1631871:FOL01 RS08300
gene id: 1631871:FOL01_RS08300
uniprot id: A0A1L6RDB6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1631871:FOL01 RS10360
gene id: 1631871:FOL01_RS10360
uniprot id: A0A1L6REC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS08185
gene id: 1631871:FOL01_RS08185
uniprot id: A0A1L6RD62
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1631871:FOL01 RS07775
gene id: 1631871:FOL01_RS07775
uniprot id: A0A1L6RCP8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS07115
gene id: 1631871:FOL01_RS07115
uniprot id: A0A1L6RCH1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1631871:FOL01 RS03980
gene id: 1631871:FOL01_RS03980
uniprot id: A0A1L6RAT3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1631871:FOL01 RS03590
gene id: 1631871:FOL01_RS03590
uniprot id: A0A1L6RAF2
names: Similarity
messages: Belongs to the HAM1 NTPase family.

1631871:FOL01 RS07865
gene id: 1631871:FOL01_RS07865
uniprot id: A0A1L6RCU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1631871:FOL01 RS08945
gene id: 1631871:FOL01_RS08945
uniprot id: A0A1L6RDF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1631871:FOL01 RS11210
gene id: 1631871:FOL01_RS11210
uniprot id: A0A1L6RCW8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1631871:FOL01 RS03865
gene id: 1631871:FOL01_RS03865
uniprot id: A0A1L6RAL4
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1631871:FOL01 RS07135
gene id: 1631871:FOL01_RS07135
uniprot id: A0A1L6RCL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1631871:FOL01 RS07905
gene id: 1631871:FOL01_RS07905
uniprot id: A0A1L6RCU8
names: Similarity
messages: Belongs to the universal stress protein A family.

1631871:FOL01 RS09095
gene id: 1631871:FOL01_RS09095
uniprot id: A0A1L6RDI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1631871:FOL01 RS03510
gene id: 1631871:FOL01_RS03510
uniprot id: A0A1L6RAK0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1631871:FOL01 RS06755
gene id: 1631871:FOL01_RS06755
uniprot id: A0A1L6RC97
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS02910
gene id: 1631871:FOL01_RS02910
uniprot id: A0A1L6RA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS07285
gene id: 1631871:FOL01_RS07285
uniprot id: A0A1L6RCK2
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1631871:FOL01 RS05070
gene id: 1631871:FOL01_RS05070
uniprot id: A0A1L6RBB0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1631871:FOL01 RS02230
gene id: 1631871:FOL01_RS02230
uniprot id: A0A1L6R9P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS02830
gene id: 1631871:FOL01_RS02830
uniprot id: A0A1L6RA22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1631871:FOL01 RS08365
gene id: 1631871:FOL01_RS08365
uniprot id: A0A1L6RD45
names: Similarity
messages: Belongs to the peptidase C40 family.

1631871:FOL01 RS07340
gene id: 1631871:FOL01_RS07340
uniprot id: A0A1L6RCS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS07335
gene id: 1631871:FOL01_RS07335
uniprot id: A0A1L6RCL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

1631871:FOL01 RS06485
gene id: 1631871:FOL01_RS06485
uniprot id: A0A1L6RC17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1631871:FOL01 RS08785
gene id: 1631871:FOL01_RS08785
uniprot id: A0A1L6RDC4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1631871:FOL01 RS07965
gene id: 1631871:FOL01_RS07965
uniprot id: A0A1L6RCW7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1631871:FOL01 RS01835
gene id: 1631871:FOL01_RS01835
uniprot id: A0A1L6R9H7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS04260
gene id: 1631871:FOL01_RS04260
uniprot id: A0A1L6RAU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1631871:FOL01 RS09605
gene id: 1631871:FOL01_RS09605
uniprot id: A0A1L6RDZ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS07280
gene id: 1631871:FOL01_RS07280
uniprot id: A0A1L6RCP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1631871:FOL01 RS06200
gene id: 1631871:FOL01_RS06200
uniprot id: A0A1L6RC00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1631871:FOL01 RS04155
gene id: 1631871:FOL01_RS04155
uniprot id: A0A1L6RAT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1631871:FOL01 RS06760
gene id: 1631871:FOL01_RS06760
uniprot id: A0A1L6RC74
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1631871:FOL01 RS07110
gene id: 1631871:FOL01_RS07110
uniprot id: A0A1L6RCG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1631871:FOL01 RS01365
gene id: 1631871:FOL01_RS01365
uniprot id: A0A1L6R9C4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1631871:FOL01 RS07450
gene id: 1631871:FOL01_RS07450
uniprot id: A0A1L6RCN5
names: Similarity
messages: Belongs to the UPF0758 family.

1631871:FOL01 RS01925
gene id: 1631871:FOL01_RS01925
uniprot id: A0A1L6R9J8
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1631871:FOL01 RS03210
gene id: 1631871:FOL01_RS03210
uniprot id: A0A1L6RAD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1631871:FOL01 RS05800
gene id: 1631871:FOL01_RS05800
uniprot id: A0A1L6RBW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1631871:FOL01 RS06475
gene id: 1631871:FOL01_RS06475
uniprot id: A0A1L6RC46
names: Similarity
messages: Belongs to the UPF0473 family.

1631871:FOL01 RS04000
gene id: 1631871:FOL01_RS04000
uniprot id: A0A1L6RAU4
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1631871:FOL01 RS02650
gene id: 1631871:FOL01_RS02650
uniprot id: A0A1L6RA31
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1631871:FOL01 RS02435
gene id: 1631871:FOL01_RS02435
uniprot id: A0A1L6R9U2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1631871:FOL01 RS05195
gene id: 1631871:FOL01_RS05195
uniprot id: A0A1L6RBB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1631871:FOL01 RS09420
gene id: 1631871:FOL01_RS09420
uniprot id: A0A1L6RDP0
names: Similarity
messages: Belongs to the peptidase M13 family.

1631871:FOL01 RS07825
gene id: 1631871:FOL01_RS07825
uniprot id: A0A1L6RCQ7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1631871:FOL01 RS01525
gene id: 1631871:FOL01_RS01525
uniprot id: A0A1L6R9F3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1631871:FOL01 RS10535
gene id: 1631871:FOL01_RS10535
uniprot id: A0A1L6REA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1631871:FOL01 RS02690
gene id: 1631871:FOL01_RS02690
uniprot id: A0A1L6RA40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS00520
gene id: 1631871:FOL01_RS00520
uniprot id: A0A1L6R8X9
names: Similarity
messages: Belongs to the catalase family.

1631871:FOL01 RS06310
gene id: 1631871:FOL01_RS06310
uniprot id: A0A1L6RC16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1631871:FOL01 RS04235
gene id: 1631871:FOL01_RS04235
uniprot id: A0A1L6RB12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1631871:FOL01 RS08650
gene id: 1631871:FOL01_RS08650
uniprot id: A0A1L6RD76
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS08820
gene id: 1631871:FOL01_RS08820
uniprot id: A0A1L6RDC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1631871:FOL01 RS10745
gene id: 1631871:FOL01_RS10745
uniprot id: A0A1L6REF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS04115
gene id: 1631871:FOL01_RS04115
uniprot id: A0A1L6RAS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1631871:FOL01 RS01320
gene id: 1631871:FOL01_RS01320
uniprot id: A0A1L6R969
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS08420
gene id: 1631871:FOL01_RS08420
uniprot id: A0A1L6RD50
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1631871:FOL01 RS08705
gene id: 1631871:FOL01_RS08705
uniprot id: A0A1L6RD84
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1631871:FOL01 RS00190
gene id: 1631871:FOL01_RS00190
uniprot id: A0A1L6R8S0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS09165
gene id: 1631871:FOL01_RS09165
uniprot id: A0A1L6RDN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS08400
gene id: 1631871:FOL01_RS08400
uniprot id: A0A1L6RDA3
names: Similarity
messages: Belongs to the TPP enzyme family.

1631871:FOL01 RS01675
gene id: 1631871:FOL01_RS01675
uniprot id: A0A1L6R9H0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS08415
gene id: 1631871:FOL01_RS08415
uniprot id: A0A1L6RDD2
names: Similarity
messages: Belongs to the universal stress protein A family.

1631871:FOL01 RS07500
gene id: 1631871:FOL01_RS07500
uniprot id: A0A1L6RCP6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1631871:FOL01 RS00350
gene id: 1631871:FOL01_RS00350
uniprot id: A0A1L6R8R2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1631871:FOL01 RS07985
gene id: 1631871:FOL01_RS07985
uniprot id: A0A1L6RCU2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

1631871:FOL01 RS02685
gene id: 1631871:FOL01_RS02685
uniprot id: A0A1L6R9X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS03550
gene id: 1631871:FOL01_RS03550
uniprot id: A0A1L6RAD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S15 family.
messages: Cytoplasm
messages: Homodimer.
messages: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

1631871:FOL01 RS08350
gene id: 1631871:FOL01_RS08350
uniprot id: A0A1L6RDC9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1631871:FOL01 RS08460
gene id: 1631871:FOL01_RS08460
uniprot id: A0A1L6RD65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1631871:FOL01 RS06600
gene id: 1631871:FOL01_RS06600
uniprot id: A0A1L6RC68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1631871:FOL01 RS07355
gene id: 1631871:FOL01_RS07355
uniprot id: A0A1L6RCL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS08770
gene id: 1631871:FOL01_RS08770
uniprot id: A0A1L6RDK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1631871:FOL01 RS04165
gene id: 1631871:FOL01_RS04165
uniprot id: A0A1L6RAU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS06235
gene id: 1631871:FOL01_RS06235
uniprot id: A0A1L6RC55
names: Similarity
messages: Belongs to the UPF0346 family.

