1642646:ING2E5A RS13450
gene id: 1642646:ING2E5A_RS13450
uniprot id: A0A1G4GAK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1642646:ING2E5A RS02330
gene id: 1642646:ING2E5A_RS02330
uniprot id: A0A1G4G486
names: Similarity
messages: Belongs to the Skp family.

1642646:ING2E5A RS11390
gene id: 1642646:ING2E5A_RS11390
uniprot id: A0A1G4G9F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1642646:ING2E5A RS08070
gene id: 1642646:ING2E5A_RS08070
uniprot id: A0A1G4G7I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1642646:ING2E5A RS14235
gene id: 1642646:ING2E5A_RS14235
uniprot id: A0A1G4GB11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1642646:ING2E5A RS08440
gene id: 1642646:ING2E5A_RS08440
uniprot id: A0A1G4G7Q5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1642646:ING2E5A RS08130
gene id: 1642646:ING2E5A_RS08130
uniprot id: A0A1G4G7J9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1642646:ING2E5A RS11335
gene id: 1642646:ING2E5A_RS11335
uniprot id: A0A1G4G9D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1642646:ING2E5A RS06140
gene id: 1642646:ING2E5A_RS06140
uniprot id: A0A1G4G6J2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS02920
gene id: 1642646:ING2E5A_RS02920
uniprot id: A0A1G4G4H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1642646:ING2E5A RS09135
gene id: 1642646:ING2E5A_RS09135
uniprot id: A0A1G4G894
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1642646:ING2E5A RS14705
gene id: 1642646:ING2E5A_RS14705
uniprot id: A0A1G4GBC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1642646:ING2E5A RS00465
gene id: 1642646:ING2E5A_RS00465
uniprot id: A0A1G4G336
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1642646:ING2E5A RS05230
gene id: 1642646:ING2E5A_RS05230
uniprot id: A0A1G4G5X6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1642646:ING2E5A RS10385
gene id: 1642646:ING2E5A_RS10385
uniprot id: A0A1G4G5E7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1642646:ING2E5A RS15530
gene id: 1642646:ING2E5A_RS15530
uniprot id: A0A1G4G9T8
names: Similarity
messages: Belongs to the peptidase C40 family.

1642646:ING2E5A RS12035
gene id: 1642646:ING2E5A_RS12035
uniprot id: A0A1G4G9R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1642646:ING2E5A RS05615
gene id: 1642646:ING2E5A_RS05615
uniprot id: A0A1G4G639
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1642646:ING2E5A RS12755
gene id: 1642646:ING2E5A_RS12755
uniprot id: A0A1G4GA60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1642646:ING2E5A RS03965
gene id: 1642646:ING2E5A_RS03965
uniprot id: A0A1G4G5B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1642646:ING2E5A RS13145
gene id: 1642646:ING2E5A_RS13145
uniprot id: A0A1G4GAF6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1642646:ING2E5A RS05380
gene id: 1642646:ING2E5A_RS05380
uniprot id: A0A1G4G5Z0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1642646:ING2E5A RS11100
gene id: 1642646:ING2E5A_RS11100
uniprot id: A0A1G4G980
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1642646:ING2E5A RS06830
gene id: 1642646:ING2E5A_RS06830
uniprot id: A0A1G4G6W0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1642646:ING2E5A RS09060
gene id: 1642646:ING2E5A_RS09060
uniprot id: A0A1G4G841
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1642646:ING2E5A RS00550
gene id: 1642646:ING2E5A_RS00550
uniprot id: A0A1G4G361
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1642646:ING2E5A RS07840
gene id: 1642646:ING2E5A_RS07840
uniprot id: A0A1G4G7F2
names: Similarity
messages: Belongs to the transketolase family.

1642646:ING2E5A RS13395
gene id: 1642646:ING2E5A_RS13395
uniprot id: A0A1G4GAJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1642646:ING2E5A RS10665
gene id: 1642646:ING2E5A_RS10665
uniprot id: A0A1G4G909
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1642646:ING2E5A RS12855
gene id: 1642646:ING2E5A_RS12855
uniprot id: A0A1G4GA82
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1642646:ING2E5A RS04095
gene id: 1642646:ING2E5A_RS04095
uniprot id: A0A1G4G572
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS06245
gene id: 1642646:ING2E5A_RS06245
uniprot id: A0A1G4G6K8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS06410
gene id: 1642646:ING2E5A_RS06410
uniprot id: A0A1G4G6J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1642646:ING2E5A RS07275
gene id: 1642646:ING2E5A_RS07275
uniprot id: A0A1G4G797
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1642646:ING2E5A RS01300
gene id: 1642646:ING2E5A_RS01300
uniprot id: A0A1G4G3J8
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

1642646:ING2E5A RS01480
gene id: 1642646:ING2E5A_RS01480
uniprot id: A0A1G4G3R2
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS05460
gene id: 1642646:ING2E5A_RS05460
uniprot id: A0A1G4G612
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1642646:ING2E5A RS08915
gene id: 1642646:ING2E5A_RS08915
uniprot id: A0A1G4G811
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1642646:ING2E5A RS08910
gene id: 1642646:ING2E5A_RS08910
uniprot id: A0A1G4G7Z4
names: Similarity
messages: Belongs to the YicC/YloC family.

1642646:ING2E5A RS11340
gene id: 1642646:ING2E5A_RS11340
uniprot id: A0A1G4G9D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1642646:ING2E5A RS14420
gene id: 1642646:ING2E5A_RS14420
uniprot id: A0A1G4GB50
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS11580
gene id: 1642646:ING2E5A_RS11580
uniprot id: A0A1G4G9I0
names: Similarity
messages: Belongs to the pirin family.

1642646:ING2E5A RS06970
gene id: 1642646:ING2E5A_RS06970
uniprot id: A0A1G4G6W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1642646:ING2E5A RS03315
gene id: 1642646:ING2E5A_RS03315
uniprot id: A0A1G4G4U1
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1642646:ING2E5A RS14135
gene id: 1642646:ING2E5A_RS14135
uniprot id: A0A1G4GB45
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS02455
gene id: 1642646:ING2E5A_RS02455
uniprot id: A0A1G4G4F7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1642646:ING2E5A RS13540
gene id: 1642646:ING2E5A_RS13540
uniprot id: A0A1G4GAM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1642646:ING2E5A RS08085
gene id: 1642646:ING2E5A_RS08085
uniprot id: A0A1G4G7K3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1642646:ING2E5A RS09695
gene id: 1642646:ING2E5A_RS09695
uniprot id: A0A1G4G8I1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

1642646:ING2E5A RS13030
gene id: 1642646:ING2E5A_RS13030
uniprot id: A0A1G4GAC7
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS05325
gene id: 1642646:ING2E5A_RS05325
uniprot id: A0A1G4G690
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1642646:ING2E5A RS11270
gene id: 1642646:ING2E5A_RS11270
uniprot id: A0A1G4G9G0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1642646:ING2E5A RS00425
gene id: 1642646:ING2E5A_RS00425
uniprot id: A0A1G4G359
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1642646:ING2E5A RS07875
gene id: 1642646:ING2E5A_RS07875
uniprot id: A0A1G4G7E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1642646:ING2E5A RS08005
gene id: 1642646:ING2E5A_RS08005
uniprot id: A0A1G4G7K0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1642646:ING2E5A RS09045
gene id: 1642646:ING2E5A_RS09045
uniprot id: A0A1G4G847
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS04645
gene id: 1642646:ING2E5A_RS04645
uniprot id: A0A1G4G5N7
names: Similarity
messages: Belongs to the UPF0251 family.

1642646:ING2E5A RS07685
gene id: 1642646:ING2E5A_RS07685
uniprot id: A0A1G4G7A6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS05355
gene id: 1642646:ING2E5A_RS05355
uniprot id: A0A1G4G5X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1642646:ING2E5A RS12215
gene id: 1642646:ING2E5A_RS12215
uniprot id: A0A1G4G9V5
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS06655
gene id: 1642646:ING2E5A_RS06655
uniprot id: A0A1G4G6R5
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS11595
gene id: 1642646:ING2E5A_RS11595
uniprot id: A0A1G4G9L7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1642646:ING2E5A RS01205
gene id: 1642646:ING2E5A_RS01205
uniprot id: A0A1G4G3N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1642646:ING2E5A RS02035
gene id: 1642646:ING2E5A_RS02035
uniprot id: A0A1G4G410
names: Similarity
messages: Belongs to the UPF0758 family.

1642646:ING2E5A RS11070
gene id: 1642646:ING2E5A_RS11070
uniprot id: A0A1G4G979
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS00830
gene id: 1642646:ING2E5A_RS00830
uniprot id: A0A1G4G3A7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1642646:ING2E5A RS08180
gene id: 1642646:ING2E5A_RS08180
uniprot id: A0A1G4G7K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1642646:ING2E5A RS11590
gene id: 1642646:ING2E5A_RS11590
uniprot id: A0A1G4G9N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1642646:ING2E5A RS02630
gene id: 1642646:ING2E5A_RS02630
uniprot id: A0A1G4G4C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1642646:ING2E5A RS08025
gene id: 1642646:ING2E5A_RS08025
uniprot id: A0A1G4G7K7
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS12320
gene id: 1642646:ING2E5A_RS12320
uniprot id: A0A1G4GA27
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS05870
gene id: 1642646:ING2E5A_RS05870
uniprot id: A0A1G4G686
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1642646:ING2E5A RS04125
gene id: 1642646:ING2E5A_RS04125
uniprot id: A0A1G4G583
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS07715
gene id: 1642646:ING2E5A_RS07715
uniprot id: A0A1G4G7B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1642646:ING2E5A RS11365
gene id: 1642646:ING2E5A_RS11365
uniprot id: A0A1G4G9H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1642646:ING2E5A RS01285
gene id: 1642646:ING2E5A_RS01285
uniprot id: A0A1G4G3J7
names: Similarity
messages: Belongs to the DEAD box helicase family.

1642646:ING2E5A RS08325
gene id: 1642646:ING2E5A_RS08325
uniprot id: A0A1G4G7P3
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1642646:ING2E5A RS06045
gene id: 1642646:ING2E5A_RS06045
uniprot id: A0A1G4G6H5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1642646:ING2E5A RS05770
gene id: 1642646:ING2E5A_RS05770
uniprot id: A0A1G4G665
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS00020
gene id: 1642646:ING2E5A_RS00020
uniprot id: A0A1G4G2S0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1642646:ING2E5A RS05130
gene id: 1642646:ING2E5A_RS05130
uniprot id: A0A1G4G5V4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1642646:ING2E5A RS13515
gene id: 1642646:ING2E5A_RS13515
uniprot id: A0A1G4GAR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1642646:ING2E5A RS11865
gene id: 1642646:ING2E5A_RS11865
uniprot id: A0A1G4G9U1
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1642646:ING2E5A RS00240
gene id: 1642646:ING2E5A_RS00240
uniprot id: A0A1G4G2Z3
names: Similarity
messages: Belongs to the NusB family.

1642646:ING2E5A RS12885
gene id: 1642646:ING2E5A_RS12885
uniprot id: A0A1G4GA91
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1642646:ING2E5A RS09455
gene id: 1642646:ING2E5A_RS09455
uniprot id: A0A1G4G8A2
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS11575
gene id: 1642646:ING2E5A_RS11575
uniprot id: A0A1G4G9N4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1642646:ING2E5A RS06580
gene id: 1642646:ING2E5A_RS06580
uniprot id: A0A1G4G6V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1642646:ING2E5A RS08475
gene id: 1642646:ING2E5A_RS08475
uniprot id: A0A1G4G7R0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1642646:ING2E5A RS01770
gene id: 1642646:ING2E5A_RS01770
uniprot id: A0A1G4G3U6
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1642646:ING2E5A RS10175
gene id: 1642646:ING2E5A_RS10175
uniprot id: A0A1G4G8S4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS12515
gene id: 1642646:ING2E5A_RS12515
uniprot id: A0A1G4GA15
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1642646:ING2E5A RS04100
gene id: 1642646:ING2E5A_RS04100
uniprot id: A0A1G4G5F1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1642646:ING2E5A RS04950
gene id: 1642646:ING2E5A_RS04950
uniprot id: A0A1G4G5R2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS11095
gene id: 1642646:ING2E5A_RS11095
uniprot id: A0A1G4G9C9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1642646:ING2E5A RS02065
gene id: 1642646:ING2E5A_RS02065
uniprot id: A0A1G4G484
names: Similarity
messages: Belongs to the UPF0246 family.

1642646:ING2E5A RS11620
gene id: 1642646:ING2E5A_RS11620
uniprot id: A0A1G4G9L5
names: Similarity
messages: Belongs to the RutC family.

1642646:ING2E5A RS05150
gene id: 1642646:ING2E5A_RS05150
uniprot id: A0A1G4G5Z4
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS07680
gene id: 1642646:ING2E5A_RS07680
uniprot id: A0A1G4G7A8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1642646:ING2E5A RS04310
gene id: 1642646:ING2E5A_RS04310
uniprot id: A0A1G4G5F5
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1642646:ING2E5A RS10015
gene id: 1642646:ING2E5A_RS10015
uniprot id: A0A1G4G8P9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS01760
gene id: 1642646:ING2E5A_RS01760
uniprot id: A0A1G4G400
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS02235
gene id: 1642646:ING2E5A_RS02235
uniprot id: A0A1G4G444
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1642646:ING2E5A RS05415
gene id: 1642646:ING2E5A_RS05415
uniprot id: A0A1G4G5Y8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1642646:ING2E5A RS09125
gene id: 1642646:ING2E5A_RS09125
uniprot id: A0A1G4G844
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1642646:ING2E5A RS11370
gene id: 1642646:ING2E5A_RS11370
uniprot id: A0A1G4G9D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1642646:ING2E5A RS13080
gene id: 1642646:ING2E5A_RS13080
uniprot id: A0A1G4GAD8
names: Similarity
messages: Belongs to the Skp family.

