1712654:A7C91 RS07470
gene id: 1712654:A7C91_RS07470
uniprot id: A0A172WHU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1712654:A7C91 RS03610
gene id: 1712654:A7C91_RS03610
uniprot id: A0A172WFY8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1712654:A7C91 RS09205
gene id: 1712654:A7C91_RS09205
uniprot id: A0A172WJ22
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1712654:A7C91 RS05340
gene id: 1712654:A7C91_RS05340
uniprot id: A0A172WH58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1712654:A7C91 RS00340
gene id: 1712654:A7C91_RS00340
uniprot id: A0A172WEH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1712654:A7C91 RS03225
gene id: 1712654:A7C91_RS03225
uniprot id: A0A172WG29
names: Similarity
messages: Belongs to the UPF0216 family.

1712654:A7C91 RS03500
gene id: 1712654:A7C91_RS03500
uniprot id: A0A172WFX9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1712654:A7C91 RS10450
gene id: 1712654:A7C91_RS10450
uniprot id: A0A172WJ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1712654:A7C91 RS05305
gene id: 1712654:A7C91_RS05305
uniprot id: A0A172WH02
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1712654:A7C91 RS09380
gene id: 1712654:A7C91_RS09380
uniprot id: A0A172WIY1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1712654:A7C91 RS00005
gene id: 1712654:A7C91_RS00005
uniprot id: A0A172WEE1
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.

1712654:A7C91 RS04465
gene id: 1712654:A7C91_RS04465
uniprot id: A0A172WGJ4
names: Similarity
messages: Belongs to the UPF0310 family.

1712654:A7C91 RS00545
gene id: 1712654:A7C91_RS00545
uniprot id: A0A172WER9
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS01900
gene id: 1712654:A7C91_RS01900
uniprot id: A0A172WFD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1712654:A7C91 RS08890
gene id: 1712654:A7C91_RS08890
uniprot id: A0A172WII0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS01285
gene id: 1712654:A7C91_RS01285
uniprot id: A0A172WF08
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

1712654:A7C91 RS03145
gene id: 1712654:A7C91_RS03145
uniprot id: A0A172WFS3
names: Similarity
messages: Belongs to the peptidase M20A family.

1712654:A7C91 RS00995
gene id: 1712654:A7C91_RS00995
uniprot id: A0A172WET2
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1712654:A7C91 RS07810
gene id: 1712654:A7C91_RS07810
uniprot id: A0A172WI38
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1712654:A7C91 RS06330
gene id: 1712654:A7C91_RS06330
uniprot id: A0A172WHB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1712654:A7C91 RS02960
gene id: 1712654:A7C91_RS02960
uniprot id: A0A172WFX4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1712654:A7C91 RS02280
gene id: 1712654:A7C91_RS02280
uniprot id: A0A172WFP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS08445
gene id: 1712654:A7C91_RS08445
uniprot id: A0A172WI97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1712654:A7C91 RS01035
gene id: 1712654:A7C91_RS01035
uniprot id: A0A172WEU0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

1712654:A7C91 RS10605
gene id: 1712654:A7C91_RS10605
uniprot id: A0A172WJC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1712654:A7C91 RS00425
gene id: 1712654:A7C91_RS00425
uniprot id: A0A172WEJ1
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS02800
gene id: 1712654:A7C91_RS02800
uniprot id: A0A172WFM0
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

1712654:A7C91 RS04890
gene id: 1712654:A7C91_RS04890
uniprot id: A0A172WGM1
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1712654:A7C91 RS03315
gene id: 1712654:A7C91_RS03315
uniprot id: A0A172WFU2
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1712654:A7C91 RS08665
gene id: 1712654:A7C91_RS08665
uniprot id: A0A172WID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

1712654:A7C91 RS09330
gene id: 1712654:A7C91_RS09330
uniprot id: A0A172WJ23
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

1712654:A7C91 RS08145
gene id: 1712654:A7C91_RS08145
uniprot id: A0A172WIA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

1712654:A7C91 RS04815
gene id: 1712654:A7C91_RS04815
uniprot id: A0A172WGK2
names: Similarity
messages: Belongs to the UPF0215 family.

1712654:A7C91 RS01515
gene id: 1712654:A7C91_RS01515
uniprot id: A0A172WF49
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS07075
gene id: 1712654:A7C91_RS07075
uniprot id: A0A172WHY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1712654:A7C91 RS04845
gene id: 1712654:A7C91_RS04845
uniprot id: A0A172WGI6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

1712654:A7C91 RS06375
gene id: 1712654:A7C91_RS06375
uniprot id: A0A172WHB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1712654:A7C91 RS06275
gene id: 1712654:A7C91_RS06275
uniprot id: A0A172WH87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1712654:A7C91 RS03890
gene id: 1712654:A7C91_RS03890
uniprot id: A0A172WGI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1712654:A7C91 RS09215
gene id: 1712654:A7C91_RS09215
uniprot id: A0A172WIN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

1712654:A7C91 RS03525
gene id: 1712654:A7C91_RS03525
uniprot id: A0A172WFY7
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS03950
gene id: 1712654:A7C91_RS03950
uniprot id: A0A172WGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1712654:A7C91 RS00710
gene id: 1712654:A7C91_RS00710
uniprot id: A0A172WEN0
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS01995
gene id: 1712654:A7C91_RS01995
uniprot id: A0A172WFJ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1712654:A7C91 RS02285
gene id: 1712654:A7C91_RS02285
uniprot id: A0A172WJV9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS04110
gene id: 1712654:A7C91_RS04110
uniprot id: A0A172WGF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1712654:A7C91 RS06925
gene id: 1712654:A7C91_RS06925
uniprot id: A0A172WHP6
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1712654:A7C91 RS05565
gene id: 1712654:A7C91_RS05565
uniprot id: A0A172WH22
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

1712654:A7C91 RS05105
gene id: 1712654:A7C91_RS05105
uniprot id: A0A172WH34
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1712654:A7C91 RS06400
gene id: 1712654:A7C91_RS06400
uniprot id: A0A172WHC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

1712654:A7C91 RS03260
gene id: 1712654:A7C91_RS03260
uniprot id: A0A172WG42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS04955
gene id: 1712654:A7C91_RS04955
uniprot id: A0A172WGK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

1712654:A7C91 RS04315
gene id: 1712654:A7C91_RS04315
uniprot id: A0A172WGB0
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS10030
gene id: 1712654:A7C91_RS10030
uniprot id: A0A172WJF8
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1712654:A7C91 RS04275
gene id: 1712654:A7C91_RS04275
uniprot id: A0A172WGP9
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS03430
gene id: 1712654:A7C91_RS03430
uniprot id: A0A172WFW0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1712654:A7C91 RS08610
gene id: 1712654:A7C91_RS08610
uniprot id: A0A172WIC4
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS09090
gene id: 1712654:A7C91_RS09090
uniprot id: A0A172WIT1
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

1712654:A7C91 RS03065
gene id: 1712654:A7C91_RS03065
uniprot id: A0A172WFR1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1712654:A7C91 RS09005
gene id: 1712654:A7C91_RS09005
uniprot id: A0A172WIK5
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS07480
gene id: 1712654:A7C91_RS07480
uniprot id: A0A172WIB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

1712654:A7C91 RS06990
gene id: 1712654:A7C91_RS06990
uniprot id: A0A172WHL3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS01600
gene id: 1712654:A7C91_RS01600
uniprot id: A0A172WJE7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

1712654:A7C91 RS08040
gene id: 1712654:A7C91_RS08040
uniprot id: A0A172WI86
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1712654:A7C91 RS03450
gene id: 1712654:A7C91_RS03450
uniprot id: A0A172WFX7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1712654:A7C91 RS06170
gene id: 1712654:A7C91_RS06170
uniprot id: A0A172WH85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

1712654:A7C91 RS02510
gene id: 1712654:A7C91_RS02510
uniprot id: A0A172WFJ7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1712654:A7C91 RS03595
gene id: 1712654:A7C91_RS03595
uniprot id: A0A172WG84
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

1712654:A7C91 RS06290
gene id: 1712654:A7C91_RS06290
uniprot id: A0A172WHM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

1712654:A7C91 RS01485
gene id: 1712654:A7C91_RS01485
uniprot id: A0A172WF02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1712654:A7C91 RS08000
gene id: 1712654:A7C91_RS08000
uniprot id: A0A172WI23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1712654:A7C91 RS06160
gene id: 1712654:A7C91_RS06160
uniprot id: A0A172WH80
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1712654:A7C91 RS04885
gene id: 1712654:A7C91_RS04885
uniprot id: A0A172WGR1
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1712654:A7C91 RS07260
gene id: 1712654:A7C91_RS07260
uniprot id: A0A172WHQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

1712654:A7C91 RS05640
gene id: 1712654:A7C91_RS05640
uniprot id: A0A172WJE9
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS01510
gene id: 1712654:A7C91_RS01510
uniprot id: A0A172WF03
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1712654:A7C91 RS07770
gene id: 1712654:A7C91_RS07770
uniprot id: A0A172WHY5
names: Similarity
messages: Belongs to the UPF0212 family.

1712654:A7C91 RS00205
gene id: 1712654:A7C91_RS00205
uniprot id: A0A172WEG0
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1712654:A7C91 RS07010
gene id: 1712654:A7C91_RS07010
uniprot id: A0A172WHM6
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS03415
gene id: 1712654:A7C91_RS03415
uniprot id: A0A172WFY4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1712654:A7C91 RS08885
gene id: 1712654:A7C91_RS08885
uniprot id: A0A172WIG4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1712654:A7C91 RS06155
gene id: 1712654:A7C91_RS06155
uniprot id: A0A172WHB8
names: Subcellular Location Annotation
messages: Nucleus

1712654:A7C91 RS05760
gene id: 1712654:A7C91_RS05760
uniprot id: A0A172WGZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1712654:A7C91 RS00440
gene id: 1712654:A7C91_RS00440
uniprot id: A0A172WEJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

1712654:A7C91 RS02260
gene id: 1712654:A7C91_RS02260
uniprot id: A0A172WFD8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS03730
gene id: 1712654:A7C91_RS03730
uniprot id: A0A172WG31
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS10180
gene id: 1712654:A7C91_RS10180
uniprot id: A0A172WJ46
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS01630
gene id: 1712654:A7C91_RS01630
uniprot id: A0A172WF24
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1712654:A7C91 RS07045
gene id: 1712654:A7C91_RS07045
uniprot id: A0A172WHM9
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1712654:A7C91 RS00875
gene id: 1712654:A7C91_RS00875
uniprot id: A0A172WEQ8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1712654:A7C91 RS07965
gene id: 1712654:A7C91_RS07965
uniprot id: A0A172WI28
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS06095
gene id: 1712654:A7C91_RS06095
uniprot id: A0A172WH60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

1712654:A7C91 RS05705
gene id: 1712654:A7C91_RS05705
uniprot id: A0A172WH08
names: Similarity
messages: Belongs to the UPF0145 family.