1631871:FOL01 RS04250
gene id: 1631871:FOL01_RS04250
uniprot id: A0A1L6RAW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1631871:FOL01 RS01805
gene id: 1631871:FOL01_RS01805
uniprot id: A0A1L6R9L7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1631871:FOL01 RS09725
gene id: 1631871:FOL01_RS09725
uniprot id: A0A1L6RDV6
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS09170
gene id: 1631871:FOL01_RS09170
uniprot id: A0A1L6RDH0
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS05475
gene id: 1631871:FOL01_RS05475
uniprot id: A0A1L6RBJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1631871:FOL01 RS07495
gene id: 1631871:FOL01_RS07495
uniprot id: A0A1L6RCW2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1631871:FOL01 RS04750
gene id: 1631871:FOL01_RS04750
uniprot id: A0A1L6RBA7
names: Function
names: Similarity
messages: Belongs to the CpsD/CapB family.
messages: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide.

1631871:FOL01 RS03325
gene id: 1631871:FOL01_RS03325
uniprot id: A0A1L6RAC1
names: Similarity
messages: Belongs to the DEAD box helicase family.

1631871:FOL01 RS03300
gene id: 1631871:FOL01_RS03300
uniprot id: A0A1L6RAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1631871:FOL01 RS02015
gene id: 1631871:FOL01_RS02015
uniprot id: A0A1L6R9Q7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1631871:FOL01 RS01690
gene id: 1631871:FOL01_RS01690
uniprot id: A0A1L6R9I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1631871:FOL01 RS01485
gene id: 1631871:FOL01_RS01485
uniprot id: A0A1L6R9F2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS09810
gene id: 1631871:FOL01_RS09810
uniprot id: A0A1L6RDW1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS10315
gene id: 1631871:FOL01_RS10315
uniprot id: A0A1L6REC0
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS08950
gene id: 1631871:FOL01_RS08950
uniprot id: A0A1L6RDG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1631871:FOL01 RS08575
gene id: 1631871:FOL01_RS08575
uniprot id: A0A1L6RD51
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

1631871:FOL01 RS09335
gene id: 1631871:FOL01_RS09335
uniprot id: A0A1L6RDR6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1631871:FOL01 RS10510
gene id: 1631871:FOL01_RS10510
uniprot id: A0A1L6REF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS03445
gene id: 1631871:FOL01_RS03445
uniprot id: A0A1L6RAC2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS08980
gene id: 1631871:FOL01_RS08980
uniprot id: A0A1L6RDP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1631871:FOL01 RS08505
gene id: 1631871:FOL01_RS08505
uniprot id: A0A1L6RDC7
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS08880
gene id: 1631871:FOL01_RS08880
uniprot id: A0A1L6RDD3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1631871:FOL01 RS09670
gene id: 1631871:FOL01_RS09670
uniprot id: A0A1L6RDT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1631871:FOL01 RS03475
gene id: 1631871:FOL01_RS03475
uniprot id: A0A1L6RAE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS01325
gene id: 1631871:FOL01_RS01325
uniprot id: A0A1L6R9B3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1631871:FOL01 RS00195
gene id: 1631871:FOL01_RS00195
uniprot id: A0A1L6R8Q3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1631871:FOL01 RS02900
gene id: 1631871:FOL01_RS02900
uniprot id: A0A1L6RA91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS05230
gene id: 1631871:FOL01_RS05230
uniprot id: A0A1L6RBF0
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS06555
gene id: 1631871:FOL01_RS06555
uniprot id: A0A1L6RC61
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1631871:FOL01 RS00925
gene id: 1631871:FOL01_RS00925
uniprot id: A0A1L6R916
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1631871:FOL01 RS06065
gene id: 1631871:FOL01_RS06065
uniprot id: A0A1L6RBW3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1631871:FOL01 RS00400
gene id: 1631871:FOL01_RS00400
uniprot id: A0A1L6R8S4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1631871:FOL01 RS08070
gene id: 1631871:FOL01_RS08070
uniprot id: A0A1L6RCV3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1631871:FOL01 RS09250
gene id: 1631871:FOL01_RS09250
uniprot id: A0A1L6RDK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1631871:FOL01 RS01785
gene id: 1631871:FOL01_RS01785
uniprot id: A0A1L6R9G7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1631871:FOL01 RS01870
gene id: 1631871:FOL01_RS01870
uniprot id: A0A1L6R9L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1631871:FOL01 RS10325
gene id: 1631871:FOL01_RS10325
uniprot id: A0A1L6RED7
names: Similarity
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Homotetramer.

1631871:FOL01 RS07570
gene id: 1631871:FOL01_RS07570
uniprot id: A0A1L6RCR0
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS03165
gene id: 1631871:FOL01_RS03165
uniprot id: A0A1L6RAA2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1631871:FOL01 RS03520
gene id: 1631871:FOL01_RS03520
uniprot id: A0A1L6RAF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1631871:FOL01 RS07315
gene id: 1631871:FOL01_RS07315
uniprot id: A0A1L6RCI0
names: Similarity
messages: Belongs to the YggT family.

1631871:FOL01 RS04310
gene id: 1631871:FOL01_RS04310
uniprot id: A0A1L6RAW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1631871:FOL01 RS06565
gene id: 1631871:FOL01_RS06565
uniprot id: A0A1L6RC95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS08280
gene id: 1631871:FOL01_RS08280
uniprot id: A0A1L6RD73
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1631871:FOL01 RS05145
gene id: 1631871:FOL01_RS05145
uniprot id: A0A1L6RBA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS05090
gene id: 1631871:FOL01_RS05090
uniprot id: A0A1L6RBG6
names: Subcellular Location Annotation
messages: Cytoplasm

1631871:FOL01 RS07575
gene id: 1631871:FOL01_RS07575
uniprot id: A0A1L6RCR3
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS00280
gene id: 1631871:FOL01_RS00280
uniprot id: A0A1L6R8S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1631871:FOL01 RS00560
gene id: 1631871:FOL01_RS00560
uniprot id: A0A1L6R8U0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1631871:FOL01 RS02560
gene id: 1631871:FOL01_RS02560
uniprot id: A0A1L6RA03
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1631871:FOL01 RS08935
gene id: 1631871:FOL01_RS08935
uniprot id: A0A1L6RDE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1631871:FOL01 RS08860
gene id: 1631871:FOL01_RS08860
uniprot id: A0A1L6RDB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1631871:FOL01 RS02750
gene id: 1631871:FOL01_RS02750
uniprot id: A0A1L6RA55
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1631871:FOL01 RS10525
gene id: 1631871:FOL01_RS10525
uniprot id: A0A1L6REA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS06855
gene id: 1631871:FOL01_RS06855
uniprot id: A0A1L6RCB6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1631871:FOL01 RS09340
gene id: 1631871:FOL01_RS09340
uniprot id: A0A1L6RDJ7
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1631871:FOL01 RS00055
gene id: 1631871:FOL01_RS00055
uniprot id: A0A1L6R8N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS00525
gene id: 1631871:FOL01_RS00525
uniprot id: A0A1L6R8T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1631871:FOL01 RS08780
gene id: 1631871:FOL01_RS08780
uniprot id: A0A1L6RD88
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1631871:FOL01 RS05995
gene id: 1631871:FOL01_RS05995
uniprot id: A0A1L6RBS2
names: Similarity
messages: Belongs to the universal stress protein A family.

1631871:FOL01 RS01035
gene id: 1631871:FOL01_RS01035
uniprot id: A0A1L6R935
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1631871:FOL01 RS08955
gene id: 1631871:FOL01_RS08955
uniprot id: A0A1L6RDC1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1631871:FOL01 RS10345
gene id: 1631871:FOL01_RS10345
uniprot id: A0A1L6RE47
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1631871:FOL01 RS08865
gene id: 1631871:FOL01_RS08865
uniprot id: A0A1L6RDJ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1631871:FOL01 RS02635
gene id: 1631871:FOL01_RS02635
uniprot id: A0A1L6R9W8
names: Similarity
messages: Belongs to the asp23 family.

1631871:FOL01 RS06650
gene id: 1631871:FOL01_RS06650
uniprot id: A0A1L6RC80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1631871:FOL01 RS08985
gene id: 1631871:FOL01_RS08985
uniprot id: A0A1L6RDF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1631871:FOL01 RS03405
gene id: 1631871:FOL01_RS03405
uniprot id: A0A1L6RAA6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS01775
gene id: 1631871:FOL01_RS01775
uniprot id: A0A1L6R9H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS10685
gene id: 1631871:FOL01_RS10685
uniprot id: A0A1L6REC3
names: Similarity
messages: Belongs to the Dps family.

1631871:FOL01 RS02385
gene id: 1631871:FOL01_RS02385
uniprot id: A0A1L6R9V5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS00410
gene id: 1631871:FOL01_RS00410
uniprot id: A0A1L6R8R1
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS01945
gene id: 1631871:FOL01_RS01945
uniprot id: A0A1L6R9N2
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS08270
gene id: 1631871:FOL01_RS08270
uniprot id: A0A1L6RD28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS10370
gene id: 1631871:FOL01_RS10370
uniprot id: A0A1L6REE5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1631871:FOL01 RS06795
gene id: 1631871:FOL01_RS06795
uniprot id: A0A1L6RC96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

1631871:FOL01 RS01505
gene id: 1631871:FOL01_RS01505
uniprot id: A0A1L6R9C1
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1631871:FOL01 RS06515
gene id: 1631871:FOL01_RS06515
uniprot id: A0A1L6RC59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1631871:FOL01 RS05635
gene id: 1631871:FOL01_RS05635
uniprot id: A0A1L6RBN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

1631871:FOL01 RS06450
gene id: 1631871:FOL01_RS06450
uniprot id: A0A1L6RC93
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1631871:FOL01 RS07220
gene id: 1631871:FOL01_RS07220
uniprot id: A0A1L6RCG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1631871:FOL01 RS06220
gene id: 1631871:FOL01_RS06220
uniprot id: A0A1L6RBW6
names: Similarity
messages: Belongs to the DprA/Smf family.