1642646:ING2E5A RS12845
gene id: 1642646:ING2E5A_RS12845
uniprot id: A0A1G4GAE4
names: Similarity
messages: Belongs to the pyruvate kinase family.

1642646:ING2E5A RS13855
gene id: 1642646:ING2E5A_RS13855
uniprot id: A0A1G4GAX6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1642646:ING2E5A RS14645
gene id: 1642646:ING2E5A_RS14645
uniprot id: A0A1G4GBF3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1642646:ING2E5A RS11735
gene id: 1642646:ING2E5A_RS11735
uniprot id: A0A1G4G9Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1642646:ING2E5A RS14560
gene id: 1642646:ING2E5A_RS14560
uniprot id: A0A1G4GBB4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1642646:ING2E5A RS03690
gene id: 1642646:ING2E5A_RS03690
uniprot id: A0A1G4G4Y4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1642646:ING2E5A RS12740
gene id: 1642646:ING2E5A_RS12740
uniprot id: A0A1G4GA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1642646:ING2E5A RS00015
gene id: 1642646:ING2E5A_RS00015
uniprot id: A0A1G4G334
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1642646:ING2E5A RS08425
gene id: 1642646:ING2E5A_RS08425
uniprot id: A0A1G4G7Q3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1642646:ING2E5A RS14290
gene id: 1642646:ING2E5A_RS14290
uniprot id: A0A1G4GB42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1642646:ING2E5A RS11375
gene id: 1642646:ING2E5A_RS11375
uniprot id: A0A1G4G9G4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1642646:ING2E5A RS05220
gene id: 1642646:ING2E5A_RS05220
uniprot id: A0A1G4G5V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS01230
gene id: 1642646:ING2E5A_RS01230
uniprot id: A0A1G4G3L3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1642646:ING2E5A RS08105
gene id: 1642646:ING2E5A_RS08105
uniprot id: A0A1G4G7I8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1642646:ING2E5A RS04935
gene id: 1642646:ING2E5A_RS04935
uniprot id: A0A1G4G5R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1642646:ING2E5A RS08690
gene id: 1642646:ING2E5A_RS08690
uniprot id: A0A1G4G7V9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1642646:ING2E5A RS10160
gene id: 1642646:ING2E5A_RS10160
uniprot id: A0A1G4G8P5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS00630
gene id: 1642646:ING2E5A_RS00630
uniprot id: A0A1G4G392
names: Similarity
messages: Belongs to the XseB family.

1642646:ING2E5A RS05350
gene id: 1642646:ING2E5A_RS05350
uniprot id: A0A1G4G629
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1642646:ING2E5A RS07695
gene id: 1642646:ING2E5A_RS07695
uniprot id: A0A1G4G7B0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1642646:ING2E5A RS07260
gene id: 1642646:ING2E5A_RS07260
uniprot id: A0A1G4G721
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

1642646:ING2E5A RS02070
gene id: 1642646:ING2E5A_RS02070
uniprot id: A0A1G4G4A2
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS11065
gene id: 1642646:ING2E5A_RS11065
uniprot id: A0A1G4G982
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1642646:ING2E5A RS13465
gene id: 1642646:ING2E5A_RS13465
uniprot id: A0A1G4GAN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1642646:ING2E5A RS07745
gene id: 1642646:ING2E5A_RS07745
uniprot id: A0A1G4G7B8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1642646:ING2E5A RS05040
gene id: 1642646:ING2E5A_RS05040
uniprot id: A0A1G4G5U9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS13510
gene id: 1642646:ING2E5A_RS13510
uniprot id: A0A1G4GAP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1642646:ING2E5A RS01465
gene id: 1642646:ING2E5A_RS01465
uniprot id: A0A1G4G3N8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1642646:ING2E5A RS07490
gene id: 1642646:ING2E5A_RS07490
uniprot id: A0A1G4G7A2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1642646:ING2E5A RS03000
gene id: 1642646:ING2E5A_RS03000
uniprot id: A0A1G4G4P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1642646:ING2E5A RS14820
gene id: 1642646:ING2E5A_RS14820
uniprot id: A0A1G4GBC9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1642646:ING2E5A RS05765
gene id: 1642646:ING2E5A_RS05765
uniprot id: A0A1G4G654
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1642646:ING2E5A RS11160
gene id: 1642646:ING2E5A_RS11160
uniprot id: A0A1G4G9E2
names: Similarity
messages: Belongs to the fabD family.

1642646:ING2E5A RS11325
gene id: 1642646:ING2E5A_RS11325
uniprot id: A0A1G4G9F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1642646:ING2E5A RS08595
gene id: 1642646:ING2E5A_RS08595
uniprot id: A0A1G4G7V3
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

1642646:ING2E5A RS02150
gene id: 1642646:ING2E5A_RS02150
uniprot id: A0A1G4G417
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1642646:ING2E5A RS03190
gene id: 1642646:ING2E5A_RS03190
uniprot id: A0A1G4G4M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1642646:ING2E5A RS06715
gene id: 1642646:ING2E5A_RS06715
uniprot id: A0A1G4G6U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1642646:ING2E5A RS02970
gene id: 1642646:ING2E5A_RS02970
uniprot id: A0A1G4G4I4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1642646:ING2E5A RS02100
gene id: 1642646:ING2E5A_RS02100
uniprot id: A0A1G4G420
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1642646:ING2E5A RS08815
gene id: 1642646:ING2E5A_RS08815
uniprot id: A0A1G4G802
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1642646:ING2E5A RS05480
gene id: 1642646:ING2E5A_RS05480
uniprot id: A0A1G4G611
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1642646:ING2E5A RS13125
gene id: 1642646:ING2E5A_RS13125
uniprot id: A0A1G4GAI9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1642646:ING2E5A RS11605
gene id: 1642646:ING2E5A_RS11605
uniprot id: A0A1G4G9J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1642646:ING2E5A RS03405
gene id: 1642646:ING2E5A_RS03405
uniprot id: A0A1G4G4T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1642646:ING2E5A RS11905
gene id: 1642646:ING2E5A_RS11905
uniprot id: A0A1G4G9Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1642646:ING2E5A RS14785
gene id: 1642646:ING2E5A_RS14785
uniprot id: A0A1G4GBC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1642646:ING2E5A RS14515
gene id: 1642646:ING2E5A_RS14515
uniprot id: A0A1G4GBE8
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS03170
gene id: 1642646:ING2E5A_RS03170
uniprot id: A0A1G4G4T7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1642646:ING2E5A RS08450
gene id: 1642646:ING2E5A_RS08450
uniprot id: A0A1G4G7W7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1642646:ING2E5A RS08510
gene id: 1642646:ING2E5A_RS08510
uniprot id: A0A1G4G7T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1642646:ING2E5A RS02135
gene id: 1642646:ING2E5A_RS02135
uniprot id: A0A1G4G439
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS11005
gene id: 1642646:ING2E5A_RS11005
uniprot id: A0A1G4G988
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1642646:ING2E5A RS12745
gene id: 1642646:ING2E5A_RS12745
uniprot id: A0A1G4GAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1642646:ING2E5A RS07600
gene id: 1642646:ING2E5A_RS07600
uniprot id: A0A1G4G7F5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1642646:ING2E5A RS04885
gene id: 1642646:ING2E5A_RS04885
uniprot id: A0A1G4G5Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1642646:ING2E5A RS14680
gene id: 1642646:ING2E5A_RS14680
uniprot id: A0A1G4GB95
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS03895
gene id: 1642646:ING2E5A_RS03895
uniprot id: A0A1G4G5A1
names: Similarity
messages: Belongs to the DapA family.

1642646:ING2E5A RS11385
gene id: 1642646:ING2E5A_RS11385
uniprot id: A0A1G4G9E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1642646:ING2E5A RS01510
gene id: 1642646:ING2E5A_RS01510
uniprot id: A0A1G4G3Z1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1642646:ING2E5A RS03505
gene id: 1642646:ING2E5A_RS03505
uniprot id: A0A1G4G4Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1642646:ING2E5A RS03040
gene id: 1642646:ING2E5A_RS03040
uniprot id: A0A1G4G4N0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1642646:ING2E5A RS07830
gene id: 1642646:ING2E5A_RS07830
uniprot id: A0A1G4G7D7
names: Similarity
messages: Belongs to the CarB family.

1642646:ING2E5A RS02085
gene id: 1642646:ING2E5A_RS02085
uniprot id: A0A1G4G419
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS03780
gene id: 1642646:ING2E5A_RS03780
uniprot id: A0A1G4G505
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS04940
gene id: 1642646:ING2E5A_RS04940
uniprot id: A0A1G4G5U5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS06625
gene id: 1642646:ING2E5A_RS06625
uniprot id: A0A1G4G6N6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1642646:ING2E5A RS06700
gene id: 1642646:ING2E5A_RS06700
uniprot id: A0A1G4G6V2
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS11460
gene id: 1642646:ING2E5A_RS11460
uniprot id: A0A1G4G9G9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS08195
gene id: 1642646:ING2E5A_RS08195
uniprot id: A0A1G4G7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1642646:ING2E5A RS07240
gene id: 1642646:ING2E5A_RS07240
uniprot id: A0A1G4G730
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1642646:ING2E5A RS08350
gene id: 1642646:ING2E5A_RS08350
uniprot id: A0A1G4G7R6
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1642646:ING2E5A RS05265
gene id: 1642646:ING2E5A_RS05265
uniprot id: A0A1G4G5X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1642646:ING2E5A RS06460
gene id: 1642646:ING2E5A_RS06460
uniprot id: A0A1G4G6K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1642646:ING2E5A RS14195
gene id: 1642646:ING2E5A_RS14195
uniprot id: A0A1G4GB09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1642646:ING2E5A RS02990
gene id: 1642646:ING2E5A_RS02990
uniprot id: A0A1G4G4M2
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS03450
gene id: 1642646:ING2E5A_RS03450
uniprot id: A0A1G4G513
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS10585
gene id: 1642646:ING2E5A_RS10585
uniprot id: A0A1G4G916
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1642646:ING2E5A RS03970
gene id: 1642646:ING2E5A_RS03970
uniprot id: A0A1G4G545
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1642646:ING2E5A RS12420
gene id: 1642646:ING2E5A_RS12420
uniprot id: A0A1G4GA55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1642646:ING2E5A RS13455
gene id: 1642646:ING2E5A_RS13455
uniprot id: A0A1G4GAR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1642646:ING2E5A RS08925
gene id: 1642646:ING2E5A_RS08925
uniprot id: A0A1G4G821
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS06220
gene id: 1642646:ING2E5A_RS06220
uniprot id: A0A1G4G6P6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS12390
gene id: 1642646:ING2E5A_RS12390
uniprot id: A0A1G4G9Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1642646:ING2E5A RS08590
gene id: 1642646:ING2E5A_RS08590
uniprot id: A0A1G4G7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS01200
gene id: 1642646:ING2E5A_RS01200
uniprot id: A0A1G4G3I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1642646:ING2E5A RS06720
gene id: 1642646:ING2E5A_RS06720
uniprot id: A0A1G4G6S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS03085
gene id: 1642646:ING2E5A_RS03085
uniprot id: A0A1G4G4K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1642646:ING2E5A RS11380
gene id: 1642646:ING2E5A_RS11380
uniprot id: A0A1G4G9I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1642646:ING2E5A RS12820
gene id: 1642646:ING2E5A_RS12820
uniprot id: A0A1G4GA84
names: Similarity
messages: Belongs to the nitroreductase family.

1642646:ING2E5A RS08110
gene id: 1642646:ING2E5A_RS08110
uniprot id: A0A1G4G7J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1642646:ING2E5A RS12850
gene id: 1642646:ING2E5A_RS12850
uniprot id: A0A1G4GAA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1642646:ING2E5A RS09895
gene id: 1642646:ING2E5A_RS09895
uniprot id: A0A1G4G8M0
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS11300
gene id: 1642646:ING2E5A_RS11300
uniprot id: A0A1G4G9H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1642646:ING2E5A RS07050
gene id: 1642646:ING2E5A_RS07050
uniprot id: A0A1G4G725
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1642646:ING2E5A RS08140
gene id: 1642646:ING2E5A_RS08140
uniprot id: A0A1G4G7J3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1642646:ING2E5A RS13295
gene id: 1642646:ING2E5A_RS13295
uniprot id: A0A1G4G5E7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1642646:ING2E5A RS08380
gene id: 1642646:ING2E5A_RS08380
uniprot id: A0A1G4G7Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1642646:ING2E5A RS03865
gene id: 1642646:ING2E5A_RS03865
uniprot id: A0A1G4G576
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1642646:ING2E5A RS06170
gene id: 1642646:ING2E5A_RS06170
uniprot id: A0A1G4G6G8
names: Similarity
messages: Belongs to the peptidase M24B family.

1642646:ING2E5A RS05890
gene id: 1642646:ING2E5A_RS05890
uniprot id: A0A1G4G6E3
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1642646:ING2E5A RS08205
gene id: 1642646:ING2E5A_RS08205
uniprot id: A0A1G4G7K5
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1642646:ING2E5A RS14310
gene id: 1642646:ING2E5A_RS14310
uniprot id: A0A1G4GB72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

1642646:ING2E5A RS12185
gene id: 1642646:ING2E5A_RS12185
uniprot id: A0A1G4G9X3
names: Similarity
messages: Belongs to the peptidase U62 family.

