1654388:EL116 RS06140
gene id: 1654388:EL116_RS06140
uniprot id: A0A2K4ADS3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1654388:EL116 RS00680
gene id: 1654388:EL116_RS00680
uniprot id: A0A2K4ANA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS00305
gene id: 1654388:EL116_RS00305
uniprot id: A0A2K4AMV2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1654388:EL116 RS06135
gene id: 1654388:EL116_RS06135
uniprot id: A0A2K4AE38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1654388:EL116 RS01220
gene id: 1654388:EL116_RS01220
uniprot id: A0A2K4AIA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EssB family.
messages: Membrane

1654388:EL116 RS12235
gene id: 1654388:EL116_RS12235
uniprot id: A0A2K4AFT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1654388:EL116 RS11810
gene id: 1654388:EL116_RS11810
uniprot id: A0A2K4AG17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS07730
gene id: 1654388:EL116_RS07730
uniprot id: A0A2K4AG96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1654388:EL116 RS00650
gene id: 1654388:EL116_RS00650
uniprot id: A0A2K4AMD6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1654388:EL116 RS02765
gene id: 1654388:EL116_RS02765
uniprot id: A0A2K4AES2
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1654388:EL116 RS10785
gene id: 1654388:EL116_RS10785
uniprot id: A0A2K4AF27
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1654388:EL116 RS06210
gene id: 1654388:EL116_RS06210
uniprot id: A0A077UYF4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS07325
gene id: 1654388:EL116_RS07325
uniprot id: A0A2K4AIP8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1654388:EL116 RS06325
gene id: 1654388:EL116_RS06325
uniprot id: A0A2K4ADT9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1654388:EL116 RS04660
gene id: 1654388:EL116_RS04660
uniprot id: A0A077V0H5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Cell membrane
messages: May form a heterooligomeric complex that consists of seven subunits: mnhA1, mnhB1, mnhC1, mnhD1, mnhE1, mnhF1 and mnhG1.
messages: Membrane

1654388:EL116 RS13160
gene id: 1654388:EL116_RS13160
uniprot id: A0A2K4AHB2
names: Caution
names: Similarity
messages: Belongs to the TRAP family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS05980
gene id: 1654388:EL116_RS05980
uniprot id: A0A077V0M9
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS04640
gene id: 1654388:EL116_RS04640
uniprot id: A0A077W0R5
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

1654388:EL116 RS05110
gene id: 1654388:EL116_RS05110
uniprot id: A0A2K4AL14
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS01950
gene id: 1654388:EL116_RS01950
uniprot id: A0A2K4AIW2
names: Caution
names: Similarity
messages: Belongs to the staphylococcal tandem lipoprotein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS05565
gene id: 1654388:EL116_RS05565
uniprot id: A0A2K4AL70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IsdC family.
messages: cell wall

1654388:EL116 RS06185
gene id: 1654388:EL116_RS06185
uniprot id: A0A2K4ADX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1654388:EL116 RS06120
gene id: 1654388:EL116_RS06120
uniprot id: A0A077UVB6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1654388:EL116 RS02945
gene id: 1654388:EL116_RS02945
uniprot id: A0A2K4AED8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS07140
gene id: 1654388:EL116_RS07140
uniprot id: A0A2K4AHN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1654388:EL116 RS07855
gene id: 1654388:EL116_RS07855
uniprot id: A0A2K4AGE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1654388:EL116 RS13645
gene id: 1654388:EL116_RS13645
uniprot id: A0A2K4AP06
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS05130
gene id: 1654388:EL116_RS05130
uniprot id: A0A2K4AKX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1654388:EL116 RS01210
gene id: 1654388:EL116_RS01210
uniprot id: A0A2K4AJA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EssA family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS03815
gene id: 1654388:EL116_RS03815
uniprot id: A0A2K4AK06
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS06995
gene id: 1654388:EL116_RS06995
uniprot id: A0A2K4AI57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS03500
gene id: 1654388:EL116_RS03500
uniprot id: A0A2K4AJW2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer or homotrimer. Seems to be a monomer when not phosphorylated.
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1654388:EL116 RS05590
gene id: 1654388:EL116_RS05590
uniprot id: A0A2K4ALF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
messages: Belongs to the TRAP family.
messages: Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS10625
gene id: 1654388:EL116_RS10625
uniprot id: A0A2K4AEU6
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

1654388:EL116 RS04620
gene id: 1654388:EL116_RS04620
uniprot id: A0A2K4AKC4
names: Similarity
messages: Belongs to the peptidase M17 family.

1654388:EL116 RS09715
gene id: 1654388:EL116_RS09715
uniprot id: A0A2K4AJF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation using lipid-linked disaccharide-pentapeptide as the substrate.

1654388:EL116 RS07980
gene id: 1654388:EL116_RS07980
uniprot id: A0A2K4AGK1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1654388:EL116 RS07070
gene id: 1654388:EL116_RS07070
uniprot id: A0A077UZL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1654388:EL116 RS12175
gene id: 1654388:EL116_RS12175
uniprot id: A0A2K4AFP0
names: Caution
names: Similarity
messages: Belongs to the aerolysin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS04535
gene id: 1654388:EL116_RS04535
uniprot id: A0A2K4AM89
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1654388:EL116 RS02665
gene id: 1654388:EL116_RS02665
uniprot id: A0A2K4AFF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1654388:EL116 RS13285
gene id: 1654388:EL116_RS13285
uniprot id: A0A2K4AH97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carbamate kinase family.
messages: Cytoplasm

1654388:EL116 RS08550
gene id: 1654388:EL116_RS08550
uniprot id: A0A2K4AH44
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS10750
gene id: 1654388:EL116_RS10750
uniprot id: A0A2K4AF45
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1654388:EL116 RS00890
gene id: 1654388:EL116_RS00890
uniprot id: A0A2K4ANJ8
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS07530
gene id: 1654388:EL116_RS07530
uniprot id: A0A2K4AHS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS02565
gene id: 1654388:EL116_RS02565
uniprot id: A0A2K4AEL6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1654388:EL116 RS02265
gene id: 1654388:EL116_RS02265
uniprot id: A0A2K4AI16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1654388:EL116 RS11245
gene id: 1654388:EL116_RS11245
uniprot id: A0A077W1J5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1654388:EL116 RS11160
gene id: 1654388:EL116_RS11160
uniprot id: A0A077UKD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1654388:EL116 RS00005
gene id: 1654388:EL116_RS00005
uniprot id: A0A2K4AP17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1654388:EL116 RS05805
gene id: 1654388:EL116_RS05805
uniprot id: A0A2K4ADJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1654388:EL116 RS09285
gene id: 1654388:EL116_RS09285
uniprot id: A0A2K4AF87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the staphylococcal/streptococcal toxin family.
messages: Secreted

1654388:EL116 RS02135
gene id: 1654388:EL116_RS02135
uniprot id: A0A2K4AIY7
names: Similarity
messages: Belongs to the glutamate synthase family.

1654388:EL116 RS07000
gene id: 1654388:EL116_RS07000
uniprot id: A0A2K4AI24
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1654388:EL116 RS11715
gene id: 1654388:EL116_RS11715
uniprot id: A0A2K4AGD9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1654388:EL116 RS11735
gene id: 1654388:EL116_RS11735
uniprot id: A0A2K4AGS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1654388:EL116 RS00360
gene id: 1654388:EL116_RS00360
uniprot id: A0A2K4AMW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1654388:EL116 RS04495
gene id: 1654388:EL116_RS04495
uniprot id: A0A2K4AM58
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS02570
gene id: 1654388:EL116_RS02570
uniprot id: A0A2K4AEK3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1654388:EL116 RS09760
gene id: 1654388:EL116_RS09760
uniprot id: A0A2K4AJB3
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS05935
gene id: 1654388:EL116_RS05935
uniprot id: A0A2K4ADN4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1654388:EL116 RS12030
gene id: 1654388:EL116_RS12030
uniprot id: A0A2K4AG77
names: Cofactor
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Autophosphorylated.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1654388:EL116 RS02150
gene id: 1654388:EL116_RS02150
uniprot id: A0A2K4AJ96
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS11665
gene id: 1654388:EL116_RS11665
uniprot id: A0A2K4AG83
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS07435
gene id: 1654388:EL116_RS07435
uniprot id: A0A2K4AHP3
names: Similarity
messages: Belongs to the UPF0398 family.

1654388:EL116 RS08995
gene id: 1654388:EL116_RS08995
uniprot id: A0A2K4AG65
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS04605
gene id: 1654388:EL116_RS04605
uniprot id: A0A2K4ALC4
names: Similarity
messages: Belongs to the UPF0349 family.

1654388:EL116 RS08120
gene id: 1654388:EL116_RS08120
uniprot id: A0A077UHS1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1654388:EL116 RS08480
gene id: 1654388:EL116_RS08480
uniprot id: A0A2K4AGR3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS04825
gene id: 1654388:EL116_RS04825
uniprot id: A0A077VVY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS03870
gene id: 1654388:EL116_RS03870
uniprot id: A0A077UUA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1654388:EL116 RS05895
gene id: 1654388:EL116_RS05895
uniprot id: A0A2K4ADK5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1654388:EL116 RS10065
gene id: 1654388:EL116_RS10065
uniprot id: A0A2K4AJ55
names: Similarity
messages: Belongs to the aerolysin family.

1654388:EL116 RS10760
gene id: 1654388:EL116_RS10760
uniprot id: A0A2K4AEZ6
names: Function
names: Subunit
messages: Homodimer or homotrimer. Seems to be a monomer when not phosphorylated.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1654388:EL116 RS13055
gene id: 1654388:EL116_RS13055
uniprot id: A0A2K4AH96
names: Similarity
messages: Belongs to the fructosamine kinase family.

1654388:EL116 RS09820
gene id: 1654388:EL116_RS09820
uniprot id: A0A2K4AJD5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1654388:EL116 RS09105
gene id: 1654388:EL116_RS09105
uniprot id: A0A2K4AG48
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS11140
gene id: 1654388:EL116_RS11140
uniprot id: A0A2K4ALY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1654388:EL116 RS10255
gene id: 1654388:EL116_RS10255
uniprot id: A0A2K4AJ49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1654388:EL116 RS12230
gene id: 1654388:EL116_RS12230
uniprot id: A0A2K4AFL5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS00845
gene id: 1654388:EL116_RS00845
uniprot id: A0A2K4AMM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1654388:EL116 RS12920
gene id: 1654388:EL116_RS12920
uniprot id: A0A2K4AH50
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1654388:EL116 RS01955
gene id: 1654388:EL116_RS01955
uniprot id: A0A2K4AJ48
names: Similarity
messages: Belongs to the staphylococcal tandem lipoprotein family.

1654388:EL116 RS10220
gene id: 1654388:EL116_RS10220
uniprot id: A0A2K4AJE6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1654388:EL116 RS03485
gene id: 1654388:EL116_RS03485
uniprot id: A0A2K4AJT2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1654388:EL116 RS01365
gene id: 1654388:EL116_RS01365
uniprot id: A0A2K4AIM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. HrtB subfamily.
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

1654388:EL116 RS06280
gene id: 1654388:EL116_RS06280
uniprot id: A0A2K4AEM5
names: Similarity
messages: Belongs to the ribF family.

1654388:EL116 RS04945
gene id: 1654388:EL116_RS04945
uniprot id: A0A2K4AK79
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1654388:EL116 RS04415
gene id: 1654388:EL116_RS04415
uniprot id: A0A2K4AIA0
names: Similarity
messages: Belongs to the ArsC family.

1654388:EL116 RS00840
gene id: 1654388:EL116_RS00840
uniprot id: A0A2K4ANI8
names: Similarity
messages: Belongs to the staphylococcal tandem lipoprotein family.

1654388:EL116 RS08560
gene id: 1654388:EL116_RS08560
uniprot id: A0A2K4AGP7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1654388:EL116 RS09010
gene id: 1654388:EL116_RS09010
uniprot id: A0A2K4AFB5
names: Function
names: Similarity
messages: Belongs to the rot family.
messages: Global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence.

1654388:EL116 RS10965
gene id: 1654388:EL116_RS10965
uniprot id: A0A2K4AKL4
names: Cofactor
names: Subunit
messages: Binds 1 Mg(2+) ion per trimer.
messages: Homotrimer.

1654388:EL116 RS06935
gene id: 1654388:EL116_RS06935
uniprot id: A0A2K4AHX4
names: Similarity
names: Subunit
messages: Belongs to the SMC family. SbcC subfamily.
messages: Heterodimer of SbcC and SbcD.

1654388:EL116 RS08915
gene id: 1654388:EL116_RS08915
uniprot id: A0A2K4AFB7
names: Similarity
messages: Belongs to the UPF0354 family.

1654388:EL116 RS11020
gene id: 1654388:EL116_RS11020
uniprot id: A0A3S4NET6
names: Similarity
messages: Belongs to the peptidase S1B family.

1654388:EL116 RS02045
gene id: 1654388:EL116_RS02045
uniprot id: A0A2K4AJ78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

1654388:EL116 RS03130
gene id: 1654388:EL116_RS03130
uniprot id: A0A2K4AEA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS03175
gene id: 1654388:EL116_RS03175
uniprot id: A0A2K4AE95
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1654388:EL116 RS07870
gene id: 1654388:EL116_RS07870
uniprot id: A0A2K4AGT4
names: Function
names: Similarity
messages: Belongs to the asp23 family.
messages: May play a key role in alkaline pH tolerance.

1654388:EL116 RS00450
gene id: 1654388:EL116_RS00450
uniprot id: A0A2K4AEX3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1654388:EL116 RS02695
gene id: 1654388:EL116_RS02695
uniprot id: A0A2K4AEN4
names: Similarity
messages: Belongs to the ribulokinase family.

1654388:EL116 RS03655
gene id: 1654388:EL116_RS03655
uniprot id: A0A2K4AJZ4
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1654388:EL116 RS12900
gene id: 1654388:EL116_RS12900
uniprot id: A0A2K4ALU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1654388:EL116 RS10295
gene id: 1654388:EL116_RS10295
uniprot id: A0A2K4AEN1
names: Caution
names: Function
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS09655
gene id: 1654388:EL116_RS09655
uniprot id: A0A2K4AJG8
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Homodimer; disulfide-linked, upon oxidation. 5 homodimers assemble to form a ring-like decamer.

1654388:EL116 RS08325
gene id: 1654388:EL116_RS08325
uniprot id: A0A2K4AGM9
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1654388:EL116 RS11210
gene id: 1654388:EL116_RS11210
uniprot id: A0A2K4ALX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1654388:EL116 RS09895
gene id: 1654388:EL116_RS09895
uniprot id: A0A2K4AJL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homodimer and homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1654388:EL116 RS03145
gene id: 1654388:EL116_RS03145
uniprot id: A0A2K4AEF2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1654388:EL116 RS08420
gene id: 1654388:EL116_RS08420
uniprot id: A0A2K4AGL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1654388:EL116 RS04965
gene id: 1654388:EL116_RS04965
uniprot id: A0A077V0L7
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

1654388:EL116 RS11010
gene id: 1654388:EL116_RS11010
uniprot id: A0A2K4AJI9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS10590
gene id: 1654388:EL116_RS10590
uniprot id: A0A2K4AEW1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1654388:EL116 RS00740
gene id: 1654388:EL116_RS00740
uniprot id: A0A2K4AMJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

1654388:EL116 RS11720
gene id: 1654388:EL116_RS11720
uniprot id: A0A2K4AG73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fosfomycin resistance protein family. FosB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.

1654388:EL116 RS13190
gene id: 1654388:EL116_RS13190
uniprot id: A0A2K4AH89
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS02910
gene id: 1654388:EL116_RS02910
uniprot id: A0A2K4AEJ1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1654388:EL116 RS00420
gene id: 1654388:EL116_RS00420
uniprot id: A0A2K4AN22
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS04880
gene id: 1654388:EL116_RS04880
uniprot id: A0A2K4AK76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

1654388:EL116 RS08150
gene id: 1654388:EL116_RS08150
uniprot id: A0A2K4AGG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1654388:EL116 RS06230
gene id: 1654388:EL116_RS06230
uniprot id: A0A2K4ADR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1654388:EL116 RS04850
gene id: 1654388:EL116_RS04850
uniprot id: A0A2K4AKH1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS06975
gene id: 1654388:EL116_RS06975
uniprot id: A0A2K4AHR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1654388:EL116 RS03035
gene id: 1654388:EL116_RS03035
uniprot id: A0A2K4AEC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1654388:EL116 RS03505
gene id: 1654388:EL116_RS03505
uniprot id: A0A2K4AJT6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1654388:EL116 RS10390
gene id: 1654388:EL116_RS10390
uniprot id: A0A2K4AF52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

1654388:EL116 RS13810
gene id: 1654388:EL116_RS13810
uniprot id: A0A2K4ANI4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS06085
gene id: 1654388:EL116_RS06085
uniprot id: A0A2K4AE29
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1654388:EL116 RS08500
gene id: 1654388:EL116_RS08500
uniprot id: A0A448CX17
names: Similarity
messages: Belongs to the UPF0758 family.

1654388:EL116 RS05990
gene id: 1654388:EL116_RS05990
uniprot id: A0A2K4ADM6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1654388:EL116 RS12105
gene id: 1654388:EL116_RS12105
uniprot id: A0A2K4AFN5
names: Similarity
messages: Belongs to the YoeB family.

1654388:EL116 RS11385
gene id: 1654388:EL116_RS11385
uniprot id: A0A2K4ALU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1654388:EL116 RS07165
gene id: 1654388:EL116_RS07165
uniprot id: A0A2K4AHN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homodimer.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1654388:EL116 RS05370
gene id: 1654388:EL116_RS05370
uniprot id: A0A2K4AL56
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1654388:EL116 RS10525
gene id: 1654388:EL116_RS10525
uniprot id: A0A077UX57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1654388:EL116 RS07700
gene id: 1654388:EL116_RS07700
uniprot id: A0A2K4AGB2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

1654388:EL116 RS06835
gene id: 1654388:EL116_RS06835
uniprot id: A0A2K4AHW8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1654388:EL116 RS08965
gene id: 1654388:EL116_RS08965
uniprot id: A0A2K4AFA9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1654388:EL116 RS05835
gene id: 1654388:EL116_RS05835
uniprot id: A0A2K4ADJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

1654388:EL116 RS05435
gene id: 1654388:EL116_RS05435
uniprot id: A0A2K4AL41
names: Similarity
messages: Belongs to the UPF0637 family.

1654388:EL116 RS03510
gene id: 1654388:EL116_RS03510
uniprot id: A0A2K4AJV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1654388:EL116 RS08545
gene id: 1654388:EL116_RS08545
uniprot id: A0A2K4AH04
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1654388:EL116 RS13635
gene id: 1654388:EL116_RS13635
uniprot id: A0A2K4ANX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. HrtB subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

1654388:EL116 RS00730
gene id: 1654388:EL116_RS00730
uniprot id: A0A2K4AML9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1654388:EL116 RS02075
gene id: 1654388:EL116_RS02075
uniprot id: A0A2K4AJZ0
names: Subunit
messages: Homodimer.

1654388:EL116 RS01545
gene id: 1654388:EL116_RS01545
uniprot id: A0A2K4AJQ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1654388:EL116 RS13680
gene id: 1654388:EL116_RS13680
uniprot id: A0A2K4AP00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS11175
gene id: 1654388:EL116_RS11175
uniprot id: W8TUD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1654388:EL116 RS07270
gene id: 1654388:EL116_RS07270
uniprot id: A0A2K4AHL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1654388:EL116 RS10550
gene id: 1654388:EL116_RS10550
uniprot id: A0A2K4AF80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS09185
gene id: 1654388:EL116_RS09185
uniprot id: A0A2K4AF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the staphylococcal/streptococcal toxin family.
messages: Secreted

1654388:EL116 RS08640
gene id: 1654388:EL116_RS08640
uniprot id: A0A2K4AHR0
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

1654388:EL116 RS01140
gene id: 1654388:EL116_RS01140
uniprot id: A0A2K4AIM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1654388:EL116 RS05115
gene id: 1654388:EL116_RS05115
uniprot id: A0A2K4ALW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1654388:EL116 RS09740
gene id: 1654388:EL116_RS09740
uniprot id: A0A2K4AJE5
names: Similarity
messages: Belongs to the peptidase M29 family.

1654388:EL116 RS00075
gene id: 1654388:EL116_RS00075
uniprot id: A0A2K4AP13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1654388:EL116 RS13500
gene id: 1654388:EL116_RS13500
uniprot id: A0A2K4ANU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1654388:EL116 RS04905
gene id: 1654388:EL116_RS04905
uniprot id: A0A2K4AKE8
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1654388:EL116 RS08515
gene id: 1654388:EL116_RS08515
uniprot id: A0A2K4AGP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1654388:EL116 RS12140
gene id: 1654388:EL116_RS12140
uniprot id: A0A2K4AFZ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS10680
gene id: 1654388:EL116_RS10680
uniprot id: A0A2K4AEZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1654388:EL116 RS06405
gene id: 1654388:EL116_RS06405
uniprot id: A0A2K4AE88
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1654388:EL116 RS10195
gene id: 1654388:EL116_RS10195
uniprot id: A0A2K4AJ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1654388:EL116 RS00945
gene id: 1654388:EL116_RS00945
uniprot id: A0A2K4AJX7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1654388:EL116 RS07170
gene id: 1654388:EL116_RS07170
uniprot id: A0A2K4AIS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1654388:EL116 RS07345
gene id: 1654388:EL116_RS07345
uniprot id: A0A2K4AHJ1
names: Similarity
messages: Belongs to the UPF0403 family.

1654388:EL116 RS05320
gene id: 1654388:EL116_RS05320
uniprot id: A0A077UTV3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1654388:EL116 RS08130
gene id: 1654388:EL116_RS08130
uniprot id: A0A2K4AGK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1654388:EL116 RS04560
gene id: 1654388:EL116_RS04560
uniprot id: A0A2K4AM78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
messages: Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS08770
gene id: 1654388:EL116_RS08770
uniprot id: A0A2K4AH41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1654388:EL116 RS09155
gene id: 1654388:EL116_RS09155
uniprot id: A0A2K4AFB3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

1654388:EL116 RS13690
gene id: 1654388:EL116_RS13690
uniprot id: W8TQ59
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1654388:EL116 RS05985
gene id: 1654388:EL116_RS05985
uniprot id: A0A2K4ADP5
names: Caution
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1654388:EL116 RS03000
gene id: 1654388:EL116_RS03000
uniprot id: A0A2K4AEE1
names: Similarity
names: Subunit
messages: Belongs to the azoreductase type 2 family.
messages: Homotetramer.

1654388:EL116 RS05850
gene id: 1654388:EL116_RS05850
uniprot id: A0A077UYN0
names: Function
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.
messages: Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine. Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate. Also has adenosine deaminase activity.