1631871:FOL01 RS08840
gene id: 1631871:FOL01_RS08840
uniprot id: A0A1L6RDD1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1631871:FOL01 RS08615
gene id: 1631871:FOL01_RS08615
uniprot id: A0A1L6RDH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1631871:FOL01 RS00580
gene id: 1631871:FOL01_RS00580
uniprot id: A0A1L6R8V6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1631871:FOL01 RS02215
gene id: 1631871:FOL01_RS02215
uniprot id: A0A1L6R9S4
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1631871:FOL01 RS04560
gene id: 1631871:FOL01_RS04560
uniprot id: A0A1L6RB02
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS00170
gene id: 1631871:FOL01_RS00170
uniprot id: A0A1L6R8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1631871:FOL01 RS01430
gene id: 1631871:FOL01_RS01430
uniprot id: A0A1L6R9E1
names: Similarity
messages: Belongs to the threonine synthase family.

1631871:FOL01 RS03400
gene id: 1631871:FOL01_RS03400
uniprot id: A0A1L6RAI9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1631871:FOL01 RS00035
gene id: 1631871:FOL01_RS00035
uniprot id: A0A1L6R8I9
names: Similarity
messages: Belongs to the peptidase C69 family.

1631871:FOL01 RS05050
gene id: 1631871:FOL01_RS05050
uniprot id: A0A1L6RB95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS07975
gene id: 1631871:FOL01_RS07975
uniprot id: A0A1L6RCT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1631871:FOL01 RS07815
gene id: 1631871:FOL01_RS07815
uniprot id: A0A1L6RCT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1631871:FOL01 RS05345
gene id: 1631871:FOL01_RS05345
uniprot id: A0A1L6RBE7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS03780
gene id: 1631871:FOL01_RS03780
uniprot id: A0A1L6RAH7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1631871:FOL01 RS08750
gene id: 1631871:FOL01_RS08750
uniprot id: A0A1L6RDF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS09260
gene id: 1631871:FOL01_RS09260
uniprot id: A0A1L6RDL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1631871:FOL01 RS02795
gene id: 1631871:FOL01_RS02795
uniprot id: A0A1L6R9Z5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1631871:FOL01 RS07120
gene id: 1631871:FOL01_RS07120
uniprot id: A0A1L6RCE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1631871:FOL01 RS03490
gene id: 1631871:FOL01_RS03490
uniprot id: A0A1L6RAH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS04255
gene id: 1631871:FOL01_RS04255
uniprot id: A0A1L6RAV2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1631871:FOL01 RS01230
gene id: 1631871:FOL01_RS01230
uniprot id: A0A1L6R9A9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1631871:FOL01 RS05115
gene id: 1631871:FOL01_RS05115
uniprot id: A0A1L6RBD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1631871:FOL01 RS00140
gene id: 1631871:FOL01_RS00140
uniprot id: A0A1L6R8R0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS07545
gene id: 1631871:FOL01_RS07545
uniprot id: A0A1L6RCQ9
names: Subcellular Location Annotation
messages: Cytoplasm

1631871:FOL01 RS10025
gene id: 1631871:FOL01_RS10025
uniprot id: A0A1L6RE56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1631871:FOL01 RS09520
gene id: 1631871:FOL01_RS09520
uniprot id: A0A1L6RDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS07125
gene id: 1631871:FOL01_RS07125
uniprot id: A0A1L6RCK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1631871:FOL01 RS09020
gene id: 1631871:FOL01_RS09020
uniprot id: A0A1L6RDM5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1631871:FOL01 RS03115
gene id: 1631871:FOL01_RS03115
uniprot id: A0A1L6RA92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1631871:FOL01 RS08435
gene id: 1631871:FOL01_RS08435
uniprot id: A0A1L6RD56
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS04280
gene id: 1631871:FOL01_RS04280
uniprot id: A0A1L6RAU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1631871:FOL01 RS03835
gene id: 1631871:FOL01_RS03835
uniprot id: A0A1L6RAQ5
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1631871:FOL01 RS01225
gene id: 1631871:FOL01_RS01225
uniprot id: A0A1L6R967
names: Similarity
messages: Belongs to the peptidase C56 family.

1631871:FOL01 RS08545
gene id: 1631871:FOL01_RS08545
uniprot id: A0A1L6RDB3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1631871:FOL01 RS09320
gene id: 1631871:FOL01_RS09320
uniprot id: A0A1L6RDM3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1631871:FOL01 RS01930
gene id: 1631871:FOL01_RS01930
uniprot id: A0A1L6R9M7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1631871:FOL01 RS06175
gene id: 1631871:FOL01_RS06175
uniprot id: A0A1L6RC28
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1631871:FOL01 RS03240
gene id: 1631871:FOL01_RS03240
uniprot id: A0A1L6RAD5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1631871:FOL01 RS06325
gene id: 1631871:FOL01_RS06325
uniprot id: A0A1L6RC54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS01435
gene id: 1631871:FOL01_RS01435
uniprot id: A0A1L6R9A5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1631871:FOL01 RS09750
gene id: 1631871:FOL01_RS09750
uniprot id: A0A1L6RDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Ycf16 family.
messages: Membrane

1631871:FOL01 RS06000
gene id: 1631871:FOL01_RS06000
uniprot id: A0A1L6RC05
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS01790
gene id: 1631871:FOL01_RS01790
uniprot id: A0A1L6R9G5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1631871:FOL01 RS09085
gene id: 1631871:FOL01_RS09085
uniprot id: A0A1L6RDH7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1631871:FOL01 RS00355
gene id: 1631871:FOL01_RS00355
uniprot id: A0A1L6R8T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS01345
gene id: 1631871:FOL01_RS01345
uniprot id: A0A1L6R992
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1631871:FOL01 RS01100
gene id: 1631871:FOL01_RS01100
uniprot id: A0A1L6R974
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS04430
gene id: 1631871:FOL01_RS04430
uniprot id: A0A1L6RB38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1631871:FOL01 RS01940
gene id: 1631871:FOL01_RS01940
uniprot id: A0A1L6R9J4
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS10205
gene id: 1631871:FOL01_RS10205
uniprot id: A0A1L6RE60
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS03235
gene id: 1631871:FOL01_RS03235
uniprot id: A0A1L6RA69
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1631871:FOL01 RS07320
gene id: 1631871:FOL01_RS07320
uniprot id: A0A1L6RCP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1631871:FOL01 RS09455
gene id: 1631871:FOL01_RS09455
uniprot id: A0A1L6RDU2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1631871:FOL01 RS04645
gene id: 1631871:FOL01_RS04645
uniprot id: A0A1L6RB09
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1631871:FOL01 RS01960
gene id: 1631871:FOL01_RS01960
uniprot id: A0A1L6R9K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1631871:FOL01 RS00030
gene id: 1631871:FOL01_RS00030
uniprot id: A0A1L6R8M3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1631871:FOL01 RS01495
gene id: 1631871:FOL01_RS01495
uniprot id: A0A1L6R9F8
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

1631871:FOL01 RS10530
gene id: 1631871:FOL01_RS10530
uniprot id: A0A1L6RE82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1631871:FOL01 RS03110
gene id: 1631871:FOL01_RS03110
uniprot id: A0A1L6RAB4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1631871:FOL01 RS09365
gene id: 1631871:FOL01_RS09365
uniprot id: A0A1L6RDV7
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS10095
gene id: 1631871:FOL01_RS10095
uniprot id: A0A1L6RDZ5
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS10220
gene id: 1631871:FOL01_RS10220
uniprot id: A0A1L6REA1
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS04470
gene id: 1631871:FOL01_RS04470
uniprot id: A0A1L6RAZ8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1631871:FOL01 RS09635
gene id: 1631871:FOL01_RS09635
uniprot id: A0A1L6RDX2
names: Subcellular Location Annotation
messages: Cell membrane

1631871:FOL01 RS08855
gene id: 1631871:FOL01_RS08855
uniprot id: A0A1L6RDH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1631871:FOL01 RS05980
gene id: 1631871:FOL01_RS05980
uniprot id: A0A1L6RBV0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1631871:FOL01 RS08445
gene id: 1631871:FOL01_RS08445
uniprot id: A0A1L6RDA5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1631871:FOL01 RS03595
gene id: 1631871:FOL01_RS03595
uniprot id: A0A1L6RAN3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS06700
gene id: 1631871:FOL01_RS06700
uniprot id: A0A1L6RC90
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS08720
gene id: 1631871:FOL01_RS08720
uniprot id: A0A1L6RDJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1631871:FOL01 RS03055
gene id: 1631871:FOL01_RS03055
uniprot id: A0A1L6RA80
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1631871:FOL01 RS07410
gene id: 1631871:FOL01_RS07410
uniprot id: A0A1L6RCM1
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1631871:FOL01 RS07995
gene id: 1631871:FOL01_RS07995
uniprot id: A0A1L6RCX3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1631871:FOL01 RS07805
gene id: 1631871:FOL01_RS07805
uniprot id: A0A1L6RCT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

1631871:FOL01 RS05965
gene id: 1631871:FOL01_RS05965
uniprot id: A0A1L6RBV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

1631871:FOL01 RS05135
gene id: 1631871:FOL01_RS05135
uniprot id: A0A1L6RB90
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1631871:FOL01 RS00290
gene id: 1631871:FOL01_RS00290
uniprot id: A0A1L6R8U1
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS03375
gene id: 1631871:FOL01_RS03375
uniprot id: A0A1L6RAD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1631871:FOL01 RS04135
gene id: 1631871:FOL01_RS04135
uniprot id: A0A1L6RAZ4
names: Similarity
messages: Belongs to the UPF0213 family.

