1736674:APS56 RS15585
gene id: 1736674:APS56_RS15585
uniprot id: A0A0P0D6B6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS01550
gene id: 1736674:APS56_RS01550
uniprot id: A0A0P0CDD1
names: Similarity
messages: Belongs to the LOG family.

1736674:APS56 RS03755
gene id: 1736674:APS56_RS03755
uniprot id: A0A0P0CIX3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1736674:APS56 RS08440
gene id: 1736674:APS56_RS08440
uniprot id: A0A0P0CG56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1736674:APS56 RS04605
gene id: 1736674:APS56_RS04605
uniprot id: A0A0P0D9J3
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1736674:APS56 RS13165
gene id: 1736674:APS56_RS13165
uniprot id: A0A0N7HYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

1736674:APS56 RS13945
gene id: 1736674:APS56_RS13945
uniprot id: A0A0P0CIY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1736674:APS56 RS04955
gene id: 1736674:APS56_RS04955
uniprot id: A0A0P0D3I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS06675
gene id: 1736674:APS56_RS06675
uniprot id: A0A0P0D7X7
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1736674:APS56 RS02960
gene id: 1736674:APS56_RS02960
uniprot id: A0A0P0D0E3
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS07490
gene id: 1736674:APS56_RS07490
uniprot id: A0A0P0DAD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1736674:APS56 RS04020
gene id: 1736674:APS56_RS04020
uniprot id: A0A0P0D901
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1736674:APS56 RS08555
gene id: 1736674:APS56_RS08555
uniprot id: A0A0P0DB76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1736674:APS56 RS13915
gene id: 1736674:APS56_RS13915
uniprot id: A0A0N7HYT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS06655
gene id: 1736674:APS56_RS06655
uniprot id: A0A0P0CPP6
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS15170
gene id: 1736674:APS56_RS15170
uniprot id: A0A0P0CJJ5
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS13020
gene id: 1736674:APS56_RS13020
uniprot id: A0A0P0CT27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS03110
gene id: 1736674:APS56_RS03110
uniprot id: A0A0P0D2U0
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS14165
gene id: 1736674:APS56_RS14165
uniprot id: A0A0P0DBB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1736674:APS56 RS04885
gene id: 1736674:APS56_RS04885
uniprot id: A0A0P0CJH0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1736674:APS56 RS10940
gene id: 1736674:APS56_RS10940
uniprot id: A0A0P0CRZ3
names: Similarity
messages: Belongs to the peptidase S41A family.

1736674:APS56 RS12585
gene id: 1736674:APS56_RS12585
uniprot id: A0A0P0CZ67
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS04130
gene id: 1736674:APS56_RS04130
uniprot id: A0A0P0CNH7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1736674:APS56 RS10010
gene id: 1736674:APS56_RS10010
uniprot id: A0A0P0D5P2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1736674:APS56 RS06410
gene id: 1736674:APS56_RS06410
uniprot id: A0A0P0CK40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1736674:APS56 RS02425
gene id: 1736674:APS56_RS02425
uniprot id: A0A0P0D096
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1736674:APS56 RS10930
gene id: 1736674:APS56_RS10930
uniprot id: A0A0P0CHF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1736674:APS56 RS13745
gene id: 1736674:APS56_RS13745
uniprot id: A0A0P0CNX1
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

1736674:APS56 RS16625
gene id: 1736674:APS56_RS16625
uniprot id: A0A0P0D6V1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1736674:APS56 RS02350
gene id: 1736674:APS56_RS02350
uniprot id: A0A0P0CMR8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1736674:APS56 RS08175
gene id: 1736674:APS56_RS08175
uniprot id: A0A0N7HYF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1736674:APS56 RS01105
gene id: 1736674:APS56_RS01105
uniprot id: A0A0P0D7S2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1736674:APS56 RS06825
gene id: 1736674:APS56_RS06825
uniprot id: A0A0P0CFE1
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS01465
gene id: 1736674:APS56_RS01465
uniprot id: A0A0P0D5J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1736674:APS56 RS09215
gene id: 1736674:APS56_RS09215
uniprot id: A0A0P0CLI1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1736674:APS56 RS13715
gene id: 1736674:APS56_RS13715
uniprot id: A0A0P0CIT3
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

1736674:APS56 RS08560
gene id: 1736674:APS56_RS08560
uniprot id: A0A0P0CG75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1736674:APS56 RS14710
gene id: 1736674:APS56_RS14710
uniprot id: A0A0N7HYV5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1736674:APS56 RS00250
gene id: 1736674:APS56_RS00250
uniprot id: A0A0P0D7F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS13410
gene id: 1736674:APS56_RS13410
uniprot id: A0A0P0D556
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS14185
gene id: 1736674:APS56_RS14185
uniprot id: A0A0P0DDT6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1736674:APS56 RS10675
gene id: 1736674:APS56_RS10675
uniprot id: A0A0P0DBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1736674:APS56 RS00665
gene id: 1736674:APS56_RS00665
uniprot id: A0A0N7HXY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS01595
gene id: 1736674:APS56_RS01595
uniprot id: A0A0P0D2B5
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS03930
gene id: 1736674:APS56_RS03930
uniprot id: A0A0N7HY59
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS16155
gene id: 1736674:APS56_RS16155
uniprot id: A0A0P0D8W2
names: Similarity
messages: Belongs to the ArsC family.

1736674:APS56 RS00725
gene id: 1736674:APS56_RS00725
uniprot id: A0A0P0D5A3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1736674:APS56 RS12880
gene id: 1736674:APS56_RS12880
uniprot id: A0A0P0DD67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1736674:APS56 RS07255
gene id: 1736674:APS56_RS07255
uniprot id: A0A0P0DAN2
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS09725
gene id: 1736674:APS56_RS09725
uniprot id: A0A0P0D375
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS01940
gene id: 1736674:APS56_RS01940
uniprot id: A0A0P0CI07
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1736674:APS56 RS08610
gene id: 1736674:APS56_RS08610
uniprot id: A0A0P0CGF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1736674:APS56 RS06380
gene id: 1736674:APS56_RS06380
uniprot id: A0A0P0CF67
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1736674:APS56 RS07065
gene id: 1736674:APS56_RS07065
uniprot id: A0A0P0DA67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1736674:APS56 RS03925
gene id: 1736674:APS56_RS03925
uniprot id: A0A0P0D0N1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1736674:APS56 RS04330
gene id: 1736674:APS56_RS04330
uniprot id: A0A0P0D0R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1736674:APS56 RS00065
gene id: 1736674:APS56_RS00065
uniprot id: A0A0P0D7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS14065
gene id: 1736674:APS56_RS14065
uniprot id: A0A0P0DDR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1736674:APS56 RS15565
gene id: 1736674:APS56_RS15565
uniprot id: A0A0P0DEI7
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS12130
gene id: 1736674:APS56_RS12130
uniprot id: A0A0N7HYP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1736674:APS56 RS14280
gene id: 1736674:APS56_RS14280
uniprot id: A0A0N7HYU5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS06470
gene id: 1736674:APS56_RS06470
uniprot id: A0A0P0CWB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1736674:APS56 RS04960
gene id: 1736674:APS56_RS04960
uniprot id: A0A0P0D9G3
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS08085
gene id: 1736674:APS56_RS08085
uniprot id: A0A0N7HYF2
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1736674:APS56 RS10745
gene id: 1736674:APS56_RS10745
uniprot id: A0A0P0CHD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1736674:APS56 RS02035
gene id: 1736674:APS56_RS02035
uniprot id: A0A0N7HY17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1736674:APS56 RS03025
gene id: 1736674:APS56_RS03025
uniprot id: A0A0P0D0E7
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1736674:APS56 RS10580
gene id: 1736674:APS56_RS10580
uniprot id: A0A0P0DCY4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS10820
gene id: 1736674:APS56_RS10820
uniprot id: A0A0P0CY91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1736674:APS56 RS00560
gene id: 1736674:APS56_RS00560
uniprot id: A0A0P0CCN4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1736674:APS56 RS15270
gene id: 1736674:APS56_RS15270
uniprot id: A0A0P0DBV6
names: Similarity
messages: Belongs to the CarB family.

1736674:APS56 RS03575
gene id: 1736674:APS56_RS03575
uniprot id: A0A0P0D6F7
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1736674:APS56 RS12435
gene id: 1736674:APS56_RS12435
uniprot id: A0A0P0DAH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1736674:APS56 RS02420
gene id: 1736674:APS56_RS02420
uniprot id: A0A0N7HY26
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS03915
gene id: 1736674:APS56_RS03915
uniprot id: A0A0P0CVB4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1736674:APS56 RS13830
gene id: 1736674:APS56_RS13830
uniprot id: A0A0P0CIW2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1736674:APS56 RS01935
gene id: 1736674:APS56_RS01935
uniprot id: A0A0P0D050
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS11450
gene id: 1736674:APS56_RS11450
uniprot id: A0A0P0CMG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1736674:APS56 RS03665
gene id: 1736674:APS56_RS03665
uniprot id: A0A0P0CDY8
names: Similarity
messages: Belongs to the RutC family.

1736674:APS56 RS07355
gene id: 1736674:APS56_RS07355
uniprot id: A0A0P0D486
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1736674:APS56 RS14605
gene id: 1736674:APS56_RS14605
uniprot id: A0A0P0DDR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS04170
gene id: 1736674:APS56_RS04170
uniprot id: A0A0P0D9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1736674:APS56 RS13260
gene id: 1736674:APS56_RS13260
uniprot id: A0A0P0DDC8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1736674:APS56 RS08470
gene id: 1736674:APS56_RS08470
uniprot id: A0A0P0D8P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1736674:APS56 RS10175
gene id: 1736674:APS56_RS10175
uniprot id: A0A0P0D3E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1736674:APS56 RS12260
gene id: 1736674:APS56_RS12260
uniprot id: A0A0N7HYP8
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS07960
gene id: 1736674:APS56_RS07960
uniprot id: A0A0P0D4G9
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1736674:APS56 RS00545
gene id: 1736674:APS56_RS00545
uniprot id: A0A0P0D7I9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1736674:APS56 RS09780
gene id: 1736674:APS56_RS09780
uniprot id: A0A0N7HYJ0
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS11800
gene id: 1736674:APS56_RS11800
uniprot id: A0A0N7HYN7
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1736674:APS56 RS14760
gene id: 1736674:APS56_RS14760
uniprot id: A0A0P0D5V7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS02080
gene id: 1736674:APS56_RS02080
uniprot id: A0A0N7HY18
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1736674:APS56 RS10750
gene id: 1736674:APS56_RS10750
uniprot id: A0A0P0DC67
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1736674:APS56 RS07810
gene id: 1736674:APS56_RS07810
uniprot id: A0A0P0CFU5
names: Subcellular Location Annotation
messages: Secreted

1736674:APS56 RS03570
gene id: 1736674:APS56_RS03570
uniprot id: A0A0P0CIT9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS07585
gene id: 1736674:APS56_RS07585
uniprot id: A0A0P0CQ30
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS16335
gene id: 1736674:APS56_RS16335
uniprot id: A0A0N7HYZ2
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1736674:APS56 RS08770
gene id: 1736674:APS56_RS08770
uniprot id: A0A0P0CQV9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS13665
gene id: 1736674:APS56_RS13665
uniprot id: A0A0P0CZM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1736674:APS56 RS08570
gene id: 1736674:APS56_RS08570
uniprot id: A0A0N7HYG3
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1736674:APS56 RS11615
gene id: 1736674:APS56_RS11615
uniprot id: A0A0P0CHT2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1736674:APS56 RS10480
gene id: 1736674:APS56_RS10480
uniprot id: A0A0P0CM34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1736674:APS56 RS12710
gene id: 1736674:APS56_RS12710
uniprot id: A0A0P0CZ86
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS14300
gene id: 1736674:APS56_RS14300
uniprot id: A0A0P0DDV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1736674:APS56 RS15745
gene id: 1736674:APS56_RS15745
uniprot id: A0A0P0CJU6
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS03700
gene id: 1736674:APS56_RS03700
uniprot id: A0A0P0D6H9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS16610
gene id: 1736674:APS56_RS16610
uniprot id: A0A0P0CKA6
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1736674:APS56 RS10915
gene id: 1736674:APS56_RS10915
uniprot id: A0A0P0CHF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1736674:APS56 RS13955
gene id: 1736674:APS56_RS13955
uniprot id: A0A0N7HYT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1736674:APS56 RS12335
gene id: 1736674:APS56_RS12335
uniprot id: A0A0P0CI62
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1736674:APS56 RS06090
gene id: 1736674:APS56_RS06090
uniprot id: A0A0P0D9U9
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS00525
gene id: 1736674:APS56_RS00525
uniprot id: A0A0P0CHG0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1736674:APS56 RS14705
gene id: 1736674:APS56_RS14705
uniprot id: A0A0P0DBK8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1736674:APS56 RS09490
gene id: 1736674:APS56_RS09490
uniprot id: A0A0P0CGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1736674:APS56 RS11475
gene id: 1736674:APS56_RS11475
uniprot id: A0A0P0CHQ4
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1736674:APS56 RS02460
gene id: 1736674:APS56_RS02460
uniprot id: A0A0N7HY27
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1736674:APS56 RS03140
gene id: 1736674:APS56_RS03140
uniprot id: A0A0P0CDS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

1736674:APS56 RS00800
gene id: 1736674:APS56_RS00800
uniprot id: A0A0P0D7M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1736674:APS56 RS04035
gene id: 1736674:APS56_RS04035
uniprot id: A0A0P0D9B6
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS11100
gene id: 1736674:APS56_RS11100
uniprot id: A0A0P0DCD4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1736674:APS56 RS05815
gene id: 1736674:APS56_RS05815
uniprot id: A0A0N7HYA1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1736674:APS56 RS11185
gene id: 1736674:APS56_RS11185
uniprot id: A0A0P0D3V8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1736674:APS56 RS06720
gene id: 1736674:APS56_RS06720
uniprot id: A0A0P0D1T2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1736674:APS56 RS11880
gene id: 1736674:APS56_RS11880
uniprot id: A0A0N7HYN9
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1736674:APS56 RS16450
gene id: 1736674:APS56_RS16450
uniprot id: A0A0P0CQA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS10440
gene id: 1736674:APS56_RS10440
uniprot id: A0A0P0DBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1736674:APS56 RS05795
gene id: 1736674:APS56_RS05795
uniprot id: A0A0P0D7H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1736674:APS56 RS09610
gene id: 1736674:APS56_RS09610
uniprot id: A0A0P0CGU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1736674:APS56 RS12315
gene id: 1736674:APS56_RS12315
uniprot id: A0A0P0D6V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1736674:APS56 RS05655
gene id: 1736674:APS56_RS05655
uniprot id: A0A0P0CP48
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1736674:APS56 RS04215
gene id: 1736674:APS56_RS04215
uniprot id: A0A0P0D162
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1736674:APS56 RS14840
gene id: 1736674:APS56_RS14840
uniprot id: A0A0P0DDX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1736674:APS56 RS10830
gene id: 1736674:APS56_RS10830
uniprot id: A0A0P0D3N8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1736674:APS56 RS14120
gene id: 1736674:APS56_RS14120
uniprot id: A0A0P0CJ27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1736674:APS56 RS07200
gene id: 1736674:APS56_RS07200
uniprot id: A0A0P0DAM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1736674:APS56 RS00520
gene id: 1736674:APS56_RS00520
uniprot id: A0A0P0CZP6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1736674:APS56 RS07380
gene id: 1736674:APS56_RS07380
uniprot id: A0A0P0CWR3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1736674:APS56 RS04495
gene id: 1736674:APS56_RS04495
uniprot id: A0A0P0CVK7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1736674:APS56 RS01675
gene id: 1736674:APS56_RS01675
uniprot id: A0A0P0CDF0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS05170
gene id: 1736674:APS56_RS05170
uniprot id: A0A0P0D9T0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1736674:APS56 RS07260
gene id: 1736674:APS56_RS07260
uniprot id: A0A0P0CFK4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1736674:APS56 RS04220
gene id: 1736674:APS56_RS04220
uniprot id: A0A0P0CUV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

1736674:APS56 RS02030
gene id: 1736674:APS56_RS02030
uniprot id: A0A0P0D8G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1736674:APS56 RS02885
gene id: 1736674:APS56_RS02885
uniprot id: A0A0P0CUW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1736674:APS56 RS11625
gene id: 1736674:APS56_RS11625
uniprot id: A0A0P0CQV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1736674:APS56 RS06730
gene id: 1736674:APS56_RS06730
uniprot id: A0A0P0D7Z2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1736674:APS56 RS05505
gene id: 1736674:APS56_RS05505
uniprot id: A0A0P0CVZ8
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1736674:APS56 RS13190
gene id: 1736674:APS56_RS13190
uniprot id: A0A0P0CIJ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1736674:APS56 RS09435
gene id: 1736674:APS56_RS09435
uniprot id: A0A0P0CXN2
names: Similarity
messages: Belongs to the glutamate synthase family.