1654388:EL116 RS00515
gene id: 1654388:EL116_RS00515
uniprot id: A0A2K4ALM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS11705
gene id: 1654388:EL116_RS11705
uniprot id: A0A2K4AFW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1654388:EL116 RS02315
gene id: 1654388:EL116_RS02315
uniprot id: A0A2K4AI41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1654388:EL116 RS01865
gene id: 1654388:EL116_RS01865
uniprot id: A0A2K4AIR5
names: Similarity
messages: Belongs to the staphylococcal/streptococcal toxin family.

1654388:EL116 RS03315
gene id: 1654388:EL116_RS03315
uniprot id: A0A2K4AKG8
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS08880
gene id: 1654388:EL116_RS08880
uniprot id: A0A2K4AFN2
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1654388:EL116 RS03735
gene id: 1654388:EL116_RS03735
uniprot id: A0A2K4AJX4
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS00440
gene id: 1654388:EL116_RS00440
uniprot id: A0A2K4AEV8
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.

1654388:EL116 RS11285
gene id: 1654388:EL116_RS11285
uniprot id: W8U3W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1654388:EL116 RS11505
gene id: 1654388:EL116_RS11505
uniprot id: A0A2K4ALW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1654388:EL116 RS11235
gene id: 1654388:EL116_RS11235
uniprot id: A0A077UUA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1654388:EL116 RS05250
gene id: 1654388:EL116_RS05250
uniprot id: A0A2K4AL27
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1654388:EL116 RS10095
gene id: 1654388:EL116_RS10095
uniprot id: A0A2K4AJ80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1654388:EL116 RS03825
gene id: 1654388:EL116_RS03825
uniprot id: A0A2K4AK37
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1654388:EL116 RS02640
gene id: 1654388:EL116_RS02640
uniprot id: A0A2K4AEZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1654388:EL116 RS13580
gene id: 1654388:EL116_RS13580
uniprot id: A0A2K4ANW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1654388:EL116 RS06035
gene id: 1654388:EL116_RS06035
uniprot id: A0A2K4ADQ2
names: Function
names: Similarity
messages: Belongs to the asp23 family.
messages: May play a key role in alkaline pH tolerance.

1654388:EL116 RS00145
gene id: 1654388:EL116_RS00145
uniprot id: A0A2K4AMW9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1654388:EL116 RS02605
gene id: 1654388:EL116_RS02605
uniprot id: A0A2K4AFG0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1654388:EL116 RS00785
gene id: 1654388:EL116_RS00785
uniprot id: A0A2K4AMN0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS05785
gene id: 1654388:EL116_RS05785
uniprot id: A0A2K4ADI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the staphylococcal hemolytic protein family.
messages: Secreted

1654388:EL116 RS02515
gene id: 1654388:EL116_RS02515
uniprot id: A0A2K4AF13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1654388:EL116 RS01060
gene id: 1654388:EL116_RS01060
uniprot id: A0A2K4AHA0
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1654388:EL116 RS11165
gene id: 1654388:EL116_RS11165
uniprot id: A0A2K4ALX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1654388:EL116 RS02785
gene id: 1654388:EL116_RS02785
uniprot id: A0A2K4AEG9
names: Function
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.
messages: Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate.

1654388:EL116 RS13505
gene id: 1654388:EL116_RS13505
uniprot id: A0A2K4ANX6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1654388:EL116 RS08575
gene id: 1654388:EL116_RS08575
uniprot id: A0A2K4AGU9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS09450
gene id: 1654388:EL116_RS09450
uniprot id: A0A077VK48
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1654388:EL116 RS01085
gene id: 1654388:EL116_RS01085
uniprot id: A0A2K4AIJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RIC family. ScdA subfamily.
messages: Cytoplasm
messages: Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
messages: Homodimer.

1654388:EL116 RS07535
gene id: 1654388:EL116_RS07535
uniprot id: A0A2K4AHJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1654388:EL116 RS10340
gene id: 1654388:EL116_RS10340
uniprot id: A0A2K4AF43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1654388:EL116 RS12805
gene id: 1654388:EL116_RS12805
uniprot id: A0A2K4ALL8
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS06115
gene id: 1654388:EL116_RS06115
uniprot id: A0A2K4ADP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1654388:EL116 RS00535
gene id: 1654388:EL116_RS00535
uniprot id: A0A2K4ALH1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1654388:EL116 RS07025
gene id: 1654388:EL116_RS07025
uniprot id: A0A2K4AHQ4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1654388:EL116 RS05970
gene id: 1654388:EL116_RS05970
uniprot id: A0A2K4ADR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1654388:EL116 RS05405
gene id: 1654388:EL116_RS05405
uniprot id: A0A2K4AL28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS12405
gene id: 1654388:EL116_RS12405
uniprot id: A0A2K4AFK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS12935
gene id: 1654388:EL116_RS12935
uniprot id: A0A2K4AH78
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1654388:EL116 RS04570
gene id: 1654388:EL116_RS04570
uniprot id: W8U0E0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

1654388:EL116 RS01890
gene id: 1654388:EL116_RS01890
uniprot id: A0A2K4AIS9
names: Similarity
messages: Belongs to the staphylococcal/streptococcal toxin family.

1654388:EL116 RS12950
gene id: 1654388:EL116_RS12950
uniprot id: A0A2K4AHH3
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1654388:EL116 RS01405
gene id: 1654388:EL116_RS01405
uniprot id: A0A2K4AIU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family. NanA subfamily.
messages: Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
messages: Cytoplasm
messages: Homotetramer.

1654388:EL116 RS04575
gene id: 1654388:EL116_RS04575
uniprot id: A0A2K4AM75
names: Similarity
messages: Belongs to the DltD family.

1654388:EL116 RS12320
gene id: 1654388:EL116_RS12320
uniprot id: A0A2K4AFK1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1654388:EL116 RS02550
gene id: 1654388:EL116_RS02550
uniprot id: A0A3S4N5Y8
names: Similarity
messages: Belongs to the ycf81 family.

1654388:EL116 RS06870
gene id: 1654388:EL116_RS06870
uniprot id: A0A2K4AHT7
names: Similarity
names: Subunit
messages: Belongs to the catalase family.
messages: Homodimer.

1654388:EL116 RS05890
gene id: 1654388:EL116_RS05890
uniprot id: A0A2K4ADK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1654388:EL116 RS13390
gene id: 1654388:EL116_RS13390
uniprot id: A0A2K4ALE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.
messages: Cell membrane
messages: Component of the accessory SecA2/SecY2 protein translocase complex required to export cell wall proteins. May form heterotrimers with SecE and SecG subunits.
messages: Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins. The central subunit of a protein translocation channel.

1654388:EL116 RS04980
gene id: 1654388:EL116_RS04980
uniprot id: A0A2K4AKU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. UgtP subfamily.
messages: Cell membrane
messages: Membrane
messages: Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer two glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).

1654388:EL116 RS03410
gene id: 1654388:EL116_RS03410
uniprot id: A0A2K4AKM2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS11420
gene id: 1654388:EL116_RS11420
uniprot id: A0A2K4ALS0
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1654388:EL116 RS06190
gene id: 1654388:EL116_RS06190
uniprot id: A0A2K4AE46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

1654388:EL116 RS07620
gene id: 1654388:EL116_RS07620
uniprot id: W8U5S9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1654388:EL116 RS02790
gene id: 1654388:EL116_RS02790
uniprot id: A0A2K4AEH0
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1654388:EL116 RS07830
gene id: 1654388:EL116_RS07830
uniprot id: A0A2K4AGA5
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1654388:EL116 RS12300
gene id: 1654388:EL116_RS12300
uniprot id: A0A2K4AFN7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS05845
gene id: 1654388:EL116_RS05845
uniprot id: A0A2K4ADJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1654388:EL116 RS07475
gene id: 1654388:EL116_RS07475
uniprot id: A0A2K4AHK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS01420
gene id: 1654388:EL116_RS01420
uniprot id: A0A2K4AIJ3
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1654388:EL116 RS07985
gene id: 1654388:EL116_RS07985
uniprot id: A0A2K4AGD5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS10775
gene id: 1654388:EL116_RS10775
uniprot id: A0A2K4AFU6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1654388:EL116 RS04235
gene id: 1654388:EL116_RS04235
uniprot id: A0A2K4ANM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Belongs to the transglycosylase family. IsaA subfamily.
messages: Is able to cleave peptidoglycan.
messages: Secreted

1654388:EL116 RS09875
gene id: 1654388:EL116_RS09875
uniprot id: A0A2K4AJC2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1654388:EL116 RS12465
gene id: 1654388:EL116_RS12465
uniprot id: A0A2K4AFK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1654388:EL116 RS02015
gene id: 1654388:EL116_RS02015
uniprot id: A0A2K4AIX0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1654388:EL116 RS10640
gene id: 1654388:EL116_RS10640
uniprot id: A0A2K4AEX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS09485
gene id: 1654388:EL116_RS09485
uniprot id: A0A2K4AFY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS01215
gene id: 1654388:EL116_RS01215
uniprot id: A0A077VQA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EsaB family.
messages: Cytoplasm

1654388:EL116 RS10670
gene id: 1654388:EL116_RS10670
uniprot id: A0A2K4AEW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1654388:EL116 RS01390
gene id: 1654388:EL116_RS01390
uniprot id: A0A2K4AJM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1654388:EL116 RS07390
gene id: 1654388:EL116_RS07390
uniprot id: A0A2K4AHH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

1654388:EL116 RS08115
gene id: 1654388:EL116_RS08115
uniprot id: A0A2K4AGU0
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS10885
gene id: 1654388:EL116_RS10885
uniprot id: A0A2K4AJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1654388:EL116 RS05530
gene id: 1654388:EL116_RS05530
uniprot id: A0A077UM22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1654388:EL116 RS07295
gene id: 1654388:EL116_RS07295
uniprot id: A0A2K4AHK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS08690
gene id: 1654388:EL116_RS08690
uniprot id: A0A2K4AGR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1654388:EL116 RS10555
gene id: 1654388:EL116_RS10555
uniprot id: A0A2K4AEZ7
names: Caution
names: Similarity
messages: Belongs to the UPF0340 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS02865
gene id: 1654388:EL116_RS02865
uniprot id: A0A2K4AEN9
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1654388:EL116 RS10400
gene id: 1654388:EL116_RS10400
uniprot id: A0A2K4AEW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1654388:EL116 RS05830
gene id: 1654388:EL116_RS05830
uniprot id: A0A2K4ADJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1654388:EL116 RS02040
gene id: 1654388:EL116_RS02040
uniprot id: A0A2K4AJ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

1654388:EL116 RS03105
gene id: 1654388:EL116_RS03105
uniprot id: A0A2K4AEJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS04045
gene id: 1654388:EL116_RS04045
uniprot id: A0A2K4ANQ8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1654388:EL116 RS03800
gene id: 1654388:EL116_RS03800
uniprot id: A0A2K4AK88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1654388:EL116 RS13470
gene id: 1654388:EL116_RS13470
uniprot id: A0A2K4ALJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IcaD family.
messages: Cell membrane
messages: Necessary for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Is required for full IcaA N-acetylglucosaminyltransferase activity.

1654388:EL116 RS00710
gene id: 1654388:EL116_RS00710
uniprot id: A0A2K4AMJ7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1654388:EL116 RS03115
gene id: 1654388:EL116_RS03115
uniprot id: A0A2K4AEC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1654388:EL116 RS12250
gene id: 1654388:EL116_RS12250
uniprot id: A0A2K4AFP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS07060
gene id: 1654388:EL116_RS07060
uniprot id: A0A2K4AHQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1654388:EL116 RS05335
gene id: 1654388:EL116_RS05335
uniprot id: A0A2K4AL20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS07310
gene id: 1654388:EL116_RS07310
uniprot id: A0A2K4AHV8
names: Similarity
messages: Belongs to the UPF0346 family.

1654388:EL116 RS01395
gene id: 1654388:EL116_RS01395
uniprot id: A0A2K4AII4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1654388:EL116 RS04885
gene id: 1654388:EL116_RS04885
uniprot id: A0A2K4AK75
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1654388:EL116 RS13090
gene id: 1654388:EL116_RS13090
uniprot id: W8U7T6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1654388:EL116 RS06875
gene id: 1654388:EL116_RS06875
uniprot id: A0A077V2P0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1654388:EL116 RS09280
gene id: 1654388:EL116_RS09280
uniprot id: A0A2K4AF99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the staphylococcal/streptococcal toxin family.
messages: Secreted

1654388:EL116 RS08060
gene id: 1654388:EL116_RS08060
uniprot id: A0A2K4AHE8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1654388:EL116 RS11570
gene id: 1654388:EL116_RS11570
uniprot id: A0A2K4AGV3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1654388:EL116 RS11065
gene id: 1654388:EL116_RS11065
uniprot id: A0A2K4AJV1
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1654388:EL116 RS06245
gene id: 1654388:EL116_RS06245
uniprot id: A0A2K4ADY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1654388:EL116 RS00115
gene id: 1654388:EL116_RS00115
uniprot id: A0A2K4AMS4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS04760
gene id: 1654388:EL116_RS04760
uniprot id: A0A2K4AK94
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide.
messages: Contains 2 FAD binding domains and a single NADPH binding domain.
messages: Homodimer.
messages: Reduction of disulfides occurs by a thiol-disulfide exchange reaction, but involves only a single catalytic cysteine residue that forms a stable mixed disulfide with CoA during catalysis.

1654388:EL116 RS01520
gene id: 1654388:EL116_RS01520
uniprot id: A0A2K4AIK6
names: Similarity
names: Subunit
messages: Belongs to the azoreductase type 2 family.
messages: Homotetramer.

1654388:EL116 RS08855
gene id: 1654388:EL116_RS08855
uniprot id: A0A2K4AFD0
names: Subcellular Location Annotation
messages: cell wall

1654388:EL116 RS11410
gene id: 1654388:EL116_RS11410
uniprot id: A0A2K4AM24
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1654388:EL116 RS03420
gene id: 1654388:EL116_RS03420
uniprot id: A0A2K4AKI9
names: Function
names: Subcellular Location Annotation
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.
messages: Membrane

1654388:EL116 RS04860
gene id: 1654388:EL116_RS04860
uniprot id: A0A2K4AK82
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1654388:EL116 RS12205
gene id: 1654388:EL116_RS12205
uniprot id: A0A2K4AFP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1654388:EL116 RS06150
gene id: 1654388:EL116_RS06150
uniprot id: A0A2K4ADQ5
names: Function
names: Subcellular Location Annotation
messages: Probably involved in peptidoglycan hydrolysis.
messages: Secreted

1654388:EL116 RS06180
gene id: 1654388:EL116_RS06180
uniprot id: A0A2K4ADU1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1654388:EL116 RS10545
gene id: 1654388:EL116_RS10545
uniprot id: A0A2K4AF25
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1654388:EL116 RS09815
gene id: 1654388:EL116_RS09815
uniprot id: A0A2K4AKC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1654388:EL116 RS06060
gene id: 1654388:EL116_RS06060
uniprot id: A0A2K4AEI5
names: Similarity
messages: Belongs to the fabD family.

1654388:EL116 RS10470
gene id: 1654388:EL116_RS10470
uniprot id: A0A2K4AER4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS11695
gene id: 1654388:EL116_RS11695
uniprot id: A0A2K4AGW3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS00035
gene id: 1654388:EL116_RS00035
uniprot id: A0A2K4APV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1654388:EL116 RS13335
gene id: 1654388:EL116_RS13335
uniprot id: A0A2K4AHA6
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1654388:EL116 RS02680
gene id: 1654388:EL116_RS02680
uniprot id: A0A2K4AEJ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS01635
gene id: 1654388:EL116_RS01635
uniprot id: A0A2K4AIS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1654388:EL116 RS12040
gene id: 1654388:EL116_RS12040
uniprot id: A0A2K4AFT6
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS04565
gene id: 1654388:EL116_RS04565
uniprot id: A0A2K4AMA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

1654388:EL116 RS04625
gene id: 1654388:EL116_RS04625
uniprot id: A0A2K4AKC2
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS09275
gene id: 1654388:EL116_RS09275
uniprot id: A0A2K4AFF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the staphylococcal/streptococcal toxin family.
messages: Secreted

1654388:EL116 RS04515
gene id: 1654388:EL116_RS04515
uniprot id: A0A2K4AM65
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1654388:EL116 RS06845
gene id: 1654388:EL116_RS06845
uniprot id: A0A2K4AIX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1654388:EL116 RS02590
gene id: 1654388:EL116_RS02590
uniprot id: A0A2K4AEU8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

1654388:EL116 RS01195
gene id: 1654388:EL116_RS01195
uniprot id: A0A2K4AIH6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS02875
gene id: 1654388:EL116_RS02875
uniprot id: A0A2K4AEI3
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

1654388:EL116 RS01180
gene id: 1654388:EL116_RS01180
uniprot id: A0A2K4AI70
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS08895
gene id: 1654388:EL116_RS08895
uniprot id: A0A2K4AG84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0478 family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS12150
gene id: 1654388:EL116_RS12150
uniprot id: A0A448CYU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS02495
gene id: 1654388:EL116_RS02495
uniprot id: A0A448CTM4
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

1654388:EL116 RS08085
gene id: 1654388:EL116_RS08085
uniprot id: A0A2K4AGX2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1654388:EL116 RS05635
gene id: 1654388:EL116_RS05635
uniprot id: A0A2K4ADK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1654388:EL116 RS04540
gene id: 1654388:EL116_RS04540
uniprot id: A0A2K4AM74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

1654388:EL116 RS06450
gene id: 1654388:EL116_RS06450
uniprot id: A0A2K4ADZ8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1654388:EL116 RS10175
gene id: 1654388:EL116_RS10175
uniprot id: A0A2K4AJ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1654388:EL116 RS08285
gene id: 1654388:EL116_RS08285
uniprot id: A0A2K4AGV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1654388:EL116 RS08160
gene id: 1654388:EL116_RS08160
uniprot id: A0A2K4AGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1654388:EL116 RS00545
gene id: 1654388:EL116_RS00545
uniprot id: A0A2K4AME9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1654388:EL116 RS11830
gene id: 1654388:EL116_RS11830
uniprot id: A0A2K4AFW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tcaA family.
messages: Cell membrane

1654388:EL116 RS13215
gene id: 1654388:EL116_RS13215
uniprot id: A0A2K4AHI3
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

1654388:EL116 RS05485
gene id: 1654388:EL116_RS05485
uniprot id: A0A2K4AL49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 1 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS06410
gene id: 1654388:EL116_RS06410
uniprot id: A0A2K4ADX8
names: Caution
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS03555
gene id: 1654388:EL116_RS03555
uniprot id: A0A2K4AJU8
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1654388:EL116 RS09970
gene id: 1654388:EL116_RS09970
uniprot id: A0A2K4AK96
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1654388:EL116 RS06400
gene id: 1654388:EL116_RS06400
uniprot id: A0A2K4AE19
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1654388:EL116 RS04505
gene id: 1654388:EL116_RS04505
uniprot id: A0A2K4AM94
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS11190
gene id: 1654388:EL116_RS11190
uniprot id: A0A077UGA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1654388:EL116 RS12305
gene id: 1654388:EL116_RS12305
uniprot id: A0A2K4AFM9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS02375
gene id: 1654388:EL116_RS02375
uniprot id: A0A2K4AHZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1654388:EL116 RS06220
gene id: 1654388:EL116_RS06220
uniprot id: A0A2K4ADR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1654388:EL116 RS08435
gene id: 1654388:EL116_RS08435
uniprot id: A0A2K4AGR2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1654388:EL116 RS05265
gene id: 1654388:EL116_RS05265
uniprot id: A0A2K4AL11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1654388:EL116 RS12165
gene id: 1654388:EL116_RS12165
uniprot id: A0A2K4AFM5
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS01595
gene id: 1654388:EL116_RS01595
uniprot id: A0A3S4S3P8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1654388:EL116 RS03660
gene id: 1654388:EL116_RS03660
uniprot id: A0A2K4AJW9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1654388:EL116 RS00085
gene id: 1654388:EL116_RS00085
uniprot id: A0A2K4AP26
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1654388:EL116 RS05385
gene id: 1654388:EL116_RS05385
uniprot id: A0A2K4AL34
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.
messages: Membrane
messages: The active site is a redox-active disulfide bond.

1654388:EL116 RS10845
gene id: 1654388:EL116_RS10845
uniprot id: A0A2K4AJW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS02625
gene id: 1654388:EL116_RS02625
uniprot id: A0A2K4AEK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1654388:EL116 RS03620
gene id: 1654388:EL116_RS03620
uniprot id: A0A2K4AJX6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1654388:EL116 RS03180
gene id: 1654388:EL116_RS03180
uniprot id: A0A2K4AEA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS12585
gene id: 1654388:EL116_RS12585
uniprot id: A0A2K4AG60
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS03895
gene id: 1654388:EL116_RS03895
uniprot id: A0A2K4AL22
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

1654388:EL116 RS13300
gene id: 1654388:EL116_RS13300
uniprot id: A0A2K4AIC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1654388:EL116 RS12860
gene id: 1654388:EL116_RS12860
uniprot id: A0A2K4ALM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1654388:EL116 RS03805
gene id: 1654388:EL116_RS03805
uniprot id: A0A2K4AK28
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1654388:EL116 RS09685
gene id: 1654388:EL116_RS09685
uniprot id: A0A2K4AJF6
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1654388:EL116 RS08220
gene id: 1654388:EL116_RS08220
uniprot id: A0A2K4AHH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1654388:EL116 RS13105
gene id: 1654388:EL116_RS13105
uniprot id: A0A2K4AH83
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1654388:EL116 RS05215
gene id: 1654388:EL116_RS05215
uniprot id: A0A2K4AL02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS10595
gene id: 1654388:EL116_RS10595
uniprot id: A0A2K4AEY3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS04985
gene id: 1654388:EL116_RS04985
uniprot id: A0A2K4AKU3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS00095
gene id: 1654388:EL116_RS00095
uniprot id: A0A2K4AP22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1654388:EL116 RS07145
gene id: 1654388:EL116_RS07145
uniprot id: A0A2K4AHT8
names: Similarity
messages: Belongs to the CvfB family.