1631871:FOL01 RS02965
gene id: 1631871:FOL01_RS02965
uniprot id: A0A1L6RA54
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1631871:FOL01 RS07305
gene id: 1631871:FOL01_RS07305
uniprot id: A0A1L6RCK4
names: Subcellular Location Annotation
messages: Cytoplasm

1631871:FOL01 RS04435
gene id: 1631871:FOL01_RS04435
uniprot id: A0A1L6RAW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS04150
gene id: 1631871:FOL01_RS04150
uniprot id: A0A1L6RAV0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS02030
gene id: 1631871:FOL01_RS02030
uniprot id: A0A1L6R9P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

1631871:FOL01 RS07345
gene id: 1631871:FOL01_RS07345
uniprot id: A0A1L6RCL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1631871:FOL01 RS02080
gene id: 1631871:FOL01_RS02080
uniprot id: A0A1L6R9Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1631871:FOL01 RS00100
gene id: 1631871:FOL01_RS00100
uniprot id: A0A1L6R8K7
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1631871:FOL01 RS09390
gene id: 1631871:FOL01_RS09390
uniprot id: A0A1L6RDN2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1631871:FOL01 RS04370
gene id: 1631871:FOL01_RS04370
uniprot id: A0A1L6RAY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1631871:FOL01 RS10065
gene id: 1631871:FOL01_RS10065
uniprot id: A0A1L6RDY8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS09240
gene id: 1631871:FOL01_RS09240
uniprot id: A0A1L6RDH8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS07095
gene id: 1631871:FOL01_RS07095
uniprot id: A0A1L6RCM4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS04780
gene id: 1631871:FOL01_RS04780
uniprot id: A0A1L6RBA6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1631871:FOL01 RS09280
gene id: 1631871:FOL01_RS09280
uniprot id: A0A1L6RDI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1631871:FOL01 RS08910
gene id: 1631871:FOL01_RS08910
uniprot id: A0A1L6RDC0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1631871:FOL01 RS09935
gene id: 1631871:FOL01_RS09935
uniprot id: A0A1L6RE42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS06610
gene id: 1631871:FOL01_RS06610
uniprot id: A0A1L6RC36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1631871:FOL01 RS01555
gene id: 1631871:FOL01_RS01555
uniprot id: A0A1L6R9D0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1631871:FOL01 RS04415
gene id: 1631871:FOL01_RS04415
uniprot id: A0A1L6RAX4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1631871:FOL01 RS09985
gene id: 1631871:FOL01_RS09985
uniprot id: A0A1L6RE53
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

1631871:FOL01 RS08080
gene id: 1631871:FOL01_RS08080
uniprot id: A0A1L6RCW0
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS01190
gene id: 1631871:FOL01_RS01190
uniprot id: A0A1L6R962
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1631871:FOL01 RS01330
gene id: 1631871:FOL01_RS01330
uniprot id: A0A1L6R985
names: Similarity
messages: Belongs to the TPP enzyme family.

1631871:FOL01 RS10595
gene id: 1631871:FOL01_RS10595
uniprot id: A0A1L6REB9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1631871:FOL01 RS01670
gene id: 1631871:FOL01_RS01670
uniprot id: A0A1L6R9F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1631871:FOL01 RS08385
gene id: 1631871:FOL01_RS08385
uniprot id: A0A1L6RD05
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1631871:FOL01 RS09040
gene id: 1631871:FOL01_RS09040
uniprot id: A0A1L6RDE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1631871:FOL01 RS04340
gene id: 1631871:FOL01_RS04340
uniprot id: A0A1L6RAU8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Homohexamer.

1631871:FOL01 RS00360
gene id: 1631871:FOL01_RS00360
uniprot id: A0A1L6R8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS09855
gene id: 1631871:FOL01_RS09855
uniprot id: A0A1L6RDU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS00020
gene id: 1631871:FOL01_RS00020
uniprot id: A0A1L6R8L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1631871:FOL01 RS03150
gene id: 1631871:FOL01_RS03150
uniprot id: A0A1L6RAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS10225
gene id: 1631871:FOL01_RS10225
uniprot id: A0A1L6RE48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS08250
gene id: 1631871:FOL01_RS08250
uniprot id: A0A1L6RDA6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1631871:FOL01 RS04400
gene id: 1631871:FOL01_RS04400
uniprot id: A0A1L6RB33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1631871:FOL01 RS10015
gene id: 1631871:FOL01_RS10015
uniprot id: A0A1L6RE18
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1631871:FOL01 RS01310
gene id: 1631871:FOL01_RS01310
uniprot id: A0A1L6R977
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

1631871:FOL01 RS01545
gene id: 1631871:FOL01_RS01545
uniprot id: A0A1L6R9G8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1631871:FOL01 RS10000
gene id: 1631871:FOL01_RS10000
uniprot id: A0A1L6RE00
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1631871:FOL01 RS05575
gene id: 1631871:FOL01_RS05575
uniprot id: A0A1L6RBI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1631871:FOL01 RS01560
gene id: 1631871:FOL01_RS01560
uniprot id: A0A1L6R9F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1631871:FOL01 RS05355
gene id: 1631871:FOL01_RS05355
uniprot id: A0A1L6RBM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1631871:FOL01 RS00955
gene id: 1631871:FOL01_RS00955
uniprot id: A0A1L6R915
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1631871:FOL01 RS01165
gene id: 1631871:FOL01_RS01165
uniprot id: A0A1L6R938
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1631871:FOL01 RS06510
gene id: 1631871:FOL01_RS06510
uniprot id: A0A1L6RCB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1631871:FOL01 RS10430
gene id: 1631871:FOL01_RS10430
uniprot id: A0A1L6RE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1631871:FOL01 RS03640
gene id: 1631871:FOL01_RS03640
uniprot id: A0A1L6RAG6
names: Similarity
messages: Belongs to the FGGY kinase family.

1631871:FOL01 RS04800
gene id: 1631871:FOL01_RS04800
uniprot id: A0A1L6RBB6
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1631871:FOL01 RS03575
gene id: 1631871:FOL01_RS03575
uniprot id: A0A1L6RAF1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1631871:FOL01 RS10010
gene id: 1631871:FOL01_RS10010
uniprot id: A0A1L6RE01
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1631871:FOL01 RS01045
gene id: 1631871:FOL01_RS01045
uniprot id: A0A1L6R963
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1631871:FOL01 RS01215
gene id: 1631871:FOL01_RS01215
uniprot id: A0A1L6R949
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the N-terminal section; belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

1631871:FOL01 RS09175
gene id: 1631871:FOL01_RS09175
uniprot id: A0A1L6RDQ3
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS07080
gene id: 1631871:FOL01_RS07080
uniprot id: A0A1L6RCD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1631871:FOL01 RS03820
gene id: 1631871:FOL01_RS03820
uniprot id: A0A1L6RAK8
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS01535
gene id: 1631871:FOL01_RS01535
uniprot id: A0A1L6R9G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1631871:FOL01 RS02585
gene id: 1631871:FOL01_RS02585
uniprot id: A0A1L6R9X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1631871:FOL01 RS09015
gene id: 1631871:FOL01_RS09015
uniprot id: A0A1L6RDE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1631871:FOL01 RS07845
gene id: 1631871:FOL01_RS07845
uniprot id: A0A1L6RCU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1631871:FOL01 RS02065
gene id: 1631871:FOL01_RS02065
uniprot id: A0A1L6R9R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1631871:FOL01 RS10260
gene id: 1631871:FOL01_RS10260
uniprot id: A0A1L6REA5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1631871:FOL01 RS08215
gene id: 1631871:FOL01_RS08215
uniprot id: A0A1L6RD15
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1631871:FOL01 RS00110
gene id: 1631871:FOL01_RS00110
uniprot id: A0A1L6R8L1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS09200
gene id: 1631871:FOL01_RS09200
uniprot id: A0A1L6RDK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1631871:FOL01 RS04230
gene id: 1631871:FOL01_RS04230
uniprot id: A0A1L6RAT0
names: Similarity
messages: Belongs to the CvfB family.

1631871:FOL01 RS05000
gene id: 1631871:FOL01_RS05000
uniprot id: A0A1L6RB81
names: Similarity
messages: Belongs to the ThiD family.

1631871:FOL01 RS03135
gene id: 1631871:FOL01_RS03135
uniprot id: A0A1L6RA46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1631871:FOL01 RS03250
gene id: 1631871:FOL01_RS03250
uniprot id: A0A1L6RAF6
names: Similarity
messages: Belongs to the fabD family.

1631871:FOL01 RS08890
gene id: 1631871:FOL01_RS08890
uniprot id: A0A1L6RDE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1631871:FOL01 RS09920
gene id: 1631871:FOL01_RS09920
uniprot id: A0A1L6RDV9
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS00160
gene id: 1631871:FOL01_RS00160
uniprot id: A0A1L6R8L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1631871:FOL01 RS07750
gene id: 1631871:FOL01_RS07750
uniprot id: A0A1L6RCZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1631871:FOL01 RS04205
gene id: 1631871:FOL01_RS04205
uniprot id: A0A1L6RAT9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1631871:FOL01 RS09585
gene id: 1631871:FOL01_RS09585
uniprot id: A0A1L6RDX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS02760
gene id: 1631871:FOL01_RS02760
uniprot id: A0A1L6RA52
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1631871:FOL01 RS08225
gene id: 1631871:FOL01_RS08225
uniprot id: A0A1L6RCX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1631871:FOL01 RS02720
gene id: 1631871:FOL01_RS02720
uniprot id: A0A1L6RA00
names: Similarity
messages: Belongs to the universal stress protein A family.