1736674:APS56 RS06240
gene id: 1736674:APS56_RS06240
uniprot id: A0A0P0CF42
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS01455
gene id: 1736674:APS56_RS01455
uniprot id: A0A0P0CHU2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1736674:APS56 RS02600
gene id: 1736674:APS56_RS02600
uniprot id: A0A0P0D8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1736674:APS56 RS16560
gene id: 1736674:APS56_RS16560
uniprot id: A0A0P0D0Z0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1736674:APS56 RS05660
gene id: 1736674:APS56_RS05660
uniprot id: A0A0P0D1A8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1736674:APS56 RS00205
gene id: 1736674:APS56_RS00205
uniprot id: A0A0P0D7S5
names: Similarity
messages: Belongs to the peptidase S49 family.

1736674:APS56 RS00865
gene id: 1736674:APS56_RS00865
uniprot id: A0A0P0D813
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1736674:APS56 RS02065
gene id: 1736674:APS56_RS02065
uniprot id: A0A0P0CI27
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1736674:APS56 RS03295
gene id: 1736674:APS56_RS03295
uniprot id: A0A0P0D0H3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1736674:APS56 RS00215
gene id: 1736674:APS56_RS00215
uniprot id: A0A0P0CTN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1736674:APS56 RS14765
gene id: 1736674:APS56_RS14765
uniprot id: A0A0P0CPC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1736674:APS56 RS16355
gene id: 1736674:APS56_RS16355
uniprot id: A0A0P0CK44
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1736674:APS56 RS13780
gene id: 1736674:APS56_RS13780
uniprot id: A0A0P0CIU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1736674:APS56 RS03255
gene id: 1736674:APS56_RS03255
uniprot id: A0A0P0D2V4
names: Similarity
messages: Belongs to the peptidase C40 family.

1736674:APS56 RS14540
gene id: 1736674:APS56_RS14540
uniprot id: A0A0N7HYV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1736674:APS56 RS03030
gene id: 1736674:APS56_RS03030
uniprot id: A0A0N7HY39
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS11145
gene id: 1736674:APS56_RS11145
uniprot id: A0A0P0D6B0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1736674:APS56 RS03610
gene id: 1736674:APS56_RS03610
uniprot id: A0A0P0CDY0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1736674:APS56 RS10890
gene id: 1736674:APS56_RS10890
uniprot id: A0A0P0D3Q7
names: Similarity
messages: Belongs to the Skp family.

1736674:APS56 RS08465
gene id: 1736674:APS56_RS08465
uniprot id: A0A0P0CL55
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS15510
gene id: 1736674:APS56_RS15510
uniprot id: A0A0P0D0I7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1736674:APS56 RS08785
gene id: 1736674:APS56_RS08785
uniprot id: A0A0P0D8U6
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS07910
gene id: 1736674:APS56_RS07910
uniprot id: A0A0P0DAI7
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1736674:APS56 RS14075
gene id: 1736674:APS56_RS14075
uniprot id: A0A0N7HYU0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1736674:APS56 RS11320
gene id: 1736674:APS56_RS11320
uniprot id: A0A0N7HYM6
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS01360
gene id: 1736674:APS56_RS01360
uniprot id: A0A0P0D878
names: Similarity
messages: Belongs to the CvfB family.

1736674:APS56 RS02440
gene id: 1736674:APS56_RS02440
uniprot id: A0A0P0D2M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1736674:APS56 RS09260
gene id: 1736674:APS56_RS09260
uniprot id: A0A0P0CR55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1736674:APS56 RS05525
gene id: 1736674:APS56_RS05525
uniprot id: A0A0P0D7B9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1736674:APS56 RS03305
gene id: 1736674:APS56_RS03305
uniprot id: A0A0P0D6B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1736674:APS56 RS13620
gene id: 1736674:APS56_RS13620
uniprot id: A0A0N7HYS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1736674:APS56 RS12455
gene id: 1736674:APS56_RS12455
uniprot id: A0A0P0DD00
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1736674:APS56 RS11435
gene id: 1736674:APS56_RS11435
uniprot id: A0A0P0CS95
names: Similarity
messages: Belongs to the pyruvate kinase family.

1736674:APS56 RS01655
gene id: 1736674:APS56_RS01655
uniprot id: A0A0P0D2C3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1736674:APS56 RS06340
gene id: 1736674:APS56_RS06340
uniprot id: A0A0P0CK33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS04295
gene id: 1736674:APS56_RS04295
uniprot id: A0A0P0D937
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1736674:APS56 RS09530
gene id: 1736674:APS56_RS09530
uniprot id: A0A0P0D5G2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1736674:APS56 RS04540
gene id: 1736674:APS56_RS04540
uniprot id: A0A0P0D9I5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1736674:APS56 RS14950
gene id: 1736674:APS56_RS14950
uniprot id: A0A0P0DE01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS08515
gene id: 1736674:APS56_RS08515
uniprot id: A0A0P0D2J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS05970
gene id: 1736674:APS56_RS05970
uniprot id: A0A0P0D1G9
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1736674:APS56 RS09345
gene id: 1736674:APS56_RS09345
uniprot id: A0A0P0D583
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1736674:APS56 RS03895
gene id: 1736674:APS56_RS03895
uniprot id: A0A0P0D8Y4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1736674:APS56 RS04880
gene id: 1736674:APS56_RS04880
uniprot id: A0A0P0D0X9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1736674:APS56 RS10465
gene id: 1736674:APS56_RS10465
uniprot id: A0A0P0CRR8
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1736674:APS56 RS10485
gene id: 1736674:APS56_RS10485
uniprot id: A0A0P0D9K5
names: Subunit
messages: Homodimer.

1736674:APS56 RS03460
gene id: 1736674:APS56_RS03460
uniprot id: A0A0N7HY48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1736674:APS56 RS15430
gene id: 1736674:APS56_RS15430
uniprot id: A0A0P0CJM9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1736674:APS56 RS02110
gene id: 1736674:APS56_RS02110
uniprot id: A0A0P0CML9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1736674:APS56 RS06565
gene id: 1736674:APS56_RS06565
uniprot id: A0A0P0D1A0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1736674:APS56 RS02925
gene id: 1736674:APS56_RS02925
uniprot id: A0A0P0D8J8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1736674:APS56 RS08210
gene id: 1736674:APS56_RS08210
uniprot id: A0A0P0CL22
names: Similarity
messages: Belongs to the MreC family.

1736674:APS56 RS16280
gene id: 1736674:APS56_RS16280
uniprot id: A0A0P0D8Y3
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1736674:APS56 RS07335
gene id: 1736674:APS56_RS07335
uniprot id: A0A0P0D208
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1736674:APS56 RS01300
gene id: 1736674:APS56_RS01300
uniprot id: A0A0P0D872
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1736674:APS56 RS04325
gene id: 1736674:APS56_RS04325
uniprot id: A0A0P0CNK5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1736674:APS56 RS12605
gene id: 1736674:APS56_RS12605
uniprot id: A0A0P0CN64
names: Similarity
messages: Belongs to the thioredoxin family.

1736674:APS56 RS15305
gene id: 1736674:APS56_RS15305
uniprot id: A0A0P0D0F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1736674:APS56 RS01900
gene id: 1736674:APS56_RS01900
uniprot id: A0A0P0D846
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS08275
gene id: 1736674:APS56_RS08275
uniprot id: A0A0P0CL36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1736674:APS56 RS03875
gene id: 1736674:APS56_RS03875
uniprot id: A0A0P0CIZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1736674:APS56 RS16150
gene id: 1736674:APS56_RS16150
uniprot id: A0A0P0DC86
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS00790
gene id: 1736674:APS56_RS00790
uniprot id: A0A0P0D1Y2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1736674:APS56 RS03745
gene id: 1736674:APS56_RS03745
uniprot id: A0A0P0CNB3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1736674:APS56 RS03830
gene id: 1736674:APS56_RS03830
uniprot id: A0A0P0D326
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1736674:APS56 RS11735
gene id: 1736674:APS56_RS11735
uniprot id: A0A0P0DCY9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1736674:APS56 RS05385
gene id: 1736674:APS56_RS05385
uniprot id: A0A0P0DCQ1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1736674:APS56 RS07265
gene id: 1736674:APS56_RS07265
uniprot id: A0A0P0CWP6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1736674:APS56 RS02390
gene id: 1736674:APS56_RS02390
uniprot id: A0A0P0D8A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1736674:APS56 RS10155
gene id: 1736674:APS56_RS10155
uniprot id: A0A0P0CV59
names: Similarity
messages: Belongs to the ArsC family.

1736674:APS56 RS13170
gene id: 1736674:APS56_RS13170
uniprot id: A0A0P0CNI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1736674:APS56 RS10300
gene id: 1736674:APS56_RS10300
uniprot id: A0A0P0D3F9
names: Similarity
messages: Belongs to the peptidase S66 family.

1736674:APS56 RS09285
gene id: 1736674:APS56_RS09285
uniprot id: A0A0P0D917
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1736674:APS56 RS04270
gene id: 1736674:APS56_RS04270
uniprot id: A0A0P0D0Q6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1736674:APS56 RS15155
gene id: 1736674:APS56_RS15155
uniprot id: A0A0N7HYW5
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS14885
gene id: 1736674:APS56_RS14885
uniprot id: A0A0P0DBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS09175
gene id: 1736674:APS56_RS09175
uniprot id: A0A0P0DB33
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS00565
gene id: 1736674:APS56_RS00565
uniprot id: A0A0P0CTT0
names: Similarity
messages: Belongs to the transketolase family.

1736674:APS56 RS12960
gene id: 1736674:APS56_RS12960
uniprot id: A0A0P0CZC7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1736674:APS56 RS13440
gene id: 1736674:APS56_RS13440
uniprot id: A0A0P0DD35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1736674:APS56 RS12100
gene id: 1736674:APS56_RS12100
uniprot id: A0A0P0CI09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1736674:APS56 RS08960
gene id: 1736674:APS56_RS08960
uniprot id: A0A0P0CLB9
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1736674:APS56 RS07625
gene id: 1736674:APS56_RS07625
uniprot id: A0A0P0DAU5
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS16530
gene id: 1736674:APS56_RS16530
uniprot id: A0A0P0D924
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1736674:APS56 RS10120
gene id: 1736674:APS56_RS10120
uniprot id: A0A0P0D5R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS09520
gene id: 1736674:APS56_RS09520
uniprot id: A0A0N7HYI5
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS05075
gene id: 1736674:APS56_RS05075
uniprot id: A0A0P0CJJ2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1736674:APS56 RS16615
gene id: 1736674:APS56_RS16615
uniprot id: A0A0P0D101
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

1736674:APS56 RS12305
gene id: 1736674:APS56_RS12305
uniprot id: A0A0P0CMX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1736674:APS56 RS00585
gene id: 1736674:APS56_RS00585
uniprot id: A0A0P0CLY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS02130
gene id: 1736674:APS56_RS02130
uniprot id: A0A0P0D5T0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1736674:APS56 RS01855
gene id: 1736674:APS56_RS01855
uniprot id: A0A0P0D8E4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1736674:APS56 RS03145
gene id: 1736674:APS56_RS03145
uniprot id: A0A0P0CUZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1736674:APS56 RS11885
gene id: 1736674:APS56_RS11885
uniprot id: A0A0P0CMP7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1736674:APS56 RS11060
gene id: 1736674:APS56_RS11060
uniprot id: A0A0P0CS35
names: Similarity
messages: Belongs to the peptidase S8 family.

1736674:APS56 RS11130
gene id: 1736674:APS56_RS11130
uniprot id: A0A0N7HYM2
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS02950
gene id: 1736674:APS56_RS02950
uniprot id: A0A0P0CUX0
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1736674:APS56 RS12600
gene id: 1736674:APS56_RS12600
uniprot id: A0A0P0D4N8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1736674:APS56 RS02005
gene id: 1736674:APS56_RS02005
uniprot id: A0A0P0CI15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1736674:APS56 RS11240
gene id: 1736674:APS56_RS11240
uniprot id: A0A0P0CYG9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS07475
gene id: 1736674:APS56_RS07475
uniprot id: A0A0P0D499
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1736674:APS56 RS14080
gene id: 1736674:APS56_RS14080
uniprot id: A0A0P0CZU5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1736674:APS56 RS12235
gene id: 1736674:APS56_RS12235
uniprot id: A0A0P0CSP3
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1736674:APS56 RS09045
gene id: 1736674:APS56_RS09045
uniprot id: A0A0P0CLC9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1736674:APS56 RS12890
gene id: 1736674:APS56_RS12890
uniprot id: A0A0P0CZB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1736674:APS56 RS06345
gene id: 1736674:APS56_RS06345
uniprot id: A0A0N7HYB2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1736674:APS56 RS07450
gene id: 1736674:APS56_RS07450
uniprot id: A0A0P0CWS3
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1736674:APS56 RS09930
gene id: 1736674:APS56_RS09930
uniprot id: A0A0P0CLU1
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS15855
gene id: 1736674:APS56_RS15855
uniprot id: A0A0N7HYY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS04010
gene id: 1736674:APS56_RS04010
uniprot id: A0A0P0DF10
names: Similarity
messages: Belongs to the UPF0047 family.

1736674:APS56 RS04945
gene id: 1736674:APS56_RS04945
uniprot id: A0A0N7HY82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1736674:APS56 RS07480
gene id: 1736674:APS56_RS07480
uniprot id: A0A0N7HYD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1736674:APS56 RS13060
gene id: 1736674:APS56_RS13060
uniprot id: A0A0P0DD98
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS15860
gene id: 1736674:APS56_RS15860
uniprot id: A0A0P0CJV5
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1736674:APS56 RS09315
gene id: 1736674:APS56_RS09315
uniprot id: A0A0N7HYI0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS15760
gene id: 1736674:APS56_RS15760
uniprot id: A0A0P0D6F1
names: Similarity
messages: Belongs to the peptidase M16 family.

1736674:APS56 RS04055
gene id: 1736674:APS56_RS04055
uniprot id: A0A0P0CNG8
names: Similarity
messages: Belongs to the HSP15 family.