1654388:EL116 RS08170
gene id: 1654388:EL116_RS08170
uniprot id: A0A2K4AHG7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1654388:EL116 RS01480
gene id: 1654388:EL116_RS01480
uniprot id: A0A2K4AIN4
names: Function
names: Subunit
messages: Homodimer or homotrimer. Seems to be a monomer when not phosphorylated.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1654388:EL116 RS09720
gene id: 1654388:EL116_RS09720
uniprot id: A0A2K4AJE8
names: Caution
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS02630
gene id: 1654388:EL116_RS02630
uniprot id: A0A077W1M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1654388:EL116 RS12830
gene id: 1654388:EL116_RS12830
uniprot id: A0A2K4ALL1
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1654388:EL116 RS02950
gene id: 1654388:EL116_RS02950
uniprot id: A0A2K4AFI0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS11090
gene id: 1654388:EL116_RS11090
uniprot id: A0A2K4AM46
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS06385
gene id: 1654388:EL116_RS06385
uniprot id: A0A2K4AEP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1654388:EL116 RS03665
gene id: 1654388:EL116_RS03665
uniprot id: A0A2K4AJY0
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

1654388:EL116 RS13235
gene id: 1654388:EL116_RS13235
uniprot id: A0A2K4AH86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. HrtA family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

1654388:EL116 RS13275
gene id: 1654388:EL116_RS13275
uniprot id: A0A3S4N9A8
names: Subcellular Location Annotation
messages: cell wall

1654388:EL116 RS07860
gene id: 1654388:EL116_RS07860
uniprot id: A0A2K4AGF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1654388:EL116 RS07735
gene id: 1654388:EL116_RS07735
uniprot id: A0A2K4AG97
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS09345
gene id: 1654388:EL116_RS09345
uniprot id: A0A2K4AF59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1654388:EL116 RS06665
gene id: 1654388:EL116_RS06665
uniprot id: A0A2K4AE56
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS07575
gene id: 1654388:EL116_RS07575
uniprot id: A0A2K4AHL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1654388:EL116 RS11770
gene id: 1654388:EL116_RS11770
uniprot id: A0A2K4AG62
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1654388:EL116 RS06430
gene id: 1654388:EL116_RS06430
uniprot id: A0A2K4ADV7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1654388:EL116 RS01205
gene id: 1654388:EL116_RS01205
uniprot id: A0A2K4AI69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EsaA family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS00470
gene id: 1654388:EL116_RS00470
uniprot id: A0A2K4AF54
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1654388:EL116 RS05010
gene id: 1654388:EL116_RS05010
uniprot id: A0A2K4AKW8
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS12360
gene id: 1654388:EL116_RS12360
uniprot id: A0A2K4AGF2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1654388:EL116 RS09250
gene id: 1654388:EL116_RS09250
uniprot id: A0A2K4AF53
names: Function
names: PTM
names: Similarity
messages: Belongs to the type A lantibiotic family.
messages: Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.
messages: Maturation of lantibiotics involves the enzymatic conversion of Thr, and Ser into dehydrated AA and the formation of thioether bonds with cysteine. This is followed by membrane translocation and cleavage of the modified precursor.

1654388:EL116 RS07905
gene id: 1654388:EL116_RS07905
uniprot id: A0A2K4AGF0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the octanoyltransferase LipM family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. The reaction proceeds via an octanoyl-thioester enzyme intermediate.
messages: Monomer.

1654388:EL116 RS12160
gene id: 1654388:EL116_RS12160
uniprot id: A0A2K4AGJ3
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1654388:EL116 RS07525
gene id: 1654388:EL116_RS07525
uniprot id: A0A2K4AHV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1654388:EL116 RS03020
gene id: 1654388:EL116_RS03020
uniprot id: A0A2K4AEC7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1654388:EL116 RS00025
gene id: 1654388:EL116_RS00025
uniprot id: A0A2K4AP10
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1654388:EL116 RS02070
gene id: 1654388:EL116_RS02070
uniprot id: A0A2K4AJ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1654388:EL116 RS07095
gene id: 1654388:EL116_RS07095
uniprot id: A0A2K4AHU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS08760
gene id: 1654388:EL116_RS08760
uniprot id: A0A2K4AGW2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1654388:EL116 RS08055
gene id: 1654388:EL116_RS08055
uniprot id: A0A3S4NUT1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1654388:EL116 RS10250
gene id: 1654388:EL116_RS10250
uniprot id: A0A2K4AJ62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1654388:EL116 RS07625
gene id: 1654388:EL116_RS07625
uniprot id: A0A2K4AHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1654388:EL116 RS13095
gene id: 1654388:EL116_RS13095
uniprot id: A0A2K4AH80
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1654388:EL116 RS05135
gene id: 1654388:EL116_RS05135
uniprot id: A0A2K4AKY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

1654388:EL116 RS02595
gene id: 1654388:EL116_RS02595
uniprot id: A0A2K4AEP3
names: Caution
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS11965
gene id: 1654388:EL116_RS11965
uniprot id: A0A2K4AFT2
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS11240
gene id: 1654388:EL116_RS11240
uniprot id: A0A077VLD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1654388:EL116 RS13295
gene id: 1654388:EL116_RS13295
uniprot id: A0A2K4AHF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

1654388:EL116 RS06730
gene id: 1654388:EL116_RS06730
uniprot id: A0A2K4AE81
names: Similarity
messages: Belongs to the SecB family.

1654388:EL116 RS13005
gene id: 1654388:EL116_RS13005
uniprot id: A0A2K4AHR5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS09855
gene id: 1654388:EL116_RS09855
uniprot id: A0A2K4AJA3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1654388:EL116 RS06110
gene id: 1654388:EL116_RS06110
uniprot id: A0A2K4ADQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1654388:EL116 RS11280
gene id: 1654388:EL116_RS11280
uniprot id: A0A2K4ALW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1654388:EL116 RS06865
gene id: 1654388:EL116_RS06865
uniprot id: A0A2K4AHR8
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS09245
gene id: 1654388:EL116_RS09245
uniprot id: A0A2K4AF79
names: Function
names: PTM
names: Similarity
messages: Belongs to the type A lantibiotic family.
messages: Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.
messages: Maturation of lantibiotics involves the enzymatic conversion of Thr, and Ser into dehydrated AA and the formation of thioether bonds with cysteine. This is followed by membrane translocation and cleavage of the modified precursor.

1654388:EL116 RS06750
gene id: 1654388:EL116_RS06750
uniprot id: A0A2K4AI03
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS03160
gene id: 1654388:EL116_RS03160
uniprot id: A0A2K4AED5
names: Similarity
messages: Belongs to the DtxR/MntR family.

1654388:EL116 RS06980
gene id: 1654388:EL116_RS06980
uniprot id: A0A2K4AHQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS07725
gene id: 1654388:EL116_RS07725
uniprot id: A0A2K4AG86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1654388:EL116 RS01750
gene id: 1654388:EL116_RS01750
uniprot id: A0A2K4AJ26
names: Function
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.
messages: Reduces FMN, organic nitro compounds and disulfide DTNB. Involved in maintenance of the cellular redox state and the disulfide stress response.

1654388:EL116 RS03295
gene id: 1654388:EL116_RS03295
uniprot id: A0A2K4AKQ7
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS09810
gene id: 1654388:EL116_RS09810
uniprot id: A0A2K4AJA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1654388:EL116 RS05140
gene id: 1654388:EL116_RS05140
uniprot id: A0A2K4AL65
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS04685
gene id: 1654388:EL116_RS04685
uniprot id: A0A2K4AKD7
names: Function
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1654388:EL116 RS13560
gene id: 1654388:EL116_RS13560
uniprot id: A0A2K4ANY4
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1654388:EL116 RS05640
gene id: 1654388:EL116_RS05640
uniprot id: A0A077UI97
names: Function
names: Similarity
messages: Belongs to the thioredoxin family.
messages: Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.

1654388:EL116 RS02660
gene id: 1654388:EL116_RS02660
uniprot id: A0A077VHU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1654388:EL116 RS12100
gene id: 1654388:EL116_RS12100
uniprot id: A0A2K4AGK4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1654388:EL116 RS00605
gene id: 1654388:EL116_RS00605
uniprot id: A0A2K4AMI0
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS02255
gene id: 1654388:EL116_RS02255
uniprot id: A0A2K4AID5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS13010
gene id: 1654388:EL116_RS13010
uniprot id: A0A2K4AHE4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1654388:EL116 RS00490
gene id: 1654388:EL116_RS00490
uniprot id: A0A2K4AFR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1654388:EL116 RS13395
gene id: 1654388:EL116_RS13395
uniprot id: A0A2K4AM97
names: Similarity
messages: Belongs to the serine-rich repeat protein (SRRP) family.

1654388:EL116 RS11265
gene id: 1654388:EL116_RS11265
uniprot id: A0A077V0P8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1654388:EL116 RS09125
gene id: 1654388:EL116_RS09125
uniprot id: A0A2K4AF97
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS03305
gene id: 1654388:EL116_RS03305
uniprot id: A0A2K4AKJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. HrtB subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

1654388:EL116 RS03470
gene id: 1654388:EL116_RS03470
uniprot id: A0A2K4AKK3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Involved in quinolone resistance. May constitute a membrane-associated active efflux pump of hydrophilic quinolones.
messages: Membrane

1654388:EL116 RS05015
gene id: 1654388:EL116_RS05015
uniprot id: A0A2K4AL47
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1654388:EL116 RS04485
gene id: 1654388:EL116_RS04485
uniprot id: A0A2K4AM79
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1654388:EL116 RS08235
gene id: 1654388:EL116_RS08235
uniprot id: A0A2K4AGT9
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1654388:EL116 RS05745
gene id: 1654388:EL116_RS05745
uniprot id: A0A2K4ADM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

1654388:EL116 RS05875
gene id: 1654388:EL116_RS05875
uniprot id: A0A2K4ADQ8
names: Subcellular Location Annotation
messages: Cytoplasm

1654388:EL116 RS06205
gene id: 1654388:EL116_RS06205
uniprot id: A0A2K4ADR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1654388:EL116 RS11270
gene id: 1654388:EL116_RS11270
uniprot id: A0A077W1J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1654388:EL116 RS08185
gene id: 1654388:EL116_RS08185
uniprot id: A0A2K4AGS8
names: Caution
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS03900
gene id: 1654388:EL116_RS03900
uniprot id: A0A2K4AK02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1654388:EL116 RS11700
gene id: 1654388:EL116_RS11700
uniprot id: A0A2K4AFY0
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS04315
gene id: 1654388:EL116_RS04315
uniprot id: A0A448CUS3
names: Subcellular Location Annotation
messages: cell wall

1654388:EL116 RS07595
gene id: 1654388:EL116_RS07595
uniprot id: A0A2K4AHG4
names: Similarity
messages: Belongs to the asparaginase 1 family.

1654388:EL116 RS12885
gene id: 1654388:EL116_RS12885
uniprot id: A0A2K4ALL9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

1654388:EL116 RS08425
gene id: 1654388:EL116_RS08425
uniprot id: A0A2K4AHL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1654388:EL116 RS07685
gene id: 1654388:EL116_RS07685
uniprot id: A0A2K4AG88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1654388:EL116 RS10230
gene id: 1654388:EL116_RS10230
uniprot id: A0A2K4AJB6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS07065
gene id: 1654388:EL116_RS07065
uniprot id: A0A2K4AIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1654388:EL116 RS08305
gene id: 1654388:EL116_RS08305
uniprot id: A0A2K4AGL0
names: Similarity
messages: Belongs to the UPF0473 family.

1654388:EL116 RS08400
gene id: 1654388:EL116_RS08400
uniprot id: A0A2K4AGS6
names: Caution
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS08605
gene id: 1654388:EL116_RS08605
uniprot id: A0A2K4AH13
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS10445
gene id: 1654388:EL116_RS10445
uniprot id: A0A2K4AF61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1654388:EL116 RS13060
gene id: 1654388:EL116_RS13060
uniprot id: A0A2K4AHF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

1654388:EL116 RS01105
gene id: 1654388:EL116_RS01105
uniprot id: A0A2K4AID0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CidB/LrgB family. LrgB subfamily.
messages: Cell membrane
messages: Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
messages: Membrane

1654388:EL116 RS13255
gene id: 1654388:EL116_RS13255
uniprot id: A0A2K4AHB1
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1654388:EL116 RS07915
gene id: 1654388:EL116_RS07915
uniprot id: A0A2K4AGM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1654388:EL116 RS07155
gene id: 1654388:EL116_RS07155
uniprot id: A0A2K4AHY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.
messages: Cytoplasm

1654388:EL116 RS04695
gene id: 1654388:EL116_RS04695
uniprot id: A0A2K4AKK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

1654388:EL116 RS07805
gene id: 1654388:EL116_RS07805
uniprot id: A0A2K4AGD0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1654388:EL116 RS13070
gene id: 1654388:EL116_RS13070
uniprot id: A0A2K4AHB5
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1654388:EL116 RS13670
gene id: 1654388:EL116_RS13670
uniprot id: A0A2K4AP09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

1654388:EL116 RS05675
gene id: 1654388:EL116_RS05675
uniprot id: A0A2K4AEC3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1654388:EL116 RS03325
gene id: 1654388:EL116_RS03325
uniprot id: A0A2K4AKL0
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS10755
gene id: 1654388:EL116_RS10755
uniprot id: A0A2K4AEX1
names: Function
names: Subunit
messages: Homodimer or homotrimer. Seems to be a monomer when not phosphorylated.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1654388:EL116 RS10365
gene id: 1654388:EL116_RS10365
uniprot id: A0A2K4AEP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1654388:EL116 RS01000
gene id: 1654388:EL116_RS01000
uniprot id: A0A2K4AHA8
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS01070
gene id: 1654388:EL116_RS01070
uniprot id: A0A2K4AH16
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Catalyzes the NADPH dependent reduction of D-ribulose 5-phosphate to D-ribitol 5-phosphate.

1654388:EL116 RS01945
gene id: 1654388:EL116_RS01945
uniprot id: A0A2K4AIT9
names: Caution
names: Similarity
messages: Belongs to the staphylococcal tandem lipoprotein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS02895
gene id: 1654388:EL116_RS02895
uniprot id: A0A2K4AEE9
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1654388:EL116 RS04745
gene id: 1654388:EL116_RS04745
uniprot id: A0A2K4AKJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1654388:EL116 RS12170
gene id: 1654388:EL116_RS12170
uniprot id: A0A2K4AFN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin-binding protein Sbi family.
messages: Cell membrane
messages: Membrane
messages: Secreted

1654388:EL116 RS05465
gene id: 1654388:EL116_RS05465
uniprot id: A0A2K4AL53
names: Similarity
messages: Belongs to the UPF0358 family.

1654388:EL116 RS13110
gene id: 1654388:EL116_RS13110
uniprot id: A0A2K4AHA4
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1654388:EL116 RS05555
gene id: 1654388:EL116_RS05555
uniprot id: A0A2K4AL67
names: Subcellular Location Annotation
messages: cell wall

1654388:EL116 RS01780
gene id: 1654388:EL116_RS01780
uniprot id: A0A2K4AJT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1654388:EL116 RS02670
gene id: 1654388:EL116_RS02670
uniprot id: A0A2K4AEJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1654388:EL116 RS09650
gene id: 1654388:EL116_RS09650
uniprot id: A0A2K4AKF0
names: Caution
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS00725
gene id: 1654388:EL116_RS00725
uniprot id: A0A2K4AMP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS11260
gene id: 1654388:EL116_RS11260
uniprot id: A0A077UKF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1654388:EL116 RS02185
gene id: 1654388:EL116_RS02185
uniprot id: A0A2K4AK09
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1654388:EL116 RS04200
gene id: 1654388:EL116_RS04200
uniprot id: A0A2K4ANN2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS12890
gene id: 1654388:EL116_RS12890
uniprot id: A0A2K4ALP0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1654388:EL116 RS12060
gene id: 1654388:EL116_RS12060
uniprot id: A0A2K4AFQ1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1654388:EL116 RS02935
gene id: 1654388:EL116_RS02935
uniprot id: A0A2K4AF92
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS00920
gene id: 1654388:EL116_RS00920
uniprot id: A0A2K4AMN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1654388:EL116 RS06235
gene id: 1654388:EL116_RS06235
uniprot id: A0A2K4ADV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS10600
gene id: 1654388:EL116_RS10600
uniprot id: A0A2K4AF34
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1654388:EL116 RS03050
gene id: 1654388:EL116_RS03050
uniprot id: A0A2K4AER1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1654388:EL116 RS03070
gene id: 1654388:EL116_RS03070
uniprot id: A0A2K4AF70
names: Subcellular Location Annotation
messages: Cell membrane

1654388:EL116 RS00640
gene id: 1654388:EL116_RS00640
uniprot id: A0A2K4AMF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
messages: Belongs to the TRAP family.
messages: Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS09750
gene id: 1654388:EL116_RS09750
uniprot id: A0A2K4AJK9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1654388:EL116 RS11750
gene id: 1654388:EL116_RS11750
uniprot id: A0A2K4AFX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1654388:EL116 RS13365
gene id: 1654388:EL116_RS13365
uniprot id: A0A2K4AHF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Forms a heterotetramer with 2 subunits each of GtfA and GtfB. Part of the accessory SecA2/SecY2 protein translocation apparatus.
messages: Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in the substrate protein. Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon.

1654388:EL116 RS04835
gene id: 1654388:EL116_RS04835
uniprot id: A0A2K4AK84
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1654388:EL116 RS07955
gene id: 1654388:EL116_RS07955
uniprot id: A0A2K4AH95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ComGC family.
messages: Cell membrane
messages: Homodimer.
messages: Required for transformation and DNA binding.

1654388:EL116 RS11070
gene id: 1654388:EL116_RS11070
uniprot id: A0A2K4AJT4
names: Similarity
messages: Belongs to the TPP enzyme family.

1654388:EL116 RS11480
gene id: 1654388:EL116_RS11480
uniprot id: A0A077W0W4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1654388:EL116 RS02685
gene id: 1654388:EL116_RS02685
uniprot id: A0A2K4AEK0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1654388:EL116 RS06380
gene id: 1654388:EL116_RS06380
uniprot id: A0A2K4ADU0
names: Similarity
messages: Belongs to the UPF0045 family.

1654388:EL116 RS06145
gene id: 1654388:EL116_RS06145
uniprot id: A0A0K7NVV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1654388:EL116 RS06955
gene id: 1654388:EL116_RS06955
uniprot id: A0A2K4AHS5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1654388:EL116 RS03715
gene id: 1654388:EL116_RS03715
uniprot id: A0A2K4AJY7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1654388:EL116 RS07385
gene id: 1654388:EL116_RS07385
uniprot id: A0A2K4AHI6
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS05515
gene id: 1654388:EL116_RS05515
uniprot id: A0A2K4AL60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0298 family.
messages: Cytoplasm

1654388:EL116 RS13195
gene id: 1654388:EL116_RS13195
uniprot id: A0A2K4AHD2
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1654388:EL116 RS06930
gene id: 1654388:EL116_RS06930
uniprot id: A0A2K4AHS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1654388:EL116 RS12400
gene id: 1654388:EL116_RS12400
uniprot id: A0A077UQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS10970
gene id: 1654388:EL116_RS10970
uniprot id: A0A2K4AJP6
names: Similarity
messages: Belongs to the aldolase LacD family.

1654388:EL116 RS06945
gene id: 1654388:EL116_RS06945
uniprot id: A0A2K4AI34
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS12715
gene id: 1654388:EL116_RS12715
uniprot id: A0A2K4ALJ2
names: Similarity
messages: Belongs to the nitroreductase family.

1654388:EL116 RS02390
gene id: 1654388:EL116_RS02390
uniprot id: A0A2K4AI37
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1654388:EL116 RS08300
gene id: 1654388:EL116_RS08300
uniprot id: A0A2K4AGJ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS12330
gene id: 1654388:EL116_RS12330
uniprot id: A0A2K4AFJ8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1654388:EL116 RS03625
gene id: 1654388:EL116_RS03625
uniprot id: A0A2K4AJZ3
names: Function
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides.

1654388:EL116 RS11680
gene id: 1654388:EL116_RS11680
uniprot id: A0A2K4AGT3
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS04340
gene id: 1654388:EL116_RS04340
uniprot id: A0A2K4AIG3
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS01745
gene id: 1654388:EL116_RS01745
uniprot id: A0A2K4AJ09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer; disulfide-linked, upon oxidation. 5 homodimers assemble to form a ring-like decamer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1654388:EL116 RS13145
gene id: 1654388:EL116_RS13145
uniprot id: A0A2K4AH90
names: Similarity
messages: Belongs to the MQO family.

1654388:EL116 RS08255
gene id: 1654388:EL116_RS08255
uniprot id: A0A2K4AGJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1654388:EL116 RS08140
gene id: 1654388:EL116_RS08140
uniprot id: A0A2K4AGY2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1654388:EL116 RS00915
gene id: 1654388:EL116_RS00915
uniprot id: A0A2K4AMR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Catalyzes the conversion of pyruvate to formate and acetyl-CoA.
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS11775
gene id: 1654388:EL116_RS11775
uniprot id: A0A2K4AFX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

1654388:EL116 RS08725
gene id: 1654388:EL116_RS08725
uniprot id: A0A2K4AGY6
names: Similarity
messages: Belongs to the universal stress protein A family.

1654388:EL116 RS00080
gene id: 1654388:EL116_RS00080
uniprot id: A0A2K4AP23
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1654388:EL116 RS06265
gene id: 1654388:EL116_RS06265
uniprot id: A0A2K4ADS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1654388:EL116 RS05815
gene id: 1654388:EL116_RS05815
uniprot id: A0A2K4ADP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1654388:EL116 RS01165
gene id: 1654388:EL116_RS01165
uniprot id: A0A2K4AIC0
names: Similarity
messages: Belongs to the peptidase C59 family.

1654388:EL116 RS00495
gene id: 1654388:EL116_RS00495
uniprot id: A0A2K4AEV0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS05285
gene id: 1654388:EL116_RS05285
uniprot id: A0A2K4AL07
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS13435
gene id: 1654388:EL116_RS13435
uniprot id: A0A2K4ALC6
names: Function
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1654388:EL116 RS07335
gene id: 1654388:EL116_RS07335
uniprot id: A0A2K4AHJ7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1654388:EL116 RS07105
gene id: 1654388:EL116_RS07105
uniprot id: A0A2K4AI04
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS03185
gene id: 1654388:EL116_RS03185
uniprot id: A0A2K4AEB0
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1654388:EL116 RS01895
gene id: 1654388:EL116_RS01895
uniprot id: A0A2K4AIV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the staphylococcal/streptococcal toxin family.
messages: Secreted

1654388:EL116 RS06030
gene id: 1654388:EL116_RS06030
uniprot id: A0A077URJ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1654388:EL116 RS05550
gene id: 1654388:EL116_RS05550
uniprot id: A0A077UWR7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1654388:EL116 RS06350
gene id: 1654388:EL116_RS06350
uniprot id: A0A2K4AE05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1654388:EL116 RS00255
gene id: 1654388:EL116_RS00255
uniprot id: A0A2K4ANQ1
names: Caution
names: Similarity
messages: Belongs to the staphylococcal tandem lipoprotein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS00735
gene id: 1654388:EL116_RS00735
uniprot id: A0A2K4ANH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS13125
gene id: 1654388:EL116_RS13125
uniprot id: A0A2K4AHC1
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS07190
gene id: 1654388:EL116_RS07190
uniprot id: A0A2K4AHM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1654388:EL116 RS08315
gene id: 1654388:EL116_RS08315
uniprot id: A0A077W1W9
names: Similarity
messages: Belongs to the UPF0297 family.