1642646:ING2E5A RS02285
gene id: 1642646:ING2E5A_RS02285
uniprot id: A0A1G4G448
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS06745
gene id: 1642646:ING2E5A_RS06745
uniprot id: A0A1G4G6R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1642646:ING2E5A RS07185
gene id: 1642646:ING2E5A_RS07185
uniprot id: A0A1G4G707
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1642646:ING2E5A RS11530
gene id: 1642646:ING2E5A_RS11530
uniprot id: A0A1G4G9G6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1642646:ING2E5A RS13460
gene id: 1642646:ING2E5A_RS13460
uniprot id: A0A1G4GAK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1642646:ING2E5A RS11935
gene id: 1642646:ING2E5A_RS11935
uniprot id: A0A1G4G9V3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1642646:ING2E5A RS10435
gene id: 1642646:ING2E5A_RS10435
uniprot id: A0A1G4G930
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1642646:ING2E5A RS04980
gene id: 1642646:ING2E5A_RS04980
uniprot id: A0A1G4G5S4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1642646:ING2E5A RS07780
gene id: 1642646:ING2E5A_RS07780
uniprot id: A0A1G4G7C5
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1642646:ING2E5A RS11130
gene id: 1642646:ING2E5A_RS11130
uniprot id: A0A1G4G9D7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1642646:ING2E5A RS06290
gene id: 1642646:ING2E5A_RS06290
uniprot id: A0A1G4G6I2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1642646:ING2E5A RS11420
gene id: 1642646:ING2E5A_RS11420
uniprot id: A0A1G4G9E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1642646:ING2E5A RS00315
gene id: 1642646:ING2E5A_RS00315
uniprot id: A0A1G4G323
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS14590
gene id: 1642646:ING2E5A_RS14590
uniprot id: A0A1G4GBA4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1642646:ING2E5A RS14625
gene id: 1642646:ING2E5A_RS14625
uniprot id: A0A1G4GBG8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1642646:ING2E5A RS09070
gene id: 1642646:ING2E5A_RS09070
uniprot id: A0A1G4G846
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1642646:ING2E5A RS13325
gene id: 1642646:ING2E5A_RS13325
uniprot id: A0A1G4GAM7
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS11425
gene id: 1642646:ING2E5A_RS11425
uniprot id: A0A1G4G9H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1642646:ING2E5A RS05295
gene id: 1642646:ING2E5A_RS05295
uniprot id: A0A1G4G5Y6
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS06840
gene id: 1642646:ING2E5A_RS06840
uniprot id: A0A1G4G6T3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1642646:ING2E5A RS13505
gene id: 1642646:ING2E5A_RS13505
uniprot id: A0A1G4GAL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1642646:ING2E5A RS05705
gene id: 1642646:ING2E5A_RS05705
uniprot id: A0A1G4G648
names: Similarity
messages: Belongs to the sigma-54 factor family.

1642646:ING2E5A RS11015
gene id: 1642646:ING2E5A_RS11015
uniprot id: A0A1G4G977
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

1642646:ING2E5A RS10795
gene id: 1642646:ING2E5A_RS10795
uniprot id: A0A1G4G5E7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1642646:ING2E5A RS00410
gene id: 1642646:ING2E5A_RS00410
uniprot id: A0A1G4G3D0
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS14175
gene id: 1642646:ING2E5A_RS14175
uniprot id: A0A1G4GB01
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1642646:ING2E5A RS05425
gene id: 1642646:ING2E5A_RS05425
uniprot id: A0A1G4G605
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1642646:ING2E5A RS12410
gene id: 1642646:ING2E5A_RS12410
uniprot id: A0A1G4G9Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS04475
gene id: 1642646:ING2E5A_RS04475
uniprot id: A0A1G4G5P1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1642646:ING2E5A RS00480
gene id: 1642646:ING2E5A_RS00480
uniprot id: A0A1G4G366
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1642646:ING2E5A RS03365
gene id: 1642646:ING2E5A_RS03365
uniprot id: A0A1G4G4U8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1642646:ING2E5A RS01945
gene id: 1642646:ING2E5A_RS01945
uniprot id: A0A1G4G3Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1642646:ING2E5A RS03890
gene id: 1642646:ING2E5A_RS03890
uniprot id: A0A1G4G574
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1642646:ING2E5A RS04535
gene id: 1642646:ING2E5A_RS04535
uniprot id: A0A1G4G5H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1642646:ING2E5A RS08390
gene id: 1642646:ING2E5A_RS08390
uniprot id: A0A1G4G7S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1642646:ING2E5A RS09445
gene id: 1642646:ING2E5A_RS09445
uniprot id: A0A1G4G8C5
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS00435
gene id: 1642646:ING2E5A_RS00435
uniprot id: A0A1G4G329
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1642646:ING2E5A RS04030
gene id: 1642646:ING2E5A_RS04030
uniprot id: A0A1G4G571
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS00930
gene id: 1642646:ING2E5A_RS00930
uniprot id: A0A1G4G3N2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS06420
gene id: 1642646:ING2E5A_RS06420
uniprot id: A0A1G4G6S6
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1642646:ING2E5A RS09850
gene id: 1642646:ING2E5A_RS09850
uniprot id: A0A1G4G8P7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS15095
gene id: 1642646:ING2E5A_RS15095
uniprot id: A0A1G4G9C8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1642646:ING2E5A RS07510
gene id: 1642646:ING2E5A_RS07510
uniprot id: A0A1G4G7B4
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1642646:ING2E5A RS12105
gene id: 1642646:ING2E5A_RS12105
uniprot id: A0A1G4G9Z4
names: Similarity
messages: Belongs to the LOG family.

1642646:ING2E5A RS04345
gene id: 1642646:ING2E5A_RS04345
uniprot id: A0A1G4G5G7
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1642646:ING2E5A RS10955
gene id: 1642646:ING2E5A_RS10955
uniprot id: A0A1G4G997
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1642646:ING2E5A RS05745
gene id: 1642646:ING2E5A_RS05745
uniprot id: A0A1G4G6A2
names: Similarity
messages: Belongs to the peptidase M16 family.

1642646:ING2E5A RS12425
gene id: 1642646:ING2E5A_RS12425
uniprot id: A0A1G4G9Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS09790
gene id: 1642646:ING2E5A_RS09790
uniprot id: A0A1G4G8J9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1642646:ING2E5A RS10655
gene id: 1642646:ING2E5A_RS10655
uniprot id: A0A1G4G937
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS11515
gene id: 1642646:ING2E5A_RS11515
uniprot id: A0A1G4G9L3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1642646:ING2E5A RS07690
gene id: 1642646:ING2E5A_RS07690
uniprot id: A0A1G4G7C1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1642646:ING2E5A RS12765
gene id: 1642646:ING2E5A_RS12765
uniprot id: A0A1G4GAC6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1642646:ING2E5A RS02845
gene id: 1642646:ING2E5A_RS02845
uniprot id: A0A1G4G4F4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1642646:ING2E5A RS11790
gene id: 1642646:ING2E5A_RS11790
uniprot id: A0A1G4G9K8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1642646:ING2E5A RS10960
gene id: 1642646:ING2E5A_RS10960
uniprot id: A0A1G4G964
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1642646:ING2E5A RS08460
gene id: 1642646:ING2E5A_RS08460
uniprot id: A0A1G4G7S6
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS00470
gene id: 1642646:ING2E5A_RS00470
uniprot id: A0A1G4G350
names: Similarity
messages: Belongs to the threonine synthase family.

1642646:ING2E5A RS12190
gene id: 1642646:ING2E5A_RS12190
uniprot id: A0A1G4GA04
names: Similarity
messages: Belongs to the peptidase U62 family.

1642646:ING2E5A RS08045
gene id: 1642646:ING2E5A_RS08045
uniprot id: A0A1G4G7I7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS06505
gene id: 1642646:ING2E5A_RS06505
uniprot id: A0A1G4G6L9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS04755
gene id: 1642646:ING2E5A_RS04755
uniprot id: A0A1G4G5K8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS04985
gene id: 1642646:ING2E5A_RS04985
uniprot id: A0A1G4G5V6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS05920
gene id: 1642646:ING2E5A_RS05920
uniprot id: A0A1G4G693
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1642646:ING2E5A RS00160
gene id: 1642646:ING2E5A_RS00160
uniprot id: A0A1G4G313
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1642646:ING2E5A RS02650
gene id: 1642646:ING2E5A_RS02650
uniprot id: A0A1G4G4K6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1642646:ING2E5A RS12040
gene id: 1642646:ING2E5A_RS12040
uniprot id: A0A1G4G9U3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS05315
gene id: 1642646:ING2E5A_RS05315
uniprot id: A0A1G4G5Y7
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1642646:ING2E5A RS07250
gene id: 1642646:ING2E5A_RS07250
uniprot id: A0A1G4G742
names: Similarity
messages: Belongs to the creatininase superfamily.

1642646:ING2E5A RS10030
gene id: 1642646:ING2E5A_RS10030
uniprot id: A0A1G4G8S0
names: Similarity
messages: Belongs to the SUI1 family.

1642646:ING2E5A RS11465
gene id: 1642646:ING2E5A_RS11465
uniprot id: A0A1G4G9J7
names: Similarity
messages: Belongs to the asparagine synthetase family.

1642646:ING2E5A RS13585
gene id: 1642646:ING2E5A_RS13585
uniprot id: A0A1G4GAV1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1642646:ING2E5A RS11235
gene id: 1642646:ING2E5A_RS11235
uniprot id: A0A1G4G9F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1642646:ING2E5A RS07755
gene id: 1642646:ING2E5A_RS07755
uniprot id: A0A1G4G7I4
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

1642646:ING2E5A RS07355
gene id: 1642646:ING2E5A_RS07355
uniprot id: A0A1G4G746
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS07610
gene id: 1642646:ING2E5A_RS07610
uniprot id: A0A1G4G788
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1642646:ING2E5A RS12895
gene id: 1642646:ING2E5A_RS12895
uniprot id: A0A1G4GAF5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1642646:ING2E5A RS06335
gene id: 1642646:ING2E5A_RS06335
uniprot id: A0A1G4G6N1
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS09690
gene id: 1642646:ING2E5A_RS09690
uniprot id: A0A1G4G8I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1642646:ING2E5A RS03850
gene id: 1642646:ING2E5A_RS03850
uniprot id: A0A1G4G522
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

1642646:ING2E5A RS12750
gene id: 1642646:ING2E5A_RS12750
uniprot id: A0A1G4GA80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1642646:ING2E5A RS11050
gene id: 1642646:ING2E5A_RS11050
uniprot id: A0A1G4G973
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS00220
gene id: 1642646:ING2E5A_RS00220
uniprot id: A0A1G4G2Z6
names: Similarity
messages: Belongs to the peptidase S41A family.

1642646:ING2E5A RS02615
gene id: 1642646:ING2E5A_RS02615
uniprot id: A0A1G4G4I2
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS12540
gene id: 1642646:ING2E5A_RS12540
uniprot id: A0A1G4GA24
names: Similarity
messages: Belongs to the YciI family.

1642646:ING2E5A RS13170
gene id: 1642646:ING2E5A_RS13170
uniprot id: A0A1G4GAI0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1642646:ING2E5A RS05825
gene id: 1642646:ING2E5A_RS05825
uniprot id: A0A1G4G683
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1642646:ING2E5A RS09735
gene id: 1642646:ING2E5A_RS09735
uniprot id: A0A1G4G8M3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1642646:ING2E5A RS14780
gene id: 1642646:ING2E5A_RS14780
uniprot id: A0A1G4GBC6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1642646:ING2E5A RS01650
gene id: 1642646:ING2E5A_RS01650
uniprot id: A0A1G4G3S2
names: Subcellular Location Annotation
messages: Secreted

1642646:ING2E5A RS12915
gene id: 1642646:ING2E5A_RS12915
uniprot id: A0A1G4GAF4
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1642646:ING2E5A RS07025
gene id: 1642646:ING2E5A_RS07025
uniprot id: A0A1G4G6X3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS00590
gene id: 1642646:ING2E5A_RS00590
uniprot id: A0A1G4G349
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS09770
gene id: 1642646:ING2E5A_RS09770
uniprot id: A0A1G4G8J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1642646:ING2E5A RS14555
gene id: 1642646:ING2E5A_RS14555
uniprot id: A0A1G4GBA1
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1642646:ING2E5A RS00285
gene id: 1642646:ING2E5A_RS00285
uniprot id: A0A1G4G302
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1642646:ING2E5A RS06340
gene id: 1642646:ING2E5A_RS06340
uniprot id: A0A1G4G6J4
names: Similarity
messages: Belongs to the UPF0111 family.

1642646:ING2E5A RS11440
gene id: 1642646:ING2E5A_RS11440
uniprot id: A0A1G4G9G3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS08505
gene id: 1642646:ING2E5A_RS08505
uniprot id: A0A1G4G7R3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1642646:ING2E5A RS06540
gene id: 1642646:ING2E5A_RS06540
uniprot id: A0A1G4G6P7
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS10690
gene id: 1642646:ING2E5A_RS10690
uniprot id: A0A1G4G956
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1642646:ING2E5A RS09605
gene id: 1642646:ING2E5A_RS09605
uniprot id: A0A1G4G8F5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1642646:ING2E5A RS07215
gene id: 1642646:ING2E5A_RS07215
uniprot id: A0A1G4G712
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS08190
gene id: 1642646:ING2E5A_RS08190
uniprot id: A0A1G4G7K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1642646:ING2E5A RS03565
gene id: 1642646:ING2E5A_RS03565
uniprot id: A0A1G4G518
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1642646:ING2E5A RS14205
gene id: 1642646:ING2E5A_RS14205
uniprot id: A0A1G4GB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1642646:ING2E5A RS08930
gene id: 1642646:ING2E5A_RS08930
uniprot id: A0A1G4G810
names: Subunit
messages: Homodimer.

1642646:ING2E5A RS08675
gene id: 1642646:ING2E5A_RS08675
uniprot id: A0A1G4G7V7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1642646:ING2E5A RS08990
gene id: 1642646:ING2E5A_RS08990
uniprot id: A0A1G4G823
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1642646:ING2E5A RS11475
gene id: 1642646:ING2E5A_RS11475
uniprot id: A0A1G4G9I1
names: Similarity
messages: Belongs to the glutamate synthase family.