1631871:FOL01 RS07325
gene id: 1631871:FOL01_RS07325
uniprot id: A0A1L6RCI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1631871:FOL01 RS07400
gene id: 1631871:FOL01_RS07400
uniprot id: A0A1L6RCL8
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS03195
gene id: 1631871:FOL01_RS03195
uniprot id: A0A1L6RA65
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1631871:FOL01 RS08450
gene id: 1631871:FOL01_RS08450
uniprot id: A0A1L6RD31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1631871:FOL01 RS00070
gene id: 1631871:FOL01_RS00070
uniprot id: A0A1L6R8N1
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS01685
gene id: 1631871:FOL01_RS01685
uniprot id: A0A1L6R9E5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1631871:FOL01 RS08295
gene id: 1631871:FOL01_RS08295
uniprot id: A0A1L6RD33
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1631871:FOL01 RS07720
gene id: 1631871:FOL01_RS07720
uniprot id: A0A1L6RCS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1631871:FOL01 RS08425
gene id: 1631871:FOL01_RS08425
uniprot id: A0A1L6RD22
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS07150
gene id: 1631871:FOL01_RS07150
uniprot id: A0A1L6RCH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1631871:FOL01 RS09705
gene id: 1631871:FOL01_RS09705
uniprot id: A0A1L6RE16
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

1631871:FOL01 RS03120
gene id: 1631871:FOL01_RS03120
uniprot id: A0A1L6RA76
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1631871:FOL01 RS03295
gene id: 1631871:FOL01_RS03295
uniprot id: A0A1L6RA93
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1631871:FOL01 RS09110
gene id: 1631871:FOL01_RS09110
uniprot id: A0A1L6RDM1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1631871:FOL01 RS09395
gene id: 1631871:FOL01_RS09395
uniprot id: A0A1L6RDQ1
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1631871:FOL01 RS01595
gene id: 1631871:FOL01_RS01595
uniprot id: A0A1L6R9H8
names: Similarity
messages: Belongs to the GARS family.

1631871:FOL01 RS03160
gene id: 1631871:FOL01_RS03160
uniprot id: A0A1L6RAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1631871:FOL01 RS06680
gene id: 1631871:FOL01_RS06680
uniprot id: A0A1L6RC72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1631871:FOL01 RS00570
gene id: 1631871:FOL01_RS00570
uniprot id: A0A1L6R8T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1631871:FOL01 RS10550
gene id: 1631871:FOL01_RS10550
uniprot id: A0A1L6RE86
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS05055
gene id: 1631871:FOL01_RS05055
uniprot id: A0A1L6RBG8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1631871:FOL01 RS09000
gene id: 1631871:FOL01_RS09000
uniprot id: A0A1L6RDI0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1631871:FOL01 RS10160
gene id: 1631871:FOL01_RS10160
uniprot id: A0A1L6RE10
names: Similarity
messages: Belongs to the CapA family.

1631871:FOL01 RS09915
gene id: 1631871:FOL01_RS09915
uniprot id: A0A1L6RDZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1631871:FOL01 RS06030
gene id: 1631871:FOL01_RS06030
uniprot id: A0A1L6RBZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1631871:FOL01 RS03330
gene id: 1631871:FOL01_RS03330
uniprot id: A0A1L6RAA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1631871:FOL01 RS09715
gene id: 1631871:FOL01_RS09715
uniprot id: A0A1L6RDR4
names: Similarity
messages: Belongs to the asparaginase 1 family.

1631871:FOL01 RS04070
gene id: 1631871:FOL01_RS04070
uniprot id: A0A1L6RAN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1631871:FOL01 RS08925
gene id: 1631871:FOL01_RS08925
uniprot id: A0A1L6RDN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1631871:FOL01 RS09090
gene id: 1631871:FOL01_RS09090
uniprot id: A0A1L6RDF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

1631871:FOL01 RS09925
gene id: 1631871:FOL01_RS09925
uniprot id: A0A1L6RE32
names: Similarity
messages: Belongs to the acylphosphatase family.

1631871:FOL01 RS02000
gene id: 1631871:FOL01_RS02000
uniprot id: A0A1L6R9K3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1631871:FOL01 RS09265
gene id: 1631871:FOL01_RS09265
uniprot id: A0A1L6RDI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1631871:FOL01 RS06500
gene id: 1631871:FOL01_RS06500
uniprot id: A0A1L6RCA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

1631871:FOL01 RS04375
gene id: 1631871:FOL01_RS04375
uniprot id: A0A1L6RAU3
names: Similarity
messages: Belongs to the CFA/CMAS family.

1631871:FOL01 RS03425
gene id: 1631871:FOL01_RS03425
uniprot id: A0A1L6RAE0
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS05785
gene id: 1631871:FOL01_RS05785
uniprot id: A0A1L6RBV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1631871:FOL01 RS02050
gene id: 1631871:FOL01_RS02050
uniprot id: A0A1L6R9L2
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS02010
gene id: 1631871:FOL01_RS02010
uniprot id: A0A1L6R9K1
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS02835
gene id: 1631871:FOL01_RS02835
uniprot id: A0A1L6RA01
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1631871:FOL01 RS04010
gene id: 1631871:FOL01_RS04010
uniprot id: A0A1L6RAP6
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS01905
gene id: 1631871:FOL01_RS01905
uniprot id: A0A1L6R9N4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1631871:FOL01 RS09875
gene id: 1631871:FOL01_RS09875
uniprot id: A0A1L6RE25
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.

1631871:FOL01 RS08190
gene id: 1631871:FOL01_RS08190
uniprot id: A0A1L6RD13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1631871:FOL01 RS04395
gene id: 1631871:FOL01_RS04395
uniprot id: A0A1L6RAV6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS08555
gene id: 1631871:FOL01_RS08555
uniprot id: A0A1L6RDD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS02630
gene id: 1631871:FOL01_RS02630
uniprot id: A0A1L6R9X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1631871:FOL01 RS03315
gene id: 1631871:FOL01_RS03315
uniprot id: A0A1L6RAD2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1631871:FOL01 RS03365
gene id: 1631871:FOL01_RS03365
uniprot id: A0A1L6RAF0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1631871:FOL01 RS03410
gene id: 1631871:FOL01_RS03410
uniprot id: A0A1L6RAI6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1631871:FOL01 RS08430
gene id: 1631871:FOL01_RS08430
uniprot id: A0A1L6RD60
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1631871:FOL01 RS04740
gene id: 1631871:FOL01_RS04740
uniprot id: A0A1L6RBB5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1631871:FOL01 RS03175
gene id: 1631871:FOL01_RS03175
uniprot id: A0A1L6RA88
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS07235
gene id: 1631871:FOL01_RS07235
uniprot id: A0A1L6RCN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1631871:FOL01 RS02075
gene id: 1631871:FOL01_RS02075
uniprot id: A0A1L6R9R8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1631871:FOL01 RS07170
gene id: 1631871:FOL01_RS07170
uniprot id: A0A1L6RCF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1631871:FOL01 RS07705
gene id: 1631871:FOL01_RS07705
uniprot id: A0A1L6RCR4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1631871:FOL01 RS03560
gene id: 1631871:FOL01_RS03560
uniprot id: A0A1L6RAI0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS09695
gene id: 1631871:FOL01_RS09695
uniprot id: A0A1L6RDZ3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

1631871:FOL01 RS00220
gene id: 1631871:FOL01_RS00220
uniprot id: A0A1L6R8R8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1631871:FOL01 RS07950
gene id: 1631871:FOL01_RS07950
uniprot id: A0A1L6RD38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1631871:FOL01 RS07430
gene id: 1631871:FOL01_RS07430
uniprot id: A0A1L6RCK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1631871:FOL01 RS06695
gene id: 1631871:FOL01_RS06695
uniprot id: A0A1L6RC66
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1631871:FOL01 RS10470
gene id: 1631871:FOL01_RS10470
uniprot id: A0A1L6REG1
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS03735
gene id: 1631871:FOL01_RS03735
uniprot id: A0A1L6RAN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1631871:FOL01 RS04045
gene id: 1631871:FOL01_RS04045
uniprot id: A0A1L6RAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1631871:FOL01 RS03275
gene id: 1631871:FOL01_RS03275
uniprot id: A0A1L6RAB2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1631871:FOL01 RS01565
gene id: 1631871:FOL01_RS01565
uniprot id: A0A1L6R9C6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1631871:FOL01 RS04170
gene id: 1631871:FOL01_RS04170
uniprot id: A0A1L6RAP9
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS06780
gene id: 1631871:FOL01_RS06780
uniprot id: A0A1L6RCD4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1631871:FOL01 RS07755
gene id: 1631871:FOL01_RS07755
uniprot id: A0A1L6RCS3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS03430
gene id: 1631871:FOL01_RS03430
uniprot id: A0A1L6RAC6
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS01255
gene id: 1631871:FOL01_RS01255
uniprot id: A0A1L6R965
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS09245
gene id: 1631871:FOL01_RS09245
uniprot id: A0A1L6RDR3
names: Similarity
messages: Belongs to the DCK/DGK family.

1631871:FOL01 RS07230
gene id: 1631871:FOL01_RS07230
uniprot id: A0A1L6RCG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1631871:FOL01 RS09865
gene id: 1631871:FOL01_RS09865
uniprot id: A0A1L6RDY5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1631871:FOL01 RS00005
gene id: 1631871:FOL01_RS00005
uniprot id: A0A1L6R8M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1631871:FOL01 RS00370
gene id: 1631871:FOL01_RS00370
uniprot id: A0A1L6R8U9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1631871:FOL01 RS06675
gene id: 1631871:FOL01_RS06675
uniprot id: A0A1L6RCD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS10305
gene id: 1631871:FOL01_RS10305
uniprot id: A0A1L6REB4
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1631871:FOL01 RS06090
gene id: 1631871:FOL01_RS06090
uniprot id: A0A1L6RC27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1631871:FOL01 RS10230
gene id: 1631871:FOL01_RS10230
uniprot id: A0A1L6REC1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

1631871:FOL01 RS02805
gene id: 1631871:FOL01_RS02805
uniprot id: A0A1L6RA07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1631871:FOL01 RS07275
gene id: 1631871:FOL01_RS07275
uniprot id: A0A1L6RCH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1631871:FOL01 RS06290
gene id: 1631871:FOL01_RS06290
uniprot id: A0A1L6RBZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1631871:FOL01 RS09290
gene id: 1631871:FOL01_RS09290
uniprot id: A0A1L6RDJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1631871:FOL01 RS04990
gene id: 1631871:FOL01_RS04990
uniprot id: A0A1L6RB70
names: Similarity
messages: Belongs to the UPF0045 family.