1736674:APS56 RS05515
gene id: 1736674:APS56_RS05515
uniprot id: A0A0P0D185
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1736674:APS56 RS06390
gene id: 1736674:APS56_RS06390
uniprot id: A0A0N7HYB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1736674:APS56 RS14045
gene id: 1736674:APS56_RS14045
uniprot id: A0A0P0DB92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1736674:APS56 RS06495
gene id: 1736674:APS56_RS06495
uniprot id: A0A0N7HYB5
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1736674:APS56 RS07570
gene id: 1736674:APS56_RS07570
uniprot id: A0A0N7HYE0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1736674:APS56 RS08400
gene id: 1736674:APS56_RS08400
uniprot id: A0A0P0CL50
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1736674:APS56 RS12480
gene id: 1736674:APS56_RS12480
uniprot id: A0A0P0CSU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1736674:APS56 RS15580
gene id: 1736674:APS56_RS15580
uniprot id: A0A0P0CU78
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1736674:APS56 RS05030
gene id: 1736674:APS56_RS05030
uniprot id: A0A0P0D9R2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1736674:APS56 RS13085
gene id: 1736674:APS56_RS13085
uniprot id: A0A0P0CT32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1736674:APS56 RS16220
gene id: 1736674:APS56_RS16220
uniprot id: A0A0P0DC98
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS12540
gene id: 1736674:APS56_RS12540
uniprot id: A0A0P0D4L4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1736674:APS56 RS16555
gene id: 1736674:APS56_RS16555
uniprot id: A0A0P0CK98
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1736674:APS56 RS06255
gene id: 1736674:APS56_RS06255
uniprot id: A0A0P0CPF6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS08455
gene id: 1736674:APS56_RS08455
uniprot id: A0A0P0CQQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1736674:APS56 RS06475
gene id: 1736674:APS56_RS06475
uniprot id: A0A0P0CPK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1736674:APS56 RS13415
gene id: 1736674:APS56_RS13415
uniprot id: A0A0P0CKP8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1736674:APS56 RS00075
gene id: 1736674:APS56_RS00075
uniprot id: A0A0P0CCT1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1736674:APS56 RS08025
gene id: 1736674:APS56_RS08025
uniprot id: A0A0P0D4I2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1736674:APS56 RS02880
gene id: 1736674:APS56_RS02880
uniprot id: A0A0P0CDN7
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS14580
gene id: 1736674:APS56_RS14580
uniprot id: A0A0P0D5T4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1736674:APS56 RS13450
gene id: 1736674:APS56_RS13450
uniprot id: A0A0P0DDF4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1736674:APS56 RS14450
gene id: 1736674:APS56_RS14450
uniprot id: A0A0N7HYU9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1736674:APS56 RS14695
gene id: 1736674:APS56_RS14695
uniprot id: A0A0P0D5U9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1736674:APS56 RS13640
gene id: 1736674:APS56_RS13640
uniprot id: A0A0P0DD83
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1736674:APS56 RS13950
gene id: 1736674:APS56_RS13950
uniprot id: A0A0P0DDN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1736674:APS56 RS14610
gene id: 1736674:APS56_RS14610
uniprot id: A0A0P0CJ95
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS10865
gene id: 1736674:APS56_RS10865
uniprot id: A0A0P0DC95
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1736674:APS56 RS10815
gene id: 1736674:APS56_RS10815
uniprot id: A0A0P0CHB6
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1736674:APS56 RS02815
gene id: 1736674:APS56_RS02815
uniprot id: A0A0P0CUV3
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1736674:APS56 RS12545
gene id: 1736674:APS56_RS12545
uniprot id: A0A0P0CN46
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1736674:APS56 RS13175
gene id: 1736674:APS56_RS13175
uniprot id: A0A0P0DAV1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS05135
gene id: 1736674:APS56_RS05135
uniprot id: A0A0N7HY86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1736674:APS56 RS12930
gene id: 1736674:APS56_RS12930
uniprot id: A0A0P0D757
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1736674:APS56 RS02780
gene id: 1736674:APS56_RS02780
uniprot id: A0A0P0CDW2
names: Similarity
messages: Belongs to the HsdR family.

1736674:APS56 RS03075
gene id: 1736674:APS56_RS03075
uniprot id: A0A0P0CDR9
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1736674:APS56 RS13610
gene id: 1736674:APS56_RS13610
uniprot id: A0A0P0CTC3
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1736674:APS56 RS16225
gene id: 1736674:APS56_RS16225
uniprot id: A0A0P0D8X2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1736674:APS56 RS15600
gene id: 1736674:APS56_RS15600
uniprot id: A0A0N7HYX5
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS03345
gene id: 1736674:APS56_RS03345
uniprot id: A0A0P0CV22
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1736674:APS56 RS10210
gene id: 1736674:APS56_RS10210
uniprot id: A0A0P0DBX7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1736674:APS56 RS05085
gene id: 1736674:APS56_RS05085
uniprot id: A0A0N7HY85
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS04985
gene id: 1736674:APS56_RS04985
uniprot id: A0A0N7HY83
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS10030
gene id: 1736674:APS56_RS10030
uniprot id: A0A0P0CGX5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1736674:APS56 RS11020
gene id: 1736674:APS56_RS11020
uniprot id: A0A0P0D9S7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1736674:APS56 RS05060
gene id: 1736674:APS56_RS05060
uniprot id: A0A0P0CKH9
names: Similarity
messages: Belongs to the AIR synthase family.

1736674:APS56 RS10530
gene id: 1736674:APS56_RS10530
uniprot id: A0A0P0D3I3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1736674:APS56 RS02910
gene id: 1736674:APS56_RS02910
uniprot id: A0A0P0CID8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1736674:APS56 RS05155
gene id: 1736674:APS56_RS05155
uniprot id: A0A0P0D3K2
names: Subcellular Location Annotation
messages: Nucleus

1736674:APS56 RS09415
gene id: 1736674:APS56_RS09415
uniprot id: A0A0P0DB72
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1736674:APS56 RS05605
gene id: 1736674:APS56_RS05605
uniprot id: A0A0P0CJS9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1736674:APS56 RS11915
gene id: 1736674:APS56_RS11915
uniprot id: A0A0P0CHX9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1736674:APS56 RS11195
gene id: 1736674:APS56_RS11195
uniprot id: A0A0P0D9V0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1736674:APS56 RS09475
gene id: 1736674:APS56_RS09475
uniprot id: A0A0P0CGS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1736674:APS56 RS00335
gene id: 1736674:APS56_RS00335
uniprot id: A0A0P0CCJ9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1736674:APS56 RS13685
gene id: 1736674:APS56_RS13685
uniprot id: A0A0P0DB27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1736674:APS56 RS12955
gene id: 1736674:APS56_RS12955
uniprot id: A0A0P0CIH9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1736674:APS56 RS14030
gene id: 1736674:APS56_RS14030
uniprot id: A0A0P0D5J0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1736674:APS56 RS10885
gene id: 1736674:APS56_RS10885
uniprot id: A0A0N7HYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS00930
gene id: 1736674:APS56_RS00930
uniprot id: A0A0P0D816
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1736674:APS56 RS11255
gene id: 1736674:APS56_RS11255
uniprot id: A0A0P0CME5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS16340
gene id: 1736674:APS56_RS16340
uniprot id: A0A0P0DCB8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1736674:APS56 RS11835
gene id: 1736674:APS56_RS11835
uniprot id: A0A0P0D6L2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1736674:APS56 RS06125
gene id: 1736674:APS56_RS06125
uniprot id: A0A0P0CPD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1736674:APS56 RS16565
gene id: 1736674:APS56_RS16565
uniprot id: A0A0P0CUM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1736674:APS56 RS13645
gene id: 1736674:APS56_RS13645
uniprot id: A0A0P0CIT0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1736674:APS56 RS08090
gene id: 1736674:APS56_RS08090
uniprot id: A0A0P0D8J2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1736674:APS56 RS13470
gene id: 1736674:APS56_RS13470
uniprot id: A0A0N7HYS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1736674:APS56 RS12265
gene id: 1736674:APS56_RS12265
uniprot id: A0A0P0DCJ7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1736674:APS56 RS09310
gene id: 1736674:APS56_RS09310
uniprot id: A0A0P0CGJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS13995
gene id: 1736674:APS56_RS13995
uniprot id: A0A0N7HYT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1736674:APS56 RS14400
gene id: 1736674:APS56_RS14400
uniprot id: A0A0P0D7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1736674:APS56 RS00170
gene id: 1736674:APS56_RS00170
uniprot id: A0A0P0CZJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1736674:APS56 RS10095
gene id: 1736674:APS56_RS10095
uniprot id: A0A0P0CXX7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1736674:APS56 RS10905
gene id: 1736674:APS56_RS10905
uniprot id: A0A0P0D671
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1736674:APS56 RS08720
gene id: 1736674:APS56_RS08720
uniprot id: A0A0P0CL92
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1736674:APS56 RS14990
gene id: 1736674:APS56_RS14990
uniprot id: A0A0P0D608
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1736674:APS56 RS10225
gene id: 1736674:APS56_RS10225
uniprot id: A0A0N7HYK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS04600
gene id: 1736674:APS56_RS04600
uniprot id: A0A0P0DCP2
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS09995
gene id: 1736674:APS56_RS09995
uniprot id: A0A0P0CLV3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1736674:APS56 RS06920
gene id: 1736674:APS56_RS06920
uniprot id: A0A0P0D1V0
names: Similarity
messages: Belongs to the AHA1 family.

1736674:APS56 RS02095
gene id: 1736674:APS56_RS02095
uniprot id: A0A0P0D8I2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1736674:APS56 RS05090
gene id: 1736674:APS56_RS05090
uniprot id: A0A0P0CUW6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1736674:APS56 RS11265
gene id: 1736674:APS56_RS11265
uniprot id: A0A0N7HYM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1736674:APS56 RS09265
gene id: 1736674:APS56_RS09265
uniprot id: A0A0P0D303
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS12245
gene id: 1736674:APS56_RS12245
uniprot id: A0A0P0CMW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

1736674:APS56 RS16305
gene id: 1736674:APS56_RS16305
uniprot id: A0A0P0CK52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1736674:APS56 RS01450
gene id: 1736674:APS56_RS01450
uniprot id: A0A0P0D005
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1736674:APS56 RS10965
gene id: 1736674:APS56_RS10965
uniprot id: A0A0N7HYL8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1736674:APS56 RS07275
gene id: 1736674:APS56_RS07275
uniprot id: A0A0P0CPY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1736674:APS56 RS12090
gene id: 1736674:APS56_RS12090
uniprot id: A0A0N7HYP4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1736674:APS56 RS05180
gene id: 1736674:APS56_RS05180
uniprot id: A0A0P0CEK7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1736674:APS56 RS14380
gene id: 1736674:APS56_RS14380
uniprot id: A0A0P0D5N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1736674:APS56 RS00180
gene id: 1736674:APS56_RS00180
uniprot id: A0A0P0D525
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1736674:APS56 RS16550
gene id: 1736674:APS56_RS16550
uniprot id: A0A0N7HYZ7
names: Similarity
messages: Belongs to the CinA family.

1736674:APS56 RS14050
gene id: 1736674:APS56_RS14050
uniprot id: A0A0P0D7T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1736674:APS56 RS11380
gene id: 1736674:APS56_RS11380
uniprot id: A0A0P0CS83
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1736674:APS56 RS15120
gene id: 1736674:APS56_RS15120
uniprot id: A0A0P0CJI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS13700
gene id: 1736674:APS56_RS13700
uniprot id: A0A0N7HYT1
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS11415
gene id: 1736674:APS56_RS11415
uniprot id: A0A0P0CHP4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1736674:APS56 RS08195
gene id: 1736674:APS56_RS08195
uniprot id: A0A0P0CX46
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS05440
gene id: 1736674:APS56_RS05440
uniprot id: A0A0N7HY93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1736674:APS56 RS08290
gene id: 1736674:APS56_RS08290
uniprot id: A0A0P0DAP8
names: Similarity
messages: Belongs to the Dps family.

1736674:APS56 RS15480
gene id: 1736674:APS56_RS15480
uniprot id: A0A0P0D8J6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1736674:APS56 RS13975
gene id: 1736674:APS56_RS13975
uniprot id: A0A0P0D5I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1736674:APS56 RS04420
gene id: 1736674:APS56_RS04420
uniprot id: A0A0P0CEL7
names: Similarity
messages: Belongs to the group II decarboxylase family.

1736674:APS56 RS07090
gene id: 1736674:APS56_RS07090
uniprot id: A0A0P0CPV8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS01925
gene id: 1736674:APS56_RS01925
uniprot id: A0A0P0CUH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1736674:APS56 RS10125
gene id: 1736674:APS56_RS10125
uniprot id: A0A0N7HYJ8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1736674:APS56 RS03265
gene id: 1736674:APS56_RS03265
uniprot id: A0A0P0CE39
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1736674:APS56 RS08650
gene id: 1736674:APS56_RS08650
uniprot id: A0A0P0CL85
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1736674:APS56 RS13130
gene id: 1736674:APS56_RS13130
uniprot id: A0A0P0CIJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1736674:APS56 RS00895
gene id: 1736674:APS56_RS00895
uniprot id: A0A0P0CHM0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1736674:APS56 RS08190
gene id: 1736674:APS56_RS08190
uniprot id: A0A0N7HZ15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1736674:APS56 RS10595
gene id: 1736674:APS56_RS10595
uniprot id: A0A0P0D3I9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1736674:APS56 RS05020
gene id: 1736674:APS56_RS05020
uniprot id: A0A0P0CEW8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1736674:APS56 RS14305
gene id: 1736674:APS56_RS14305
uniprot id: A0A0P0CJ42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1736674:APS56 RS11605
gene id: 1736674:APS56_RS11605
uniprot id: A0A0P0DCK6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1736674:APS56 RS08460
gene id: 1736674:APS56_RS08460
uniprot id: A0A0P0D2I4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS12500
gene id: 1736674:APS56_RS12500
uniprot id: A0A0P0D6Z4
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1736674:APS56 RS04315
gene id: 1736674:APS56_RS04315
uniprot id: A0A0P0CE85
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS10615
gene id: 1736674:APS56_RS10615
uniprot id: A0A0P0D606
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1736674:APS56 RS03820
gene id: 1736674:APS56_RS03820
uniprot id: A0A0P0CIY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS09445
gene id: 1736674:APS56_RS09445
uniprot id: A0A0P0CR85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS01800
gene id: 1736674:APS56_RS01800
uniprot id: A0A0P0CD81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1736674:APS56 RS11105
gene id: 1736674:APS56_RS11105
uniprot id: A0A0P0CHJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1736674:APS56 RS15190
gene id: 1736674:APS56_RS15190
uniprot id: A0A0P0CU19
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS07575
gene id: 1736674:APS56_RS07575
uniprot id: A0A0P0DFC8
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1736674:APS56 RS11285
gene id: 1736674:APS56_RS11285
uniprot id: A0A0P0DCG5
names: Similarity
messages: Belongs to the RecJ family.

1736674:APS56 RS12525
gene id: 1736674:APS56_RS12525
uniprot id: A0A0P0CIA5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1736674:APS56 RS00040
gene id: 1736674:APS56_RS00040
uniprot id: A0A0P0CH94
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1736674:APS56 RS14025
gene id: 1736674:APS56_RS14025
uniprot id: A0A0P0CTJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1736674:APS56 RS05025
gene id: 1736674:APS56_RS05025
uniprot id: A0A0N7HY84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1736674:APS56 RS07495
gene id: 1736674:APS56_RS07495
uniprot id: A0A0P0CFW7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1736674:APS56 RS12980
gene id: 1736674:APS56_RS12980
uniprot id: A0A0P0DAS3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1736674:APS56 RS03910
gene id: 1736674:APS56_RS03910
uniprot id: A0A0P0CE30
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1736674:APS56 RS13110
gene id: 1736674:APS56_RS13110
uniprot id: A0A0N7HYR8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1736674:APS56 RS13320
gene id: 1736674:APS56_RS13320
uniprot id: A0A0P0CIM2
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

1736674:APS56 RS00860
gene id: 1736674:APS56_RS00860
uniprot id: A0A0P0CD50
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1736674:APS56 RS14780
gene id: 1736674:APS56_RS14780
uniprot id: A0A0P0DDW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1736674:APS56 RS14005
gene id: 1736674:APS56_RS14005
uniprot id: A0A0P0CIZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1736674:APS56 RS03290
gene id: 1736674:APS56_RS03290
uniprot id: A0A0P0CN53
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1736674:APS56 RS11595
gene id: 1736674:APS56_RS11595
uniprot id: A0A0P0DC90
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS03215
gene id: 1736674:APS56_RS03215
uniprot id: A0A0P0CN42
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1736674:APS56 RS06980
gene id: 1736674:APS56_RS06980
uniprot id: A0A0P0D1V3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1736674:APS56 RS05695
gene id: 1736674:APS56_RS05695
uniprot id: A0A0P0CF49
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS10535
gene id: 1736674:APS56_RS10535
uniprot id: A0A0P0CM42
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1736674:APS56 RS05210
gene id: 1736674:APS56_RS05210
uniprot id: A0A0P0D781
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1736674:APS56 RS01350
gene id: 1736674:APS56_RS01350
uniprot id: A0A0N7HY01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1736674:APS56 RS03000
gene id: 1736674:APS56_RS03000
uniprot id: A0A0P0CE00
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS14090
gene id: 1736674:APS56_RS14090
uniprot id: A0A0P0D5K1
names: Similarity
messages: Belongs to the citrate synthase family.

