 1748:ASQ49_RS14335
uniprot id: A0A806W258
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS00845
gene id: 1748:ASQ49_RS00845
uniprot id: A0A806V788
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS08875
gene id: 1748:ASQ49_RS08875
uniprot id: A0A806VPE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1748:ASQ49 RS10725
gene id: 1748:ASQ49_RS10725
uniprot id: A0A806VIU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1748:ASQ49 RS14890
gene id: 1748:ASQ49_RS14890
uniprot id: A0A142KKY1
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1748:ASQ49 RS15765
gene id: 1748:ASQ49_RS15765
uniprot id: A0A806VDR2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1748:ASQ49 RS09620
gene id: 1748:ASQ49_RS09620
uniprot id: A0A142KFW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1748:ASQ49 RS10770
gene id: 1748:ASQ49_RS10770
uniprot id: A0A806VZZ1
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS12815
gene id: 1748:ASQ49_RS12815
uniprot id: A0A142KEF3
names: Similarity
messages: Belongs to the peptidase T1A family.

1748:ASQ49 RS06040
gene id: 1748:ASQ49_RS06040
uniprot id: A0A806VN60
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1748:ASQ49 RS09745
gene id: 1748:ASQ49_RS09745
uniprot id: A0A806VCV2
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1748:ASQ49 RS06615
gene id: 1748:ASQ49_RS06615
uniprot id: A0A806VYR2
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1748:ASQ49 RS13280
gene id: 1748:ASQ49_RS13280
uniprot id: A0A806W0R2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS08390
gene id: 1748:ASQ49_RS08390
uniprot id: A0A806VC67
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1748:ASQ49 RS08915
gene id: 1748:ASQ49_RS08915
uniprot id: A0A806VCG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1748:ASQ49 RS12285
gene id: 1748:ASQ49_RS12285
uniprot id: A0A806VBV1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1748:ASQ49 RS00935
gene id: 1748:ASQ49_RS00935
uniprot id: A0A806V7N4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1748:ASQ49 RS09465
gene id: 1748:ASQ49_RS09465
uniprot id: A0A142KFZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1748:ASQ49 RS02260
gene id: 1748:ASQ49_RS02260
uniprot id: A0A806V9Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS13995
gene id: 1748:ASQ49_RS13995
uniprot id: A0A806W0Y5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1748:ASQ49 RS08335
gene id: 1748:ASQ49_RS08335
uniprot id: A0A806VAX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1748:ASQ49 RS03135
gene id: 1748:ASQ49_RS03135
uniprot id: A0A806V8P2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1748:ASQ49 RS12725
gene id: 1748:ASQ49_RS12725
uniprot id: A0A142KED7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1748:ASQ49 RS10050
gene id: 1748:ASQ49_RS10050
uniprot id: A0A142KFQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1748:ASQ49 RS09940
gene id: 1748:ASQ49_RS09940
uniprot id: A0A142KFR6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1748:ASQ49 RS00720
gene id: 1748:ASQ49_RS00720
uniprot id: A0A806VWV2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS14930
gene id: 1748:ASQ49_RS14930
uniprot id: A0A806VKQ8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1748:ASQ49 RS07000
gene id: 1748:ASQ49_RS07000
uniprot id: A0A806VHH1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1748:ASQ49 RS12555
gene id: 1748:ASQ49_RS12555
uniprot id: A0A142KEA6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1748:ASQ49 RS02420
gene id: 1748:ASQ49_RS02420
uniprot id: A0A806VXQ5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS00800
gene id: 1748:ASQ49_RS00800
uniprot id: A0A142KJR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1748:ASQ49 RS12550
gene id: 1748:ASQ49_RS12550
uniprot id: A0A142KEA5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1748:ASQ49 RS16095
gene id: 1748:ASQ49_RS16095
uniprot id: A0A142KKE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1748:ASQ49 RS14175
gene id: 1748:ASQ49_RS14175
uniprot id: A0A806VCP8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1748:ASQ49 RS06490
gene id: 1748:ASQ49_RS06490
uniprot id: A0A806VHD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS01805
gene id: 1748:ASQ49_RS01805
uniprot id: A0A806VD94
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS15380
gene id: 1748:ASQ49_RS15380
uniprot id: A0A142KKP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS03275
gene id: 1748:ASQ49_RS03275
uniprot id: A0A806V8L6
names: Similarity
messages: Belongs to the sulfatase family.

1748:ASQ49 RS05370
gene id: 1748:ASQ49_RS05370
uniprot id: A0A806V9N2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS11700
gene id: 1748:ASQ49_RS11700
uniprot id: A0A142KDX1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1748:ASQ49 RS05320
gene id: 1748:ASQ49_RS05320
uniprot id: A0A806VYM0
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1748:ASQ49 RS13125
gene id: 1748:ASQ49_RS13125
uniprot id: A0A806VR69
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS05635
gene id: 1748:ASQ49_RS05635
uniprot id: A0A806VH62
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1748:ASQ49 RS13060
gene id: 1748:ASQ49_RS13060
uniprot id: A0A806VC70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1748:ASQ49 RS09240
gene id: 1748:ASQ49_RS09240
uniprot id: A0A142KG38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1748:ASQ49 RS06025
gene id: 1748:ASQ49_RS06025
uniprot id: A0A142KHI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1748:ASQ49 RS09440
gene id: 1748:ASQ49_RS09440
uniprot id: A0A142KG01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1748:ASQ49 RS01230
gene id: 1748:ASQ49_RS01230
uniprot id: A0A142KJJ4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1748:ASQ49 RS10485
gene id: 1748:ASQ49_RS10485
uniprot id: A0A806VBS2
names: Similarity
messages: Belongs to the FPG family.

1748:ASQ49 RS09340
gene id: 1748:ASQ49_RS09340
uniprot id: A0A142KG19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1748:ASQ49 RS05070
gene id: 1748:ASQ49_RS05070
uniprot id: A0A1P8TZC0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1748:ASQ49 RS00580
gene id: 1748:ASQ49_RS00580
uniprot id: A0A806V759
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1748:ASQ49 RS09255
gene id: 1748:ASQ49_RS09255
uniprot id: A0A142KG35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1748:ASQ49 RS08025
gene id: 1748:ASQ49_RS08025
uniprot id: A0A806VZ56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS12445
gene id: 1748:ASQ49_RS12445
uniprot id: A0A806VCK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1748:ASQ49 RS03970
gene id: 1748:ASQ49_RS03970
uniprot id: A0A806VM97
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1748:ASQ49 RS03270
gene id: 1748:ASQ49_RS03270
uniprot id: A0A806VY04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1748:ASQ49 RS02485
gene id: 1748:ASQ49_RS02485
uniprot id: A0A142KIW8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1748:ASQ49 RS13660
gene id: 1748:ASQ49_RS13660
uniprot id: A0A806VCY2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS01815
gene id: 1748:ASQ49_RS01815
uniprot id: A0A806V9I2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1748:ASQ49 RS11210
gene id: 1748:ASQ49_RS11210
uniprot id: A0A142KF85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1748:ASQ49 RS10045
gene id: 1748:ASQ49_RS10045
uniprot id: A0A806VPW6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1748:ASQ49 RS12585
gene id: 1748:ASQ49_RS12585
uniprot id: A0A806VGJ5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1748:ASQ49 RS16130
gene id: 1748:ASQ49_RS16130
uniprot id: A0A142KKD9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1748:ASQ49 RS12270
gene id: 1748:ASQ49_RS12270
uniprot id: A0A142KE60
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1748:ASQ49 RS11885
gene id: 1748:ASQ49_RS11885
uniprot id: A0A806VF55
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1748:ASQ49 RS09485
gene id: 1748:ASQ49_RS09485
uniprot id: A0A806VZL7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS01495
gene id: 1748:ASQ49_RS01495
uniprot id: A0A806VFR9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1748:ASQ49 RS01410
gene id: 1748:ASQ49_RS01410
uniprot id: A0A806V7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS16300
gene id: 1748:ASQ49_RS16300
uniprot id: A0A806VLC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1748:ASQ49 RS15140
gene id: 1748:ASQ49_RS15140
uniprot id: A0A142KKT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS04695
gene id: 1748:ASQ49_RS04695
uniprot id: A0A806VMK5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1748:ASQ49 RS11330
gene id: 1748:ASQ49_RS11330
uniprot id: A0A806VGW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1748:ASQ49 RS03195
gene id: 1748:ASQ49_RS03195
uniprot id: A0A806V8C3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1748:ASQ49 RS04825
gene id: 1748:ASQ49_RS04825
uniprot id: A0A806V9F1
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1748:ASQ49 RS12070
gene id: 1748:ASQ49_RS12070
uniprot id: A0A142KLE3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1748:ASQ49 RS09075
gene id: 1748:ASQ49_RS09075
uniprot id: A0A142KLQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1748:ASQ49 RS09150
gene id: 1748:ASQ49_RS09150
uniprot id: A0A142KG53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1748:ASQ49 RS12220
gene id: 1748:ASQ49_RS12220
uniprot id: A0A142KE50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1748:ASQ49 RS13910
gene id: 1748:ASQ49_RS13910
uniprot id: A0A806VD87
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1748:ASQ49 RS09310
gene id: 1748:ASQ49_RS09310
uniprot id: A0A806VB11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1748:ASQ49 RS02715
gene id: 1748:ASQ49_RS02715
uniprot id: A0A806VDQ4
names: Similarity
messages: Belongs to the HsdR family.

1748:ASQ49 RS12750
gene id: 1748:ASQ49_RS12750
uniprot id: A0A142KEE2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1748:ASQ49 RS03500
gene id: 1748:ASQ49_RS03500
uniprot id: A0A806V8G5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1748:ASQ49 RS05535
gene id: 1748:ASQ49_RS05535
uniprot id: A0A806VEV6
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS09795
gene id: 1748:ASQ49_RS09795
uniprot id: A0A142KFU0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1748:ASQ49 RS05685
gene id: 1748:ASQ49_RS05685
uniprot id: A0A806VT27
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1748:ASQ49 RS04385
gene id: 1748:ASQ49_RS04385
uniprot id: A0A806VY27
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1748:ASQ49 RS08255
gene id: 1748:ASQ49_RS08255
uniprot id: A0A806VP24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1748:ASQ49 RS15515
gene id: 1748:ASQ49_RS15515
uniprot id: A0A142KMG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1748:ASQ49 RS03145
gene id: 1748:ASQ49_RS03145
uniprot id: A0A806V8J8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1748:ASQ49 RS06495
gene id: 1748:ASQ49_RS06495
uniprot id: A0A806V9I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS06820
gene id: 1748:ASQ49_RS06820
uniprot id: A0A806V9W9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1748:ASQ49 RS03050
gene id: 1748:ASQ49_RS03050
uniprot id: A0A806VDV8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1748:ASQ49 RS15285
gene id: 1748:ASQ49_RS15285
uniprot id: A0A142KKR5
names: Similarity
messages: Belongs to the peptidase M24B family.