1631871:FOL01 RS03390
gene id: 1631871:FOL01_RS03390
uniprot id: A0A1L6RAG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1631871:FOL01 RS03925
gene id: 1631871:FOL01_RS03925
uniprot id: A0A1L6RAK1
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1631871:FOL01 RS08810
gene id: 1631871:FOL01_RS08810
uniprot id: A0A1L6RDA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1631871:FOL01 RS07445
gene id: 1631871:FOL01_RS07445
uniprot id: A0A1L6RCU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS10190
gene id: 1631871:FOL01_RS10190
uniprot id: A0A1L6RE37
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1631871:FOL01 RS05010
gene id: 1631871:FOL01_RS05010
uniprot id: A0A1L6RBB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS00535
gene id: 1631871:FOL01_RS00535
uniprot id: A0A1L6R8Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1631871:FOL01 RS09900
gene id: 1631871:FOL01_RS09900
uniprot id: A0A1L6RDY0
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS03370
gene id: 1631871:FOL01_RS03370
uniprot id: A0A1L6RAC5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1631871:FOL01 RS03525
gene id: 1631871:FOL01_RS03525
uniprot id: A0A1L6RAE2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1631871:FOL01 RS02525
gene id: 1631871:FOL01_RS02525
uniprot id: A0A1L6R9X8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1631871:FOL01 RS03395
gene id: 1631871:FOL01_RS03395
uniprot id: A0A1L6RAB3
names: Similarity
messages: Belongs to the DapB family.

1631871:FOL01 RS02590
gene id: 1631871:FOL01_RS02590
uniprot id: A0A1L6R9W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1631871:FOL01 RS01295
gene id: 1631871:FOL01_RS01295
uniprot id: A0A1L6R9A1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1631871:FOL01 RS04075
gene id: 1631871:FOL01_RS04075
uniprot id: A0A1L6RAV3
names: Similarity
messages: Belongs to the RecJ family.

1631871:FOL01 RS06620
gene id: 1631871:FOL01_RS06620
uniprot id: A0A1L6RC49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1631871:FOL01 RS09910
gene id: 1631871:FOL01_RS09910
uniprot id: A0A1L6RDY3
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family.

1631871:FOL01 RS04140
gene id: 1631871:FOL01_RS04140
uniprot id: A0A1L6RAR2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1631871:FOL01 RS04120
gene id: 1631871:FOL01_RS04120
uniprot id: A0A1L6RAP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS08965
gene id: 1631871:FOL01_RS08965
uniprot id: A0A1L6RDD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1631871:FOL01 RS09210
gene id: 1631871:FOL01_RS09210
uniprot id: A0A1L6RDH6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1631871:FOL01 RS06670
gene id: 1631871:FOL01_RS06670
uniprot id: A0A1L6RC58
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS09300
gene id: 1631871:FOL01_RS09300
uniprot id: A0A1L6RDM0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1631871:FOL01 RS06320
gene id: 1631871:FOL01_RS06320
uniprot id: A0A1L6RBY7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1631871:FOL01 RS06060
gene id: 1631871:FOL01_RS06060
uniprot id: A0A1L6RBU7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1631871:FOL01 RS02420
gene id: 1631871:FOL01_RS02420
uniprot id: A0A1L6R9X1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1631871:FOL01 RS10435
gene id: 1631871:FOL01_RS10435
uniprot id: A0A1L6RE91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1631871:FOL01 RS10355
gene id: 1631871:FOL01_RS10355
uniprot id: A0A1L6RE45
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1631871:FOL01 RS05100
gene id: 1631871:FOL01_RS05100
uniprot id: A0A1L6RBH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1631871:FOL01 RS03205
gene id: 1631871:FOL01_RS03205
uniprot id: A0A1L6RA71
names: Similarity
messages: Belongs to the CarB family.

1631871:FOL01 RS06010
gene id: 1631871:FOL01_RS06010
uniprot id: A0A1L6RBW1
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1631871:FOL01 RS08340
gene id: 1631871:FOL01_RS08340
uniprot id: A0A1L6RD91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1631871:FOL01 RS02700
gene id: 1631871:FOL01_RS02700
uniprot id: A0A1L6RA41
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1631871:FOL01 RS07270
gene id: 1631871:FOL01_RS07270
uniprot id: A0A1L6RCN6
names: Similarity
messages: Belongs to the GSP E family.

1631871:FOL01 RS09800
gene id: 1631871:FOL01_RS09800
uniprot id: A0A1L6RDW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1631871:FOL01 RS03070
gene id: 1631871:FOL01_RS03070
uniprot id: A0A1L6RA60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS08030
gene id: 1631871:FOL01_RS08030
uniprot id: A0A1L6RD27
names: Similarity
messages: Belongs to the isochorismate synthase family.

1631871:FOL01 RS09835
gene id: 1631871:FOL01_RS09835
uniprot id: A0A1L6RE24
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS05295
gene id: 1631871:FOL01_RS05295
uniprot id: A0A1L6RBD7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1631871:FOL01 RS05950
gene id: 1631871:FOL01_RS05950
uniprot id: A0A1L6RBZ6
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS10320
gene id: 1631871:FOL01_RS10320
uniprot id: A0A1L6RE66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1631871:FOL01 RS00185
gene id: 1631871:FOL01_RS00185
uniprot id: A0A1L6R8L9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1631871:FOL01 RS01195
gene id: 1631871:FOL01_RS01195
uniprot id: A0A1L6R981
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

1631871:FOL01 RS03455
gene id: 1631871:FOL01_RS03455
uniprot id: A0A1L6RAB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1631871:FOL01 RS01570
gene id: 1631871:FOL01_RS01570
uniprot id: A0A1L6R9C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1631871:FOL01 RS06635
gene id: 1631871:FOL01_RS06635
uniprot id: A0A1L6RCD3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1631871:FOL01 RS04535
gene id: 1631871:FOL01_RS04535
uniprot id: A0A1L6RB71
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS05240
gene id: 1631871:FOL01_RS05240
uniprot id: A0A1L6RBJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1631871:FOL01 RS03580
gene id: 1631871:FOL01_RS03580
uniprot id: A0A1L6RAD7
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1631871:FOL01 RS06225
gene id: 1631871:FOL01_RS06225
uniprot id: A0A1L6RC34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1631871:FOL01 RS04475
gene id: 1631871:FOL01_RS04475
uniprot id: A0A1L6RAW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS10750
gene id: 1631871:FOL01_RS10750
uniprot id: A0A1L6REH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1631871:FOL01 RS06125
gene id: 1631871:FOL01_RS06125
uniprot id: A0A1L6RBU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1631871:FOL01 RS07490
gene id: 1631871:FOL01_RS07490
uniprot id: A0A1L6RCQ0
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

1631871:FOL01 RS03605
gene id: 1631871:FOL01_RS03605
uniprot id: A0A1L6RAM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1631871:FOL01 RS08775
gene id: 1631871:FOL01_RS08775
uniprot id: A0A1L6RDB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1631871:FOL01 RS04625
gene id: 1631871:FOL01_RS04625
uniprot id: A0A1L6RB76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1631871:FOL01 RS10165
gene id: 1631871:FOL01_RS10165
uniprot id: A0A1L6RE88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1631871:FOL01 RS09535
gene id: 1631871:FOL01_RS09535
uniprot id: A0A1L6RDQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS02865
gene id: 1631871:FOL01_RS02865
uniprot id: A0A1L6RA53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1631871:FOL01 RS04175
gene id: 1631871:FOL01_RS04175
uniprot id: A0A1L6RAY1
names: Similarity
messages: Belongs to the MYG1 family.

1631871:FOL01 RS02775
gene id: 1631871:FOL01_RS02775
uniprot id: A0A1L6RA23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1631871:FOL01 RS05810
gene id: 1631871:FOL01_RS05810
uniprot id: A0A1L6RBX0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1631871:FOL01 RS09955
gene id: 1631871:FOL01_RS09955
uniprot id: A0A1L6RDW4
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.

1631871:FOL01 RS03200
gene id: 1631871:FOL01_RS03200
uniprot id: A0A1L6RAE5
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS06280
gene id: 1631871:FOL01_RS06280
uniprot id: A0A1L6RBY5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1631871:FOL01 RS06265
gene id: 1631871:FOL01_RS06265
uniprot id: A0A1L6RC14
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1631871:FOL01 RS09820
gene id: 1631871:FOL01_RS09820
uniprot id: A0A1L6RDT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS06985
gene id: 1631871:FOL01_RS06985
uniprot id: A0A1L6RCD9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS08630
gene id: 1631871:FOL01_RS08630
uniprot id: A0A1L6RD93
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1631871:FOL01 RS04380
gene id: 1631871:FOL01_RS04380
uniprot id: A0A1L6RB28
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS08520
gene id: 1631871:FOL01_RS08520
uniprot id: A0A1L6RD69
names: Similarity
messages: Belongs to the TrpC family.

1631871:FOL01 RS01820
gene id: 1631871:FOL01_RS01820
uniprot id: A0A1L6R9K5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1631871:FOL01 RS09215
gene id: 1631871:FOL01_RS09215
uniprot id: A0A1L6RDP4
names: Similarity
messages: Belongs to the CtsR family.