1736674:APS56 RS16175
gene id: 1736674:APS56_RS16175
uniprot id: A0A0P0DET4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1736674:APS56 RS08815
gene id: 1736674:APS56_RS08815
uniprot id: A0A0P0CGB4
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1736674:APS56 RS15725
gene id: 1736674:APS56_RS15725
uniprot id: A0A0N7HYX8
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS13855
gene id: 1736674:APS56_RS13855
uniprot id: A0A0P0CTG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1736674:APS56 RS03900
gene id: 1736674:APS56_RS03900
uniprot id: A0A0P0CED1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1736674:APS56 RS11545
gene id: 1736674:APS56_RS11545
uniprot id: A0A0P0DCK0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1736674:APS56 RS13895
gene id: 1736674:APS56_RS13895
uniprot id: A0A0P0DDM7
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS03840
gene id: 1736674:APS56_RS03840
uniprot id: A0A0P0CEC1
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS06740
gene id: 1736674:APS56_RS06740
uniprot id: A0A0P0DA36
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1736674:APS56 RS02975
gene id: 1736674:APS56_RS02975
uniprot id: A0A0P0D2S8
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1736674:APS56 RS05430
gene id: 1736674:APS56_RS05430
uniprot id: A0A0P0CEQ1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1736674:APS56 RS13960
gene id: 1736674:APS56_RS13960
uniprot id: A0A0P0CIX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1736674:APS56 RS11840
gene id: 1736674:APS56_RS11840
uniprot id: A0A0N7HYN8
names: Similarity
messages: Belongs to the SufE family.

1736674:APS56 RS00115
gene id: 1736674:APS56_RS00115
uniprot id: A0A0N7HXX2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1736674:APS56 RS04515
gene id: 1736674:APS56_RS04515
uniprot id: A0A0N7HY72
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1736674:APS56 RS03035
gene id: 1736674:APS56_RS03035
uniprot id: A0A0P0D6Z3
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS03205
gene id: 1736674:APS56_RS03205
uniprot id: A0A0P0CV02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1736674:APS56 RS04025
gene id: 1736674:APS56_RS04025
uniprot id: A0A0N7HY61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1736674:APS56 RS00050
gene id: 1736674:APS56_RS00050
uniprot id: A0A0P0D508
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS14865
gene id: 1736674:APS56_RS14865
uniprot id: A0A0P0CTX2
names: Similarity
messages: Belongs to the UPF0246 family.

1736674:APS56 RS16310
gene id: 1736674:APS56_RS16310
uniprot id: A0A0P0D0V8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1736674:APS56 RS02405
gene id: 1736674:APS56_RS02405
uniprot id: A0A0P0CDH4
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1736674:APS56 RS08510
gene id: 1736674:APS56_RS08510
uniprot id: A0A0P0CQR4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1736674:APS56 RS01375
gene id: 1736674:APS56_RS01375
uniprot id: A0A0P0CM97
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS10205
gene id: 1736674:APS56_RS10205
uniprot id: A0A0P0CH36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS13935
gene id: 1736674:APS56_RS13935
uniprot id: A0A0P0D7R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1736674:APS56 RS15020
gene id: 1736674:APS56_RS15020
uniprot id: A0A0P0D898
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS11705
gene id: 1736674:APS56_RS11705
uniprot id: A0A0P0DA44
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1736674:APS56 RS00325
gene id: 1736674:APS56_RS00325
uniprot id: A0A0N7HXX7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1736674:APS56 RS12465
gene id: 1736674:APS56_RS12465
uniprot id: A0A0P0CZ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1736674:APS56 RS15690
gene id: 1736674:APS56_RS15690
uniprot id: A0A0P0CJS7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1736674:APS56 RS10555
gene id: 1736674:APS56_RS10555
uniprot id: A0A0P0DBQ3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1736674:APS56 RS15315
gene id: 1736674:APS56_RS15315
uniprot id: A0A0P0D669
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS03720
gene id: 1736674:APS56_RS03720
uniprot id: A0A0N7HY54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS11925
gene id: 1736674:APS56_RS11925
uniprot id: A0A0P0CYW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS13940
gene id: 1736674:APS56_RS13940
uniprot id: A0A0P0DDD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1736674:APS56 RS03210
gene id: 1736674:APS56_RS03210
uniprot id: A0A0N7HY43
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

1736674:APS56 RS06465
gene id: 1736674:APS56_RS06465
uniprot id: A0A0P0CF79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1736674:APS56 RS07755
gene id: 1736674:APS56_RS07755
uniprot id: A0A0P0CWX4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1736674:APS56 RS02160
gene id: 1736674:APS56_RS02160
uniprot id: A0A0N7HY20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1736674:APS56 RS09605
gene id: 1736674:APS56_RS09605
uniprot id: A0A0P0D1D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1736674:APS56 RS13785
gene id: 1736674:APS56_RS13785
uniprot id: A0A0P0CZP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1736674:APS56 RS03890
gene id: 1736674:APS56_RS03890
uniprot id: A0A0N7HY58
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS00460
gene id: 1736674:APS56_RS00460
uniprot id: A0A0P0CLX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1736674:APS56 RS15710
gene id: 1736674:APS56_RS15710
uniprot id: A0A0P0CPW4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS11815
gene id: 1736674:APS56_RS11815
uniprot id: A0A0P0CSG7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1736674:APS56 RS09250
gene id: 1736674:APS56_RS09250
uniprot id: A0A0P0CGI3
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS14820
gene id: 1736674:APS56_RS14820
uniprot id: A0A0P0CPD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1736674:APS56 RS15555
gene id: 1736674:APS56_RS15555
uniprot id: A0A0P0CJP7
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS02875
gene id: 1736674:APS56_RS02875
uniprot id: A0A0P0DF52
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS03115
gene id: 1736674:APS56_RS03115
uniprot id: A0A0P0D8M5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS14570
gene id: 1736674:APS56_RS14570
uniprot id: A0A0P0CTS5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1736674:APS56 RS10060
gene id: 1736674:APS56_RS10060
uniprot id: A0A0P0D9D2
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1736674:APS56 RS05235
gene id: 1736674:APS56_RS05235
uniprot id: A0A0P0D9U3
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS08295
gene id: 1736674:APS56_RS08295
uniprot id: A0A0P0CG86
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1736674:APS56 RS12010
gene id: 1736674:APS56_RS12010
uniprot id: A0A0N7HYP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS13930
gene id: 1736674:APS56_RS13930
uniprot id: A0A0P0DB63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1736674:APS56 RS10085
gene id: 1736674:APS56_RS10085
uniprot id: A0A0N7HYJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS07145
gene id: 1736674:APS56_RS07145
uniprot id: A0A0N7HYD0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1736674:APS56 RS13805
gene id: 1736674:APS56_RS13805
uniprot id: A0A0P0D5E9
names: Similarity
messages: Belongs to the peptidase S51 family.

1736674:APS56 RS00105
gene id: 1736674:APS56_RS00105
uniprot id: A0A0P0DF16
names: Similarity
messages: Belongs to the glutamate synthase family.

1736674:APS56 RS10665
gene id: 1736674:APS56_RS10665
uniprot id: A0A0P0D9M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1736674:APS56 RS07940
gene id: 1736674:APS56_RS07940
uniprot id: A0A0P0D2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1736674:APS56 RS16640
gene id: 1736674:APS56_RS16640
uniprot id: A0A0P0DCH6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS07775
gene id: 1736674:APS56_RS07775
uniprot id: A0A0P0CKU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1736674:APS56 RS13310
gene id: 1736674:APS56_RS13310
uniprot id: A0A0P0D7F3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1736674:APS56 RS10425
gene id: 1736674:APS56_RS10425
uniprot id: A0A0P0D9J5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1736674:APS56 RS10435
gene id: 1736674:APS56_RS10435
uniprot id: A0A0P0D5V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1736674:APS56 RS12390
gene id: 1736674:APS56_RS12390
uniprot id: A0A0P0CI80
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1736674:APS56 RS00670
gene id: 1736674:APS56_RS00670
uniprot id: A0A0P0D1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS13755
gene id: 1736674:APS56_RS13755
uniprot id: A0A0P0DB36
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1736674:APS56 RS14140
gene id: 1736674:APS56_RS14140
uniprot id: A0A0P0CTK9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS04150
gene id: 1736674:APS56_RS04150
uniprot id: A0A0P0D374
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1736674:APS56 RS12935
gene id: 1736674:APS56_RS12935
uniprot id: A0A0P0DCU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1736674:APS56 RS13985
gene id: 1736674:APS56_RS13985
uniprot id: A0A0P0DB77
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1736674:APS56 RS08870
gene id: 1736674:APS56_RS08870
uniprot id: A0A0P0DBC5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1736674:APS56 RS04910
gene id: 1736674:APS56_RS04910
uniprot id: A0A0P0CEV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1736674:APS56 RS14555
gene id: 1736674:APS56_RS14555
uniprot id: A0A0P0CJ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS09850
gene id: 1736674:APS56_RS09850
uniprot id: A0A0P0CXT1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS10780
gene id: 1736674:APS56_RS10780
uniprot id: A0A0P0CM88
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS08185
gene id: 1736674:APS56_RS08185
uniprot id: A0A0P0CG16
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1736674:APS56 RS04165
gene id: 1736674:APS56_RS04165
uniprot id: A0A0N7HY64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1736674:APS56 RS08830
gene id: 1736674:APS56_RS08830
uniprot id: A0A0P0CQX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1736674:APS56 RS11345
gene id: 1736674:APS56_RS11345
uniprot id: A0A0P0D6D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS14425
gene id: 1736674:APS56_RS14425
uniprot id: A0A0P0DDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1736674:APS56 RS08105
gene id: 1736674:APS56_RS08105
uniprot id: A0A0P0CG57
names: Similarity
messages: Belongs to the asparaginase 1 family.

1736674:APS56 RS15755
gene id: 1736674:APS56_RS15755
uniprot id: A0A0P0CUA9
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS14265
gene id: 1736674:APS56_RS14265
uniprot id: A0A0P0D5M1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

1736674:APS56 RS16080
gene id: 1736674:APS56_RS16080
uniprot id: A0A0P0D6K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1736674:APS56 RS04980
gene id: 1736674:APS56_RS04980
uniprot id: A0A0P0CVS6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1736674:APS56 RS16140
gene id: 1736674:APS56_RS16140
uniprot id: A0A0P0D6L8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1736674:APS56 RS00070
gene id: 1736674:APS56_RS00070
uniprot id: A0A0N7HXX1
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1736674:APS56 RS05070
gene id: 1736674:APS56_RS05070
uniprot id: A0A0P0D108
names: Similarity
messages: Belongs to the glutamine synthetase family.

1736674:APS56 RS12040
gene id: 1736674:APS56_RS12040
uniprot id: A0A0P0CHZ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1736674:APS56 RS03250
gene id: 1736674:APS56_RS03250
uniprot id: A0A0P0D6A1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1736674:APS56 RS11120
gene id: 1736674:APS56_RS11120
uniprot id: A0A0P0D3U6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1736674:APS56 RS13840
gene id: 1736674:APS56_RS13840
uniprot id: A0A0P0DDL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1736674:APS56 RS01745
gene id: 1736674:APS56_RS01745
uniprot id: A0A0N7HY10
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1736674:APS56 RS07830
gene id: 1736674:APS56_RS07830
uniprot id: A0A0P0D298
names: Similarity
messages: Belongs to the glycosyl hydrolase 100 family.

1736674:APS56 RS03195
gene id: 1736674:APS56_RS03195
uniprot id: A0A0P0DCM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS14010
gene id: 1736674:APS56_RS14010
uniprot id: A0A0P0DDQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1736674:APS56 RS10645
gene id: 1736674:APS56_RS10645
uniprot id: A0A0P0CY56
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1736674:APS56 RS01850
gene id: 1736674:APS56_RS01850
uniprot id: A0A0P0CDH6
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3'.
messages: Belongs to the DpnII type II restriction endonuclease family.

1736674:APS56 RS04400
gene id: 1736674:APS56_RS04400
uniprot id: A0A0P0CJ94
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS01215
gene id: 1736674:APS56_RS01215
uniprot id: A0A0P0D253
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1736674:APS56 RS00185
gene id: 1736674:APS56_RS00185
uniprot id: A0A0P0D1N4
names: Similarity
messages: Belongs to the UPF0173 family.

1736674:APS56 RS02295
gene id: 1736674:APS56_RS02295
uniprot id: A0A0P0CI63
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS12255
gene id: 1736674:APS56_RS12255
uniprot id: A0A0P0D6U3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS06290
gene id: 1736674:APS56_RS06290
uniprot id: A0A0P0D3V4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1736674:APS56 RS05765
gene id: 1736674:APS56_RS05765
uniprot id: A0A0P0CEW3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1736674:APS56 RS10805
gene id: 1736674:APS56_RS10805
uniprot id: A0A0N7HYL4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1736674:APS56 RS05390
gene id: 1736674:APS56_RS05390
uniprot id: A0A0N7HY92
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS11330
gene id: 1736674:APS56_RS11330
uniprot id: A0A0P0D3Z0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1736674:APS56 RS05870
gene id: 1736674:APS56_RS05870
uniprot id: A0A0P0D9S5
names: Similarity
messages: Belongs to the SCO1/2 family.

1736674:APS56 RS13980
gene id: 1736674:APS56_RS13980
uniprot id: A0A0P0CP15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1736674:APS56 RS05905
gene id: 1736674:APS56_RS05905
uniprot id: A0A0P0D1F6
names: Similarity
messages: Belongs to the UxaA family.

1736674:APS56 RS00285
gene id: 1736674:APS56_RS00285
uniprot id: A0A0N7HXX6
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS13140
gene id: 1736674:APS56_RS13140
uniprot id: A0A0P0CIJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS12635
gene id: 1736674:APS56_RS12635
uniprot id: A0A0P0DD31
names: Similarity
messages: Belongs to the UxaA family.

1736674:APS56 RS11655
gene id: 1736674:APS56_RS11655
uniprot id: A0A0P0D6I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1736674:APS56 RS07760
gene id: 1736674:APS56_RS07760
uniprot id: A0A0P0CQ79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1736674:APS56 RS15540
gene id: 1736674:APS56_RS15540
uniprot id: A0A0P0D8K7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1736674:APS56 RS00925
gene id: 1736674:APS56_RS00925
uniprot id: A0A0P0CD60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1736674:APS56 RS02465
gene id: 1736674:APS56_RS02465
uniprot id: A0A0P0CDI2
names: Similarity
messages: Belongs to the nitroreductase family.

1736674:APS56 RS10825
gene id: 1736674:APS56_RS10825
uniprot id: A0A0P0CRX0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1736674:APS56 RS16575
gene id: 1736674:APS56_RS16575
uniprot id: A0A0P0CQB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1736674:APS56 RS13365
gene id: 1736674:APS56_RS13365
uniprot id: A0A0P0D7F8
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS04040
gene id: 1736674:APS56_RS04040
uniprot id: A0A0P0CE48
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS05545
gene id: 1736674:APS56_RS05545
uniprot id: A0A0P0CF37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1736674:APS56 RS10135
gene id: 1736674:APS56_RS10135
uniprot id: A0A0P0CH29
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1736674:APS56 RS10855
gene id: 1736674:APS56_RS10855
uniprot id: A0A0P0DBW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1736674:APS56 RS11200
gene id: 1736674:APS56_RS11200
uniprot id: A0A0P0DFB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1736674:APS56 RS07370
gene id: 1736674:APS56_RS07370
uniprot id: A0A0P0DAQ1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1736674:APS56 RS09025
gene id: 1736674:APS56_RS09025
uniprot id: A0A0N7HYH3
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1736674:APS56 RS16520
gene id: 1736674:APS56_RS16520
uniprot id: A0A0P0CQA9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1736674:APS56 RS01950
gene id: 1736674:APS56_RS01950
uniprot id: A0A0N7HY15
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1736674:APS56 RS03275
gene id: 1736674:APS56_RS03275
uniprot id: A0A0P0D8Z7
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS09450
gene id: 1736674:APS56_RS09450
uniprot id: A0A0P0D330
names: Similarity
messages: Belongs to the P(II) protein family.

1736674:APS56 RS08885
gene id: 1736674:APS56_RS08885
uniprot id: A0A0P0CXE5
names: Similarity
messages: Belongs to the fabD family.