1748:ASQ49 RS15175
gene id: 1748:ASQ49_RS15175
uniprot id: A0A806VF99
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS14160
gene id: 1748:ASQ49_RS14160
uniprot id: A0A806W108
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1748:ASQ49 RS15625
gene id: 1748:ASQ49_RS15625
uniprot id: A0A142KKK8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1748:ASQ49 RS13945
gene id: 1748:ASQ49_RS13945
uniprot id: A0A806VCK4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1748:ASQ49 RS08540
gene id: 1748:ASQ49_RS08540
uniprot id: A0A142KGE6
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS13270
gene id: 1748:ASQ49_RS13270
uniprot id: A0A142KEN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1748:ASQ49 RS10230
gene id: 1748:ASQ49_RS10230
uniprot id: A0A806W040
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1748:ASQ49 RS11490
gene id: 1748:ASQ49_RS11490
uniprot id: A0A142KDU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1748:ASQ49 RS12325
gene id: 1748:ASQ49_RS12325
uniprot id: A0A806W0R4
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1748:ASQ49 RS09895
gene id: 1748:ASQ49_RS09895
uniprot id: A0A806VB99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1748:ASQ49 RS16250
gene id: 1748:ASQ49_RS16250
uniprot id: A0A806VE92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1748:ASQ49 RS15035
gene id: 1748:ASQ49_RS15035
uniprot id: A0A806VKT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS06390
gene id: 1748:ASQ49_RS06390
uniprot id: A0A806VF67
names: Similarity
messages: Belongs to the FGGY kinase family.

1748:ASQ49 RS00210
gene id: 1748:ASQ49_RS00210
uniprot id: A0A142KMD9
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS08420
gene id: 1748:ASQ49_RS08420
uniprot id: A0A142KGG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1748:ASQ49 RS01960
gene id: 1748:ASQ49_RS01960
uniprot id: A0A806VFX6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1748:ASQ49 RS11250
gene id: 1748:ASQ49_RS11250
uniprot id: A0A3Q9CN68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1748:ASQ49 RS00165
gene id: 1748:ASQ49_RS00165
uniprot id: A0A806VKH8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1748:ASQ49 RS09145
gene id: 1748:ASQ49_RS09145
uniprot id: A0A806VES1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1748:ASQ49 RS11410
gene id: 1748:ASQ49_RS11410
uniprot id: A0A142KF58
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1748:ASQ49 RS09265
gene id: 1748:ASQ49_RS09265
uniprot id: A0A142KG33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1748:ASQ49 RS14775
gene id: 1748:ASQ49_RS14775
uniprot id: A0A806VF31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS02425
gene id: 1748:ASQ49_RS02425
uniprot id: A0A142KIX9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1748:ASQ49 RS09695
gene id: 1748:ASQ49_RS09695
uniprot id: A0A806VBH2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1748:ASQ49 RS14645
gene id: 1748:ASQ49_RS14645
uniprot id: A0A806VHS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1748:ASQ49 RS05195
gene id: 1748:ASQ49_RS05195
uniprot id: A0A806VYK4
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS05095
gene id: 1748:ASQ49_RS05095
uniprot id: A0A1P8TZB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1748:ASQ49 RS14025
gene id: 1748:ASQ49_RS14025
uniprot id: A0A142KDS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS08080
gene id: 1748:ASQ49_RS08080
uniprot id: A0A806VAT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1748:ASQ49 RS00865
gene id: 1748:ASQ49_RS00865
uniprot id: A0A806V7Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1748:ASQ49 RS10235
gene id: 1748:ASQ49_RS10235
uniprot id: A0A806VBE4
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS12795
gene id: 1748:ASQ49_RS12795
uniprot id: A0A806W0K6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1748:ASQ49 RS00195
gene id: 1748:ASQ49_RS00195
uniprot id: A0A806V7G4
names: Similarity
messages: Belongs to the UDPGP type 1 family.

1748:ASQ49 RS00795
gene id: 1748:ASQ49_RS00795
uniprot id: A0A806V7C4
names: Subcellular Location Annotation
messages: Cytoplasm

1748:ASQ49 RS09115
gene id: 1748:ASQ49_RS09115
uniprot id: A0A142KG58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1748:ASQ49 RS01560
gene id: 1748:ASQ49_RS01560
uniprot id: A0A806V7N5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1748:ASQ49 RS13560
gene id: 1748:ASQ49_RS13560
uniprot id: A0A806VRD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1748:ASQ49 RS06205
gene id: 1748:ASQ49_RS06205
uniprot id: A0A806VN77
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1748:ASQ49 RS12570
gene id: 1748:ASQ49_RS12570
uniprot id: A0A806VCE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1748:ASQ49 RS01640
gene id: 1748:ASQ49_RS01640
uniprot id: A0A806VXF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1748:ASQ49 RS07845
gene id: 1748:ASQ49_RS07845
uniprot id: A0A142KGQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1748:ASQ49 RS01985
gene id: 1748:ASQ49_RS01985
uniprot id: A0A806V9K5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS13365
gene id: 1748:ASQ49_RS13365
uniprot id: A0A806VRA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1748:ASQ49 RS13900
gene id: 1748:ASQ49_RS13900
uniprot id: A0A806W254
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1748:ASQ49 RS04870
gene id: 1748:ASQ49_RS04870
uniprot id: A0A806V924
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1748:ASQ49 RS15505
gene id: 1748:ASQ49_RS15505
uniprot id: A0A806VL09
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1748:ASQ49 RS02440
gene id: 1748:ASQ49_RS02440
uniprot id: A0A142KIX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS01145
gene id: 1748:ASQ49_RS01145
uniprot id: A0A806V7H5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.

1748:ASQ49 RS01250
gene id: 1748:ASQ49_RS01250
uniprot id: A0A142KJJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1748:ASQ49 RS08870
gene id: 1748:ASQ49_RS08870
uniprot id: A0A806VZG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1748:ASQ49 RS13960
gene id: 1748:ASQ49_RS13960
uniprot id: A0A142KF55
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1748:ASQ49 RS08945
gene id: 1748:ASQ49_RS08945
uniprot id: A0A1P8TXM2
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS02220
gene id: 1748:ASQ49_RS02220
uniprot id: A0A806V865
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1748:ASQ49 RS10545
gene id: 1748:ASQ49_RS10545
uniprot id: A0A806VD73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1748:ASQ49 RS14895
gene id: 1748:ASQ49_RS14895
uniprot id: A0A142KKY0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1748:ASQ49 RS00700
gene id: 1748:ASQ49_RS00700
uniprot id: A0A142KJT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS06055
gene id: 1748:ASQ49_RS06055
uniprot id: A0A806VF26
names: Subcellular Location Annotation
messages: Cell membrane

1748:ASQ49 RS04075
gene id: 1748:ASQ49_RS04075
uniprot id: A0A806V8W9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1748:ASQ49 RS06850
gene id: 1748:ASQ49_RS06850
uniprot id: A0A142KLX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1748:ASQ49 RS03010
gene id: 1748:ASQ49_RS03010
uniprot id: A0A806V8M5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1748:ASQ49 RS08465
gene id: 1748:ASQ49_RS08465
uniprot id: A0A806VAN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1748:ASQ49 RS11705
gene id: 1748:ASQ49_RS11705
uniprot id: A0A142KDX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1748:ASQ49 RS08530
gene id: 1748:ASQ49_RS08530
uniprot id: A0A142KGE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS01740
gene id: 1748:ASQ49_RS01740
uniprot id: A0A142KJA5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1748:ASQ49 RS06280
gene id: 1748:ASQ49_RS06280
uniprot id: A0A806VF50
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1748:ASQ49 RS07750
gene id: 1748:ASQ49_RS07750
uniprot id: A0A806VAA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS15595
gene id: 1748:ASQ49_RS15595
uniprot id: A0A806VI53
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1748:ASQ49 RS01305
gene id: 1748:ASQ49_RS01305
uniprot id: A0A806VL12
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1748:ASQ49 RS18350
gene id: 1748:ASQ49_RS18350
uniprot id: A0A806VEW4
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1748:ASQ49 RS13840
gene id: 1748:ASQ49_RS13840
uniprot id: A0A142KF37
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1748:ASQ49 RS06000
gene id: 1748:ASQ49_RS06000
uniprot id: A0A806V9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1748:ASQ49 RS14110
gene id: 1748:ASQ49_RS14110
uniprot id: A0A142KDQ9
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS04850
gene id: 1748:ASQ49_RS04850
uniprot id: A0A806VGZ4
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1748:ASQ49 RS16025
gene id: 1748:ASQ49_RS16025
uniprot id: A0A142KKF4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1748:ASQ49 RS13905
gene id: 1748:ASQ49_RS13905
uniprot id: A0A806VEN9
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1748:ASQ49 RS01510
gene id: 1748:ASQ49_RS01510
uniprot id: A0A806V7M5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS08470
gene id: 1748:ASQ49_RS08470
uniprot id: A0A142KGG0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1748:ASQ49 RS12695
gene id: 1748:ASQ49_RS12695
uniprot id: A0A142KED2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS09455
gene id: 1748:ASQ49_RS09455
uniprot id: A0A142KFZ8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1748:ASQ49 RS12930
gene id: 1748:ASQ49_RS12930
uniprot id: A0A806VR43
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1748:ASQ49 RS02125
gene id: 1748:ASQ49_RS02125
uniprot id: A0A806VFZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS11645
gene id: 1748:ASQ49_RS11645
uniprot id: A0A142KDW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1748:ASQ49 RS14605
gene id: 1748:ASQ49_RS14605
uniprot id: A0A142KL31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1748:ASQ49 RS01955
gene id: 1748:ASQ49_RS01955
uniprot id: A0A806VLB2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1748:ASQ49 RS07240
gene id: 1748:ASQ49_RS07240
uniprot id: A0A806VNL1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS06165
gene id: 1748:ASQ49_RS06165
uniprot id: A0A806VA12
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS00735
gene id: 1748:ASQ49_RS00735
uniprot id: A0A806V779
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1748:ASQ49 RS09705
gene id: 1748:ASQ49_RS09705
uniprot id: A0A142KFV4
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS12095
gene id: 1748:ASQ49_RS12095
uniprot id: A0A806VCE9
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS05855
gene id: 1748:ASQ49_RS05855
uniprot id: A0A806VEZ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1748:ASQ49 RS00330
gene id: 1748:ASQ49_RS00330
uniprot id: A0A806VKK3
names: Similarity
messages: Belongs to the CutC family.

1748:ASQ49 RS01575
gene id: 1748:ASQ49_RS01575
uniprot id: A0A142KJD1
names: Similarity
messages: Belongs to the UPF0098 family.

1748:ASQ49 RS04865
gene id: 1748:ASQ49_RS04865
uniprot id: A0A806VEL3
names: Similarity
messages: Belongs to the TPP enzyme family.