1654388:EL116 RS01885
gene id: 1654388:EL116_RS01885
uniprot id: A0A2K4AJV4
names: Similarity
messages: Belongs to the staphylococcal/streptococcal toxin family.

1654388:EL116 RS11195
gene id: 1654388:EL116_RS11195
uniprot id: A0A2K4AM02
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1654388:EL116 RS00205
gene id: 1654388:EL116_RS00205
uniprot id: A0A448CSL2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1654388:EL116 RS07220
gene id: 1654388:EL116_RS07220
uniprot id: A0A2K4AIR4
names: Similarity
messages: Belongs to the acylphosphatase family.

1654388:EL116 RS09975
gene id: 1654388:EL116_RS09975
uniprot id: A0A2K4AJB1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS03770
gene id: 1654388:EL116_RS03770
uniprot id: A0A2K4AK01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1654388:EL116 RS00765
gene id: 1654388:EL116_RS00765
uniprot id: A0A2K4AMN7
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS03250
gene id: 1654388:EL116_RS03250
uniprot id: A0A2K4AEL7
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1654388:EL116 RS01790
gene id: 1654388:EL116_RS01790
uniprot id: W8TP99
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1654388:EL116 RS10070
gene id: 1654388:EL116_RS10070
uniprot id: A0A2K4AK78
names: Similarity
messages: Belongs to the peptidase M20A family.

1654388:EL116 RS10480
gene id: 1654388:EL116_RS10480
uniprot id: A0A2K4AEU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1654388:EL116 RS11325
gene id: 1654388:EL116_RS11325
uniprot id: A0A448CYE9
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS00835
gene id: 1654388:EL116_RS00835
uniprot id: A0A2K4AMP5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1654388:EL116 RS10330
gene id: 1654388:EL116_RS10330
uniprot id: A0A077W1R3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system. Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity.
messages: Belongs to the MazE/EndoAI family.

1654388:EL116 RS03880
gene id: 1654388:EL116_RS03880
uniprot id: A0A2K4AK10
names: Caution
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS07305
gene id: 1654388:EL116_RS07305
uniprot id: A0A2K4AHZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41A family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS12810
gene id: 1654388:EL116_RS12810
uniprot id: A0A2K4ALM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CidA/LrgA family. CidA subfamily.
messages: Cell membrane
messages: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins. When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential.
messages: Membrane

1654388:EL116 RS05360
gene id: 1654388:EL116_RS05360
uniprot id: A0A2K4AL24
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1654388:EL116 RS00565
gene id: 1654388:EL116_RS00565
uniprot id: A0A2K4AMH3
names: Similarity
messages: Belongs to the CpsD/CapB family.

1654388:EL116 RS01915
gene id: 1654388:EL116_RS01915
uniprot id: A0A2K4AIT4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1654388:EL116 RS11495
gene id: 1654388:EL116_RS11495
uniprot id: A0A2K4ALS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1654388:EL116 RS01665
gene id: 1654388:EL116_RS01665
uniprot id: A0A077ULD7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1654388:EL116 RS07235
gene id: 1654388:EL116_RS07235
uniprot id: A0A2K4AHK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1654388:EL116 RS12910
gene id: 1654388:EL116_RS12910
uniprot id: A0A2K4AH20
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1654388:EL116 RS07320
gene id: 1654388:EL116_RS07320
uniprot id: A0A2K4AHL0
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS08745
gene id: 1654388:EL116_RS08745
uniprot id: A0A077VQY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1654388:EL116 RS01785
gene id: 1654388:EL116_RS01785
uniprot id: A0A2K4AIQ0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1654388:EL116 RS06695
gene id: 1654388:EL116_RS06695
uniprot id: A0A2K4AE08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

1654388:EL116 RS02955
gene id: 1654388:EL116_RS02955
uniprot id: A0A2K4AEE8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS04095
gene id: 1654388:EL116_RS04095
uniprot id: A0A2K4ANQ4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS02855
gene id: 1654388:EL116_RS02855
uniprot id: A0A2K4AEJ9
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS10010
gene id: 1654388:EL116_RS10010
uniprot id: A0A2K4AJ67
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS12795
gene id: 1654388:EL116_RS12795
uniprot id: A0A2K4ALN8
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS10615
gene id: 1654388:EL116_RS10615
uniprot id: W8TRN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1654388:EL116 RS02080
gene id: 1654388:EL116_RS02080
uniprot id: A0A2K4AIV5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1654388:EL116 RS01065
gene id: 1654388:EL116_RS01065
uniprot id: A0A2K4AH35
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
messages: Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS03745
gene id: 1654388:EL116_RS03745
uniprot id: A0A2K4AK71
names: Similarity
messages: Belongs to the IMPACT family.

1654388:EL116 RS13045
gene id: 1654388:EL116_RS13045
uniprot id: A0A2K4AI61
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS05630
gene id: 1654388:EL116_RS05630
uniprot id: A0A2K4ADG4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

1654388:EL116 RS13170
gene id: 1654388:EL116_RS13170
uniprot id: A0A2K4AHL6
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

1654388:EL116 RS13795
gene id: 1654388:EL116_RS13795
uniprot id: A0A2K4AJK8
names: Similarity
names: Subunit
messages: Belongs to the LacAB/RpiB family.
messages: Heteromultimeric protein consisting of LacA and LacB.

1654388:EL116 RS09645
gene id: 1654388:EL116_RS09645
uniprot id: A0A077UW59
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

1654388:EL116 RS06285
gene id: 1654388:EL116_RS06285
uniprot id: A0A2K4ADT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1654388:EL116 RS06225
gene id: 1654388:EL116_RS06225
uniprot id: A0A2K4AEL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1654388:EL116 RS00135
gene id: 1654388:EL116_RS00135
uniprot id: A0A2K4AMR0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1654388:EL116 RS06155
gene id: 1654388:EL116_RS06155
uniprot id: A0A2K4ADS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1654388:EL116 RS10495
gene id: 1654388:EL116_RS10495
uniprot id: A0A2K4AF71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1654388:EL116 RS09805
gene id: 1654388:EL116_RS09805
uniprot id: A0A2K4AJB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1654388:EL116 RS02905
gene id: 1654388:EL116_RS02905
uniprot id: A0A077UYG7
names: Similarity
messages: Belongs to the UPF0741 family.

1654388:EL116 RS07395
gene id: 1654388:EL116_RS07395
uniprot id: A0A2K4AHI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer.

1654388:EL116 RS03525
gene id: 1654388:EL116_RS03525
uniprot id: A0A2K4AKU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS13205
gene id: 1654388:EL116_RS13205
uniprot id: A0A2K4AHA3
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS08090
gene id: 1654388:EL116_RS08090
uniprot id: A0A2K4AGL9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1654388:EL116 RS03670
gene id: 1654388:EL116_RS03670
uniprot id: A0A2K4AJY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1654388:EL116 RS10890
gene id: 1654388:EL116_RS10890
uniprot id: A0A2K4AJX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1654388:EL116 RS02705
gene id: 1654388:EL116_RS02705
uniprot id: A0A2K4AES8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1654388:EL116 RS05270
gene id: 1654388:EL116_RS05270
uniprot id: A0A2K4AL38
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1654388:EL116 RS04925
gene id: 1654388:EL116_RS04925
uniprot id: A0A2K4AK89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS05410
gene id: 1654388:EL116_RS05410
uniprot id: A0A2K4AL30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS02815
gene id: 1654388:EL116_RS02815
uniprot id: A0A2K4AEQ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1654388:EL116 RS08665
gene id: 1654388:EL116_RS08665
uniprot id: A0A2K4AH66
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1654388:EL116 RS08830
gene id: 1654388:EL116_RS08830
uniprot id: A0A2K4AFP3
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS08950
gene id: 1654388:EL116_RS08950
uniprot id: A0A2K4AFA5
names: Function
names: Similarity
names: Subunit
messages: Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are essential bacterial cell wall components.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1654388:EL116 RS00815
gene id: 1654388:EL116_RS00815
uniprot id: A0A2K4AMP6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1654388:EL116 RS08395
gene id: 1654388:EL116_RS08395
uniprot id: A0A2K4AH14
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS02395
gene id: 1654388:EL116_RS02395
uniprot id: A0A2K4AHX3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. Can also catalyze the epimerization of carbon 2' of dihydroneopterin to dihydromonapterin.

1654388:EL116 RS10210
gene id: 1654388:EL116_RS10210
uniprot id: A0A2K4AJM8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS07930
gene id: 1654388:EL116_RS07930
uniprot id: A0A2K4AGC5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS01075
gene id: 1654388:EL116_RS01075
uniprot id: A0A077W228
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1654388:EL116 RS04915
gene id: 1654388:EL116_RS04915
uniprot id: A0A2K4AK59
names: Similarity
messages: Belongs to the UPF0738 family.

1654388:EL116 RS04810
gene id: 1654388:EL116_RS04810
uniprot id: A0A2K4AK93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1654388:EL116 RS07350
gene id: 1654388:EL116_RS07350
uniprot id: A0A2K4AHQ5
names: Similarity
messages: Belongs to the CvfC family.

1654388:EL116 RS06710
gene id: 1654388:EL116_RS06710
uniprot id: A0A2K4ADZ9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS01615
gene id: 1654388:EL116_RS01615
uniprot id: A0A2K4AIR3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1654388:EL116 RS01525
gene id: 1654388:EL116_RS01525
uniprot id: A0A2K4AIK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1654388:EL116 RS05730
gene id: 1654388:EL116_RS05730
uniprot id: A0A2K4ADH9
names: Similarity
messages: Belongs to the staphylococcal/streptococcal toxin family.

1654388:EL116 RS09110
gene id: 1654388:EL116_RS09110
uniprot id: A0A2K4AF76
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1654388:EL116 RS05920
gene id: 1654388:EL116_RS05920
uniprot id: A0A2K4ADP4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1654388:EL116 RS09675
gene id: 1654388:EL116_RS09675
uniprot id: A0A2K4AJE3
names: Function
names: Subcellular Location Annotation
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.
messages: Membrane

1654388:EL116 RS10530
gene id: 1654388:EL116_RS10530
uniprot id: A0A2K4AEV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1654388:EL116 RS00050
gene id: 1654388:EL116_RS00050
uniprot id: A0A2K4ANZ5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS05490
gene id: 1654388:EL116_RS05490
uniprot id: A0A2K4ALD5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

1654388:EL116 RS05860
gene id: 1654388:EL116_RS05860
uniprot id: W8UBH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1654388:EL116 RS01620
gene id: 1654388:EL116_RS01620
uniprot id: A0A2K4AIY4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1654388:EL116 RS07465
gene id: 1654388:EL116_RS07465
uniprot id: A0A2K4AHW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1654388:EL116 RS06105
gene id: 1654388:EL116_RS06105
uniprot id: A0A2K4ADP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1654388:EL116 RS02250
gene id: 1654388:EL116_RS02250
uniprot id: A0A2K4AIG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1654388:EL116 RS00335
gene id: 1654388:EL116_RS00335
uniprot id: A0A2K4AMZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1654388:EL116 RS05095
gene id: 1654388:EL116_RS05095
uniprot id: A0A2K4AKW7
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS06885
gene id: 1654388:EL116_RS06885
uniprot id: A0A2K4AI44
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1654388:EL116 RS08470
gene id: 1654388:EL116_RS08470
uniprot id: A0A2K4AGM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1654388:EL116 RS02540
gene id: 1654388:EL116_RS02540
uniprot id: A0A2K4AFH0
names: Similarity
messages: Belongs to the ClpA/ClpB family. ClpC subfamily.

1654388:EL116 RS06840
gene id: 1654388:EL116_RS06840
uniprot id: A0A2K4AHU3
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1654388:EL116 RS03910
gene id: 1654388:EL116_RS03910
uniprot id: A0A2K4APN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1654388:EL116 RS05800
gene id: 1654388:EL116_RS05800
uniprot id: A0A2K4AEE3
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

1654388:EL116 RS06065
gene id: 1654388:EL116_RS06065
uniprot id: A0A077VGP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1654388:EL116 RS07505
gene id: 1654388:EL116_RS07505
uniprot id: A0A2K4AHT6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS12965
gene id: 1654388:EL116_RS12965
uniprot id: A0A2K4AHA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase family. IsaA subfamily.
messages: Is able to cleave peptidoglycan.
messages: Secreted

1654388:EL116 RS07015
gene id: 1654388:EL116_RS07015
uniprot id: A0A2K4AIU9
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1654388:EL116 RS10790
gene id: 1654388:EL116_RS10790
uniprot id: A0A2K4AF82
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1654388:EL116 RS07205
gene id: 1654388:EL116_RS07205
uniprot id: A0A077VUP9
names: Subcellular Location Annotation
messages: Cytoplasm

1654388:EL116 RS04520
gene id: 1654388:EL116_RS04520
uniprot id: A0A077VXX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1654388:EL116 RS13515
gene id: 1654388:EL116_RS13515
uniprot id: A0A2K4APR7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1654388:EL116 RS07430
gene id: 1654388:EL116_RS07430
uniprot id: A0A077W0F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

1654388:EL116 RS05965
gene id: 1654388:EL116_RS05965
uniprot id: A0A2K4ADL4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS03635
gene id: 1654388:EL116_RS03635
uniprot id: A0A2K4AJV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS00620
gene id: 1654388:EL116_RS00620
uniprot id: A0A2K4AMG3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1654388:EL116 RS12970
gene id: 1654388:EL116_RS12970
uniprot id: A0A2K4AH38
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS08555
gene id: 1654388:EL116_RS08555
uniprot id: A0A2K4AGV6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1654388:EL116 RS00585
gene id: 1654388:EL116_RS00585
uniprot id: A0A2K4AMK7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS05145
gene id: 1654388:EL116_RS05145
uniprot id: A0A2K4AL58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I57 (SspC) family.
messages: Cytoplasm
messages: Forms a stable non-covalent complex with prematurely activated/folded SspB.
messages: Specifically inhibits the cysteine protease staphopain B (SspB) by blocking the active site of the enzyme. Probably required to protect cytoplasmic proteins from being degraded by prematurely activated/folded prostaphopain B. Also involved in growth capacity, viability and bacterial morphology.

1654388:EL116 RS07850
gene id: 1654388:EL116_RS07850
uniprot id: A0A2K4AH74
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1654388:EL116 RS06215
gene id: 1654388:EL116_RS06215
uniprot id: A0A2K4ADS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1654388:EL116 RS08110
gene id: 1654388:EL116_RS08110
uniprot id: A0A077ULD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1654388:EL116 RS11250
gene id: 1654388:EL116_RS11250
uniprot id: A0A077V4G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1654388:EL116 RS07115
gene id: 1654388:EL116_RS07115
uniprot id: A0A2K4AHP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1654388:EL116 RS03640
gene id: 1654388:EL116_RS03640
uniprot id: A0A2K4AJW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1654388:EL116 RS08750
gene id: 1654388:EL116_RS08750
uniprot id: A0A2K4AGS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1654388:EL116 RS12315
gene id: 1654388:EL116_RS12315
uniprot id: A0A2K4AFJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS08530
gene id: 1654388:EL116_RS08530
uniprot id: A0A2K4AHN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS06075
gene id: 1654388:EL116_RS06075
uniprot id: A0A077UUW2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1654388:EL116 RS08815
gene id: 1654388:EL116_RS08815
uniprot id: A0A2K4AFD7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1654388:EL116 RS10305
gene id: 1654388:EL116_RS10305
uniprot id: A0A2K4AEN8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

1654388:EL116 RS11225
gene id: 1654388:EL116_RS11225
uniprot id: A0A2K4AM03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1654388:EL116 RS07785
gene id: 1654388:EL116_RS07785
uniprot id: A0A2K4AGA6
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS05680
gene id: 1654388:EL116_RS05680
uniprot id: A0A2K4ADH4
names: Subcellular Location Annotation
messages: Secreted

1654388:EL116 RS00460
gene id: 1654388:EL116_RS00460
uniprot id: A0A2K4AF24
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS01330
gene id: 1654388:EL116_RS01330
uniprot id: A0A2K4AIM5
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS03550
gene id: 1654388:EL116_RS03550
uniprot id: A0A2K4AJX1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS13600
gene id: 1654388:EL116_RS13600
uniprot id: A0A2K4ANZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1654388:EL116 RS07160
gene id: 1654388:EL116_RS07160
uniprot id: A0A2K4AHR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS06305
gene id: 1654388:EL116_RS06305
uniprot id: A0A3S4Q1H3
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1654388:EL116 RS01970
gene id: 1654388:EL116_RS01970
uniprot id: A0A448CTI3
names: Similarity
messages: Belongs to the staphylococcal tandem lipoprotein family.

1654388:EL116 RS08135
gene id: 1654388:EL116_RS08135
uniprot id: A0A2K4AGR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1654388:EL116 RS05950
gene id: 1654388:EL116_RS05950
uniprot id: A0A2K4ADM9
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1654388:EL116 RS06275
gene id: 1654388:EL116_RS06275
uniprot id: A0A2K4ADS4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1654388:EL116 RS09945
gene id: 1654388:EL116_RS09945
uniprot id: A0A2K4AJA8
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS08005
gene id: 1654388:EL116_RS08005
uniprot id: A0A2K4AHD7
names: Similarity
messages: Belongs to the transpeptidase family.

1654388:EL116 RS13345
gene id: 1654388:EL116_RS13345
uniprot id: A0A2K4AHB3
names: Similarity
messages: In the N-terminal section; belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1654388:EL116 RS12635
gene id: 1654388:EL116_RS12635
uniprot id: A0A2K4AGD1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS11215
gene id: 1654388:EL116_RS11215
uniprot id: W8U8T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1654388:EL116 RS12765
gene id: 1654388:EL116_RS12765
uniprot id: A0A077UNB2
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS07225
gene id: 1654388:EL116_RS07225
uniprot id: A0A2K4AHS8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS07880
gene id: 1654388:EL116_RS07880
uniprot id: A0A2K4AGB5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1654388:EL116 RS01170
gene id: 1654388:EL116_RS01170
uniprot id: A0A2K4AIB1
names: Similarity
messages: Belongs to the peptidase M23B family.

1654388:EL116 RS10380
gene id: 1654388:EL116_RS10380
uniprot id: A0A2K4AEU5
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS03760
gene id: 1654388:EL116_RS03760
uniprot id: A0A2K4AJY8
names: Function
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1654388:EL116 RS02295
gene id: 1654388:EL116_RS02295
uniprot id: A0A2K4AI55
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1654388:EL116 RS01025
gene id: 1654388:EL116_RS01025
uniprot id: A0A2K4AH21
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS03400
gene id: 1654388:EL116_RS03400
uniprot id: A0A2K4AKT0
names: Similarity
messages: Belongs to the UPF0178 family.

1654388:EL116 RS05765
gene id: 1654388:EL116_RS05765
uniprot id: A0A2K4ADJ9
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS12280
gene id: 1654388:EL116_RS12280
uniprot id: A0A2K4AFK6
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS03845
gene id: 1654388:EL116_RS03845
uniprot id: A0A2K4AK90
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS00630
gene id: 1654388:EL116_RS00630
uniprot id: A0A2K4ANB2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1654388:EL116 RS06900
gene id: 1654388:EL116_RS06900
uniprot id: A0A2K4AHV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1654388:EL116 RS05205
gene id: 1654388:EL116_RS05205
uniprot id: A0A2K4AKY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS10575
gene id: 1654388:EL116_RS10575
uniprot id: A0A2K4AET1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1654388:EL116 RS10865
gene id: 1654388:EL116_RS10865
uniprot id: A0A2K4AJR7
names: Similarity
messages: Belongs to the UDPGP type 1 family.

1654388:EL116 RS01575
gene id: 1654388:EL116_RS01575
uniprot id: A0A2K4AIR2
names: Subcellular Location Annotation
messages: Cell membrane

1654388:EL116 RS04740
gene id: 1654388:EL116_RS04740
uniprot id: A0A2K4AKD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

1654388:EL116 RS09490
gene id: 1654388:EL116_RS09490
uniprot id: A0A2K4AF20
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS02535
gene id: 1654388:EL116_RS02535
uniprot id: A0A2K4AF22
names: Caution
names: Function
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS06795
gene id: 1654388:EL116_RS06795
uniprot id: A0A2K4AHU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS05355
gene id: 1654388:EL116_RS05355
uniprot id: A0A077V016
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1654388:EL116 RS10090
gene id: 1654388:EL116_RS10090
uniprot id: A0A2K4AJ54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1654388:EL116 RS12600
gene id: 1654388:EL116_RS12600
uniprot id: A0A2K4AG20
names: Similarity
messages: Belongs to the FGGY kinase family.

1654388:EL116 RS01145
gene id: 1654388:EL116_RS01145
uniprot id: A0A2K4AII6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS04755
gene id: 1654388:EL116_RS04755
uniprot id: A0A2K4AKA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0344 family.
messages: Cell membrane

1654388:EL116 RS06080
gene id: 1654388:EL116_RS06080
uniprot id: A0A2K4ADV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1654388:EL116 RS06990
gene id: 1654388:EL116_RS06990
uniprot id: A0A2K4AHW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1654388:EL116 RS11890
gene id: 1654388:EL116_RS11890
uniprot id: A0A2K4AGP3
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS09020
gene id: 1654388:EL116_RS09020
uniprot id: A0A2K4AFG1
names: Cofactor
messages: Binds 1 FAD per subunit.

1654388:EL116 RS06045
gene id: 1654388:EL116_RS06045
uniprot id: A0A2K4ADN0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1654388:EL116 RS06445
gene id: 1654388:EL116_RS06445
uniprot id: A0A2K4ADW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1654388:EL116 RS10040
gene id: 1654388:EL116_RS10040
uniprot id: A0A2K4AJ64
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS02525
gene id: 1654388:EL116_RS02525
uniprot id: A0A2K4AEQ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the CtsR family.
messages: Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS01960
gene id: 1654388:EL116_RS01960
uniprot id: A0A2K4AJ63
names: Similarity
messages: Belongs to the staphylococcal tandem lipoprotein family.

1654388:EL116 RS05700
gene id: 1654388:EL116_RS05700
uniprot id: A0A2K4ADJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCIN family.
messages: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses.
messages: Secreted

1654388:EL116 RS07040
gene id: 1654388:EL116_RS07040
uniprot id: A0A2K4AHV6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS07975
gene id: 1654388:EL116_RS07975
uniprot id: A0A2K4AGV4
names: Similarity
messages: Belongs to the UPF0045 family.