1736674:APS56 RS09455
gene id: 1736674:APS56_RS09455
uniprot id: A0A0P0CLM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS11155
gene id: 1736674:APS56_RS11155
uniprot id: A0A0P0CHJ8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1736674:APS56 RS09720
gene id: 1736674:APS56_RS09720
uniprot id: A0A0P0CRD4
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS05675
gene id: 1736674:APS56_RS05675
uniprot id: A0A0P0D3P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS05115
gene id: 1736674:APS56_RS05115
uniprot id: A0A0P0D9S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS05150
gene id: 1736674:APS56_RS05150
uniprot id: A0A0P0D766
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS08890
gene id: 1736674:APS56_RS08890
uniprot id: A0A0P0CQY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1736674:APS56 RS16315
gene id: 1736674:APS56_RS16315
uniprot id: A0A0P0CUI9
names: Similarity
messages: Belongs to the IMPACT family.

1736674:APS56 RS11250
gene id: 1736674:APS56_RS11250
uniprot id: A0A0P0D3X5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1736674:APS56 RS16515
gene id: 1736674:APS56_RS16515
uniprot id: A0A0P0D6S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1736674:APS56 RS16105
gene id: 1736674:APS56_RS16105
uniprot id: A0A0P0CK01
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1736674:APS56 RS11830
gene id: 1736674:APS56_RS11830
uniprot id: A0A0P0DA68
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1736674:APS56 RS14770
gene id: 1736674:APS56_RS14770
uniprot id: A0A0P0DBL9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1736674:APS56 RS09245
gene id: 1736674:APS56_RS09245
uniprot id: A0A0P0DBI7
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS02895
gene id: 1736674:APS56_RS02895
uniprot id: A0A0N7HY36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1736674:APS56 RS09590
gene id: 1736674:APS56_RS09590
uniprot id: A0A0P0D966
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS08585
gene id: 1736674:APS56_RS08585
uniprot id: A0A0P0CL77
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS07425
gene id: 1736674:APS56_RS07425
uniprot id: A0A0P0CFV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1736674:APS56 RS00570
gene id: 1736674:APS56_RS00570
uniprot id: A0A0N7HXY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1736674:APS56 RS12230
gene id: 1736674:APS56_RS12230
uniprot id: A0A0P0CZ05
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS08405
gene id: 1736674:APS56_RS08405
uniprot id: A0A0P0D8P1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1736674:APS56 RS12785
gene id: 1736674:APS56_RS12785
uniprot id: A0A0P0CNB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1736674:APS56 RS09690
gene id: 1736674:APS56_RS09690
uniprot id: A0A0P0CGR0
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1736674:APS56 RS13315
gene id: 1736674:APS56_RS13315
uniprot id: A0A0P0DD12
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1736674:APS56 RS10980
gene id: 1736674:APS56_RS10980
uniprot id: A0A0P0DCB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1736674:APS56 RS02125
gene id: 1736674:APS56_RS02125
uniprot id: A0A0P0CI32
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1736674:APS56 RS13025
gene id: 1736674:APS56_RS13025
uniprot id: A0A0N7HYR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

1736674:APS56 RS09865
gene id: 1736674:APS56_RS09865
uniprot id: A0A0P0CLT4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1736674:APS56 RS14250
gene id: 1736674:APS56_RS14250
uniprot id: A0A0P0CJ21
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1736674:APS56 RS10810
gene id: 1736674:APS56_RS10810
uniprot id: A0A0P0DC84
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1736674:APS56 RS03595
gene id: 1736674:APS56_RS03595
uniprot id: A0A0P0CE83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1736674:APS56 RS13070
gene id: 1736674:APS56_RS13070
uniprot id: A0A0P0CII9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1736674:APS56 RS15500
gene id: 1736674:APS56_RS15500
uniprot id: A0A0P0CJN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1736674:APS56 RS12200
gene id: 1736674:APS56_RS12200
uniprot id: A0A0P0DCI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1736674:APS56 RS09505
gene id: 1736674:APS56_RS09505
uniprot id: A0A0P0D340
names: Similarity
messages: Belongs to the aspartokinase family.

1736674:APS56 RS08215
gene id: 1736674:APS56_RS08215
uniprot id: A0A0P0D8L2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS00870
gene id: 1736674:APS56_RS00870
uniprot id: A0A0P0CCT4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1736674:APS56 RS09270
gene id: 1736674:APS56_RS09270
uniprot id: A0A0N7HYH9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1736674:APS56 RS10650
gene id: 1736674:APS56_RS10650
uniprot id: A0A0P0CRU1
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS12660
gene id: 1736674:APS56_RS12660
uniprot id: A0A0P0D4P4
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1736674:APS56 RS03080
gene id: 1736674:APS56_RS03080
uniprot id: A0A0N7HY40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1736674:APS56 RS08540
gene id: 1736674:APS56_RS08540
uniprot id: A0A0P0D4S6
names: Similarity
messages: Belongs to the peptidase C40 family.

1736674:APS56 RS08045
gene id: 1736674:APS56_RS08045
uniprot id: A0A0N7HYF1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1736674:APS56 RS07680
gene id: 1736674:APS56_RS07680
uniprot id: A0A0P0CFZ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1736674:APS56 RS03600
gene id: 1736674:APS56_RS03600
uniprot id: A0A0N7HZ06
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1736674:APS56 RS11080
gene id: 1736674:APS56_RS11080
uniprot id: A0A0P0D699
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

1736674:APS56 RS07905
gene id: 1736674:APS56_RS07905
uniprot id: A0A0N7HYE8
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1736674:APS56 RS09130
gene id: 1736674:APS56_RS09130
uniprot id: A0A0P0DBG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1736674:APS56 RS00450
gene id: 1736674:APS56_RS00450
uniprot id: A0A0N7HXY0
names: Similarity
messages: Belongs to the universal stress protein A family.

1736674:APS56 RS05825
gene id: 1736674:APS56_RS05825
uniprot id: A0A0P0DA30
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS04530
gene id: 1736674:APS56_RS04530
uniprot id: A0A0P0D986
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1736674:APS56 RS10500
gene id: 1736674:APS56_RS10500
uniprot id: A0A0P0CHA6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1736674:APS56 RS10295
gene id: 1736674:APS56_RS10295
uniprot id: A0A0P0CRN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1736674:APS56 RS08130
gene id: 1736674:APS56_RS08130
uniprot id: A0A0N7HYF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1736674:APS56 RS04970
gene id: 1736674:APS56_RS04970
uniprot id: A0A0P0D9Q2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1736674:APS56 RS10655
gene id: 1736674:APS56_RS10655
uniprot id: A0A0P0D3J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1736674:APS56 RS09565
gene id: 1736674:APS56_RS09565
uniprot id: A0A0P0CRB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1736674:APS56 RS08065
gene id: 1736674:APS56_RS08065
uniprot id: A0A0P0CX25
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1736674:APS56 RS14925
gene id: 1736674:APS56_RS14925
uniprot id: A0A0P0CTY1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1736674:APS56 RS14035
gene id: 1736674:APS56_RS14035
uniprot id: A0A0N7HYT9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1736674:APS56 RS08245
gene id: 1736674:APS56_RS08245
uniprot id: A0A0P0DB34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1736674:APS56 RS12885
gene id: 1736674:APS56_RS12885
uniprot id: A0A0P0CIG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1736674:APS56 RS16120
gene id: 1736674:APS56_RS16120
uniprot id: A0A0P0CVC1
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS11405
gene id: 1736674:APS56_RS11405
uniprot id: A0A0N7HYM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

1736674:APS56 RS09240
gene id: 1736674:APS56_RS09240
uniprot id: A0A0P0CGP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS12350
gene id: 1736674:APS56_RS12350
uniprot id: A0A0P0CSR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1736674:APS56 RS10565
gene id: 1736674:APS56_RS10565
uniprot id: A0A0P0DC35
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1736674:APS56 RS06575
gene id: 1736674:APS56_RS06575
uniprot id: A0A0P0CFH0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS01920
gene id: 1736674:APS56_RS01920
uniprot id: A0A0P0CDA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1736674:APS56 RS07405
gene id: 1736674:APS56_RS07405
uniprot id: A0A0P0D883
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1736674:APS56 RS01600
gene id: 1736674:APS56_RS01600
uniprot id: A0A0P0D802
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1736674:APS56 RS11950
gene id: 1736674:APS56_RS11950
uniprot id: A0A0P0DA81
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

1736674:APS56 RS14020
gene id: 1736674:APS56_RS14020
uniprot id: A0A0P0CZT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1736674:APS56 RS13115
gene id: 1736674:APS56_RS13115
uniprot id: A0A0P0DCX9
names: Similarity
messages: Belongs to the Skp family.

1736674:APS56 RS14105
gene id: 1736674:APS56_RS14105
uniprot id: A0A0P0D7U4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1736674:APS56 RS00270
gene id: 1736674:APS56_RS00270
uniprot id: A0A0P0CTP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1736674:APS56 RS13530
gene id: 1736674:APS56_RS13530
uniprot id: A0A0P0CTB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1736674:APS56 RS08525
gene id: 1736674:APS56_RS08525
uniprot id: A0A0P0CL71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1736674:APS56 RS07945
gene id: 1736674:APS56_RS07945
uniprot id: A0A0N7HYE9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1736674:APS56 RS12160
gene id: 1736674:APS56_RS12160
uniprot id: A0A0P0CI18
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS06310
gene id: 1736674:APS56_RS06310
uniprot id: A0A0N7HZ12
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1736674:APS56 RS04935
gene id: 1736674:APS56_RS04935
uniprot id: A0A0P0D0Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1736674:APS56 RS03055
gene id: 1736674:APS56_RS03055
uniprot id: A0A0P0D8L7
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1736674:APS56 RS08125
gene id: 1736674:APS56_RS08125
uniprot id: A0A0P0CX31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1736674:APS56 RS13860
gene id: 1736674:APS56_RS13860
uniprot id: A0A0P0D5G0
names: Similarity
messages: Belongs to the UPF0758 family.

1736674:APS56 RS07195
gene id: 1736674:APS56_RS07195
uniprot id: A0A0P0CFS2
names: Similarity
messages: Belongs to the arginase family.

1736674:APS56 RS12060
gene id: 1736674:APS56_RS12060
uniprot id: A0A0P0D4B8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1736674:APS56 RS04415
gene id: 1736674:APS56_RS04415
uniprot id: A0A0P0D967
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1736674:APS56 RS11445
gene id: 1736674:APS56_RS11445
uniprot id: A0A0N7HYM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS10505
gene id: 1736674:APS56_RS10505
uniprot id: A0A0P0DC28
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS08285
gene id: 1736674:APS56_RS08285
uniprot id: A0A0P0D4M1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1736674:APS56 RS15830
gene id: 1736674:APS56_RS15830
uniprot id: A0A0P0D6G4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1736674:APS56 RS02345
gene id: 1736674:APS56_RS02345
uniprot id: A0A0P0CUP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1736674:APS56 RS06195
gene id: 1736674:APS56_RS06195
uniprot id: A0A0P0CPE4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1736674:APS56 RS12225
gene id: 1736674:APS56_RS12225
uniprot id: A0A0P0CI30
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1736674:APS56 RS14945
gene id: 1736674:APS56_RS14945
uniprot id: A0A0P0D889
names: Similarity
messages: Belongs to the TrpC family.

1736674:APS56 RS11190
gene id: 1736674:APS56_RS11190
uniprot id: A0A0P0CMD9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1736674:APS56 RS00320
gene id: 1736674:APS56_RS00320
uniprot id: A0A0P0D7U1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1736674:APS56 RS07500
gene id: 1736674:APS56_RS07500
uniprot id: A0A0P0DAS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1736674:APS56 RS14145
gene id: 1736674:APS56_RS14145
uniprot id: A0A0N7HZ23
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1736674:APS56 RS15560
gene id: 1736674:APS56_RS15560
uniprot id: A0A0N7HYX4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS09410
gene id: 1736674:APS56_RS09410
uniprot id: A0A0P0D599
names: Similarity
messages: Belongs to the peptidase S41A family.

1736674:APS56 RS05080
gene id: 1736674:APS56_RS05080
uniprot id: A0A0P0D758
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS15265
gene id: 1736674:APS56_RS15265
uniprot id: A0A0P0CPN9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1736674:APS56 RS12775
gene id: 1736674:APS56_RS12775
uniprot id: A0A0P0CSZ0
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS10200
gene id: 1736674:APS56_RS10200
uniprot id: A0A0P0DBJ3
names: Similarity
messages: Belongs to the DtxR/MntR family.

1736674:APS56 RS05540
gene id: 1736674:APS56_RS05540
uniprot id: A0A0P0D9N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1736674:APS56 RS01445
gene id: 1736674:APS56_RS01445
uniprot id: A0A0P0CMA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1736674:APS56 RS03630
gene id: 1736674:APS56_RS03630
uniprot id: A0A0P0CIU8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1736674:APS56 RS02340
gene id: 1736674:APS56_RS02340
uniprot id: A0A0P0CKD7
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS13990
gene id: 1736674:APS56_RS13990
uniprot id: A0A0P0D7S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1736674:APS56 RS12370
gene id: 1736674:APS56_RS12370
uniprot id: A0A0P0D6W3
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS15195
gene id: 1736674:APS56_RS15195
uniprot id: A0A0N7HYW6
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS02310
gene id: 1736674:APS56_RS02310
uniprot id: A0A0P0D2L2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1736674:APS56 RS14655
gene id: 1736674:APS56_RS14655
uniprot id: A0A0P0D831
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1736674:APS56 RS09815
gene id: 1736674:APS56_RS09815
uniprot id: A0A0P0D5K2
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS12175
gene id: 1736674:APS56_RS12175
uniprot id: A0A0N7HYP6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1736674:APS56 RS07555
gene id: 1736674:APS56_RS07555
uniprot id: A0A0P0CFX6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS05375
gene id: 1736674:APS56_RS05375
uniprot id: A0A0P0D164
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1736674:APS56 RS14720
gene id: 1736674:APS56_RS14720
uniprot id: A0A0P0DDU8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1736674:APS56 RS15870
gene id: 1736674:APS56_RS15870
uniprot id: A0A0P0DFK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1736674:APS56 RS14680
gene id: 1736674:APS56_RS14680
uniprot id: A0A0P0CJC3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1736674:APS56 RS16385
gene id: 1736674:APS56_RS16385
uniprot id: A0A0P0D6Q8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS01845
gene id: 1736674:APS56_RS01845
uniprot id: A0A0P0D839
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1736674:APS56 RS09945
gene id: 1736674:APS56_RS09945
uniprot id: A0A0P0DBE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS08895
gene id: 1736674:APS56_RS08895
uniprot id: A0A0P0D2U3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1736674:APS56 RS08760
gene id: 1736674:APS56_RS08760
uniprot id: A0A0P0CXC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1736674:APS56 RS12595
gene id: 1736674:APS56_RS12595
uniprot id: A0A0N7HYQ6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1736674:APS56 RS14890
gene id: 1736674:APS56_RS14890
uniprot id: A0A0P0D876
names: Similarity
messages: Belongs to the DEAD box helicase family.

1736674:APS56 RS01770
gene id: 1736674:APS56_RS01770
uniprot id: A0A0P0D5N0
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1736674:APS56 RS07295
gene id: 1736674:APS56_RS07295
uniprot id: A0A0P0D478
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1736674:APS56 RS09495
gene id: 1736674:APS56_RS09495
uniprot id: A0A0P0CXP2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1736674:APS56 RS07850
gene id: 1736674:APS56_RS07850
uniprot id: A0A0P0DAH7
names: Similarity
messages: Belongs to the universal stress protein A family.

1736674:APS56 RS01110
gene id: 1736674:APS56_RS01110
uniprot id: A0A0P0CD78
names: Similarity
messages: Belongs to the peptidase M1 family.

1736674:APS56 RS07990
gene id: 1736674:APS56_RS07990
uniprot id: A0A0P0CFX7
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1736674:APS56 RS01425
gene id: 1736674:APS56_RS01425
uniprot id: A0A0P0D881
names: Similarity
messages: Belongs to the argonaute family. Long pAgo subfamily.

1736674:APS56 RS14495
gene id: 1736674:APS56_RS14495
uniprot id: A0A0N7HYV0
names: Similarity
messages: Belongs to the ParB family.