1748:ASQ49 RS07020
gene id: 1748:ASQ49_RS07020
uniprot id: A0A806V9Z6
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1748:ASQ49 RS02060
gene id: 1748:ASQ49_RS02060
uniprot id: A0A806V840
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS03280
gene id: 1748:ASQ49_RS03280
uniprot id: A0A806VXR7
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS01430
gene id: 1748:ASQ49_RS01430
uniprot id: A0A806VL31
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS00785
gene id: 1748:ASQ49_RS00785
uniprot id: A0A806V783
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1748:ASQ49 RS08435
gene id: 1748:ASQ49_RS08435
uniprot id: A0A142KGG6
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1748:ASQ49 RS14760
gene id: 1748:ASQ49_RS14760
uniprot id: A0A806VCZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1748:ASQ49 RS15590
gene id: 1748:ASQ49_RS15590
uniprot id: A0A806VDC7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1748:ASQ49 RS10815
gene id: 1748:ASQ49_RS10815
uniprot id: A0A806VBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1748:ASQ49 RS18280
gene id: 1748:ASQ49_RS18280
uniprot id: A0A806W0S1
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS04415
gene id: 1748:ASQ49_RS04415
uniprot id: A0A142KI89
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1748:ASQ49 RS05055
gene id: 1748:ASQ49_RS05055
uniprot id: A0A806VE20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1748:ASQ49 RS02130
gene id: 1748:ASQ49_RS02130
uniprot id: A0A806V7R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS10440
gene id: 1748:ASQ49_RS10440
uniprot id: A0A806VZW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1748:ASQ49 RS14020
gene id: 1748:ASQ49_RS14020
uniprot id: A0A1P8TV94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS11310
gene id: 1748:ASQ49_RS11310
uniprot id: A0A806VQF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS07795
gene id: 1748:ASQ49_RS07795
uniprot id: A0A142KGR4
names: Similarity
messages: Belongs to the P(II) protein family.

1748:ASQ49 RS09925
gene id: 1748:ASQ49_RS09925
uniprot id: A0A142KFR9
names: Similarity
messages: Belongs to the peptidase S51 family.

1748:ASQ49 RS03575
gene id: 1748:ASQ49_RS03575
uniprot id: A0A806VY39
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1748:ASQ49 RS00535
gene id: 1748:ASQ49_RS00535
uniprot id: A0A806V8Y2
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS07995
gene id: 1748:ASQ49_RS07995
uniprot id: A0A806VEA7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1748:ASQ49 RS00475
gene id: 1748:ASQ49_RS00475
uniprot id: A0A806V8X3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1748:ASQ49 RS14155
gene id: 1748:ASQ49_RS14155
uniprot id: A0A806VD58
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

1748:ASQ49 RS05025
gene id: 1748:ASQ49_RS05025
uniprot id: A0A806VMR4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1748:ASQ49 RS07670
gene id: 1748:ASQ49_RS07670
uniprot id: A0A142KGT3
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS11760
gene id: 1748:ASQ49_RS11760
uniprot id: A0A806W091
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1748:ASQ49 RS00365
gene id: 1748:ASQ49_RS00365
uniprot id: A0A806V7J0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1748:ASQ49 RS08700
gene id: 1748:ASQ49_RS08700
uniprot id: A0A806VZD8
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1748:ASQ49 RS03670
gene id: 1748:ASQ49_RS03670
uniprot id: A0A806VAA9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS11205
gene id: 1748:ASQ49_RS11205
uniprot id: A0A142KF86
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1748:ASQ49 RS10860
gene id: 1748:ASQ49_RS10860
uniprot id: A0A806VDB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1748:ASQ49 RS09175
gene id: 1748:ASQ49_RS09175
uniprot id: A0A142KG48
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1748:ASQ49 RS16240
gene id: 1748:ASQ49_RS16240
uniprot id: A0A806VDX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1748:ASQ49 RS01730
gene id: 1748:ASQ49_RS01730
uniprot id: A0A806VD83
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS11730
gene id: 1748:ASQ49_RS11730
uniprot id: A0A142KDX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1748:ASQ49 RS09085
gene id: 1748:ASQ49_RS09085
uniprot id: A0A142KG63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1748:ASQ49 RS09850
gene id: 1748:ASQ49_RS09850
uniprot id: A0A806VPU1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1748:ASQ49 RS09590
gene id: 1748:ASQ49_RS09590
uniprot id: A0A806VZX5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1748:ASQ49 RS03600
gene id: 1748:ASQ49_RS03600
uniprot id: A0A806V8A1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1748:ASQ49 RS05405
gene id: 1748:ASQ49_RS05405
uniprot id: A0A806VH43
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS05085
gene id: 1748:ASQ49_RS05085
uniprot id: A0A142KI14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1748:ASQ49 RS02995
gene id: 1748:ASQ49_RS02995
uniprot id: A0A806VDV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1748:ASQ49 RS14525
gene id: 1748:ASQ49_RS14525
uniprot id: A0A142KMI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1748:ASQ49 RS13380
gene id: 1748:ASQ49_RS13380
uniprot id: A0A142KLH1
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS15975
gene id: 1748:ASQ49_RS15975
uniprot id: A0A806VSI9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1748:ASQ49 RS03605
gene id: 1748:ASQ49_RS03605
uniprot id: A0A142KIM2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1748:ASQ49 RS02240
gene id: 1748:ASQ49_RS02240
uniprot id: A0A806VG14
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1748:ASQ49 RS08905
gene id: 1748:ASQ49_RS08905
uniprot id: A0A806VAT3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1748:ASQ49 RS14745
gene id: 1748:ASQ49_RS14745
uniprot id: A0A142KL07
names: Similarity
messages: Belongs to the YggT family.

1748:ASQ49 RS04860
gene id: 1748:ASQ49_RS04860
uniprot id: A0A806V8T3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1748:ASQ49 RS08995
gene id: 1748:ASQ49_RS08995
uniprot id: A0A806VCH2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1748:ASQ49 RS02435
gene id: 1748:ASQ49_RS02435
uniprot id: A0A806VLI9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1748:ASQ49 RS04330
gene id: 1748:ASQ49_RS04330
uniprot id: A0A806VMF3
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS03870
gene id: 1748:ASQ49_RS03870
uniprot id: A0A806V8M2
names: Similarity
messages: Belongs to the Dps family.

1748:ASQ49 RS02295
gene id: 1748:ASQ49_RS02295
uniprot id: A0A806VLH0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1748:ASQ49 RS14855
gene id: 1748:ASQ49_RS14855
uniprot id: A0A806W193
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1748:ASQ49 RS04000
gene id: 1748:ASQ49_RS04000
uniprot id: A0A806V8P0
names: Similarity
messages: Belongs to the acylphosphatase family.

1748:ASQ49 RS01000
gene id: 1748:ASQ49_RS01000
uniprot id: A0A806VFK7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1748:ASQ49 RS03430
gene id: 1748:ASQ49_RS03430
uniprot id: A0A806VE10
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1748:ASQ49 RS15055
gene id: 1748:ASQ49_RS15055
uniprot id: A0A806VF80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1748:ASQ49 RS09050
gene id: 1748:ASQ49_RS09050
uniprot id: A0A806VAJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1748:ASQ49 RS07090
gene id: 1748:ASQ49_RS07090
uniprot id: A0A806VA05
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1748:ASQ49 RS10515
gene id: 1748:ASQ49_RS10515
uniprot id: A0A806VQ33
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1748:ASQ49 RS08430
gene id: 1748:ASQ49_RS08430
uniprot id: A0A142KGG7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1748:ASQ49 RS11340
gene id: 1748:ASQ49_RS11340
uniprot id: A0A806VDJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1748:ASQ49 RS07170
gene id: 1748:ASQ49_RS07170
uniprot id: A0A806VYW8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1748:ASQ49 RS08505
gene id: 1748:ASQ49_RS08505
uniprot id: A0A806VAZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1748:ASQ49 RS09285
gene id: 1748:ASQ49_RS09285
uniprot id: A0A806VG72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS05075
gene id: 1748:ASQ49_RS05075
uniprot id: A0A806VIU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS09415
gene id: 1748:ASQ49_RS09415
uniprot id: A0A806VZW0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS14790
gene id: 1748:ASQ49_RS14790
uniprot id: A0A806W1L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS15965
gene id: 1748:ASQ49_RS15965
uniprot id: A0A806W1K5
names: Similarity
messages: Belongs to the peptidase M18 family.

1748:ASQ49 RS15105
gene id: 1748:ASQ49_RS15105
uniprot id: A0A806VHZ9
names: Similarity
messages: Belongs to the PspA/IM30 family.

1748:ASQ49 RS08325
gene id: 1748:ASQ49_RS08325
uniprot id: A0A142KGI5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS06385
gene id: 1748:ASQ49_RS06385
uniprot id: A0A806V9G4
names: Similarity
messages: Belongs to the FGGY kinase family.

1748:ASQ49 RS14865
gene id: 1748:ASQ49_RS14865
uniprot id: A0A806VS18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS01735
gene id: 1748:ASQ49_RS01735
uniprot id: A0A806V7Q7
names: Similarity
messages: Belongs to the UPF0045 family.

1748:ASQ49 RS01630
gene id: 1748:ASQ49_RS01630
uniprot id: A0A806V812
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1748:ASQ49 RS00230
gene id: 1748:ASQ49_RS00230
uniprot id: A0A142KK75
names: Similarity
messages: Belongs to the TPP enzyme family.

1748:ASQ49 RS10900
gene id: 1748:ASQ49_RS10900
uniprot id: A0A806VIX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1748:ASQ49 RS07660
gene id: 1748:ASQ49_RS07660
uniprot id: A0A142KGT4
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1748:ASQ49 RS10685
gene id: 1748:ASQ49_RS10685
uniprot id: A0A806VD90
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS01235
gene id: 1748:ASQ49_RS01235
uniprot id: A0A806VX96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1748:ASQ49 RS11125
gene id: 1748:ASQ49_RS11125
uniprot id: A0A806W028
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1748:ASQ49 RS10095
gene id: 1748:ASQ49_RS10095
uniprot id: A0A806VZT4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1748:ASQ49 RS08850
gene id: 1748:ASQ49_RS08850
uniprot id: A0A142KG96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1748:ASQ49 RS03100
gene id: 1748:ASQ49_RS03100
uniprot id: A0A806VGC6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1748:ASQ49 RS15395
gene id: 1748:ASQ49_RS15395
uniprot id: A0A806VS97
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1748:ASQ49 RS09945
gene id: 1748:ASQ49_RS09945
uniprot id: A0A806VEU1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1748:ASQ49 RS01210
gene id: 1748:ASQ49_RS01210
uniprot id: A0A806V7D9
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

1748:ASQ49 RS00080
gene id: 1748:ASQ49_RS00080
uniprot id: A0A806V7E4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1748:ASQ49 RS14170
gene id: 1748:ASQ49_RS14170
uniprot id: A0A142KDP7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1748:ASQ49 RS08370
gene id: 1748:ASQ49_RS08370
uniprot id: A0A806VAA1
names: Similarity
messages: Belongs to the CsoR family.