1642646:ING2E5A RS13625
gene id: 1642646:ING2E5A_RS13625
uniprot id: A0A1G4GAT4
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS03900
gene id: 1642646:ING2E5A_RS03900
uniprot id: A0A1G4G532
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS14455
gene id: 1642646:ING2E5A_RS14455
uniprot id: A0A1G4GB97
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS06200
gene id: 1642646:ING2E5A_RS06200
uniprot id: A0A1G4G6J8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1642646:ING2E5A RS01875
gene id: 1642646:ING2E5A_RS01875
uniprot id: A0A1G4G3W5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

1642646:ING2E5A RS05885
gene id: 1642646:ING2E5A_RS05885
uniprot id: A0A1G4G691
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS01855
gene id: 1642646:ING2E5A_RS01855
uniprot id: A0A1G4G3W3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1642646:ING2E5A RS09925
gene id: 1642646:ING2E5A_RS09925
uniprot id: A0A1G4G8M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS14620
gene id: 1642646:ING2E5A_RS14620
uniprot id: A0A1G4GB86
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1642646:ING2E5A RS02470
gene id: 1642646:ING2E5A_RS02470
uniprot id: A0A1G4G4I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1642646:ING2E5A RS01490
gene id: 1642646:ING2E5A_RS01490
uniprot id: A0A1G4G3N6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1642646:ING2E5A RS06650
gene id: 1642646:ING2E5A_RS06650
uniprot id: A0A1G4G6U1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1642646:ING2E5A RS08605
gene id: 1642646:ING2E5A_RS08605
uniprot id: A0A1G4G7T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS06680
gene id: 1642646:ING2E5A_RS06680
uniprot id: A0A1G4G6T2
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS02915
gene id: 1642646:ING2E5A_RS02915
uniprot id: A0A1G4G4P9
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS05125
gene id: 1642646:ING2E5A_RS05125
uniprot id: A0A1G4G637
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1642646:ING2E5A RS02375
gene id: 1642646:ING2E5A_RS02375
uniprot id: A0A1G4G466
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS07700
gene id: 1642646:ING2E5A_RS07700
uniprot id: A0A1G4G7D8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1642646:ING2E5A RS02050
gene id: 1642646:ING2E5A_RS02050
uniprot id: A0A1G4G414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS04040
gene id: 1642646:ING2E5A_RS04040
uniprot id: A0A1G4G564
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1642646:ING2E5A RS07635
gene id: 1642646:ING2E5A_RS07635
uniprot id: A0A1G4G7A1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1642646:ING2E5A RS06315
gene id: 1642646:ING2E5A_RS06315
uniprot id: A0A1G4G6J5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1642646:ING2E5A RS04220
gene id: 1642646:ING2E5A_RS04220
uniprot id: A0A1G4G5E8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1642646:ING2E5A RS14615
gene id: 1642646:ING2E5A_RS14615
uniprot id: A0A1G4GBB5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1642646:ING2E5A RS00460
gene id: 1642646:ING2E5A_RS00460
uniprot id: A0A1G4G3D3
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1642646:ING2E5A RS03075
gene id: 1642646:ING2E5A_RS03075
uniprot id: A0A1G4G4S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1642646:ING2E5A RS13690
gene id: 1642646:ING2E5A_RS13690
uniprot id: A0A1G4GAQ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS04715
gene id: 1642646:ING2E5A_RS04715
uniprot id: A0A1G4G5N6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS03240
gene id: 1642646:ING2E5A_RS03240
uniprot id: A0A1G4G4Q2
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS11400
gene id: 1642646:ING2E5A_RS11400
uniprot id: A0A1G4G9I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1642646:ING2E5A RS12580
gene id: 1642646:ING2E5A_RS12580
uniprot id: A0A1G4GA85
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS14765
gene id: 1642646:ING2E5A_RS14765
uniprot id: A0A1G4GBF7
names: Similarity
messages: Belongs to the HSP15 family.

1642646:ING2E5A RS06415
gene id: 1642646:ING2E5A_RS06415
uniprot id: A0A1G4G6L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1642646:ING2E5A RS07015
gene id: 1642646:ING2E5A_RS07015
uniprot id: A0A1G4G6Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1642646:ING2E5A RS02295
gene id: 1642646:ING2E5A_RS02295
uniprot id: A0A1G4G468
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1642646:ING2E5A RS12955
gene id: 1642646:ING2E5A_RS12955
uniprot id: A0A1G4GAA7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1642646:ING2E5A RS06180
gene id: 1642646:ING2E5A_RS06180
uniprot id: A0A1G4G6E7
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS03675
gene id: 1642646:ING2E5A_RS03675
uniprot id: A0A1G4G4Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1642646:ING2E5A RS06330
gene id: 1642646:ING2E5A_RS06330
uniprot id: A0A1G4G6L2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1642646:ING2E5A RS09655
gene id: 1642646:ING2E5A_RS09655
uniprot id: A0A1G4G8E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1642646:ING2E5A RS10645
gene id: 1642646:ING2E5A_RS10645
uniprot id: A0A1G4G8Z5
names: Similarity
messages: Belongs to the SufE family.

1642646:ING2E5A RS02925
gene id: 1642646:ING2E5A_RS02925
uniprot id: A0A1G4G4P1
names: Similarity
messages: Belongs to the isochorismate synthase family.

1642646:ING2E5A RS09700
gene id: 1642646:ING2E5A_RS09700
uniprot id: A0A1G4G8L8
names: Similarity
messages: Belongs to the Dps family.

1642646:ING2E5A RS11305
gene id: 1642646:ING2E5A_RS11305
uniprot id: A0A1G4G9G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1642646:ING2E5A RS11940
gene id: 1642646:ING2E5A_RS11940
uniprot id: A0A1G4G9N7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1642646:ING2E5A RS04450
gene id: 1642646:ING2E5A_RS04450
uniprot id: A0A1G4G5J6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1642646:ING2E5A RS04440
gene id: 1642646:ING2E5A_RS04440
uniprot id: A0A1G4G5K1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1642646:ING2E5A RS11725
gene id: 1642646:ING2E5A_RS11725
uniprot id: A0A1G4G9K9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1642646:ING2E5A RS00340
gene id: 1642646:ING2E5A_RS00340
uniprot id: A0A1G4G310
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS09035
gene id: 1642646:ING2E5A_RS09035
uniprot id: A0A1G4G863
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1642646:ING2E5A RS10575
gene id: 1642646:ING2E5A_RS10575
uniprot id: A0A1G4G8Z2
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1642646:ING2E5A RS04890
gene id: 1642646:ING2E5A_RS04890
uniprot id: A0A1G4G5T1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1642646:ING2E5A RS06755
gene id: 1642646:ING2E5A_RS06755
uniprot id: A0A1G4G6W2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1642646:ING2E5A RS11835
gene id: 1642646:ING2E5A_RS11835
uniprot id: A0A1G4G9T0
names: Similarity
messages: Belongs to the peptidase S8 family.

1642646:ING2E5A RS06825
gene id: 1642646:ING2E5A_RS06825
uniprot id: A0A1G4G6S7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1642646:ING2E5A RS08405
gene id: 1642646:ING2E5A_RS08405
uniprot id: A0A1G4G7P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1642646:ING2E5A RS14900
gene id: 1642646:ING2E5A_RS14900
uniprot id: A0A1G4GBG0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS04340
gene id: 1642646:ING2E5A_RS04340
uniprot id: A0A1G4G5C8
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1642646:ING2E5A RS03180
gene id: 1642646:ING2E5A_RS03180
uniprot id: A0A1G4G4M1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1642646:ING2E5A RS14130
gene id: 1642646:ING2E5A_RS14130
uniprot id: A0A1G4GB12
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS12305
gene id: 1642646:ING2E5A_RS12305
uniprot id: A0A1G4GA01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS07200
gene id: 1642646:ING2E5A_RS07200
uniprot id: A0A1G4G727
names: Similarity
messages: Belongs to the MreC family.

1642646:ING2E5A RS03560
gene id: 1642646:ING2E5A_RS03560
uniprot id: A0A1G4G4W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1642646:ING2E5A RS05830
gene id: 1642646:ING2E5A_RS05830
uniprot id: A0A1G4G6H6
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1642646:ING2E5A RS01525
gene id: 1642646:ING2E5A_RS01525
uniprot id: A0A1G4G3R5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1642646:ING2E5A RS09930
gene id: 1642646:ING2E5A_RS09930
uniprot id: A0A1G4G8J0
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS00105
gene id: 1642646:ING2E5A_RS00105
uniprot id: A0A1G4G378
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1642646:ING2E5A RS11225
gene id: 1642646:ING2E5A_RS11225
uniprot id: A0A1G4G9A0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1642646:ING2E5A RS05650
gene id: 1642646:ING2E5A_RS05650
uniprot id: A0A1G4G652
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1642646:ING2E5A RS02850
gene id: 1642646:ING2E5A_RS02850
uniprot id: A0A1G4G4K9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1642646:ING2E5A RS14250
gene id: 1642646:ING2E5A_RS14250
uniprot id: A0A1G4GB16
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1642646:ING2E5A RS02145
gene id: 1642646:ING2E5A_RS02145
uniprot id: A0A1G4G451
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1642646:ING2E5A RS05310
gene id: 1642646:ING2E5A_RS05310
uniprot id: A0A1G4G5Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

1642646:ING2E5A RS08305
gene id: 1642646:ING2E5A_RS08305
uniprot id: A0A1G4G7T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1642646:ING2E5A RS05435
gene id: 1642646:ING2E5A_RS05435
uniprot id: A0A1G4G6A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS12770
gene id: 1642646:ING2E5A_RS12770
uniprot id: A0A1G4GA75
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS12445
gene id: 1642646:ING2E5A_RS12445
uniprot id: A0A1G4G9Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1642646:ING2E5A RS10265
gene id: 1642646:ING2E5A_RS10265
uniprot id: A0A1G4G8T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1642646:ING2E5A RS07530
gene id: 1642646:ING2E5A_RS07530
uniprot id: A0A1G4G776
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1642646:ING2E5A RS12370
gene id: 1642646:ING2E5A_RS12370
uniprot id: A0A1G4GA37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS06010
gene id: 1642646:ING2E5A_RS06010
uniprot id: A0A1G4G6B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1642646:ING2E5A RS14770
gene id: 1642646:ING2E5A_RS14770
uniprot id: A0A1G4GBB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1642646:ING2E5A RS01840
gene id: 1642646:ING2E5A_RS01840
uniprot id: A0A1G4G3X7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS13535
gene id: 1642646:ING2E5A_RS13535
uniprot id: A0A1G4GAN1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1642646:ING2E5A RS06425
gene id: 1642646:ING2E5A_RS06425
uniprot id: A0A1G4G6K4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS14760
gene id: 1642646:ING2E5A_RS14760
uniprot id: A0A1G4GBF6
names: Similarity
messages: Belongs to the ComB family.

1642646:ING2E5A RS06165
gene id: 1642646:ING2E5A_RS06165
uniprot id: A0A1G4G6F0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1642646:ING2E5A RS03400
gene id: 1642646:ING2E5A_RS03400
uniprot id: A0A1G4G508
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1642646:ING2E5A RS14170
gene id: 1642646:ING2E5A_RS14170
uniprot id: A0A1G4GB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1642646:ING2E5A RS12450
gene id: 1642646:ING2E5A_RS12450
uniprot id: A0A1G4GA69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1642646:ING2E5A RS12175
gene id: 1642646:ING2E5A_RS12175
uniprot id: A0A1G4G9Z7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1642646:ING2E5A RS14810
gene id: 1642646:ING2E5A_RS14810
uniprot id: A0A1G4GBG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1642646:ING2E5A RS12830
gene id: 1642646:ING2E5A_RS12830
uniprot id: A0A1G4GAC9
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS00960
gene id: 1642646:ING2E5A_RS00960
uniprot id: A0A1G4G3C3
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS06760
gene id: 1642646:ING2E5A_RS06760
uniprot id: A0A1G4G6U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1642646:ING2E5A RS03015
gene id: 1642646:ING2E5A_RS03015
uniprot id: A0A1G4G4R6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1642646:ING2E5A RS03325
gene id: 1642646:ING2E5A_RS03325
uniprot id: A0A1G4G4V8
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1642646:ING2E5A RS12940
gene id: 1642646:ING2E5A_RS12940
uniprot id: A0A1G4GA95
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1642646:ING2E5A RS00170
gene id: 1642646:ING2E5A_RS00170
uniprot id: A0A1G4G2X6
names: Similarity
messages: Belongs to the thioredoxin family.