1736674:APS56 RS08535
gene id: 1736674:APS56_RS08535
uniprot id: A0A0P0D8R0
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1736674:APS56 RS14690
gene id: 1736674:APS56_RS14690
uniprot id: A0A0P0CTU8
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS15780
gene id: 1736674:APS56_RS15780
uniprot id: A0A0P0D8P6
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS09390
gene id: 1736674:APS56_RS09390
uniprot id: A0A0P0D321
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS13845
gene id: 1736674:APS56_RS13845
uniprot id: A0A0P0CIV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1736674:APS56 RS12850
gene id: 1736674:APS56_RS12850
uniprot id: A0A0N7HYR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS07360
gene id: 1736674:APS56_RS07360
uniprot id: A0A0P0DAB2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1736674:APS56 RS14390
gene id: 1736674:APS56_RS14390
uniprot id: A0A0P0CP69
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1736674:APS56 RS00785
gene id: 1736674:APS56_RS00785
uniprot id: A0A0P0D5B0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1736674:APS56 RS05780
gene id: 1736674:APS56_RS05780
uniprot id: A0A0P0CP94
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS07715
gene id: 1736674:APS56_RS07715
uniprot id: A0A0P0CKS0
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS00760
gene id: 1736674:APS56_RS00760
uniprot id: A0A0P0CTW8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1736674:APS56 RS02635
gene id: 1736674:APS56_RS02635
uniprot id: A0A0P0D6Y2
names: Similarity
messages: Belongs to the AHA1 family.

1736674:APS56 RS03020
gene id: 1736674:APS56_RS03020
uniprot id: A0A0P0CN16
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1736674:APS56 RS08900
gene id: 1736674:APS56_RS08900
uniprot id: A0A0P0CLB0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1736674:APS56 RS05535
gene id: 1736674:APS56_RS05535
uniprot id: A0A0P0D3N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1736674:APS56 RS01930
gene id: 1736674:APS56_RS01930
uniprot id: A0A0P0CMI7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1736674:APS56 RS01915
gene id: 1736674:APS56_RS01915
uniprot id: A0A0P0D8F4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1736674:APS56 RS03165
gene id: 1736674:APS56_RS03165
uniprot id: A0A0N7HY42
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1736674:APS56 RS02235
gene id: 1736674:APS56_RS02235
uniprot id: A0A0P0CI50
names: Similarity
messages: Belongs to the FemABX family.

1736674:APS56 RS03310
gene id: 1736674:APS56_RS03310
uniprot id: A0A0N7HY45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1736674:APS56 RS04655
gene id: 1736674:APS56_RS04655
uniprot id: A0A0P0D9A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS01905
gene id: 1736674:APS56_RS01905
uniprot id: A0A0P0CDI0
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1736674:APS56 RS10405
gene id: 1736674:APS56_RS10405
uniprot id: A0A0P0CY15
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1736674:APS56 RS06915
gene id: 1736674:APS56_RS06915
uniprot id: A0A0P0CPT5
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS14085
gene id: 1736674:APS56_RS14085
uniprot id: A0A0P0CTJ9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1736674:APS56 RS08725
gene id: 1736674:APS56_RS08725
uniprot id: A0A0P0D8T5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1736674:APS56 RS10000
gene id: 1736674:APS56_RS10000
uniprot id: A0A0P0D9C4
names: Similarity
messages: Belongs to the YicC/YloC family.

1736674:APS56 RS11970
gene id: 1736674:APS56_RS11970
uniprot id: A0A0P0CHZ7
names: Similarity
messages: Belongs to the peptidase S24 family.

1736674:APS56 RS05015
gene id: 1736674:APS56_RS05015
uniprot id: A0A0P0D9H4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS01480
gene id: 1736674:APS56_RS01480
uniprot id: A0A0P0CDC2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1736674:APS56 RS04475
gene id: 1736674:APS56_RS04475
uniprot id: A0A0N7HY71
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1736674:APS56 RS07875
gene id: 1736674:APS56_RS07875
uniprot id: A0A0P0CWZ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1736674:APS56 RS16395
gene id: 1736674:APS56_RS16395
uniprot id: A0A0P0DCD0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1736674:APS56 RS13535
gene id: 1736674:APS56_RS13535
uniprot id: A0A0P0D581
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS00475
gene id: 1736674:APS56_RS00475
uniprot id: A0A0P0D570
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS10680
gene id: 1736674:APS56_RS10680
uniprot id: A0A0N7HYL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1736674:APS56 RS05110
gene id: 1736674:APS56_RS05110
uniprot id: A0A0P0CEY2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1736674:APS56 RS02570
gene id: 1736674:APS56_RS02570
uniprot id: A0A0N7HY29
names: Similarity
messages: Belongs to the AHA1 family.

1736674:APS56 RS08170
gene id: 1736674:APS56_RS08170
uniprot id: A0A0P0DCU6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS08445
gene id: 1736674:APS56_RS08445
uniprot id: A0A0N7HYG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1736674:APS56 RS03715
gene id: 1736674:APS56_RS03715
uniprot id: A0A0P0CEA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1736674:APS56 RS13245
gene id: 1736674:APS56_RS13245
uniprot id: A0A0P0DD03
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1736674:APS56 RS14345
gene id: 1736674:APS56_RS14345
uniprot id: A0A0P0DDL3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1736674:APS56 RS11425
gene id: 1736674:APS56_RS11425
uniprot id: A0A0P0CHP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1736674:APS56 RS03855
gene id: 1736674:APS56_RS03855
uniprot id: A0A0P0CE18
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1736674:APS56 RS04395
gene id: 1736674:APS56_RS04395
uniprot id: A0A0N7HY69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1736674:APS56 RS02050
gene id: 1736674:APS56_RS02050
uniprot id: A0A0P0CKA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1736674:APS56 RS05050
gene id: 1736674:APS56_RS05050
uniprot id: A0A0P0CNY3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1736674:APS56 RS01945
gene id: 1736674:APS56_RS01945
uniprot id: A0A0P0D5Q6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1736674:APS56 RS02575
gene id: 1736674:APS56_RS02575
uniprot id: A0A0P0CI99
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS13890
gene id: 1736674:APS56_RS13890
uniprot id: A0A0P0CIW8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1736674:APS56 RS15895
gene id: 1736674:APS56_RS15895
uniprot id: A0A0P0CQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1736674:APS56 RS14170
gene id: 1736674:APS56_RS14170
uniprot id: A0A0P0D7V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1736674:APS56 RS01875
gene id: 1736674:APS56_RS01875
uniprot id: A0A0P0CMH9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1736674:APS56 RS11965
gene id: 1736674:APS56_RS11965
uniprot id: A0A0N7HYP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS15145
gene id: 1736674:APS56_RS15145
uniprot id: A0A0P0CPJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1736674:APS56 RS10870
gene id: 1736674:APS56_RS10870
uniprot id: A0A0P0CHE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1736674:APS56 RS15045
gene id: 1736674:APS56_RS15045
uniprot id: A0A0P0CJI0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1736674:APS56 RS10110
gene id: 1736674:APS56_RS10110
uniprot id: A0A0P0CLX4
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1736674:APS56 RS05925
gene id: 1736674:APS56_RS05925
uniprot id: A0A0P0D3S0
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1736674:APS56 RS16630
gene id: 1736674:APS56_RS16630
uniprot id: A0A0N7HYZ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1736674:APS56 RS14735
gene id: 1736674:APS56_RS14735
uniprot id: A0A0P0DE42
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS04140
gene id: 1736674:APS56_RS04140
uniprot id: A0A0P0CJ32
names: Similarity
messages: Belongs to the sterol desaturase family.

1736674:APS56 RS15340
gene id: 1736674:APS56_RS15340
uniprot id: A0A0P0D8H1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS07240
gene id: 1736674:APS56_RS07240
uniprot id: A0A0P0D472
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1736674:APS56 RS15005
gene id: 1736674:APS56_RS15005
uniprot id: A0A0P0DBR3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1736674:APS56 RS09375
gene id: 1736674:APS56_RS09375
uniprot id: A0A0P0CGL2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1736674:APS56 RS09540
gene id: 1736674:APS56_RS09540
uniprot id: A0A0P0CGT8
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1736674:APS56 RS02230
gene id: 1736674:APS56_RS02230
uniprot id: A0A0P0D079
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1736674:APS56 RS14850
gene id: 1736674:APS56_RS14850
uniprot id: A0A0P0DE73
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1736674:APS56 RS02965
gene id: 1736674:APS56_RS02965
uniprot id: A0A0P0CIE9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1736674:APS56 RS06325
gene id: 1736674:APS56_RS06325
uniprot id: A0A0P0CWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1736674:APS56 RS02300
gene id: 1736674:APS56_RS02300
uniprot id: A0A0P0DF39
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS00500
gene id: 1736674:APS56_RS00500
uniprot id: A0A0P0D7W6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1736674:APS56 RS03385
gene id: 1736674:APS56_RS03385
uniprot id: A0A0P0CKB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1736674:APS56 RS11910
gene id: 1736674:APS56_RS11910
uniprot id: A0A0P0DCQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1736674:APS56 RS08255
gene id: 1736674:APS56_RS08255
uniprot id: A0A0P0CX58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1736674:APS56 RS04425
gene id: 1736674:APS56_RS04425
uniprot id: A0A0P0D9G4
names: Similarity
messages: Belongs to the BshC family.

1736674:APS56 RS00695
gene id: 1736674:APS56_RS00695
uniprot id: A0A0P0CTV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS00345
gene id: 1736674:APS56_RS00345
uniprot id: A0A0P0CLV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1736674:APS56 RS04805
gene id: 1736674:APS56_RS04805
uniprot id: A0A0P0CVP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS13485
gene id: 1736674:APS56_RS13485
uniprot id: A0A0P0DAZ8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1736674:APS56 RS15405
gene id: 1736674:APS56_RS15405
uniprot id: A0A0P0DBX9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1736674:APS56 RS14435
gene id: 1736674:APS56_RS14435
uniprot id: A0A0P0D008
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1736674:APS56 RS06350
gene id: 1736674:APS56_RS06350
uniprot id: A0A0P0D7S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1736674:APS56 RS03585
gene id: 1736674:APS56_RS03585
uniprot id: A0A0P0D8U3
names: Similarity
messages: Belongs to the threonine synthase family.

1736674:APS56 RS05480
gene id: 1736674:APS56_RS05480
uniprot id: A0A0P0CF29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1736674:APS56 RS14285
gene id: 1736674:APS56_RS14285
uniprot id: A0A0P0D7X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1736674:APS56 RS10470
gene id: 1736674:APS56_RS10470
uniprot id: A0A0N7HYK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1736674:APS56 RS03770
gene id: 1736674:APS56_RS03770
uniprot id: A0A0P0D322
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1736674:APS56 RS16095
gene id: 1736674:APS56_RS16095
uniprot id: A0A0P0D8V2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1736674:APS56 RS00810
gene id: 1736674:APS56_RS00810
uniprot id: A0A0P0D804
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1736674:APS56 RS04310
gene id: 1736674:APS56_RS04310
uniprot id: A0A0N7HY67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1736674:APS56 RS14315
gene id: 1736674:APS56_RS14315
uniprot id: A0A0P0CTP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS08235
gene id: 1736674:APS56_RS08235
uniprot id: A0A0P0DAN7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1736674:APS56 RS12990
gene id: 1736674:APS56_RS12990
uniprot id: A0A0P0D765
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1736674:APS56 RS03615
gene id: 1736674:APS56_RS03615
uniprot id: A0A0P0CV56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1736674:APS56 RS10460
gene id: 1736674:APS56_RS10460
uniprot id: A0A0P0CY21
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1736674:APS56 RS12440
gene id: 1736674:APS56_RS12440
uniprot id: A0A0P0D6X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1736674:APS56 RS00595
gene id: 1736674:APS56_RS00595
uniprot id: A0A0P0CHH2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1736674:APS56 RS07815
gene id: 1736674:APS56_RS07815
uniprot id: A0A0P0CWY3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1736674:APS56 RS15765
gene id: 1736674:APS56_RS15765
uniprot id: A0A0N7HYX9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS13235
gene id: 1736674:APS56_RS13235
uniprot id: A0A0P0DAW1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1736674:APS56 RS07270
gene id: 1736674:APS56_RS07270
uniprot id: A0A0N7HYD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1736674:APS56 RS11055
gene id: 1736674:APS56_RS11055
uniprot id: A0A0P0CYD0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1736674:APS56 RS11245
gene id: 1736674:APS56_RS11245
uniprot id: A0A0P0CS69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1736674:APS56 RS14515
gene id: 1736674:APS56_RS14515
uniprot id: A0A0P0CP87
names: Subcellular Location Annotation
messages: Cytoplasm

1736674:APS56 RS11460
gene id: 1736674:APS56_RS11460
uniprot id: A0A0P0D1F3
names: Similarity
messages: Belongs to the YciI family.

1736674:APS56 RS08145
gene id: 1736674:APS56_RS08145
uniprot id: A0A0P0CL12
names: Similarity
messages: Belongs to the sigma-54 factor family.

1736674:APS56 RS13065
gene id: 1736674:APS56_RS13065
uniprot id: A0A0N7HYR7
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS03530
gene id: 1736674:APS56_RS03530
uniprot id: A0A0P0D8T1
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1736674:APS56 RS12530
gene id: 1736674:APS56_RS12530
uniprot id: A0A0P0CZ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1736674:APS56 RS10510
gene id: 1736674:APS56_RS10510
uniprot id: A0A0N7HYK7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1736674:APS56 RS10670
gene id: 1736674:APS56_RS10670
uniprot id: A0A0P0D615
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1736674:APS56 RS07600
gene id: 1736674:APS56_RS07600
uniprot id: A0A0P0D8A7
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1736674:APS56 RS10070
gene id: 1736674:APS56_RS10070
uniprot id: A0A0P0DBH0
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1736674:APS56 RS05225
gene id: 1736674:APS56_RS05225
uniprot id: A0A0P0D9J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1736674:APS56 RS06570
gene id: 1736674:APS56_RS06570
uniprot id: A0A0P0DA17
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1736674:APS56 RS05625
gene id: 1736674:APS56_RS05625
uniprot id: A0A0P0CF47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS08750
gene id: 1736674:APS56_RS08750
uniprot id: A0A0N7HYG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1736674:APS56 RS13735
gene id: 1736674:APS56_RS13735
uniprot id: A0A0P0CTE2
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS10600
gene id: 1736674:APS56_RS10600
uniprot id: A0A0N7HYK9
names: Similarity
messages: Belongs to the DprA/Smf family.

1736674:APS56 RS04815
gene id: 1736674:APS56_RS04815
uniprot id: A0A0P0D0W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1736674:APS56 RS06525
gene id: 1736674:APS56_RS06525
uniprot id: A0A0P0CWC5
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS07925
gene id: 1736674:APS56_RS07925
uniprot id: A0A0P0CFW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1736674:APS56 RS10445
gene id: 1736674:APS56_RS10445
uniprot id: A0A0P0CH90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1736674:APS56 RS06835
gene id: 1736674:APS56_RS06835
uniprot id: A0A0N7HYC3
names: Similarity
messages: Belongs to the AHA1 family.

1736674:APS56 RS15490
gene id: 1736674:APS56_RS15490
uniprot id: A0A0P0CJP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS14910
gene id: 1736674:APS56_RS14910
uniprot id: A0A0P0CJF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1736674:APS56 RS03675
gene id: 1736674:APS56_RS03675
uniprot id: A0A0N7HY53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

1736674:APS56 RS04555
gene id: 1736674:APS56_RS04555
uniprot id: A0A0N7HY73
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS01610
gene id: 1736674:APS56_RS01610
uniprot id: A0A0P0D8B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1736674:APS56 RS07485
gene id: 1736674:APS56_RS07485
uniprot id: A0A0P0CKJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS05550
gene id: 1736674:APS56_RS05550
uniprot id: A0A0P0D9Z3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1736674:APS56 RS05930
gene id: 1736674:APS56_RS05930
uniprot id: A0A0P0D9S9
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1736674:APS56 RS08115
gene id: 1736674:APS56_RS08115
uniprot id: A0A0P0DB17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1736674:APS56 RS09460
gene id: 1736674:APS56_RS09460
uniprot id: A0A0P0D943
names: Similarity
messages: Belongs to the P(II) protein family.