1748:ASQ49 RS00445
gene id: 1748:ASQ49_RS00445
uniprot id: A0A806VKM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1748:ASQ49 RS08170
gene id: 1748:ASQ49_RS08170
uniprot id: A0A806VZG2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1748:ASQ49 RS04305
gene id: 1748:ASQ49_RS04305
uniprot id: A0A806V970
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

1748:ASQ49 RS15060
gene id: 1748:ASQ49_RS15060
uniprot id: A0A806VDR5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS01965
gene id: 1748:ASQ49_RS01965
uniprot id: A0A806V7P5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1748:ASQ49 RS13110
gene id: 1748:ASQ49_RS13110
uniprot id: A0A806VCN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1748:ASQ49 RS12015
gene id: 1748:ASQ49_RS12015
uniprot id: A0A142KE17
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1748:ASQ49 RS02445
gene id: 1748:ASQ49_RS02445
uniprot id: A0A806V7V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS11470
gene id: 1748:ASQ49_RS11470
uniprot id: A0A142KDT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS09880
gene id: 1748:ASQ49_RS09880
uniprot id: A0A142KFS5
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1748:ASQ49 RS01660
gene id: 1748:ASQ49_RS01660
uniprot id: A0A142KJB8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1748:ASQ49 RS10100
gene id: 1748:ASQ49_RS10100
uniprot id: A0A142KFP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1748:ASQ49 RS08155
gene id: 1748:ASQ49_RS08155
uniprot id: A0A806VEB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1748:ASQ49 RS08410
gene id: 1748:ASQ49_RS08410
uniprot id: A0A806VAM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1748:ASQ49 RS13725
gene id: 1748:ASQ49_RS13725
uniprot id: A0A142KF19
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1748:ASQ49 RS12735
gene id: 1748:ASQ49_RS12735
uniprot id: A0A806VCH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1748:ASQ49 RS11080
gene id: 1748:ASQ49_RS11080
uniprot id: A0A142KFA8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1748:ASQ49 RS16360
gene id: 1748:ASQ49_RS16360
uniprot id: A0A806VDM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1748:ASQ49 RS13615
gene id: 1748:ASQ49_RS13615
uniprot id: A0A142KF00
names: Similarity
messages: Belongs to the fructosamine kinase family.

1748:ASQ49 RS14610
gene id: 1748:ASQ49_RS14610
uniprot id: A0A806VDI8
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1748:ASQ49 RS04765
gene id: 1748:ASQ49_RS04765
uniprot id: A0A806V903
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1748:ASQ49 RS15460
gene id: 1748:ASQ49_RS15460
uniprot id: A0A806VDA8
names: Similarity
messages: Belongs to the ribulokinase family.

1748:ASQ49 RS08135
gene id: 1748:ASQ49_RS08135
uniprot id: A0A806VFT9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1748:ASQ49 RS11215
gene id: 1748:ASQ49_RS11215
uniprot id: A0A142KF84
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1748:ASQ49 RS15070
gene id: 1748:ASQ49_RS15070
uniprot id: A0A806W1Q4
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

1748:ASQ49 RS13740
gene id: 1748:ASQ49_RS13740
uniprot id: A0A806VK56
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1748:ASQ49 RS08285
gene id: 1748:ASQ49_RS08285
uniprot id: A0A806VAW0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1748:ASQ49 RS12535
gene id: 1748:ASQ49_RS12535
uniprot id: A0A142KEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1748:ASQ49 RS01150
gene id: 1748:ASQ49_RS01150
uniprot id: A0A806V978
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1748:ASQ49 RS09200
gene id: 1748:ASQ49_RS09200
uniprot id: A0A142KG43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1748:ASQ49 RS12460
gene id: 1748:ASQ49_RS12460
uniprot id: A0A806VEM8
names: Similarity
messages: Belongs to the glutamate synthase family.

1748:ASQ49 RS01120
gene id: 1748:ASQ49_RS01120
uniprot id: A0A806VX02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS09250
gene id: 1748:ASQ49_RS09250
uniprot id: A0A142KG36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1748:ASQ49 RS02405
gene id: 1748:ASQ49_RS02405
uniprot id: A0A806V9S3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1748:ASQ49 RS08725
gene id: 1748:ASQ49_RS08725
uniprot id: A0A142KGB6
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

1748:ASQ49 RS05115
gene id: 1748:ASQ49_RS05115
uniprot id: A0A806VAX6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1748:ASQ49 RS00390
gene id: 1748:ASQ49_RS00390
uniprot id: A0A142KJZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1748:ASQ49 RS05575
gene id: 1748:ASQ49_RS05575
uniprot id: A0A806VH56
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1748:ASQ49 RS10580
gene id: 1748:ASQ49_RS10580
uniprot id: A0A806VJ79
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS02015
gene id: 1748:ASQ49_RS02015
uniprot id: A0A806VDV5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1748:ASQ49 RS13580
gene id: 1748:ASQ49_RS13580
uniprot id: A0A142KEZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1748:ASQ49 RS01285
gene id: 1748:ASQ49_RS01285
uniprot id: A0A806VXA0
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1748:ASQ49 RS11720
gene id: 1748:ASQ49_RS11720
uniprot id: A0A806VJ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1748:ASQ49 RS09570
gene id: 1748:ASQ49_RS09570
uniprot id: A0A806VGA9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1748:ASQ49 RS04535
gene id: 1748:ASQ49_RS04535
uniprot id: A0A1P8TZS9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS12775
gene id: 1748:ASQ49_RS12775
uniprot id: A0A142KEE7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1748:ASQ49 RS12540
gene id: 1748:ASQ49_RS12540
uniprot id: A0A142KEA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1748:ASQ49 RS09400
gene id: 1748:ASQ49_RS09400
uniprot id: A0A142KG08
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS12745
gene id: 1748:ASQ49_RS12745
uniprot id: A0A806VR17
names: Similarity
messages: Belongs to the FPG family.

1748:ASQ49 RS09280
gene id: 1748:ASQ49_RS09280
uniprot id: A0A806VAM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1748:ASQ49 RS09475
gene id: 1748:ASQ49_RS09475
uniprot id: A0A806VZW3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1748:ASQ49 RS16285
gene id: 1748:ASQ49_RS16285
uniprot id: A0A806VE55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1748:ASQ49 RS11735
gene id: 1748:ASQ49_RS11735
uniprot id: A0A806VBV7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1748:ASQ49 RS11165
gene id: 1748:ASQ49_RS11165
uniprot id: A0A806VC21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1748:ASQ49 RS16305
gene id: 1748:ASQ49_RS16305
uniprot id: A0A806VDL9
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS07900
gene id: 1748:ASQ49_RS07900
uniprot id: A0A806VZ43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

1748:ASQ49 RS15925
gene id: 1748:ASQ49_RS15925
uniprot id: A0A806VL76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1748:ASQ49 RS04045
gene id: 1748:ASQ49_RS04045
uniprot id: A0A806VE93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1748:ASQ49 RS11795
gene id: 1748:ASQ49_RS11795
uniprot id: A0A806VJB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1748:ASQ49 RS07390
gene id: 1748:ASQ49_RS07390
uniprot id: A0A142KGX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1748:ASQ49 RS12820
gene id: 1748:ASQ49_RS12820
uniprot id: A0A142KEF4
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1748:ASQ49 RS15420
gene id: 1748:ASQ49_RS15420
uniprot id: A0A142KKP2
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1748:ASQ49 RS08120
gene id: 1748:ASQ49_RS08120
uniprot id: A0A806VP03
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS12065
gene id: 1748:ASQ49_RS12065
uniprot id: A0A142KLE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1748:ASQ49 RS06380
gene id: 1748:ASQ49_RS06380
uniprot id: A0A806VLY7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1748:ASQ49 RS01265
gene id: 1748:ASQ49_RS01265
uniprot id: A0A806VCZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1748:ASQ49 RS12685
gene id: 1748:ASQ49_RS12685
uniprot id: A0A806VCG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1748:ASQ49 RS12230
gene id: 1748:ASQ49_RS12230
uniprot id: A0A142KE52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1748:ASQ49 RS07210
gene id: 1748:ASQ49_RS07210
uniprot id: A0A806VBN4
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS07455
gene id: 1748:ASQ49_RS07455
uniprot id: A0A142KGW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS11405
gene id: 1748:ASQ49_RS11405
uniprot id: A0A142KLJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1748:ASQ49 RS07850
gene id: 1748:ASQ49_RS07850
uniprot id: A0A806VNW3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS12560
gene id: 1748:ASQ49_RS12560
uniprot id: A0A1P8TW19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1748:ASQ49 RS06255
gene id: 1748:ASQ49_RS06255
uniprot id: A0A806VYM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1748:ASQ49 RS13370
gene id: 1748:ASQ49_RS13370
uniprot id: A0A806VK01
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1748:ASQ49 RS06560
gene id: 1748:ASQ49_RS06560
uniprot id: A0A142KHB0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1748:ASQ49 RS04035
gene id: 1748:ASQ49_RS04035
uniprot id: A0A142KIE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1748:ASQ49 RS11995
gene id: 1748:ASQ49_RS11995
uniprot id: A0A806VBP9
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS05435
gene id: 1748:ASQ49_RS05435
uniprot id: A0A142KM17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1748:ASQ49 RS15245
gene id: 1748:ASQ49_RS15245
uniprot id: A0A806VDU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1748:ASQ49 RS00415
gene id: 1748:ASQ49_RS00415
uniprot id: A0A806V8W5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1748:ASQ49 RS00560
gene id: 1748:ASQ49_RS00560
uniprot id: A0A806VWS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1748:ASQ49 RS16375
gene id: 1748:ASQ49_RS16375
uniprot id: A0A142KKA8
names: Similarity
messages: Belongs to the peptidase C56 family.

1748:ASQ49 RS05030
gene id: 1748:ASQ49_RS05030
uniprot id: A0A806VH08
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1748:ASQ49 RS05510
gene id: 1748:ASQ49_RS05510
uniprot id: A0A142KHS7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1748:ASQ49 RS08835
gene id: 1748:ASQ49_RS08835
uniprot id: A0A142KG99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1748:ASQ49 RS02255
gene id: 1748:ASQ49_RS02255
uniprot id: A0A806V7X8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1748:ASQ49 RS15985
gene id: 1748:ASQ49_RS15985
uniprot id: A0A142KKG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1748:ASQ49 RS09235
gene id: 1748:ASQ49_RS09235
uniprot id: A0A142KG39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1748:ASQ49 RS16500
gene id: 1748:ASQ49_RS16500
uniprot id: A0A806VFS9
names: Similarity
messages: Belongs to the DprA/Smf family.

1748:ASQ49 RS14995
gene id: 1748:ASQ49_RS14995
uniprot id: A0A806VDD9
names: Similarity
messages: Belongs to the peptidase C40 family.

1748:ASQ49 RS05180
gene id: 1748:ASQ49_RS05180
uniprot id: A0A142KI03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

1748:ASQ49 RS14965
gene id: 1748:ASQ49_RS14965
uniprot id: A0A806VDK1
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1748:ASQ49 RS11590
gene id: 1748:ASQ49_RS11590
uniprot id: A0A806VJ78
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1748:ASQ49 RS11575
gene id: 1748:ASQ49_RS11575
uniprot id: A0A142KDV3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS10885
gene id: 1748:ASQ49_RS10885
uniprot id: A0A806W003
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1748:ASQ49 RS12165
gene id: 1748:ASQ49_RS12165
uniprot id: A0A806W0D0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS01055
gene id: 1748:ASQ49_RS01055
uniprot id: A0A806VKX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1748:ASQ49 RS02285
gene id: 1748:ASQ49_RS02285
uniprot id: A0A142KIZ8
names: Similarity
messages: Belongs to the thioredoxin family.