1631871:FOL01 RS06145
gene id: 1631871:FOL01_RS06145
uniprot id: A0A1L6RBW8
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1631871:FOL01 RS06625
gene id: 1631871:FOL01_RS06625
uniprot id: A0A1L6RCC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1631871:FOL01 RS07365
gene id: 1631871:FOL01_RS07365
uniprot id: A0A1L6RCJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1631871:FOL01 RS01970
gene id: 1631871:FOL01_RS01970
uniprot id: A0A1L6R9N6
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS01475
gene id: 1631871:FOL01_RS01475
uniprot id: A0A1L6R9A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1631871:FOL01 RS01010
gene id: 1631871:FOL01_RS01010
uniprot id: A0A1L6R924
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1631871:FOL01 RS07205
gene id: 1631871:FOL01_RS07205
uniprot id: A0A1L6RCF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1631871:FOL01 RS02040
gene id: 1631871:FOL01_RS02040
uniprot id: A0A1L6R9P7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1631871:FOL01 RS07860
gene id: 1631871:FOL01_RS07860
uniprot id: A0A1L6RCR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1631871:FOL01 RS10150
gene id: 1631871:FOL01_RS10150
uniprot id: A0A1L6RE31
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS05840
gene id: 1631871:FOL01_RS05840
uniprot id: A0A1L6RBS0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1631871:FOL01 RS07165
gene id: 1631871:FOL01_RS07165
uniprot id: A0A1L6RCI1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1631871:FOL01 RS05125
gene id: 1631871:FOL01_RS05125
uniprot id: A0A1L6RBC4
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

1631871:FOL01 RS06560
gene id: 1631871:FOL01_RS06560
uniprot id: A0A1L6RC26
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1631871:FOL01 RS02025
gene id: 1631871:FOL01_RS02025
uniprot id: A0A1L6R9Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1631871:FOL01 RS08585
gene id: 1631871:FOL01_RS08585
uniprot id: A0A1L6RD92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS06140
gene id: 1631871:FOL01_RS06140
uniprot id: A0A1L6RC37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1631871:FOL01 RS04345
gene id: 1631871:FOL01_RS04345
uniprot id: A0A1L6RB24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1631871:FOL01 RS00025
gene id: 1631871:FOL01_RS00025
uniprot id: A0A1L6R8I7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1631871:FOL01 RS09120
gene id: 1631871:FOL01_RS09120
uniprot id: A0A1L6RDP6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1631871:FOL01 RS07580
gene id: 1631871:FOL01_RS07580
uniprot id: A0A1L6RCN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1631871:FOL01 RS04975
gene id: 1631871:FOL01_RS04975
uniprot id: A0A1L6RB98
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1631871:FOL01 RS01020
gene id: 1631871:FOL01_RS01020
uniprot id: A0A1L6R970
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS09330
gene id: 1631871:FOL01_RS09330
uniprot id: A0A1L6RDJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1631871:FOL01 RS07795
gene id: 1631871:FOL01_RS07795
uniprot id: A0A1L6RCT5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1631871:FOL01 RS03270
gene id: 1631871:FOL01_RS03270
uniprot id: A0A1L6RAA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1631871:FOL01 RS04190
gene id: 1631871:FOL01_RS04190
uniprot id: A0A1L6RAR9
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1631871:FOL01 RS10625
gene id: 1631871:FOL01_RS10625
uniprot id: A0A1L6REC4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1631871:FOL01 RS07395
gene id: 1631871:FOL01_RS07395
uniprot id: A0A1L6RCT4
names: Similarity
messages: Belongs to the pyruvate kinase family.

1631871:FOL01 RS09685
gene id: 1631871:FOL01_RS09685
uniprot id: A0A1L6RDY2
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS01760
gene id: 1631871:FOL01_RS01760
uniprot id: A0A1L6R9G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS09055
gene id: 1631871:FOL01_RS09055
uniprot id: A0A1L6RDE3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1631871:FOL01 RS02800
gene id: 1631871:FOL01_RS02800
uniprot id: A0A1L6RA66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1631871:FOL01 RS02975
gene id: 1631871:FOL01_RS02975
uniprot id: A0A1L6RA15
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS10120
gene id: 1631871:FOL01_RS10120
uniprot id: A0A1L6RDZ9
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1631871:FOL01 RS09495
gene id: 1631871:FOL01_RS09495
uniprot id: A0A1L6RDS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1631871:FOL01 RS00935
gene id: 1631871:FOL01_RS00935
uniprot id: A0A1L6R943
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1631871:FOL01 RS10485
gene id: 1631871:FOL01_RS10485
uniprot id: A0A1L6RE99
names: Subcellular Location Annotation
messages: cell wall

1631871:FOL01 RS01955
gene id: 1631871:FOL01_RS01955
uniprot id: A0A1L6R9P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1631871:FOL01 RS04050
gene id: 1631871:FOL01_RS04050
uniprot id: A0A1L6RAS7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1631871:FOL01 RS07100
gene id: 1631871:FOL01_RS07100
uniprot id: A0A1L6RCG5
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1631871:FOL01 RS09285
gene id: 1631871:FOL01_RS09285
uniprot id: A0A1L6RDQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1631871:FOL01 RS06585
gene id: 1631871:FOL01_RS06585
uniprot id: A0A1L6RCC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0213 family.
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1631871:FOL01 RS04405
gene id: 1631871:FOL01_RS04405
uniprot id: A0A1L6RAZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

1631871:FOL01 RS01895
gene id: 1631871:FOL01_RS01895
uniprot id: A0A1L6R9M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1631871:FOL01 RS07725
gene id: 1631871:FOL01_RS07725
uniprot id: A0A1L6RCP0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1631871:FOL01 RS04295
gene id: 1631871:FOL01_RS04295
uniprot id: A0A1L6RB14
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1631871:FOL01 RS04355
gene id: 1631871:FOL01_RS04355
uniprot id: A0A1L6RAX0
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1631871:FOL01 RS06575
gene id: 1631871:FOL01_RS06575
uniprot id: A0A1L6RCB2
names: Similarity
messages: Belongs to the IMPACT family.

1631871:FOL01 RS06110
gene id: 1631871:FOL01_RS06110
uniprot id: A0A1L6RBV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1631871:FOL01 RS05325
gene id: 1631871:FOL01_RS05325
uniprot id: A0A1L6RBG0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1631871:FOL01 RS02735
gene id: 1631871:FOL01_RS02735
uniprot id: A0A1L6R9Y2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1631871:FOL01 RS06750
gene id: 1631871:FOL01_RS06750
uniprot id: A0A1L6RCF5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1631871:FOL01 RS00440
gene id: 1631871:FOL01_RS00440
uniprot id: A0A1L6R8X6
names: Similarity
messages: Belongs to the LOG family.

1631871:FOL01 RS03385
gene id: 1631871:FOL01_RS03385
uniprot id: A0A1L6RAA0
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
messages: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.

1631871:FOL01 RS03130
gene id: 1631871:FOL01_RS03130
uniprot id: A0A1L6RA73
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1631871:FOL01 RS03485
gene id: 1631871:FOL01_RS03485
uniprot id: A0A1L6RAB9
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS06520
gene id: 1631871:FOL01_RS06520
uniprot id: A0A1L6RC32
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS03460
gene id: 1631871:FOL01_RS03460
uniprot id: A0A1L6RAI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1631871:FOL01 RS03725
gene id: 1631871:FOL01_RS03725
uniprot id: A0A1L6RAK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1631871:FOL01 RS09270
gene id: 1631871:FOL01_RS09270
uniprot id: A0A1L6RDL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1631871:FOL01 RS01815
gene id: 1631871:FOL01_RS01815
uniprot id: A0A1L6R9L9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1631871:FOL01 RS09305
gene id: 1631871:FOL01_RS09305
uniprot id: A0A1L6RDU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS01200
gene id: 1631871:FOL01_RS01200
uniprot id: A0A1L6R954
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1631871:FOL01 RS02095
gene id: 1631871:FOL01_RS02095
uniprot id: A0A1L6R9M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1631871:FOL01 RS03435
gene id: 1631871:FOL01_RS03435
uniprot id: A0A1L6RAB1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS00985
gene id: 1631871:FOL01_RS00985
uniprot id: A0A1L6R926
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1631871:FOL01 RS07745
gene id: 1631871:FOL01_RS07745
uniprot id: A0A1L6RCS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1631871:FOL01 RS09730
gene id: 1631871:FOL01_RS09730
uniprot id: A0A1L6RDR5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1631871:FOL01 RS02970
gene id: 1631871:FOL01_RS02970
uniprot id: A0A1L6RA39
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS07875
gene id: 1631871:FOL01_RS07875
uniprot id: A0A1L6RCR7
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1631871:FOL01 RS09825
gene id: 1631871:FOL01_RS09825
uniprot id: A0A1L6RE12
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1631871:FOL01 RS08940
gene id: 1631871:FOL01_RS08940
uniprot id: A0A1L6RDC3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1631871:FOL01 RS02665
gene id: 1631871:FOL01_RS02665
uniprot id: A0A1L6RA18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1631871:FOL01 RS05310
gene id: 1631871:FOL01_RS05310
uniprot id: A0A1L6RBL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1631871:FOL01 RS03785
gene id: 1631871:FOL01_RS03785
uniprot id: A0A1L6RAP7
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS02815
gene id: 1631871:FOL01_RS02815
uniprot id: A0A1L6RA44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS04755
gene id: 1631871:FOL01_RS04755
uniprot id: A0A1L6RB63
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1631871:FOL01 RS03930
gene id: 1631871:FOL01_RS03930
uniprot id: A0A1L6RAS3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1631871:FOL01 RS08745
gene id: 1631871:FOL01_RS08745
uniprot id: A0A1L6RD74
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1631871:FOL01 RS07090
gene id: 1631871:FOL01_RS07090
uniprot id: A0A1L6RCF7
names: Similarity
messages: Belongs to the peptidase C40 family.

1631871:FOL01 RS08920
gene id: 1631871:FOL01_RS08920
uniprot id: A0A1L6RDE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1631871:FOL01 RS08290
gene id: 1631871:FOL01_RS08290
uniprot id: A0A1L6RD82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1631871:FOL01 RS09415
gene id: 1631871:FOL01_RS09415
uniprot id: A0A1L6RDU3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1631871:FOL01 RS09125
gene id: 1631871:FOL01_RS09125
uniprot id: A0A1L6RDI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1631871:FOL01 RS04445
gene id: 1631871:FOL01_RS04445
uniprot id: A0A1L6RAW6
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

1631871:FOL01 RS06270
gene id: 1631871:FOL01_RS06270
uniprot id: A0A1L6RBX7
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1631871:FOL01 RS10270
gene id: 1631871:FOL01_RS10270
uniprot id: A0A1L6REB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS09430
gene id: 1631871:FOL01_RS09430
uniprot id: A0A1L6RDN7
names: Similarity
messages: Belongs to the XFP family.