1736674:APS56 RS04650
gene id: 1736674:APS56_RS04650
uniprot id: A0A0P0D3E2
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS05560
gene id: 1736674:APS56_RS05560
uniprot id: A0A0P0CW09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1736674:APS56 RS14060
gene id: 1736674:APS56_RS14060
uniprot id: A0A0P0CJ16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1736674:APS56 RS16370
gene id: 1736674:APS56_RS16370
uniprot id: A0A0P0D0W5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1736674:APS56 RS00590
gene id: 1736674:APS56_RS00590
uniprot id: A0A0P0CZQ2
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS13210
gene id: 1736674:APS56_RS13210
uniprot id: A0A0P0CZG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1736674:APS56 RS04275
gene id: 1736674:APS56_RS04275
uniprot id: A0A0P0CJ68
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1736674:APS56 RS00480
gene id: 1736674:APS56_RS00480
uniprot id: A0A0P0D1S8
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1736674:APS56 RS02225
gene id: 1736674:APS56_RS02225
uniprot id: A0A0P0CMP3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1736674:APS56 RS14935
gene id: 1736674:APS56_RS14935
uniprot id: A0A0P0CPG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1736674:APS56 RS05630
gene id: 1736674:APS56_RS05630
uniprot id: A0A0P0D9Z9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1736674:APS56 RS08260
gene id: 1736674:APS56_RS08260
uniprot id: A0A0P0CQM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS03425
gene id: 1736674:APS56_RS03425
uniprot id: A0A0P0CDV9
names: Similarity
messages: Belongs to the nitroreductase family.

1736674:APS56 RS05530
gene id: 1736674:APS56_RS05530
uniprot id: A0A0N7HY95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1736674:APS56 RS08500
gene id: 1736674:APS56_RS08500
uniprot id: A0A0P0CG63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1736674:APS56 RS00175
gene id: 1736674:APS56_RS00175
uniprot id: A0A0P0CHB0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS05570
gene id: 1736674:APS56_RS05570
uniprot id: A0A0P0CP39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1736674:APS56 RS14070
gene id: 1736674:APS56_RS14070
uniprot id: A0A0P0CIZ9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1736674:APS56 RS04380
gene id: 1736674:APS56_RS04380
uniprot id: A0A0P0CQJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS02250
gene id: 1736674:APS56_RS02250
uniprot id: A0A0P0D2K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1736674:APS56 RS03545
gene id: 1736674:APS56_RS03545
uniprot id: A0A0P0CDX2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1736674:APS56 RS07800
gene id: 1736674:APS56_RS07800
uniprot id: A0A0P0CG07
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1736674:APS56 RS02010
gene id: 1736674:APS56_RS02010
uniprot id: A0A0P0D5R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1736674:APS56 RS08300
gene id: 1736674:APS56_RS08300
uniprot id: A0A0P0DB43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1736674:APS56 RS01830
gene id: 1736674:APS56_RS01830
uniprot id: A0A0N7HY12
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS14350
gene id: 1736674:APS56_RS14350
uniprot id: A0A0P0CJ65
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS07210
gene id: 1736674:APS56_RS07210
uniprot id: A0A0P0CWN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1736674:APS56 RS07300
gene id: 1736674:APS56_RS07300
uniprot id: A0A0P0DAA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1736674:APS56 RS11015
gene id: 1736674:APS56_RS11015
uniprot id: A0A0P0CMB9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1736674:APS56 RS10245
gene id: 1736674:APS56_RS10245
uniprot id: A0A0P0CLZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1736674:APS56 RS05035
gene id: 1736674:APS56_RS05035
uniprot id: A0A0P0CEI7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1736674:APS56 RS13435
gene id: 1736674:APS56_RS13435
uniprot id: A0A0P0D7G9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1736674:APS56 RS11230
gene id: 1736674:APS56_RS11230
uniprot id: A0A0P0DCF4
names: Similarity
messages: Belongs to the peptidase S9A family.

1736674:APS56 RS08475
gene id: 1736674:APS56_RS08475
uniprot id: A0A0P0D4R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS12055
gene id: 1736674:APS56_RS12055
uniprot id: A0A0P0CSK9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1736674:APS56 RS08840
gene id: 1736674:APS56_RS08840
uniprot id: A0A0N7HYG9
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1736674:APS56 RS10180
gene id: 1736674:APS56_RS10180
uniprot id: A0A0N7HYJ9
names: Similarity
messages: Belongs to the SCO1/2 family.

1736674:APS56 RS11420
gene id: 1736674:APS56_RS11420
uniprot id: A0A0P0DCH9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1736674:APS56 RS11720
gene id: 1736674:APS56_RS11720
uniprot id: A0A0P0DCB0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1736674:APS56 RS05000
gene id: 1736674:APS56_RS05000
uniprot id: A0A0P0CJI5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1736674:APS56 RS02840
gene id: 1736674:APS56_RS02840
uniprot id: A0A0N7HY35
names: Similarity
messages: Belongs to the pirin family.

1736674:APS56 RS04065
gene id: 1736674:APS56_RS04065
uniprot id: A0A0P0CJ26
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1736674:APS56 RS10065
gene id: 1736674:APS56_RS10065
uniprot id: A0A0P0D5Q3
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1736674:APS56 RS14125
gene id: 1736674:APS56_RS14125
uniprot id: A0A0P0DDR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1736674:APS56 RS03270
gene id: 1736674:APS56_RS03270
uniprot id: A0A0N7HY44
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1736674:APS56 RS08150
gene id: 1736674:APS56_RS08150
uniprot id: A0A0P0D8K2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1736674:APS56 RS03865
gene id: 1736674:APS56_RS03865
uniprot id: A0A0P0CND3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1736674:APS56 RS14835
gene id: 1736674:APS56_RS14835
uniprot id: A0A0N7HYV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1736674:APS56 RS12610
gene id: 1736674:APS56_RS12610
uniprot id: A0A0P0DAL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1736674:APS56 RS03465
gene id: 1736674:APS56_RS03465
uniprot id: A0A0P0D8S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1736674:APS56 RS04990
gene id: 1736674:APS56_RS04990
uniprot id: A0A0P0CNX6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS03190
gene id: 1736674:APS56_RS03190
uniprot id: A0A0P0D8Z1
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS04375
gene id: 1736674:APS56_RS04375
uniprot id: A0A0P0CVJ1
names: Similarity
messages: Belongs to the peptidase S8 family.

1736674:APS56 RS07320
gene id: 1736674:APS56_RS07320
uniprot id: A0A0P0CFL4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1736674:APS56 RS01980
gene id: 1736674:APS56_RS01980
uniprot id: A0A0P0CUJ4
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS06735
gene id: 1736674:APS56_RS06735
uniprot id: A0A0P0D406
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1736674:APS56 RS11340
gene id: 1736674:APS56_RS11340
uniprot id: A0A0P0D9W8
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS07375
gene id: 1736674:APS56_RS07375
uniprot id: A0A0P0CFM0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1736674:APS56 RS04520
gene id: 1736674:APS56_RS04520
uniprot id: A0A0P0D6V7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1736674:APS56 RS12490
gene id: 1736674:APS56_RS12490
uniprot id: A0A0P0CN32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1736674:APS56 RS05005
gene id: 1736674:APS56_RS05005
uniprot id: A0A0P0D741
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1736674:APS56 RS02400
gene id: 1736674:APS56_RS02400
uniprot id: A0A0P0D8M7
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS06560
gene id: 1736674:APS56_RS06560
uniprot id: A0A0P0D3Y5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS12875
gene id: 1736674:APS56_RS12875
uniprot id: A0A0P0CIF2
names: Similarity
messages: Belongs to the universal stress protein A family.

1736674:APS56 RS12485
gene id: 1736674:APS56_RS12485
uniprot id: A0A0P0D4K3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1736674:APS56 RS09480
gene id: 1736674:APS56_RS09480
uniprot id: A0A0N7HYI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1736674:APS56 RS16270
gene id: 1736674:APS56_RS16270
uniprot id: A0A0P0CQ84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS00415
gene id: 1736674:APS56_RS00415
uniprot id: A0A0P0CHE4
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS03040
gene id: 1736674:APS56_RS03040
uniprot id: A0A0P0CIF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1736674:APS56 RS02680
gene id: 1736674:APS56_RS02680
uniprot id: A0A0P0CUT6
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS14455
gene id: 1736674:APS56_RS14455
uniprot id: A0A0P0CQX5
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS00820
gene id: 1736674:APS56_RS00820
uniprot id: A0A0P0CTX6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS07675
gene id: 1736674:APS56_RS07675
uniprot id: A0A0P0DAF4
names: Similarity
messages: Belongs to the Dps family.

1736674:APS56 RS14275
gene id: 1736674:APS56_RS14275
uniprot id: A0A0P0DBD3
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

1736674:APS56 RS09335
gene id: 1736674:APS56_RS09335
uniprot id: A0A0P0CLJ5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS09075
gene id: 1736674:APS56_RS09075
uniprot id: A0A0P0DBF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1736674:APS56 RS08155
gene id: 1736674:APS56_RS08155
uniprot id: A0A0P0D4J9
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS05185
gene id: 1736674:APS56_RS05185
uniprot id: A0A0P0CVV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1736674:APS56 RS10350
gene id: 1736674:APS56_RS10350
uniprot id: A0A0N7HYK3
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1736674:APS56 RS11310
gene id: 1736674:APS56_RS11310
uniprot id: A0A0P0CS76
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1736674:APS56 RS12870
gene id: 1736674:APS56_RS12870
uniprot id: A0A0P0DCT8
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1736674:APS56 RS06400
gene id: 1736674:APS56_RS06400
uniprot id: A0A0P0CPH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1736674:APS56 RS03940
gene id: 1736674:APS56_RS03940
uniprot id: A0A0P0D6M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS15275
gene id: 1736674:APS56_RS15275
uniprot id: A0A0P0D8F9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1736674:APS56 RS10230
gene id: 1736674:APS56_RS10230
uniprot id: A0A0P0CXY8
names: Similarity
messages: Belongs to the UPF0102 family.

1736674:APS56 RS08205
gene id: 1736674:APS56_RS08205
uniprot id: A0A0P0D2F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1736674:APS56 RS06935
gene id: 1736674:APS56_RS06935
uniprot id: A0A0N7HYC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1736674:APS56 RS12110
gene id: 1736674:APS56_RS12110
uniprot id: A0A0P0CSM0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1736674:APS56 RS13965
gene id: 1736674:APS56_RS13965
uniprot id: A0A0P0CZS7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1736674:APS56 RS11180
gene id: 1736674:APS56_RS11180
uniprot id: A0A0P0CS59
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1736674:APS56 RS10730
gene id: 1736674:APS56_RS10730
uniprot id: A0A0P0D9N6
names: Similarity
messages: Belongs to the GARS family.

1736674:APS56 RS11760
gene id: 1736674:APS56_RS11760
uniprot id: A0A0P0D466
names: Similarity
messages: Belongs to the aspartokinase family.

1736674:APS56 RS07435
gene id: 1736674:APS56_RS07435
uniprot id: A0A0N7HYD7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1736674:APS56 RS07805
gene id: 1736674:APS56_RS07805
uniprot id: A0A0P0DAX1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1736674:APS56 RS14930
gene id: 1736674:APS56_RS14930
uniprot id: A0A0P0D5Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1736674:APS56 RS13695
gene id: 1736674:APS56_RS13695
uniprot id: A0A0P0DD93
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1736674:APS56 RS04740
gene id: 1736674:APS56_RS04740
uniprot id: A0A0P0CVN5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS15295
gene id: 1736674:APS56_RS15295
uniprot id: A0A0P0DEF4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1736674:APS56 RS10620
gene id: 1736674:APS56_RS10620
uniprot id: A0A0P0DBR4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1736674:APS56 RS15825
gene id: 1736674:APS56_RS15825
uniprot id: A0A0P0CUB9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1736674:APS56 RS00915
gene id: 1736674:APS56_RS00915
uniprot id: A0A0P0D7P5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.
messages: Membrane

1736674:APS56 RS13015
gene id: 1736674:APS56_RS13015
uniprot id: A0A0P0CZD6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1736674:APS56 RS07235
gene id: 1736674:APS56_RS07235
uniprot id: A0A0P0D864
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1736674:APS56 RS04180
gene id: 1736674:APS56_RS04180
uniprot id: A0A0P0CVF5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1736674:APS56 RS01095
gene id: 1736674:APS56_RS01095
uniprot id: A0A0N7HXZ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1736674:APS56 RS12150
gene id: 1736674:APS56_RS12150
uniprot id: A0A0P0CI25
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS04580
gene id: 1736674:APS56_RS04580
uniprot id: A0A0P0D3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS16415
gene id: 1736674:APS56_RS16415
uniprot id: A0A0P0CK53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1736674:APS56 RS07740
gene id: 1736674:APS56_RS07740
uniprot id: A0A0N7HYE4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS09015
gene id: 1736674:APS56_RS09015
uniprot id: A0A0P0CXG4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1736674:APS56 RS06590
gene id: 1736674:APS56_RS06590
uniprot id: A0A0P0CF91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1736674:APS56 RS14940
gene id: 1736674:APS56_RS14940
uniprot id: A0A0P0DBP7
names: Similarity
messages: Belongs to the TrpF family.

1736674:APS56 RS02455
gene id: 1736674:APS56_RS02455
uniprot id: A0A0P0D8N4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1736674:APS56 RS02785
gene id: 1736674:APS56_RS02785
uniprot id: A0A0N7HY34
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1736674:APS56 RS13040
gene id: 1736674:APS56_RS13040
uniprot id: A0A0P0DAT1
names: Similarity
messages: Belongs to the SCO1/2 family.

1736674:APS56 RS04250
gene id: 1736674:APS56_RS04250
uniprot id: A0A0P0CVH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1736674:APS56 RS08715
gene id: 1736674:APS56_RS08715
uniprot id: A0A0P0D2P8
names: Similarity
messages: Belongs to the universal stress protein A family.

1736674:APS56 RS09595
gene id: 1736674:APS56_RS09595
uniprot id: A0A0P0D5H5
names: Similarity
messages: Belongs to the ribF family.