1642646:ING2E5A RS01210
gene id: 1642646:ING2E5A_RS01210
uniprot id: A0A1G4G3T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1642646:ING2E5A RS09520
gene id: 1642646:ING2E5A_RS09520
uniprot id: A0A1G4G8E0
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS08680
gene id: 1642646:ING2E5A_RS08680
uniprot id: A0A1G4G7W2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1642646:ING2E5A RS09110
gene id: 1642646:ING2E5A_RS09110
uniprot id: A0A1G4G852
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS02620
gene id: 1642646:ING2E5A_RS02620
uniprot id: A0A1G4G4L3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1642646:ING2E5A RS09555
gene id: 1642646:ING2E5A_RS09555
uniprot id: A0A1G4G8H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1642646:ING2E5A RS12905
gene id: 1642646:ING2E5A_RS12905
uniprot id: A0A1G4GA97
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1642646:ING2E5A RS11680
gene id: 1642646:ING2E5A_RS11680
uniprot id: A0A1G4G9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1642646:ING2E5A RS07360
gene id: 1642646:ING2E5A_RS07360
uniprot id: A0A1G4G754
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS13110
gene id: 1642646:ING2E5A_RS13110
uniprot id: A0A1G4GAJ9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1642646:ING2E5A RS12725
gene id: 1642646:ING2E5A_RS12725
uniprot id: A0A1G4GA89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1642646:ING2E5A RS14295
gene id: 1642646:ING2E5A_RS14295
uniprot id: A0A1G4GB76
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1642646:ING2E5A RS10095
gene id: 1642646:ING2E5A_RS10095
uniprot id: A0A1G4G8Q0
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1642646:ING2E5A RS01990
gene id: 1642646:ING2E5A_RS01990
uniprot id: A0A1G4G413
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS11810
gene id: 1642646:ING2E5A_RS11810
uniprot id: A0A1G4G9L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS04955
gene id: 1642646:ING2E5A_RS04955
uniprot id: A0A1G4G5Q4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS07790
gene id: 1642646:ING2E5A_RS07790
uniprot id: A0A1G4G7E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1642646:ING2E5A RS08445
gene id: 1642646:ING2E5A_RS08445
uniprot id: A0A1G4G7T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1642646:ING2E5A RS14610
gene id: 1642646:ING2E5A_RS14610
uniprot id: A0A1G4GBC3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1642646:ING2E5A RS05815
gene id: 1642646:ING2E5A_RS05815
uniprot id: A0A1G4G680
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1642646:ING2E5A RS06240
gene id: 1642646:ING2E5A_RS06240
uniprot id: A0A1G4G6H3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1642646:ING2E5A RS07160
gene id: 1642646:ING2E5A_RS07160
uniprot id: A0A1G4G708
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1642646:ING2E5A RS13155
gene id: 1642646:ING2E5A_RS13155
uniprot id: A0A1G4GAD9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1642646:ING2E5A RS08480
gene id: 1642646:ING2E5A_RS08480
uniprot id: A0A1G4G7S1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1642646:ING2E5A RS13140
gene id: 1642646:ING2E5A_RS13140
uniprot id: A0A1G4GAK8
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

1642646:ING2E5A RS04315
gene id: 1642646:ING2E5A_RS04315
uniprot id: A0A1G4G5B6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1642646:ING2E5A RS12160
gene id: 1642646:ING2E5A_RS12160
uniprot id: A0A1G4G9X2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1642646:ING2E5A RS07040
gene id: 1642646:ING2E5A_RS07040
uniprot id: A0A1G4G6X6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1642646:ING2E5A RS03975
gene id: 1642646:ING2E5A_RS03975
uniprot id: A0A1G4G5A4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1642646:ING2E5A RS01410
gene id: 1642646:ING2E5A_RS01410
uniprot id: A0A1G4G3S5
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS05320
gene id: 1642646:ING2E5A_RS05320
uniprot id: A0A1G4G5Y3
names: Similarity
messages: Belongs to the citrate synthase family.

1642646:ING2E5A RS05095
gene id: 1642646:ING2E5A_RS05095
uniprot id: A0A1G4G5U6
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1642646:ING2E5A RS14095
gene id: 1642646:ING2E5A_RS14095
uniprot id: A0A1G4GB18
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS02500
gene id: 1642646:ING2E5A_RS02500
uniprot id: A0A1G4G488
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1642646:ING2E5A RS04520
gene id: 1642646:ING2E5A_RS04520
uniprot id: A0A1G4G5H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1642646:ING2E5A RS07065
gene id: 1642646:ING2E5A_RS07065
uniprot id: A0A1G4G6Y8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1642646:ING2E5A RS12635
gene id: 1642646:ING2E5A_RS12635
uniprot id: A0A1G4GA93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1642646:ING2E5A RS09590
gene id: 1642646:ING2E5A_RS09590
uniprot id: A0A1G4G8J2
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1642646:ING2E5A RS08265
gene id: 1642646:ING2E5A_RS08265
uniprot id: A0A1G4G7N2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1642646:ING2E5A RS02590
gene id: 1642646:ING2E5A_RS02590
uniprot id: A0A1G4G4G1
names: Similarity
messages: Belongs to the peptidase S51 family.

1642646:ING2E5A RS04900
gene id: 1642646:ING2E5A_RS04900
uniprot id: A0A1G4G5Q3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS04880
gene id: 1642646:ING2E5A_RS04880
uniprot id: A0A1G4G5Y4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1642646:ING2E5A RS13565
gene id: 1642646:ING2E5A_RS13565
uniprot id: A0A1G4GAQ8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1642646:ING2E5A RS11630
gene id: 1642646:ING2E5A_RS11630
uniprot id: A0A1G4G9J3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1642646:ING2E5A RS03105
gene id: 1642646:ING2E5A_RS03105
uniprot id: A0A1G4G4M5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1642646:ING2E5A RS06430
gene id: 1642646:ING2E5A_RS06430
uniprot id: A0A1G4G6N5
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1642646:ING2E5A RS08435
gene id: 1642646:ING2E5A_RS08435
uniprot id: A0A1G4G7S8
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1642646:ING2E5A RS10660
gene id: 1642646:ING2E5A_RS10660
uniprot id: A0A1G4G8Z8
names: Similarity
messages: Belongs to the peptidase S66 family.

1642646:ING2E5A RS11710
gene id: 1642646:ING2E5A_RS11710
uniprot id: A0A1G4G9Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1642646:ING2E5A RS12925
gene id: 1642646:ING2E5A_RS12925
uniprot id: A0A1G4GAD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1642646:ING2E5A RS03300
gene id: 1642646:ING2E5A_RS03300
uniprot id: A0A1G4G4W6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1642646:ING2E5A RS06535
gene id: 1642646:ING2E5A_RS06535
uniprot id: A0A1G4G6S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS01995
gene id: 1642646:ING2E5A_RS01995
uniprot id: A0A1G4G3Z3
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS13475
gene id: 1642646:ING2E5A_RS13475
uniprot id: A0A1G4GAM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1642646:ING2E5A RS07195
gene id: 1642646:ING2E5A_RS07195
uniprot id: A0A1G4G761
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1642646:ING2E5A RS05795
gene id: 1642646:ING2E5A_RS05795
uniprot id: A0A1G4G6C0
names: Similarity
messages: Belongs to the peptidase S13 family.

1642646:ING2E5A RS00120
gene id: 1642646:ING2E5A_RS00120
uniprot id: A0A1G4G356
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS03670
gene id: 1642646:ING2E5A_RS03670
uniprot id: A0A1G4G542
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1642646:ING2E5A RS11525
gene id: 1642646:ING2E5A_RS11525
uniprot id: A0A1G4G9J2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS03715
gene id: 1642646:ING2E5A_RS03715
uniprot id: A0A1G4G4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS03410
gene id: 1642646:ING2E5A_RS03410
uniprot id: A0A1G4G4W3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1642646:ING2E5A RS07010
gene id: 1642646:ING2E5A_RS07010
uniprot id: A0A1G4G715
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1642646:ING2E5A RS03545
gene id: 1642646:ING2E5A_RS03545
uniprot id: A0A1G4G529
names: Similarity
messages: Belongs to the ParB family.

1642646:ING2E5A RS11750
gene id: 1642646:ING2E5A_RS11750
uniprot id: A0A1G4G9R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1642646:ING2E5A RS14245
gene id: 1642646:ING2E5A_RS14245
uniprot id: A0A1G4GB67
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS06590
gene id: 1642646:ING2E5A_RS06590
uniprot id: A0A1G4G6Q7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1642646:ING2E5A RS11285
gene id: 1642646:ING2E5A_RS11285
uniprot id: A0A1G4G9G5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1642646:ING2E5A RS03370
gene id: 1642646:ING2E5A_RS03370
uniprot id: A0A1G4G4R8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1642646:ING2E5A RS08650
gene id: 1642646:ING2E5A_RS08650
uniprot id: A0A1G4G801
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1642646:ING2E5A RS13400
gene id: 1642646:ING2E5A_RS13400
uniprot id: A0A1G4GAJ1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1642646:ING2E5A RS13250
gene id: 1642646:ING2E5A_RS13250
uniprot id: A0A1G4GAN0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1642646:ING2E5A RS00190
gene id: 1642646:ING2E5A_RS00190
uniprot id: A0A1G4G2Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1642646:ING2E5A RS08875
gene id: 1642646:ING2E5A_RS08875
uniprot id: A0A1G4G807
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1642646:ING2E5A RS00560
gene id: 1642646:ING2E5A_RS00560
uniprot id: A0A1G4G3F8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1642646:ING2E5A RS00635
gene id: 1642646:ING2E5A_RS00635
uniprot id: A0A1G4G391
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1642646:ING2E5A RS10065
gene id: 1642646:ING2E5A_RS10065
uniprot id: A0A1G4G8Q9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1642646:ING2E5A RS07795
gene id: 1642646:ING2E5A_RS07795
uniprot id: A0A1G4G7C7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1642646:ING2E5A RS13410
gene id: 1642646:ING2E5A_RS13410
uniprot id: A0A1G4GAJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1642646:ING2E5A RS05695
gene id: 1642646:ING2E5A_RS05695
uniprot id: A0A1G4G661
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1642646:ING2E5A RS02125
gene id: 1642646:ING2E5A_RS02125
uniprot id: A0A1G4G4B1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS12825
gene id: 1642646:ING2E5A_RS12825
uniprot id: A0A1G4GAB1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1642646:ING2E5A RS08555
gene id: 1642646:ING2E5A_RS08555
uniprot id: A0A1G4G7S2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1642646:ING2E5A RS08785
gene id: 1642646:ING2E5A_RS08785
uniprot id: A0A1G4G808
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS02585
gene id: 1642646:ING2E5A_RS02585
uniprot id: A0A1G4G4A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1642646:ING2E5A RS01190
gene id: 1642646:ING2E5A_RS01190
uniprot id: A0A1G4G3H8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1642646:ING2E5A RS01725
gene id: 1642646:ING2E5A_RS01725
uniprot id: A0A1G4G3W1
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1642646:ING2E5A RS00255
gene id: 1642646:ING2E5A_RS00255
uniprot id: A0A1G4G335
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1642646:ING2E5A RS11345
gene id: 1642646:ING2E5A_RS11345
uniprot id: A0A1G4G9I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1642646:ING2E5A RS12200
gene id: 1642646:ING2E5A_RS12200
uniprot id: A0A1G4GA13
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS01715
gene id: 1642646:ING2E5A_RS01715
uniprot id: A0A1G4G431
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS05680
gene id: 1642646:ING2E5A_RS05680
uniprot id: A0A1G4G650
names: Similarity
messages: Belongs to the stealth family.

1642646:ING2E5A RS08740
gene id: 1642646:ING2E5A_RS08740
uniprot id: A0A1G4G7X5
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS07220
gene id: 1642646:ING2E5A_RS07220
uniprot id: A0A1G4G711
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1642646:ING2E5A RS05905
gene id: 1642646:ING2E5A_RS05905
uniprot id: A0A1G4G6E5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-552 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Binds 5 heme c groups covalently per monomer.
messages: Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
messages: Periplasm

1642646:ING2E5A RS06235
gene id: 1642646:ING2E5A_RS06235
uniprot id: A0A1G4G6L5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1642646:ING2E5A RS12165
gene id: 1642646:ING2E5A_RS12165
uniprot id: A0A1G4G9U8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS03775
gene id: 1642646:ING2E5A_RS03775
uniprot id: A0A1G4G563
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1642646:ING2E5A RS14370
gene id: 1642646:ING2E5A_RS14370
uniprot id: A0A1G4GB66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1642646:ING2E5A RS11250
gene id: 1642646:ING2E5A_RS11250
uniprot id: A0A1G4G9G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1642646:ING2E5A RS00125
gene id: 1642646:ING2E5A_RS00125
uniprot id: A0A1G4G2X1
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS11775
gene id: 1642646:ING2E5A_RS11775
uniprot id: A0A1G4G9M0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1642646:ING2E5A RS11755
gene id: 1642646:ING2E5A_RS11755
uniprot id: A0A1G4G9L1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1642646:ING2E5A RS05260
gene id: 1642646:ING2E5A_RS05260
uniprot id: A0A1G4G5Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1642646:ING2E5A RS14405
gene id: 1642646:ING2E5A_RS14405
uniprot id: A0A1G4GB47
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1642646:ING2E5A RS14655
gene id: 1642646:ING2E5A_RS14655
uniprot id: A0A1G4GBC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1642646:ING2E5A RS07035
gene id: 1642646:ING2E5A_RS07035
uniprot id: A0A1G4G6Z9
names: Similarity
messages: Belongs to the UPF0145 family.

1642646:ING2E5A RS04575
gene id: 1642646:ING2E5A_RS04575
uniprot id: A0A1G4G5H9
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1642646:ING2E5A RS10610
gene id: 1642646:ING2E5A_RS10610
uniprot id: A0A1G4G8Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1642646:ING2E5A RS08135
gene id: 1642646:ING2E5A_RS08135
uniprot id: A0A1G4G7L1
names: Similarity
messages: Belongs to the CinA family.

1642646:ING2E5A RS06190
gene id: 1642646:ING2E5A_RS06190
uniprot id: A0A1G4G6K9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1642646:ING2E5A RS04080
gene id: 1642646:ING2E5A_RS04080
uniprot id: A0A1G4G5B1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1642646:ING2E5A RS12470
gene id: 1642646:ING2E5A_RS12470
uniprot id: A0A1G4GA62
names: Similarity
messages: Belongs to the arginine deiminase family.

1642646:ING2E5A RS10025
gene id: 1642646:ING2E5A_RS10025
uniprot id: A0A1G4G8N0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS13150
gene id: 1642646:ING2E5A_RS13150
uniprot id: A0A1G4GAF0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1642646:ING2E5A RS00555
gene id: 1642646:ING2E5A_RS00555
uniprot id: A0A1G4G3A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1642646:ING2E5A RS12920
gene id: 1642646:ING2E5A_RS12920
uniprot id: A0A1G4GAA2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS14825
gene id: 1642646:ING2E5A_RS14825
uniprot id: A0A1G4GBK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1642646:ING2E5A RS08095
gene id: 1642646:ING2E5A_RS08095
uniprot id: A0A1G4G7L9
names: Similarity
messages: Belongs to the AIR synthase family.