1748:ASQ49 RS12300
gene id: 1748:ASQ49_RS12300
uniprot id: A0A806VFA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1748:ASQ49 RS05145
gene id: 1748:ASQ49_RS05145
uniprot id: A0A806VYA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1748:ASQ49 RS03965
gene id: 1748:ASQ49_RS03965
uniprot id: A0A806VXY5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS00355
gene id: 1748:ASQ49_RS00355
uniprot id: A0A142KJZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1748:ASQ49 RS09515
gene id: 1748:ASQ49_RS09515
uniprot id: A0A806VGA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1748:ASQ49 RS11260
gene id: 1748:ASQ49_RS11260
uniprot id: A0A142KF77
names: Similarity
messages: Belongs to the UPF0102 family.

1748:ASQ49 RS11000
gene id: 1748:ASQ49_RS11000
uniprot id: A0A142KFC1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS16040
gene id: 1748:ASQ49_RS16040
uniprot id: A0A806VL95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1748:ASQ49 RS09335
gene id: 1748:ASQ49_RS09335
uniprot id: A0A142KG20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1748:ASQ49 RS07450
gene id: 1748:ASQ49_RS07450
uniprot id: A0A806VAJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS02460
gene id: 1748:ASQ49_RS02460
uniprot id: A0A806V9U0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1748:ASQ49 RS02315
gene id: 1748:ASQ49_RS02315
uniprot id: A0A1P8U0Q6
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1748:ASQ49 RS14880
gene id: 1748:ASQ49_RS14880
uniprot id: A0A142KKY3
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1748:ASQ49 RS14600
gene id: 1748:ASQ49_RS14600
uniprot id: A0A142KL32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1748:ASQ49 RS15400
gene id: 1748:ASQ49_RS15400
uniprot id: A0A142KKP6
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1748:ASQ49 RS11105
gene id: 1748:ASQ49_RS11105
uniprot id: A0A806VC11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1748:ASQ49 RS11540
gene id: 1748:ASQ49_RS11540
uniprot id: A0A806VEY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1748:ASQ49 RS06070
gene id: 1748:ASQ49_RS06070
uniprot id: A0A142KHI4
names: Similarity
messages: Belongs to the YciI family.

1748:ASQ49 RS05230
gene id: 1748:ASQ49_RS05230
uniprot id: A0A1P8TZ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1748:ASQ49 RS08310
gene id: 1748:ASQ49_RS08310
uniprot id: A0A806VHV3
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS01220
gene id: 1748:ASQ49_RS01220
uniprot id: A0A806V7I3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1748:ASQ49 RS13545
gene id: 1748:ASQ49_RS13545
uniprot id: A0A806VCW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS10175
gene id: 1748:ASQ49_RS10175
uniprot id: A0A806W035
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS01095
gene id: 1748:ASQ49_RS01095
uniprot id: A0A806V7U1
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1748:ASQ49 RS06965
gene id: 1748:ASQ49_RS06965
uniprot id: A0A806V9Y6
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1748:ASQ49 RS09270
gene id: 1748:ASQ49_RS09270
uniprot id: A0A142KG32
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1748:ASQ49 RS08455
gene id: 1748:ASQ49_RS08455
uniprot id: A0A142KGG3
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS15275
gene id: 1748:ASQ49_RS15275
uniprot id: A0A142KKR7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1748:ASQ49 RS07310
gene id: 1748:ASQ49_RS07310
uniprot id: A0A806VA41
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS03880
gene id: 1748:ASQ49_RS03880
uniprot id: A0A142KIH2
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS09670
gene id: 1748:ASQ49_RS09670
uniprot id: A0A142KFW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1748:ASQ49 RS08855
gene id: 1748:ASQ49_RS08855
uniprot id: A0A806VB55
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1748:ASQ49 RS13850
gene id: 1748:ASQ49_RS13850
uniprot id: A0A806W197
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1748:ASQ49 RS03585
gene id: 1748:ASQ49_RS03585
uniprot id: A0A806VXV3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1748:ASQ49 RS03465
gene id: 1748:ASQ49_RS03465
uniprot id: A0A806VDY6
names: Similarity
messages: Belongs to the Vsr family.

1748:ASQ49 RS02200
gene id: 1748:ASQ49_RS02200
uniprot id: A0A806V7X0
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS12525
gene id: 1748:ASQ49_RS12525
uniprot id: A0A142KEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1748:ASQ49 RS08215
gene id: 1748:ASQ49_RS08215
uniprot id: A0A806VA73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS10210
gene id: 1748:ASQ49_RS10210
uniprot id: A0A806VBA0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1748:ASQ49 RS06030
gene id: 1748:ASQ49_RS06030
uniprot id: A0A142KHI8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1748:ASQ49 RS11065
gene id: 1748:ASQ49_RS11065
uniprot id: A0A806W022
names: Similarity
messages: Belongs to the TPP enzyme family.

1748:ASQ49 RS16100
gene id: 1748:ASQ49_RS16100
uniprot id: A0A806W1L2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1748:ASQ49 RS02520
gene id: 1748:ASQ49_RS02520
uniprot id: A0A806VXS6
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS00435
gene id: 1748:ASQ49_RS00435
uniprot id: A0A806V7F1
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS10650
gene id: 1748:ASQ49_RS10650
uniprot id: A0A142KFH8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1748:ASQ49 RS07570
gene id: 1748:ASQ49_RS07570
uniprot id: A0A806VAL5
names: Similarity
messages: Belongs to the GSP E family.

1748:ASQ49 RS12670
gene id: 1748:ASQ49_RS12670
uniprot id: A0A142KEC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1748:ASQ49 RS04980
gene id: 1748:ASQ49_RS04980
uniprot id: A0A806VH02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS03885
gene id: 1748:ASQ49_RS03885
uniprot id: A0A806V906
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1748:ASQ49 RS16260
gene id: 1748:ASQ49_RS16260
uniprot id: A0A806VFF2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS04205
gene id: 1748:ASQ49_RS04205
uniprot id: A0A806VY09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS10655
gene id: 1748:ASQ49_RS10655
uniprot id: A0A806VQ50
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1748:ASQ49 RS09160
gene id: 1748:ASQ49_RS09160
uniprot id: A0A142KG51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1748:ASQ49 RS15415
gene id: 1748:ASQ49_RS15415
uniprot id: A0A806VDK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1748:ASQ49 RS12590
gene id: 1748:ASQ49_RS12590
uniprot id: A0A806VJN1
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1748:ASQ49 RS07120
gene id: 1748:ASQ49_RS07120
uniprot id: A0A806VNJ0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS09970
gene id: 1748:ASQ49_RS09970
uniprot id: A0A142KFR2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1748:ASQ49 RS03395
gene id: 1748:ASQ49_RS03395
uniprot id: A0A806VM08
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1748:ASQ49 RS11670
gene id: 1748:ASQ49_RS11670
uniprot id: A0A806VGZ8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1748:ASQ49 RS03130
gene id: 1748:ASQ49_RS03130
uniprot id: A0A806VA30
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1748:ASQ49 RS08405
gene id: 1748:ASQ49_RS08405
uniprot id: A0A806VZI8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1748:ASQ49 RS05750
gene id: 1748:ASQ49_RS05750
uniprot id: A0A806VYR4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1748:ASQ49 RS14310
gene id: 1748:ASQ49_RS14310
uniprot id: A0A806VD06
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1748:ASQ49 RS12210
gene id: 1748:ASQ49_RS12210
uniprot id: A0A142KE48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1748:ASQ49 RS14750
gene id: 1748:ASQ49_RS14750
uniprot id: A0A142KL06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1748:ASQ49 RS15230
gene id: 1748:ASQ49_RS15230
uniprot id: A0A142KMH2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1748:ASQ49 RS02975
gene id: 1748:ASQ49_RS02975
uniprot id: A0A806VSX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS13695
gene id: 1748:ASQ49_RS13695
uniprot id: A0A806VCG7
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1748:ASQ49 RS08755
gene id: 1748:ASQ49_RS08755
uniprot id: A0A142KGB1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1748:ASQ49 RS09190
gene id: 1748:ASQ49_RS09190
uniprot id: A0A142KG45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1748:ASQ49 RS06360
gene id: 1748:ASQ49_RS06360
uniprot id: A0A806V9T8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1748:ASQ49 RS06400
gene id: 1748:ASQ49_RS06400
uniprot id: A0A806VBD9
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1748:ASQ49 RS15535
gene id: 1748:ASQ49_RS15535
uniprot id: A0A806W2B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS12450
gene id: 1748:ASQ49_RS12450
uniprot id: A0A806W0S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1748:ASQ49 RS15560
gene id: 1748:ASQ49_RS15560
uniprot id: A0A806W1G3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1748:ASQ49 RS08690
gene id: 1748:ASQ49_RS08690
uniprot id: A0A806VZN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS10760
gene id: 1748:ASQ49_RS10760
uniprot id: A0A806W090
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS12785
gene id: 1748:ASQ49_RS12785
uniprot id: A0A806VCI6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1748:ASQ49 RS14300
gene id: 1748:ASQ49_RS14300
uniprot id: A0A806VCR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1748:ASQ49 RS05695
gene id: 1748:ASQ49_RS05695
uniprot id: A0A806VN10
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1748:ASQ49 RS07015
gene id: 1748:ASQ49_RS07015
uniprot id: A0A806VFE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1748:ASQ49 RS02035
gene id: 1748:ASQ49_RS02035
uniprot id: A0A806V7V1
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS15665
gene id: 1748:ASQ49_RS15665
uniprot id: A0A142KKK0
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS07885
gene id: 1748:ASQ49_RS07885
uniprot id: A0A806VAQ7
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