1736674:APS56 RS02020
gene id: 1736674:APS56_RS02020
uniprot id: A0A0P0D865
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1736674:APS56 RS09635
gene id: 1736674:APS56_RS09635
uniprot id: A0A0P0CXQ9
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS04445
gene id: 1736674:APS56_RS04445
uniprot id: A0A0P0CNP8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1736674:APS56 RS15705
gene id: 1736674:APS56_RS15705
uniprot id: A0A0P0D6E1
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

1736674:APS56 RS03860
gene id: 1736674:APS56_RS03860
uniprot id: A0A0P0CVA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1736674:APS56 RS03765
gene id: 1736674:APS56_RS03765
uniprot id: A0A0N7HY55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS15820
gene id: 1736674:APS56_RS15820
uniprot id: A0A0P0D0N7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1736674:APS56 RS07530
gene id: 1736674:APS56_RS07530
uniprot id: A0A0P0CKP2
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS00165
gene id: 1736674:APS56_RS00165
uniprot id: A0A0P0CLT6
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS09290
gene id: 1736674:APS56_RS09290
uniprot id: A0A0P0D560
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS02075
gene id: 1736674:APS56_RS02075
uniprot id: A0A0P0D2I5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1736674:APS56 RS01495
gene id: 1736674:APS56_RS01495
uniprot id: A0A0P0CD35
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1736674:APS56 RS06550
gene id: 1736674:APS56_RS06550
uniprot id: A0A0P0D7V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1736674:APS56 RS03965
gene id: 1736674:APS56_RS03965
uniprot id: A0A0P0CE38
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1736674:APS56 RS09785
gene id: 1736674:APS56_RS09785
uniprot id: A0A0P0CXS2
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS04920
gene id: 1736674:APS56_RS04920
uniprot id: A0A0P0CEG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS14015
gene id: 1736674:APS56_RS14015
uniprot id: A0A0P0CIY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1736674:APS56 RS03920
gene id: 1736674:APS56_RS03920
uniprot id: A0A0P0CNE3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

1736674:APS56 RS07230
gene id: 1736674:APS56_RS07230
uniprot id: A0A0N7HYD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1736674:APS56 RS12075
gene id: 1736674:APS56_RS12075
uniprot id: A0A0P0D6R1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1736674:APS56 RS12420
gene id: 1736674:APS56_RS12420
uniprot id: A0A0P0D4J4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS12065
gene id: 1736674:APS56_RS12065
uniprot id: A0A0P0CMU8
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS08180
gene id: 1736674:APS56_RS08180
uniprot id: A0A0P0DB25
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1736674:APS56 RS00690
gene id: 1736674:APS56_RS00690
uniprot id: A0A0P0CCQ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1736674:APS56 RS10005
gene id: 1736674:APS56_RS10005
uniprot id: A0A0N7HYJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1736674:APS56 RS09465
gene id: 1736674:APS56_RS09465
uniprot id: A0A0P0D5B4
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1736674:APS56 RS14750
gene id: 1736674:APS56_RS14750
uniprot id: A0A0P0CTV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1736674:APS56 RS09220
gene id: 1736674:APS56_RS09220
uniprot id: A0A0P0D908
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1736674:APS56 RS16125
gene id: 1736674:APS56_RS16125
uniprot id: A0A0P0CK04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1736674:APS56 RS09380
gene id: 1736674:APS56_RS09380
uniprot id: A0A0P0CXM5
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1736674:APS56 RS05510
gene id: 1736674:APS56_RS05510
uniprot id: A0A0P0CP34
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1736674:APS56 RS11875
gene id: 1736674:APS56_RS11875
uniprot id: A0A0P0D483
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1736674:APS56 RS14175
gene id: 1736674:APS56_RS14175
uniprot id: A0A0P0DDI2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1736674:APS56 RS03280
gene id: 1736674:APS56_RS03280
uniprot id: A0A0P0CDU4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1736674:APS56 RS14985
gene id: 1736674:APS56_RS14985
uniprot id: A0A0P0CTY8
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1736674:APS56 RS08520
gene id: 1736674:APS56_RS08520
uniprot id: A0A0P0DFE4
names: Similarity
messages: Belongs to the peptidase S41A family.

1736674:APS56 RS01060
gene id: 1736674:APS56_RS01060
uniprot id: A0A0P0D833
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1736674:APS56 RS08950
gene id: 1736674:APS56_RS08950
uniprot id: A0A0P0D2V2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1736674:APS56 RS12975
gene id: 1736674:APS56_RS12975
uniprot id: A0A0P0CNE9
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1736674:APS56 RS11085
gene id: 1736674:APS56_RS11085
uniprot id: A0A0P0DC07
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1736674:APS56 RS01335
gene id: 1736674:APS56_RS01335
uniprot id: A0A0P0D5H9
names: Subcellular Location Annotation
messages: Cytoplasm

1736674:APS56 RS03580
gene id: 1736674:APS56_RS03580
uniprot id: A0A0P0D2Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS14480
gene id: 1736674:APS56_RS14480
uniprot id: A0A0P0CJ77
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1736674:APS56 RS02430
gene id: 1736674:APS56_RS02430
uniprot id: A0A0P0CI74
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1736674:APS56 RS15100
gene id: 1736674:APS56_RS15100
uniprot id: A0A0P0DE14
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Belongs to the gluconokinase GntK/GntV family.
messages: Homodimer.

1736674:APS56 RS04595
gene id: 1736674:APS56_RS04595
uniprot id: A0A0N7HY74
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS08480
gene id: 1736674:APS56_RS08480
uniprot id: A0A0P0DAS6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS13325
gene id: 1736674:APS56_RS13325
uniprot id: A0A0P0DDD5
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1736674:APS56 RS08775
gene id: 1736674:APS56_RS08775
uniprot id: A0A0P0D2R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1736674:APS56 RS11940
gene id: 1736674:APS56_RS11940
uniprot id: A0A0P0D491
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1736674:APS56 RS00390
gene id: 1736674:APS56_RS00390
uniprot id: A0A0P0CCK4
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS08495
gene id: 1736674:APS56_RS08495
uniprot id: A0A0P0DB66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1736674:APS56 RS06520
gene id: 1736674:APS56_RS06520
uniprot id: A0A0P0CF87
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1736674:APS56 RS13520
gene id: 1736674:APS56_RS13520
uniprot id: A0A0P0CIP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1736674:APS56 RS15420
gene id: 1736674:APS56_RS15420
uniprot id: A0A0P0DE72
names: Similarity
messages: Belongs to the DEAD box helicase family.

1736674:APS56 RS13030
gene id: 1736674:APS56_RS13030
uniprot id: A0A0P0D4Z2
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS13970
gene id: 1736674:APS56_RS13970
uniprot id: A0A0P0CTI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1736674:APS56 RS15125
gene id: 1736674:APS56_RS15125
uniprot id: A0A0P0DFJ5
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS08685
gene id: 1736674:APS56_RS08685
uniprot id: A0A0P0DB97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1736674:APS56 RS14000
gene id: 1736674:APS56_RS14000
uniprot id: A0A0P0DDF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1736674:APS56 RS01765
gene id: 1736674:APS56_RS01765
uniprot id: A0A0P0CHX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1736674:APS56 RS05615
gene id: 1736674:APS56_RS05615
uniprot id: A0A0P0D3N7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1736674:APS56 RS14725
gene id: 1736674:APS56_RS14725
uniprot id: A0A0P0CJA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1736674:APS56 RS07615
gene id: 1736674:APS56_RS07615
uniprot id: A0A0N7HYE1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1736674:APS56 RS10660
gene id: 1736674:APS56_RS10660
uniprot id: A0A0P0CM64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1736674:APS56 RS01995
gene id: 1736674:APS56_RS01995
uniprot id: A0A0N7HY16
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS06455
gene id: 1736674:APS56_RS06455
uniprot id: A0A0P0DFC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1736674:APS56 RS12020
gene id: 1736674:APS56_RS12020
uniprot id: A0A0P0D6P7
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1736674:APS56 RS06480
gene id: 1736674:APS56_RS06480
uniprot id: A0A0P0D1P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1736674:APS56 RS15485
gene id: 1736674:APS56_RS15485
uniprot id: A0A0P0DE80
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1736674:APS56 RS12035
gene id: 1736674:APS56_RS12035
uniprot id: A0A0P0DCS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS03005
gene id: 1736674:APS56_RS03005
uniprot id: A0A0P0D8V7
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS15215
gene id: 1736674:APS56_RS15215
uniprot id: A0A0P0DBU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

1736674:APS56 RS10285
gene id: 1736674:APS56_RS10285
uniprot id: A0A0P0CH22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1736674:APS56 RS14595
gene id: 1736674:APS56_RS14595
uniprot id: A0A0P0DBJ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS16135
gene id: 1736674:APS56_RS16135
uniprot id: A0A0P0CUG3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1736674:APS56 RS10900
gene id: 1736674:APS56_RS10900
uniprot id: A0A0P0D9Q6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1736674:APS56 RS03400
gene id: 1736674:APS56_RS03400
uniprot id: A0A0P0D8R2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1736674:APS56 RS05785
gene id: 1736674:APS56_RS05785
uniprot id: A0A0P0D1D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1736674:APS56 RS11620
gene id: 1736674:APS56_RS11620
uniprot id: A0A0P0CYN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1736674:APS56 RS07340
gene id: 1736674:APS56_RS07340
uniprot id: A0A0P0CKK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1736674:APS56 RS01130
gene id: 1736674:APS56_RS01130
uniprot id: A0A0P0CM62
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS16400
gene id: 1736674:APS56_RS16400
uniprot id: A0A0P0D905
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1736674:APS56 RS09650
gene id: 1736674:APS56_RS09650
uniprot id: A0A0P0CLP9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS00815
gene id: 1736674:APS56_RS00815
uniprot id: A0A0P0CCS0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1736674:APS56 RS01665
gene id: 1736674:APS56_RS01665
uniprot id: A0A0P0DCK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1736674:APS56 RS05600
gene id: 1736674:APS56_RS05600
uniprot id: A0A0P0D193
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1736674:APS56 RS05120
gene id: 1736674:APS56_RS05120
uniprot id: A0A0P0CEJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1736674:APS56 RS08765
gene id: 1736674:APS56_RS08765
uniprot id: A0A0N7HZ16
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1736674:APS56 RS01835
gene id: 1736674:APS56_RS01835
uniprot id: A0A0P0D5P4
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

1736674:APS56 RS11090
gene id: 1736674:APS56_RS11090
uniprot id: A0A0N7HYM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1736674:APS56 RS14040
gene id: 1736674:APS56_RS14040
uniprot id: A0A0P0CP23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1736674:APS56 RS13770
gene id: 1736674:APS56_RS13770
uniprot id: A0A0P0CIV7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1736674:APS56 RS11685
gene id: 1736674:APS56_RS11685
uniprot id: A0A0P0CYN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

1736674:APS56 RS11095
gene id: 1736674:APS56_RS11095
uniprot id: A0A0P0CHI6
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1736674:APS56 RS12580
gene id: 1736674:APS56_RS12580
uniprot id: A0A0P0CIB9
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS03095
gene id: 1736674:APS56_RS03095
uniprot id: A0A0P0D0F7
names: Subcellular Location Annotation
messages: Cytoplasm

1736674:APS56 RS03320
gene id: 1736674:APS56_RS03320
uniprot id: A0A0P0D8Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1736674:APS56 RS08755
gene id: 1736674:APS56_RS08755
uniprot id: A0A0P0CGA3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS00140
gene id: 1736674:APS56_RS00140
uniprot id: A0A0P0D7S1
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS13075
gene id: 1736674:APS56_RS13075
uniprot id: A0A0P0CQW4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1736674:APS56 RS06760
gene id: 1736674:APS56_RS06760
uniprot id: A0A0P0DAG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1736674:APS56 RS07665
gene id: 1736674:APS56_RS07665
uniprot id: A0A0P0D8C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS02360
gene id: 1736674:APS56_RS02360
uniprot id: A0A0P0CI69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1736674:APS56 RS13925
gene id: 1736674:APS56_RS13925
uniprot id: A0A0P0CP07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1736674:APS56 RS08165
gene id: 1736674:APS56_RS08165
uniprot id: A0A0P0CG69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1736674:APS56 RS11560
gene id: 1736674:APS56_RS11560
uniprot id: A0A0P0CYM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1736674:APS56 RS10080
gene id: 1736674:APS56_RS10080
uniprot id: A0A0P0DBV3
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS09205
gene id: 1736674:APS56_RS09205
uniprot id: A0A0P0CR42
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1736674:APS56 RS14320
gene id: 1736674:APS56_RS14320
uniprot id: A0A0N7HYU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1736674:APS56 RS01585
gene id: 1736674:APS56_RS01585
uniprot id: A0A0P0CHV7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1736674:APS56 RS09900
gene id: 1736674:APS56_RS09900
uniprot id: A0A0P0CGV0
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS00260
gene id: 1736674:APS56_RS00260
uniprot id: A0A0P0D7T2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1736674:APS56 RS03550
gene id: 1736674:APS56_RS03550
uniprot id: A0A0N7HY50
names: Similarity
messages: Belongs to the SUI1 family.

1736674:APS56 RS14830
gene id: 1736674:APS56_RS14830
uniprot id: A0A0P0D867
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS08905
gene id: 1736674:APS56_RS08905
uniprot id: A0A0P0D8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1736674:APS56 RS09675
gene id: 1736674:APS56_RS09675
uniprot id: A0A0P0CGV6
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS07765
gene id: 1736674:APS56_RS07765
uniprot id: A0A0P0D287
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1736674:APS56 RS03010
gene id: 1736674:APS56_RS03010
uniprot id: A0A0P0CDQ5
names: Similarity
messages: Belongs to the sulfatase family.

1736674:APS56 RS02135
gene id: 1736674:APS56_RS02135
uniprot id: A0A0P0D2J1
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS00225
gene id: 1736674:APS56_RS00225
uniprot id: A0A0P0CZK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1736674:APS56 RS14460
gene id: 1736674:APS56_RS14460
uniprot id: A0A0P0CP79
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS00610
gene id: 1736674:APS56_RS00610
uniprot id: A0A0P0D7K1
names: Similarity
messages: Belongs to the universal stress protein A family.

1736674:APS56 RS07620
gene id: 1736674:APS56_RS07620
uniprot id: A0A0P0CFY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1736674:APS56 RS12025
gene id: 1736674:APS56_RS12025
uniprot id: A0A0P0DCF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1736674:APS56 RS12155
gene id: 1736674:APS56_RS12155
uniprot id: A0A0P0DCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1736674:APS56 RS12475
gene id: 1736674:APS56_RS12475
uniprot id: A0A0N7HYQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1736674:APS56 RS11135
gene id: 1736674:APS56_RS11135
uniprot id: A0A0P0D9U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1736674:APS56 RS15355
gene id: 1736674:APS56_RS15355
uniprot id: A0A0P0CJM1
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1736674:APS56 RS13150
gene id: 1736674:APS56_RS13150
uniprot id: A0A0P0CT44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS13725
gene id: 1736674:APS56_RS13725
uniprot id: A0A0P0D1H0
names: Similarity
messages: Belongs to the SusD family.

1736674:APS56 RS02870
gene id: 1736674:APS56_RS02870
uniprot id: A0A0P0D8T6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1736674:APS56 RS12790
gene id: 1736674:APS56_RS12790
uniprot id: A0A0P0DAN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1736674:APS56 RS05175
gene id: 1736674:APS56_RS05175
uniprot id: A0A0N7HY87
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1736674:APS56 RS08545
gene id: 1736674:APS56_RS08545
uniprot id: A0A0P0DAT4
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS13405
gene id: 1736674:APS56_RS13405
uniprot id: A0A0P0CT88
names: Similarity
messages: Belongs to the NAD synthetase family.

1736674:APS56 RS14230
gene id: 1736674:APS56_RS14230
uniprot id: A0A0P0DDJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Heterotrimer of A, B and C subunits.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS04455
gene id: 1736674:APS56_RS04455
uniprot id: A0A0P0CJA3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1736674:APS56 RS10190
gene id: 1736674:APS56_RS10190
uniprot id: A0A0P0D9E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1736674:APS56 RS10960
gene id: 1736674:APS56_RS10960
uniprot id: A0A0P0D679
names: Subcellular Location Annotation
messages: Membrane

1736674:APS56 RS14255
gene id: 1736674:APS56_RS14255
uniprot id: A0A0P0CZX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1736674:APS56 RS10570
gene id: 1736674:APS56_RS10570
uniprot id: A0A0P0CH80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1736674:APS56 RS05400
gene id: 1736674:APS56_RS05400
uniprot id: A0A0P0D3M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1736674:APS56 RS00945
gene id: 1736674:APS56_RS00945
uniprot id: A0A0P0CM36
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1736674:APS56 RS14485
gene id: 1736674:APS56_RS14485
uniprot id: A0A0P0DDZ5
names: Similarity
messages: Belongs to the DapB family.

1736674:APS56 RS05555
gene id: 1736674:APS56_RS05555
uniprot id: A0A0P0CES7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1736674:APS56 RS15410
gene id: 1736674:APS56_RS15410
uniprot id: A0A0P0D8I5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1736674:APS56 RS11825
gene id: 1736674:APS56_RS11825
uniprot id: A0A0P0CMM1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1736674:APS56 RS07430
gene id: 1736674:APS56_RS07430
uniprot id: A0A0P0DAR2
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1736674:APS56 RS14055
gene id: 1736674:APS56_RS14055
uniprot id: A0A0P0DDG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1736674:APS56 RS12625
gene id: 1736674:APS56_RS12625
uniprot id: A0A0P0DCQ6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1736674:APS56 RS04545
gene id: 1736674:APS56_RS04545
uniprot id: A0A0P0CEB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1736674:APS56 RS05980
gene id: 1736674:APS56_RS05980
uniprot id: A0A0P0D7L3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1736674:APS56 RS06925
gene id: 1736674:APS56_RS06925
uniprot id: A0A0P0CKC6
names: Similarity
messages: Belongs to the AHA1 family.

1736674:APS56 RS11700
gene id: 1736674:APS56_RS11700
uniprot id: A0A0P0CMJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane