1727163:AO498 RS08815
gene id: 1727163:AO498_RS08815
uniprot id: A0A142EN12
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1727163:AO498 RS01465
gene id: 1727163:AO498_RS01465
uniprot id: A0A142EIT5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1727163:AO498 RS04180
gene id: 1727163:AO498_RS04180
uniprot id: A0A142EKD5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1727163:AO498 RS04225
gene id: 1727163:AO498_RS04225
uniprot id: A0A142EKE5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1727163:AO498 RS02205
gene id: 1727163:AO498_RS02205
uniprot id: A0A142EJ86
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS13400
gene id: 1727163:AO498_RS13400
uniprot id: A0A142EQN4
names: Similarity
messages: Belongs to the sulfatase family.

1727163:AO498 RS02190
gene id: 1727163:AO498_RS02190
uniprot id: A0A142EJ83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS06365
gene id: 1727163:AO498_RS06365
uniprot id: A0A142ELM4
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1727163:AO498 RS12455
gene id: 1727163:AO498_RS12455
uniprot id: A0A142EQ46
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS15250
gene id: 1727163:AO498_RS15250
uniprot id: A0A142ERQ6
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS11805
gene id: 1727163:AO498_RS11805
uniprot id: A0A142EPR9
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS10340
gene id: 1727163:AO498_RS10340
uniprot id: A0A142ENX3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1727163:AO498 RS03090
gene id: 1727163:AO498_RS03090
uniprot id: A0A142EJR2
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1727163:AO498 RS14660
gene id: 1727163:AO498_RS14660
uniprot id: A0A142ERD7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1727163:AO498 RS06085
gene id: 1727163:AO498_RS06085
uniprot id: A0A142ELG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1727163:AO498 RS01695
gene id: 1727163:AO498_RS01695
uniprot id: A0A142EIY1
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS04675
gene id: 1727163:AO498_RS04675
uniprot id: A0A142EKN4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS02055
gene id: 1727163:AO498_RS02055
uniprot id: A0A142EJ56
names: Subunit
messages: Monomer.

1727163:AO498 RS12945
gene id: 1727163:AO498_RS12945
uniprot id: A0A142EQE2
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1727163:AO498 RS02650
gene id: 1727163:AO498_RS02650
uniprot id: A0A142EJH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1727163:AO498 RS16895
gene id: 1727163:AO498_RS16895
uniprot id: A0A142ESM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1727163:AO498 RS08145
gene id: 1727163:AO498_RS08145
uniprot id: A0A142EMM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1727163:AO498 RS16415
gene id: 1727163:AO498_RS16415
uniprot id: A0A142ESD4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1727163:AO498 RS06005
gene id: 1727163:AO498_RS06005
uniprot id: A0A142ELF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1727163:AO498 RS05740
gene id: 1727163:AO498_RS05740
uniprot id: A0A142ELA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1727163:AO498 RS08200
gene id: 1727163:AO498_RS08200
uniprot id: A0A142EMN8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1727163:AO498 RS09030
gene id: 1727163:AO498_RS09030
uniprot id: A0A142EN55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1727163:AO498 RS07740
gene id: 1727163:AO498_RS07740
uniprot id: A0A142EME9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1727163:AO498 RS15035
gene id: 1727163:AO498_RS15035
uniprot id: A0A142ERL3
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1727163:AO498 RS07830
gene id: 1727163:AO498_RS07830
uniprot id: A0A142EMG7
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS04275
gene id: 1727163:AO498_RS04275
uniprot id: A0A142EKF5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1727163:AO498 RS08105
gene id: 1727163:AO498_RS08105
uniprot id: A0A142EML9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1727163:AO498 RS12940
gene id: 1727163:AO498_RS12940
uniprot id: A0A142EQE1
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS10925
gene id: 1727163:AO498_RS10925
uniprot id: A0A142EP89
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS00075
gene id: 1727163:AO498_RS00075
uniprot id: A0A142EI13
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1727163:AO498 RS06810
gene id: 1727163:AO498_RS06810
uniprot id: A0A142ELW3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1727163:AO498 RS01850
gene id: 1727163:AO498_RS01850
uniprot id: A0A142EJ13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS08605
gene id: 1727163:AO498_RS08605
uniprot id: A0A142EMW9
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1727163:AO498 RS06440
gene id: 1727163:AO498_RS06440
uniprot id: A0A142ELN9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS12800
gene id: 1727163:AO498_RS12800
uniprot id: A0A142EQB3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1727163:AO498 RS02655
gene id: 1727163:AO498_RS02655
uniprot id: A0A142EJH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS07930
gene id: 1727163:AO498_RS07930
uniprot id: A0A142EMI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS00100
gene id: 1727163:AO498_RS00100
uniprot id: A0A142EI18
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Belongs to the gluconokinase GntK/GntV family.
messages: Homodimer.

1727163:AO498 RS09850
gene id: 1727163:AO498_RS09850
uniprot id: A0A142ENM1
names: Similarity
messages: Belongs to the peptidase S13 family.

1727163:AO498 RS16345
gene id: 1727163:AO498_RS16345
uniprot id: A0A142ESC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1727163:AO498 RS13000
gene id: 1727163:AO498_RS13000
uniprot id: A0A142EQF3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1727163:AO498 RS04665
gene id: 1727163:AO498_RS04665
uniprot id: A0A142EKN2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1727163:AO498 RS05620
gene id: 1727163:AO498_RS05620
uniprot id: A0A142EL76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1727163:AO498 RS05660
gene id: 1727163:AO498_RS05660
uniprot id: A0A142EL84
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1727163:AO498 RS09860
gene id: 1727163:AO498_RS09860
uniprot id: A0A142ENM3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1727163:AO498 RS12265
gene id: 1727163:AO498_RS12265
uniprot id: A0A142EQ08
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1727163:AO498 RS02895
gene id: 1727163:AO498_RS02895
uniprot id: A0A142EJM3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1727163:AO498 RS05600
gene id: 1727163:AO498_RS05600
uniprot id: A0A142EL72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1727163:AO498 RS12950
gene id: 1727163:AO498_RS12950
uniprot id: A0A142EQE3
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS01375
gene id: 1727163:AO498_RS01375
uniprot id: A0A142EIR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1727163:AO498 RS12870
gene id: 1727163:AO498_RS12870
uniprot id: A0A142EQC7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1727163:AO498 RS09040
gene id: 1727163:AO498_RS09040
uniprot id: A0A142EN57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1727163:AO498 RS10330
gene id: 1727163:AO498_RS10330
uniprot id: A0A142ENX1
names: Similarity
messages: Belongs to the UxaA family.

1727163:AO498 RS06105
gene id: 1727163:AO498_RS06105
uniprot id: A0A142ELH3
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS05650
gene id: 1727163:AO498_RS05650
uniprot id: A0A142EL82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1727163:AO498 RS03070
gene id: 1727163:AO498_RS03070
uniprot id: A0A142EJQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1727163:AO498 RS04040
gene id: 1727163:AO498_RS04040
uniprot id: A0A142EKA7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1727163:AO498 RS06940
gene id: 1727163:AO498_RS06940
uniprot id: A0A142ELY9
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1727163:AO498 RS14900
gene id: 1727163:AO498_RS14900
uniprot id: A0A142ERI6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1727163:AO498 RS07695
gene id: 1727163:AO498_RS07695
uniprot id: A0A142EME0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1727163:AO498 RS16845
gene id: 1727163:AO498_RS16845
uniprot id: A0A142ESL5
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS00775
gene id: 1727163:AO498_RS00775
uniprot id: A0A142EIE9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1727163:AO498 RS09285
gene id: 1727163:AO498_RS09285
uniprot id: A0A142ENA6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1727163:AO498 RS07170
gene id: 1727163:AO498_RS07170
uniprot id: A0A142EM35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1727163:AO498 RS10310
gene id: 1727163:AO498_RS10310
uniprot id: A0A142ENW7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1727163:AO498 RS00660
gene id: 1727163:AO498_RS00660
uniprot id: A0A142EIC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1727163:AO498 RS05160
gene id: 1727163:AO498_RS05160
uniprot id: A0A142EKY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1727163:AO498 RS05775
gene id: 1727163:AO498_RS05775
uniprot id: A0A142ELA7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1727163:AO498 RS03680
gene id: 1727163:AO498_RS03680
uniprot id: A0A142EK34
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1727163:AO498 RS01030
gene id: 1727163:AO498_RS01030
uniprot id: A0A142EIJ8
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

1727163:AO498 RS05640
gene id: 1727163:AO498_RS05640
uniprot id: A0A142EL80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1727163:AO498 RS15700
gene id: 1727163:AO498_RS15700
uniprot id: A0A142ERZ4
names: Similarity
messages: Belongs to the DapA family.

1727163:AO498 RS02375
gene id: 1727163:AO498_RS02375
uniprot id: A0A142EJC0
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS00695
gene id: 1727163:AO498_RS00695
uniprot id: A0A142EID3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1727163:AO498 RS16530
gene id: 1727163:AO498_RS16530
uniprot id: A0A142ESF5
names: Similarity
messages: Belongs to the GroES chaperonin family.

1727163:AO498 RS07945
gene id: 1727163:AO498_RS07945
uniprot id: A0A142EMJ0
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS03320
gene id: 1727163:AO498_RS03320
uniprot id: A0A142EJV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1727163:AO498 RS14805
gene id: 1727163:AO498_RS14805
uniprot id: A0A142ERG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1727163:AO498 RS00965
gene id: 1727163:AO498_RS00965
uniprot id: A0A142EII6
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1727163:AO498 RS05970
gene id: 1727163:AO498_RS05970
uniprot id: A0A142ELE6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1727163:AO498 RS06145
gene id: 1727163:AO498_RS06145
uniprot id: A0A142ELI1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1727163:AO498 RS14415
gene id: 1727163:AO498_RS14415
uniprot id: A0A142ER88
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1727163:AO498 RS02085
gene id: 1727163:AO498_RS02085
uniprot id: A0A142EJ62
names: Similarity
messages: Belongs to the NDK family.

1727163:AO498 RS06375
gene id: 1727163:AO498_RS06375
uniprot id: A0A142ELM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1727163:AO498 RS11695
gene id: 1727163:AO498_RS11695
uniprot id: A0A142EPP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1727163:AO498 RS05635
gene id: 1727163:AO498_RS05635
uniprot id: A0A142EL79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1727163:AO498 RS12780
gene id: 1727163:AO498_RS12780
uniprot id: A0A142EQA9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1727163:AO498 RS01920
gene id: 1727163:AO498_RS01920
uniprot id: A0A142EJ28
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1727163:AO498 RS00720
gene id: 1727163:AO498_RS00720
uniprot id: A0A142EID8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1727163:AO498 RS00565
gene id: 1727163:AO498_RS00565
uniprot id: A0A142EIA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS02155
gene id: 1727163:AO498_RS02155
uniprot id: A0A142EJ76
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS15235
gene id: 1727163:AO498_RS15235
uniprot id: A0A142ERQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1727163:AO498 RS10515
gene id: 1727163:AO498_RS10515
uniprot id: A0A142EP06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1727163:AO498 RS00225
gene id: 1727163:AO498_RS00225
uniprot id: A0A142EI44
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS14065
gene id: 1727163:AO498_RS14065
uniprot id: A0A142ER17
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS05630
gene id: 1727163:AO498_RS05630
uniprot id: A0A142EL78
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1727163:AO498 RS09455
gene id: 1727163:AO498_RS09455
uniprot id: A0A142ENE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1727163:AO498 RS07795
gene id: 1727163:AO498_RS07795
uniprot id: A0A142EMG0
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS03865
gene id: 1727163:AO498_RS03865
uniprot id: A0A142EK71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1727163:AO498 RS12080
gene id: 1727163:AO498_RS12080
uniprot id: A0A142EPX2
names: Subcellular Location Annotation
messages: Secreted

1727163:AO498 RS15280
gene id: 1727163:AO498_RS15280
uniprot id: A0A142ERR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1727163:AO498 RS02380
gene id: 1727163:AO498_RS02380
uniprot id: A0A142EJC1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1727163:AO498 RS16860
gene id: 1727163:AO498_RS16860
uniprot id: A0A142ESL8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1727163:AO498 RS16755
gene id: 1727163:AO498_RS16755
uniprot id: A0A142ESJ7
names: Similarity
messages: Belongs to the sulfatase family.

1727163:AO498 RS15640
gene id: 1727163:AO498_RS15640
uniprot id: A0A142ERY2
names: Similarity
messages: Belongs to the sulfatase family.

1727163:AO498 RS15450
gene id: 1727163:AO498_RS15450
uniprot id: A0A142ERU4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1727163:AO498 RS07145
gene id: 1727163:AO498_RS07145
uniprot id: A0A142EM30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1727163:AO498 RS07525
gene id: 1727163:AO498_RS07525
uniprot id: A0A142EMA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1727163:AO498 RS03590
gene id: 1727163:AO498_RS03590
uniprot id: A0A142EK14
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1727163:AO498 RS05310
gene id: 1727163:AO498_RS05310
uniprot id: A0A142EL17
names: Similarity
messages: Belongs to the BshC family.

1727163:AO498 RS04030
gene id: 1727163:AO498_RS04030
uniprot id: A0A142EKA5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1727163:AO498 RS03060
gene id: 1727163:AO498_RS03060
uniprot id: A0A142EJQ6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1727163:AO498 RS13765
gene id: 1727163:AO498_RS13765
uniprot id: A0A142EQV7
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS12440
gene id: 1727163:AO498_RS12440
uniprot id: A0A142EQ43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1727163:AO498 RS06465
gene id: 1727163:AO498_RS06465
uniprot id: A0A142ELP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1727163:AO498 RS09945
gene id: 1727163:AO498_RS09945
uniprot id: A0A142ENP1
names: Similarity
messages: Belongs to the arginase family.

1727163:AO498 RS00955
gene id: 1727163:AO498_RS00955
uniprot id: A0A142EII4
names: Similarity
messages: Belongs to the threonine synthase family.

1727163:AO498 RS09460
gene id: 1727163:AO498_RS09460
uniprot id: A0A142ENE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1727163:AO498 RS09875
gene id: 1727163:AO498_RS09875
uniprot id: A0A142ENM6
names: Similarity
messages: Belongs to the YjdM family.

1727163:AO498 RS04800
gene id: 1727163:AO498_RS04800
uniprot id: A0A142EKQ9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS16805
gene id: 1727163:AO498_RS16805
uniprot id: A0A142ESK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1727163:AO498 RS15560
gene id: 1727163:AO498_RS15560
uniprot id: A0A142ERW6
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS02235
gene id: 1727163:AO498_RS02235
uniprot id: A0A142EJ92
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS03310
gene id: 1727163:AO498_RS03310
uniprot id: A0A142EJV7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1727163:AO498 RS05655
gene id: 1727163:AO498_RS05655
uniprot id: A0A142EL83
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1727163:AO498 RS00185
gene id: 1727163:AO498_RS00185
uniprot id: A0A142EI36
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1727163:AO498 RS06445
gene id: 1727163:AO498_RS06445
uniprot id: A0A142ELP0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1727163:AO498 RS16565
gene id: 1727163:AO498_RS16565
uniprot id: A0A142ESG2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1727163:AO498 RS00625
gene id: 1727163:AO498_RS00625
uniprot id: A0A142EIB9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1727163:AO498 RS14615
gene id: 1727163:AO498_RS14615
uniprot id: A0A142ERC8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1727163:AO498 RS12815
gene id: 1727163:AO498_RS12815
uniprot id: A0A142EQB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS08245
gene id: 1727163:AO498_RS08245
uniprot id: A0A142EMP7
names: Function
names: Similarity
messages: Belongs to the acyltransferase CrtO family.
messages: Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i.e. the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin. This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains.