1642646:ING2E5A RS05715
gene id: 1642646:ING2E5A_RS05715
uniprot id: A0A1G4G663
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1642646:ING2E5A RS14895
gene id: 1642646:ING2E5A_RS14895
uniprot id: A0A1G4GBF2
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS06620
gene id: 1642646:ING2E5A_RS06620
uniprot id: A0A1G4G6N7
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

1642646:ING2E5A RS03295
gene id: 1642646:ING2E5A_RS03295
uniprot id: A0A1G4G4Q1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1642646:ING2E5A RS05245
gene id: 1642646:ING2E5A_RS05245
uniprot id: A0A1G4G5X3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1642646:ING2E5A RS11955
gene id: 1642646:ING2E5A_RS11955
uniprot id: A0A1G4G9R0
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS11145
gene id: 1642646:ING2E5A_RS11145
uniprot id: A0A1G4G9D9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1642646:ING2E5A RS11785
gene id: 1642646:ING2E5A_RS11785
uniprot id: A0A1G4G9R4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1642646:ING2E5A RS14140
gene id: 1642646:ING2E5A_RS14140
uniprot id: A0A1G4GAZ8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1642646:ING2E5A RS07060
gene id: 1642646:ING2E5A_RS07060
uniprot id: A0A1G4G704
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS04160
gene id: 1642646:ING2E5A_RS04160
uniprot id: A0A1G4G5F8
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1642646:ING2E5A RS09570
gene id: 1642646:ING2E5A_RS09570
uniprot id: A0A1G4G8E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1642646:ING2E5A RS06585
gene id: 1642646:ING2E5A_RS06585
uniprot id: A0A1G4G6N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1642646:ING2E5A RS05370
gene id: 1642646:ING2E5A_RS05370
uniprot id: A0A1G4G5Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1642646:ING2E5A RS04035
gene id: 1642646:ING2E5A_RS04035
uniprot id: A0A1G4G599
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1642646:ING2E5A RS01315
gene id: 1642646:ING2E5A_RS01315
uniprot id: A0A1G4G3K4
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS01360
gene id: 1642646:ING2E5A_RS01360
uniprot id: A0A1G4G3W9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1642646:ING2E5A RS03745
gene id: 1642646:ING2E5A_RS03745
uniprot id: A0A1G4G4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS04370
gene id: 1642646:ING2E5A_RS04370
uniprot id: A0A1G4G5G9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS05485
gene id: 1642646:ING2E5A_RS05485
uniprot id: A0A1G4G610
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1642646:ING2E5A RS00620
gene id: 1642646:ING2E5A_RS00620
uniprot id: A0A1G4G368
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

1642646:ING2E5A RS05255
gene id: 1642646:ING2E5A_RS05255
uniprot id: A0A1G4G5W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1642646:ING2E5A RS01215
gene id: 1642646:ING2E5A_RS01215
uniprot id: A0A1G4G3I1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1642646:ING2E5A RS08625
gene id: 1642646:ING2E5A_RS08625
uniprot id: A0A1G4G7U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS07165
gene id: 1642646:ING2E5A_RS07165
uniprot id: A0A1G4G703
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1642646:ING2E5A RS02185
gene id: 1642646:ING2E5A_RS02185
uniprot id: A0A1G4G446
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1642646:ING2E5A RS12090
gene id: 1642646:ING2E5A_RS12090
uniprot id: A0A1G4G9Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1642646:ING2E5A RS06270
gene id: 1642646:ING2E5A_RS06270
uniprot id: A0A1G4G6Q2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS06780
gene id: 1642646:ING2E5A_RS06780
uniprot id: A0A1G4G6V3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS11295
gene id: 1642646:ING2E5A_RS11295
uniprot id: A0A1G4G9C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1642646:ING2E5A RS01580
gene id: 1642646:ING2E5A_RS01580
uniprot id: A0A1G4G3S0
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS12170
gene id: 1642646:ING2E5A_RS12170
uniprot id: A0A1G4G9U7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1642646:ING2E5A RS02400
gene id: 1642646:ING2E5A_RS02400
uniprot id: A0A1G4G464
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS13090
gene id: 1642646:ING2E5A_RS13090
uniprot id: A0A1G4GAJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS07045
gene id: 1642646:ING2E5A_RS07045
uniprot id: A0A1G4G6Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1642646:ING2E5A RS12900
gene id: 1642646:ING2E5A_RS12900
uniprot id: A0A1G4GAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1642646:ING2E5A RS05115
gene id: 1642646:ING2E5A_RS05115
uniprot id: A0A1G4G5U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1642646:ING2E5A RS00110
gene id: 1642646:ING2E5A_RS00110
uniprot id: A0A1G4G2W7
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1642646:ING2E5A RS09080
gene id: 1642646:ING2E5A_RS09080
uniprot id: A0A1G4G848
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS08400
gene id: 1642646:ING2E5A_RS08400
uniprot id: A0A1G4G7V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1642646:ING2E5A RS05105
gene id: 1642646:ING2E5A_RS05105
uniprot id: A0A1G4G5T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1642646:ING2E5A RS03555
gene id: 1642646:ING2E5A_RS03555
uniprot id: A0A1G4G4Z6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1642646:ING2E5A RS05305
gene id: 1642646:ING2E5A_RS05305
uniprot id: A0A1G4G5W6
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS01935
gene id: 1642646:ING2E5A_RS01935
uniprot id: A0A1G4G3Z6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1642646:ING2E5A RS00030
gene id: 1642646:ING2E5A_RS00030
uniprot id: A0A1G4G2X5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1642646:ING2E5A RS13885
gene id: 1642646:ING2E5A_RS13885
uniprot id: A0A1G4GAU8
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1642646:ING2E5A RS12465
gene id: 1642646:ING2E5A_RS12465
uniprot id: A0A1G4GA06
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1642646:ING2E5A RS09650
gene id: 1642646:ING2E5A_RS09650
uniprot id: A0A1G4G8K5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1642646:ING2E5A RS01560
gene id: 1642646:ING2E5A_RS01560
uniprot id: A0A1G4G3V4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1642646:ING2E5A RS09665
gene id: 1642646:ING2E5A_RS09665
uniprot id: A0A1G4G8G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1642646:ING2E5A RS07760
gene id: 1642646:ING2E5A_RS07760
uniprot id: A0A1G4G7C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1642646:ING2E5A RS07105
gene id: 1642646:ING2E5A_RS07105
uniprot id: A0A1G4G706
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1642646:ING2E5A RS07205
gene id: 1642646:ING2E5A_RS07205
uniprot id: A0A1G4G734
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1642646:ING2E5A RS11915
gene id: 1642646:ING2E5A_RS11915
uniprot id: A0A1G4G9V2
names: Similarity
messages: Belongs to the DprA/Smf family.

1642646:ING2E5A RS14840
gene id: 1642646:ING2E5A_RS14840
uniprot id: A0A1G4GBJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1642646:ING2E5A RS07480
gene id: 1642646:ING2E5A_RS07480
uniprot id: A0A1G4G770
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1642646:ING2E5A RS01160
gene id: 1642646:ING2E5A_RS01160
uniprot id: A0A1G4G3T1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1642646:ING2E5A RS05200
gene id: 1642646:ING2E5A_RS05200
uniprot id: A0A1G4G604
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1642646:ING2E5A RS07650
gene id: 1642646:ING2E5A_RS07650
uniprot id: A0A1G4G7G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1642646:ING2E5A RS00130
gene id: 1642646:ING2E5A_RS00130
uniprot id: A0A1G4G2W8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1642646:ING2E5A RS10680
gene id: 1642646:ING2E5A_RS10680
uniprot id: A0A1G4G920
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1642646:ING2E5A RS02075
gene id: 1642646:ING2E5A_RS02075
uniprot id: A0A1G4G411
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1642646:ING2E5A RS02955
gene id: 1642646:ING2E5A_RS02955
uniprot id: A0A1G4G4I9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS00145
gene id: 1642646:ING2E5A_RS00145
uniprot id: A0A1G4G2X2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1642646:ING2E5A RS06300
gene id: 1642646:ING2E5A_RS06300
uniprot id: A0A1G4G6H8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1642646:ING2E5A RS09865
gene id: 1642646:ING2E5A_RS09865
uniprot id: A0A1G4G8J5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1642646:ING2E5A RS14670
gene id: 1642646:ING2E5A_RS14670
uniprot id: A0A1G4GBA0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1642646:ING2E5A RS09680
gene id: 1642646:ING2E5A_RS09680
uniprot id: A0A1G4G8F1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1642646:ING2E5A RS07415
gene id: 1642646:ING2E5A_RS07415
uniprot id: A0A1G4G753
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1642646:ING2E5A RS12775
gene id: 1642646:ING2E5A_RS12775
uniprot id: A0A1G4GA98
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1642646:ING2E5A RS09900
gene id: 1642646:ING2E5A_RS09900
uniprot id: A0A1G4G8Q6
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS11280
gene id: 1642646:ING2E5A_RS11280
uniprot id: A0A1G4G9E6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1642646:ING2E5A RS01165
gene id: 1642646:ING2E5A_RS01165
uniprot id: A0A1G4G3H1
names: Similarity
messages: Belongs to the fructosamine kinase family.

1642646:ING2E5A RS10165
gene id: 1642646:ING2E5A_RS10165
uniprot id: A0A1G4G8N7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1642646:ING2E5A RS05045
gene id: 1642646:ING2E5A_RS05045
uniprot id: A0A1G4G5T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1642646:ING2E5A RS08720
gene id: 1642646:ING2E5A_RS08720
uniprot id: A0A1G4G7Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1642646:ING2E5A RS14675
gene id: 1642646:ING2E5A_RS14675
uniprot id: A0A1G4GBH8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1642646:ING2E5A RS04515
gene id: 1642646:ING2E5A_RS04515
uniprot id: A0A1G4G5G6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1642646:ING2E5A RS04600
gene id: 1642646:ING2E5A_RS04600
uniprot id: A0A1G4G5J5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1642646:ING2E5A RS03005
gene id: 1642646:ING2E5A_RS03005
uniprot id: A0A1G4G4K0
names: Similarity
messages: Belongs to the peptidase M16 family.

1642646:ING2E5A RS11435
gene id: 1642646:ING2E5A_RS11435
uniprot id: A0A1G4G9E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1642646:ING2E5A RS01240
gene id: 1642646:ING2E5A_RS01240
uniprot id: A0A1G4G3I9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1642646:ING2E5A RS12780
gene id: 1642646:ING2E5A_RS12780
uniprot id: A0A1G4GAB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1642646:ING2E5A RS05430
gene id: 1642646:ING2E5A_RS05430
uniprot id: A0A1G4G602
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1642646:ING2E5A RS08960
gene id: 1642646:ING2E5A_RS08960
uniprot id: A0A1G4G804
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1642646:ING2E5A RS13545
gene id: 1642646:ING2E5A_RS13545
uniprot id: A0A1G4GAM4
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

1642646:ING2E5A RS02640
gene id: 1642646:ING2E5A_RS02640
uniprot id: A0A1G4G4D8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1642646:ING2E5A RS07390
gene id: 1642646:ING2E5A_RS07390
uniprot id: A0A1G4G749
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1642646:ING2E5A RS03570
gene id: 1642646:ING2E5A_RS03570
uniprot id: A0A1G4G4W7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1642646:ING2E5A RS09505
gene id: 1642646:ING2E5A_RS09505
uniprot id: A0A1G4G8B5
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS04925
gene id: 1642646:ING2E5A_RS04925
uniprot id: A0A1G4G5N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1642646:ING2E5A RS08285
gene id: 1642646:ING2E5A_RS08285
uniprot id: A0A1G4G7M6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1642646:ING2E5A RS11430
gene id: 1642646:ING2E5A_RS11430
uniprot id: A0A1G4G9K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1642646:ING2E5A RS03195
gene id: 1642646:ING2E5A_RS03195
uniprot id: A0A1G4G4T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1642646:ING2E5A RS03305
gene id: 1642646:ING2E5A_RS03305
uniprot id: A0A1G4G4Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1642646:ING2E5A RS04195
gene id: 1642646:ING2E5A_RS04195
uniprot id: A0A1G4G5E6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1642646:ING2E5A RS11675
gene id: 1642646:ING2E5A_RS11675
uniprot id: A0A1G4G9Q9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1642646:ING2E5A RS09630
gene id: 1642646:ING2E5A_RS09630
uniprot id: A0A1G4G8F8
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS14775
gene id: 1642646:ING2E5A_RS14775
uniprot id: A0A1G4GBJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1642646:ING2E5A RS11720
gene id: 1642646:ING2E5A_RS11720
uniprot id: A0A1G4G9N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1642646:ING2E5A RS13100
gene id: 1642646:ING2E5A_RS13100
uniprot id: A0A1G4GAE1
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1642646:ING2E5A RS01925
gene id: 1642646:ING2E5A_RS01925
uniprot id: A0A1G4G3X5
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS11480
gene id: 1642646:ING2E5A_RS11480
uniprot id: A0A1G4G9L4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1642646:ING2E5A RS11350
gene id: 1642646:ING2E5A_RS11350
uniprot id: A0A1G4G9H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1642646:ING2E5A RS13875
gene id: 1642646:ING2E5A_RS13875
uniprot id: A0A1G4GAU5
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS13600
gene id: 1642646:ING2E5A_RS13600
uniprot id: A0A1G4GAN2
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS02305
gene id: 1642646:ING2E5A_RS02305
uniprot id: A0A1G4G4C6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1642646:ING2E5A RS11290
gene id: 1642646:ING2E5A_RS11290
uniprot id: A0A1G4G9C1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1642646:ING2E5A RS06640
gene id: 1642646:ING2E5A_RS06640
uniprot id: A0A1G4G6P0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1642646:ING2E5A RS04375
gene id: 1642646:ING2E5A_RS04375
uniprot id: A0A1G4G5E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS08175
gene id: 1642646:ING2E5A_RS08175
uniprot id: A0A1G4G7K8
names: Similarity
messages: Belongs to the CapA family.

1642646:ING2E5A RS05840
gene id: 1642646:ING2E5A_RS05840
uniprot id: A0A1G4G6D3
names: Similarity
messages: Belongs to the peptidase C69 family.

1642646:ING2E5A RS14385
gene id: 1642646:ING2E5A_RS14385
uniprot id: A0A1G4GB43
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1642646:ING2E5A RS12395
gene id: 1642646:ING2E5A_RS12395
uniprot id: A0A1G4G9Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1642646:ING2E5A RS08090
gene id: 1642646:ING2E5A_RS08090
uniprot id: A0A1G4G7I3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1642646:ING2E5A RS06725
gene id: 1642646:ING2E5A_RS06725
uniprot id: A0A1G4G6Q3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1642646:ING2E5A RS11330
gene id: 1642646:ING2E5A_RS11330
uniprot id: A0A1G4G9H7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1642646:ING2E5A RS01270
gene id: 1642646:ING2E5A_RS01270
uniprot id: A0A1G4G3M0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1642646:ING2E5A RS02415
gene id: 1642646:ING2E5A_RS02415
uniprot id: A0A1G4G4E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1642646:ING2E5A RS06635
gene id: 1642646:ING2E5A_RS06635
uniprot id: A0A1G4G6W4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1642646:ING2E5A RS02360
gene id: 1642646:ING2E5A_RS02360
uniprot id: A0A1G4G465
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1642646:ING2E5A RS10040
gene id: 1642646:ING2E5A_RS10040
uniprot id: A0A1G4G8Q1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1642646:ING2E5A RS11545
gene id: 1642646:ING2E5A_RS11545
uniprot id: A0A1G4G9K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1642646:ING2E5A RS03520
gene id: 1642646:ING2E5A_RS03520
uniprot id: A0A1G4G4V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1642646:ING2E5A RS07675
gene id: 1642646:ING2E5A_RS07675
uniprot id: A0A1G4G7A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1642646:ING2E5A RS14715
gene id: 1642646:ING2E5A_RS14715
uniprot id: A0A1G4GBE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1642646:ING2E5A RS00940
gene id: 1642646:ING2E5A_RS00940
uniprot id: A0A1G4G3E2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1642646:ING2E5A RS07425
gene id: 1642646:ING2E5A_RS07425
uniprot id: A0A1G4G751
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1642646:ING2E5A RS07670
gene id: 1642646:ING2E5A_RS07670
uniprot id: A0A1G4G7E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1642646:ING2E5A RS02430
gene id: 1642646:ING2E5A_RS02430
uniprot id: A0A1G4G4A6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS13060
gene id: 1642646:ING2E5A_RS13060
uniprot id: A0A1G4GAI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1642646:ING2E5A RS06115
gene id: 1642646:ING2E5A_RS06115
uniprot id: A0A1G4G6D7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1642646:ING2E5A RS08260
gene id: 1642646:ING2E5A_RS08260
uniprot id: A0A1G4G7L7
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

1642646:ING2E5A RS12345
gene id: 1642646:ING2E5A_RS12345
uniprot id: A0A1G4G9X4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS13615
gene id: 1642646:ING2E5A_RS13615
uniprot id: A0A1G4GAS5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1642646:ING2E5A RS13580
gene id: 1642646:ING2E5A_RS13580
uniprot id: A0A1G4GAN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1642646:ING2E5A RS08660
gene id: 1642646:ING2E5A_RS08660
uniprot id: A0A1G4G7W0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1642646:ING2E5A RS03495
gene id: 1642646:ING2E5A_RS03495
uniprot id: A0A1G4G524
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1642646:ING2E5A RS06380
gene id: 1642646:ING2E5A_RS06380
uniprot id: A0A1G4G6M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1642646:ING2E5A RS03135
gene id: 1642646:ING2E5A_RS03135
uniprot id: A0A1G4G4L4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS06145
gene id: 1642646:ING2E5A_RS06145
uniprot id: A0A1G4G6D9
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1642646:ING2E5A RS11795
gene id: 1642646:ING2E5A_RS11795
uniprot id: A0A1G4G9Q1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1642646:ING2E5A RS08200
gene id: 1642646:ING2E5A_RS08200
uniprot id: A0A1G4G7R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1642646:ING2E5A RS02310
gene id: 1642646:ING2E5A_RS02310
uniprot id: A0A1G4G454
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1642646:ING2E5A RS09130
gene id: 1642646:ING2E5A_RS09130
uniprot id: A0A1G4G855
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1642646:ING2E5A RS05020
gene id: 1642646:ING2E5A_RS05020
uniprot id: A0A1G4G5R0
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1642646:ING2E5A RS10080
gene id: 1642646:ING2E5A_RS10080
uniprot id: A0A1G4G8N6
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1642646:ING2E5A RS06285
gene id: 1642646:ING2E5A_RS06285
uniprot id: A0A1G4G6M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS11995
gene id: 1642646:ING2E5A_RS11995
uniprot id: A0A1G4G9T4
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1642646:ING2E5A RS14725
gene id: 1642646:ING2E5A_RS14725
uniprot id: A0A1G4GBI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1642646:ING2E5A RS14755
gene id: 1642646:ING2E5A_RS14755
uniprot id: A0A1G4GBD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1642646:ING2E5A RS03695
gene id: 1642646:ING2E5A_RS03695
uniprot id: A0A1G4G540
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1642646:ING2E5A RS04525
gene id: 1642646:ING2E5A_RS04525
uniprot id: A0A1G4G5G4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1642646:ING2E5A RS04015
gene id: 1642646:ING2E5A_RS04015
uniprot id: A0A1G4G550
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS08775
gene id: 1642646:ING2E5A_RS08775
uniprot id: A0A1G4G7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS10170
gene id: 1642646:ING2E5A_RS10170
uniprot id: A0A1G4G8Q4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1642646:ING2E5A RS11930
gene id: 1642646:ING2E5A_RS11930
uniprot id: A0A1G4G9P6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1642646:ING2E5A RS12675
gene id: 1642646:ING2E5A_RS12675
uniprot id: A0A1G4GA49
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1642646:ING2E5A RS04960
gene id: 1642646:ING2E5A_RS04960
uniprot id: A0A1G4G5S6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS00335
gene id: 1642646:ING2E5A_RS00335
uniprot id: A0A1G4G312
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1642646:ING2E5A RS11925
gene id: 1642646:ING2E5A_RS11925
uniprot id: A0A1G4G9Q2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS14600
gene id: 1642646:ING2E5A_RS14600
uniprot id: A0A1G4GB90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1642646:ING2E5A RS04260
gene id: 1642646:ING2E5A_RS04260
uniprot id: A0A1G4G5E7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1642646:ING2E5A RS04540
gene id: 1642646:ING2E5A_RS04540
uniprot id: A0A1G4G5L3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1642646:ING2E5A RS03310
gene id: 1642646:ING2E5A_RS03310
uniprot id: A0A1G4G4Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS07765
gene id: 1642646:ING2E5A_RS07765
uniprot id: A0A1G4G7C4
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS04435
gene id: 1642646:ING2E5A_RS04435
uniprot id: A0A1G4G5I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1642646:ING2E5A RS02355
gene id: 1642646:ING2E5A_RS02355
uniprot id: A0A1G4G4D1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1642646:ING2E5A RS13850
gene id: 1642646:ING2E5A_RS13850
uniprot id: A0A1G4GAX3
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS05670
gene id: 1642646:ING2E5A_RS05670
uniprot id: A0A1G4G651
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1642646:ING2E5A RS14155
gene id: 1642646:ING2E5A_RS14155
uniprot id: A0A1G4GB29
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1642646:ING2E5A RS06280
gene id: 1642646:ING2E5A_RS06280
uniprot id: A0A1G4G6K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1642646:ING2E5A RS03220
gene id: 1642646:ING2E5A_RS03220
uniprot id: A0A1G4G4V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1642646:ING2E5A RS00185
gene id: 1642646:ING2E5A_RS00185
uniprot id: A0A1G4G2X9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1642646:ING2E5A RS09565
gene id: 1642646:ING2E5A_RS09565
uniprot id: A0A1G4G8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1642646:ING2E5A RS14165
gene id: 1642646:ING2E5A_RS14165
uniprot id: A0A1G4GB81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1642646:ING2E5A RS05525
gene id: 1642646:ING2E5A_RS05525
uniprot id: A0A1G4G620
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1642646:ING2E5A RS10155
gene id: 1642646:ING2E5A_RS10155
uniprot id: A0A1G4G8U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1642646:ING2E5A RS00040
gene id: 1642646:ING2E5A_RS00040
uniprot id: A0A1G4G2U1
names: Similarity
messages: Belongs to the universal stress protein A family.

1642646:ING2E5A RS14000
gene id: 1642646:ING2E5A_RS14000
uniprot id: A0A1G4GAZ6
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS04740
gene id: 1642646:ING2E5A_RS04740
uniprot id: A0A1G4G5Q2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1642646:ING2E5A RS01325
gene id: 1642646:ING2E5A_RS01325
uniprot id: A0A1G4G3M7
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1642646:ING2E5A RS08075
gene id: 1642646:ING2E5A_RS08075
uniprot id: A0A1G4G7I6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1642646:ING2E5A RS02660
gene id: 1642646:ING2E5A_RS02660
uniprot id: A0A1G4G4J0
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS11760
gene id: 1642646:ING2E5A_RS11760
uniprot id: A0A1G4G9L2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1642646:ING2E5A RS03725
gene id: 1642646:ING2E5A_RS03725
uniprot id: A0A1G4G4Z7
names: Similarity
messages: Belongs to the peptidase C40 family.

1642646:ING2E5A RS03875
gene id: 1642646:ING2E5A_RS03875
uniprot id: A0A1G4G520
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1642646:ING2E5A RS11405
gene id: 1642646:ING2E5A_RS11405
uniprot id: A0A1G4G9E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1642646:ING2E5A RS14240
gene id: 1642646:ING2E5A_RS14240
uniprot id: A0A1G4GB32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1642646:ING2E5A RS06150
gene id: 1642646:ING2E5A_RS06150
uniprot id: A0A1G4G6I9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1642646:ING2E5A RS09040
gene id: 1642646:ING2E5A_RS09040
uniprot id: A0A1G4G833
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1642646:ING2E5A RS04930
gene id: 1642646:ING2E5A_RS04930
uniprot id: A0A1G4G5Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1642646:ING2E5A RS08315
gene id: 1642646:ING2E5A_RS08315
uniprot id: A0A1G4G7P4
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS07070
gene id: 1642646:ING2E5A_RS07070
uniprot id: A0A1G4G6Y4
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1642646:ING2E5A RS10705
gene id: 1642646:ING2E5A_RS10705
uniprot id: A0A1G4G946
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1642646:ING2E5A RS07825
gene id: 1642646:ING2E5A_RS07825
uniprot id: A0A1G4G7C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS06155
gene id: 1642646:ING2E5A_RS06155
uniprot id: A0A1G4G6F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1642646:ING2E5A RS03175
gene id: 1642646:ING2E5A_RS03175
uniprot id: A0A1G4G4W0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1642646:ING2E5A RS00945
gene id: 1642646:ING2E5A_RS00945
uniprot id: A0A1G4G3F0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS03515
gene id: 1642646:ING2E5A_RS03515
uniprot id: A0A1G4G4Z8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1642646:ING2E5A RS02485
gene id: 1642646:ING2E5A_RS02485
uniprot id: A0A1G4G487
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1642646:ING2E5A RS02525
gene id: 1642646:ING2E5A_RS02525
uniprot id: A0A1G4G4J4
names: Similarity
messages: Belongs to the DapA family.

1642646:ING2E5A RS00850
gene id: 1642646:ING2E5A_RS00850
uniprot id: A0A1G4G3A4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1642646:ING2E5A RS00270
gene id: 1642646:ING2E5A_RS00270
uniprot id: A0A1G4G307
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1642646:ING2E5A RS11745
gene id: 1642646:ING2E5A_RS11745
uniprot id: A0A1G4G9P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1642646:ING2E5A RS01920
gene id: 1642646:ING2E5A_RS01920
uniprot id: A0A1G4G469
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS11485
gene id: 1642646:ING2E5A_RS11485
uniprot id: A0A1G4G9F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

1642646:ING2E5A RS11410
gene id: 1642646:ING2E5A_RS11410
uniprot id: A0A1G4G9F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1642646:ING2E5A RS00165
gene id: 1642646:ING2E5A_RS00165
uniprot id: A0A1G4G363
names: Subcellular Location Annotation
messages: Cytoplasm

1642646:ING2E5A RS08855
gene id: 1642646:ING2E5A_RS08855
uniprot id: A0A1G4G7Y4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1642646:ING2E5A RS14145
gene id: 1642646:ING2E5A_RS14145
uniprot id: A0A1G4GB24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1642646:ING2E5A RS12140
gene id: 1642646:ING2E5A_RS12140
uniprot id: A0A1G4GA00
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS13490
gene id: 1642646:ING2E5A_RS13490
uniprot id: A0A1G4GAL2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS02315
gene id: 1642646:ING2E5A_RS02315
uniprot id: A0A1G4G4C7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1642646:ING2E5A RS02635
gene id: 1642646:ING2E5A_RS02635
uniprot id: A0A1G4G4H1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1642646:ING2E5A RS14580
gene id: 1642646:ING2E5A_RS14580
uniprot id: A0A1G4GB80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS12430
gene id: 1642646:ING2E5A_RS12430
uniprot id: A0A1G4GA25
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS00415
gene id: 1642646:ING2E5A_RS00415
uniprot id: A0A1G4G327
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS13165
gene id: 1642646:ING2E5A_RS13165
uniprot id: A0A1G4GAE8
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1642646:ING2E5A RS08495
gene id: 1642646:ING2E5A_RS08495
uniprot id: A0A1G4G7T9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1642646:ING2E5A RS06250
gene id: 1642646:ING2E5A_RS06250
uniprot id: A0A1G4G6G9
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS04355
gene id: 1642646:ING2E5A_RS04355
uniprot id: A0A1G4G5D7
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS07770
gene id: 1642646:ING2E5A_RS07770
uniprot id: A0A1G4G7F9
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS12070
gene id: 1642646:ING2E5A_RS12070
uniprot id: A0A1G4G9T2
names: Similarity
messages: Belongs to the peptidase C1 family.

1642646:ING2E5A RS01245
gene id: 1642646:ING2E5A_RS01245
uniprot id: A0A1G4G3V3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1642646:ING2E5A RS06470
gene id: 1642646:ING2E5A_RS06470
uniprot id: A0A1G4G6T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1642646:ING2E5A RS03885
gene id: 1642646:ING2E5A_RS03885
uniprot id: A0A1G4G519
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1642646:ING2E5A RS02385
gene id: 1642646:ING2E5A_RS02385
uniprot id: A0A1G4G470
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1642646:ING2E5A RS12835
gene id: 1642646:ING2E5A_RS12835
uniprot id: A0A1G4GA79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1642646:ING2E5A RS09120
gene id: 1642646:ING2E5A_RS09120
uniprot id: A0A1G4G856
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1642646:ING2E5A RS11490
gene id: 1642646:ING2E5A_RS11490
uniprot id: A0A1G4G9H2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS07175
gene id: 1642646:ING2E5A_RS07175
uniprot id: A0A1G4G729
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

1642646:ING2E5A RS11140
gene id: 1642646:ING2E5A_RS11140
uniprot id: A0A1G4G9A8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1642646:ING2E5A RS11800
gene id: 1642646:ING2E5A_RS11800
uniprot id: A0A1G4G9S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS09855
gene id: 1642646:ING2E5A_RS09855
uniprot id: A0A1G4G8I7
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1642646:ING2E5A RS04510
gene id: 1642646:ING2E5A_RS04510
uniprot id: A0A1G4G5K5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1642646:ING2E5A RS08940
gene id: 1642646:ING2E5A_RS08940
uniprot id: A0A1G4G838
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1642646:ING2E5A RS12110
gene id: 1642646:ING2E5A_RS12110
uniprot id: A0A1G4G9V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1642646:ING2E5A RS11945
gene id: 1642646:ING2E5A_RS11945
uniprot id: A0A1G4G9S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS00565
gene id: 1642646:ING2E5A_RS00565
uniprot id: A0A1G4G355
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS11395
gene id: 1642646:ING2E5A_RS11395
uniprot id: A0A1G4G9J8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1642646:ING2E5A RS02535
gene id: 1642646:ING2E5A_RS02535
uniprot id: A0A1G4G4C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS00970
gene id: 1642646:ING2E5A_RS00970
uniprot id: A0A1G4G3I3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1642646:ING2E5A RS01275
gene id: 1642646:ING2E5A_RS01275
uniprot id: A0A1G4G3L9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1642646:ING2E5A RS07735
gene id: 1642646:ING2E5A_RS07735
uniprot id: A0A1G4G7C2
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1642646:ING2E5A RS02575
gene id: 1642646:ING2E5A_RS02575
uniprot id: A0A1G4G4K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1642646:ING2E5A RS06595
gene id: 1642646:ING2E5A_RS06595
uniprot id: A0A1G4G6S8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1642646:ING2E5A RS07665
gene id: 1642646:ING2E5A_RS07665
uniprot id: A0A1G4G799
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1642646:ING2E5A RS02645
gene id: 1642646:ING2E5A_RS02645
uniprot id: A0A1G4G4B5
names: Similarity
messages: Belongs to the peptidase S41A family.

1642646:ING2E5A RS02325
gene id: 1642646:ING2E5A_RS02325
uniprot id: A0A1G4G456
names: Similarity
messages: Belongs to the Skp family.

1642646:ING2E5A RS06325
gene id: 1642646:ING2E5A_RS06325
uniprot id: A0A1G4G6I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1642646:ING2E5A RS08645
gene id: 1642646:ING2E5A_RS08645
uniprot id: A0A1G4G7W3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1642646:ING2E5A RS00950
gene id: 1642646:ING2E5A_RS00950
uniprot id: A0A1G4G3F9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1642646:ING2E5A RS04990
gene id: 1642646:ING2E5A_RS04990
uniprot id: A0A1G4G5U2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1642646:ING2E5A RS11310
gene id: 1642646:ING2E5A_RS11310
uniprot id: A0A1G4G9D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1642646:ING2E5A RS11660
gene id: 1642646:ING2E5A_RS11660
uniprot id: A0A1G4G9P4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1642646:ING2E5A RS11360
gene id: 1642646:ING2E5A_RS11360
uniprot id: A0A1G4G9F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1642646:ING2E5A RS10260
gene id: 1642646:ING2E5A_RS10260
uniprot id: A0A1G4G8R3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1642646:ING2E5A RS10180
gene id: 1642646:ING2E5A_RS10180
uniprot id: A0A1G4G8Q2
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS09200
gene id: 1642646:ING2E5A_RS09200
uniprot id: A0A1G4G875
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1642646:ING2E5A RS11315
gene id: 1642646:ING2E5A_RS11315
uniprot id: A0A1G4G9H1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1642646:ING2E5A RS13470
gene id: 1642646:ING2E5A_RS13470
uniprot id: A0A1G4GAQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1642646:ING2E5A RS13525
gene id: 1642646:ING2E5A_RS13525
uniprot id: A0A1G4GAM3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS11520
gene id: 1642646:ING2E5A_RS11520
uniprot id: A0A1G4G9F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1642646:ING2E5A RS14790
gene id: 1642646:ING2E5A_RS14790
uniprot id: A0A1G4GBE3
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS01900
gene id: 1642646:ING2E5A_RS01900
uniprot id: A0A1G4G3X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1642646:ING2E5A RS05120
gene id: 1642646:ING2E5A_RS05120
uniprot id: A0A1G4G5T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1642646:ING2E5A RS11740
gene id: 1642646:ING2E5A_RS11740
uniprot id: A0A1G4G9K0
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

1642646:ING2E5A RS01700
gene id: 1642646:ING2E5A_RS01700
uniprot id: A0A1G4G424
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

1642646:ING2E5A RS04495
gene id: 1642646:ING2E5A_RS04495
uniprot id: A0A1G4G5K0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1642646:ING2E5A RS06880
gene id: 1642646:ING2E5A_RS06880
uniprot id: A0A1G4G6T7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1642646:ING2E5A RS04430
gene id: 1642646:ING2E5A_RS04430
uniprot id: A0A1G4G5F9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS13115
gene id: 1642646:ING2E5A_RS13115
uniprot id: A0A1G4GAE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1642646:ING2E5A RS06320
gene id: 1642646:ING2E5A_RS06320
uniprot id: A0A1G4G6Q6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS12485
gene id: 1642646:ING2E5A_RS12485
uniprot id: A0A1G4GA63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1642646:ING2E5A RS00825
gene id: 1642646:ING2E5A_RS00825
uniprot id: A0A1G4G3L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1642646:ING2E5A RS00855
gene id: 1642646:ING2E5A_RS00855
uniprot id: A0A1G4G3A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1642646:ING2E5A RS12065
gene id: 1642646:ING2E5A_RS12065
uniprot id: A0A1G4G9U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1642646:ING2E5A RS05060
gene id: 1642646:ING2E5A_RS05060
uniprot id: A0A1G4G5U8
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS05735
gene id: 1642646:ING2E5A_RS05735
uniprot id: A0A1G4G6G1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1642646:ING2E5A RS06645
gene id: 1642646:ING2E5A_RS06645
uniprot id: A0A1G4G6R8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1642646:ING2E5A RS02210
gene id: 1642646:ING2E5A_RS02210
uniprot id: A0A1G4G436
names: Similarity
messages: Belongs to the YjdM family.

1642646:ING2E5A RS06565
gene id: 1642646:ING2E5A_RS06565
uniprot id: A0A1G4G6M9
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1642646:ING2E5A RS04110
gene id: 1642646:ING2E5A_RS04110
uniprot id: A0A1G4G5F2
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1642646:ING2E5A RS05510
gene id: 1642646:ING2E5A_RS05510
uniprot id: A0A1G4G655
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

1642646:ING2E5A RS09330
gene id: 1642646:ING2E5A_RS09330
uniprot id: A0A1G4G877
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS08415
gene id: 1642646:ING2E5A_RS08415
uniprot id: A0A1G4G7T1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1642646:ING2E5A RS11320
gene id: 1642646:ING2E5A_RS11320
uniprot id: A0A1G4G9C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1642646:ING2E5A RS08170
gene id: 1642646:ING2E5A_RS08170
uniprot id: A0A1G4G7K6
names: Similarity
messages: Belongs to the peptidase S41A family.

1642646:ING2E5A RS03630
gene id: 1642646:ING2E5A_RS03630
uniprot id: A0A1G4G4X1
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS11890
gene id: 1642646:ING2E5A_RS11890
uniprot id: A0A1G4G9M9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1642646:ING2E5A RS04335
gene id: 1642646:ING2E5A_RS04335
uniprot id: A0A1G4G5K9
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1642646:ING2E5A RS07055
gene id: 1642646:ING2E5A_RS07055
uniprot id: A0A1G4G6Z5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1642646:ING2E5A RS03480
gene id: 1642646:ING2E5A_RS03480
uniprot id: A0A1G4G523
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1642646:ING2E5A RS07730
gene id: 1642646:ING2E5A_RS07730
uniprot id: A0A1G4G7B5
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS01145
gene id: 1642646:ING2E5A_RS01145
uniprot id: A0A1G4G3S8
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS08725
gene id: 1642646:ING2E5A_RS08725
uniprot id: A0A1G4G7X0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1642646:ING2E5A RS00515
gene id: 1642646:ING2E5A_RS00515
uniprot id: A0A1G4G345
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1642646:ING2E5A RS12720
gene id: 1642646:ING2E5A_RS12720
uniprot id: A0A1G4GA61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1642646:ING2E5A RS05835
gene id: 1642646:ING2E5A_RS05835
uniprot id: A0A1G4G673
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1642646:ING2E5A RS02040
gene id: 1642646:ING2E5A_RS02040
uniprot id: A0A1G4G428
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1642646:ING2E5A RS07555
gene id: 1642646:ING2E5A_RS07555
uniprot id: A0A1G4G779
names: Similarity
messages: Belongs to the SusD family.

1642646:ING2E5A RS08055
gene id: 1642646:ING2E5A_RS08055
uniprot id: A0A1G4G7N8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS08455
gene id: 1642646:ING2E5A_RS08455
uniprot id: A0A1G4G7Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1642646:ING2E5A RS04205
gene id: 1642646:ING2E5A_RS04205
uniprot id: A0A1G4G5A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1642646:ING2E5A RS12620
gene id: 1642646:ING2E5A_RS12620
uniprot id: A0A1G4GA92
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS02445
gene id: 1642646:ING2E5A_RS02445
uniprot id: A0A1G4G496
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1642646:ING2E5A RS14800
gene id: 1642646:ING2E5A_RS14800
uniprot id: A0A1G4GBD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1642646:ING2E5A RS03705
gene id: 1642646:ING2E5A_RS03705
uniprot id: A0A1G4G4Z0
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS14395
gene id: 1642646:ING2E5A_RS14395
uniprot id: A0A1G4GB61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1642646:ING2E5A RS14865
gene id: 1642646:ING2E5A_RS14865
uniprot id: A0A1G4GBD7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1642646:ING2E5A RS11765
gene id: 1642646:ING2E5A_RS11765
uniprot id: A0A1G4G9R6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1642646:ING2E5A RS03340
gene id: 1642646:ING2E5A_RS03340
uniprot id: A0A1G4G4Z1
names: Similarity
messages: Belongs to the GARS family.

1642646:ING2E5A RS03575
gene id: 1642646:ING2E5A_RS03575
uniprot id: A0A1G4G4W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1642646:ING2E5A RS05895
gene id: 1642646:ING2E5A_RS05895
uniprot id: A0A1G4G6E6
names: Subcellular Location Annotation
messages: Membrane

1642646:ING2E5A RS09055
gene id: 1642646:ING2E5A_RS09055
uniprot id: A0A1G4G825
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

1642646:ING2E5A RS08890
gene id: 1642646:ING2E5A_RS08890
uniprot id: A0A1G4G828
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1642646:ING2E5A RS04405
gene id: 1642646:ING2E5A_RS04405
uniprot id: A0A1G4G5E1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1642646:ING2E5A RS06040
gene id: 1642646:ING2E5A_RS06040
uniprot id: A0A1G4G6F5
names: Similarity
messages: Belongs to the UPF0047 family.

1642646:ING2E5A RS14275
gene id: 1642646:ING2E5A_RS14275
uniprot id: A0A1G4GB96
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1642646:ING2E5A RS13575
gene id: 1642646:ING2E5A_RS13575
uniprot id: A0A1G4GAQ0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1642646:ING2E5A RS02140
gene id: 1642646:ING2E5A_RS02140
uniprot id: A0A1G4G429
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1642646:ING2E5A RS14700
gene id: 1642646:ING2E5A_RS14700
uniprot id: A0A1G4GBB0
names: Similarity
messages: Belongs to the RecJ family.

1642646:ING2E5A RS03510
gene id: 1642646:ING2E5A_RS03510
uniprot id: A0A1G4G4V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1642646:ING2E5A RS05760
gene id: 1642646:ING2E5A_RS05760
uniprot id: A0A1G4G6C2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1642646:ING2E5A RS04995
gene id: 1642646:ING2E5A_RS04995
uniprot id: A0A1G4G5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1642646:ING2E5A RS07845
gene id: 1642646:ING2E5A_RS07845
uniprot id: A0A1G4G7D9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1642646:ING2E5A RS11730
gene id: 1642646:ING2E5A_RS11730
uniprot id: A0A1G4G9L6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.