1712654:A7C91 RS02255
gene id: 1712654:A7C91_RS02255
uniprot id: A0A172WFF7
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS02515
gene id: 1712654:A7C91_RS02515
uniprot id: A0A172WFH7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1712654:A7C91 RS06920
gene id: 1712654:A7C91_RS06920
uniprot id: A0A172WHV3
names: Similarity
messages: Belongs to the HypE family.

1712654:A7C91 RS07740
gene id: 1712654:A7C91_RS07740
uniprot id: A0A172WI29
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

1712654:A7C91 RS07455
gene id: 1712654:A7C91_RS07455
uniprot id: A0A172WHT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

1712654:A7C91 RS04860
gene id: 1712654:A7C91_RS04860
uniprot id: A0A172WGT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1712654:A7C91 RS07230
gene id: 1712654:A7C91_RS07230
uniprot id: A0A172WI56
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS02505
gene id: 1712654:A7C91_RS02505
uniprot id: A0A172WFH0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1712654:A7C91 RS09560
gene id: 1712654:A7C91_RS09560
uniprot id: A0A172WIV0
names: Similarity
messages: Belongs to the UPF0284 family.

1712654:A7C91 RS06645
gene id: 1712654:A7C91_RS06645
uniprot id: A0A172WHY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

1712654:A7C91 RS04215
gene id: 1712654:A7C91_RS04215
uniprot id: A0A172WG98
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS07160
gene id: 1712654:A7C91_RS07160
uniprot id: A0A172WHP7
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS00775
gene id: 1712654:A7C91_RS00775
uniprot id: A0A172WEN9
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS04270
gene id: 1712654:A7C91_RS04270
uniprot id: A0A172WGI3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS08300
gene id: 1712654:A7C91_RS08300
uniprot id: A0A172WIE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1712654:A7C91 RS03240
gene id: 1712654:A7C91_RS03240
uniprot id: A0A172WFT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1712654:A7C91 RS05930
gene id: 1712654:A7C91_RS05930
uniprot id: A0A172WHB4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1712654:A7C91 RS03350
gene id: 1712654:A7C91_RS03350
uniprot id: A0A172WFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1712654:A7C91 RS08655
gene id: 1712654:A7C91_RS08655
uniprot id: A0A172WIF6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

1712654:A7C91 RS04630
gene id: 1712654:A7C91_RS04630
uniprot id: A0A172WGP4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1712654:A7C91 RS09825
gene id: 1712654:A7C91_RS09825
uniprot id: A0A172WJC6
names: Similarity
messages: Belongs to the HypE family.

1712654:A7C91 RS04580
gene id: 1712654:A7C91_RS04580
uniprot id: A0A172WGU8
names: Similarity
messages: Belongs to the UPF0147 family.

1712654:A7C91 RS04380
gene id: 1712654:A7C91_RS04380
uniprot id: A0A172WGC6
names: Similarity
messages: Belongs to the UPF0111 family.

1712654:A7C91 RS09980
gene id: 1712654:A7C91_RS09980
uniprot id: A0A172WJ65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

1712654:A7C91 RS08010
gene id: 1712654:A7C91_RS08010
uniprot id: A0A172WIK7
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1712654:A7C91 RS06615
gene id: 1712654:A7C91_RS06615
uniprot id: A0A172WHK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Cytoplasm

1712654:A7C91 RS02535
gene id: 1712654:A7C91_RS02535
uniprot id: A0A172WFS5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1712654:A7C91 RS09290
gene id: 1712654:A7C91_RS09290
uniprot id: A0A172WIN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

1712654:A7C91 RS07695
gene id: 1712654:A7C91_RS07695
uniprot id: A0A172WHW7
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

1712654:A7C91 RS06355
gene id: 1712654:A7C91_RS06355
uniprot id: A0A172WHB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1712654:A7C91 RS08935
gene id: 1712654:A7C91_RS08935
uniprot id: A0A172WIN7
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1712654:A7C91 RS09120
gene id: 1712654:A7C91_RS09120
uniprot id: A0A172WIL4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Potential transporter for phosphate.

1712654:A7C91 RS08575
gene id: 1712654:A7C91_RS08575
uniprot id: A0A172WIJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

1712654:A7C91 RS02685
gene id: 1712654:A7C91_RS02685
uniprot id: A0A172WFU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1712654:A7C91 RS06085
gene id: 1712654:A7C91_RS06085
uniprot id: A0A172WHJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

1712654:A7C91 RS01615
gene id: 1712654:A7C91_RS01615
uniprot id: A0A172WF32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1712654:A7C91 RS04455
gene id: 1712654:A7C91_RS04455
uniprot id: A0A172WGL7
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

1712654:A7C91 RS06285
gene id: 1712654:A7C91_RS06285
uniprot id: A0A172WHA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1712654:A7C91 RS02650
gene id: 1712654:A7C91_RS02650
uniprot id: A0A172WFJ3
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

1712654:A7C91 RS06350
gene id: 1712654:A7C91_RS06350
uniprot id: A0A172WHB9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

1712654:A7C91 RS03990
gene id: 1712654:A7C91_RS03990
uniprot id: A0A172WG50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS07805
gene id: 1712654:A7C91_RS07805
uniprot id: A0A172WIA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UppP family.
messages: Membrane

1712654:A7C91 RS05255
gene id: 1712654:A7C91_RS05255
uniprot id: A0A172WGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1712654:A7C91 RS00455
gene id: 1712654:A7C91_RS00455
uniprot id: A0A172WEJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1712654:A7C91 RS08455
gene id: 1712654:A7C91_RS08455
uniprot id: A0A172WIU1
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

1712654:A7C91 RS07905
gene id: 1712654:A7C91_RS07905
uniprot id: A0A172WIF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

1712654:A7C91 RS05490
gene id: 1712654:A7C91_RS05490
uniprot id: A0A172WH88
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

1712654:A7C91 RS07040
gene id: 1712654:A7C91_RS07040
uniprot id: A0A172WHM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1712654:A7C91 RS06195
gene id: 1712654:A7C91_RS06195
uniprot id: A0A172WH81
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1712654:A7C91 RS07720
gene id: 1712654:A7C91_RS07720
uniprot id: A0A172WHZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS08495
gene id: 1712654:A7C91_RS08495
uniprot id: A0A172WIC7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS00460
gene id: 1712654:A7C91_RS00460
uniprot id: A0A172WEJ2
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1712654:A7C91 RS01625
gene id: 1712654:A7C91_RS01625
uniprot id: A0A172WF87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

1712654:A7C91 RS01260
gene id: 1712654:A7C91_RS01260
uniprot id: A0A172WEW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

1712654:A7C91 RS07960
gene id: 1712654:A7C91_RS07960
uniprot id: A0A172WIG6
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the archaeal N-glycosylase/DNA lyase (AGOG) family.
messages: Contains two alpha-helical subdomains, with the 8-oxoguanine binding site located in a cleft at their interface. Contains a helix-hairpin-helix (HhH) structural motif and a Gly/Pro-rich sequence followed by a conserved Asp (HhH-GPD motif).
messages: DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS07185
gene id: 1712654:A7C91_RS07185
uniprot id: A0A172WI06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1712654:A7C91 RS07995
gene id: 1712654:A7C91_RS07995
uniprot id: A0A172WI17
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1712654:A7C91 RS01635
gene id: 1712654:A7C91_RS01635
uniprot id: A0A172WF47
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1712654:A7C91 RS09720
gene id: 1712654:A7C91_RS09720
uniprot id: A0A172WIW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1712654:A7C91 RS07915
gene id: 1712654:A7C91_RS07915
uniprot id: A0A172WI11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1712654:A7C91 RS07150
gene id: 1712654:A7C91_RS07150
uniprot id: A0A172WHN6
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS04640
gene id: 1712654:A7C91_RS04640
uniprot id: A0A172WGG9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

1712654:A7C91 RS03995
gene id: 1712654:A7C91_RS03995
uniprot id: A0A172WG64
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS08820
gene id: 1712654:A7C91_RS08820
uniprot id: A0A172WIL6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS07440
gene id: 1712654:A7C91_RS07440
uniprot id: A0A172WHX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

1712654:A7C91 RS06410
gene id: 1712654:A7C91_RS06410
uniprot id: A0A172WHN1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1712654:A7C91 RS07730
gene id: 1712654:A7C91_RS07730
uniprot id: A0A172WHY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1712654:A7C91 RS02175
gene id: 1712654:A7C91_RS02175
uniprot id: A0A172WFM2
names: Function
names: Subunit
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1712654:A7C91 RS05480
gene id: 1712654:A7C91_RS05480
uniprot id: A0A172WGW4
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.

1712654:A7C91 RS02630
gene id: 1712654:A7C91_RS02630
uniprot id: A0A172WFP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1712654:A7C91 RS10295
gene id: 1712654:A7C91_RS10295
uniprot id: A0A172WJ52
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

1712654:A7C91 RS06805
gene id: 1712654:A7C91_RS06805
uniprot id: A0A172WHJ1
names: Similarity
messages: Belongs to the UPF0252 family.

1712654:A7C91 RS04325
gene id: 1712654:A7C91_RS04325
uniprot id: A0A172WGB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1712654:A7C91 RS05465
gene id: 1712654:A7C91_RS05465
uniprot id: A0A172WH00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1712654:A7C91 RS04170
gene id: 1712654:A7C91_RS04170
uniprot id: A0A172WGM7
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS08120
gene id: 1712654:A7C91_RS08120
uniprot id: A0A172WIM6
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS04785
gene id: 1712654:A7C91_RS04785
uniprot id: A0A172WGJ3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

1712654:A7C91 RS08880
gene id: 1712654:A7C91_RS08880
uniprot id: A0A172WIK0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1712654:A7C91 RS05585
gene id: 1712654:A7C91_RS05585
uniprot id: A0A172WGY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1712654:A7C91 RS04030
gene id: 1712654:A7C91_RS04030
uniprot id: A0A172WGE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

1712654:A7C91 RS05535
gene id: 1712654:A7C91_RS05535
uniprot id: A0A172WGX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

1712654:A7C91 RS06320
gene id: 1712654:A7C91_RS06320
uniprot id: A0A172WHA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1712654:A7C91 RS04900
gene id: 1712654:A7C91_RS04900
uniprot id: A0A172WGL3
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1712654:A7C91 RS09925
gene id: 1712654:A7C91_RS09925
uniprot id: A0A172WJ18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1712654:A7C91 RS09615
gene id: 1712654:A7C91_RS09615
uniprot id: A0A172WJI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

1712654:A7C91 RS07055
gene id: 1712654:A7C91_RS07055
uniprot id: A0A172WI49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

1712654:A7C91 RS08910
gene id: 1712654:A7C91_RS08910
uniprot id: A0A172WJ17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1712654:A7C91 RS07475
gene id: 1712654:A7C91_RS07475
uniprot id: A0A172WJG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1712654:A7C91 RS06735
gene id: 1712654:A7C91_RS06735
uniprot id: A0A172WHL9
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

1712654:A7C91 RS04965
gene id: 1712654:A7C91_RS04965
uniprot id: A0A172WGM2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1712654:A7C91 RS10065
gene id: 1712654:A7C91_RS10065
uniprot id: A0A172WJ12
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1712654:A7C91 RS09235
gene id: 1712654:A7C91_RS09235
uniprot id: A0A172WIM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm

1712654:A7C91 RS07835
gene id: 1712654:A7C91_RS07835
uniprot id: A0A172WI03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1712654:A7C91 RS05995
gene id: 1712654:A7C91_RS05995
uniprot id: A0A172WH50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1712654:A7C91 RS03515
gene id: 1712654:A7C91_RS03515
uniprot id: A0A172WG83
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

1712654:A7C91 RS01075
gene id: 1712654:A7C91_RS01075
uniprot id: A0A172WEU2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1712654:A7C91 RS04250
gene id: 1712654:A7C91_RS04250
uniprot id: A0A172WGC2
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS05420
gene id: 1712654:A7C91_RS05420
uniprot id: A0A172WGW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1712654:A7C91 RS00540
gene id: 1712654:A7C91_RS00540
uniprot id: A0A172WEL8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1712654:A7C91 RS00700
gene id: 1712654:A7C91_RS00700
uniprot id: A0A172WJC8
names: Similarity
messages: Belongs to the UPF0252 family.

1712654:A7C91 RS00350
gene id: 1712654:A7C91_RS00350
uniprot id: A0A172WEJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

1712654:A7C91 RS06080
gene id: 1712654:A7C91_RS06080
uniprot id: A0A172WHI5
names: Similarity
messages: Belongs to the SDO1/SBDS family.

1712654:A7C91 RS10105
gene id: 1712654:A7C91_RS10105
uniprot id: A0A172WJE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

1712654:A7C91 RS00895
gene id: 1712654:A7C91_RS00895
uniprot id: A0A172WEQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1712654:A7C91 RS02165
gene id: 1712654:A7C91_RS02165
uniprot id: A0A172WFB8
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

1712654:A7C91 RS08105
gene id: 1712654:A7C91_RS08105
uniprot id: A0A172WI31
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1712654:A7C91 RS00780
gene id: 1712654:A7C91_RS00780
uniprot id: A0A172WES7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1712654:A7C91 RS09800
gene id: 1712654:A7C91_RS09800
uniprot id: A0A172WIW6
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS06385
gene id: 1712654:A7C91_RS06385
uniprot id: A0A172WHC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal adenylate kinase family.
messages: Cytoplasm

1712654:A7C91 RS03075
gene id: 1712654:A7C91_RS03075
uniprot id: A0A172WG10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1712654:A7C91 RS02690
gene id: 1712654:A7C91_RS02690
uniprot id: A0A172WFK1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1712654:A7C91 RS10275
gene id: 1712654:A7C91_RS10275
uniprot id: A0A172WJH5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-64 and Arg-67) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

1712654:A7C91 RS10595
gene id: 1712654:A7C91_RS10595
uniprot id: A0A172WJA3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1712654:A7C91 RS07140
gene id: 1712654:A7C91_RS07140
uniprot id: A0A172WHT2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1712654:A7C91 RS08570
gene id: 1712654:A7C91_RS08570
uniprot id: A0A172WIS3
names: Subunit
messages: Homotetramer.

1712654:A7C91 RS04245
gene id: 1712654:A7C91_RS04245
uniprot id: A0A172WGB7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS02100
gene id: 1712654:A7C91_RS02100
uniprot id: A0A172WFB2
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

1712654:A7C91 RS10305
gene id: 1712654:A7C91_RS10305
uniprot id: A0A172WJ75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

1712654:A7C91 RS03795
gene id: 1712654:A7C91_RS03795
uniprot id: A0A172WG40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

1712654:A7C91 RS08290
gene id: 1712654:A7C91_RS08290
uniprot id: A0A172WIQ8
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

1712654:A7C91 RS07285
gene id: 1712654:A7C91_RS07285
uniprot id: A0A172WHS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1712654:A7C91 RS03910
gene id: 1712654:A7C91_RS03910
uniprot id: A0A172WGD4
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

1712654:A7C91 RS00110
gene id: 1712654:A7C91_RS00110
uniprot id: A0A172WEH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1712654:A7C91 RS09625
gene id: 1712654:A7C91_RS09625
uniprot id: A0A172WJV3
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

1712654:A7C91 RS02425
gene id: 1712654:A7C91_RS02425
uniprot id: A0A172WFG1
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1712654:A7C91 RS07180
gene id: 1712654:A7C91_RS07180
uniprot id: A0A172WHQ0
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

1712654:A7C91 RS00975
gene id: 1712654:A7C91_RS00975
uniprot id: A0A172WEY5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1712654:A7C91 RS07600
gene id: 1712654:A7C91_RS07600
uniprot id: A0A172WHW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1712654:A7C91 RS05290
gene id: 1712654:A7C91_RS05290
uniprot id: A0A172WH64
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

1712654:A7C91 RS10615
gene id: 1712654:A7C91_RS10615
uniprot id: A0A172WJQ7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

1712654:A7C91 RS08055
gene id: 1712654:A7C91_RS08055
uniprot id: A0A172WI33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1712654:A7C91 RS00200
gene id: 1712654:A7C91_RS00200
uniprot id: A0A172WEH0
names: Similarity
messages: Belongs to the UPF0251 family.

1712654:A7C91 RS06705
gene id: 1712654:A7C91_RS06705
uniprot id: A0A172WHW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1712654:A7C91 RS10110
gene id: 1712654:A7C91_RS10110
uniprot id: A0A172WJ84
names: Similarity
messages: Belongs to the pyruvate kinase family.

1712654:A7C91 RS05910
gene id: 1712654:A7C91_RS05910
uniprot id: A0A172WH28
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1712654:A7C91 RS07315
gene id: 1712654:A7C91_RS07315
uniprot id: A0A172WHV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1712654:A7C91 RS06310
gene id: 1712654:A7C91_RS06310
uniprot id: A0A172WHJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1712654:A7C91 RS01770
gene id: 1712654:A7C91_RS01770
uniprot id: A0A172WFA2
names: Similarity
messages: Belongs to the peptidase S8 family.

1712654:A7C91 RS07685
gene id: 1712654:A7C91_RS07685
uniprot id: A0A172WI18
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.
messages: Belongs to the SIS family. PHI subfamily.

1712654:A7C91 RS04665
gene id: 1712654:A7C91_RS04665
uniprot id: A0A172WGI0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1712654:A7C91 RS02735
gene id: 1712654:A7C91_RS02735
uniprot id: A0A172WFV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1712654:A7C91 RS04600
gene id: 1712654:A7C91_RS04600
uniprot id: A0A172WGL4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1712654:A7C91 RS01360
gene id: 1712654:A7C91_RS01360
uniprot id: A0A172WEY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1712654:A7C91 RS09730
gene id: 1712654:A7C91_RS09730
uniprot id: A0A172WJ19
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1712654:A7C91 RS06370
gene id: 1712654:A7C91_RS06370
uniprot id: A0A172WHC1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1712654:A7C91 RS02470
gene id: 1712654:A7C91_RS02470
uniprot id: A0A172WFK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

1712654:A7C91 RS10520
gene id: 1712654:A7C91_RS10520
uniprot id: A0A172WJP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

1712654:A7C91 RS01275
gene id: 1712654:A7C91_RS01275
uniprot id: A0A172WEY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

1712654:A7C91 RS04575
gene id: 1712654:A7C91_RS04575
uniprot id: A0A172WGN4
names: Subunit
messages: Homotetramer.

1712654:A7C91 RS08950
gene id: 1712654:A7C91_RS08950
uniprot id: A0A172WII7
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1712654:A7C91 RS03230
gene id: 1712654:A7C91_RS03230
uniprot id: A0A172WFU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1712654:A7C91 RS00985
gene id: 1712654:A7C91_RS00985
uniprot id: A0A172WEV0
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS05010
gene id: 1712654:A7C91_RS05010
uniprot id: A0A172WGM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S16 family.
messages: Membrane

1712654:A7C91 RS06790
gene id: 1712654:A7C91_RS06790
uniprot id: A0A172WHT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1712654:A7C91 RS06760
gene id: 1712654:A7C91_RS06760
uniprot id: A0A172WHI3
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

1712654:A7C91 RS09860
gene id: 1712654:A7C91_RS09860
uniprot id: A0A172WIZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclic 2,3-diphosphoglycerate synthetase family.
messages: Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP.
messages: Cytoplasm

1712654:A7C91 RS03725
gene id: 1712654:A7C91_RS03725
uniprot id: A0A172WG26
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1712654:A7C91 RS02975
gene id: 1712654:A7C91_RS02975
uniprot id: A0A172WFQ6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1712654:A7C91 RS01520
gene id: 1712654:A7C91_RS01520
uniprot id: A0A172WF61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1712654:A7C91 RS10085
gene id: 1712654:A7C91_RS10085
uniprot id: A0A172WJJ9
names: Similarity
messages: Belongs to the UPF0045 family.

1712654:A7C91 RS07145
gene id: 1712654:A7C91_RS07145
uniprot id: A0A172WHQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1712654:A7C91 RS08985
gene id: 1712654:A7C91_RS08985
uniprot id: A0A172WIP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1712654:A7C91 RS00800
gene id: 1712654:A7C91_RS00800
uniprot id: A0A172WEQ4
names: Function
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
messages: Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.

1712654:A7C91 RS06655
gene id: 1712654:A7C91_RS06655
uniprot id: A0A172WHG4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1712654:A7C91 RS06725
gene id: 1712654:A7C91_RS06725
uniprot id: A0A172WHH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1712654:A7C91 RS05280
gene id: 1712654:A7C91_RS05280
uniprot id: A0A172WH48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Forms a Heterooligomeric complex of two stacked eight-membered rings.
messages: Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.

1712654:A7C91 RS05450
gene id: 1712654:A7C91_RS05450
uniprot id: A0A172WGV8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1712654:A7C91 RS06500
gene id: 1712654:A7C91_RS06500
uniprot id: A0A172WHE6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1712654:A7C91 RS07175
gene id: 1712654:A7C91_RS07175
uniprot id: A0A172WHQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-alpha family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1712654:A7C91 RS09700
gene id: 1712654:A7C91_RS09700
uniprot id: A0A172WIX3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1712654:A7C91 RS08875
gene id: 1712654:A7C91_RS08875
uniprot id: A0A172WIM9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1712654:A7C91 RS01440
gene id: 1712654:A7C91_RS01440
uniprot id: A0A172WF11
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1712654:A7C91 RS02180
gene id: 1712654:A7C91_RS02180
uniprot id: A0A172WFC5
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1712654:A7C91 RS02755
gene id: 1712654:A7C91_RS02755
uniprot id: A0A172WFL3
names: Similarity
messages: Belongs to the threonine synthase family.

1712654:A7C91 RS06510
gene id: 1712654:A7C91_RS06510
uniprot id: A0A172WHW6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

1712654:A7C91 RS07275
gene id: 1712654:A7C91_RS07275
uniprot id: A0A172WI87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

1712654:A7C91 RS06240
gene id: 1712654:A7C91_RS06240
uniprot id: A0A172WHM4
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1712654:A7C91 RS02715
gene id: 1712654:A7C91_RS02715
uniprot id: A0A172WJQ3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

1712654:A7C91 RS01030
gene id: 1712654:A7C91_RS01030
uniprot id: A0A172WEZ3
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

1712654:A7C91 RS04505
gene id: 1712654:A7C91_RS04505
uniprot id: A0A172WGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1712654:A7C91 RS00010
gene id: 1712654:A7C91_RS00010
uniprot id: A0A172WEC9
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

1712654:A7C91 RS04350
gene id: 1712654:A7C91_RS04350
uniprot id: A0A172WGK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

1712654:A7C91 RS01115
gene id: 1712654:A7C91_RS01115
uniprot id: A0A172WEU8
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

1712654:A7C91 RS06480
gene id: 1712654:A7C91_RS06480
uniprot id: A0A172WHE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1712654:A7C91 RS08700
gene id: 1712654:A7C91_RS08700
uniprot id: A0A172WIJ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Membrane

1712654:A7C91 RS01420
gene id: 1712654:A7C91_RS01420
uniprot id: A0A172WF55
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1712654:A7C91 RS10280
gene id: 1712654:A7C91_RS10280
uniprot id: A0A172WJB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS09695
gene id: 1712654:A7C91_RS09695
uniprot id: A0A172WIW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1712654:A7C91 RS03535
gene id: 1712654:A7C91_RS03535
uniprot id: A0A172WFZ1
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1712654:A7C91 RS03365
gene id: 1712654:A7C91_RS03365
uniprot id: A0A172WFV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

1712654:A7C91 RS02530
gene id: 1712654:A7C91_RS02530
uniprot id: A0A172WFL5
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS06265
gene id: 1712654:A7C91_RS06265
uniprot id: A0A172WHD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1712654:A7C91 RS09530
gene id: 1712654:A7C91_RS09530
uniprot id: A0A172WJ58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1712654:A7C91 RS05785
gene id: 1712654:A7C91_RS05785
uniprot id: A0A172WH10
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1712654:A7C91 RS07320
gene id: 1712654:A7C91_RS07320
uniprot id: A0A172WHT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1712654:A7C91 RS07405
gene id: 1712654:A7C91_RS07405
uniprot id: A0A172WIA4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1712654:A7C91 RS08025
gene id: 1712654:A7C91_RS08025
uniprot id: A0A172WI36
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

1712654:A7C91 RS06090
gene id: 1712654:A7C91_RS06090
uniprot id: A0A172WH62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

1712654:A7C91 RS08510
gene id: 1712654:A7C91_RS08510
uniprot id: A0A172WIC0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS07000
gene id: 1712654:A7C91_RS07000
uniprot id: A0A172WI40
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS10040
gene id: 1712654:A7C91_RS10040
uniprot id: A0A172WJ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

1712654:A7C91 RS06470
gene id: 1712654:A7C91_RS06470
uniprot id: A0A172WHP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1712654:A7C91 RS03680
gene id: 1712654:A7C91_RS03680
uniprot id: A0A172WFZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1712654:A7C91 RS04240
gene id: 1712654:A7C91_RS04240
uniprot id: A0A172WGH9
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS03265
gene id: 1712654:A7C91_RS03265
uniprot id: A0A172WFT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1712654:A7C91 RS04825
gene id: 1712654:A7C91_RS04825
uniprot id: A0A172WGT0
names: Similarity
messages: Belongs to the acylphosphatase family.

1712654:A7C91 RS03045
gene id: 1712654:A7C91_RS03045
uniprot id: A0A172WFR4
names: Similarity
messages: Belongs to the AOR/FOR family.

1712654:A7C91 RS03375
gene id: 1712654:A7C91_RS03375
uniprot id: A0A172WG62
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1712654:A7C91 RS05575
gene id: 1712654:A7C91_RS05575
uniprot id: A0A172WGW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

1712654:A7C91 RS08305
gene id: 1712654:A7C91_RS08305
uniprot id: A0A172WI80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1712654:A7C91 RS06325
gene id: 1712654:A7C91_RS06325
uniprot id: A0A172WH97
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1712654:A7C91 RS03685
gene id: 1712654:A7C91_RS03685
uniprot id: A0A172WG14
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1712654:A7C91 RS04225
gene id: 1712654:A7C91_RS04225
uniprot id: A0A172WGN7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS03445
gene id: 1712654:A7C91_RS03445
uniprot id: A0A172WFX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1712654:A7C91 RS10025
gene id: 1712654:A7C91_RS10025
uniprot id: A0A172WJJ1
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1712654:A7C91 RS09265
gene id: 1712654:A7C91_RS09265
uniprot id: A0A172WIW1
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS06965
gene id: 1712654:A7C91_RS06965
uniprot id: A0A172WHL4
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS02700
gene id: 1712654:A7C91_RS02700
uniprot id: A0A172WFM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homotetramer; although the tetramer contains four active sites, only two participate in the cleavage. Therefore, it should be considered as a dimer of dimers.

1712654:A7C91 RS06680
gene id: 1712654:A7C91_RS06680
uniprot id: A0A172WHG0
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS06710
gene id: 1712654:A7C91_RS06710
uniprot id: A0A172WHH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1712654:A7C91 RS08860
gene id: 1712654:A7C91_RS08860
uniprot id: A0A172WIP1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1712654:A7C91 RS08235
gene id: 1712654:A7C91_RS08235
uniprot id: A0A172WI77
names: Similarity
messages: Belongs to the AOR/FOR family.

1712654:A7C91 RS06205
gene id: 1712654:A7C91_RS06205
uniprot id: A0A172WHC4
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1712654:A7C91 RS05430
gene id: 1712654:A7C91_RS05430
uniprot id: A0A172WGV5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1712654:A7C91 RS02370
gene id: 1712654:A7C91_RS02370
uniprot id: A0A172WFK8
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS07840
gene id: 1712654:A7C91_RS07840
uniprot id: A0A172WIH6
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS07090
gene id: 1712654:A7C91_RS07090
uniprot id: A0A172WHM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1712654:A7C91 RS07535
gene id: 1712654:A7C91_RS07535
uniprot id: A0A172WIC3
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

1712654:A7C91 RS06815
gene id: 1712654:A7C91_RS06815
uniprot id: A0A172WHI6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1712654:A7C91 RS09410
gene id: 1712654:A7C91_RS09410
uniprot id: A0A172WIQ9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1712654:A7C91 RS09755
gene id: 1712654:A7C91_RS09755
uniprot id: A0A172WIY4
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS00230
gene id: 1712654:A7C91_RS00230
uniprot id: A0A172WEF3
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1712654:A7C91 RS05470
gene id: 1712654:A7C91_RS05470
uniprot id: A0A172WGX1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1712654:A7C91 RS08735
gene id: 1712654:A7C91_RS08735
uniprot id: A0A172WIM2
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1712654:A7C91 RS08280
gene id: 1712654:A7C91_RS08280
uniprot id: A0A172WI68
names: Similarity
messages: Belongs to the UPF0440 family.

1712654:A7C91 RS03735
gene id: 1712654:A7C91_RS03735
uniprot id: A0A172WG08
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS05800
gene id: 1712654:A7C91_RS05800
uniprot id: A0A172WH66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1712654:A7C91 RS06825
gene id: 1712654:A7C91_RS06825
uniprot id: A0A172WI13
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1712654:A7C91 RS03195
gene id: 1712654:A7C91_RS03195
uniprot id: A0A172WG12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

1712654:A7C91 RS07650
gene id: 1712654:A7C91_RS07650
uniprot id: A0A172WHW5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

1712654:A7C91 RS07485
gene id: 1712654:A7C91_RS07485
uniprot id: A0A172WI92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1712654:A7C91 RS06125
gene id: 1712654:A7C91_RS06125
uniprot id: A0A172WH74
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS06490
gene id: 1712654:A7C91_RS06490
uniprot id: A0A172WHD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1712654:A7C91 RS01905
gene id: 1712654:A7C91_RS01905
uniprot id: A0A172WF72
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS06075
gene id: 1712654:A7C91_RS06075
uniprot id: A0A172WH61
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1712654:A7C91 RS10325
gene id: 1712654:A7C91_RS10325
uniprot id: A0A172WJ68
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS06405
gene id: 1712654:A7C91_RS06405
uniprot id: A0A172WHC9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

1712654:A7C91 RS04255
gene id: 1712654:A7C91_RS04255
uniprot id: A0A172WGA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS04960
gene id: 1712654:A7C91_RS04960
uniprot id: A0A172WGM5
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1712654:A7C91 RS05860
gene id: 1712654:A7C91_RS05860
uniprot id: A0A172WHA2
names: Similarity
messages: Belongs to the DtxR/MntR family.