1654388:EL116 RS00990
gene id: 1654388:EL116_RS00990
uniprot id: A0A2K4AH72
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS02335
gene id: 1654388:EL116_RS02335
uniprot id: A0A2K4AI59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1654388:EL116 RS09365
gene id: 1654388:EL116_RS09365
uniprot id: A0A2K4AFL2
names: Similarity
messages: Belongs to the TRAP family.

1654388:EL116 RS07995
gene id: 1654388:EL116_RS07995
uniprot id: A0A2K4AGE9
names: Caution
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS13270
gene id: 1654388:EL116_RS13270
uniprot id: A0A2K4AHN6
names: Similarity
messages: Belongs to the esterase D family.

1654388:EL116 RS10410
gene id: 1654388:EL116_RS10410
uniprot id: A0A2K4AES0
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS08970
gene id: 1654388:EL116_RS08970
uniprot id: A0A2K4AFH1
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS12225
gene id: 1654388:EL116_RS12225
uniprot id: A0A2K4AFN0
names: Function
names: Subcellular Location Annotation
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.
messages: Membrane

1654388:EL116 RS12220
gene id: 1654388:EL116_RS12220
uniprot id: A0A2K4AFM0
names: Function
names: Subcellular Location Annotation
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.
messages: Membrane

1654388:EL116 RS11075
gene id: 1654388:EL116_RS11075
uniprot id: A0A2K4AJJ6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS12845
gene id: 1654388:EL116_RS12845
uniprot id: A0A2K4ALS8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1654388:EL116 RS05955
gene id: 1654388:EL116_RS05955
uniprot id: A0A2K4ADL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1654388:EL116 RS08645
gene id: 1654388:EL116_RS08645
uniprot id: A0A2K4AGU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1654388:EL116 RS11510
gene id: 1654388:EL116_RS11510
uniprot id: A0A2K4AM09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1654388:EL116 RS01755
gene id: 1654388:EL116_RS01755
uniprot id: A0A2K4AIU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1654388:EL116 RS07800
gene id: 1654388:EL116_RS07800
uniprot id: A0A2K4AH64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1654388:EL116 RS00705
gene id: 1654388:EL116_RS00705
uniprot id: A0A2K4AMJ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS06950
gene id: 1654388:EL116_RS06950
uniprot id: A0A2K4AHU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein.
messages: Monomer.

1654388:EL116 RS10235
gene id: 1654388:EL116_RS10235
uniprot id: A0A2K4AJ31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1654388:EL116 RS03945
gene id: 1654388:EL116_RS03945
uniprot id: A0A2K4ANW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1654388:EL116 RS10685
gene id: 1654388:EL116_RS10685
uniprot id: A0A2K4AF10
names: Similarity
messages: Belongs to the Dps family.

1654388:EL116 RS05625
gene id: 1654388:EL116_RS05625
uniprot id: A0A2K4AEB4
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS09420
gene id: 1654388:EL116_RS09420
uniprot id: A0A2K4AFD8
names: Similarity
messages: Belongs to the UPF0754 family.

1654388:EL116 RS13020
gene id: 1654388:EL116_RS13020
uniprot id: A0A2K4AHB0
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

1654388:EL116 RS03170
gene id: 1654388:EL116_RS03170
uniprot id: A0A2K4AF50
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1654388:EL116 RS02095
gene id: 1654388:EL116_RS02095
uniprot id: A0A2K4AJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1654388:EL116 RS13665
gene id: 1654388:EL116_RS13665
uniprot id: A0A2K4AP04
names: Similarity
messages: Belongs to the ParB family.

1654388:EL116 RS07820
gene id: 1654388:EL116_RS07820
uniprot id: A0A2K4AGS5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1654388:EL116 RS08730
gene id: 1654388:EL116_RS08730
uniprot id: A0A2K4AGT1
names: Similarity
messages: Belongs to the UPF0173 family.

1654388:EL116 RS05240
gene id: 1654388:EL116_RS05240
uniprot id: A0A2K4AL90
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1654388:EL116 RS04445
gene id: 1654388:EL116_RS04445
uniprot id: A0A2K4AM38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS01965
gene id: 1654388:EL116_RS01965
uniprot id: A0A2K4AIY9
names: Similarity
messages: Belongs to the staphylococcal tandem lipoprotein family.

1654388:EL116 RS05810
gene id: 1654388:EL116_RS05810
uniprot id: A0A2K4ADN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1654388:EL116 RS06250
gene id: 1654388:EL116_RS06250
uniprot id: A0A2K4AE57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1654388:EL116 RS07680
gene id: 1654388:EL116_RS07680
uniprot id: A0A2K4AG85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1654388:EL116 RS03795
gene id: 1654388:EL116_RS03795
uniprot id: A0A2K4AK80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1654388:EL116 RS11755
gene id: 1654388:EL116_RS11755
uniprot id: A0A2K4AFV0
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS08680
gene id: 1654388:EL116_RS08680
uniprot id: A0A2K4AGS7
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1654388:EL116 RS00250
gene id: 1654388:EL116_RS00250
uniprot id: A0A2K4AMW1
names: Similarity
messages: Belongs to the staphylococcal tandem lipoprotein family.

1654388:EL116 RS02365
gene id: 1654388:EL116_RS02365
uniprot id: A0A2K4AIB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.

1654388:EL116 RS13955
gene id: 1654388:EL116_RS13955
uniprot id: A0A2K4AK74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the delta-lysin family.
messages: Cell membrane
messages: Host cell membrane
messages: Lyses erythrocytes and many other mammalian cells.
messages: Membrane
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS05865
gene id: 1654388:EL116_RS05865
uniprot id: A0A2K4ADJ7
names: Similarity
messages: Belongs to the YggT family.

1654388:EL116 RS00405
gene id: 1654388:EL116_RS00405
uniprot id: A0A2K4AMV3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1654388:EL116 RS09470
gene id: 1654388:EL116_RS09470
uniprot id: A0A2K4AFC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1654388:EL116 RS09290
gene id: 1654388:EL116_RS09290
uniprot id: A0A2K4AG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the staphylococcal/streptococcal toxin family.
messages: Secreted

1654388:EL116 RS07865
gene id: 1654388:EL116_RS07865
uniprot id: A0A2K4AGL8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1654388:EL116 RS01240
gene id: 1654388:EL116_RS01240
uniprot id: A0A2K4AIK7
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

1654388:EL116 RS04350
gene id: 1654388:EL116_RS04350
uniprot id: A0A2K4AI93
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS12540
gene id: 1654388:EL116_RS12540
uniprot id: A0A2K4AFG5
names: Subcellular Location Annotation
messages: Cell membrane

1654388:EL116 RS10540
gene id: 1654388:EL116_RS10540
uniprot id: A0A2K4AEX4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1654388:EL116 RS01725
gene id: 1654388:EL116_RS01725
uniprot id: A0A2K4AJS7
names: Subcellular Location Annotation
messages: Cell membrane

1654388:EL116 RS11275
gene id: 1654388:EL116_RS11275
uniprot id: A0A2K4ALZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1654388:EL116 RS04500
gene id: 1654388:EL116_RS04500
uniprot id: A0A2K4AM66
names: Function
names: Similarity
messages: Belongs to the nitronate monooxygenase family. NMO class I subfamily.
messages: Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. Acts on propionate 3-nitronate (P3N), the presumed physiological substrate. Probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism.

1654388:EL116 RS09905
gene id: 1654388:EL116_RS09905
uniprot id: A0A2K4AJH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C47 family.
messages: Secreted

1654388:EL116 RS10745
gene id: 1654388:EL116_RS10745
uniprot id: A0A2K4AFD2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS11355
gene id: 1654388:EL116_RS11355
uniprot id: A0A2K4ALZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1654388:EL116 RS13175
gene id: 1654388:EL116_RS13175
uniprot id: A0A2K4AHC9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1654388:EL116 RS08540
gene id: 1654388:EL116_RS08540
uniprot id: A0A2K4AGS9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1654388:EL116 RS04655
gene id: 1654388:EL116_RS04655
uniprot id: A0A2K4ALC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS02510
gene id: 1654388:EL116_RS02510
uniprot id: A0A2K4AER5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1654388:EL116 RS12210
gene id: 1654388:EL116_RS12210
uniprot id: A0A2K4AGI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS07965
gene id: 1654388:EL116_RS07965
uniprot id: A0A2K4AGH2
names: Similarity
messages: Belongs to the GSP E family.

1654388:EL116 RS03930
gene id: 1654388:EL116_RS03930
uniprot id: A0A077W084
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1654388:EL116 RS01985
gene id: 1654388:EL116_RS01985
uniprot id: A0A2K4AIZ2
names: Caution
names: Similarity
messages: Belongs to the staphylococcal tandem lipoprotein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS00860
gene id: 1654388:EL116_RS00860
uniprot id: A0A2K4AMS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

1654388:EL116 RS11255
gene id: 1654388:EL116_RS11255
uniprot id: A0A077UU26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1654388:EL116 RS06340
gene id: 1654388:EL116_RS06340
uniprot id: A0A2K4ADU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1654388:EL116 RS05900
gene id: 1654388:EL116_RS05900
uniprot id: A0A2K4ADL8
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1654388:EL116 RS08320
gene id: 1654388:EL116_RS08320
uniprot id: A0A2K4AHJ8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS11950
gene id: 1654388:EL116_RS11950
uniprot id: A0A2K4AGN5
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS07485
gene id: 1654388:EL116_RS07485
uniprot id: A0A2K4AIL1
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS04405
gene id: 1654388:EL116_RS04405
uniprot id: A0A2K4AIE2
names: Similarity
messages: Belongs to the nitroreductase family.

1654388:EL116 RS08035
gene id: 1654388:EL116_RS08035
uniprot id: A0A2K4AGE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

1654388:EL116 RS13460
gene id: 1654388:EL116_RS13460
uniprot id: A0A077W1H7
names: Function
names: Subunit
messages: Homodimer.
messages: Represses transcription of the icaADBC operon necessary for biofilm production.

1654388:EL116 RS05995
gene id: 1654388:EL116_RS05995
uniprot id: A0A2K4ADM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1654388:EL116 RS08000
gene id: 1654388:EL116_RS08000
uniprot id: A0A077UXT4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1654388:EL116 RS00055
gene id: 1654388:EL116_RS00055
uniprot id: A0A2K4AP55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1654388:EL116 RS02745
gene id: 1654388:EL116_RS02745
uniprot id: A0A3S4NJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serine-aspartate repeat-containing protein (SDr) family.
messages: cell wall

1654388:EL116 RS09865
gene id: 1654388:EL116_RS09865
uniprot id: A0A2K4AKB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS08355
gene id: 1654388:EL116_RS08355
uniprot id: A0A2K4AGM0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1654388:EL116 RS07515
gene id: 1654388:EL116_RS07515
uniprot id: A0A2K4AHG6
names: Caution
names: Similarity
messages: Belongs to the UPF0302 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS00775
gene id: 1654388:EL116_RS00775
uniprot id: A0A2K4AML1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1654388:EL116 RS07020
gene id: 1654388:EL116_RS07020
uniprot id: A0A2K4AHW3
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1654388:EL116 RS05290
gene id: 1654388:EL116_RS05290
uniprot id: A0A2K4ALA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS03415
gene id: 1654388:EL116_RS03415
uniprot id: A0A2K4AKI3
names: Function
names: Subcellular Location Annotation
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.
messages: Membrane

1654388:EL116 RS01010
gene id: 1654388:EL116_RS01010
uniprot id: A0A448CT44
names: Function
names: Subunit
messages: Homodimer or homotrimer. Seems to be a monomer when not phosphorylated.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1654388:EL116 RS07580
gene id: 1654388:EL116_RS07580
uniprot id: A0A2K4AHV0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1654388:EL116 RS08010
gene id: 1654388:EL116_RS08010
uniprot id: A0A2K4AGH0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1654388:EL116 RS13565
gene id: 1654388:EL116_RS13565
uniprot id: A0A2K4APS7
names: Similarity
messages: Belongs to the UPF0312 family.

1654388:EL116 RS04830
gene id: 1654388:EL116_RS04830
uniprot id: A0A2K4AK87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS12195
gene id: 1654388:EL116_RS12195
uniprot id: A0A2K4AFY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BioW family.
messages: Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
messages: Homodimer.

1654388:EL116 RS03430
gene id: 1654388:EL116_RS03430
uniprot id: A0A2K4AKN2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1654388:EL116 RS12135
gene id: 1654388:EL116_RS12135
uniprot id: A0A2K4AG54
names: Subcellular Location Annotation
messages: Cell membrane

1654388:EL116 RS07590
gene id: 1654388:EL116_RS07590
uniprot id: A0A2K4AHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1654388:EL116 RS08635
gene id: 1654388:EL116_RS08635
uniprot id: A0A2K4AGQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1654388:EL116 RS01400
gene id: 1654388:EL116_RS01400
uniprot id: A0A2K4AIM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1654388:EL116 RS05575
gene id: 1654388:EL116_RS05575
uniprot id: A0A2K4AM55
names: Similarity
messages: Belongs to the bacterial solute-binding protein 8 family.

1654388:EL116 RS10455
gene id: 1654388:EL116_RS10455
uniprot id: A0A2K4AEQ9
names: Similarity
messages: Belongs to the ThiD family.

1654388:EL116 RS10375
gene id: 1654388:EL116_RS10375
uniprot id: A0A2K4AER6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS03595
gene id: 1654388:EL116_RS03595
uniprot id: A0A2K4AK41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate. Is required for staphylococcal growth and cell division process.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS04700
gene id: 1654388:EL116_RS04700
uniprot id: A0A2K4AKB1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1654388:EL116 RS08440
gene id: 1654388:EL116_RS08440
uniprot id: A0A2K4AGX6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1654388:EL116 RS08430
gene id: 1654388:EL116_RS08430
uniprot id: A0A2K4AGQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1654388:EL116 RS12905
gene id: 1654388:EL116_RS12905
uniprot id: A0A0U1MF20
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

1654388:EL116 RS11390
gene id: 1654388:EL116_RS11390
uniprot id: A0A2K4ALS6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1654388:EL116 RS02340
gene id: 1654388:EL116_RS02340
uniprot id: A0A2K4AI48
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS04420
gene id: 1654388:EL116_RS04420
uniprot id: A0A2K4AIE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1654388:EL116 RS05905
gene id: 1654388:EL116_RS05905
uniprot id: A0A2K4ADK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1654388:EL116 RS08785
gene id: 1654388:EL116_RS08785
uniprot id: A0A2K4AFH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

1654388:EL116 RS12010
gene id: 1654388:EL116_RS12010
uniprot id: A0A2K4AFR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane
messages: Probably required for nitrate uptake under anoxic conditions. Also possibly involved in excretion of nitrite produced by the dissimilatory reduction of nitrate.

1654388:EL116 RS03340
gene id: 1654388:EL116_RS03340
uniprot id: A0A2K4AKI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

1654388:EL116 RS05740
gene id: 1654388:EL116_RS05740
uniprot id: A0A2K4ADI4
names: Similarity
messages: Belongs to the staphylococcal/streptococcal toxin family.

1654388:EL116 RS10940
gene id: 1654388:EL116_RS10940
uniprot id: A0A2K4AJW7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1654388:EL116 RS11155
gene id: 1654388:EL116_RS11155
uniprot id: W8TRE8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1654388:EL116 RS10500
gene id: 1654388:EL116_RS10500
uniprot id: A0A2K4AEY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1654388:EL116 RS07340
gene id: 1654388:EL116_RS07340
uniprot id: A0A2K4AHI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS01605
gene id: 1654388:EL116_RS01605
uniprot id: A0A2K4AJR2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS08525
gene id: 1654388:EL116_RS08525
uniprot id: A0A2K4AGN3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS04785
gene id: 1654388:EL116_RS04785
uniprot id: A0A2K4AK95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1654388:EL116 RS01870
gene id: 1654388:EL116_RS01870
uniprot id: A0A2K4AIR6
names: Similarity
messages: Belongs to the staphylococcal/streptococcal toxin family.

1654388:EL116 RS11990
gene id: 1654388:EL116_RS11990
uniprot id: A0A2K4AFU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1654388:EL116 RS01905
gene id: 1654388:EL116_RS01905
uniprot id: A0A2K4AJ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the staphylococcal/streptococcal toxin family.
messages: Secreted

1654388:EL116 RS12085
gene id: 1654388:EL116_RS12085
uniprot id: A0A077UL01
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS08030
gene id: 1654388:EL116_RS08030
uniprot id: A0A2K4AGL1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1654388:EL116 RS08595
gene id: 1654388:EL116_RS08595
uniprot id: A0A077UL47
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1654388:EL116 RS02180
gene id: 1654388:EL116_RS02180
uniprot id: A0A077UKI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1654388:EL116 RS02405
gene id: 1654388:EL116_RS02405
uniprot id: A0A2K4AI35
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS09065
gene id: 1654388:EL116_RS09065
uniprot id: A0A2K4AF91
names: Similarity
messages: In the N-terminal section; belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1654388:EL116 RS05615
gene id: 1654388:EL116_RS05615
uniprot id: A0A2K4ADG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1654388:EL116 RS05720
gene id: 1654388:EL116_RS05720
uniprot id: A0A2K4ADI7
names: Similarity
messages: Belongs to the aerolysin family.

1654388:EL116 RS11585
gene id: 1654388:EL116_RS11585
uniprot id: A0A2K4AFZ2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS03125
gene id: 1654388:EL116_RS03125
uniprot id: A0A2K4AEA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS10335
gene id: 1654388:EL116_RS10335
uniprot id: A0A2K4AEY6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1654388:EL116 RS06965
gene id: 1654388:EL116_RS06965
uniprot id: A0A2K4AHX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1654388:EL116 RS03360
gene id: 1654388:EL116_RS03360
uniprot id: A0A2K4AKH4
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS13575
gene id: 1654388:EL116_RS13575
uniprot id: A0A2K4ANX8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1654388:EL116 RS00575
gene id: 1654388:EL116_RS00575
uniprot id: A0A2K4ANC0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1654388:EL116 RS09730
gene id: 1654388:EL116_RS09730
uniprot id: A0A2K4AJH3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS10290
gene id: 1654388:EL116_RS10290
uniprot id: A0A2K4AEU3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

1654388:EL116 RS09965
gene id: 1654388:EL116_RS09965
uniprot id: A0A2K4AJ77
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1654388:EL116 RS00780
gene id: 1654388:EL116_RS00780
uniprot id: A0A2K4AMN5
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS12800
gene id: 1654388:EL116_RS12800
uniprot id: A0A2K4ALN2
names: Similarity
messages: Belongs to the TPP enzyme family.

1654388:EL116 RS03730
gene id: 1654388:EL116_RS03730
uniprot id: A0A2K4AKY7
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1654388:EL116 RS11785
gene id: 1654388:EL116_RS11785
uniprot id: A0A2K4AFU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1654388:EL116 RS01185
gene id: 1654388:EL116_RS01185
uniprot id: A0A2K4AIB7
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS02545
gene id: 1654388:EL116_RS02545
uniprot id: A0A2K4AEL2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1654388:EL116 RS12655
gene id: 1654388:EL116_RS12655
uniprot id: A0A2K4AGY3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1654388:EL116 RS11135
gene id: 1654388:EL116_RS11135
uniprot id: A0A2K4ALX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1654388:EL116 RS02210
gene id: 1654388:EL116_RS02210
uniprot id: A0A2K4AI60
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1654388:EL116 RS10860
gene id: 1654388:EL116_RS10860
uniprot id: A0A2K4AKN4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS06355
gene id: 1654388:EL116_RS06355
uniprot id: A0A2K4AE79
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1654388:EL116 RS00655
gene id: 1654388:EL116_RS00655
uniprot id: A0A2K4AMG8
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS00940
gene id: 1654388:EL116_RS00940
uniprot id: A0A2K4AJZ8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS09395
gene id: 1654388:EL116_RS09395
uniprot id: A0A2K4AF47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1654388:EL116 RS02800
gene id: 1654388:EL116_RS02800
uniprot id: A0A2K4AEG8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS01050
gene id: 1654388:EL116_RS01050
uniprot id: A0A2K4AHD0
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Catalyzes the NADPH dependent reduction of D-ribulose 5-phosphate to D-ribitol 5-phosphate.

1654388:EL116 RS06345
gene id: 1654388:EL116_RS06345
uniprot id: A0A2K4ADX6
names: Similarity
messages: Belongs to the CinA family.

1654388:EL116 RS04395
gene id: 1654388:EL116_RS04395
uniprot id: A0A2K4AJD9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1654388:EL116 RS05735
gene id: 1654388:EL116_RS05735
uniprot id: A0A2K4AED3
names: Similarity
messages: Belongs to the staphylococcal/streptococcal toxin family.

1654388:EL116 RS13455
gene id: 1654388:EL116_RS13455
uniprot id: A0A2K4AMA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpsC/CapA family.
messages: Membrane

1654388:EL116 RS07380
gene id: 1654388:EL116_RS07380
uniprot id: A0A2K4AHQ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS07135
gene id: 1654388:EL116_RS07135
uniprot id: A0A2K4AHM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1654388:EL116 RS06880
gene id: 1654388:EL116_RS06880
uniprot id: A0A077UJQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1654388:EL116 RS01940
gene id: 1654388:EL116_RS01940
uniprot id: A0A2K4AJW4
names: Similarity
messages: Belongs to the staphylococcal tandem lipoprotein family.

1654388:EL116 RS04840
gene id: 1654388:EL116_RS04840
uniprot id: A0A2K4AK83
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1654388:EL116 RS09055
gene id: 1654388:EL116_RS09055
uniprot id: A0A2K4AF84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1654388:EL116 RS02840
gene id: 1654388:EL116_RS02840
uniprot id: A0A077V1R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1654388:EL116 RS07675
gene id: 1654388:EL116_RS07675
uniprot id: A0A2K4AG76
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1654388:EL116 RS11205
gene id: 1654388:EL116_RS11205
uniprot id: A0A2K4AM43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1654388:EL116 RS11630
gene id: 1654388:EL116_RS11630
uniprot id: A0A2K4AGU3
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS13520
gene id: 1654388:EL116_RS13520
uniprot id: A0A2K4ANW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1654388:EL116 RS03535
gene id: 1654388:EL116_RS03535
uniprot id: A0A2K4AJU5
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS02850
gene id: 1654388:EL116_RS02850
uniprot id: A0A2K4AEF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1654388:EL116 RS10765
gene id: 1654388:EL116_RS10765
uniprot id: A0A2K4AEY1
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

1654388:EL116 RS02505
gene id: 1654388:EL116_RS02505
uniprot id: A0A2K4AEL3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1654388:EL116 RS08070
gene id: 1654388:EL116_RS08070
uniprot id: A0A2K4AGJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS05450
gene id: 1654388:EL116_RS05450
uniprot id: A0A2K4AL72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1654388:EL116 RS06195
gene id: 1654388:EL116_RS06195
uniprot id: A0A077UDU1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1654388:EL116 RS12355
gene id: 1654388:EL116_RS12355
uniprot id: A0A2K4AFL7
names: Similarity
messages: Belongs to the YoeB family.