1727163:AO498 RS01305
gene id: 1727163:AO498_RS01305
uniprot id: A0A142EIQ3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1727163:AO498 RS03160
gene id: 1727163:AO498_RS03160
uniprot id: A0A142EJS6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1727163:AO498 RS13855
gene id: 1727163:AO498_RS13855
uniprot id: A0A142EQX5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1727163:AO498 RS15735
gene id: 1727163:AO498_RS15735
uniprot id: A0A142ES01
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS04170
gene id: 1727163:AO498_RS04170
uniprot id: A0A142EKD3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1727163:AO498 RS06580
gene id: 1727163:AO498_RS06580
uniprot id: A0A142ELR7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1727163:AO498 RS13435
gene id: 1727163:AO498_RS13435
uniprot id: A0A142EQP1
names: Similarity
messages: Belongs to the peptidase S13 family.

1727163:AO498 RS09655
gene id: 1727163:AO498_RS09655
uniprot id: A0A142ENI1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1727163:AO498 RS05345
gene id: 1727163:AO498_RS05345
uniprot id: A0A142EL24
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1727163:AO498 RS09595
gene id: 1727163:AO498_RS09595
uniprot id: A0A142ENG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1727163:AO498 RS07725
gene id: 1727163:AO498_RS07725
uniprot id: A0A142EME6
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS06685
gene id: 1727163:AO498_RS06685
uniprot id: A0A142ELT8
names: Similarity
messages: Belongs to the peptidase S8 family.

1727163:AO498 RS03030
gene id: 1727163:AO498_RS03030
uniprot id: A0A142EJQ0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1727163:AO498 RS14385
gene id: 1727163:AO498_RS14385
uniprot id: A0A142ER82
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

1727163:AO498 RS08045
gene id: 1727163:AO498_RS08045
uniprot id: A0A142EMK6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1727163:AO498 RS11425
gene id: 1727163:AO498_RS11425
uniprot id: A0A142EPJ2
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS02045
gene id: 1727163:AO498_RS02045
uniprot id: A0A142EJ54
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1727163:AO498 RS12140
gene id: 1727163:AO498_RS12140
uniprot id: A0A142EPY3
names: Similarity
messages: Belongs to the DEAD box helicase family.

1727163:AO498 RS14495
gene id: 1727163:AO498_RS14495
uniprot id: A0A142ERA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1727163:AO498 RS13210
gene id: 1727163:AO498_RS13210
uniprot id: A0A142EQJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1727163:AO498 RS05860
gene id: 1727163:AO498_RS05860
uniprot id: A0A142ELC4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1727163:AO498 RS09675
gene id: 1727163:AO498_RS09675
uniprot id: A0A142ENI5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1727163:AO498 RS16000
gene id: 1727163:AO498_RS16000
uniprot id: A0A142ES53
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS16545
gene id: 1727163:AO498_RS16545
uniprot id: A0A142ESF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1727163:AO498 RS06885
gene id: 1727163:AO498_RS06885
uniprot id: A0A142ELX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Probably a homodimer.

1727163:AO498 RS02290
gene id: 1727163:AO498_RS02290
uniprot id: A0A142EJA3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1727163:AO498 RS00645
gene id: 1727163:AO498_RS00645
uniprot id: A0A142EIC3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1727163:AO498 RS00650
gene id: 1727163:AO498_RS00650
uniprot id: A0A142EIC4
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS13115
gene id: 1727163:AO498_RS13115
uniprot id: A0A142EQH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1727163:AO498 RS10695
gene id: 1727163:AO498_RS10695
uniprot id: A0A142EP42
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1727163:AO498 RS09855
gene id: 1727163:AO498_RS09855
uniprot id: A0A142ENM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1727163:AO498 RS12200
gene id: 1727163:AO498_RS12200
uniprot id: A0A142EPZ5
names: Similarity
messages: Belongs to the UPF0145 family.

1727163:AO498 RS09470
gene id: 1727163:AO498_RS09470
uniprot id: A0A142ENE4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1727163:AO498 RS16815
gene id: 1727163:AO498_RS16815
uniprot id: A0A142ESK9
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

1727163:AO498 RS10565
gene id: 1727163:AO498_RS10565
uniprot id: A0A142EP16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1727163:AO498 RS04995
gene id: 1727163:AO498_RS04995
uniprot id: A0A142EKV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1727163:AO498 RS03500
gene id: 1727163:AO498_RS03500
uniprot id: A0A142EJZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS13305
gene id: 1727163:AO498_RS13305
uniprot id: A0A142EQL4
names: Subcellular Location Annotation
messages: Nucleus

1727163:AO498 RS02320
gene id: 1727163:AO498_RS02320
uniprot id: A0A142EJA9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1727163:AO498 RS07410
gene id: 1727163:AO498_RS07410
uniprot id: A0A142EM84
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1727163:AO498 RS00275
gene id: 1727163:AO498_RS00275
uniprot id: A0A142EI54
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1727163:AO498 RS00735
gene id: 1727163:AO498_RS00735
uniprot id: A0A142EIE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS10270
gene id: 1727163:AO498_RS10270
uniprot id: A0A142ENV8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1727163:AO498 RS02745
gene id: 1727163:AO498_RS02745
uniprot id: A0A142EJJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1727163:AO498 RS08335
gene id: 1727163:AO498_RS08335
uniprot id: A0A142EMR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1727163:AO498 RS16410
gene id: 1727163:AO498_RS16410
uniprot id: A0A142ESD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1727163:AO498 RS01180
gene id: 1727163:AO498_RS01180
uniprot id: A0A142EIM8
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS09545
gene id: 1727163:AO498_RS09545
uniprot id: A0A142ENF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1727163:AO498 RS03720
gene id: 1727163:AO498_RS03720
uniprot id: A0A142EK42
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1727163:AO498 RS02550
gene id: 1727163:AO498_RS02550
uniprot id: A0A142EJF7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1727163:AO498 RS15785
gene id: 1727163:AO498_RS15785
uniprot id: A0A142ES11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS14930
gene id: 1727163:AO498_RS14930
uniprot id: A0A142ERJ2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1727163:AO498 RS14220
gene id: 1727163:AO498_RS14220
uniprot id: A0A142ER49
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1727163:AO498 RS03355
gene id: 1727163:AO498_RS03355
uniprot id: A0A142EJW6
names: Similarity
messages: Belongs to the RecJ family.

1727163:AO498 RS16740
gene id: 1727163:AO498_RS16740
uniprot id: A0A142ESJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1727163:AO498 RS01360
gene id: 1727163:AO498_RS01360
uniprot id: A0A142EIR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1727163:AO498 RS01660
gene id: 1727163:AO498_RS01660
uniprot id: A0A142EIX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1727163:AO498 RS10625
gene id: 1727163:AO498_RS10625
uniprot id: A0A142EP28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1727163:AO498 RS14175
gene id: 1727163:AO498_RS14175
uniprot id: A0A142ER39
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1727163:AO498 RS12180
gene id: 1727163:AO498_RS12180
uniprot id: A0A142EPZ1
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1727163:AO498 RS12425
gene id: 1727163:AO498_RS12425
uniprot id: A0A142EQ40
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1727163:AO498 RS00500
gene id: 1727163:AO498_RS00500
uniprot id: A0A142EI94
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1727163:AO498 RS04075
gene id: 1727163:AO498_RS04075
uniprot id: A0A142EKB4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS09235
gene id: 1727163:AO498_RS09235
uniprot id: A0A142EN96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1727163:AO498 RS04880
gene id: 1727163:AO498_RS04880
uniprot id: A0A142EKS5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1727163:AO498 RS12520
gene id: 1727163:AO498_RS12520
uniprot id: A0A142EQ59
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1727163:AO498 RS16490
gene id: 1727163:AO498_RS16490
uniprot id: A0A142ESE7
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS01710
gene id: 1727163:AO498_RS01710
uniprot id: A0A142EIY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1727163:AO498 RS15420
gene id: 1727163:AO498_RS15420
uniprot id: A0A142ERT9
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1727163:AO498 RS11680
gene id: 1727163:AO498_RS11680
uniprot id: A0A142EPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1727163:AO498 RS00525
gene id: 1727163:AO498_RS00525
uniprot id: A0A142EI99
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS11360
gene id: 1727163:AO498_RS11360
uniprot id: A0A142EPH9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1727163:AO498 RS11490
gene id: 1727163:AO498_RS11490
uniprot id: A0A142EPK5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1727163:AO498 RS08510
gene id: 1727163:AO498_RS08510
uniprot id: A0A142EMV1
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS09400
gene id: 1727163:AO498_RS09400
uniprot id: A0A142ENC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1727163:AO498 RS14685
gene id: 1727163:AO498_RS14685
uniprot id: A0A142ERE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1727163:AO498 RS14240
gene id: 1727163:AO498_RS14240
uniprot id: A0A142ER53
names: Similarity
messages: Belongs to the SufE family.

1727163:AO498 RS15350
gene id: 1727163:AO498_RS15350
uniprot id: A0A142ERS5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1727163:AO498 RS02685
gene id: 1727163:AO498_RS02685
uniprot id: A0A142EJI1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1727163:AO498 RS02220
gene id: 1727163:AO498_RS02220
uniprot id: A0A142EJ89
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1727163:AO498 RS16790
gene id: 1727163:AO498_RS16790
uniprot id: A0A142ESK4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS09690
gene id: 1727163:AO498_RS09690
uniprot id: A0A142ENI8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1727163:AO498 RS06535
gene id: 1727163:AO498_RS06535
uniprot id: A0A142ELQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1727163:AO498 RS05580
gene id: 1727163:AO498_RS05580
uniprot id: A0A142EL68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1727163:AO498 RS15195
gene id: 1727163:AO498_RS15195
uniprot id: A0A142ERP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1727163:AO498 RS09580
gene id: 1727163:AO498_RS09580
uniprot id: A0A142ENG6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1727163:AO498 RS04955
gene id: 1727163:AO498_RS04955
uniprot id: A0A142EKU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS13120
gene id: 1727163:AO498_RS13120
uniprot id: A0A142EQH7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1727163:AO498 RS10960
gene id: 1727163:AO498_RS10960
uniprot id: A0A142EP96
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS00725
gene id: 1727163:AO498_RS00725
uniprot id: A0A142EID9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1727163:AO498 RS16160
gene id: 1727163:AO498_RS16160
uniprot id: A0A142ES84
names: Similarity
messages: Belongs to the peptidase S49 family.

1727163:AO498 RS00915
gene id: 1727163:AO498_RS00915
uniprot id: A0A142EIH6
names: Similarity
messages: Belongs to the aspartokinase family.

1727163:AO498 RS06420
gene id: 1727163:AO498_RS06420
uniprot id: A0A142ELN5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1727163:AO498 RS02070
gene id: 1727163:AO498_RS02070
uniprot id: A0A142EJ59
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1727163:AO498 RS03140
gene id: 1727163:AO498_RS03140
uniprot id: A0A142EJS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1727163:AO498 RS09920
gene id: 1727163:AO498_RS09920
uniprot id: A0A142ENN6
names: Similarity
messages: Belongs to the SUI1 family.

1727163:AO498 RS01715
gene id: 1727163:AO498_RS01715
uniprot id: A0A142EIY5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1727163:AO498 RS03020
gene id: 1727163:AO498_RS03020
uniprot id: A0A142EJP8
names: Similarity
messages: Belongs to the peptidase S58 family.

1727163:AO498 RS09495
gene id: 1727163:AO498_RS09495
uniprot id: A0A142ENE9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1727163:AO498 RS09670
gene id: 1727163:AO498_RS09670
uniprot id: A0A142ENI4
names: Similarity
messages: Belongs to the DSD1 family.

1727163:AO498 RS00605
gene id: 1727163:AO498_RS00605
uniprot id: A0A142EIB5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1727163:AO498 RS05015
gene id: 1727163:AO498_RS05015
uniprot id: A0A142EKV4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1727163:AO498 RS05260
gene id: 1727163:AO498_RS05260
uniprot id: A0A142EL06
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1727163:AO498 RS16360
gene id: 1727163:AO498_RS16360
uniprot id: A0A142ESC3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1727163:AO498 RS01720
gene id: 1727163:AO498_RS01720
uniprot id: A0A142EIY6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS10700
gene id: 1727163:AO498_RS10700
uniprot id: A0A142EP43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1727163:AO498 RS07750
gene id: 1727163:AO498_RS07750
uniprot id: A0A142EMF1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1727163:AO498 RS04365
gene id: 1727163:AO498_RS04365
uniprot id: A0A142EKH2
names: Similarity
messages: Belongs to the DapA family.

1727163:AO498 RS05005
gene id: 1727163:AO498_RS05005
uniprot id: A0A142EKV2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1727163:AO498 RS05570
gene id: 1727163:AO498_RS05570
uniprot id: A0A142EL66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1727163:AO498 RS02600
gene id: 1727163:AO498_RS02600
uniprot id: A0A142EJG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1727163:AO498 RS08230
gene id: 1727163:AO498_RS08230
uniprot id: A0A142EMP4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1727163:AO498 RS06060
gene id: 1727163:AO498_RS06060
uniprot id: A0A142ELG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

1727163:AO498 RS10125
gene id: 1727163:AO498_RS10125
uniprot id: A0A142ENS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1727163:AO498 RS07790
gene id: 1727163:AO498_RS07790
uniprot id: A0A142EMF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1727163:AO498 RS03185
gene id: 1727163:AO498_RS03185
uniprot id: A0A142EJT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1727163:AO498 RS03600
gene id: 1727163:AO498_RS03600
uniprot id: A0A142EK16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1727163:AO498 RS04645
gene id: 1727163:AO498_RS04645
uniprot id: A0A142EKM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1727163:AO498 RS11280
gene id: 1727163:AO498_RS11280
uniprot id: A0A142EPG3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1727163:AO498 RS02350
gene id: 1727163:AO498_RS02350
uniprot id: A0A142EJB5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1727163:AO498 RS06475
gene id: 1727163:AO498_RS06475
uniprot id: A0A142ELP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1727163:AO498 RS02260
gene id: 1727163:AO498_RS02260
uniprot id: A0A142EJ97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1727163:AO498 RS10755
gene id: 1727163:AO498_RS10755
uniprot id: A0A142EP55
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1727163:AO498 RS12735
gene id: 1727163:AO498_RS12735
uniprot id: A0A142EQA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS05555
gene id: 1727163:AO498_RS05555
uniprot id: A0A142EL63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1727163:AO498 RS14505
gene id: 1727163:AO498_RS14505
uniprot id: A0A142ERA6
names: Similarity
messages: Belongs to the TrpF family.

1727163:AO498 RS12930
gene id: 1727163:AO498_RS12930
uniprot id: A0A142EQD9
names: Similarity
messages: Belongs to the FMO family.

1727163:AO498 RS08595
gene id: 1727163:AO498_RS08595
uniprot id: A0A142EMW7
names: Similarity
messages: Belongs to the thioredoxin family.

1727163:AO498 RS12920
gene id: 1727163:AO498_RS12920
uniprot id: A0A142EQD7
names: Similarity
messages: Belongs to the peptidase S8 family.

1727163:AO498 RS02695
gene id: 1727163:AO498_RS02695
uniprot id: A0A142EJI3
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1727163:AO498 RS06180
gene id: 1727163:AO498_RS06180
uniprot id: A0A142ELI8
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS05965
gene id: 1727163:AO498_RS05965
uniprot id: A0A142ELE5
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1727163:AO498 RS08660
gene id: 1727163:AO498_RS08660
uniprot id: A0A142EMY1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1727163:AO498 RS06510
gene id: 1727163:AO498_RS06510
uniprot id: A0A142ELQ4
names: Similarity
messages: Belongs to the creatininase superfamily.

1727163:AO498 RS02865
gene id: 1727163:AO498_RS02865
uniprot id: A0A142EJL7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS09935
gene id: 1727163:AO498_RS09935
uniprot id: A0A142ENN9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1727163:AO498 RS07340
gene id: 1727163:AO498_RS07340
uniprot id: A0A142EM70
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1727163:AO498 RS04255
gene id: 1727163:AO498_RS04255
uniprot id: A0A142EKF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1727163:AO498 RS11750
gene id: 1727163:AO498_RS11750
uniprot id: A0A142EPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1727163:AO498 RS04480
gene id: 1727163:AO498_RS04480
uniprot id: A0A142EKJ5
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS11590
gene id: 1727163:AO498_RS11590
uniprot id: A0A142EPM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1727163:AO498 RS06305
gene id: 1727163:AO498_RS06305
uniprot id: A0A142ELL2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1727163:AO498 RS03550
gene id: 1727163:AO498_RS03550
uniprot id: A0A142EK06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1727163:AO498 RS02395
gene id: 1727163:AO498_RS02395
uniprot id: A0A142EJC4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1727163:AO498 RS14715
gene id: 1727163:AO498_RS14715
uniprot id: A0A142ERE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1727163:AO498 RS01515
gene id: 1727163:AO498_RS01515
uniprot id: A0A142EIU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1727163:AO498 RS01240
gene id: 1727163:AO498_RS01240
uniprot id: A0A142EIP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1727163:AO498 RS10495
gene id: 1727163:AO498_RS10495
uniprot id: A0A142EP02
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1727163:AO498 RS09430
gene id: 1727163:AO498_RS09430
uniprot id: A0A142END5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1727163:AO498 RS05505
gene id: 1727163:AO498_RS05505
uniprot id: A0A142EL52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1727163:AO498 RS05465
gene id: 1727163:AO498_RS05465
uniprot id: A0A142EL44
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1727163:AO498 RS05565
gene id: 1727163:AO498_RS05565
uniprot id: A0A142EL65
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1727163:AO498 RS01175
gene id: 1727163:AO498_RS01175
uniprot id: A0A142EIM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1727163:AO498 RS07990
gene id: 1727163:AO498_RS07990
uniprot id: A0A142EMJ8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1727163:AO498 RS02805
gene id: 1727163:AO498_RS02805
uniprot id: A0A142EJK5
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1727163:AO498 RS09375
gene id: 1727163:AO498_RS09375
uniprot id: A0A142ENC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1727163:AO498 RS07330
gene id: 1727163:AO498_RS07330
uniprot id: A0A142EM68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1727163:AO498 RS07475
gene id: 1727163:AO498_RS07475
uniprot id: A0A142EM97
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1727163:AO498 RS10865
gene id: 1727163:AO498_RS10865
uniprot id: A0A142EP77
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1727163:AO498 RS11955
gene id: 1727163:AO498_RS11955
uniprot id: A0A142EPU7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS11875
gene id: 1727163:AO498_RS11875
uniprot id: A0A142EPT2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1727163:AO498 RS00920
gene id: 1727163:AO498_RS00920
uniprot id: A0A142EIH7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1727163:AO498 RS07965
gene id: 1727163:AO498_RS07965
uniprot id: A0A142EMJ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS12275
gene id: 1727163:AO498_RS12275
uniprot id: A0A142EQ10
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1727163:AO498 RS08805
gene id: 1727163:AO498_RS08805
uniprot id: A0A142EN10
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS06275
gene id: 1727163:AO498_RS06275
uniprot id: A0A142ELK6
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS09780
gene id: 1727163:AO498_RS09780
uniprot id: A0A142ENK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1727163:AO498 RS02210
gene id: 1727163:AO498_RS02210
uniprot id: A0A142EJ87
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1727163:AO498 RS15655
gene id: 1727163:AO498_RS15655
uniprot id: A0A142ERY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS01490
gene id: 1727163:AO498_RS01490
uniprot id: A0A142EIU0
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS07845
gene id: 1727163:AO498_RS07845
uniprot id: A0A142EMH0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1727163:AO498 RS14145
gene id: 1727163:AO498_RS14145
uniprot id: A0A142ER33
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS05585
gene id: 1727163:AO498_RS05585
uniprot id: A0A142EL69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1727163:AO498 RS10040
gene id: 1727163:AO498_RS10040
uniprot id: A0A142ENR1
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

1727163:AO498 RS09290
gene id: 1727163:AO498_RS09290
uniprot id: A0A142ENA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1727163:AO498 RS07985
gene id: 1727163:AO498_RS07985
uniprot id: A0A142EMJ7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1727163:AO498 RS12985
gene id: 1727163:AO498_RS12985
uniprot id: A0A142EQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1727163:AO498 RS12005
gene id: 1727163:AO498_RS12005
uniprot id: A0A142EPV7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1727163:AO498 RS04220
gene id: 1727163:AO498_RS04220
uniprot id: A0A142EKE4
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS04460
gene id: 1727163:AO498_RS04460
uniprot id: A0A142EKJ2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1727163:AO498 RS07190
gene id: 1727163:AO498_RS07190
uniprot id: A0A142EM39
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1727163:AO498 RS08380
gene id: 1727163:AO498_RS08380
uniprot id: A0A142EMS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1727163:AO498 RS05230
gene id: 1727163:AO498_RS05230
uniprot id: A0A142EL00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1727163:AO498 RS09465
gene id: 1727163:AO498_RS09465
uniprot id: A0A142ENE3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1727163:AO498 RS13955
gene id: 1727163:AO498_RS13955
uniprot id: A0A142EQZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS13355
gene id: 1727163:AO498_RS13355
uniprot id: A0A142EQM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1727163:AO498 RS00370
gene id: 1727163:AO498_RS00370
uniprot id: A0A142EI72
names: Similarity
messages: Belongs to the peptidase S41A family.

1727163:AO498 RS09965
gene id: 1727163:AO498_RS09965
uniprot id: A0A142ENP5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1727163:AO498 RS04850
gene id: 1727163:AO498_RS04850
uniprot id: A0A142EKR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1727163:AO498 RS07110
gene id: 1727163:AO498_RS07110
uniprot id: A0A142EM23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1727163:AO498 RS02505
gene id: 1727163:AO498_RS02505
uniprot id: A0A142EJE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1727163:AO498 RS11990
gene id: 1727163:AO498_RS11990
uniprot id: A0A142EPV4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1727163:AO498 RS03905
gene id: 1727163:AO498_RS03905
uniprot id: A0A142EK79
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1727163:AO498 RS10990
gene id: 1727163:AO498_RS10990
uniprot id: A0A142EPA2
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1727163:AO498 RS11340
gene id: 1727163:AO498_RS11340
uniprot id: A0A142EPH4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS08920
gene id: 1727163:AO498_RS08920
uniprot id: A0A142EN33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1727163:AO498 RS12235
gene id: 1727163:AO498_RS12235
uniprot id: A0A142EQ02
names: Similarity
messages: Belongs to the peptidase M17 family.

1727163:AO498 RS14310
gene id: 1727163:AO498_RS14310
uniprot id: A0A142ER67
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1727163:AO498 RS14470
gene id: 1727163:AO498_RS14470
uniprot id: A0A142ER99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1727163:AO498 RS12720
gene id: 1727163:AO498_RS12720
uniprot id: A0A142EQ97
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1727163:AO498 RS10480
gene id: 1727163:AO498_RS10480
uniprot id: A0A142ENZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1727163:AO498 RS00815
gene id: 1727163:AO498_RS00815
uniprot id: A0A142EIF7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1727163:AO498 RS04820
gene id: 1727163:AO498_RS04820
uniprot id: A0A142EKR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1727163:AO498 RS01840
gene id: 1727163:AO498_RS01840
uniprot id: A0A142EJ11
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS03455
gene id: 1727163:AO498_RS03455
uniprot id: A0A142EJY7
names: Similarity
messages: Belongs to the AHA1 family.

1727163:AO498 RS07690
gene id: 1727163:AO498_RS07690
uniprot id: A0A142EMD9
names: Subcellular Location Annotation
messages: Cytoplasm

1727163:AO498 RS09985
gene id: 1727163:AO498_RS09985
uniprot id: A0A142ENP9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1727163:AO498 RS07880
gene id: 1727163:AO498_RS07880
uniprot id: A0A142EMH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1727163:AO498 RS12055
gene id: 1727163:AO498_RS12055
uniprot id: A0A142EPW7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1727163:AO498 RS01625
gene id: 1727163:AO498_RS01625
uniprot id: A0A142EIW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS16810
gene id: 1727163:AO498_RS16810
uniprot id: A0A142ESK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1727163:AO498 RS12310
gene id: 1727163:AO498_RS12310
uniprot id: A0A142EQ17
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS05540
gene id: 1727163:AO498_RS05540
uniprot id: A0A142EL60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1727163:AO498 RS14920
gene id: 1727163:AO498_RS14920
uniprot id: A0A142ERJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1727163:AO498 RS00070
gene id: 1727163:AO498_RS00070
uniprot id: A0A142EI12
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS06625
gene id: 1727163:AO498_RS06625
uniprot id: A0A142ELS6
names: Similarity
messages: Belongs to the DapB family.

1727163:AO498 RS04935
gene id: 1727163:AO498_RS04935
uniprot id: A0A142EKT8
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS00640
gene id: 1727163:AO498_RS00640
uniprot id: A0A142EIC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1727163:AO498 RS15015
gene id: 1727163:AO498_RS15015
uniprot id: A0A142ERK9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1727163:AO498 RS02455
gene id: 1727163:AO498_RS02455
uniprot id: A0A142EJD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

1727163:AO498 RS04505
gene id: 1727163:AO498_RS04505
uniprot id: A0A142EKK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1727163:AO498 RS01370
gene id: 1727163:AO498_RS01370
uniprot id: A0A142EIR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1727163:AO498 RS10360
gene id: 1727163:AO498_RS10360
uniprot id: A0A142ENX7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1727163:AO498 RS13250
gene id: 1727163:AO498_RS13250
uniprot id: A0A142EQK3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1727163:AO498 RS12640
gene id: 1727163:AO498_RS12640
uniprot id: A0A142EQ82
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1727163:AO498 RS14300
gene id: 1727163:AO498_RS14300
uniprot id: A0A142ER65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1727163:AO498 RS11895
gene id: 1727163:AO498_RS11895
uniprot id: A0A142EPT6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1727163:AO498 RS09010
gene id: 1727163:AO498_RS09010
uniprot id: A0A142EN51
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS00015
gene id: 1727163:AO498_RS00015
uniprot id: A0A142EI01
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1727163:AO498 RS03015
gene id: 1727163:AO498_RS03015
uniprot id: A0A142EJP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1727163:AO498 RS15310
gene id: 1727163:AO498_RS15310
uniprot id: A0A142ERR7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1727163:AO498 RS13200
gene id: 1727163:AO498_RS13200
uniprot id: A0A142EQJ3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1727163:AO498 RS14510
gene id: 1727163:AO498_RS14510
uniprot id: A0A142ERA7
names: Similarity
messages: Belongs to the TrpC family.

1727163:AO498 RS14340
gene id: 1727163:AO498_RS14340
uniprot id: A0A142ER73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1727163:AO498 RS12490
gene id: 1727163:AO498_RS12490
uniprot id: A0A142EQ53
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS01365
gene id: 1727163:AO498_RS01365
uniprot id: A0A142EIR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1727163:AO498 RS11375
gene id: 1727163:AO498_RS11375
uniprot id: A0A142EPI2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1727163:AO498 RS10265
gene id: 1727163:AO498_RS10265
uniprot id: A0A142ENV7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1727163:AO498 RS08715
gene id: 1727163:AO498_RS08715
uniprot id: A0A142EMZ2
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1727163:AO498 RS05280
gene id: 1727163:AO498_RS05280
uniprot id: A0A142EL10
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1727163:AO498 RS12370
gene id: 1727163:AO498_RS12370
uniprot id: A0A142EQ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1727163:AO498 RS02075
gene id: 1727163:AO498_RS02075
uniprot id: A0A142EJ60
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1727163:AO498 RS16570
gene id: 1727163:AO498_RS16570
uniprot id: A0A142ESG3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1727163:AO498 RS05475
gene id: 1727163:AO498_RS05475
uniprot id: A0A142EL46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1727163:AO498 RS00575
gene id: 1727163:AO498_RS00575
uniprot id: A0A142EIA9
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1727163:AO498 RS01790
gene id: 1727163:AO498_RS01790
uniprot id: A0A142EJ01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1727163:AO498 RS06720
gene id: 1727163:AO498_RS06720
uniprot id: A0A142ELU5
names: Similarity
messages: Belongs to the creatininase superfamily.

1727163:AO498 RS01495
gene id: 1727163:AO498_RS01495
uniprot id: A0A142EIU1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1727163:AO498 RS11705
gene id: 1727163:AO498_RS11705
uniprot id: A0A142EPP9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1727163:AO498 RS04155
gene id: 1727163:AO498_RS04155
uniprot id: A0A142EKD0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1727163:AO498 RS02365
gene id: 1727163:AO498_RS02365
uniprot id: A0A142EJB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1727163:AO498 RS10390
gene id: 1727163:AO498_RS10390
uniprot id: A0A142ENY3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1727163:AO498 RS03770
gene id: 1727163:AO498_RS03770
uniprot id: A0A142EK52
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1727163:AO498 RS10595
gene id: 1727163:AO498_RS10595
uniprot id: A0A142EP22
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1727163:AO498 RS09150
gene id: 1727163:AO498_RS09150
uniprot id: A0A142EN79
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1727163:AO498 RS11940
gene id: 1727163:AO498_RS11940
uniprot id: A0A142EPU4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1727163:AO498 RS09435
gene id: 1727163:AO498_RS09435
uniprot id: A0A142END6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1727163:AO498 RS12120
gene id: 1727163:AO498_RS12120
uniprot id: A0A142EPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1727163:AO498 RS02095
gene id: 1727163:AO498_RS02095
uniprot id: A0A142EJ64
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS07955
gene id: 1727163:AO498_RS07955
uniprot id: A0A142EMJ2
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1727163:AO498 RS05110
gene id: 1727163:AO498_RS05110
uniprot id: A0A142EKX3
names: Similarity
messages: Belongs to the sulfatase family.

1727163:AO498 RS01935
gene id: 1727163:AO498_RS01935
uniprot id: A0A142EJ31
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS11950
gene id: 1727163:AO498_RS11950
uniprot id: A0A142EPU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1727163:AO498 RS15260
gene id: 1727163:AO498_RS15260
uniprot id: A0A142ERQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1727163:AO498 RS16475
gene id: 1727163:AO498_RS16475
uniprot id: A0A142ESE4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1727163:AO498 RS08655
gene id: 1727163:AO498_RS08655
uniprot id: A0A142EMY0
names: Subcellular Location Annotation
messages: Cytoplasm

1727163:AO498 RS04700
gene id: 1727163:AO498_RS04700
uniprot id: A0A142EKN9
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1727163:AO498 RS13945
gene id: 1727163:AO498_RS13945
uniprot id: A0A142EQZ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1727163:AO498 RS16275
gene id: 1727163:AO498_RS16275
uniprot id: A0A142ESA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1727163:AO498 RS01680
gene id: 1727163:AO498_RS01680
uniprot id: A0A142EIX8
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1727163:AO498 RS15990
gene id: 1727163:AO498_RS15990
uniprot id: A0A142ES51
names: Similarity
messages: Belongs to the sigma-54 factor family.

1727163:AO498 RS15470
gene id: 1727163:AO498_RS15470
uniprot id: A0A142ERU8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1727163:AO498 RS01075
gene id: 1727163:AO498_RS01075
uniprot id: A0A142EIK7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1727163:AO498 RS05515
gene id: 1727163:AO498_RS05515
uniprot id: A0A142EL54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1727163:AO498 RS12525
gene id: 1727163:AO498_RS12525
uniprot id: A0A142EQ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1727163:AO498 RS12390
gene id: 1727163:AO498_RS12390
uniprot id: A0A142EQ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS11385
gene id: 1727163:AO498_RS11385
uniprot id: A0A142EPI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

1727163:AO498 RS09440
gene id: 1727163:AO498_RS09440
uniprot id: A0A142END7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1727163:AO498 RS04185
gene id: 1727163:AO498_RS04185
uniprot id: A0A142EKD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1727163:AO498 RS01270
gene id: 1727163:AO498_RS01270
uniprot id: A0A142EIP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1727163:AO498 RS03875
gene id: 1727163:AO498_RS03875
uniprot id: A0A142EK73
names: Similarity
messages: Belongs to the LOG family.

1727163:AO498 RS14480
gene id: 1727163:AO498_RS14480
uniprot id: A0A142ERA1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1727163:AO498 RS05220
gene id: 1727163:AO498_RS05220
uniprot id: A0A142EKZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

1727163:AO498 RS14610
gene id: 1727163:AO498_RS14610
uniprot id: A0A142ERC7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1727163:AO498 RS13885
gene id: 1727163:AO498_RS13885
uniprot id: A0A142EQY1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

1727163:AO498 RS04990
gene id: 1727163:AO498_RS04990
uniprot id: A0A142EKU9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1727163:AO498 RS10765
gene id: 1727163:AO498_RS10765
uniprot id: A0A142EP57
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1727163:AO498 RS05595
gene id: 1727163:AO498_RS05595
uniprot id: A0A142EL71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1727163:AO498 RS02740
gene id: 1727163:AO498_RS02740
uniprot id: A0A142EJJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1727163:AO498 RS11155
gene id: 1727163:AO498_RS11155
uniprot id: A0A142EPD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1727163:AO498 RS06900
gene id: 1727163:AO498_RS06900
uniprot id: A0A142ELY1
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS09570
gene id: 1727163:AO498_RS09570
uniprot id: A0A142ENG4
names: Similarity
messages: Belongs to the DtxR/MntR family.

1727163:AO498 RS15255
gene id: 1727163:AO498_RS15255
uniprot id: A0A142ERQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1727163:AO498 RS06785
gene id: 1727163:AO498_RS06785
uniprot id: A0A142ELV8
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1727163:AO498 RS11450
gene id: 1727163:AO498_RS11450
uniprot id: A0A142EPJ7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1727163:AO498 RS07635
gene id: 1727163:AO498_RS07635
uniprot id: A0A142EMC8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1727163:AO498 RS16435
gene id: 1727163:AO498_RS16435
uniprot id: A0A142ESD8
names: Similarity
messages: Belongs to the threonine aldolase family.

1727163:AO498 RS01820
gene id: 1727163:AO498_RS01820
uniprot id: A0A142EJ07
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1727163:AO498 RS11040
gene id: 1727163:AO498_RS11040
uniprot id: A0A142EPB2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1727163:AO498 RS02540
gene id: 1727163:AO498_RS02540
uniprot id: A0A142EJF5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

1727163:AO498 RS06840
gene id: 1727163:AO498_RS06840
uniprot id: A0A142ELW9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1727163:AO498 RS04405
gene id: 1727163:AO498_RS04405
uniprot id: A0A142EKI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1727163:AO498 RS07755
gene id: 1727163:AO498_RS07755
uniprot id: A0A142EMF2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1727163:AO498 RS15100
gene id: 1727163:AO498_RS15100
uniprot id: A0A142ERM6
names: Similarity
messages: Belongs to the sulfatase family.

1727163:AO498 RS00315
gene id: 1727163:AO498_RS00315
uniprot id: A0A142EI62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1727163:AO498 RS10575
gene id: 1727163:AO498_RS10575
uniprot id: A0A142EP18
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1727163:AO498 RS00405
gene id: 1727163:AO498_RS00405
uniprot id: A0A142EI79
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1727163:AO498 RS04215
gene id: 1727163:AO498_RS04215
uniprot id: A0A142EKE3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1727163:AO498 RS00150
gene id: 1727163:AO498_RS00150
uniprot id: A0A142EI28
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1727163:AO498 RS06290
gene id: 1727163:AO498_RS06290
uniprot id: A0A142ELK9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1727163:AO498 RS14640
gene id: 1727163:AO498_RS14640
uniprot id: A0A142ERD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1727163:AO498 RS14325
gene id: 1727163:AO498_RS14325
uniprot id: A0A142ER70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1727163:AO498 RS02100
gene id: 1727163:AO498_RS02100
uniprot id: A0A142EJ65
names: Similarity
messages: Belongs to the SusD family.

1727163:AO498 RS03250
gene id: 1727163:AO498_RS03250
uniprot id: A0A142EJU4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1727163:AO498 RS02305
gene id: 1727163:AO498_RS02305
uniprot id: A0A142EJA6
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

1727163:AO498 RS06345
gene id: 1727163:AO498_RS06345
uniprot id: A0A142ELM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1727163:AO498 RS03745
gene id: 1727163:AO498_RS03745
uniprot id: A0A142EK47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS07365
gene id: 1727163:AO498_RS07365
uniprot id: A0A142EM75
names: Similarity
messages: Belongs to the XseB family.

1727163:AO498 RS05035
gene id: 1727163:AO498_RS05035
uniprot id: A0A142EKV8
names: Similarity
messages: Belongs to the IlvD/Edd family.

1727163:AO498 RS15380
gene id: 1727163:AO498_RS15380
uniprot id: A0A142ERT1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1727163:AO498 RS08615
gene id: 1727163:AO498_RS08615
uniprot id: A0A142EMX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1727163:AO498 RS03835
gene id: 1727163:AO498_RS03835
uniprot id: A0A142EK65
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

1727163:AO498 RS01005
gene id: 1727163:AO498_RS01005
uniprot id: A0A142EIJ4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1727163:AO498 RS01085
gene id: 1727163:AO498_RS01085
uniprot id: A0A142EIK9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1727163:AO498 RS05170
gene id: 1727163:AO498_RS05170
uniprot id: A0A142EKY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1727163:AO498 RS11120
gene id: 1727163:AO498_RS11120
uniprot id: A0A142EPC8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1727163:AO498 RS05145
gene id: 1727163:AO498_RS05145
uniprot id: A0A142EKY0
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS12805
gene id: 1727163:AO498_RS12805
uniprot id: A0A142EQB4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1727163:AO498 RS03915
gene id: 1727163:AO498_RS03915
uniprot id: A0A142EK81
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS00675
gene id: 1727163:AO498_RS00675
uniprot id: A0A142EIC9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1727163:AO498 RS16075
gene id: 1727163:AO498_RS16075
uniprot id: A0A142ES67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1727163:AO498 RS04430
gene id: 1727163:AO498_RS04430
uniprot id: A0A142EKI6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS07770
gene id: 1727163:AO498_RS07770
uniprot id: A0A142EMF5
names: Similarity
messages: Belongs to the ComB family.

1727163:AO498 RS11915
gene id: 1727163:AO498_RS11915
uniprot id: A0A142EPU0
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS00670
gene id: 1727163:AO498_RS00670
uniprot id: A0A142EIC8
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1727163:AO498 RS12290
gene id: 1727163:AO498_RS12290
uniprot id: A0A142EQ13
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1727163:AO498 RS00215
gene id: 1727163:AO498_RS00215
uniprot id: A0A142EI42
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1727163:AO498 RS14760
gene id: 1727163:AO498_RS14760
uniprot id: A0A142ERF7
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS13525
gene id: 1727163:AO498_RS13525
uniprot id: A0A142EQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1727163:AO498 RS06855
gene id: 1727163:AO498_RS06855
uniprot id: A0A142ELX2
names: Similarity
messages: Belongs to the ArsC family.

1727163:AO498 RS03295
gene id: 1727163:AO498_RS03295
uniprot id: A0A142EJV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1727163:AO498 RS14195
gene id: 1727163:AO498_RS14195
uniprot id: A0A142ER43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1727163:AO498 RS05480
gene id: 1727163:AO498_RS05480
uniprot id: A0A142EL47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1727163:AO498 RS08240
gene id: 1727163:AO498_RS08240
uniprot id: A0A142EMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1727163:AO498 RS04230
gene id: 1727163:AO498_RS04230
uniprot id: A0A142EKE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1727163:AO498 RS05405
gene id: 1727163:AO498_RS05405
uniprot id: A0A142EL36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1727163:AO498 RS01045
gene id: 1727163:AO498_RS01045
uniprot id: A0A142EIK1
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS05025
gene id: 1727163:AO498_RS05025
uniprot id: A0A142EKV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS05350
gene id: 1727163:AO498_RS05350
uniprot id: A0A142EL25
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1727163:AO498 RS05835
gene id: 1727163:AO498_RS05835
uniprot id: A0A142ELB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1727163:AO498 RS03625
gene id: 1727163:AO498_RS03625
uniprot id: A0A142EK22
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1727163:AO498 RS02425
gene id: 1727163:AO498_RS02425
uniprot id: A0A142EJD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS04495
gene id: 1727163:AO498_RS04495
uniprot id: A0A142EKJ8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1727163:AO498 RS13510
gene id: 1727163:AO498_RS13510
uniprot id: A0A142EQQ5
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS16485
gene id: 1727163:AO498_RS16485
uniprot id: A0A142ESE6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS09880
gene id: 1727163:AO498_RS09880
uniprot id: A0A142ENM7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1727163:AO498 RS13350
gene id: 1727163:AO498_RS13350
uniprot id: A0A142EQM3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1727163:AO498 RS09020
gene id: 1727163:AO498_RS09020
uniprot id: A0A142EN53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS09015
gene id: 1727163:AO498_RS09015
uniprot id: A0A142EN52
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1727163:AO498 RS05060
gene id: 1727163:AO498_RS05060
uniprot id: A0A142EKW3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1727163:AO498 RS04265
gene id: 1727163:AO498_RS04265
uniprot id: A0A142EKF3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1727163:AO498 RS14750
gene id: 1727163:AO498_RS14750
uniprot id: A0A142ERF5
names: Similarity
messages: Belongs to the IMPACT family.

1727163:AO498 RS11945
gene id: 1727163:AO498_RS11945
uniprot id: A0A142EPU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1727163:AO498 RS07915
gene id: 1727163:AO498_RS07915
uniprot id: A0A142EMI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS05575
gene id: 1727163:AO498_RS05575
uniprot id: A0A142EL67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1727163:AO498 RS06325
gene id: 1727163:AO498_RS06325
uniprot id: A0A142ELL6
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS06615
gene id: 1727163:AO498_RS06615
uniprot id: A0A142ELS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1727163:AO498 RS16260
gene id: 1727163:AO498_RS16260
uniprot id: A0A142ESA4
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1727163:AO498 RS16010
gene id: 1727163:AO498_RS16010
uniprot id: A0A142ES55
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS01200
gene id: 1727163:AO498_RS01200
uniprot id: A0A142EIN2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS14950
gene id: 1727163:AO498_RS14950
uniprot id: A0A142ERJ6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1727163:AO498 RS11440
gene id: 1727163:AO498_RS11440
uniprot id: A0A142EPJ5
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

1727163:AO498 RS10745
gene id: 1727163:AO498_RS10745
uniprot id: A0A142EP53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1727163:AO498 RS04115
gene id: 1727163:AO498_RS04115
uniprot id: A0A142EKC2
names: Similarity
messages: Belongs to the RutC family.

1727163:AO498 RS07970
gene id: 1727163:AO498_RS07970
uniprot id: A0A142EMJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1727163:AO498 RS09575
gene id: 1727163:AO498_RS09575
uniprot id: A0A142ENG5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS03130
gene id: 1727163:AO498_RS03130
uniprot id: A0A142EJS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS05690
gene id: 1727163:AO498_RS05690
uniprot id: A0A142EL90
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1727163:AO498 RS05545
gene id: 1727163:AO498_RS05545
uniprot id: A0A142EL61
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1727163:AO498 RS13080
gene id: 1727163:AO498_RS13080
uniprot id: A0A142EQG9
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1727163:AO498 RS05385
gene id: 1727163:AO498_RS05385
uniprot id: A0A142EL32
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1727163:AO498 RS11080
gene id: 1727163:AO498_RS11080
uniprot id: A0A142EPC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1727163:AO498 RS16015
gene id: 1727163:AO498_RS16015
uniprot id: A0A142ES56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1727163:AO498 RS11015
gene id: 1727163:AO498_RS11015
uniprot id: A0A142EPA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS06035
gene id: 1727163:AO498_RS06035
uniprot id: A0A142ELF9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1727163:AO498 RS04485
gene id: 1727163:AO498_RS04485
uniprot id: A0A142EKJ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1727163:AO498 RS08785
gene id: 1727163:AO498_RS08785
uniprot id: A0A142EN06
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS03335
gene id: 1727163:AO498_RS03335
uniprot id: A0A142EJW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1727163:AO498 RS11880
gene id: 1727163:AO498_RS11880
uniprot id: A0A142EPT3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS06495
gene id: 1727163:AO498_RS06495
uniprot id: A0A142ELQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS12810
gene id: 1727163:AO498_RS12810
uniprot id: A0A142EQB5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1727163:AO498 RS12700
gene id: 1727163:AO498_RS12700
uniprot id: A0A142EQ94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1727163:AO498 RS08560
gene id: 1727163:AO498_RS08560
uniprot id: A0A142EMW0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1727163:AO498 RS16835
gene id: 1727163:AO498_RS16835
uniprot id: A0A142ESL3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1727163:AO498 RS03840
gene id: 1727163:AO498_RS03840
uniprot id: A0A142EK66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1727163:AO498 RS13310
gene id: 1727163:AO498_RS13310
uniprot id: A0A142EQL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1727163:AO498 RS08670
gene id: 1727163:AO498_RS08670
uniprot id: A0A142EMY3
names: Subunit
messages: Homodimer.

1727163:AO498 RS07860
gene id: 1727163:AO498_RS07860
uniprot id: A0A142EMH3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1727163:AO498 RS05980
gene id: 1727163:AO498_RS05980
uniprot id: A0A142ELE8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1727163:AO498 RS10185
gene id: 1727163:AO498_RS10185
uniprot id: A0A142ENU1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1727163:AO498 RS12145
gene id: 1727163:AO498_RS12145
uniprot id: A0A142EPY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1727163:AO498 RS01190
gene id: 1727163:AO498_RS01190
uniprot id: A0A142EIN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1727163:AO498 RS02660
gene id: 1727163:AO498_RS02660
uniprot id: A0A142EJH8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1727163:AO498 RS16355
gene id: 1727163:AO498_RS16355
uniprot id: A0A142ESC2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1727163:AO498 RS10415
gene id: 1727163:AO498_RS10415
uniprot id: A0A142ENY6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1727163:AO498 RS04805
gene id: 1727163:AO498_RS04805
uniprot id: A0A142EKR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1727163:AO498 RS15620
gene id: 1727163:AO498_RS15620
uniprot id: A0A142ERX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS06620
gene id: 1727163:AO498_RS06620
uniprot id: A0A142ELS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1727163:AO498 RS00270
gene id: 1727163:AO498_RS00270
uniprot id: A0A142EI53
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1727163:AO498 RS01355
gene id: 1727163:AO498_RS01355
uniprot id: A0A142EIR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1727163:AO498 RS00265
gene id: 1727163:AO498_RS00265
uniprot id: A0A142EI52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1727163:AO498 RS00875
gene id: 1727163:AO498_RS00875
uniprot id: A0A142EIG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1727163:AO498 RS14650
gene id: 1727163:AO498_RS14650
uniprot id: A0A142ERD5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1727163:AO498 RS01955
gene id: 1727163:AO498_RS01955
uniprot id: A0A142EJ35
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1727163:AO498 RS10650
gene id: 1727163:AO498_RS10650
uniprot id: A0A142EP33
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1727163:AO498 RS05420
gene id: 1727163:AO498_RS05420
uniprot id: A0A142EL39
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS03415
gene id: 1727163:AO498_RS03415
uniprot id: A0A142EJX9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1727163:AO498 RS11145
gene id: 1727163:AO498_RS11145
uniprot id: A0A142EPD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1727163:AO498 RS04755
gene id: 1727163:AO498_RS04755
uniprot id: A0A142EKQ0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1727163:AO498 RS09195
gene id: 1727163:AO498_RS09195
uniprot id: A0A142EN88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1727163:AO498 RS10680
gene id: 1727163:AO498_RS10680
uniprot id: A0A142EP39
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1727163:AO498 RS06590
gene id: 1727163:AO498_RS06590
uniprot id: A0A142ELR9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1727163:AO498 RS00395
gene id: 1727163:AO498_RS00395
uniprot id: A0A142EI77
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1727163:AO498 RS05195
gene id: 1727163:AO498_RS05195
uniprot id: A0A142EKZ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1727163:AO498 RS00090
gene id: 1727163:AO498_RS00090
uniprot id: A0A142EI16
names: Similarity
messages: Belongs to the aldose epimerase family.

1727163:AO498 RS07400
gene id: 1727163:AO498_RS07400
uniprot id: A0A142EM82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1727163:AO498 RS14815
gene id: 1727163:AO498_RS14815
uniprot id: A0A142ERG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1727163:AO498 RS08800
gene id: 1727163:AO498_RS08800
uniprot id: A0A142EN09
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1727163:AO498 RS13440
gene id: 1727163:AO498_RS13440
uniprot id: A0A142EQP2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1727163:AO498 RS04585
gene id: 1727163:AO498_RS04585
uniprot id: A0A142EKL6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1727163:AO498 RS14515
gene id: 1727163:AO498_RS14515
uniprot id: A0A142ERA8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS02125
gene id: 1727163:AO498_RS02125
uniprot id: A0A142EJ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1727163:AO498 RS06765
gene id: 1727163:AO498_RS06765
uniprot id: A0A142ELV4
names: Similarity
messages: Belongs to the universal stress protein A family.

1727163:AO498 RS05100
gene id: 1727163:AO498_RS05100
uniprot id: A0A142EKX1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1727163:AO498 RS05300
gene id: 1727163:AO498_RS05300
uniprot id: A0A142EL15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS15720
gene id: 1727163:AO498_RS15720
uniprot id: A0A142ERZ8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1727163:AO498 RS07165
gene id: 1727163:AO498_RS07165
uniprot id: A0A142EM34
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1727163:AO498 RS11345
gene id: 1727163:AO498_RS11345
uniprot id: A0A142EPH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1727163:AO498 RS10580
gene id: 1727163:AO498_RS10580
uniprot id: A0A142EP19
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS11780
gene id: 1727163:AO498_RS11780
uniprot id: A0A142EPR4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1727163:AO498 RS11540
gene id: 1727163:AO498_RS11540
uniprot id: A0A142EPL5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1727163:AO498 RS00665
gene id: 1727163:AO498_RS00665
uniprot id: A0A142EIC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1727163:AO498 RS00700
gene id: 1727163:AO498_RS00700
uniprot id: A0A142EID4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1727163:AO498 RS14370
gene id: 1727163:AO498_RS14370
uniprot id: A0A142ER79
names: Similarity
messages: Belongs to the YciI family.

1727163:AO498 RS12515
gene id: 1727163:AO498_RS12515
uniprot id: A0A142EQ58
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1727163:AO498 RS01600
gene id: 1727163:AO498_RS01600
uniprot id: A0A142EIW2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1727163:AO498 RS10775
gene id: 1727163:AO498_RS10775
uniprot id: A0A142EP59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1727163:AO498 RS13255
gene id: 1727163:AO498_RS13255
uniprot id: A0A142EQK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1727163:AO498 RS14485
gene id: 1727163:AO498_RS14485
uniprot id: A0A142ERA2
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1727163:AO498 RS05430
gene id: 1727163:AO498_RS05430
uniprot id: A0A142EL41
names: Similarity
messages: Belongs to the peptidase M1 family.

1727163:AO498 RS11460
gene id: 1727163:AO498_RS11460
uniprot id: A0A142EPJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1727163:AO498 RS13280
gene id: 1727163:AO498_RS13280
uniprot id: A0A142EQK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

1727163:AO498 RS15995
gene id: 1727163:AO498_RS15995
uniprot id: A0A142ES52
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1727163:AO498 RS14820
gene id: 1727163:AO498_RS14820
uniprot id: A0A142ERG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1727163:AO498 RS08180
gene id: 1727163:AO498_RS08180
uniprot id: A0A142EMN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1727163:AO498 RS13315
gene id: 1727163:AO498_RS13315
uniprot id: A0A142EQL6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1727163:AO498 RS04415
gene id: 1727163:AO498_RS04415
uniprot id: A0A142EKI3
names: Similarity
messages: Belongs to the CarB family.

1727163:AO498 RS14980
gene id: 1727163:AO498_RS14980
uniprot id: A0A142ERK2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS07875
gene id: 1727163:AO498_RS07875
uniprot id: A0A142EMH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1727163:AO498 RS08415
gene id: 1727163:AO498_RS08415
uniprot id: A0A142EMT1
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

1727163:AO498 RS16885
gene id: 1727163:AO498_RS16885
uniprot id: A0A142ESM3
names: Similarity
messages: Belongs to the thioredoxin family.

1727163:AO498 RS03710
gene id: 1727163:AO498_RS03710
uniprot id: A0A142EK40
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1727163:AO498 RS10630
gene id: 1727163:AO498_RS10630
uniprot id: A0A142EP29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1727163:AO498 RS01940
gene id: 1727163:AO498_RS01940
uniprot id: A0A142EJ32
names: Similarity
messages: Belongs to the glutamate synthase family.

1727163:AO498 RS16200
gene id: 1727163:AO498_RS16200
uniprot id: A0A142ES92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1727163:AO498 RS13100
gene id: 1727163:AO498_RS13100
uniprot id: A0A142EQH3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS06635
gene id: 1727163:AO498_RS06635
uniprot id: A0A142ELS8
names: Similarity
messages: Belongs to the ParB family.

1727163:AO498 RS00715
gene id: 1727163:AO498_RS00715
uniprot id: A0A142EID7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1727163:AO498 RS03515
gene id: 1727163:AO498_RS03515
uniprot id: A0A142EJZ9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1727163:AO498 RS08780
gene id: 1727163:AO498_RS08780
uniprot id: A0A142EN05
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS11605
gene id: 1727163:AO498_RS11605
uniprot id: A0A142EPM9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1727163:AO498 RS08915
gene id: 1727163:AO498_RS08915
uniprot id: A0A142EN32
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1727163:AO498 RS08125
gene id: 1727163:AO498_RS08125
uniprot id: A0A142EMM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1727163:AO498 RS02325
gene id: 1727163:AO498_RS02325
uniprot id: A0A142EJB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1727163:AO498 RS00375
gene id: 1727163:AO498_RS00375
uniprot id: A0A142EI73
names: Subcellular Location Annotation
messages: Cytoplasm

1727163:AO498 RS03620
gene id: 1727163:AO498_RS03620
uniprot id: A0A142EK21
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS01550
gene id: 1727163:AO498_RS01550
uniprot id: A0A142EIV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1727163:AO498 RS00885
gene id: 1727163:AO498_RS00885
uniprot id: A0A142EIH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1727163:AO498 RS10560
gene id: 1727163:AO498_RS10560
uniprot id: A0A142EP15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1727163:AO498 RS00025
gene id: 1727163:AO498_RS00025
uniprot id: A0A142EI03
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1727163:AO498 RS00765
gene id: 1727163:AO498_RS00765
uniprot id: A0A142EIE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1727163:AO498 RS14905
gene id: 1727163:AO498_RS14905
uniprot id: A0A142ERI7
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

1727163:AO498 RS11130
gene id: 1727163:AO498_RS11130
uniprot id: A0A142EPD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1727163:AO498 RS06350
gene id: 1727163:AO498_RS06350
uniprot id: A0A142ELM1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1727163:AO498 RS01930
gene id: 1727163:AO498_RS01930
uniprot id: A0A142EJ30
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1727163:AO498 RS10130
gene id: 1727163:AO498_RS10130
uniprot id: A0A142ENS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1727163:AO498 RS08355
gene id: 1727163:AO498_RS08355
uniprot id: A0A142EMR9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1727163:AO498 RS00285
gene id: 1727163:AO498_RS00285
uniprot id: A0A142EI56
names: Similarity
messages: Belongs to the peptidase M24B family.

1727163:AO498 RS16830
gene id: 1727163:AO498_RS16830
uniprot id: A0A142ESL2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS07900
gene id: 1727163:AO498_RS07900
uniprot id: A0A142EMI1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS06210
gene id: 1727163:AO498_RS06210
uniprot id: A0A142ELJ4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS02030
gene id: 1727163:AO498_RS02030
uniprot id: A0A142EJ51
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1727163:AO498 RS02050
gene id: 1727163:AO498_RS02050
uniprot id: A0A142EJ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1727163:AO498 RS04525
gene id: 1727163:AO498_RS04525
uniprot id: A0A142EKK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS01845
gene id: 1727163:AO498_RS01845
uniprot id: A0A142EJ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1727163:AO498 RS05535
gene id: 1727163:AO498_RS05535
uniprot id: A0A142EL59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1727163:AO498 RS03010
gene id: 1727163:AO498_RS03010
uniprot id: A0A142EJP6
names: Similarity
messages: Belongs to the asparagine synthetase family.

1727163:AO498 RS00705
gene id: 1727163:AO498_RS00705
uniprot id: A0A142EID5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1727163:AO498 RS06745
gene id: 1727163:AO498_RS06745
uniprot id: A0A142ELV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1727163:AO498 RS08565
gene id: 1727163:AO498_RS08565
uniprot id: A0A142EMW1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1727163:AO498 RS11060
gene id: 1727163:AO498_RS11060
uniprot id: A0A142EPB6
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1727163:AO498 RS12175
gene id: 1727163:AO498_RS12175
uniprot id: A0A142EPZ0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1727163:AO498 RS06585
gene id: 1727163:AO498_RS06585
uniprot id: A0A142ELR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1727163:AO498 RS02335
gene id: 1727163:AO498_RS02335
uniprot id: A0A142EJB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1727163:AO498 RS16850
gene id: 1727163:AO498_RS16850
uniprot id: A0A142ESL6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS09500
gene id: 1727163:AO498_RS09500
uniprot id: A0A142ENF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1727163:AO498 RS09425
gene id: 1727163:AO498_RS09425
uniprot id: A0A142END4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1727163:AO498 RS10655
gene id: 1727163:AO498_RS10655
uniprot id: A0A142EP34
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS00845
gene id: 1727163:AO498_RS00845
uniprot id: A0A142EIG3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1727163:AO498 RS05155
gene id: 1727163:AO498_RS05155
uniprot id: A0A142EKY2
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1727163:AO498 RS14500
gene id: 1727163:AO498_RS14500
uniprot id: A0A142ERA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1727163:AO498 RS05225
gene id: 1727163:AO498_RS05225
uniprot id: A0A142EKZ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1727163:AO498 RS11665
gene id: 1727163:AO498_RS11665
uniprot id: A0A142EPP1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS07670
gene id: 1727163:AO498_RS07670
uniprot id: A0A142EMD5
names: Similarity
messages: Belongs to the UPF0162 family.

1727163:AO498 RS01780
gene id: 1727163:AO498_RS01780
uniprot id: A0A142EIZ9
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1727163:AO498 RS14000
gene id: 1727163:AO498_RS14000
uniprot id: A0A142ER04
names: Similarity
messages: Belongs to the asparagine synthetase family.

1727163:AO498 RS04490
gene id: 1727163:AO498_RS04490
uniprot id: A0A142EKJ7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS02115
gene id: 1727163:AO498_RS02115
uniprot id: A0A142EJ68
names: Similarity
messages: Belongs to the universal stress protein A family.

1727163:AO498 RS03375
gene id: 1727163:AO498_RS03375
uniprot id: A0A142EJX0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

1727163:AO498 RS03815
gene id: 1727163:AO498_RS03815
uniprot id: A0A142EK61
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS12845
gene id: 1727163:AO498_RS12845
uniprot id: A0A142EQC2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1727163:AO498 RS09530
gene id: 1727163:AO498_RS09530
uniprot id: A0A142ENF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS06805
gene id: 1727163:AO498_RS06805
uniprot id: A0A142ELW2
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1727163:AO498 RS02215
gene id: 1727163:AO498_RS02215
uniprot id: A0A142EJ88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1727163:AO498 RS05670
gene id: 1727163:AO498_RS05670
uniprot id: A0A142EL86
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1727163:AO498 RS05665
gene id: 1727163:AO498_RS05665
uniprot id: A0A142EL85
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1727163:AO498 RS15200
gene id: 1727163:AO498_RS15200
uniprot id: A0A142ERP6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1727163:AO498 RS09605
gene id: 1727163:AO498_RS09605
uniprot id: A0A142ENH1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1727163:AO498 RS03535
gene id: 1727163:AO498_RS03535
uniprot id: A0A142EK03
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1727163:AO498 RS12375
gene id: 1727163:AO498_RS12375
uniprot id: A0A142EQ30
names: Similarity
messages: Belongs to the universal stress protein A family.

1727163:AO498 RS04100
gene id: 1727163:AO498_RS04100
uniprot id: A0A142EKB9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1727163:AO498 RS03485
gene id: 1727163:AO498_RS03485
uniprot id: A0A142EJZ3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1727163:AO498 RS07370
gene id: 1727163:AO498_RS07370
uniprot id: A0A142EM76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1727163:AO498 RS14225
gene id: 1727163:AO498_RS14225
uniprot id: A0A142ER50
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1727163:AO498 RS06920
gene id: 1727163:AO498_RS06920
uniprot id: A0A142ELY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1727163:AO498 RS05645
gene id: 1727163:AO498_RS05645
uniprot id: A0A142EL81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1727163:AO498 RS13860
gene id: 1727163:AO498_RS13860
uniprot id: A0A142EQX6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1727163:AO498 RS02105
gene id: 1727163:AO498_RS02105
uniprot id: A0A142EJ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS16465
gene id: 1727163:AO498_RS16465
uniprot id: A0A142ESE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS12790
gene id: 1727163:AO498_RS12790
uniprot id: A0A142EQB1
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1727163:AO498 RS11090
gene id: 1727163:AO498_RS11090
uniprot id: A0A142EPC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1727163:AO498 RS09640
gene id: 1727163:AO498_RS09640
uniprot id: A0A142ENH8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1727163:AO498 RS08400
gene id: 1727163:AO498_RS08400
uniprot id: A0A142EMS8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1727163:AO498 RS14155
gene id: 1727163:AO498_RS14155
uniprot id: A0A142ER35
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1727163:AO498 RS09830
gene id: 1727163:AO498_RS09830
uniprot id: A0A142ENL7
names: Similarity
messages: Belongs to the peptidase S66 family.

1727163:AO498 RS02510
gene id: 1727163:AO498_RS02510
uniprot id: A0A142EJE9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1727163:AO498 RS05760
gene id: 1727163:AO498_RS05760
uniprot id: A0A142ELA4
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

1727163:AO498 RS09075
gene id: 1727163:AO498_RS09075
uniprot id: A0A142EN64
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1727163:AO498 RS06545
gene id: 1727163:AO498_RS06545
uniprot id: A0A142ELR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1727163:AO498 RS14475
gene id: 1727163:AO498_RS14475
uniprot id: A0A142ERA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1727163:AO498 RS10215
gene id: 1727163:AO498_RS10215
uniprot id: A0A142ENU7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1727163:AO498 RS04810
gene id: 1727163:AO498_RS04810
uniprot id: A0A142EKR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1727163:AO498 RS11770
gene id: 1727163:AO498_RS11770
uniprot id: A0A142EPR2
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1727163:AO498 RS06150
gene id: 1727163:AO498_RS06150
uniprot id: A0A142ELI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1727163:AO498 RS13705
gene id: 1727163:AO498_RS13705
uniprot id: A0A142EQU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1727163:AO498 RS14695
gene id: 1727163:AO498_RS14695
uniprot id: A0A142ERE4
names: Similarity
messages: Belongs to the YicC/YloC family.

1727163:AO498 RS11970
gene id: 1727163:AO498_RS11970
uniprot id: A0A142EPV0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1727163:AO498 RS02980
gene id: 1727163:AO498_RS02980
uniprot id: A0A142EJP0
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS09210
gene id: 1727163:AO498_RS09210
uniprot id: A0A142EN91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1727163:AO498 RS09590
gene id: 1727163:AO498_RS09590
uniprot id: A0A142ENG8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1727163:AO498 RS07345
gene id: 1727163:AO498_RS07345
uniprot id: A0A142EM71
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1727163:AO498 RS07220
gene id: 1727163:AO498_RS07220
uniprot id: A0A142EM45
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS00145
gene id: 1727163:AO498_RS00145
uniprot id: A0A142EI27
names: Similarity
messages: Belongs to the UPF0758 family.

1727163:AO498 RS00945
gene id: 1727163:AO498_RS00945
uniprot id: A0A142EII2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1727163:AO498 RS06670
gene id: 1727163:AO498_RS06670
uniprot id: A0A142ELT5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1727163:AO498 RS01165
gene id: 1727163:AO498_RS01165
uniprot id: A0A142EIM5
names: Similarity
messages: Belongs to the universal stress protein A family.

1727163:AO498 RS09695
gene id: 1727163:AO498_RS09695
uniprot id: A0A142ENI9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1727163:AO498 RS11690
gene id: 1727163:AO498_RS11690
uniprot id: A0A142EPP6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1727163:AO498 RS02025
gene id: 1727163:AO498_RS02025
uniprot id: A0A142EJ50
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS15230
gene id: 1727163:AO498_RS15230
uniprot id: A0A142ERQ2
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS10355
gene id: 1727163:AO498_RS10355
uniprot id: A0A142ENX6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1727163:AO498 RS02180
gene id: 1727163:AO498_RS02180
uniprot id: A0A142EJ81
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1727163:AO498 RS13190
gene id: 1727163:AO498_RS13190
uniprot id: A0A142EQJ1
names: Similarity
messages: Belongs to the pyruvate kinase family.

1727163:AO498 RS16760
gene id: 1727163:AO498_RS16760
uniprot id: A0A142ESJ8
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

1727163:AO498 RS06930
gene id: 1727163:AO498_RS06930
uniprot id: A0A142ELY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1727163:AO498 RS16680
gene id: 1727163:AO498_RS16680
uniprot id: A0A142ESI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1727163:AO498 RS01615
gene id: 1727163:AO498_RS01615
uniprot id: A0A142EIW5
names: Similarity
messages: Belongs to the arginase family.

1727163:AO498 RS12295
gene id: 1727163:AO498_RS12295
uniprot id: A0A142EQ14
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1727163:AO498 RS05730
gene id: 1727163:AO498_RS05730
uniprot id: A0A142EL98
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1727163:AO498 RS02270
gene id: 1727163:AO498_RS02270
uniprot id: A0A142EJ99
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1727163:AO498 RS15840
gene id: 1727163:AO498_RS15840
uniprot id: A0A142ES22
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1727163:AO498 RS05625
gene id: 1727163:AO498_RS05625
uniprot id: A0A142EL77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1727163:AO498 RS12460
gene id: 1727163:AO498_RS12460
uniprot id: A0A142EQ47
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1727163:AO498 RS05975
gene id: 1727163:AO498_RS05975
uniprot id: A0A142ELE7
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1727163:AO498 RS01925
gene id: 1727163:AO498_RS01925
uniprot id: A0A142EJ29
names: Similarity
messages: Belongs to the Nth/MutY family.

1727163:AO498 RS09190
gene id: 1727163:AO498_RS09190
uniprot id: A0A142EN87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1727163:AO498 RS11000
gene id: 1727163:AO498_RS11000
uniprot id: A0A142EPA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1727163:AO498 RS08610
gene id: 1727163:AO498_RS08610
uniprot id: A0A142EMX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1727163:AO498 RS06520
gene id: 1727163:AO498_RS06520
uniprot id: A0A142ELQ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1727163:AO498 RS12485
gene id: 1727163:AO498_RS12485
uniprot id: A0A142EQ52
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1727163:AO498 RS15510
gene id: 1727163:AO498_RS15510
uniprot id: A0A142ERV6
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS02815
gene id: 1727163:AO498_RS02815
uniprot id: A0A142EJK7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1727163:AO498 RS16145
gene id: 1727163:AO498_RS16145
uniprot id: A0A142ES81
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1727163:AO498 RS04915
gene id: 1727163:AO498_RS04915
uniprot id: A0A142EKT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1727163:AO498 RS09160
gene id: 1727163:AO498_RS09160
uniprot id: A0A142EN81
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1727163:AO498 RS01350
gene id: 1727163:AO498_RS01350
uniprot id: A0A142EIR2
names: Similarity
messages: Belongs to the sulfatase family.

1727163:AO498 RS05590
gene id: 1727163:AO498_RS05590
uniprot id: A0A142EL70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1727163:AO498 RS10645
gene id: 1727163:AO498_RS10645
uniprot id: A0A142EP32
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS02880
gene id: 1727163:AO498_RS02880
uniprot id: A0A142EJM0
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1727163:AO498 RS10740
gene id: 1727163:AO498_RS10740
uniprot id: A0A142EP52
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1727163:AO498 RS00895
gene id: 1727163:AO498_RS00895
uniprot id: A0A142EIH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

1727163:AO498 RS00535
gene id: 1727163:AO498_RS00535
uniprot id: A0A142EIA1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1727163:AO498 RS08890
gene id: 1727163:AO498_RS08890
uniprot id: A0A142EN27
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS04400
gene id: 1727163:AO498_RS04400
uniprot id: A0A142EKI0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1727163:AO498 RS01405
gene id: 1727163:AO498_RS01405
uniprot id: A0A142EIS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1727163:AO498 RS12465
gene id: 1727163:AO498_RS12465
uniprot id: A0A142EQ48
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1727163:AO498 RS06135
gene id: 1727163:AO498_RS06135
uniprot id: A0A142ELH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1727163:AO498 RS11905
gene id: 1727163:AO498_RS11905
uniprot id: A0A142EPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1727163:AO498 RS15745
gene id: 1727163:AO498_RS15745
uniprot id: A0A142ES03
names: Similarity
messages: Belongs to the peptidase S33 family.

1727163:AO498 RS01860
gene id: 1727163:AO498_RS01860
uniprot id: A0A142EJ15
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1727163:AO498 RS08620
gene id: 1727163:AO498_RS08620
uniprot id: A0A142EMX3
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS03345
gene id: 1727163:AO498_RS03345
uniprot id: A0A142EJW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1727163:AO498 RS15780
gene id: 1727163:AO498_RS15780
uniprot id: A0A142ES10
names: Similarity
messages: Belongs to the SusD family.

1727163:AO498 RS05560
gene id: 1727163:AO498_RS05560
uniprot id: A0A142EL64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1727163:AO498 RS16285
gene id: 1727163:AO498_RS16285
uniprot id: A0A142ESA8
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS07120
gene id: 1727163:AO498_RS07120
uniprot id: A0A142EM25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS04130
gene id: 1727163:AO498_RS04130
uniprot id: A0A142EKC5
names: Similarity
messages: Belongs to the DinB family.

1727163:AO498 RS04695
gene id: 1727163:AO498_RS04695
uniprot id: A0A142EKN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1727163:AO498 RS09125
gene id: 1727163:AO498_RS09125
uniprot id: A0A142EN74
names: Similarity
messages: Belongs to the sulfatase family.

1727163:AO498 RS01070
gene id: 1727163:AO498_RS01070
uniprot id: A0A142EIK6
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS02160
gene id: 1727163:AO498_RS02160
uniprot id: A0A142EJ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1727163:AO498 RS12615
gene id: 1727163:AO498_RS12615
uniprot id: A0A142EQ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

1727163:AO498 RS00805
gene id: 1727163:AO498_RS00805
uniprot id: A0A142EIF5
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS14645
gene id: 1727163:AO498_RS14645
uniprot id: A0A142ERD4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1727163:AO498 RS11755
gene id: 1727163:AO498_RS11755
uniprot id: A0A142EPQ9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1727163:AO498 RS00620
gene id: 1727163:AO498_RS00620
uniprot id: A0A142EIB8
names: Similarity
messages: Belongs to the UPF0102 family.

1727163:AO498 RS16385
gene id: 1727163:AO498_RS16385
uniprot id: A0A142ESC8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1727163:AO498 RS12605
gene id: 1727163:AO498_RS12605
uniprot id: A0A142EQ75
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS01815
gene id: 1727163:AO498_RS01815
uniprot id: A0A142EJ06
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS07140
gene id: 1727163:AO498_RS07140
uniprot id: A0A142EM29
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS00470
gene id: 1727163:AO498_RS00470
uniprot id: A0A142EI88
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS00380
gene id: 1727163:AO498_RS00380
uniprot id: A0A142EI74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1727163:AO498 RS14190
gene id: 1727163:AO498_RS14190
uniprot id: A0A142ER42
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS08000
gene id: 1727163:AO498_RS08000
uniprot id: A0A142EMK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1727163:AO498 RS00455
gene id: 1727163:AO498_RS00455
uniprot id: A0A142EI85
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1727163:AO498 RS05450
gene id: 1727163:AO498_RS05450
uniprot id: A0A142EL42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1727163:AO498 RS08850
gene id: 1727163:AO498_RS08850
uniprot id: A0A142EN19
names: Similarity
messages: Belongs to the pyruvate kinase family.

1727163:AO498 RS09585
gene id: 1727163:AO498_RS09585
uniprot id: A0A142ENG7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1727163:AO498 RS12170
gene id: 1727163:AO498_RS12170
uniprot id: A0A142EPY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1727163:AO498 RS01585
gene id: 1727163:AO498_RS01585
uniprot id: A0A142EIV9
names: Similarity
messages: Belongs to the Skp family.

1727163:AO498 RS11325
gene id: 1727163:AO498_RS11325
uniprot id: A0A142EPH1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS06280
gene id: 1727163:AO498_RS06280
uniprot id: A0A142ELK7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1727163:AO498 RS05950
gene id: 1727163:AO498_RS05950
uniprot id: A0A142ELE2
names: Similarity
messages: Belongs to the RelE toxin family.

1727163:AO498 RS05990
gene id: 1727163:AO498_RS05990
uniprot id: A0A142ELF0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1727163:AO498 RS00385
gene id: 1727163:AO498_RS00385
uniprot id: A0A142EI75
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1727163:AO498 RS10300
gene id: 1727163:AO498_RS10300
uniprot id: A0A142ENW5
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS04785
gene id: 1727163:AO498_RS04785
uniprot id: A0A142EKQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1727163:AO498 RS10350
gene id: 1727163:AO498_RS10350
uniprot id: A0A142ENX5
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS06775
gene id: 1727163:AO498_RS06775
uniprot id: A0A142ELV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1727163:AO498 RS16235
gene id: 1727163:AO498_RS16235
uniprot id: A0A142ES99
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1727163:AO498 RS07605
gene id: 1727163:AO498_RS07605
uniprot id: A0A142EMC2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1727163:AO498 RS16280
gene id: 1727163:AO498_RS16280
uniprot id: A0A142ESA7
names: Subcellular Location Annotation
messages: Cytoplasm

1727163:AO498 RS01655
gene id: 1727163:AO498_RS01655
uniprot id: A0A142EIX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1727163:AO498 RS15005
gene id: 1727163:AO498_RS15005
uniprot id: A0A142ERK7
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

1727163:AO498 RS12895
gene id: 1727163:AO498_RS12895
uniprot id: A0A142EQD2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS13225
gene id: 1727163:AO498_RS13225
uniprot id: A0A142EQJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1727163:AO498 RS10140
gene id: 1727163:AO498_RS10140
uniprot id: A0A142ENT1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1727163:AO498 RS06460
gene id: 1727163:AO498_RS06460
uniprot id: A0A142ELP3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1727163:AO498 RS05210
gene id: 1727163:AO498_RS05210
uniprot id: A0A142EKZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1727163:AO498 RS12855
gene id: 1727163:AO498_RS12855
uniprot id: A0A142EQC4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1727163:AO498 RS11335
gene id: 1727163:AO498_RS11335
uniprot id: A0A142EPH3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1727163:AO498 RS00135
gene id: 1727163:AO498_RS00135
uniprot id: A0A142EI25
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1727163:AO498 RS13865
gene id: 1727163:AO498_RS13865
uniprot id: A0A142EQX7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1727163:AO498 RS08325
gene id: 1727163:AO498_RS08325
uniprot id: A0A142EMR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1727163:AO498 RS15925
gene id: 1727163:AO498_RS15925
uniprot id: A0A142ES39
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1727163:AO498 RS01985
gene id: 1727163:AO498_RS01985
uniprot id: A0A142EJ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1727163:AO498 RS16020
gene id: 1727163:AO498_RS16020
uniprot id: A0A142ES57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1727163:AO498 RS03570
gene id: 1727163:AO498_RS03570
uniprot id: A0A142EK10
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1727163:AO498 RS01620
gene id: 1727163:AO498_RS01620
uniprot id: A0A142EIW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1727163:AO498 RS14910
gene id: 1727163:AO498_RS14910
uniprot id: A0A142ERI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1727163:AO498 RS04780
gene id: 1727163:AO498_RS04780
uniprot id: A0A142EKQ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1727163:AO498 RS15245
gene id: 1727163:AO498_RS15245
uniprot id: A0A142ERQ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1727163:AO498 RS00995
gene id: 1727163:AO498_RS00995
uniprot id: A0A142EIJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1727163:AO498 RS07585
gene id: 1727163:AO498_RS07585
uniprot id: A0A142EMB9
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS07185
gene id: 1727163:AO498_RS07185
uniprot id: A0A142EM38
names: Subcellular Location Annotation
messages: Cytoplasm

1727163:AO498 RS10670
gene id: 1727163:AO498_RS10670
uniprot id: A0A142EP37
names: Similarity
messages: Belongs to the histone deacetylase family.

1727163:AO498 RS06850
gene id: 1727163:AO498_RS06850
uniprot id: A0A142ELX1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1727163:AO498 RS04905
gene id: 1727163:AO498_RS04905
uniprot id: A0A142EKT1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1727163:AO498 RS04140
gene id: 1727163:AO498_RS04140
uniprot id: A0A142EKC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1727163:AO498 RS03235
gene id: 1727163:AO498_RS03235
uniprot id: A0A142EJU1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1727163:AO498 RS14085
gene id: 1727163:AO498_RS14085
uniprot id: A0A142ER21
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1727163:AO498 RS00825
gene id: 1727163:AO498_RS00825
uniprot id: A0A142EIF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1727163:AO498 RS16150
gene id: 1727163:AO498_RS16150
uniprot id: A0A142ES82
names: Similarity
messages: Belongs to the fabD family.

1727163:AO498 RS01960
gene id: 1727163:AO498_RS01960
uniprot id: A0A142EJ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1727163:AO498 RS01380
gene id: 1727163:AO498_RS01380
uniprot id: A0A142EIR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1727163:AO498 RS05520
gene id: 1727163:AO498_RS05520
uniprot id: A0A142EL55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1727163:AO498 RS11125
gene id: 1727163:AO498_RS11125
uniprot id: A0A142EPC9
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS01065
gene id: 1727163:AO498_RS01065
uniprot id: A0A142EIK5
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS02565
gene id: 1727163:AO498_RS02565
uniprot id: A0A142EJG0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1727163:AO498 RS10095
gene id: 1727163:AO498_RS10095
uniprot id: A0A142ENS2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1727163:AO498 RS12165
gene id: 1727163:AO498_RS12165
uniprot id: A0A142EPY8
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1727163:AO498 RS00220
gene id: 1727163:AO498_RS00220
uniprot id: A0A142EI43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1727163:AO498 RS15225
gene id: 1727163:AO498_RS15225
uniprot id: A0A142ERQ1
names: Similarity
messages: Belongs to the SCO1/2 family.

1727163:AO498 RS04960
gene id: 1727163:AO498_RS04960
uniprot id: A0A142EKU3
names: Similarity
messages: Belongs to the SusD family.

1727163:AO498 RS03695
gene id: 1727163:AO498_RS03695
uniprot id: A0A142EK37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1727163:AO498 RS16205
gene id: 1727163:AO498_RS16205
uniprot id: A0A142ES93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1727163:AO498 RS11510
gene id: 1727163:AO498_RS11510
uniprot id: A0A142EPK9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1727163:AO498 RS06380
gene id: 1727163:AO498_RS06380
uniprot id: A0A142ELM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1727163:AO498 RS09565
gene id: 1727163:AO498_RS09565
uniprot id: A0A142ENG3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1727163:AO498 RS09320
gene id: 1727163:AO498_RS09320
uniprot id: A0A142ENB3
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS09925
gene id: 1727163:AO498_RS09925
uniprot id: A0A142ENN7
names: Similarity
messages: Belongs to the universal stress protein A family.

1727163:AO498 RS15860
gene id: 1727163:AO498_RS15860
uniprot id: A0A142ES26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
messages: Monomer.
messages: Periplasm

1727163:AO498 RS08425
gene id: 1727163:AO498_RS08425
uniprot id: A0A142EMT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1727163:AO498 RS05610
gene id: 1727163:AO498_RS05610
uniprot id: A0A142EL74
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1727163:AO498 RS13385
gene id: 1727163:AO498_RS13385
uniprot id: A0A142EQN1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1727163:AO498 RS14255
gene id: 1727163:AO498_RS14255
uniprot id: A0A142ER56
names: Similarity
messages: Belongs to the citrate synthase family.

1727163:AO498 RS07530
gene id: 1727163:AO498_RS07530
uniprot id: A0A142EMA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1727163:AO498 RS09110
gene id: 1727163:AO498_RS09110
uniprot id: A0A142EN71
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS01965
gene id: 1727163:AO498_RS01965
uniprot id: A0A142EJ37
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1727163:AO498 RS11115
gene id: 1727163:AO498_RS11115
uniprot id: A0A142EPC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1727163:AO498 RS03920
gene id: 1727163:AO498_RS03920
uniprot id: A0A142EK82
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1727163:AO498 RS01545
gene id: 1727163:AO498_RS01545
uniprot id: A0A142EIV1
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1727163:AO498 RS05325
gene id: 1727163:AO498_RS05325
uniprot id: A0A142EL20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS15365
gene id: 1727163:AO498_RS15365
uniprot id: A0A142ERS8
names: Subcellular Location Annotation
messages: Nucleus

1727163:AO498 RS12345
gene id: 1727163:AO498_RS12345
uniprot id: A0A142EQ24
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1727163:AO498 RS05275
gene id: 1727163:AO498_RS05275
uniprot id: A0A142EL09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1727163:AO498 RS04065
gene id: 1727163:AO498_RS04065
uniprot id: A0A142EKB2
names: Similarity
messages: Belongs to the hyi family.

1727163:AO498 RS03830
gene id: 1727163:AO498_RS03830
uniprot id: A0A142EK64
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1727163:AO498 RS01580
gene id: 1727163:AO498_RS01580
uniprot id: A0A142EIV8
names: Similarity
messages: Belongs to the Skp family.

1727163:AO498 RS09505
gene id: 1727163:AO498_RS09505
uniprot id: A0A142ENF1
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS11285
gene id: 1727163:AO498_RS11285
uniprot id: A0A142EPG4
names: Similarity
messages: Belongs to the CvfB family.

1727163:AO498 RS16110
gene id: 1727163:AO498_RS16110
uniprot id: A0A142ES74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1727163:AO498 RS02840
gene id: 1727163:AO498_RS02840
uniprot id: A0A142EJL2
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS06645
gene id: 1727163:AO498_RS06645
uniprot id: A0A142ELT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1727163:AO498 RS08555
gene id: 1727163:AO498_RS08555
uniprot id: A0A142EMV9
names: Similarity
messages: Belongs to the GARS family.

1727163:AO498 RS07455
gene id: 1727163:AO498_RS07455
uniprot id: A0A142EM93
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1727163:AO498 RS00230
gene id: 1727163:AO498_RS00230
uniprot id: A0A142EI45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1727163:AO498 RS04270
gene id: 1727163:AO498_RS04270
uniprot id: A0A142EKF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1727163:AO498 RS01560
gene id: 1727163:AO498_RS01560
uniprot id: A0A142EIV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS16705
gene id: 1727163:AO498_RS16705
uniprot id: A0A142ESI7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1727163:AO498 RS12040
gene id: 1727163:AO498_RS12040
uniprot id: A0A142EPW4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1727163:AO498 RS00950
gene id: 1727163:AO498_RS00950
uniprot id: A0A142EII3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1727163:AO498 RS01630
gene id: 1727163:AO498_RS01630
uniprot id: A0A142EIW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1727163:AO498 RS16865
gene id: 1727163:AO498_RS16865
uniprot id: A0A142ESL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1727163:AO498 RS13645
gene id: 1727163:AO498_RS13645
uniprot id: A0A142EQT3
names: Function
names: Similarity
messages: Belongs to the rhamnosyl O-methyltransferase family.
messages: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).

1727163:AO498 RS12450
gene id: 1727163:AO498_RS12450
uniprot id: A0A142EQ45
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1727163:AO498 RS01525
gene id: 1727163:AO498_RS01525
uniprot id: A0A142EIU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1727163:AO498 RS15955
gene id: 1727163:AO498_RS15955
uniprot id: A0A142ES45
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS12580
gene id: 1727163:AO498_RS12580
uniprot id: A0A142EQ70
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS15240
gene id: 1727163:AO498_RS15240
uniprot id: A0A142ERQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1727163:AO498 RS09975
gene id: 1727163:AO498_RS09975
uniprot id: A0A142ENP7
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1727163:AO498 RS09135
gene id: 1727163:AO498_RS09135
uniprot id: A0A142EN76
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1727163:AO498 RS01775
gene id: 1727163:AO498_RS01775
uniprot id: A0A142EIZ8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1727163:AO498 RS14665
gene id: 1727163:AO498_RS14665
uniprot id: A0A142ERD8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1727163:AO498 RS05615
gene id: 1727163:AO498_RS05615
uniprot id: A0A142EL75
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1727163:AO498 RS09370
gene id: 1727163:AO498_RS09370
uniprot id: A0A142ENC3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1727163:AO498 RS03225
gene id: 1727163:AO498_RS03225
uniprot id: A0A142EJT9
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS08130
gene id: 1727163:AO498_RS08130
uniprot id: A0A142EMM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1727163:AO498 RS12835
gene id: 1727163:AO498_RS12835
uniprot id: A0A142EQC0
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS08855
gene id: 1727163:AO498_RS08855
uniprot id: A0A142EN20
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS16030
gene id: 1727163:AO498_RS16030
uniprot id: A0A142ES59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1727163:AO498 RS10475
gene id: 1727163:AO498_RS10475
uniprot id: A0A142ENZ8
names: Similarity
messages: Belongs to the peptidase S8 family.

1727163:AO498 RS07935
gene id: 1727163:AO498_RS07935
uniprot id: A0A142EMI8
names: Similarity
messages: Belongs to the SusD family.

1727163:AO498 RS11150
gene id: 1727163:AO498_RS11150
uniprot id: A0A142EPD4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1727163:AO498 RS15635
gene id: 1727163:AO498_RS15635
uniprot id: A0A142ERY1
names: Similarity
messages: Belongs to the sulfatase family.

1727163:AO498 RS08625
gene id: 1727163:AO498_RS08625
uniprot id: A0A142EMX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1727163:AO498 RS03170
gene id: 1727163:AO498_RS03170
uniprot id: A0A142EJS8
names: Similarity
messages: Belongs to the sterol desaturase family.

1727163:AO498 RS04765
gene id: 1727163:AO498_RS04765
uniprot id: A0A142EKQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS11070
gene id: 1727163:AO498_RS11070
uniprot id: A0A142EPB8
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS11350
gene id: 1727163:AO498_RS11350
uniprot id: A0A142EPH7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS00900
gene id: 1727163:AO498_RS00900
uniprot id: A0A142EIH3
names: Similarity
messages: Belongs to the fructosamine kinase family.

1727163:AO498 RS02780
gene id: 1727163:AO498_RS02780
uniprot id: A0A142EJK0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1727163:AO498 RS07310
gene id: 1727163:AO498_RS07310
uniprot id: A0A142EM63
names: Similarity
messages: Belongs to the TrpF family.

1727163:AO498 RS04815
gene id: 1727163:AO498_RS04815
uniprot id: A0A142EKR2
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS09995
gene id: 1727163:AO498_RS09995
uniprot id: A0A142ENQ1
names: Similarity
messages: Belongs to the SusD family.

1727163:AO498 RS12765
gene id: 1727163:AO498_RS12765
uniprot id: A0A142EQA6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1727163:AO498 RS05415
gene id: 1727163:AO498_RS05415
uniprot id: A0A142EL38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1727163:AO498 RS11495
gene id: 1727163:AO498_RS11495
uniprot id: A0A142EPK6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1727163:AO498 RS00080
gene id: 1727163:AO498_RS00080
uniprot id: A0A142EI14
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1727163:AO498 RS09230
gene id: 1727163:AO498_RS09230
uniprot id: A0A142EN95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1727163:AO498 RS16675
gene id: 1727163:AO498_RS16675
uniprot id: A0A142ESI0
names: Similarity
messages: Belongs to the peptidase S41A family.

1727163:AO498 RS10810
gene id: 1727163:AO498_RS10810
uniprot id: A0A142EP66
names: Similarity
messages: Belongs to the peptidase S9C family.

1727163:AO498 RS04730
gene id: 1727163:AO498_RS04730
uniprot id: A0A142EKP5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS15960
gene id: 1727163:AO498_RS15960
uniprot id: A0A142ES46
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS11140
gene id: 1727163:AO498_RS11140
uniprot id: A0A142EPD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1727163:AO498 RS00745
gene id: 1727163:AO498_RS00745
uniprot id: A0A142EIE3
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS05135
gene id: 1727163:AO498_RS05135
uniprot id: A0A142EKX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1727163:AO498 RS14600
gene id: 1727163:AO498_RS14600
uniprot id: A0A142ERC5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1727163:AO498 RS07375
gene id: 1727163:AO498_RS07375
uniprot id: A0A142EM77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1727163:AO498 RS03410
gene id: 1727163:AO498_RS03410
uniprot id: A0A142EJX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1727163:AO498 RS04565
gene id: 1727163:AO498_RS04565
uniprot id: A0A142EKL2
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS03660
gene id: 1727163:AO498_RS03660
uniprot id: A0A142EK30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1727163:AO498 RS02170
gene id: 1727163:AO498_RS02170
uniprot id: A0A142EJ79
names: Similarity
messages: Belongs to the peptidase S8 family.

1727163:AO498 RS07470
gene id: 1727163:AO498_RS07470
uniprot id: A0A142EM96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1727163:AO498 RS06130
gene id: 1727163:AO498_RS06130
uniprot id: A0A142ELH8
names: Similarity
messages: Belongs to the SCO1/2 family.

1727163:AO498 RS04605
gene id: 1727163:AO498_RS04605
uniprot id: A0A142EKM0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1727163:AO498 RS03925
gene id: 1727163:AO498_RS03925
uniprot id: A0A142EK83
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1727163:AO498 RS12725
gene id: 1727163:AO498_RS12725
uniprot id: A0A142EQ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

1727163:AO498 RS00840
gene id: 1727163:AO498_RS00840
uniprot id: A0A142EIG2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1727163:AO498 RS09730
gene id: 1727163:AO498_RS09730
uniprot id: A0A142ENJ7
names: Similarity
messages: Belongs to the peptidase U62 family.

1727163:AO498 RS14140
gene id: 1727163:AO498_RS14140
uniprot id: A0A142ER32
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1727163:AO498 RS07390
gene id: 1727163:AO498_RS07390
uniprot id: A0A142EM80
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1727163:AO498 RS05390
gene id: 1727163:AO498_RS05390
uniprot id: A0A142EL33
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1727163:AO498 RS09070
gene id: 1727163:AO498_RS09070
uniprot id: A0A142EN63
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1727163:AO498 RS12915
gene id: 1727163:AO498_RS12915
uniprot id: A0A142EQD6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1727163:AO498 RS03810
gene id: 1727163:AO498_RS03810
uniprot id: A0A142EK60
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1727163:AO498 RS04940
gene id: 1727163:AO498_RS04940
uniprot id: A0A142EKT9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS11735
gene id: 1727163:AO498_RS11735
uniprot id: A0A142EPQ5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1727163:AO498 RS10150
gene id: 1727163:AO498_RS10150
uniprot id: A0A142ENT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1727163:AO498 RS02730
gene id: 1727163:AO498_RS02730
uniprot id: A0A142EJJ0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1727163:AO498 RS04705
gene id: 1727163:AO498_RS04705
uniprot id: A0A142EKP0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1727163:AO498 RS06905
gene id: 1727163:AO498_RS06905
uniprot id: A0A142ELY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1727163:AO498 RS09090
gene id: 1727163:AO498_RS09090
uniprot id: A0A142EN67
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS16005
gene id: 1727163:AO498_RS16005
uniprot id: A0A142ES54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS13220
gene id: 1727163:AO498_RS13220
uniprot id: A0A142EQJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1727163:AO498 RS03940
gene id: 1727163:AO498_RS03940
uniprot id: A0A142EK86
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1727163:AO498 RS05605
gene id: 1727163:AO498_RS05605
uniprot id: A0A142EL73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1727163:AO498 RS05495
gene id: 1727163:AO498_RS05495
uniprot id: A0A142EL50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1727163:AO498 RS07650
gene id: 1727163:AO498_RS07650
uniprot id: A0A142EMD1
names: Similarity
messages: Belongs to the arginine deiminase family.

1727163:AO498 RS04835
gene id: 1727163:AO498_RS04835
uniprot id: A0A142EKR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1727163:AO498 RS11545
gene id: 1727163:AO498_RS11545
uniprot id: A0A142EPL6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS01235
gene id: 1727163:AO498_RS01235
uniprot id: A0A142EIN9
names: Similarity
messages: Belongs to the peptidase M1 family.

1727163:AO498 RS11100
gene id: 1727163:AO498_RS11100
uniprot id: A0A142EPC4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1727163:AO498 RS00780
gene id: 1727163:AO498_RS00780
uniprot id: A0A142EIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1727163:AO498 RS03095
gene id: 1727163:AO498_RS03095
uniprot id: A0A142EJR3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1727163:AO498 RS04465
gene id: 1727163:AO498_RS04465
uniprot id: A0A142EKJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1727163:AO498 RS06010
gene id: 1727163:AO498_RS06010
uniprot id: A0A142ELF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS05780
gene id: 1727163:AO498_RS05780
uniprot id: A0A142ELA8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1727163:AO498 RS15645
gene id: 1727163:AO498_RS15645
uniprot id: A0A142ERY3
names: Similarity
messages: Belongs to the sulfatase family.

1727163:AO498 RS01880
gene id: 1727163:AO498_RS01880
uniprot id: A0A142EJ19
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1727163:AO498 RS05765
gene id: 1727163:AO498_RS05765
uniprot id: A0A142ELA5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS06705
gene id: 1727163:AO498_RS06705
uniprot id: A0A142ELU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1727163:AO498 RS14230
gene id: 1727163:AO498_RS14230
uniprot id: A0A142ER51
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1727163:AO498 RS06925
gene id: 1727163:AO498_RS06925
uniprot id: A0A142ELY6
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS13785
gene id: 1727163:AO498_RS13785
uniprot id: A0A142EQW1
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1727163:AO498 RS06500
gene id: 1727163:AO498_RS06500
uniprot id: A0A142ELQ2
names: Similarity
messages: Belongs to the SusD family.

1727163:AO498 RS13215
gene id: 1727163:AO498_RS13215
uniprot id: A0A142EQJ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS00710
gene id: 1727163:AO498_RS00710
uniprot id: A0A142EID6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1727163:AO498 RS03055
gene id: 1727163:AO498_RS03055
uniprot id: A0A142EJQ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1727163:AO498 RS01895
gene id: 1727163:AO498_RS01895
uniprot id: A0A142EJ22
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1727163:AO498 RS01830
gene id: 1727163:AO498_RS01830
uniprot id: A0A142EJ09
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1727163:AO498 RS07520
gene id: 1727163:AO498_RS07520
uniprot id: A0A142EMA6
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS12155
gene id: 1727163:AO498_RS12155
uniprot id: A0A142EPY6
names: Similarity
messages: Belongs to the DprA/Smf family.

1727163:AO498 RS05910
gene id: 1727163:AO498_RS05910
uniprot id: A0A142ELD4
names: Similarity
messages: Belongs to the sulfatase family.

1727163:AO498 RS08790
gene id: 1727163:AO498_RS08790
uniprot id: A0A142EN07
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS14280
gene id: 1727163:AO498_RS14280
uniprot id: A0A142ER61
names: Subunit
messages: Homodimer.

1727163:AO498 RS13205
gene id: 1727163:AO498_RS13205
uniprot id: A0A142EQJ4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1727163:AO498 RS13370
gene id: 1727163:AO498_RS13370
uniprot id: A0A142EQM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1727163:AO498 RS13660
gene id: 1727163:AO498_RS13660
uniprot id: A0A142EQT5
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

1727163:AO498 RS01570
gene id: 1727163:AO498_RS01570
uniprot id: A0A142EIV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1727163:AO498 RS04125
gene id: 1727163:AO498_RS04125
uniprot id: A0A142EKC4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1727163:AO498 RS00280
gene id: 1727163:AO498_RS00280
uniprot id: A0A142EI55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1727163:AO498 RS04670
gene id: 1727163:AO498_RS04670
uniprot id: A0A142EKN3
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

1727163:AO498 RS11785
gene id: 1727163:AO498_RS11785
uniprot id: A0A142EPR5
names: Similarity
messages: Belongs to the peptidase M13 family.

1727163:AO498 RS09035
gene id: 1727163:AO498_RS09035
uniprot id: A0A142EN56
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1727163:AO498 RS02185
gene id: 1727163:AO498_RS02185
uniprot id: A0A142EJ82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1727163:AO498 RS05550
gene id: 1727163:AO498_RS05550
uniprot id: A0A142EL62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1727163:AO498 RS07960
gene id: 1727163:AO498_RS07960
uniprot id: A0A142EMJ3
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1727163:AO498 RS16240
gene id: 1727163:AO498_RS16240
uniprot id: A0A142ESA0
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS12410
gene id: 1727163:AO498_RS12410
uniprot id: A0A142EQ37
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS13360
gene id: 1727163:AO498_RS13360
uniprot id: A0A142EQM5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1727163:AO498 RS05685
gene id: 1727163:AO498_RS05685
uniprot id: A0A142EL89
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1727163:AO498 RS06650
gene id: 1727163:AO498_RS06650
uniprot id: A0A142ELT1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS02440
gene id: 1727163:AO498_RS02440
uniprot id: A0A142EJD5
names: Similarity
messages: Belongs to the UPF0047 family.

1727163:AO498 RS04060
gene id: 1727163:AO498_RS04060
uniprot id: A0A142EKB1
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1727163:AO498 RS16820
gene id: 1727163:AO498_RS16820
uniprot id: A0A142ESL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1727163:AO498 RS16800
gene id: 1727163:AO498_RS16800
uniprot id: A0A142ESK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1727163:AO498 RS00960
gene id: 1727163:AO498_RS00960
uniprot id: A0A142EII5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1727163:AO498 RS13365
gene id: 1727163:AO498_RS13365
uniprot id: A0A142EQM6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1727163:AO498 RS02580
gene id: 1727163:AO498_RS02580
uniprot id: A0A142EJG3
names: Similarity
messages: Belongs to the peptidase S9C family.

1727163:AO498 RS10235
gene id: 1727163:AO498_RS10235
uniprot id: A0A142ENV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1727163:AO498 RS13730
gene id: 1727163:AO498_RS13730
uniprot id: A0A142EQV0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1727163:AO498 RS01665
gene id: 1727163:AO498_RS01665
uniprot id: A0A142EIX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1727163:AO498 RS15940
gene id: 1727163:AO498_RS15940
uniprot id: A0A142ES42
names: Similarity
messages: Belongs to the UPF0246 family.

1727163:AO498 RS00830
gene id: 1727163:AO498_RS00830
uniprot id: A0A142EIG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1727163:AO498 RS04355
gene id: 1727163:AO498_RS04355
uniprot id: A0A142EKH0
names: Similarity
messages: Belongs to the proline racemase family.

1727163:AO498 RS01675
gene id: 1727163:AO498_RS01675
uniprot id: A0A142EIX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1727163:AO498 RS12085
gene id: 1727163:AO498_RS12085
uniprot id: A0A142EPX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1727163:AO498 RS15870
gene id: 1727163:AO498_RS15870
uniprot id: A0A142ES28
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1727163:AO498 RS07765
gene id: 1727163:AO498_RS07765
uniprot id: A0A142EMF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1727163:AO498 RS05315
gene id: 1727163:AO498_RS05315
uniprot id: A0A142EL18
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1727163:AO498 RS12505
gene id: 1727163:AO498_RS12505
uniprot id: A0A142EQ56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1727163:AO498 RS08770
gene id: 1727163:AO498_RS08770
uniprot id: A0A142EN03
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS03715
gene id: 1727163:AO498_RS03715
uniprot id: A0A142EK41
names: Similarity
messages: Belongs to the LOG family.

1727163:AO498 RS03155
gene id: 1727163:AO498_RS03155
uniprot id: A0A142EJS5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1727163:AO498 RS01285
gene id: 1727163:AO498_RS01285
uniprot id: A0A142EIP9
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1727163:AO498 RS16550
gene id: 1727163:AO498_RS16550
uniprot id: A0A142ESF9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1727163:AO498 RS01320
gene id: 1727163:AO498_RS01320
uniprot id: A0A142EIQ6
names: Similarity
messages: Belongs to the AIR synthase family.

1727163:AO498 RS00120
gene id: 1727163:AO498_RS00120
uniprot id: A0A142EI22
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1727163:AO498 RS01590
gene id: 1727163:AO498_RS01590
uniprot id: A0A142EIW0
names: Similarity
messages: Belongs to the thioredoxin family.

1727163:AO498 RS15705
gene id: 1727163:AO498_RS15705
uniprot id: A0A142ERZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1727163:AO498 RS05490
gene id: 1727163:AO498_RS05490
uniprot id: A0A142EL49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1727163:AO498 RS05795
gene id: 1727163:AO498_RS05795
uniprot id: A0A142ELB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1727163:AO498 RS07615
gene id: 1727163:AO498_RS07615
uniprot id: A0A142EMC4
names: Similarity
messages: Belongs to the EPSP synthase family.

1727163:AO498 RS07995
gene id: 1727163:AO498_RS07995
uniprot id: A0A142EMJ9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1727163:AO498 RS13960
gene id: 1727163:AO498_RS13960
uniprot id: A0A142EQZ6
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS14925
gene id: 1727163:AO498_RS14925
uniprot id: A0A142ERJ1
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1727163:AO498 RS09940
gene id: 1727163:AO498_RS09940
uniprot id: A0A142ENP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1727163:AO498 RS08080
gene id: 1727163:AO498_RS08080
uniprot id: A0A142EML4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1727163:AO498 RS02065
gene id: 1727163:AO498_RS02065
uniprot id: A0A142EJ58
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1727163:AO498 RS06285
gene id: 1727163:AO498_RS06285
uniprot id: A0A142ELK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1727163:AO498 RS01265
gene id: 1727163:AO498_RS01265
uniprot id: A0A142EIP5
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1727163:AO498 RS04165
gene id: 1727163:AO498_RS04165
uniprot id: A0A142EKD2
names: Similarity
messages: Belongs to the aspartokinase family.

1727163:AO498 RS09930
gene id: 1727163:AO498_RS09930
uniprot id: A0A142ENN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1727163:AO498 RS08760
gene id: 1727163:AO498_RS08760
uniprot id: A0A142EN01
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS09280
gene id: 1727163:AO498_RS09280
uniprot id: A0A142ENA5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS04750
gene id: 1727163:AO498_RS04750
uniprot id: A0A142EKP9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1727163:AO498 RS00770
gene id: 1727163:AO498_RS00770
uniprot id: A0A142EIE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1727163:AO498 RS11910
gene id: 1727163:AO498_RS11910
uniprot id: A0A142EPT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1727163:AO498 RS06540
gene id: 1727163:AO498_RS06540
uniprot id: A0A142ELR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1727163:AO498 RS05470
gene id: 1727163:AO498_RS05470
uniprot id: A0A142EL45
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1727163:AO498 RS09725
gene id: 1727163:AO498_RS09725
uniprot id: A0A142ENJ6
names: Similarity
messages: Belongs to the peptidase U62 family.

1727163:AO498 RS01120
gene id: 1727163:AO498_RS01120
uniprot id: A0A142EIL5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1727163:AO498 RS16575
gene id: 1727163:AO498_RS16575
uniprot id: A0A142ESG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1727163:AO498 RS04200
gene id: 1727163:AO498_RS04200
uniprot id: A0A142EKD9
names: Similarity
messages: Belongs to the P(II) protein family.

1727163:AO498 RS15880
gene id: 1727163:AO498_RS15880
uniprot id: A0A142ES30
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS00730
gene id: 1727163:AO498_RS00730
uniprot id: A0A142EIE0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1727163:AO498 RS10705
gene id: 1727163:AO498_RS10705
uniprot id: A0A142EP44
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1727163:AO498 RS16580
gene id: 1727163:AO498_RS16580
uniprot id: A0A142ESG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1727163:AO498 RS05460
gene id: 1727163:AO498_RS05460
uniprot id: A0A142EL43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1727163:AO498 RS11370
gene id: 1727163:AO498_RS11370
uniprot id: A0A142EPI1
names: Similarity
messages: Belongs to the ribF family.

1727163:AO498 RS03145
gene id: 1727163:AO498_RS03145
uniprot id: A0A142EJS3
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS01855
gene id: 1727163:AO498_RS01855
uniprot id: A0A142EJ14
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS03790
gene id: 1727163:AO498_RS03790
uniprot id: A0A142EK56
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1727163:AO498 RS07510
gene id: 1727163:AO498_RS07510
uniprot id: A0A142EMA4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1727163:AO498 RS12715
gene id: 1727163:AO498_RS12715
uniprot id: A0A142EQ96
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1727163:AO498 RS16510
gene id: 1727163:AO498_RS16510
uniprot id: A0A142ESF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS14675
gene id: 1727163:AO498_RS14675
uniprot id: A0A142ERE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1727163:AO498 RS04825
gene id: 1727163:AO498_RS04825
uniprot id: A0A142EKR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1727163:AO498 RS16420
gene id: 1727163:AO498_RS16420
uniprot id: A0A142ESD5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1727163:AO498 RS11365
gene id: 1727163:AO498_RS11365
uniprot id: A0A142EPI0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1727163:AO498 RS12865
gene id: 1727163:AO498_RS12865
uniprot id: A0A142EQC6
names: Similarity
messages: Belongs to the CinA family.

1727163:AO498 RS08075
gene id: 1727163:AO498_RS08075
uniprot id: A0A142EML2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1727163:AO498 RS05510
gene id: 1727163:AO498_RS05510
uniprot id: A0A142EL53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1727163:AO498 RS05530
gene id: 1727163:AO498_RS05530
uniprot id: A0A142EL58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1727163:AO498 RS09145
gene id: 1727163:AO498_RS09145
uniprot id: A0A142EN78
names: Similarity
messages: Belongs to the glutamine synthetase family.

1727163:AO498 RS15020
gene id: 1727163:AO498_RS15020
uniprot id: A0A142ERL0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1727163:AO498 RS12420
gene id: 1727163:AO498_RS12420
uniprot id: A0A142EQ39
names: Similarity
messages: Belongs to the universal stress protein A family.

1727163:AO498 RS14620
gene id: 1727163:AO498_RS14620
uniprot id: A0A142ERC9
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS00505
gene id: 1727163:AO498_RS00505
uniprot id: A0A142EI95
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1727163:AO498 RS13870
gene id: 1727163:AO498_RS13870
uniprot id: A0A142EQX8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS13775
gene id: 1727163:AO498_RS13775
uniprot id: A0A142EQV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1727163:AO498 RS03465
gene id: 1727163:AO498_RS03465
uniprot id: A0A142EJY9
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

1727163:AO498 RS02775
gene id: 1727163:AO498_RS02775
uniprot id: A0A142EJJ9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1727163:AO498 RS12405
gene id: 1727163:AO498_RS12405
uniprot id: A0A142EQ36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1727163:AO498 RS10965
gene id: 1727163:AO498_RS10965
uniprot id: A0A142EP97
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1727163:AO498 RS04280
gene id: 1727163:AO498_RS04280
uniprot id: A0A142EKF6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1727163:AO498 RS00760
gene id: 1727163:AO498_RS00760
uniprot id: A0A142EIE6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1727163:AO498 RS06880
gene id: 1727163:AO498_RS06880
uniprot id: A0A142ELX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS16115
gene id: 1727163:AO498_RS16115
uniprot id: A0A142ES75
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1727163:AO498 RS05485
gene id: 1727163:AO498_RS05485
uniprot id: A0A142EL48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1727163:AO498 RS02485
gene id: 1727163:AO498_RS02485
uniprot id: A0A142EJE4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1727163:AO498 RS10000
gene id: 1727163:AO498_RS10000
uniprot id: A0A142ENQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS03340
gene id: 1727163:AO498_RS03340
uniprot id: A0A142EJW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1727163:AO498 RS04860
gene id: 1727163:AO498_RS04860
uniprot id: A0A142EKS1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1727163:AO498 RS02135
gene id: 1727163:AO498_RS02135
uniprot id: A0A142EJ72
names: Subcellular Location Annotation
messages: Membrane

1727163:AO498 RS04900
gene id: 1727163:AO498_RS04900
uniprot id: A0A142EKT0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.