1712654:A7C91 RS00225
gene id: 1712654:A7C91_RS00225
uniprot id: A0A172WEJ3
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

1712654:A7C91 RS05870
gene id: 1712654:A7C91_RS05870
uniprot id: A0A172WH32
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS07505
gene id: 1712654:A7C91_RS07505
uniprot id: A0A172WHY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

1712654:A7C91 RS09665
gene id: 1712654:A7C91_RS09665
uniprot id: A0A172WJ76
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

1712654:A7C91 RS05150
gene id: 1712654:A7C91_RS05150
uniprot id: A0A172WGQ5
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS00625
gene id: 1712654:A7C91_RS00625
uniprot id: A0A172WJB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS08470
gene id: 1712654:A7C91_RS08470
uniprot id: A0A172WIH2
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS04125
gene id: 1712654:A7C91_RS04125
uniprot id: A0A172WG86
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1712654:A7C91 RS10320
gene id: 1712654:A7C91_RS10320
uniprot id: A0A172WJC0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1712654:A7C91 RS01500
gene id: 1712654:A7C91_RS01500
uniprot id: A0A172WF21
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1712654:A7C91 RS07170
gene id: 1712654:A7C91_RS07170
uniprot id: A0A172WI47
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

1712654:A7C91 RS02350
gene id: 1712654:A7C91_RS02350
uniprot id: A0A172WJS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

1712654:A7C91 RS04235
gene id: 1712654:A7C91_RS04235
uniprot id: A0A172WGA9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1712654:A7C91 RS03095
gene id: 1712654:A7C91_RS03095
uniprot id: A0A172WG09
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1712654:A7C91 RS06365
gene id: 1712654:A7C91_RS06365
uniprot id: A0A172WHG3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1712654:A7C91 RS10165
gene id: 1712654:A7C91_RS10165
uniprot id: A0A172WJ94
names: Similarity
messages: Belongs to the UPF0166 family.

1712654:A7C91 RS10580
gene id: 1712654:A7C91_RS10580
uniprot id: A0A172WJM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm

1712654:A7C91 RS02540
gene id: 1712654:A7C91_RS02540
uniprot id: A0A172WFI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

1712654:A7C91 RS02125
gene id: 1712654:A7C91_RS02125
uniprot id: A0A172WFB6
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

1712654:A7C91 RS02055
gene id: 1712654:A7C91_RS02055
uniprot id: A0A172WFD5
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS01730
gene id: 1712654:A7C91_RS01730
uniprot id: A0A172WF52
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1712654:A7C91 RS08140
gene id: 1712654:A7C91_RS08140
uniprot id: A0A172WIF9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1712654:A7C91 RS08045
gene id: 1712654:A7C91_RS08045
uniprot id: A0A172WI53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

1712654:A7C91 RS02355
gene id: 1712654:A7C91_RS02355
uniprot id: A0A172WFQ0
names: Similarity
messages: Belongs to the UPF0200 family.

1712654:A7C91 RS04205
gene id: 1712654:A7C91_RS04205
uniprot id: A0A172WG90
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS05445
gene id: 1712654:A7C91_RS05445
uniprot id: A0A172WH90
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS05545
gene id: 1712654:A7C91_RS05545
uniprot id: A0A172WHA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

1712654:A7C91 RS00125
gene id: 1712654:A7C91_RS00125
uniprot id: A0A172WEJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1712654:A7C91 RS09855
gene id: 1712654:A7C91_RS09855
uniprot id: A0A172WIX6
names: Function
names: Similarity
messages: Belongs to the 2-phosphoglycerate kinase family.
messages: Catalyzes the phosphorylation of 2-phosphoglycerate to 2,3-diphosphoglycerate. Involved in the biosynthesis of cyclic 2,3-bisphosphoglycerate, a thermoprotectant.

1712654:A7C91 RS00465
gene id: 1712654:A7C91_RS00465
uniprot id: A0A172WEM5
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS01680
gene id: 1712654:A7C91_RS01680
uniprot id: A0A172WF97
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1712654:A7C91 RS02590
gene id: 1712654:A7C91_RS02590
uniprot id: A0A172WFT2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS08615
gene id: 1712654:A7C91_RS08615
uniprot id: A0A172WID9
names: Similarity
messages: Belongs to the UPF0107 family.

1712654:A7C91 RS08150
gene id: 1712654:A7C91_RS08150
uniprot id: A0A172WI74
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS08085
gene id: 1712654:A7C91_RS08085
uniprot id: A0A172WI46
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1712654:A7C91 RS00665
gene id: 1712654:A7C91_RS00665
uniprot id: A0A172WET8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1712654:A7C91 RS05230
gene id: 1712654:A7C91_RS05230
uniprot id: A0A172WH53
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

1712654:A7C91 RS02020
gene id: 1712654:A7C91_RS02020
uniprot id: A0A172WFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1712654:A7C91 RS00060
gene id: 1712654:A7C91_RS00060
uniprot id: A0A172WEF0
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

1712654:A7C91 RS10010
gene id: 1712654:A7C91_RS10010
uniprot id: A0A172WJ00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1712654:A7C91 RS00290
gene id: 1712654:A7C91_RS00290
uniprot id: A0A172WEK2
names: Similarity
messages: Belongs to the UPF0248 family.

1712654:A7C91 RS07655
gene id: 1712654:A7C91_RS07655
uniprot id: A0A172WHX3
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1712654:A7C91 RS08325
gene id: 1712654:A7C91_RS08325
uniprot id: A0A172WI71
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS05455
gene id: 1712654:A7C91_RS05455
uniprot id: A0A172WGV4
names: Similarity
messages: Belongs to the GARS family.

1712654:A7C91 RS00880
gene id: 1712654:A7C91_RS00880
uniprot id: A0A172WES8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1712654:A7C91 RS03915
gene id: 1712654:A7C91_RS03915
uniprot id: A0A172WG57
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS00020
gene id: 1712654:A7C91_RS00020
uniprot id: A0A172WEC5
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

1712654:A7C91 RS06450
gene id: 1712654:A7C91_RS06450
uniprot id: A0A172WHR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

1712654:A7C91 RS08340
gene id: 1712654:A7C91_RS08340
uniprot id: A0A172WIR9
names: Similarity
messages: Belongs to the RuvB family.

1712654:A7C91 RS06695
gene id: 1712654:A7C91_RS06695
uniprot id: A0A172WHH4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

1712654:A7C91 RS09500
gene id: 1712654:A7C91_RS09500
uniprot id: A0A172WIT5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1712654:A7C91 RS04500
gene id: 1712654:A7C91_RS04500
uniprot id: A0A172WGM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS04735
gene id: 1712654:A7C91_RS04735
uniprot id: A0A172WGI5
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

1712654:A7C91 RS08690
gene id: 1712654:A7C91_RS08690
uniprot id: A0A172WIE9
names: Similarity
messages: Belongs to the RutC family.

1712654:A7C91 RS04230
gene id: 1712654:A7C91_RS04230
uniprot id: A0A172WGA6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS00360
gene id: 1712654:A7C91_RS00360
uniprot id: A0A172WEH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

1712654:A7C91 RS06465
gene id: 1712654:A7C91_RS06465
uniprot id: A0A172WHD9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

1712654:A7C91 RS09240
gene id: 1712654:A7C91_RS09240
uniprot id: A0A172WIN4
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

1712654:A7C91 RS01080
gene id: 1712654:A7C91_RS01080
uniprot id: A0A172WEW1
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1712654:A7C91 RS01525
gene id: 1712654:A7C91_RS01525
uniprot id: A0A172WF18
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

1712654:A7C91 RS06380
gene id: 1712654:A7C91_RS06380
uniprot id: A0A172WHC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1712654:A7C91 RS09315
gene id: 1712654:A7C91_RS09315
uniprot id: A0A172WJ44
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS00950
gene id: 1712654:A7C91_RS00950
uniprot id: A0A172WER6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1712654:A7C91 RS07570
gene id: 1712654:A7C91_RS07570
uniprot id: A0A172WHZ9
names: Similarity
messages: Belongs to the glutaredoxin family.

1712654:A7C91 RS09155
gene id: 1712654:A7C91_RS09155
uniprot id: A0A172WIU3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1712654:A7C91 RS06340
gene id: 1712654:A7C91_RS06340
uniprot id: A0A172WHP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

1712654:A7C91 RS05440
gene id: 1712654:A7C91_RS05440
uniprot id: A0A172WH78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1712654:A7C91 RS07110
gene id: 1712654:A7C91_RS07110
uniprot id: A0A172WI37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal-type GPI family.
messages: Cytoplasm
messages: Homodimer.

1712654:A7C91 RS07615
gene id: 1712654:A7C91_RS07615
uniprot id: A0A172WHX1
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1712654:A7C91 RS06280
gene id: 1712654:A7C91_RS06280
uniprot id: A0A172WHA5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1712654:A7C91 RS05040
gene id: 1712654:A7C91_RS05040
uniprot id: A0A172WGN2
names: Similarity
messages: Belongs to the peptidase U62 family.

1712654:A7C91 RS09270
gene id: 1712654:A7C91_RS09270
uniprot id: A0A172WIP4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

1712654:A7C91 RS05525
gene id: 1712654:A7C91_RS05525
uniprot id: A0A172WGV6
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS07945
gene id: 1712654:A7C91_RS07945
uniprot id: A0A172WI25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1712654:A7C91 RS09080
gene id: 1712654:A7C91_RS09080
uniprot id: A0A172WJ40
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1712654:A7C91 RS10160
gene id: 1712654:A7C91_RS10160
uniprot id: A0A172WJF3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1712654:A7C91 RS00565
gene id: 1712654:A7C91_RS00565
uniprot id: A0A172WEL6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1712654:A7C91 RS03020
gene id: 1712654:A7C91_RS03020
uniprot id: A0A172WJF7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

1712654:A7C91 RS06630
gene id: 1712654:A7C91_RS06630
uniprot id: A0A172WHF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

1712654:A7C91 RS06145
gene id: 1712654:A7C91_RS06145
uniprot id: A0A172WH69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

1712654:A7C91 RS06830
gene id: 1712654:A7C91_RS06830
uniprot id: A0A172WHY0
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS03805
gene id: 1712654:A7C91_RS03805
uniprot id: A0A172WG18
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS06415
gene id: 1712654:A7C91_RS06415
uniprot id: A0A172WHH6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1712654:A7C91 RS02720
gene id: 1712654:A7C91_RS02720
uniprot id: A0A172WFK4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

1712654:A7C91 RS06360
gene id: 1712654:A7C91_RS06360
uniprot id: A0A172WHL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1712654:A7C91 RS07550
gene id: 1712654:A7C91_RS07550
uniprot id: A0A172WIA1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1712654:A7C91 RS00680
gene id: 1712654:A7C91_RS00680
uniprot id: A0A172WEN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

1712654:A7C91 RS09125
gene id: 1712654:A7C91_RS09125
uniprot id: A0A172WIM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

1712654:A7C91 RS01375
gene id: 1712654:A7C91_RS01375
uniprot id: A0A172WEZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1712654:A7C91 RS04400
gene id: 1712654:A7C91_RS04400
uniprot id: A0A172WGD9
names: Similarity
messages: Belongs to the peptidase S9C family.

1712654:A7C91 RS06345
gene id: 1712654:A7C91_RS06345
uniprot id: A0A172WHQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1712654:A7C91 RS01265
gene id: 1712654:A7C91_RS01265
uniprot id: A0A172WEY9
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1712654:A7C91 RS02225
gene id: 1712654:A7C91_RS02225
uniprot id: A0A172WFN2
names: Subcellular Location Annotation
messages: Cell membrane

1712654:A7C91 RS04635
gene id: 1712654:A7C91_RS04635
uniprot id: A0A172WGV7
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS08295
gene id: 1712654:A7C91_RS08295
uniprot id: A0A172WIM3
names: Function
messages: Probably involved in the biogenesis of the ribosome.

1712654:A7C91 RS01445
gene id: 1712654:A7C91_RS01445
uniprot id: A0A172WEZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1712654:A7C91 RS05020
gene id: 1712654:A7C91_RS05020
uniprot id: A0A172WGT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS07445
gene id: 1712654:A7C91_RS07445
uniprot id: A0A172WHV0
names: Similarity
messages: Belongs to the UPF0292 family.

1712654:A7C91 RS05710
gene id: 1712654:A7C91_RS05710
uniprot id: A0A172WGY6
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

1712654:A7C91 RS02860
gene id: 1712654:A7C91_RS02860
uniprot id: A0A172WFN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1712654:A7C91 RS00815
gene id: 1712654:A7C91_RS00815
uniprot id: A0A172WES0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1712654:A7C91 RS07490
gene id: 1712654:A7C91_RS07490
uniprot id: A0A172WHU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

1712654:A7C91 RS00930
gene id: 1712654:A7C91_RS00930
uniprot id: A0A172WET6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1712654:A7C91 RS05270
gene id: 1712654:A7C91_RS05270
uniprot id: A0A172WGS4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

1712654:A7C91 RS06635
gene id: 1712654:A7C91_RS06635
uniprot id: A0A172WHF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
messages: Homodimer.

1712654:A7C91 RS10015
gene id: 1712654:A7C91_RS10015
uniprot id: A0A172WJ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1712654:A7C91 RS04545
gene id: 1712654:A7C91_RS04545
uniprot id: A0A172WGG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1712654:A7C91 RS05735
gene id: 1712654:A7C91_RS05735
uniprot id: A0A172WH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1712654:A7C91 RS10045
gene id: 1712654:A7C91_RS10045
uniprot id: A0A172WJD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1712654:A7C91 RS05425
gene id: 1712654:A7C91_RS05425
uniprot id: A0A172WGT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1712654:A7C91 RS01570
gene id: 1712654:A7C91_RS01570
uniprot id: A0A172WF17
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS04510
gene id: 1712654:A7C91_RS04510
uniprot id: A0A172WGF3
names: Similarity
messages: Belongs to the PstS family.

1712654:A7C91 RS04260
gene id: 1712654:A7C91_RS04260
uniprot id: A0A172WGB6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS04195
gene id: 1712654:A7C91_RS04195
uniprot id: A0A172WGA7
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS07575
gene id: 1712654:A7C91_RS07575
uniprot id: A0A172WHW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1712654:A7C91 RS02410
gene id: 1712654:A7C91_RS02410
uniprot id: A0A172WFJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

1712654:A7C91 RS01735
gene id: 1712654:A7C91_RS01735
uniprot id: A0A172WFA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1712654:A7C91 RS08100
gene id: 1712654:A7C91_RS08100
uniprot id: A0A172WI63
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS05560
gene id: 1712654:A7C91_RS05560
uniprot id: A0A172WH52
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

1712654:A7C91 RS08915
gene id: 1712654:A7C91_RS08915
uniprot id: A0A172WIX5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1712654:A7C91 RS07500
gene id: 1712654:A7C91_RS07500
uniprot id: A0A172WI52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1712654:A7C91 RS07400
gene id: 1712654:A7C91_RS07400
uniprot id: A0A172WJM0
names: Similarity
messages: Belongs to the thymidylate kinase family.

1712654:A7C91 RS03360
gene id: 1712654:A7C91_RS03360
uniprot id: A0A172WFV9
names: Function
messages: Part of a potassium transport system.

1712654:A7C91 RS01280
gene id: 1712654:A7C91_RS01280
uniprot id: A0A172WEW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Binds 2 Mg(2+) or Mn(2+) ions per subunit.
messages: Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
messages: Cell membrane

1712654:A7C91 RS06755
gene id: 1712654:A7C91_RS06755
uniprot id: A0A172WHH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1712654:A7C91 RS00495
gene id: 1712654:A7C91_RS00495
uniprot id: A0A172WEM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1712654:A7C91 RS08190
gene id: 1712654:A7C91_RS08190
uniprot id: A0A172WI62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1712654:A7C91 RS03590
gene id: 1712654:A7C91_RS03590
uniprot id: A0A172WJW9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1712654:A7C91 RS07990
gene id: 1712654:A7C91_RS07990
uniprot id: A0A172WI42
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1712654:A7C91 RS09710
gene id: 1712654:A7C91_RS09710
uniprot id: A0A172WJA7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1712654:A7C91 RS05085
gene id: 1712654:A7C91_RS05085
uniprot id: A0A172WGM6
names: Similarity
messages: Belongs to the BtpA family.

1712654:A7C91 RS03320
gene id: 1712654:A7C91_RS03320
uniprot id: A0A172WG30
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

1712654:A7C91 RS10585
gene id: 1712654:A7C91_RS10585
uniprot id: A0A172WJG5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1712654:A7C91 RS02450
gene id: 1712654:A7C91_RS02450
uniprot id: A0A172WFG6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1712654:A7C91 RS09505
gene id: 1712654:A7C91_RS09505
uniprot id: A0A172WJA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1712654:A7C91 RS01005
gene id: 1712654:A7C91_RS01005
uniprot id: A0A172WES5
names: Similarity
messages: Belongs to the PDCD5 family.

1712654:A7C91 RS01025
gene id: 1712654:A7C91_RS01025
uniprot id: A0A172WEV1
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

1712654:A7C91 RS09715
gene id: 1712654:A7C91_RS09715
uniprot id: A0A172WJ25
names: Function
names: Similarity
messages: Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
messages: Belongs to the archease family.

1712654:A7C91 RS00580
gene id: 1712654:A7C91_RS00580
uniprot id: A0A172WEQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

1712654:A7C91 RS00745
gene id: 1712654:A7C91_RS00745
uniprot id: A0A172WEN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1712654:A7C91 RS10330
gene id: 1712654:A7C91_RS10330
uniprot id: A0A172WJI4
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS09245
gene id: 1712654:A7C91_RS09245
uniprot id: A0A172WIP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

1712654:A7C91 RS02955
gene id: 1712654:A7C91_RS02955
uniprot id: A0A172WFP3
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS06390
gene id: 1712654:A7C91_RS06390
uniprot id: A0A172WHU6
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS01040
gene id: 1712654:A7C91_RS01040
uniprot id: A0A172WEV5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

1712654:A7C91 RS07625
gene id: 1712654:A7C91_RS07625
uniprot id: A0A172WI75
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1712654:A7C91 RS02525
gene id: 1712654:A7C91_RS02525
uniprot id: A0A172WFH4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1712654:A7C91 RS03280
gene id: 1712654:A7C91_RS03280
uniprot id: A0A172WG36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1712654:A7C91 RS04805
gene id: 1712654:A7C91_RS04805
uniprot id: A0A172WGS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1712654:A7C91 RS08845
gene id: 1712654:A7C91_RS08845
uniprot id: A0A172WIH5
names: Caution
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS04200
gene id: 1712654:A7C91_RS04200
uniprot id: A0A172WGB4
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS04970
gene id: 1712654:A7C91_RS04970
uniprot id: A0A172WGZ9
names: Similarity
messages: Belongs to the UPF0111 family.

1712654:A7C91 RS03925
gene id: 1712654:A7C91_RS03925
uniprot id: A0A172WG35
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

1712654:A7C91 RS08545
gene id: 1712654:A7C91_RS08545
uniprot id: A0A172WID7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1712654:A7C91 RS08225
gene id: 1712654:A7C91_RS08225
uniprot id: A0A172WI54
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1712654:A7C91 RS05475
gene id: 1712654:A7C91_RS05475
uniprot id: A0A172WGU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1712654:A7C91 RS06260
gene id: 1712654:A7C91_RS06260
uniprot id: A0A172WHH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

1712654:A7C91 RS03015
gene id: 1712654:A7C91_RS03015
uniprot id: A0A172WG02
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1712654:A7C91 RS09035
gene id: 1712654:A7C91_RS09035
uniprot id: A0A172WIW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

1712654:A7C91 RS04025
gene id: 1712654:A7C91_RS04025
uniprot id: A0A172WG66
names: Similarity
messages: Belongs to the GbsR family.

1712654:A7C91 RS03980
gene id: 1712654:A7C91_RS03980
uniprot id: A0A172WJK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer. Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.

1712654:A7C91 RS08755
gene id: 1712654:A7C91_RS08755
uniprot id: A0A172WIK6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1712654:A7C91 RS09485
gene id: 1712654:A7C91_RS09485
uniprot id: A0A172WJI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1712654:A7C91 RS00660
gene id: 1712654:A7C91_RS00660
uniprot id: A0A172WEN3
names: Similarity
messages: Belongs to the SfsA family.

1712654:A7C91 RS08490
gene id: 1712654:A7C91_RS08490
uniprot id: A0A172WIG1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS07430
gene id: 1712654:A7C91_RS07430
uniprot id: A0A172WHT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

1712654:A7C91 RS03550
gene id: 1712654:A7C91_RS03550
uniprot id: A0A172WFZ3
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1712654:A7C91 RS02655
gene id: 1712654:A7C91_RS02655
uniprot id: A0A172WFJ6
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

1712654:A7C91 RS08865
gene id: 1712654:A7C91_RS08865
uniprot id: A0A172WIH8
names: Similarity
messages: Belongs to the NodU/CmcH family.

1712654:A7C91 RS02550
gene id: 1712654:A7C91_RS02550
uniprot id: A0A172WFN6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1712654:A7C91 RS07885
gene id: 1712654:A7C91_RS07885
uniprot id: A0A172WI05
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS04590
gene id: 1712654:A7C91_RS04590
uniprot id: A0A172WGG3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1712654:A7C91 RS07255
gene id: 1712654:A7C91_RS07255
uniprot id: A0A172WHS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

1712654:A7C91 RS02110
gene id: 1712654:A7C91_RS02110
uniprot id: A0A172WFB0
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

1712654:A7C91 RS00370
gene id: 1712654:A7C91_RS00370
uniprot id: A0A172WEN1
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

1712654:A7C91 RS09870
gene id: 1712654:A7C91_RS09870
uniprot id: A0A172WJ04
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1712654:A7C91 RS04080
gene id: 1712654:A7C91_RS04080
uniprot id: A0A172WGF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1712654:A7C91 RS10610
gene id: 1712654:A7C91_RS10610
uniprot id: A0A172WJT9
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1712654:A7C91 RS08565
gene id: 1712654:A7C91_RS08565
uniprot id: A0A172WIW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1712654:A7C91 RS02440
gene id: 1712654:A7C91_RS02440
uniprot id: A0A172WFG2
names: Similarity
messages: Belongs to the UPF0282 family.

1712654:A7C91 RS04915
gene id: 1712654:A7C91_RS04915
uniprot id: A0A172WGU6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Potential transporter for phosphate.

1712654:A7C91 RS03200
gene id: 1712654:A7C91_RS03200
uniprot id: A0A172WG32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1712654:A7C91 RS10195
gene id: 1712654:A7C91_RS10195
uniprot id: A0A172WJI8
names: Similarity
messages: Belongs to the peptidase U62 family.

1712654:A7C91 RS05765
gene id: 1712654:A7C91_RS05765
uniprot id: A0A172WH12
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1712654:A7C91 RS06270
gene id: 1712654:A7C91_RS06270
uniprot id: A0A172WH98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

1712654:A7C91 RS07585
gene id: 1712654:A7C91_RS07585
uniprot id: A0A172WHU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1712654:A7C91 RS06475
gene id: 1712654:A7C91_RS06475
uniprot id: A0A172WHI4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1712654:A7C91 RS07680
gene id: 1712654:A7C91_RS07680
uniprot id: A0A172WI84
names: Similarity
messages: Belongs to the arginase family.

1712654:A7C91 RS05875
gene id: 1712654:A7C91_RS05875
uniprot id: A0A172WH17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1712654:A7C91 RS08965
gene id: 1712654:A7C91_RS08965
uniprot id: A0A172WIY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1712654:A7C91 RS09765
gene id: 1712654:A7C91_RS09765
uniprot id: A0A172WJB7
names: Similarity
messages: Belongs to the IMPACT family.

1712654:A7C91 RS07105
gene id: 1712654:A7C91_RS07105
uniprot id: A0A172WI60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS08390
gene id: 1712654:A7C91_RS08390
uniprot id: A0A172WIA3
names: Similarity
messages: Belongs to the glutaredoxin family.

1712654:A7C91 RS05980
gene id: 1712654:A7C91_RS05980
uniprot id: A0A172WH38
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1712654:A7C91 RS02190
gene id: 1712654:A7C91_RS02190
uniprot id: A0A172WFH9
names: Similarity
messages: Belongs to the UPF0173 family.

1712654:A7C91 RS04835
gene id: 1712654:A7C91_RS04835
uniprot id: A0A172WGK9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1712654:A7C91 RS02365
gene id: 1712654:A7C91_RS02365
uniprot id: A0A172WFF9
names: Similarity
messages: Belongs to the UPF0201 family.

1712654:A7C91 RS03340
gene id: 1712654:A7C91_RS03340
uniprot id: A0A172WG45
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1712654:A7C91 RS04655
gene id: 1712654:A7C91_RS04655
uniprot id: A0A172WGP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1712654:A7C91 RS08285
gene id: 1712654:A7C91_RS08285
uniprot id: A0A172WI85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1712654:A7C91 RS03385
gene id: 1712654:A7C91_RS03385
uniprot id: A0A172WFW7
names: Similarity
messages: Belongs to the UPF0273 family.

1712654:A7C91 RS08185
gene id: 1712654:A7C91_RS08185
uniprot id: A0A172WI69
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS07270
gene id: 1712654:A7C91_RS07270
uniprot id: A0A172WHR1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

1712654:A7C91 RS00730
gene id: 1712654:A7C91_RS00730
uniprot id: A0A172WEN8
names: Similarity
messages: Belongs to the UPF0179 family.

1712654:A7C91 RS00025
gene id: 1712654:A7C91_RS00025
uniprot id: A0A172WEB2
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

1712654:A7C91 RS05795
gene id: 1712654:A7C91_RS05795
uniprot id: A0A172WH89
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

1712654:A7C91 RS07985
gene id: 1712654:A7C91_RS07985
uniprot id: A0A172WI76
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS05555
gene id: 1712654:A7C91_RS05555
uniprot id: A0A172WGX0
names: Similarity
messages: Belongs to the peptidase S8 family.

1712654:A7C91 RS01610
gene id: 1712654:A7C91_RS01610
uniprot id: A0A172WF28
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1712654:A7C91 RS07845
gene id: 1712654:A7C91_RS07845
uniprot id: A0A172WIE6
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1712654:A7C91 RS06440
gene id: 1712654:A7C91_RS06440
uniprot id: A0A172WHD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1712654:A7C91 RS10095
gene id: 1712654:A7C91_RS10095
uniprot id: A0A172WJ82
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1712654:A7C91 RS09880
gene id: 1712654:A7C91_RS09880
uniprot id: A0A172WJH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

1712654:A7C91 RS10265
gene id: 1712654:A7C91_RS10265
uniprot id: A0A172WJB0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

1712654:A7C91 RS01530
gene id: 1712654:A7C91_RS01530
uniprot id: A0A172WF22
names: Subunit
messages: Homodimer.

1712654:A7C91 RS06395
gene id: 1712654:A7C91_RS06395
uniprot id: A0A172WHR0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

1712654:A7C91 RS08035
gene id: 1712654:A7C91_RS08035
uniprot id: A0A172WID8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

1712654:A7C91 RS06315
gene id: 1712654:A7C91_RS06315
uniprot id: A0A172WHE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

1712654:A7C91 RS03875
gene id: 1712654:A7C91_RS03875
uniprot id: A0A172WG33
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS08155
gene id: 1712654:A7C91_RS08155
uniprot id: A0A172WI44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

1712654:A7C91 RS04780
gene id: 1712654:A7C91_RS04780
uniprot id: A0A172WGH6
names: Similarity
messages: Belongs to the AOR/FOR family.

1712654:A7C91 RS06520
gene id: 1712654:A7C91_RS06520
uniprot id: A0A172WHE8
names: Similarity
messages: Belongs to the FUN14 family.

1712654:A7C91 RS00910
gene id: 1712654:A7C91_RS00910
uniprot id: A0A172WER7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1712654:A7C91 RS05730
gene id: 1712654:A7C91_RS05730
uniprot id: A0A172WHD6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1712654:A7C91 RS09275
gene id: 1712654:A7C91_RS09275
uniprot id: A0A172WJ08
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

1712654:A7C91 RS10525
gene id: 1712654:A7C91_RS10525
uniprot id: A0A172WJL2
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1712654:A7C91 RS06690
gene id: 1712654:A7C91_RS06690
uniprot id: A0A172WHG9
names: Similarity
messages: Belongs to the peptidase M24B family.

1712654:A7C91 RS09225
gene id: 1712654:A7C91_RS09225
uniprot id: A0A172WIT9
names: Similarity
messages: Belongs to the UPF0235 family.

1712654:A7C91 RS03345
gene id: 1712654:A7C91_RS03345
uniprot id: A0A172WFW4
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS03930
gene id: 1712654:A7C91_RS03930
uniprot id: A0A172WG53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

1712654:A7C91 RS02710
gene id: 1712654:A7C91_RS02710
uniprot id: A0A172WFK6
names: Similarity
messages: Belongs to the HerA family.

1712654:A7C91 RS00030
gene id: 1712654:A7C91_RS00030
uniprot id: A0A172WEE9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

1712654:A7C91 RS09335
gene id: 1712654:A7C91_RS09335
uniprot id: A0A172WIV9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS04910
gene id: 1712654:A7C91_RS04910
uniprot id: A0A172WJX9
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1712654:A7C91 RS02270
gene id: 1712654:A7C91_RS02270
uniprot id: A0A172WFD7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS07265
gene id: 1712654:A7C91_RS07265
uniprot id: A0A172WHQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

1712654:A7C91 RS07345
gene id: 1712654:A7C91_RS07345
uniprot id: A0A172WI96
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS05580
gene id: 1712654:A7C91_RS05580
uniprot id: A0A172WGY2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

1712654:A7C91 RS06295
gene id: 1712654:A7C91_RS06295
uniprot id: A0A172WHN5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1712654:A7C91 RS09920
gene id: 1712654:A7C91_RS09920
uniprot id: A0A172WJ49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1712654:A7C91 RS06865
gene id: 1712654:A7C91_RS06865
uniprot id: A0A172WHI9
names: Similarity
messages: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.

1712654:A7C91 RS09450
gene id: 1712654:A7C91_RS09450
uniprot id: A0A172WJ41
names: Similarity
messages: Belongs to the peptidase U62 family.

1712654:A7C91 RS04045
gene id: 1712654:A7C91_RS04045
uniprot id: A0A172WG60
names: Similarity
messages: Belongs to the MoaD family.

1712654:A7C91 RS02045
gene id: 1712654:A7C91_RS02045
uniprot id: A0A172WFA4
names: Similarity
messages: Belongs to the peptidase C56 family.

1712654:A7C91 RS04645
gene id: 1712654:A7C91_RS04645
uniprot id: A0A172WJG6
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

1712654:A7C91 RS02805
gene id: 1712654:A7C91_RS02805
uniprot id: A0A172WFM9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1712654:A7C91 RS04905
gene id: 1712654:A7C91_RS04905
uniprot id: A0A172WGK7
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1712654:A7C91 RS07775
gene id: 1712654:A7C91_RS07775
uniprot id: A0A172WHZ3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS04000
gene id: 1712654:A7C91_RS04000
uniprot id: A0A172WG59
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs.

1712654:A7C91 RS08485
gene id: 1712654:A7C91_RS08485
uniprot id: A0A172WIM1
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS06930
gene id: 1712654:A7C91_RS06930
uniprot id: A0A172WHK9
names: Similarity
messages: Belongs to the HypD family.

1712654:A7C91 RS06565
gene id: 1712654:A7C91_RS06565
uniprot id: A0A172WHF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1712654:A7C91 RS04975
gene id: 1712654:A7C91_RS04975
uniprot id: A0A172WH15
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1712654:A7C91 RS05865
gene id: 1712654:A7C91_RS05865
uniprot id: A0A172WH76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS08925
gene id: 1712654:A7C91_RS08925
uniprot id: A0A172WIJ0
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1712654:A7C91 RS02090
gene id: 1712654:A7C91_RS02090
uniprot id: A0A172WFC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS09070
gene id: 1712654:A7C91_RS09070
uniprot id: A0A172WIL5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS07015
gene id: 1712654:A7C91_RS07015
uniprot id: A0A172WHM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS00325
gene id: 1712654:A7C91_RS00325
uniprot id: A0A172WEG4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1712654:A7C91 RS07415
gene id: 1712654:A7C91_RS07415
uniprot id: A0A172WI83
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS06585
gene id: 1712654:A7C91_RS06585
uniprot id: A0A172WHU0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

1712654:A7C91 RS02330
gene id: 1712654:A7C91_RS02330
uniprot id: A0A172WFE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1712654:A7C91 RS03935
gene id: 1712654:A7C91_RS03935
uniprot id: A0A172WG49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

1712654:A7C91 RS09570
gene id: 1712654:A7C91_RS09570
uniprot id: A0A172WJ81
names: Similarity
messages: Belongs to the MoaB/Mog family.

1712654:A7C91 RS09935
gene id: 1712654:A7C91_RS09935
uniprot id: A0A172WIY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1712654:A7C91 RS00330
gene id: 1712654:A7C91_RS00330
uniprot id: A0A172WEI6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

1712654:A7C91 RS00515
gene id: 1712654:A7C91_RS00515
uniprot id: A0A172WEN5
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS03650
gene id: 1712654:A7C91_RS03650
uniprot id: A0A172WG06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1712654:A7C91 RS02115
gene id: 1712654:A7C91_RS02115
uniprot id: A0A172WFE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

1712654:A7C91 RS01940
gene id: 1712654:A7C91_RS01940
uniprot id: A0A172WFB7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS07555
gene id: 1712654:A7C91_RS07555
uniprot id: A0A172WHW1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
messages: Binds 1 FAD per subunit.
messages: Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
messages: Reduction reaction proceeds via syn addition of hydrogen for double bonds.

1712654:A7C91 RS05900
gene id: 1712654:A7C91_RS05900
uniprot id: A0A172WHG6
names: Similarity
messages: Belongs to the UPF0045 family.

1712654:A7C91 RS00990
gene id: 1712654:A7C91_RS00990
uniprot id: A0A172WET3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

1712654:A7C91 RS01010
gene id: 1712654:A7C91_RS01010
uniprot id: A0A172WEW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

1712654:A7C91 RS07900
gene id: 1712654:A7C91_RS07900
uniprot id: A0A172WII5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS03120
gene id: 1712654:A7C91_RS03120
uniprot id: A0A172WFR8
names: Similarity
messages: Belongs to the UPF0146 family.

1712654:A7C91 RS04095
gene id: 1712654:A7C91_RS04095
uniprot id: A0A172WG70
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1712654:A7C91 RS07290
gene id: 1712654:A7C91_RS07290
uniprot id: A0A172WHR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1712654:A7C91 RS09885
gene id: 1712654:A7C91_RS09885
uniprot id: A0A172WJK3
names: Similarity
messages: Belongs to the AOR/FOR family.

1712654:A7C91 RS07370
gene id: 1712654:A7C91_RS07370
uniprot id: A0A172WI34
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1712654:A7C91 RS04750
gene id: 1712654:A7C91_RS04750
uniprot id: A0A172WGX5
names: Similarity
messages: Belongs to the carbamate kinase family.

1712654:A7C91 RS02775
gene id: 1712654:A7C91_RS02775
uniprot id: A0A172WFL6
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS01700
gene id: 1712654:A7C91_RS01700
uniprot id: A0A172WF43
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS04550
gene id: 1712654:A7C91_RS04550
uniprot id: A0A172WGE8
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS08835
gene id: 1712654:A7C91_RS08835
uniprot id: A0A172WIH0
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

1712654:A7C91 RS01370
gene id: 1712654:A7C91_RS01370
uniprot id: A0A172WF06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1712654:A7C91 RS10185
gene id: 1712654:A7C91_RS10185
uniprot id: A0A172WJ57
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1712654:A7C91 RS06770
gene id: 1712654:A7C91_RS06770
uniprot id: A0A172WHW9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1712654:A7C91 RS08640
gene id: 1712654:A7C91_RS08640
uniprot id: A0A172WIE0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

1712654:A7C91 RS01715
gene id: 1712654:A7C91_RS01715
uniprot id: A0A172WF78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1712654:A7C91 RS06105
gene id: 1712654:A7C91_RS06105
uniprot id: A0A172WHB0
names: Similarity
messages: Belongs to the ZPR1 family.

1712654:A7C91 RS02680
gene id: 1712654:A7C91_RS02680
uniprot id: A0A172WFK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1712654:A7C91 RS00050
gene id: 1712654:A7C91_RS00050
uniprot id: A0A172WEI9
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS06335
gene id: 1712654:A7C91_RS06335
uniprot id: A0A172WHB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

1712654:A7C91 RS10375
gene id: 1712654:A7C91_RS10375
uniprot id: A0A172WJ73
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS06230
gene id: 1712654:A7C91_RS06230
uniprot id: A0A172WH94
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1712654:A7C91 RS07785
gene id: 1712654:A7C91_RS07785
uniprot id: A0A172WID5
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

1712654:A7C91 RS07495
gene id: 1712654:A7C91_RS07495
uniprot id: A0A172WHU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

1712654:A7C91 RS06935
gene id: 1712654:A7C91_RS06935
uniprot id: A0A172WHJ9
names: Similarity
messages: Belongs to the HupF/HypC family.

1712654:A7C91 RS03335
gene id: 1712654:A7C91_RS03335
uniprot id: A0A172WFV7
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1712654:A7C91 RS09555
gene id: 1712654:A7C91_RS09555
uniprot id: A0A172WIT8
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1712654:A7C91 RS07865
gene id: 1712654:A7C91_RS07865
uniprot id: A0A172WIA9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1712654:A7C91 RS00650
gene id: 1712654:A7C91_RS00650
uniprot id: A0A172WES1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerA subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1712654:A7C91 RS01325
gene id: 1712654:A7C91_RS01325
uniprot id: A0A172WEZ1
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS07735
gene id: 1712654:A7C91_RS07735
uniprot id: A0A172WI93
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1712654:A7C91 RS06625
gene id: 1712654:A7C91_RS06625
uniprot id: A0A172WHG1
names: Similarity
messages: Belongs to the MEMO1 family.

1712654:A7C91 RS00725
gene id: 1712654:A7C91_RS00725
uniprot id: A0A172WET0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

1712654:A7C91 RS07030
gene id: 1712654:A7C91_RS07030
uniprot id: A0A172WHN0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1712654:A7C91 RS06960
gene id: 1712654:A7C91_RS06960
uniprot id: A0A172WHL6
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS00355
gene id: 1712654:A7C91_RS00355
uniprot id: A0A172WEL0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

1712654:A7C91 RS01545
gene id: 1712654:A7C91_RS01545
uniprot id: A0A172WF36
names: Similarity
messages: Belongs to the UPF0047 family.

1712654:A7C91 RS02790
gene id: 1712654:A7C91_RS02790
uniprot id: A0A172WFU5
names: Similarity
messages: Belongs to the UPF0047 family.

1712654:A7C91 RS06495
gene id: 1712654:A7C91_RS06495
uniprot id: A0A172WHE1
names: Similarity
messages: Belongs to the enolase family.

1712654:A7C91 RS02745
gene id: 1712654:A7C91_RS02745
uniprot id: A0A172WFL9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1712654:A7C91 RS09010
gene id: 1712654:A7C91_RS09010
uniprot id: A0A172WJ37
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS03135
gene id: 1712654:A7C91_RS03135
uniprot id: A0A172WG00
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS07935
gene id: 1712654:A7C91_RS07935
uniprot id: A0A172WI07
names: Similarity
messages: Belongs to the peptidase S49 family.

1712654:A7C91 RS05360
gene id: 1712654:A7C91_RS05360
uniprot id: A0A172WH13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

1712654:A7C91 RS05775
gene id: 1712654:A7C91_RS05775
uniprot id: A0A172WHD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

1712654:A7C91 RS04920
gene id: 1712654:A7C91_RS04920
uniprot id: A0A172WH06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1712654:A7C91 RS04820
gene id: 1712654:A7C91_RS04820
uniprot id: A0A172WGK0
names: Similarity
messages: Belongs to the CutA family.

1712654:A7C91 RS08505
gene id: 1712654:A7C91_RS08505
uniprot id: A0A172WIA5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS03960
gene id: 1712654:A7C91_RS03960
uniprot id: A0A172WG56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1712654:A7C91 RS10435
gene id: 1712654:A7C91_RS10435
uniprot id: A0A172WJQ9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1712654:A7C91 RS03330
gene id: 1712654:A7C91_RS03330
uniprot id: A0A172WFV0
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1712654:A7C91 RS00865
gene id: 1712654:A7C91_RS00865
uniprot id: A0A172WER4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1712654:A7C91 RS02230
gene id: 1712654:A7C91_RS02230
uniprot id: A0A172WFD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1712654:A7C91 RS00210
gene id: 1712654:A7C91_RS00210
uniprot id: A0A172WEF4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

1712654:A7C91 RS08200
gene id: 1712654:A7C91_RS08200
uniprot id: A0A172WIG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1712654:A7C91 RS09655
gene id: 1712654:A7C91_RS09655
uniprot id: A0A172WJ16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Forms a Heterooligomeric complex of two stacked eight-membered rings.
messages: Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.

1712654:A7C91 RS10070
gene id: 1712654:A7C91_RS10070
uniprot id: A0A172WJ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1712654:A7C91 RS03370
gene id: 1712654:A7C91_RS03370
uniprot id: A0A172WG38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

1712654:A7C91 RS08850
gene id: 1712654:A7C91_RS08850
uniprot id: A0A172WJ06
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1712654:A7C91 RS02315
gene id: 1712654:A7C91_RS02315
uniprot id: A0A172WFG8
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1712654:A7C91 RS06675
gene id: 1712654:A7C91_RS06675
uniprot id: A0A172WHH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1712654:A7C91 RS03785
gene id: 1712654:A7C91_RS03785
uniprot id: A0A172WG27
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS10600
gene id: 1712654:A7C91_RS10600
uniprot id: A0A172WJB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1712654:A7C91 RS07280
gene id: 1712654:A7C91_RS07280
uniprot id: A0A172WI64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1712654:A7C91 RS05185
gene id: 1712654:A7C91_RS05185
uniprot id: A0A172WGV9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

1712654:A7C91 RS07875
gene id: 1712654:A7C91_RS07875
uniprot id: A0A172WI19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

1712654:A7C91 RS02360
gene id: 1712654:A7C91_RS02360
uniprot id: A0A172WFF3
names: Subcellular Location Annotation
messages: Membrane

1712654:A7C91 RS06445
gene id: 1712654:A7C91_RS06445
uniprot id: A0A172WHV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1712654:A7C91 RS03125
gene id: 1712654:A7C91_RS03125
uniprot id: A0A172WFS2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1712654:A7C91 RS00965
gene id: 1712654:A7C91_RS00965
uniprot id: A0A172WES4
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1712654:A7C91 RS02485
gene id: 1712654:A7C91_RS02485
uniprot id: A0A172WFH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S8 family.
messages: Monomer.
messages: Serine protease with a broad substrate specificity.