1654388:EL116 RS10150
gene id: 1654388:EL116_RS10150
uniprot id: A0A2K4AJ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1654388:EL116 RS13630
gene id: 1654388:EL116_RS13630
uniprot id: A0A2K4ANY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. HrtA family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

1654388:EL116 RS10720
gene id: 1654388:EL116_RS10720
uniprot id: A0A2K4AEW9
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS02890
gene id: 1654388:EL116_RS02890
uniprot id: A0A2K4AEE5
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

1654388:EL116 RS07450
gene id: 1654388:EL116_RS07450
uniprot id: A0A2K4AHH4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS13850
gene id: 1654388:EL116_RS13850
uniprot id: A0A2K4AHZ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS04650
gene id: 1654388:EL116_RS04650
uniprot id: A0A2K4AKB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: May form a heterooligomeric complex that consists of seven subunits: mnhA1, mnhB1, mnhC1, mnhD1, mnhE1, mnhF1 and mnhG1.
messages: Membrane

1654388:EL116 RS11655
gene id: 1654388:EL116_RS11655
uniprot id: A0A2K4AG43
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS06270
gene id: 1654388:EL116_RS06270
uniprot id: A0A2K4ADS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1654388:EL116 RS07490
gene id: 1654388:EL116_RS07490
uniprot id: A0A2K4AHZ7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

1654388:EL116 RS06175
gene id: 1654388:EL116_RS06175
uniprot id: A0A2K4ADR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1654388:EL116 RS04790
gene id: 1654388:EL116_RS04790
uniprot id: A0A2K4AK91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1654388:EL116 RS08390
gene id: 1654388:EL116_RS08390
uniprot id: A0A2K4AGW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
messages: Probably involved in cell-wall metabolism.
messages: Secreted

1654388:EL116 RS08670
gene id: 1654388:EL116_RS08670
uniprot id: A0A2K4AGX8
names: Similarity
messages: Belongs to the citrate synthase family.

1654388:EL116 RS04935
gene id: 1654388:EL116_RS04935
uniprot id: A0A2K4AK61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1654388:EL116 RS07230
gene id: 1654388:EL116_RS07230
uniprot id: A0A2K4AHL3
names: Similarity
messages: Belongs to the TelA family.

1654388:EL116 RS13675
gene id: 1654388:EL116_RS13675
uniprot id: A0A2K4APU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1654388:EL116 RS11125
gene id: 1654388:EL116_RS11125
uniprot id: W8TUE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1654388:EL116 RS06000
gene id: 1654388:EL116_RS06000
uniprot id: A0A2K4ADN8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. Confers resistance to some classes of antibiotics.

1654388:EL116 RS07460
gene id: 1654388:EL116_RS07460
uniprot id: A0A2K4AI07
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS08380
gene id: 1654388:EL116_RS08380
uniprot id: A0A2K4AGP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS07835
gene id: 1654388:EL116_RS07835
uniprot id: A0A2K4AGB6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.
messages: Membrane
messages: The active site is a redox-active disulfide bond.

1654388:EL116 RS05780
gene id: 1654388:EL116_RS05780
uniprot id: A0A2K4ADI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the staphylococcal hemolytic protein family.
messages: Secreted

1654388:EL116 RS07365
gene id: 1654388:EL116_RS07365
uniprot id: A0A2K4AHM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1654388:EL116 RS03810
gene id: 1654388:EL116_RS03810
uniprot id: A0A2K4AJZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1654388:EL116 RS05275
gene id: 1654388:EL116_RS05275
uniprot id: A0A2K4AM08
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1654388:EL116 RS08800
gene id: 1654388:EL116_RS08800
uniprot id: A0A2K4AFD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1654388:EL116 RS08455
gene id: 1654388:EL116_RS08455
uniprot id: A0A077ULC5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1654388:EL116 RS01920
gene id: 1654388:EL116_RS01920
uniprot id: A0A2K4AIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the staphylococcal/streptococcal toxin family.
messages: Secreted

1654388:EL116 RS05340
gene id: 1654388:EL116_RS05340
uniprot id: A0A2K4ALB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1654388:EL116 RS02520
gene id: 1654388:EL116_RS02520
uniprot id: A0A2K4AEV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1654388:EL116 RS01135
gene id: 1654388:EL116_RS01135
uniprot id: A0A2K4AIC7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1654388:EL116 RS09665
gene id: 1654388:EL116_RS09665
uniprot id: A0A2K4AJH7
names: Similarity
messages: Belongs to the UPF0421 family.

1654388:EL116 RS00355
gene id: 1654388:EL116_RS00355
uniprot id: A0A2K4AMU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1654388:EL116 RS13025
gene id: 1654388:EL116_RS13025
uniprot id: A0A2K4AH48
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1654388:EL116 RS03120
gene id: 1654388:EL116_RS03120
uniprot id: A0A2K4AF60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS12380
gene id: 1654388:EL116_RS12380
uniprot id: A0A2K4AFI8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS02290
gene id: 1654388:EL116_RS02290
uniprot id: A0A2K4AI12
names: Similarity
messages: Belongs to the RutC family.

1654388:EL116 RS03940
gene id: 1654388:EL116_RS03940
uniprot id: A0A2K4ANU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
messages: Cytoplasm

1654388:EL116 RS13080
gene id: 1654388:EL116_RS13080
uniprot id: A0A2K4AH53
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS11455
gene id: 1654388:EL116_RS11455
uniprot id: A0A2K4ALX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1654388:EL116 RS03840
gene id: 1654388:EL116_RS03840
uniprot id: A0A2K4AK03
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1654388:EL116 RS08510
gene id: 1654388:EL116_RS08510
uniprot id: A0A2K4AGN6
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1654388:EL116 RS03915
gene id: 1654388:EL116_RS03915
uniprot id: A0A2K4ANU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1654388:EL116 RS07090
gene id: 1654388:EL116_RS07090
uniprot id: A0A2K4AHP7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS02090
gene id: 1654388:EL116_RS02090
uniprot id: A0A2K4AJ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS09925
gene id: 1654388:EL116_RS09925
uniprot id: A0A2K4AJB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1654388:EL116 RS05430
gene id: 1654388:EL116_RS05430
uniprot id: A0A2K4AL35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1654388:EL116 RS05695
gene id: 1654388:EL116_RS05695
uniprot id: A0A2K4ADV9
names: Subcellular Location Annotation
messages: Secreted

1654388:EL116 RS05180
gene id: 1654388:EL116_RS05180
uniprot id: A0A2K4AKY1
names: Similarity
messages: Belongs to the UPF0039 (ElaA) family.

1654388:EL116 RS03725
gene id: 1654388:EL116_RS03725
uniprot id: A0A2K4AK15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1654388:EL116 RS02175
gene id: 1654388:EL116_RS02175
uniprot id: A0A2K4AJ05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1654388:EL116 RS08625
gene id: 1654388:EL116_RS08625
uniprot id: A0A2K4AGR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1654388:EL116 RS07630
gene id: 1654388:EL116_RS07630
uniprot id: A0A2K4AHK8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS08210
gene id: 1654388:EL116_RS08210
uniprot id: A0A2K4AGI9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1654388:EL116 RS03300
gene id: 1654388:EL116_RS03300
uniprot id: A0A2K4AKR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. HrtA family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

1654388:EL116 RS10325
gene id: 1654388:EL116_RS10325
uniprot id: A0A2K4AER0
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1654388:EL116 RS06015
gene id: 1654388:EL116_RS06015
uniprot id: A0A2K4ADN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1654388:EL116 RS12215
gene id: 1654388:EL116_RS12215
uniprot id: A0A2K4AFL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS04995
gene id: 1654388:EL116_RS04995
uniprot id: A0A2K4AKZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1654388:EL116 RS01880
gene id: 1654388:EL116_RS01880
uniprot id: A0A2K4AIX6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS02380
gene id: 1654388:EL116_RS02380
uniprot id: A0A2K4AJ32
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1654388:EL116 RS02305
gene id: 1654388:EL116_RS02305
uniprot id: A0A0K7NB37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1654388:EL116 RS00550
gene id: 1654388:EL116_RS00550
uniprot id: A0A2K4ALG3
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1654388:EL116 RS12370
gene id: 1654388:EL116_RS12370
uniprot id: A0A2K4AFJ2
names: Similarity
messages: Belongs to the glutamate synthase family.

1654388:EL116 RS05175
gene id: 1654388:EL116_RS05175
uniprot id: A0A2K4ALY0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
messages: Oligomer; forms a ring structure at the cell surface which is important for efficient partitioning of daughter cells after cell division.
messages: Secreted

1654388:EL116 RS01645
gene id: 1654388:EL116_RS01645
uniprot id: A0A077UVN2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1654388:EL116 RS11895
gene id: 1654388:EL116_RS11895
uniprot id: A0A2K4AFS2
names: Similarity
messages: Belongs to the MQO family.

1654388:EL116 RS00695
gene id: 1654388:EL116_RS00695
uniprot id: A0A2K4AMC6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1654388:EL116 RS05750
gene id: 1654388:EL116_RS05750
uniprot id: A0A2K4ADN3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carbamate kinase family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS13290
gene id: 1654388:EL116_RS13290
uniprot id: A0A2K4AHA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

1654388:EL116 RS00245
gene id: 1654388:EL116_RS00245
uniprot id: A0A2K4AMU6
names: Similarity
messages: Belongs to the staphylococcal tandem lipoprotein family.

1654388:EL116 RS00525
gene id: 1654388:EL116_RS00525
uniprot id: A0A2K4ALI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS13545
gene id: 1654388:EL116_RS13545
uniprot id: A0A2K4ANX4
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS09860
gene id: 1654388:EL116_RS09860
uniprot id: A0A2K4AJ95
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1654388:EL116 RS01495
gene id: 1654388:EL116_RS01495
uniprot id: A0A2K4AIK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1654388:EL116 RS08860
gene id: 1654388:EL116_RS08860
uniprot id: A0A2K4AFE2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1654388:EL116 RS03890
gene id: 1654388:EL116_RS03890
uniprot id: A0A2K4AK44
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1654388:EL116 RS08900
gene id: 1654388:EL116_RS08900
uniprot id: A0A2K4AFB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1654388:EL116 RS13445
gene id: 1654388:EL116_RS13445
uniprot id: A0A2K4ALC2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1654388:EL116 RS06420
gene id: 1654388:EL116_RS06420
uniprot id: A0A2K4ADW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1654388:EL116 RS09880
gene id: 1654388:EL116_RS09880
uniprot id: A0A2K4AJA7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1654388:EL116 RS02735
gene id: 1654388:EL116_RS02735
uniprot id: A0A2K4AEJ2
names: Similarity
names: Subunit
messages: Belongs to the azoreductase type 2 family.
messages: Homotetramer.

1654388:EL116 RS03630
gene id: 1654388:EL116_RS03630
uniprot id: A0A2K4AKW6
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1654388:EL116 RS11725
gene id: 1654388:EL116_RS11725
uniprot id: A0A2K4AFZ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1654388:EL116 RS05535
gene id: 1654388:EL116_RS05535
uniprot id: A0A2K4AL63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS13360
gene id: 1654388:EL116_RS13360
uniprot id: A0A2K4AHC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GtfB family.
messages: Cell membrane
messages: Forms a heterotetramer with 2 subunits each of GtfA and GtfB. Part of the accessory SecA2/SecY2 protein translocation apparatus.
messages: Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.

1654388:EL116 RS00720
gene id: 1654388:EL116_RS00720
uniprot id: A0A2K4ANK7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS05480
gene id: 1654388:EL116_RS05480
uniprot id: A0A2K4AL40
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1654388:EL116 RS05325
gene id: 1654388:EL116_RS05325
uniprot id: A0A2K4AM15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1654388:EL116 RS00510
gene id: 1654388:EL116_RS00510
uniprot id: A0A2K4ALN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS02300
gene id: 1654388:EL116_RS02300
uniprot id: A0A2K4AIF0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS01875
gene id: 1654388:EL116_RS01875
uniprot id: A0A2K4AIU6
names: Similarity
messages: Belongs to the staphylococcal/streptococcal toxin family.

1654388:EL116 RS02330
gene id: 1654388:EL116_RS02330
uniprot id: A0A2K4AJ37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1654388:EL116 RS00140
gene id: 1654388:EL116_RS00140
uniprot id: A0A2K4AMS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1654388:EL116 RS11415
gene id: 1654388:EL116_RS11415
uniprot id: A0A2K4ALT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1654388:EL116 RS10450
gene id: 1654388:EL116_RS10450
uniprot id: A0A2K4AEX5
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1654388:EL116 RS00505
gene id: 1654388:EL116_RS00505
uniprot id: A0A2K4ALG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1654388:EL116 RS03850
gene id: 1654388:EL116_RS03850
uniprot id: A0A2K4AK98
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS11375
gene id: 1654388:EL116_RS11375
uniprot id: A0A2K4AMS0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS02410
gene id: 1654388:EL116_RS02410
uniprot id: A0A077UTV6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS10245
gene id: 1654388:EL116_RS10245
uniprot id: A0A2K4AK48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1654388:EL116 RS13555
gene id: 1654388:EL116_RS13555
uniprot id: A0A2K4ANY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0397 family.
messages: Cell membrane

1654388:EL116 RS12095
gene id: 1654388:EL116_RS12095
uniprot id: A0A2K4AFR9
names: Similarity
messages: Belongs to the AHA1 family.

1654388:EL116 RS12185
gene id: 1654388:EL116_RS12185
uniprot id: A0A2K4AFU3
names: Similarity
messages: Belongs to the aerolysin family.

1654388:EL116 RS02655
gene id: 1654388:EL116_RS02655
uniprot id: W8U1C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1654388:EL116 RS07885
gene id: 1654388:EL116_RS07885
uniprot id: A0A2K4AGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1654388:EL116 RS02880
gene id: 1654388:EL116_RS02880
uniprot id: A0A2K4AEG3
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1654388:EL116 RS11060
gene id: 1654388:EL116_RS11060
uniprot id: A0A2K4AJL2
names: Similarity
messages: Belongs to the staphylococcal/streptococcal toxin family.

1654388:EL116 RS11710
gene id: 1654388:EL116_RS11710
uniprot id: A0A2K4AG33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS09030
gene id: 1654388:EL116_RS09030
uniprot id: A0A2K4AFJ7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1654388:EL116 RS07010
gene id: 1654388:EL116_RS07010
uniprot id: A0A2K4AHR6
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1654388:EL116 RS08310
gene id: 1654388:EL116_RS08310
uniprot id: A0A2K4AGK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1654388:EL116 RS03765
gene id: 1654388:EL116_RS03765
uniprot id: A0A2K4AJZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1654388:EL116 RS05455
gene id: 1654388:EL116_RS05455
uniprot id: A0A2K4AL44
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS12340
gene id: 1654388:EL116_RS12340
uniprot id: A0A2K4AG16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1654388:EL116 RS08040
gene id: 1654388:EL116_RS08040
uniprot id: A0A2K4AGF7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1654388:EL116 RS03235
gene id: 1654388:EL116_RS03235
uniprot id: A0A2K4AEA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1654388:EL116 RS11675
gene id: 1654388:EL116_RS11675
uniprot id: A0A2K4AG01
names: Similarity
messages: Belongs to the AHA1 family.

1654388:EL116 RS09710
gene id: 1654388:EL116_RS09710
uniprot id: A0A2K4AKE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1654388:EL116 RS11300
gene id: 1654388:EL116_RS11300
uniprot id: A0A2K4AM05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS07875
gene id: 1654388:EL116_RS07875
uniprot id: A0A2K4AGI1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1654388:EL116 RS12680
gene id: 1654388:EL116_RS12680
uniprot id: A0A2K4ALK9
names: Similarity
messages: Belongs to the FBPase class 3 family.

1654388:EL116 RS03920
gene id: 1654388:EL116_RS03920
uniprot id: A0A2K4ANU2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1654388:EL116 RS00895
gene id: 1654388:EL116_RS00895
uniprot id: A0A2K4AMN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS11615
gene id: 1654388:EL116_RS11615
uniprot id: A0A2K4AG93
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS00825
gene id: 1654388:EL116_RS00825
uniprot id: A0A2K4AMM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS13475
gene id: 1654388:EL116_RS13475
uniprot id: A0A2K4ALI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: cell wall

1654388:EL116 RS07810
gene id: 1654388:EL116_RS07810
uniprot id: A0A2K4AGE3
names: Similarity
messages: Belongs to the UPF0421 family.

1654388:EL116 RS00635
gene id: 1654388:EL116_RS00635
uniprot id: A0A2K4AMH0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1654388:EL116 RS11130
gene id: 1654388:EL116_RS11130
uniprot id: A0A2K4AM01
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS12925
gene id: 1654388:EL116_RS12925
uniprot id: A0A2K4AI40
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family. CrtM subfamily.
messages: Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress. Catalyzes the head-to-head condensation of two molecules of farnesyl diphosphate (FPP) into the colorless C(30) carotenoid 4,4'-diapophytoene (dehydrosqualene).

1654388:EL116 RS05150
gene id: 1654388:EL116_RS05150
uniprot id: A0A2K4AL08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C47 family.
messages: Secreted

1654388:EL116 RS10300
gene id: 1654388:EL116_RS10300
uniprot id: A0A2K4AEP7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1654388:EL116 RS05610
gene id: 1654388:EL116_RS05610
uniprot id: A0A2K4ADF8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1654388:EL116 RS09025
gene id: 1654388:EL116_RS09025
uniprot id: A0A2K4AFR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1654388:EL116 RS11600
gene id: 1654388:EL116_RS11600
uniprot id: A0A077UH28
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1654388:EL116 RS10310
gene id: 1654388:EL116_RS10310
uniprot id: A0A2K4AEN7
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B.

1654388:EL116 RS05380
gene id: 1654388:EL116_RS05380
uniprot id: A0A2K4AL18
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1654388:EL116 RS10440
gene id: 1654388:EL116_RS10440
uniprot id: A0A2K4AF05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1654388:EL116 RS08845
gene id: 1654388:EL116_RS08845
uniprot id: A0A2K4AG94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS09360
gene id: 1654388:EL116_RS09360
uniprot id: A0A2K4AFB4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS03060
gene id: 1654388:EL116_RS03060
uniprot id: A0A2K4AEF5
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

1654388:EL116 RS02025
gene id: 1654388:EL116_RS02025
uniprot id: A0A2K4AJ15
names: Caution
names: Similarity
messages: Belongs to the phenol-soluble modulin alpha peptides family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS13180
gene id: 1654388:EL116_RS13180
uniprot id: A0A2K4AH77
names: Similarity
messages: Belongs to the GbsR family.

1654388:EL116 RS02780
gene id: 1654388:EL116_RS02780
uniprot id: A0A2K4AFC6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS08145
gene id: 1654388:EL116_RS08145
uniprot id: A0A2K4AGN0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1654388:EL116 RS10060
gene id: 1654388:EL116_RS10060
uniprot id: A0A2K4AJ57
names: Similarity
messages: Belongs to the aerolysin family.

1654388:EL116 RS06095
gene id: 1654388:EL116_RS06095
uniprot id: A0A2K4ADR6
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1654388:EL116 RS01485
gene id: 1654388:EL116_RS01485
uniprot id: A0A2K4AIQ5
names: Function
names: Subunit
messages: Homodimer or homotrimer. Seems to be a monomer when not phosphorylated.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1654388:EL116 RS01775
gene id: 1654388:EL116_RS01775
uniprot id: A0A2K4AIV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1654388:EL116 RS06100
gene id: 1654388:EL116_RS06100
uniprot id: A0A2K4ADQ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1654388:EL116 RS09130
gene id: 1654388:EL116_RS09130
uniprot id: A0A2K4AF73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

1654388:EL116 RS02370
gene id: 1654388:EL116_RS02370
uniprot id: A0A2K4AI31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1654388:EL116 RS06960
gene id: 1654388:EL116_RS06960
uniprot id: A0A2K4AIV7
names: Similarity
messages: Belongs to the HesB/IscA family.

1654388:EL116 RS07990
gene id: 1654388:EL116_RS07990
uniprot id: A0A2K4AGE6
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS00040
gene id: 1654388:EL116_RS00040
uniprot id: A0A2K4AP14
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1654388:EL116 RS02235
gene id: 1654388:EL116_RS02235
uniprot id: A0A2K4AI01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

1654388:EL116 RS05605
gene id: 1654388:EL116_RS05605
uniprot id: A0A2K4ADF4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1654388:EL116 RS01225
gene id: 1654388:EL116_RS01225
uniprot id: A0A2K4AI43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EssC family.
messages: Membrane

1654388:EL116 RS11320
gene id: 1654388:EL116_RS11320
uniprot id: A0A2K4AMT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS03110
gene id: 1654388:EL116_RS03110
uniprot id: A0A2K4AEE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS12055
gene id: 1654388:EL116_RS12055
uniprot id: A0A2K4AFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS00995
gene id: 1654388:EL116_RS00995
uniprot id: A0A2K4AHE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS08340
gene id: 1654388:EL116_RS08340
uniprot id: A0A2K4AH07
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1654388:EL116 RS08700
gene id: 1654388:EL116_RS08700
uniprot id: A0A2K4AGV2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1654388:EL116 RS08385
gene id: 1654388:EL116_RS08385
uniprot id: A0A2K4AGQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS07815
gene id: 1654388:EL116_RS07815
uniprot id: A0A2K4AGK7
names: Caution
names: Similarity
messages: Belongs to the UPF0403 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS01445
gene id: 1654388:EL116_RS01445
uniprot id: A0A2K4AIJ4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1654388:EL116 RS02690
gene id: 1654388:EL116_RS02690
uniprot id: A0A2K4AEI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family. HchA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE). Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA. Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair. Plays an important role in protecting cells from carbonyl stress.

1654388:EL116 RS10360
gene id: 1654388:EL116_RS10360
uniprot id: A0A2K4AEP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1654388:EL116 RS07695
gene id: 1654388:EL116_RS07695
uniprot id: A0A2K4AH47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1654388:EL116 RS12110
gene id: 1654388:EL116_RS12110
uniprot id: A0A2K4AFP1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1654388:EL116 RS07055
gene id: 1654388:EL116_RS07055
uniprot id: A0A2K4AHT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1654388:EL116 RS01470
gene id: 1654388:EL116_RS01470
uniprot id: A0A2K4AIJ8
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS00930
gene id: 1654388:EL116_RS00930
uniprot id: A0A2K4AMR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCIN family.
messages: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses.
messages: Secreted

1654388:EL116 RS10570
gene id: 1654388:EL116_RS10570
uniprot id: A0A2K4AET6
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1654388:EL116 RS06985
gene id: 1654388:EL116_RS06985
uniprot id: A0A2K4AHR9
names: Similarity
messages: Belongs to the transcriptional antiterminator BglG family. GlcT subfamily.

1654388:EL116 RS13140
gene id: 1654388:EL116_RS13140
uniprot id: A0A2K4AH79
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1654388:EL116 RS08600
gene id: 1654388:EL116_RS08600
uniprot id: A0A2K4AGT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS07555
gene id: 1654388:EL116_RS07555
uniprot id: A0A2K4AHM0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1654388:EL116 RS10190
gene id: 1654388:EL116_RS10190
uniprot id: A0A2K4AJ59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1654388:EL116 RS04645
gene id: 1654388:EL116_RS04645
uniprot id: A0A2K4AKC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS09790
gene id: 1654388:EL116_RS09790
uniprot id: A0A2K4AJD7
names: Similarity
messages: Belongs to the UPF0421 family.

1654388:EL116 RS06090
gene id: 1654388:EL116_RS06090
uniprot id: A0A077UDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1654388:EL116 RS13585
gene id: 1654388:EL116_RS13585
uniprot id: A0A2K4AP24
names: Subcellular Location Annotation
messages: Cell membrane

1654388:EL116 RS00015
gene id: 1654388:EL116_RS00015
uniprot id: A0A2K4AP05
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS05665
gene id: 1654388:EL116_RS05665
uniprot id: A0A2K4ADH3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1654388:EL116 RS09850
gene id: 1654388:EL116_RS09850
uniprot id: A0A2K4AJI7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1654388:EL116 RS06515
gene id: 1654388:EL116_RS06515
uniprot id: A0A2K4AE03
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS04400
gene id: 1654388:EL116_RS04400
uniprot id: A0A2K4AIE9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS13330
gene id: 1654388:EL116_RS13330
uniprot id: A0A2K4AHF7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer or homotrimer. Seems to be a monomer when not phosphorylated.
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1654388:EL116 RS07175
gene id: 1654388:EL116_RS07175
uniprot id: A0A2K4AHT5
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1654388:EL116 RS05670
gene id: 1654388:EL116_RS05670
uniprot id: A0A2K4ADG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1654388:EL116 RS09920
gene id: 1654388:EL116_RS09920
uniprot id: A0A2K4AKA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS04720
gene id: 1654388:EL116_RS04720
uniprot id: A0A2K4AKF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS08765
gene id: 1654388:EL116_RS08765
uniprot id: A0A2K4AGW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS13605
gene id: 1654388:EL116_RS13605
uniprot id: A0A2K4ANX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1654388:EL116 RS08280
gene id: 1654388:EL116_RS08280
uniprot id: A0A2K4AGN2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1654388:EL116 RS09770
gene id: 1654388:EL116_RS09770
uniprot id: A0A077VLC3
names: Subcellular Location Annotation
messages: Cell membrane

1654388:EL116 RS03495
gene id: 1654388:EL116_RS03495
uniprot id: A0A2K4AK30
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1654388:EL116 RS12240
gene id: 1654388:EL116_RS12240
uniprot id: A0A2K4AG34
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1654388:EL116 RS03855
gene id: 1654388:EL116_RS03855
uniprot id: A0A2K4AK13
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS11230
gene id: 1654388:EL116_RS11230
uniprot id: A0A2K4ALX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1654388:EL116 RS13480
gene id: 1654388:EL116_RS13480
uniprot id: A0A2K4ALE3
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1654388:EL116 RS07890
gene id: 1654388:EL116_RS07890
uniprot id: A0A2K4AGC7
names: Similarity
messages: Belongs to the peptidase M24B family.

1654388:EL116 RS08365
gene id: 1654388:EL116_RS08365
uniprot id: A0A2K4AGK2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1654388:EL116 RS10630
gene id: 1654388:EL116_RS10630
uniprot id: W8UVX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1654388:EL116 RS11445
gene id: 1654388:EL116_RS11445
uniprot id: A0A2K4ALT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS10430
gene id: 1654388:EL116_RS10430
uniprot id: A0A2K4AET3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS02285
gene id: 1654388:EL116_RS02285
uniprot id: A0A2K4AHZ3
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1654388:EL116 RS12760
gene id: 1654388:EL116_RS12760
uniprot id: A0A2K4ALQ3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1654388:EL116 RS03445
gene id: 1654388:EL116_RS03445
uniprot id: A0A2K4AKK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1654388:EL116 RS02385
gene id: 1654388:EL116_RS02385
uniprot id: A0A2K4AI47
names: Similarity
names: Subunit
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.
messages: Homodimer.

1654388:EL116 RS08095
gene id: 1654388:EL116_RS08095
uniprot id: A0A2K4AGF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1654388:EL116 RS10580
gene id: 1654388:EL116_RS10580
uniprot id: A0A2K4AFP9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1654388:EL116 RS03750
gene id: 1654388:EL116_RS03750
uniprot id: A0A2K4AK81
names: Function
messages: May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

1654388:EL116 RS00850
gene id: 1654388:EL116_RS00850
uniprot id: A0A2K4AMN3
names: Similarity
messages: Belongs to the peptidase M23B family.

1654388:EL116 RS09270
gene id: 1654388:EL116_RS09270
uniprot id: A0A2K4AFM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the staphylococcal/streptococcal toxin family.
messages: Secreted

1654388:EL116 RS13230
gene id: 1654388:EL116_RS13230
uniprot id: A0A2K4AH88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. HrtB subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

1654388:EL116 RS10515
gene id: 1654388:EL116_RS10515
uniprot id: A0A2K4AES6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1654388:EL116 RS11180
gene id: 1654388:EL116_RS11180
uniprot id: A0A2K4ALY6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1654388:EL116 RS08465
gene id: 1654388:EL116_RS08465
uniprot id: A0A2K4AGP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1654388:EL116 RS02615
gene id: 1654388:EL116_RS02615
uniprot id: A0A077UNE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1654388:EL116 RS04465
gene id: 1654388:EL116_RS04465
uniprot id: A0A077V1G8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1654388:EL116 RS02600
gene id: 1654388:EL116_RS02600
uniprot id: W8U1D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1654388:EL116 RS10610
gene id: 1654388:EL116_RS10610
uniprot id: A0A2K4AF06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS08475
gene id: 1654388:EL116_RS08475
uniprot id: A0A2K4AHM8
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1654388:EL116 RS01670
gene id: 1654388:EL116_RS01670
uniprot id: A0A077UZF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1654388:EL116 RS07005
gene id: 1654388:EL116_RS07005
uniprot id: A0A2K4AHU0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1654388:EL116 RS02725
gene id: 1654388:EL116_RS02725
uniprot id: A0A2K4AEI4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1654388:EL116 RS09885
gene id: 1654388:EL116_RS09885
uniprot id: A0A2K4AJ87
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

1654388:EL116 RS08345
gene id: 1654388:EL116_RS08345
uniprot id: A0A2K4AGR6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1654388:EL116 RS11185
gene id: 1654388:EL116_RS11185
uniprot id: A0A2K4ALW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1654388:EL116 RS05160
gene id: 1654388:EL116_RS05160
uniprot id: A0A2K4AKY4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1654388:EL116 RS05685
gene id: 1654388:EL116_RS05685
uniprot id: A0A2K4ADL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHIPS/FLIPr family.
messages: Secreted

1654388:EL116 RS07925
gene id: 1654388:EL116_RS07925
uniprot id: A0A2K4AGJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1654388:EL116 RS11290
gene id: 1654388:EL116_RS11290
uniprot id: A0A0H2K0A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1654388:EL116 RS05560
gene id: 1654388:EL116_RS05560
uniprot id: A0A2K4AL69
names: Subcellular Location Annotation
messages: cell wall

1654388:EL116 RS11435
gene id: 1654388:EL116_RS11435
uniprot id: A0A2K4ALT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1654388:EL116 RS01710
gene id: 1654388:EL116_RS01710
uniprot id: A0A2K4AIN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1654388:EL116 RS08590
gene id: 1654388:EL116_RS08590
uniprot id: A0A077VMP6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1654388:EL116 RS08630
gene id: 1654388:EL116_RS08630
uniprot id: A0A2K4AGR9
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

1654388:EL116 RS09960
gene id: 1654388:EL116_RS09960
uniprot id: A0A2K4AJ75
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

1654388:EL116 RS09680
gene id: 1654388:EL116_RS09680
uniprot id: A0A077USC5
names: Similarity
messages: Belongs to the UPF0374 family.

1654388:EL116 RS00865
gene id: 1654388:EL116_RS00865
uniprot id: A0A2K4AMQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS11865
gene id: 1654388:EL116_RS11865
uniprot id: A0A2K4AG04
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS03355
gene id: 1654388:EL116_RS03355
uniprot id: A0A2K4AKL2
names: Caution
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS05165
gene id: 1654388:EL116_RS05165
uniprot id: A0A2K4AKY5
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1654388:EL116 RS11150
gene id: 1654388:EL116_RS11150
uniprot id: A0A077UG91
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1654388:EL116 RS08565
gene id: 1654388:EL116_RS08565
uniprot id: A0A2K4AGQ6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1654388:EL116 RS09225
gene id: 1654388:EL116_RS09225
uniprot id: A0A2K4AF96
names: Similarity
messages: Belongs to the peptidase S8 family.

1654388:EL116 RS08875
gene id: 1654388:EL116_RS08875
uniprot id: A0A2K4AFU8
names: Function
names: Similarity
messages: Belongs to the histone deacetylase family.
messages: Role in growth on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source.

1654388:EL116 RS05210
gene id: 1654388:EL116_RS05210
uniprot id: A0A2K4AKZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds a copper B center.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Heme A3.
messages: Membrane

1654388:EL116 RS10705
gene id: 1654388:EL116_RS10705
uniprot id: A0A2K4AEW2
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1654388:EL116 RS05235
gene id: 1654388:EL116_RS05235
uniprot id: A0A2K4AKZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1654388:EL116 RS06300
gene id: 1654388:EL116_RS06300
uniprot id: A0A2K4AE73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1654388:EL116 RS08675
gene id: 1654388:EL116_RS08675
uniprot id: A0A2K4AGS3
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS00685
gene id: 1654388:EL116_RS00685
uniprot id: A0A2K4AMG2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS03835
gene id: 1654388:EL116_RS03835
uniprot id: A0A2K4AJZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1654388:EL116 RS01740
gene id: 1654388:EL116_RS01740
uniprot id: A0A2K4AIS7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1654388:EL116 RS06910
gene id: 1654388:EL116_RS06910
uniprot id: A0A2K4AIW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1654388:EL116 RS01100
gene id: 1654388:EL116_RS01100
uniprot id: A0A2K4AJC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CidA/LrgA family. LrgA subfamily.
messages: Cell membrane
messages: Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS00760
gene id: 1654388:EL116_RS00760
uniprot id: A0A2K4AMQ4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1654388:EL116 RS01900
gene id: 1654388:EL116_RS01900
uniprot id: A0A2K4AJ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the staphylococcal/streptococcal toxin family.
messages: Secreted

1654388:EL116 RS05645
gene id: 1654388:EL116_RS05645
uniprot id: A0A2K4ADU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1654388:EL116 RS02740
gene id: 1654388:EL116_RS02740
uniprot id: A0A448CTU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serine-aspartate repeat-containing protein (SDr) family.
messages: cell wall

1654388:EL116 RS12835
gene id: 1654388:EL116_RS12835
uniprot id: A0A2K4ALM8
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1654388:EL116 RS08015
gene id: 1654388:EL116_RS08015
uniprot id: A0A2K4AGI2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

1654388:EL116 RS09935
gene id: 1654388:EL116_RS09935
uniprot id: A0A2K4AJ93
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

1654388:EL116 RS02130
gene id: 1654388:EL116_RS02130
uniprot id: A0A2K4AIX4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1654388:EL116 RS02835
gene id: 1654388:EL116_RS02835
uniprot id: A0A2K4AEF8
names: Similarity
messages: Belongs to the ThiD family.

1654388:EL116 RS07845
gene id: 1654388:EL116_RS07845
uniprot id: A0A077VKY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1654388:EL116 RS10520
gene id: 1654388:EL116_RS10520
uniprot id: A0A077VLK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1654388:EL116 RS08820
gene id: 1654388:EL116_RS08820
uniprot id: A0A2K4AFK5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1654388:EL116 RS11780
gene id: 1654388:EL116_RS11780
uniprot id: A0A2K4AGR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS01660
gene id: 1654388:EL116_RS01660
uniprot id: W8TPC6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1654388:EL116 RS08415
gene id: 1654388:EL116_RS08415
uniprot id: A0A2K4AGN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1654388:EL116 RS06170
gene id: 1654388:EL116_RS06170
uniprot id: A0A2K4AEK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1654388:EL116 RS06055
gene id: 1654388:EL116_RS06055
uniprot id: A0A2K4ADP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1654388:EL116 RS12515
gene id: 1654388:EL116_RS12515
uniprot id: A0A2K4AFS1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1654388:EL116 RS13240
gene id: 1654388:EL116_RS13240
uniprot id: A0A2K4AH99
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS08080
gene id: 1654388:EL116_RS08080
uniprot id: A0A2K4AGQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1654388:EL116 RS12560
gene id: 1654388:EL116_RS12560
uniprot id: A0A077UXQ0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1654388:EL116 RS11485
gene id: 1654388:EL116_RS11485
uniprot id: A0A2K4ALS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1654388:EL116 RS08685
gene id: 1654388:EL116_RS08685
uniprot id: A0A2K4AGT0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS09735
gene id: 1654388:EL116_RS09735
uniprot id: A0A2K4AJC1
names: Caution
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS10920
gene id: 1654388:EL116_RS10920
uniprot id: A0A2K4AJP5
names: Function
names: Similarity
messages: Belongs to the asp23 family.
messages: May play a key role in alkaline pH tolerance.

1654388:EL116 RS11490
gene id: 1654388:EL116_RS11490
uniprot id: A0A2K4ALQ7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1654388:EL116 RS06290
gene id: 1654388:EL116_RS06290
uniprot id: A0A2K4ADW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS11015
gene id: 1654388:EL116_RS11015
uniprot id: A0A2K4AKK4
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

1654388:EL116 RS04680
gene id: 1654388:EL116_RS04680
uniprot id: A0A2K4AKA8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1654388:EL116 RS05910
gene id: 1654388:EL116_RS05910
uniprot id: A0A2K4AEG1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1654388:EL116 RS08335
gene id: 1654388:EL116_RS08335
uniprot id: A0A2K4AGW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1654388:EL116 RS02280
gene id: 1654388:EL116_RS02280
uniprot id: A0A2K4AI56
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1654388:EL116 RS05820
gene id: 1654388:EL116_RS05820
uniprot id: A0A2K4ADX9
names: Similarity
messages: Belongs to the transpeptidase family.

1654388:EL116 RS08695
gene id: 1654388:EL116_RS08695
uniprot id: A0A2K4AHS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1654388:EL116 RS05390
gene id: 1654388:EL116_RS05390
uniprot id: A0A2K4ALB9
names: Similarity
messages: Belongs to the UPF0223 family.

1654388:EL116 RS11145
gene id: 1654388:EL116_RS11145
uniprot id: A0A2K4AM10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS02555
gene id: 1654388:EL116_RS02555
uniprot id: A0A2K4AEK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1654388:EL116 RS06425
gene id: 1654388:EL116_RS06425
uniprot id: A0A2K4ADV1
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1654388:EL116 RS04775
gene id: 1654388:EL116_RS04775
uniprot id: A0A2K4AK97
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1654388:EL116 RS10125
gene id: 1654388:EL116_RS10125
uniprot id: A0A2K4AJ81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AgrB family.
messages: Cell membrane
messages: Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS08155
gene id: 1654388:EL116_RS08155
uniprot id: A0A2K4AGI0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1654388:EL116 RS13115
gene id: 1654388:EL116_RS13115
uniprot id: A0A077W0Q6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS00950
gene id: 1654388:EL116_RS00950
uniprot id: A0A2K4AJP3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1654388:EL116 RS09480
gene id: 1654388:EL116_RS09480
uniprot id: A0A2K4AF51
names: Subcellular Location Annotation
messages: Cell membrane

1654388:EL116 RS01030
gene id: 1654388:EL116_RS01030
uniprot id: A0A2K4AH10
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1654388:EL116 RS00590
gene id: 1654388:EL116_RS00590
uniprot id: A0A2K4AMG7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1654388:EL116 RS03560
gene id: 1654388:EL116_RS03560
uniprot id: A0A2K4AJW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

1654388:EL116 RS05245
gene id: 1654388:EL116_RS05245
uniprot id: A0A2K4AL80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1654388:EL116 RS04950
gene id: 1654388:EL116_RS04950
uniprot id: A0A2K4AKF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1654388:EL116 RS06580
gene id: 1654388:EL116_RS06580
uniprot id: A0A2K4ADZ1
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1654388:EL116 RS05840
gene id: 1654388:EL116_RS05840
uniprot id: A0A2K4ADK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1654388:EL116 RS05000
gene id: 1654388:EL116_RS05000
uniprot id: A0A2K4ALV1
names: Subcellular Location Annotation
messages: Cell membrane

1654388:EL116 RS07275
gene id: 1654388:EL116_RS07275
uniprot id: A0A2K4AIQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1654388:EL116 RS03205
gene id: 1654388:EL116_RS03205
uniprot id: A0A2K4AEH6
names: Function
names: Subcellular Location Annotation
messages: May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation.
messages: Membrane

1654388:EL116 RS11305
gene id: 1654388:EL116_RS11305
uniprot id: A0A2K4AM35
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1654388:EL116 RS05660
gene id: 1654388:EL116_RS05660
uniprot id: A0A2K4ADG8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1654388:EL116 RS07480
gene id: 1654388:EL116_RS07480
uniprot id: A0A2K4AHI0
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

1654388:EL116 RS04670
gene id: 1654388:EL116_RS04670
uniprot id: A0A2K4AKB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: May form a heterooligomeric complex that consists of seven subunits: mnhA1, mnhB1, mnhC1, mnhD1, mnhE1, mnhF1 and mnhG1.
messages: Membrane

1654388:EL116 RS04735
gene id: 1654388:EL116_RS04735
uniprot id: A0A2K4AK99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Essential for cell viability.
messages: Membrane

1654388:EL116 RS08735
gene id: 1654388:EL116_RS08735
uniprot id: A0A2K4AGT7
names: Similarity
messages: Belongs to the peptidase M24B family.

1654388:EL116 RS03150
gene id: 1654388:EL116_RS03150
uniprot id: A0A2K4AEP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS08610
gene id: 1654388:EL116_RS08610
uniprot id: A0A2K4AH54
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS10505
gene id: 1654388:EL116_RS10505
uniprot id: W8TUP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1654388:EL116 RS11440
gene id: 1654388:EL116_RS11440
uniprot id: A0A2K4ALR5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1654388:EL116 RS06765
gene id: 1654388:EL116_RS06765
uniprot id: A0A2K4AHX8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS10460
gene id: 1654388:EL116_RS10460
uniprot id: A0A2K4AES9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

1654388:EL116 RS01040
gene id: 1654388:EL116_RS01040
uniprot id: A0A2K4AGZ9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1654388:EL116 RS11395
gene id: 1654388:EL116_RS11395
uniprot id: A0A2K4ALU4
names: Similarity
messages: Belongs to the MoaD family.

1654388:EL116 RS10160
gene id: 1654388:EL116_RS10160
uniprot id: A0A2K4AJC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS07130
gene id: 1654388:EL116_RS07130
uniprot id: A0A2K4AHN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS09660
gene id: 1654388:EL116_RS09660
uniprot id: A0A2K4AJG0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS03310
gene id: 1654388:EL116_RS03310
uniprot id: W8U126
names: Similarity
messages: Belongs to the UPF0111 family.

1654388:EL116 RS04510
gene id: 1654388:EL116_RS04510
uniprot id: A0A2K4AN45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS11960
gene id: 1654388:EL116_RS11960
uniprot id: A0A2K4AFS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1654388:EL116 RS02860
gene id: 1654388:EL116_RS02860
uniprot id: A0A2K4AEU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1654388:EL116 RS13325
gene id: 1654388:EL116_RS13325
uniprot id: A0A2K4AHP6
names: Function
names: Subunit
messages: Homodimer or homotrimer. Seems to be a monomer when not phosphorylated.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1654388:EL116 RS04710
gene id: 1654388:EL116_RS04710
uniprot id: A0A2K4AKA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1654388:EL116 RS05930
gene id: 1654388:EL116_RS05930
uniprot id: A0A2K4AE01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1654388:EL116 RS08840
gene id: 1654388:EL116_RS08840
uniprot id: A0A2K4AFG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS12565
gene id: 1654388:EL116_RS12565
uniprot id: A0A3S4NW39
names: Subcellular Location Annotation
messages: cell wall

1654388:EL116 RS09785
gene id: 1654388:EL116_RS09785
uniprot id: A0A2K4AJB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1654388:EL116 RS00020
gene id: 1654388:EL116_RS00020
uniprot id: A0A2K4AP03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1654388:EL116 RS09845
gene id: 1654388:EL116_RS09845
uniprot id: A0A2K4AJL9
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1654388:EL116 RS03215
gene id: 1654388:EL116_RS03215
uniprot id: A0A2K4AEA4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS01690
gene id: 1654388:EL116_RS01690
uniprot id: A0A2K4AJ18
names: Similarity
messages: Belongs to the staphylococcal/streptococcal toxin family.

1654388:EL116 RS00795
gene id: 1654388:EL116_RS00795
uniprot id: A0A2K4AMK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1654388:EL116 RS00390
gene id: 1654388:EL116_RS00390
uniprot id: A0A2K4AN05
names: Similarity
messages: Belongs to the IucA/IucC family.

1654388:EL116 RS00560
gene id: 1654388:EL116_RS00560
uniprot id: A0A2K4AMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpsC/CapA family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS10405
gene id: 1654388:EL116_RS10405
uniprot id: A0A2K4AEP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1654388:EL116 RS12270
gene id: 1654388:EL116_RS12270
uniprot id: A0A2K4AFL1
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS10510
gene id: 1654388:EL116_RS10510
uniprot id: A0A2K4AET9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1654388:EL116 RS03645
gene id: 1654388:EL116_RS03645
uniprot id: A0A2K4AK51
names: Similarity
messages: Belongs to the EamA transporter family.