1748:ASQ49 RS03240
gene id: 1748:ASQ49_RS03240
uniprot id: A0A142KIP6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1748:ASQ49 RS12690
gene id: 1748:ASQ49_RS12690
uniprot id: A0A142KED1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1748:ASQ49 RS11570
gene id: 1748:ASQ49_RS11570
uniprot id: A0A806W0H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1748:ASQ49 RS09320
gene id: 1748:ASQ49_RS09320
uniprot id: A0A806VPK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1748:ASQ49 RS08885
gene id: 1748:ASQ49_RS08885
uniprot id: A0A142KG89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1748:ASQ49 RS04020
gene id: 1748:ASQ49_RS04020
uniprot id: A0A806V8W0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1748:ASQ49 RS14910
gene id: 1748:ASQ49_RS14910
uniprot id: A0A806VDJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS13575
gene id: 1748:ASQ49_RS13575
uniprot id: A0A806VCE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1748:ASQ49 RS02140
gene id: 1748:ASQ49_RS02140
uniprot id: A0A806V7W4
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1748:ASQ49 RS04520
gene id: 1748:ASQ49_RS04520
uniprot id: A0A142KI73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS09385
gene id: 1748:ASQ49_RS09385
uniprot id: A0A806VAP2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1748:ASQ49 RS00915
gene id: 1748:ASQ49_RS00915
uniprot id: A0A806V942
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1748:ASQ49 RS14700
gene id: 1748:ASQ49_RS14700
uniprot id: A0A806VCY4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1748:ASQ49 RS13645
gene id: 1748:ASQ49_RS13645
uniprot id: A0A142KF06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1748:ASQ49 RS06905
gene id: 1748:ASQ49_RS06905
uniprot id: A0A806VIZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS04145
gene id: 1748:ASQ49_RS04145
uniprot id: A0A806VY01
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1748:ASQ49 RS04935
gene id: 1748:ASQ49_RS04935
uniprot id: A0A142KI38
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1748:ASQ49 RS00470
gene id: 1748:ASQ49_RS00470
uniprot id: A0A806V776
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1748:ASQ49 RS05000
gene id: 1748:ASQ49_RS05000
uniprot id: A0A142KI28
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS07085
gene id: 1748:ASQ49_RS07085
uniprot id: A0A806VFF0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1748:ASQ49 RS02540
gene id: 1748:ASQ49_RS02540
uniprot id: A0A806VE90
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1748:ASQ49 RS13810
gene id: 1748:ASQ49_RS13810
uniprot id: A0A806VCJ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1748:ASQ49 RS07840
gene id: 1748:ASQ49_RS07840
uniprot id: A0A806VAD8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1748:ASQ49 RS00830
gene id: 1748:ASQ49_RS00830
uniprot id: A0A142KJR1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1748:ASQ49 RS13205
gene id: 1748:ASQ49_RS13205
uniprot id: A0A806VED4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

1748:ASQ49 RS14205
gene id: 1748:ASQ49_RS14205
uniprot id: A0A806VD68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS09060
gene id: 1748:ASQ49_RS09060
uniprot id: A0A806VAV1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1748:ASQ49 RS16455
gene id: 1748:ASQ49_RS16455
uniprot id: A0A806W204
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1748:ASQ49 RS08090
gene id: 1748:ASQ49_RS08090
uniprot id: A0A806VZF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1748:ASQ49 RS05610
gene id: 1748:ASQ49_RS05610
uniprot id: A0A806VYQ1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1748:ASQ49 RS12730
gene id: 1748:ASQ49_RS12730
uniprot id: A0A806W0W2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS06015
gene id: 1748:ASQ49_RS06015
uniprot id: A0A806VB91
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1748:ASQ49 RS16005
gene id: 1748:ASQ49_RS16005
uniprot id: A0A142KKF9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS05445
gene id: 1748:ASQ49_RS05445
uniprot id: A0A806V9G5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS04040
gene id: 1748:ASQ49_RS04040
uniprot id: A0A142KIE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1748:ASQ49 RS14165
gene id: 1748:ASQ49_RS14165
uniprot id: A0A142KDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1748:ASQ49 RS11565
gene id: 1748:ASQ49_RS11565
uniprot id: A0A142KDV1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1748:ASQ49 RS11075
gene id: 1748:ASQ49_RS11075
uniprot id: A0A806VJ02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1748:ASQ49 RS13375
gene id: 1748:ASQ49_RS13375
uniprot id: A0A142KEQ3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1748:ASQ49 RS14520
gene id: 1748:ASQ49_RS14520
uniprot id: A0A142KL47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1748:ASQ49 RS13455
gene id: 1748:ASQ49_RS13455
uniprot id: A0A806VCK8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1748:ASQ49 RS09860
gene id: 1748:ASQ49_RS09860
uniprot id: A0A806VAV6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1748:ASQ49 RS08895
gene id: 1748:ASQ49_RS08895
uniprot id: A0A806VG33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1748:ASQ49 RS01135
gene id: 1748:ASQ49_RS01135
uniprot id: A0A806V7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS10870
gene id: 1748:ASQ49_RS10870
uniprot id: A0A806VEW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1748:ASQ49 RS00450
gene id: 1748:ASQ49_RS00450
uniprot id: A0A806VFC1
names: Similarity
messages: Belongs to the CobH/CbiC family.

1748:ASQ49 RS12225
gene id: 1748:ASQ49_RS12225
uniprot id: A0A3Q9CN33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1748:ASQ49 RS09290
gene id: 1748:ASQ49_RS09290
uniprot id: A0A142KG28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS07205
gene id: 1748:ASQ49_RS07205
uniprot id: A0A806VA23
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS00750
gene id: 1748:ASQ49_RS00750
uniprot id: A0A806V917
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS13670
gene id: 1748:ASQ49_RS13670
uniprot id: A0A806W0V1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1748:ASQ49 RS05365
gene id: 1748:ASQ49_RS05365
uniprot id: A0A142KHV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1748:ASQ49 RS00945
gene id: 1748:ASQ49_RS00945
uniprot id: A0A806VKV6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1748:ASQ49 RS15950
gene id: 1748:ASQ49_RS15950
uniprot id: A0A806VE56
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS04090
gene id: 1748:ASQ49_RS04090
uniprot id: A0A806VGQ1
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS05335
gene id: 1748:ASQ49_RS05335
uniprot id: A0A806VMV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS12990
gene id: 1748:ASQ49_RS12990
uniprot id: A0A806VJV0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1748:ASQ49 RS03220
gene id: 1748:ASQ49_RS03220
uniprot id: A0A806VEK2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1748:ASQ49 RS11265
gene id: 1748:ASQ49_RS11265
uniprot id: A0A142KF76
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1748:ASQ49 RS02965
gene id: 1748:ASQ49_RS02965
uniprot id: A0A806VXN7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1748:ASQ49 RS01605
gene id: 1748:ASQ49_RS01605
uniprot id: A0A806VFT3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1748:ASQ49 RS09585
gene id: 1748:ASQ49_RS09585
uniprot id: A0A142KFX5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1748:ASQ49 RS08730
gene id: 1748:ASQ49_RS08730
uniprot id: A0A806VAQ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS00950
gene id: 1748:ASQ49_RS00950
uniprot id: A0A142KJP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS08385
gene id: 1748:ASQ49_RS08385
uniprot id: A0A142KGH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1748:ASQ49 RS13925
gene id: 1748:ASQ49_RS13925
uniprot id: A0A806VD18
names: Similarity
messages: Belongs to the group II decarboxylase family.

1748:ASQ49 RS10460
gene id: 1748:ASQ49_RS10460
uniprot id: A0A806VB32
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1748:ASQ49 RS06690
gene id: 1748:ASQ49_RS06690
uniprot id: A0A806VNE0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1748:ASQ49 RS17180
gene id: 1748:ASQ49_RS17180
uniprot id: A0A806VM83
names: Similarity
messages: Belongs to the MEMO1 family.

1748:ASQ49 RS03230
gene id: 1748:ASQ49_RS03230
uniprot id: A0A806VXR3
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1748:ASQ49 RS13285
gene id: 1748:ASQ49_RS13285
uniprot id: A0A806VR98
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1748:ASQ49 RS08740
gene id: 1748:ASQ49_RS08740
uniprot id: A0A806VB37
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS14055
gene id: 1748:ASQ49_RS14055
uniprot id: A0A806W0Z5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1748:ASQ49 RS06680
gene id: 1748:ASQ49_RS06680
uniprot id: A0A806VYS0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1748:ASQ49 RS10620
gene id: 1748:ASQ49_RS10620
uniprot id: A0A806VD82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

1748:ASQ49 RS10880
gene id: 1748:ASQ49_RS10880
uniprot id: A0A806VBN1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1748:ASQ49 RS05670
gene id: 1748:ASQ49_RS05670
uniprot id: A0A806V9T4
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1748:ASQ49 RS15075
gene id: 1748:ASQ49_RS15075
uniprot id: A0A806VDL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1748:ASQ49 RS15370
gene id: 1748:ASQ49_RS15370
uniprot id: A0A806VDW3
names: Similarity
messages: Belongs to the LOG family.

1748:ASQ49 RS04630
gene id: 1748:ASQ49_RS04630
uniprot id: A0A806VY51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1748:ASQ49 RS02925
gene id: 1748:ASQ49_RS02925
uniprot id: A0A806VDU0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1748:ASQ49 RS03740
gene id: 1748:ASQ49_RS03740
uniprot id: A0A806W1U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1748:ASQ49 RS07490
gene id: 1748:ASQ49_RS07490
uniprot id: A0A806VA68
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1748:ASQ49 RS07050
gene id: 1748:ASQ49_RS07050
uniprot id: A0A806VES5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS04990
gene id: 1748:ASQ49_RS04990
uniprot id: A0A806VEM6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1748:ASQ49 RS10615
gene id: 1748:ASQ49_RS10615
uniprot id: A0A142KFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS11505
gene id: 1748:ASQ49_RS11505
uniprot id: A0A806W065
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1748:ASQ49 RS06220
gene id: 1748:ASQ49_RS06220
uniprot id: A0A806W1X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1748:ASQ49 RS09185
gene id: 1748:ASQ49_RS09185
uniprot id: A0A806VCK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1748:ASQ49 RS02190
gene id: 1748:ASQ49_RS02190
uniprot id: A0A806VDG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1748:ASQ49 RS13450
gene id: 1748:ASQ49_RS13450
uniprot id: A0A806VHF8
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1748:ASQ49 RS13075
gene id: 1748:ASQ49_RS13075
uniprot id: A0A806W2A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS00555
gene id: 1748:ASQ49_RS00555
uniprot id: A0A806VLI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1748:ASQ49 RS10530
gene id: 1748:ASQ49_RS10530
uniprot id: A0A1P8TX23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1748:ASQ49 RS03955
gene id: 1748:ASQ49_RS03955
uniprot id: A0A806V8V1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1748:ASQ49 RS08880
gene id: 1748:ASQ49_RS08880
uniprot id: A0A142KG90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1748:ASQ49 RS10895
gene id: 1748:ASQ49_RS10895
uniprot id: A0A806VGF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1748:ASQ49 RS01360
gene id: 1748:ASQ49_RS01360
uniprot id: A0A806V7T9
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS07905
gene id: 1748:ASQ49_RS07905
uniprot id: A0A806VNX4
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1748:ASQ49 RS03285
gene id: 1748:ASQ49_RS03285
uniprot id: A0A806VLZ3
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS03160
gene id: 1748:ASQ49_RS03160
uniprot id: A0A806VLX7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1748:ASQ49 RS14770
gene id: 1748:ASQ49_RS14770
uniprot id: A0A806VDA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1748:ASQ49 RS10805
gene id: 1748:ASQ49_RS10805
uniprot id: A0A142KFF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1748:ASQ49 RS01750
gene id: 1748:ASQ49_RS01750
uniprot id: A0A806VEH5
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

1748:ASQ49 RS06080
gene id: 1748:ASQ49_RS06080
uniprot id: A0A806VA02
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS11515
gene id: 1748:ASQ49_RS11515
uniprot id: A0A1P8TWJ0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1748:ASQ49 RS11465
gene id: 1748:ASQ49_RS11465
uniprot id: A0A806VBH6
names: Similarity
messages: Belongs to the TlyA family.

1748:ASQ49 RS08955
gene id: 1748:ASQ49_RS08955
uniprot id: A0A806VPE9
names: Similarity
messages: Belongs to the peptidase M13 family.

1748:ASQ49 RS16000
gene id: 1748:ASQ49_RS16000
uniprot id: A0A806VDV0
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS07065
gene id: 1748:ASQ49_RS07065
uniprot id: A0A806VYV4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1748:ASQ49 RS11970
gene id: 1748:ASQ49_RS11970
uniprot id: A0A806W0M0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1748:ASQ49 RS08095
gene id: 1748:ASQ49_RS08095
uniprot id: A0A806VAH3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1748:ASQ49 RS09555
gene id: 1748:ASQ49_RS09555
uniprot id: A0A142KFY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1748:ASQ49 RS13730
gene id: 1748:ASQ49_RS13730
uniprot id: A0A142KF20
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1748:ASQ49 RS11925
gene id: 1748:ASQ49_RS11925
uniprot id: A0A806VQP0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1748:ASQ49 RS00480
gene id: 1748:ASQ49_RS00480
uniprot id: A0A806V7K5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1748:ASQ49 RS14740
gene id: 1748:ASQ49_RS14740
uniprot id: A0A806VDG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1748:ASQ49 RS09445
gene id: 1748:ASQ49_RS09445
uniprot id: A0A142KG00
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1748:ASQ49 RS09225
gene id: 1748:ASQ49_RS09225
uniprot id: A0A806VI77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS08425
gene id: 1748:ASQ49_RS08425
uniprot id: A0A806VHW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Belongs to the SAICAR synthetase family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1748:ASQ49 RS13790
gene id: 1748:ASQ49_RS13790
uniprot id: A0A806VCZ8
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS01620
gene id: 1748:ASQ49_RS01620
uniprot id: A0A142KJC4
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS01830
gene id: 1748:ASQ49_RS01830
uniprot id: A0A806V836
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS08920
gene id: 1748:ASQ49_RS08920
uniprot id: A0A806VB62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1748:ASQ49 RS15485
gene id: 1748:ASQ49_RS15485
uniprot id: A0A142KKN1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1748:ASQ49 RS09480
gene id: 1748:ASQ49_RS09480
uniprot id: A0A142KFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1748:ASQ49 RS14390
gene id: 1748:ASQ49_RS14390
uniprot id: A0A806VDF2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1748:ASQ49 RS12575
gene id: 1748:ASQ49_RS12575
uniprot id: A0A142KEB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1748:ASQ49 RS16195
gene id: 1748:ASQ49_RS16195
uniprot id: A0A806W1L5
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1748:ASQ49 RS00270
gene id: 1748:ASQ49_RS00270
uniprot id: A0A806VWP4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1748:ASQ49 RS11460
gene id: 1748:ASQ49_RS11460
uniprot id: A0A806VJ59
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS12050
gene id: 1748:ASQ49_RS12050
uniprot id: A0A806VTG0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1748:ASQ49 RS15015
gene id: 1748:ASQ49_RS15015
uniprot id: A0A142KKV8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1748:ASQ49 RS12180
gene id: 1748:ASQ49_RS12180
uniprot id: A0A142KE43
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1748:ASQ49 RS05570
gene id: 1748:ASQ49_RS05570
uniprot id: A0A806VMZ1
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1748:ASQ49 RS14510
gene id: 1748:ASQ49_RS14510
uniprot id: A0A142KL49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1748:ASQ49 RS11825
gene id: 1748:ASQ49_RS11825
uniprot id: A0A142KDY9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1748:ASQ49 RS03200
gene id: 1748:ASQ49_RS03200
uniprot id: A0A806VA39
names: Similarity
messages: Belongs to the UxaA family.

1748:ASQ49 RS15980
gene id: 1748:ASQ49_RS15980
uniprot id: A0A806VL85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1748:ASQ49 RS14595
gene id: 1748:ASQ49_RS14595
uniprot id: A0A142KL33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1748:ASQ49 RS11055
gene id: 1748:ASQ49_RS11055
uniprot id: A0A806W0B8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1748:ASQ49 RS10340
gene id: 1748:ASQ49_RS10340
uniprot id: A0A142KFL9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1748:ASQ49 RS12395
gene id: 1748:ASQ49_RS12395
uniprot id: A0A806VCJ6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1748:ASQ49 RS11385
gene id: 1748:ASQ49_RS11385
uniprot id: A0A806VJ50
names: Similarity
messages: Belongs to the citrate synthase family.

1748:ASQ49 RS12205
gene id: 1748:ASQ49_RS12205
uniprot id: A0A142KLE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1748:ASQ49 RS01240
gene id: 1748:ASQ49_RS01240
uniprot id: A0A806V7S2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1748:ASQ49 RS12665
gene id: 1748:ASQ49_RS12665
uniprot id: A0A806VC88
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1748:ASQ49 RS01530
gene id: 1748:ASQ49_RS01530
uniprot id: A0A806V7W1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1748:ASQ49 RS09520
gene id: 1748:ASQ49_RS09520
uniprot id: A0A142KFY7
names: Similarity
messages: Belongs to the peptidase C1 family.

1748:ASQ49 RS02030
gene id: 1748:ASQ49_RS02030
uniprot id: A0A806VDD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1748:ASQ49 RS11955
gene id: 1748:ASQ49_RS11955
uniprot id: A0A142KE06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS13520
gene id: 1748:ASQ49_RS13520
uniprot id: A0A142KES5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1748:ASQ49 RS11605
gene id: 1748:ASQ49_RS11605
uniprot id: A0A806VBT9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1748:ASQ49 RS09640
gene id: 1748:ASQ49_RS09640
uniprot id: A0A142KFW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1748:ASQ49 RS14660
gene id: 1748:ASQ49_RS14660
uniprot id: A0A142KL21
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1748:ASQ49 RS05560
gene id: 1748:ASQ49_RS05560
uniprot id: A0A806V9H9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1748:ASQ49 RS00465
gene id: 1748:ASQ49_RS00465
uniprot id: A0A806VCK3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1748:ASQ49 RS10395
gene id: 1748:ASQ49_RS10395
uniprot id: A0A806VGK6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1748:ASQ49 RS08345
gene id: 1748:ASQ49_RS08345
uniprot id: A0A806VAL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1748:ASQ49 RS04215
gene id: 1748:ASQ49_RS04215
uniprot id: A0A806VGR8
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1748:ASQ49 RS13245
gene id: 1748:ASQ49_RS13245
uniprot id: A0A142KLG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1748:ASQ49 RS16085
gene id: 1748:ASQ49_RS16085
uniprot id: A0A142KMF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1748:ASQ49 RS16255
gene id: 1748:ASQ49_RS16255
uniprot id: A0A806W2C1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1748:ASQ49 RS05490
gene id: 1748:ASQ49_RS05490
uniprot id: A0A142KHT1
names: Similarity
messages: Belongs to the peptidase C1 family.

1748:ASQ49 RS16330
gene id: 1748:ASQ49_RS16330
uniprot id: A0A806VEA3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1748:ASQ49 RS04325
gene id: 1748:ASQ49_RS04325
uniprot id: A0A806VY22
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS12440
gene id: 1748:ASQ49_RS12440
uniprot id: A0A142KE85
names: Similarity
messages: Belongs to the TrpC family.

1748:ASQ49 RS05975
gene id: 1748:ASQ49_RS05975
uniprot id: A0A806VYU2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1748:ASQ49 RS09260
gene id: 1748:ASQ49_RS09260
uniprot id: A0A142KG34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1748:ASQ49 RS12045
gene id: 1748:ASQ49_RS12045
uniprot id: A0A806VJD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1748:ASQ49 RS13610
gene id: 1748:ASQ49_RS13610
uniprot id: A0A806VML2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1748:ASQ49 RS01025
gene id: 1748:ASQ49_RS01025
uniprot id: A0A806V959
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1748:ASQ49 RS06225
gene id: 1748:ASQ49_RS06225
uniprot id: A0A806VF40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS14725
gene id: 1748:ASQ49_RS14725
uniprot id: A0A806VF21
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1748:ASQ49 RS10525
gene id: 1748:ASQ49_RS10525
uniprot id: A0A142KLL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1748:ASQ49 RS06005
gene id: 1748:ASQ49_RS06005
uniprot id: A0A806VF18
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1748:ASQ49 RS00370
gene id: 1748:ASQ49_RS00370
uniprot id: A0A142KJZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1748:ASQ49 RS05505
gene id: 1748:ASQ49_RS05505
uniprot id: A0A806VYN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1748:ASQ49 RS09525
gene id: 1748:ASQ49_RS09525
uniprot id: A0A806VCR4
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1748:ASQ49 RS16135
gene id: 1748:ASQ49_RS16135
uniprot id: A0A806VE83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1748:ASQ49 RS11195
gene id: 1748:ASQ49_RS11195
uniprot id: A0A806VBE0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1748:ASQ49 RS08250
gene id: 1748:ASQ49_RS08250
uniprot id: A0A142KGK0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1748:ASQ49 RS16830
gene id: 1748:ASQ49_RS16830
uniprot id: A0A1P8TZE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1748:ASQ49 RS13210
gene id: 1748:ASQ49_RS13210
uniprot id: A0A806VCX8
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS12455
gene id: 1748:ASQ49_RS12455
uniprot id: A0A142KE88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1748:ASQ49 RS00290
gene id: 1748:ASQ49_RS00290
uniprot id: A0A806VFU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1748:ASQ49 RS07145
gene id: 1748:ASQ49_RS07145
uniprot id: A0A806VA11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS01745
gene id: 1748:ASQ49_RS01745
uniprot id: A0A142KJA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1748:ASQ49 RS10855
gene id: 1748:ASQ49_RS10855
uniprot id: A0A806VBI2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1748:ASQ49 RS09245
gene id: 1748:ASQ49_RS09245
uniprot id: A0A142KG37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1748:ASQ49 RS11600
gene id: 1748:ASQ49_RS11600
uniprot id: A0A806VGZ3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1748:ASQ49 RS00725
gene id: 1748:ASQ49_RS00725
uniprot id: A0A806VKR7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1748:ASQ49 RS06310
gene id: 1748:ASQ49_RS06310
uniprot id: A0A806VYN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS05235
gene id: 1748:ASQ49_RS05235
uniprot id: A0A806VAY7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1748:ASQ49 RS07860
gene id: 1748:ASQ49_RS07860
uniprot id: A0A806VHP7
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1748:ASQ49 RS04230
gene id: 1748:ASQ49_RS04230
uniprot id: A0A806V8S5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1748:ASQ49 RS10635
gene id: 1748:ASQ49_RS10635
uniprot id: A0A806W078
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1748:ASQ49 RS15085
gene id: 1748:ASQ49_RS15085
uniprot id: A0A806VJH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1748:ASQ49 RS08860
gene id: 1748:ASQ49_RS08860
uniprot id: A0A142KG94
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1748:ASQ49 RS14540
gene id: 1748:ASQ49_RS14540
uniprot id: A0A142KL44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1748:ASQ49 RS11450
gene id: 1748:ASQ49_RS11450
uniprot id: A0A142KDT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1748:ASQ49 RS11715
gene id: 1748:ASQ49_RS11715
uniprot id: A0A142KDX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1748:ASQ49 RS13675
gene id: 1748:ASQ49_RS13675
uniprot id: A0A142KLI1
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1748:ASQ49 RS14570
gene id: 1748:ASQ49_RS14570
uniprot id: A0A806VDC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1748:ASQ49 RS10475
gene id: 1748:ASQ49_RS10475
uniprot id: A0A806VD64
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1748:ASQ49 RS01125
gene id: 1748:ASQ49_RS01125
uniprot id: A0A142KJL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1748:ASQ49 RS10960
gene id: 1748:ASQ49_RS10960
uniprot id: A0A806VIY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1748:ASQ49 RS14940
gene id: 1748:ASQ49_RS14940
uniprot id: A0A806VHX5
names: Function
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1748:ASQ49 RS05520
gene id: 1748:ASQ49_RS05520
uniprot id: A0A142KM16
names: Similarity
messages: Belongs to the UPF0237 family.