1654388:EL116 RS11595
gene id: 1654388:EL116_RS11595
uniprot id: A0A2K4AFY6
names: Caution
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS05880
gene id: 1654388:EL116_RS05880
uniprot id: A0A2K4ADY7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1654388:EL116 RS05190
gene id: 1654388:EL116_RS05190
uniprot id: A0A2K4AL76
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1654388:EL116 RS06915
gene id: 1654388:EL116_RS06915
uniprot id: A0A2K4AHY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1654388:EL116 RS12130
gene id: 1654388:EL116_RS12130
uniprot id: A0A2K4AFV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1654388:EL116 RS07280
gene id: 1654388:EL116_RS07280
uniprot id: A0A2K4AHR7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS13510
gene id: 1654388:EL116_RS13510
uniprot id: A0A2K4ANY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1654388:EL116 RS01160
gene id: 1654388:EL116_RS01160
uniprot id: A0A2K4AJB2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS12295
gene id: 1654388:EL116_RS12295
uniprot id: A0A2K4AFW4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1654388:EL116 RS02720
gene id: 1654388:EL116_RS02720
uniprot id: A0A2K4AFD9
names: Similarity
messages: Belongs to the DCK/DGK family.

1654388:EL116 RS05105
gene id: 1654388:EL116_RS05105
uniprot id: A0A077UIL0
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS01630
gene id: 1654388:EL116_RS01630
uniprot id: A0A2K4AJ07
names: Similarity
messages: Belongs to the ParB family.

1654388:EL116 RS02610
gene id: 1654388:EL116_RS02610
uniprot id: A0A077W4L0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1654388:EL116 RS10370
gene id: 1654388:EL116_RS10370
uniprot id: A0A2K4AFK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1654388:EL116 RS04725
gene id: 1654388:EL116_RS04725
uniprot id: A0A2K4AKA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS00500
gene id: 1654388:EL116_RS00500
uniprot id: A0A448CSN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1654388:EL116 RS12720
gene id: 1654388:EL116_RS12720
uniprot id: A0A2K4ALJ9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1654388:EL116 RS12985
gene id: 1654388:EL116_RS12985
uniprot id: A0A2K4AH61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1654388:EL116 RS10165
gene id: 1654388:EL116_RS10165
uniprot id: A0A2K4AJ44
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1654388:EL116 RS07585
gene id: 1654388:EL116_RS07585
uniprot id: A0A2K4AHR2
names: Function
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1654388:EL116 RS13465
gene id: 1654388:EL116_RS13465
uniprot id: A0A2K4ALB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane
messages: N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homomer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity.

1654388:EL116 RS09415
gene id: 1654388:EL116_RS09415
uniprot id: A0A2K4AFJ6
names: Similarity
messages: Belongs to the UPF0342 family.

1654388:EL116 RS05925
gene id: 1654388:EL116_RS05925
uniprot id: A0A2K4ADR7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS00465
gene id: 1654388:EL116_RS00465
uniprot id: A0A2K4AFB0
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS08025
gene id: 1654388:EL116_RS08025
uniprot id: A0A2K4AGW4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS06830
gene id: 1654388:EL116_RS06830
uniprot id: A0A3S4NKM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.
messages: Cytoplasm

1654388:EL116 RS04185
gene id: 1654388:EL116_RS04185
uniprot id: A0A2K4ANN5
names: Similarity
messages: Belongs to the peptidase S14 family.

1654388:EL116 RS05350
gene id: 1654388:EL116_RS05350
uniprot id: A0A2K4AL48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1654388:EL116 RS00065
gene id: 1654388:EL116_RS00065
uniprot id: A0A2K4AP07
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

1654388:EL116 RS09145
gene id: 1654388:EL116_RS09145
uniprot id: A0A2K4AFP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1654388:EL116 RS10975
gene id: 1654388:EL116_RS10975
uniprot id: A0A2K4AJN3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1654388:EL116 RS04730
gene id: 1654388:EL116_RS04730
uniprot id: A0A2K4AKA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS05915
gene id: 1654388:EL116_RS05915
uniprot id: A0A2K4ADK4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS13370
gene id: 1654388:EL116_RS13370
uniprot id: A0A3S4S7B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1654388:EL116 RS08810
gene id: 1654388:EL116_RS08810
uniprot id: A0A2K4AFF2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1654388:EL116 RS11470
gene id: 1654388:EL116_RS11470
uniprot id: A0A2K4ALQ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1654388:EL116 RS10660
gene id: 1654388:EL116_RS10660
uniprot id: A0A2K4AF14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1654388:EL116 RS05280
gene id: 1654388:EL116_RS05280
uniprot id: A0A2K4AKZ9
names: Similarity
messages: Belongs to the GARS family.

1654388:EL116 RS01045
gene id: 1654388:EL116_RS01045
uniprot id: A0A2K4AH60
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
messages: Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS04665
gene id: 1654388:EL116_RS04665
uniprot id: A0A2K4AKF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: May form a heterooligomeric complex that consists of seven subunits: mnhA1, mnhB1, mnhC1, mnhD1, mnhE1, mnhF1 and mnhG1.
messages: Membrane
messages: Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.

1654388:EL116 RS03015
gene id: 1654388:EL116_RS03015
uniprot id: A0A2K4AEM0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS02215
gene id: 1654388:EL116_RS02215
uniprot id: A0A2K4AI27
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1654388:EL116 RS10915
gene id: 1654388:EL116_RS10915
uniprot id: A0A2K4AJQ4
names: Similarity
messages: Belongs to the IucA/IucC family.

1654388:EL116 RS11825
gene id: 1654388:EL116_RS11825
uniprot id: A0A2K4AFX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS13100
gene id: 1654388:EL116_RS13100
uniprot id: A0A2K4AI72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1654388:EL116 RS04955
gene id: 1654388:EL116_RS04955
uniprot id: A0A2K4AKD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS04815
gene id: 1654388:EL116_RS04815
uniprot id: A0A2K4AK85
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1654388:EL116 RS09355
gene id: 1654388:EL116_RS09355
uniprot id: A0A2K4AF36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS06020
gene id: 1654388:EL116_RS06020
uniprot id: A0A2K4ADR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1654388:EL116 RS13220
gene id: 1654388:EL116_RS13220
uniprot id: A0A2K4AHM5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1654388:EL116 RS13525
gene id: 1654388:EL116_RS13525
uniprot id: A0A2K4ANU7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1654388:EL116 RS02360
gene id: 1654388:EL116_RS02360
uniprot id: A0A2K4AIE1
names: Function
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1654388:EL116 RS04455
gene id: 1654388:EL116_RS04455
uniprot id: A0A2K4AM82
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1654388:EL116 RS10945
gene id: 1654388:EL116_RS10945
uniprot id: A0A2K4AJU9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS07665
gene id: 1654388:EL116_RS07665
uniprot id: A0A2K4AGP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS01505
gene id: 1654388:EL116_RS01505
uniprot id: A0A2K4AIW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS00340
gene id: 1654388:EL116_RS00340
uniprot id: A0A3S5E717
names: Similarity
names: Subunit
messages: Belongs to the immunoglobulin-binding protein SpA family.
messages: Interacts with host TNFRSF1A; this interaction leads to the stimulation of both surface expression and shedding of TNFRSF1A.

1654388:EL116 RS03395
gene id: 1654388:EL116_RS03395
uniprot id: A0A2K4AKJ1
names: Similarity
messages: Belongs to the LOG family.

1654388:EL116 RS02920
gene id: 1654388:EL116_RS02920
uniprot id: A0A2K4AEM9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS07545
gene id: 1654388:EL116_RS07545
uniprot id: A0A2K4AIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1654388:EL116 RS08405
gene id: 1654388:EL116_RS08405
uniprot id: A0A2K4AGL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1654388:EL116 RS00570
gene id: 1654388:EL116_RS00570
uniprot id: A0A2K4AMF0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1654388:EL116 RS07840
gene id: 1654388:EL116_RS07840
uniprot id: A0A2K4AGB7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1654388:EL116 RS13130
gene id: 1654388:EL116_RS13130
uniprot id: A0A2K4AH68
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1654388:EL116 RS01015
gene id: 1654388:EL116_RS01015
uniprot id: A0A2K4AH25
names: Function
names: Subunit
messages: Homodimer or homotrimer. Seems to be a monomer when not phosphorylated.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1654388:EL116 RS05960
gene id: 1654388:EL116_RS05960
uniprot id: A0A2K4AEH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1654388:EL116 RS00030
gene id: 1654388:EL116_RS00030
uniprot id: A0A2K4AP18
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1654388:EL116 RS10240
gene id: 1654388:EL116_RS10240
uniprot id: A0A2K4AJ24
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS05470
gene id: 1654388:EL116_RS05470
uniprot id: A0A2K4AL74
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS00955
gene id: 1654388:EL116_RS00955
uniprot id: A0A2K4AJM6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1654388:EL116 RS04585
gene id: 1654388:EL116_RS04585
uniprot id: A0A2K4AJJ2
names: Caution
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS03230
gene id: 1654388:EL116_RS03230
uniprot id: A0A2K4AE93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1654388:EL116 RS10850
gene id: 1654388:EL116_RS10850
uniprot id: A0A2K4AJN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multidrug resistance efflux pump SepA family.
messages: Cell membrane
messages: Involved in multidrug efflux.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS07045
gene id: 1654388:EL116_RS07045
uniprot id: A0A2K4AI46
names: Similarity
messages: Belongs to the TrpC family.

1654388:EL116 RS11040
gene id: 1654388:EL116_RS11040
uniprot id: A0A2K4AJP9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS06470
gene id: 1654388:EL116_RS06470
uniprot id: A0A077VWZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback-inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation. Under conditions of nitrogen excess, feedback-inhibited GlnA forms a stable complex with TnrA, which inhibits its DNA-binding activity. In contrast, feedback-inhibited GlnA acts as a chaperone to stabilize the DNA-binding activity of GlnR, which represses the transcription of nitrogen assimilation genes.
messages: Oligomer of 12 subunits arranged in the form of two hexagons. In its feedback-inhibited form, interacts with TnrA in order to block its DNA-binding activity.

1654388:EL116 RS04900
gene id: 1654388:EL116_RS04900
uniprot id: A0A2K4AKF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
messages: Belongs to the SpxH family.
messages: Cytoplasm
messages: Interacts with Spx.

1654388:EL116 RS12145
gene id: 1654388:EL116_RS12145
uniprot id: A0A2K4AFR7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS08925
gene id: 1654388:EL116_RS08925
uniprot id: A0A2K4AFT7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1654388:EL116 RS10910
gene id: 1654388:EL116_RS10910
uniprot id: A0A2K4AKM4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS05255
gene id: 1654388:EL116_RS05255
uniprot id: A0A2K4AKZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1654388:EL116 RS08410
gene id: 1654388:EL116_RS08410
uniprot id: A0A2K4AGM8
names: Similarity
messages: Belongs to the RecJ family.

1654388:EL116 RS03875
gene id: 1654388:EL116_RS03875
uniprot id: A0A2K4AK07
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1654388:EL116 RS09930
gene id: 1654388:EL116_RS09930
uniprot id: A0A2K4AJA9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1654388:EL116 RS08940
gene id: 1654388:EL116_RS08940
uniprot id: A0A2K4AFE5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS10655
gene id: 1654388:EL116_RS10655
uniprot id: A0A2K4AFA2
names: Similarity
messages: Belongs to the peptidase M20A family.

1654388:EL116 RS11220
gene id: 1654388:EL116_RS11220
uniprot id: A0A077UGW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1654388:EL116 RS04450
gene id: 1654388:EL116_RS04450
uniprot id: A0A2K4AM50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1654388:EL116 RS00385
gene id: 1654388:EL116_RS00385
uniprot id: A0A2K4AMW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS12840
gene id: 1654388:EL116_RS12840
uniprot id: A0A2K4ALV5
names: Similarity
messages: Belongs to the staphylococcal/streptococcal toxin family.

1654388:EL116 RS12350
gene id: 1654388:EL116_RS12350
uniprot id: A0A2K4AFM8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1654388:EL116 RS01370
gene id: 1654388:EL116_RS01370
uniprot id: A0A2K4AII0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. HrtA family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

1654388:EL116 RS11850
gene id: 1654388:EL116_RS11850
uniprot id: A0A2K4AFU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. HrtA family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

1654388:EL116 RS13305
gene id: 1654388:EL116_RS13305
uniprot id: A0A2K4AHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1654388:EL116 RS07120
gene id: 1654388:EL116_RS07120
uniprot id: A0A2K4AIT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1654388:EL116 RS01540
gene id: 1654388:EL116_RS01540
uniprot id: A0A2K4AIS2
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1654388:EL116 RS06940
gene id: 1654388:EL116_RS06940
uniprot id: A0A2K4AI68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1654388:EL116 RS11200
gene id: 1654388:EL116_RS11200
uniprot id: A0A2K4AM29
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1654388:EL116 RS03720
gene id: 1654388:EL116_RS03720
uniprot id: A0A2K4AJZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1654388:EL116 RS03675
gene id: 1654388:EL116_RS03675
uniprot id: A0A2K4AK04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for heme-iron. Responsible for the translocation of the substrate across the membrane.

1654388:EL116 RS05825
gene id: 1654388:EL116_RS05825
uniprot id: A0A2K4ADL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS10605
gene id: 1654388:EL116_RS10605
uniprot id: A0A2K4AF90
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS04895
gene id: 1654388:EL116_RS04895
uniprot id: A0A2K4AK92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1654388:EL116 RS12180
gene id: 1654388:EL116_RS12180
uniprot id: A0A2K4AFM4
names: Similarity
messages: Belongs to the aerolysin family.

1654388:EL116 RS10115
gene id: 1654388:EL116_RS10115
uniprot id: A0A2K4AJ46
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1654388:EL116 RS09840
gene id: 1654388:EL116_RS09840
uniprot id: A0A2K4AJC8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1654388:EL116 RS06130
gene id: 1654388:EL116_RS06130
uniprot id: A0A2K4ADW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1654388:EL116 RS08165
gene id: 1654388:EL116_RS08165
uniprot id: A0A2K4AGG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1654388:EL116 RS07745
gene id: 1654388:EL116_RS07745
uniprot id: A0A2K4AH56
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1654388:EL116 RS03220
gene id: 1654388:EL116_RS03220
uniprot id: A0A2K4AF41
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS12335
gene id: 1654388:EL116_RS12335
uniprot id: A0A2K4AFR5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS02715
gene id: 1654388:EL116_RS02715
uniprot id: A0A2K4AEK5
names: Similarity
messages: Belongs to the DCK/DGK family.

1654388:EL116 RS03200
gene id: 1654388:EL116_RS03200
uniprot id: A0A2K4AEN0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1654388:EL116 RS04875
gene id: 1654388:EL116_RS04875
uniprot id: A0A2K4AKA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1654388:EL116 RS07330
gene id: 1654388:EL116_RS07330
uniprot id: A0A2K4AHQ7
names: Function
messages: May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

1654388:EL116 RS13550
gene id: 1654388:EL116_RS13550
uniprot id: A0A2K4ANW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1654388:EL116 RS07960
gene id: 1654388:EL116_RS07960
uniprot id: A0A2K4AGG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1654388:EL116 RS10855
gene id: 1654388:EL116_RS10855
uniprot id: A0A2K4AJL7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1654388:EL116 RS05755
gene id: 1654388:EL116_RS05755
uniprot id: A0A3S4P7G4
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS10935
gene id: 1654388:EL116_RS10935
uniprot id: A0A2K4AJN1
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS10215
gene id: 1654388:EL116_RS10215
uniprot id: A0A2K4AJ61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS03615
gene id: 1654388:EL116_RS03615
uniprot id: A0A2K4AJX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

1654388:EL116 RS03210
gene id: 1654388:EL116_RS03210
uniprot id: A0A2K4AEC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1654388:EL116 RS12915
gene id: 1654388:EL116_RS12915
uniprot id: A0A2K4AH39
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1654388:EL116 RS12505
gene id: 1654388:EL116_RS12505
uniprot id: A0A2K4AFN3
names: Similarity
messages: Belongs to the staphylococcal tandem lipoprotein family.

1654388:EL116 RS03755
gene id: 1654388:EL116_RS03755
uniprot id: A0A2K4AK12
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS04470
gene id: 1654388:EL116_RS04470
uniprot id: A0A2K4AM61
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1654388:EL116 RS05260
gene id: 1654388:EL116_RS05260
uniprot id: A0A2K4AL00
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

1654388:EL116 RS11170
gene id: 1654388:EL116_RS11170
uniprot id: A0A077UGV8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1654388:EL116 RS09800
gene id: 1654388:EL116_RS09800
uniprot id: A0A2K4AJJ9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS07920
gene id: 1654388:EL116_RS07920
uniprot id: A0A2K4AGU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1654388:EL116 RS08050
gene id: 1654388:EL116_RS08050
uniprot id: A0A077VYC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1654388:EL116 RS10955
gene id: 1654388:EL116_RS10955
uniprot id: A0A2K4AJJ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1654388:EL116 RS03740
gene id: 1654388:EL116_RS03740
uniprot id: A0A2K4AJY1
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS00370
gene id: 1654388:EL116_RS00370
uniprot id: A0A2K4AMZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. SbnA subfamily.
messages: Catalyzes the synthesis of N-((2S)-2-amino-2-carboxyethyl)-L-glutamate (ACEGA) from O-phospho-L-serine and L-glutamate. Involved in the biosynthesis of L-2,3-diaminopropionic acid (L-Dap), a precursor of staphyloferrin B and antibiotics.
messages: Homodimer.

1654388:EL116 RS07100
gene id: 1654388:EL116_RS07100
uniprot id: A0A2K4AI39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS11855
gene id: 1654388:EL116_RS11855
uniprot id: A0A2K4AFV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. HrtB subfamily.
messages: Membrane
messages: Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (HrtA), two transmembrane proteins (HrtB) and a solute-binding protein.

1654388:EL116 RS06455
gene id: 1654388:EL116_RS06455
uniprot id: A0A2K4AE24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1654388:EL116 RS08445
gene id: 1654388:EL116_RS08445
uniprot id: A0A2K4AH26
names: Similarity
messages: Belongs to the UPF0735 family.

1654388:EL116 RS05225
gene id: 1654388:EL116_RS05225
uniprot id: A0A2K4ALY9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS10560
gene id: 1654388:EL116_RS10560
uniprot id: A0A2K4AES5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1654388:EL116 RS00750
gene id: 1654388:EL116_RS00750
uniprot id: A0A2K4AML8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1654388:EL116 RS02500
gene id: 1654388:EL116_RS02500
uniprot id: A0A2K4AJJ2
names: Caution
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS13340
gene id: 1654388:EL116_RS13340
uniprot id: A0A2K4AHA5
names: Subcellular Location Annotation
messages: Membrane

1654388:EL116 RS10485
gene id: 1654388:EL116_RS10485
uniprot id: A0A2K4AEW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS11900
gene id: 1654388:EL116_RS11900
uniprot id: A0A2K4AFT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1654388:EL116 RS12395
gene id: 1654388:EL116_RS12395
uniprot id: A0A2K4AFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS11500
gene id: 1654388:EL116_RS11500
uniprot id: A0A2K4ALT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1654388:EL116 RS01560
gene id: 1654388:EL116_RS01560
uniprot id: A0A2K4AIQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS02925
gene id: 1654388:EL116_RS02925
uniprot id: A0A2K4AEH5
names: Similarity
messages: In the N-terminal section; belongs to the LXG family.

1654388:EL116 RS07570
gene id: 1654388:EL116_RS07570
uniprot id: W8U5T9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1654388:EL116 RS09830
gene id: 1654388:EL116_RS09830
uniprot id: A0A2K4AJB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1654388:EL116 RS08020
gene id: 1654388:EL116_RS08020
uniprot id: A0A2K4AGP8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS03450
gene id: 1654388:EL116_RS03450
uniprot id: A0A2K4AKU0
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1654388:EL116 RS13800
gene id: 1654388:EL116_RS13800
uniprot id: A0A2K4AJK5
names: Similarity
names: Subunit
messages: Belongs to the LacAB/RpiB family.
messages: Heteromultimeric protein consisting of LacA and LacB.

1654388:EL116 RS11610
gene id: 1654388:EL116_RS11610
uniprot id: A0A2K4AGF8
names: Function
messages: Repressor of the lactose catabolism operon. Galactose-6-phosphate is the inducer.

1654388:EL116 RS08200
gene id: 1654388:EL116_RS08200
uniprot id: A0A2K4AGH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1654388:EL116 RS08905
gene id: 1654388:EL116_RS08905
uniprot id: A0A2K4AFC0
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1654388:EL116 RS10675
gene id: 1654388:EL116_RS10675
uniprot id: A0A448CY23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1654388:EL116 RS12755
gene id: 1654388:EL116_RS12755
uniprot id: A0A2K4ALL6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1654388:EL116 RS03075
gene id: 1654388:EL116_RS03075
uniprot id: A0A2K4AEB5
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

1654388:EL116 RS04715
gene id: 1654388:EL116_RS04715
uniprot id: A0A2K4ALA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS05655
gene id: 1654388:EL116_RS05655
uniprot id: A0A2K4ADG6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1654388:EL116 RS13620
gene id: 1654388:EL116_RS13620
uniprot id: A0A2K4ANZ9
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1654388:EL116 RS01120
gene id: 1654388:EL116_RS01120
uniprot id: A0A2K4AI63
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1654388:EL116 RS08570
gene id: 1654388:EL116_RS08570
uniprot id: A0A2K4AGQ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1654388:EL116 RS10905
gene id: 1654388:EL116_RS10905
uniprot id: A0A2K4AJK7
names: Similarity
messages: Belongs to the IucA/IucC family.

1654388:EL116 RS08450
gene id: 1654388:EL116_RS08450
uniprot id: A0A2K4AGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1654388:EL116 RS04855
gene id: 1654388:EL116_RS04855
uniprot id: A0A2K4AKH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS06745
gene id: 1654388:EL116_RS06745
uniprot id: A0A2K4AJJ2
names: Caution
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS09350
gene id: 1654388:EL116_RS09350
uniprot id: A0A2K4AF69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

1654388:EL116 RS01715
gene id: 1654388:EL116_RS01715
uniprot id: A0A2K4AIR9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

1654388:EL116 RS10840
gene id: 1654388:EL116_RS10840
uniprot id: A0A2K4AJY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1654388:EL116 RS08535
gene id: 1654388:EL116_RS08535
uniprot id: A0A2K4AGS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1654388:EL116 RS00870
gene id: 1654388:EL116_RS00870
uniprot id: A0A2K4AMN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1654388:EL116 RS01335
gene id: 1654388:EL116_RS01335
uniprot id: A0A2K4AJL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1654388:EL116 RS00580
gene id: 1654388:EL116_RS00580
uniprot id: A0A2K4AMH8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1654388:EL116 RS01200
gene id: 1654388:EL116_RS01200
uniprot id: W8TSE3
names: Similarity
messages: Belongs to the WXG100 family.

1654388:EL116 RS11935
gene id: 1654388:EL116_RS11935
uniprot id: A0A2K4AFV7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1654388:EL116 RS01720
gene id: 1654388:EL116_RS01720
uniprot id: A0A2K4AIV0
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.