1748:ASQ49 RS08270
gene id: 1748:ASQ49_RS08270
uniprot id: A0A806VFV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1748:ASQ49 RS15355
gene id: 1748:ASQ49_RS15355
uniprot id: A0A142KKQ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS13405
gene id: 1748:ASQ49_RS13405
uniprot id: A0A142KEQ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1748:ASQ49 RS04300
gene id: 1748:ASQ49_RS04300
uniprot id: A0A806VAL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1748:ASQ49 RS16200
gene id: 1748:ASQ49_RS16200
uniprot id: A0A806VSL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

1748:ASQ49 RS08240
gene id: 1748:ASQ49_RS08240
uniprot id: A0A806VZH2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1748:ASQ49 RS16090
gene id: 1748:ASQ49_RS16090
uniprot id: A0A142KKE6
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1748:ASQ49 RS14530
gene id: 1748:ASQ49_RS14530
uniprot id: A0A142KL46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1748:ASQ49 RS12705
gene id: 1748:ASQ49_RS12705
uniprot id: A0A142KED4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1748:ASQ49 RS04220
gene id: 1748:ASQ49_RS04220
uniprot id: A0A806V8I3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1748:ASQ49 RS08500
gene id: 1748:ASQ49_RS08500
uniprot id: A0A806VC86
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1748:ASQ49 RS09275
gene id: 1748:ASQ49_RS09275
uniprot id: A0A806VI86
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1748:ASQ49 RS07350
gene id: 1748:ASQ49_RS07350
uniprot id: A0A142KGY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1748:ASQ49 RS04365
gene id: 1748:ASQ49_RS04365
uniprot id: A0A806V979
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS14195
gene id: 1748:ASQ49_RS14195
uniprot id: A0A806VDC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1748:ASQ49 RS11045
gene id: 1748:ASQ49_RS11045
uniprot id: A0A142KFB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1748:ASQ49 RS09780
gene id: 1748:ASQ49_RS09780
uniprot id: A0A142KFU3
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS14050
gene id: 1748:ASQ49_RS14050
uniprot id: A0A806VD38
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS02115
gene id: 1748:ASQ49_RS02115
uniprot id: A0A806VXC4
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS06765
gene id: 1748:ASQ49_RS06765
uniprot id: A0A806VEJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1748:ASQ49 RS00310
gene id: 1748:ASQ49_RS00310
uniprot id: A0A142KK62
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS09655
gene id: 1748:ASQ49_RS09655
uniprot id: A0A806VB63
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1748:ASQ49 RS01280
gene id: 1748:ASQ49_RS01280
uniprot id: A0A806V7W2
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1748:ASQ49 RS14625
gene id: 1748:ASQ49_RS14625
uniprot id: A0A806W161
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1748:ASQ49 RS10160
gene id: 1748:ASQ49_RS10160
uniprot id: A0A806VD15
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1748:ASQ49 RS14785
gene id: 1748:ASQ49_RS14785
uniprot id: A0A142KL00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1748:ASQ49 RS10220
gene id: 1748:ASQ49_RS10220
uniprot id: A0A806VEG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1748:ASQ49 RS07425
gene id: 1748:ASQ49_RS07425
uniprot id: A0A806V9W3
names: Similarity
messages: Belongs to the UPF0246 family.

1748:ASQ49 RS09315
gene id: 1748:ASQ49_RS09315
uniprot id: A0A142KG23
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1748:ASQ49 RS02455
gene id: 1748:ASQ49_RS02455
uniprot id: A0A806V814
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1748:ASQ49 RS01080
gene id: 1748:ASQ49_RS01080
uniprot id: A0A806V7G5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS09120
gene id: 1748:ASQ49_RS09120
uniprot id: A0A806VAV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1748:ASQ49 RS08790
gene id: 1748:ASQ49_RS08790
uniprot id: A0A1P8TXU5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS13655
gene id: 1748:ASQ49_RS13655
uniprot id: A0A142KF08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1748:ASQ49 RS14590
gene id: 1748:ASQ49_RS14590
uniprot id: A0A142KL34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1748:ASQ49 RS03295
gene id: 1748:ASQ49_RS03295
uniprot id: A0A806VGE8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1748:ASQ49 RS00325
gene id: 1748:ASQ49_RS00325
uniprot id: A0A142KK59
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1748:ASQ49 RS07260
gene id: 1748:ASQ49_RS07260
uniprot id: A0A806VA31
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS16105
gene id: 1748:ASQ49_RS16105
uniprot id: A0A142KKE3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1748:ASQ49 RS15125
gene id: 1748:ASQ49_RS15125
uniprot id: A0A806W1Q8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1748:ASQ49 RS11985
gene id: 1748:ASQ49_RS11985
uniprot id: A0A142KE11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1748:ASQ49 RS08815
gene id: 1748:ASQ49_RS08815
uniprot id: A0A806VZF1
names: Similarity
messages: Belongs to the barstar family.

1748:ASQ49 RS02495
gene id: 1748:ASQ49_RS02495
uniprot id: A0A806V7W6
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS10975
gene id: 1748:ASQ49_RS10975
uniprot id: A0A806VBJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1748:ASQ49 RS13295
gene id: 1748:ASQ49_RS13295
uniprot id: A0A806VCA9
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS15315
gene id: 1748:ASQ49_RS15315
uniprot id: A0A806VFB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1748:ASQ49 RS09165
gene id: 1748:ASQ49_RS09165
uniprot id: A0A142KG50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1748:ASQ49 RS10430
gene id: 1748:ASQ49_RS10430
uniprot id: A0A806W063
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS13105
gene id: 1748:ASQ49_RS13105
uniprot id: A0A806W107
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1748:ASQ49 RS11480
gene id: 1748:ASQ49_RS11480
uniprot id: A0A142KDT9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1748:ASQ49 RS00585
gene id: 1748:ASQ49_RS00585
uniprot id: A0A806VCM3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1748:ASQ49 RS07650
gene id: 1748:ASQ49_RS07650
uniprot id: A0A806VNS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1748:ASQ49 RS13485
gene id: 1748:ASQ49_RS13485
uniprot id: A0A806W0S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1748:ASQ49 RS12515
gene id: 1748:ASQ49_RS12515
uniprot id: A0A806VF17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1748:ASQ49 RS11745
gene id: 1748:ASQ49_RS11745
uniprot id: A0A142KDX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1748:ASQ49 RS09345
gene id: 1748:ASQ49_RS09345
uniprot id: A0A142KG18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1748:ASQ49 RS09000
gene id: 1748:ASQ49_RS09000
uniprot id: A0A806VB71
names: Similarity
messages: Belongs to the UPF0234 family.

1748:ASQ49 RS15050
gene id: 1748:ASQ49_RS15050
uniprot id: A0A142KKV1
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1748:ASQ49 RS14280
gene id: 1748:ASQ49_RS14280
uniprot id: A0A806VD79
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1748:ASQ49 RS14815
gene id: 1748:ASQ49_RS14815
uniprot id: A0A806VKN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1748:ASQ49 RS16080
gene id: 1748:ASQ49_RS16080
uniprot id: A0A806VE73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1748:ASQ49 RS05065
gene id: 1748:ASQ49_RS05065
uniprot id: A0A142KI16
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1748:ASQ49 RS00665
gene id: 1748:ASQ49_RS00665
uniprot id: A0A806V7I6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1748:ASQ49 RS09565
gene id: 1748:ASQ49_RS09565
uniprot id: A0A806VAR5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS05060
gene id: 1748:ASQ49_RS05060
uniprot id: A0A806V9I9
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS13685
gene id: 1748:ASQ49_RS13685
uniprot id: A0A142KF13
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1748:ASQ49 RS14870
gene id: 1748:ASQ49_RS14870
uniprot id: A0A806VKP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS15510
gene id: 1748:ASQ49_RS15510
uniprot id: A0A806VGQ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1748:ASQ49 RS07800
gene id: 1748:ASQ49_RS07800
uniprot id: A0A806VA20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS06045
gene id: 1748:ASQ49_RS06045
uniprot id: A0A806VH97
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1748:ASQ49 RS09575
gene id: 1748:ASQ49_RS09575
uniprot id: A0A806VB20
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1748:ASQ49 RS03535
gene id: 1748:ASQ49_RS03535
uniprot id: A0A142KIN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1748:ASQ49 RS00960
gene id: 1748:ASQ49_RS00960
uniprot id: A0A142KJN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS12000
gene id: 1748:ASQ49_RS12000
uniprot id: A0A806VH24
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1748:ASQ49 RS02050
gene id: 1748:ASQ49_RS02050
uniprot id: A0A806VXK3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1748:ASQ49 RS11220
gene id: 1748:ASQ49_RS11220
uniprot id: A0A142KLJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1748:ASQ49 RS07420
gene id: 1748:ASQ49_RS07420
uniprot id: A0A142KLW1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1748:ASQ49 RS10085
gene id: 1748:ASQ49_RS10085
uniprot id: A0A806W027
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1748:ASQ49 RS14795
gene id: 1748:ASQ49_RS14795
uniprot id: A0A806VDH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1748:ASQ49 RS09355
gene id: 1748:ASQ49_RS09355
uniprot id: A0A142KG16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1748:ASQ49 RS01445
gene id: 1748:ASQ49_RS01445
uniprot id: A0A806VDU5
names: Subcellular Location Annotation
messages: Membrane

1748:ASQ49 RS06910
gene id: 1748:ASQ49_RS06910
uniprot id: A0A806VBJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS11050
gene id: 1748:ASQ49_RS11050
uniprot id: A0A806VC02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1748:ASQ49 RS14035
gene id: 1748:ASQ49_RS14035
uniprot id: A0A142KDS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1748:ASQ49 RS14090
gene id: 1748:ASQ49_RS14090
uniprot id: A0A806VER9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1748:ASQ49 RS06705
gene id: 1748:ASQ49_RS06705
uniprot id: A0A806V9L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1748:ASQ49 RS01845
gene id: 1748:ASQ49_RS01845
uniprot id: A0A806VX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1748:ASQ49 RS16550
gene id: 1748:ASQ49_RS16550
uniprot id: A0A806VFT6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.