1631871:FOL01 RS02740
gene id: 1631871:FOL01_RS02740
uniprot id: A0A1L6RA48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1631871:FOL01 RS06305
gene id: 1631871:FOL01_RS06305
uniprot id: A0A1L6RBZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1631871:FOL01 RS08285
gene id: 1631871:FOL01_RS08285
uniprot id: A0A1L6RD01
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1631871:FOL01 RS10495
gene id: 1631871:FOL01_RS10495
uniprot id: A0A1L6RE78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1631871:FOL01 RS04160
gene id: 1631871:FOL01_RS04160
uniprot id: A0A1L6RAT1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1631871:FOL01 RS08740
gene id: 1631871:FOL01_RS08740
uniprot id: A0A1L6RDC5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1631871:FOL01 RS06800
gene id: 1631871:FOL01_RS06800
uniprot id: A0A1L6RCG4
names: Similarity
messages: Belongs to the TelA family.

1631871:FOL01 RS00165
gene id: 1631871:FOL01_RS00165
uniprot id: A0A1L6R8M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1631871:FOL01 RS06490
gene id: 1631871:FOL01_RS06490
uniprot id: A0A1L6RC87
names: Similarity
messages: Belongs to the UPF0297 family.

1631871:FOL01 RS02995
gene id: 1631871:FOL01_RS02995
uniprot id: A0A1L6RA36
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1631871:FOL01 RS03620
gene id: 1631871:FOL01_RS03620
uniprot id: A0A1L6RAH4
names: Similarity
messages: Belongs to the UPF0342 family.

1631871:FOL01 RS04180
gene id: 1631871:FOL01_RS04180
uniprot id: A0A1L6RAS2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

1631871:FOL01 RS10480
gene id: 1631871:FOL01_RS10480
uniprot id: A0A1L6RE73
names: Subcellular Location Annotation
messages: cell wall

1631871:FOL01 RS02745
gene id: 1631871:FOL01_RS02745
uniprot id: A0A1L6R9Y4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1631871:FOL01 RS06135
gene id: 1631871:FOL01_RS06135
uniprot id: A0A1L6RBV7
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1631871:FOL01 RS04300
gene id: 1631871:FOL01_RS04300
uniprot id: A0A1L6RAX8
names: Similarity
messages: Belongs to the ThiD family.

1631871:FOL01 RS07175
gene id: 1631871:FOL01_RS07175
uniprot id: A0A1L6RCL4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1631871:FOL01 RS03610
gene id: 1631871:FOL01_RS03610
uniprot id: A0A1L6RAJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1631871:FOL01 RS06210
gene id: 1631871:FOL01_RS06210
uniprot id: A0A1L6RBZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1631871:FOL01 RS08900
gene id: 1631871:FOL01_RS08900
uniprot id: A0A1L6RDB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS02090
gene id: 1631871:FOL01_RS02090
uniprot id: A0A1L6R9Q5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1631871:FOL01 RS10140
gene id: 1631871:FOL01_RS10140
uniprot id: A0A1L6RE30
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1631871:FOL01 RS09470
gene id: 1631871:FOL01_RS09470
uniprot id: A0A1L6RDP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS00435
gene id: 1631871:FOL01_RS00435
uniprot id: A0A1L6R8S1
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1631871:FOL01 RS03570
gene id: 1631871:FOL01_RS03570
uniprot id: A0A1L6RAG9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1631871:FOL01 RS06665
gene id: 1631871:FOL01_RS06665
uniprot id: A0A1L6RCB4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1631871:FOL01 RS01865
gene id: 1631871:FOL01_RS01865
uniprot id: A0A1L6R9M9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS04575
gene id: 1631871:FOL01_RS04575
uniprot id: A0A1L6RAY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1631871:FOL01 RS03020
gene id: 1631871:FOL01_RS03020
uniprot id: A0A1L6RA50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS08815
gene id: 1631871:FOL01_RS08815
uniprot id: A0A1L6RDI5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS01420
gene id: 1631871:FOL01_RS01420
uniprot id: A0A1L6R9D3
names: Similarity
messages: Belongs to the UPF0735 family.

1631871:FOL01 RS08850
gene id: 1631871:FOL01_RS08850
uniprot id: A0A1L6RDA1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1631871:FOL01 RS10330
gene id: 1631871:FOL01_RS10330
uniprot id: A0A1L6RE67
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS02670
gene id: 1631871:FOL01_RS02670
uniprot id: A0A1L6R9Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1631871:FOL01 RS02870
gene id: 1631871:FOL01_RS02870
uniprot id: A0A1L6RA34
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1631871:FOL01 RS05155
gene id: 1631871:FOL01_RS05155
uniprot id: A0A1L6RBB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1631871:FOL01 RS07155
gene id: 1631871:FOL01_RS07155
uniprot id: A0A1L6RCE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1631871:FOL01 RS07300
gene id: 1631871:FOL01_RS07300
uniprot id: A0A1L6RCH7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1631871:FOL01 RS06445
gene id: 1631871:FOL01_RS06445
uniprot id: A0A1L6RC12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS09755
gene id: 1631871:FOL01_RS09755
uniprot id: A0A1L6RE22
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1631871:FOL01 RS08625
gene id: 1631871:FOL01_RS08625
uniprot id: A0A1L6RD61
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1631871:FOL01 RS02675
gene id: 1631871:FOL01_RS02675
uniprot id: A0A1L6RA05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1631871:FOL01 RS07140
gene id: 1631871:FOL01_RS07140
uniprot id: A0A1L6RCG9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1631871:FOL01 RS09030
gene id: 1631871:FOL01_RS09030
uniprot id: A0A1L6RDQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1631871:FOL01 RS03745
gene id: 1631871:FOL01_RS03745
uniprot id: A0A1L6RAR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS07225
gene id: 1631871:FOL01_RS07225
uniprot id: A0A1L6RCM3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1631871:FOL01 RS06495
gene id: 1631871:FOL01_RS06495
uniprot id: A0A1L6RC22
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS08440
gene id: 1631871:FOL01_RS08440
uniprot id: A0A1L6RD16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1631871:FOL01 RS08765
gene id: 1631871:FOL01_RS08765
uniprot id: A0A1L6RDB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1631871:FOL01 RS08515
gene id: 1631871:FOL01_RS08515
uniprot id: A0A1L6RDF1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS01210
gene id: 1631871:FOL01_RS01210
uniprot id: A0A1L6R995
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1631871:FOL01 RS01650
gene id: 1631871:FOL01_RS01650
uniprot id: A0A1L6R9I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS07160
gene id: 1631871:FOL01_RS07160
uniprot id: A0A1L6RCH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1631871:FOL01 RS10605
gene id: 1631871:FOL01_RS10605
uniprot id: A0A1L6REA2
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1631871:FOL01 RS04215
gene id: 1631871:FOL01_RS04215
uniprot id: A0A1L6RAU7
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1631871:FOL01 RS03585
gene id: 1631871:FOL01_RS03585
uniprot id: A0A1L6RAK5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1631871:FOL01 RS09065
gene id: 1631871:FOL01_RS09065
uniprot id: A0A1L6RDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1631871:FOL01 RS09660
gene id: 1631871:FOL01_RS09660
uniprot id: A0A1L6RDS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1631871:FOL01 RS04485
gene id: 1631871:FOL01_RS04485
uniprot id: A0A1L6RB62
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS10020
gene id: 1631871:FOL01_RS10020
uniprot id: A0A1L6RDX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1631871:FOL01 RS01040
gene id: 1631871:FOL01_RS01040
uniprot id: A0A1L6R979
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS09160
gene id: 1631871:FOL01_RS09160
uniprot id: A0A1L6RDG7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1631871:FOL01 RS10040
gene id: 1631871:FOL01_RS10040
uniprot id: A0A1L6RE85
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS03025
gene id: 1631871:FOL01_RS03025
uniprot id: A0A1L6RA25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1631871:FOL01 RS03505
gene id: 1631871:FOL01_RS03505
uniprot id: A0A1L6RAC8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1631871:FOL01 RS06550
gene id: 1631871:FOL01_RS06550
uniprot id: A0A1L6RC57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1631871:FOL01 RS00270
gene id: 1631871:FOL01_RS00270
uniprot id: A0A1L6R8S9
names: Similarity
messages: Belongs to the Dps family.

1631871:FOL01 RS01780
gene id: 1631871:FOL01_RS01780
uniprot id: A0A1L6R9J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS01585
gene id: 1631871:FOL01_RS01585
uniprot id: A0A1L6R9H2
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1631871:FOL01 RS03565
gene id: 1631871:FOL01_RS03565
uniprot id: A0A1L6RAG3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1631871:FOL01 RS03800
gene id: 1631871:FOL01_RS03800
uniprot id: A0A1L6RAI5
names: Similarity
messages: Belongs to the UPF0145 family.

1631871:FOL01 RS10185
gene id: 1631871:FOL01_RS10185
uniprot id: A0A1L6REB0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1631871:FOL01 RS08550
gene id: 1631871:FOL01_RS08550
uniprot id: A0A1L6RD54
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1631871:FOL01 RS07185
gene id: 1631871:FOL01_RS07185
uniprot id: A0A1L6RCM5
names: Similarity
messages: Belongs to the asp23 family.

1631871:FOL01 RS01590
gene id: 1631871:FOL01_RS01590
uniprot id: A0A1L6R9D5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1631871:FOL01 RS03450
gene id: 1631871:FOL01_RS03450
uniprot id: A0A1L6RAK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1631871:FOL01 RS07145
gene id: 1631871:FOL01_RS07145
uniprot id: A0A1L6RCN4
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1631871:FOL01 RS10255
gene id: 1631871:FOL01_RS10255
uniprot id: A0A1L6RE28
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1631871:FOL01 RS07200
gene id: 1631871:FOL01_RS07200
uniprot id: A0A1L6RCI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1631871:FOL01 RS04590
gene id: 1631871:FOL01_RS04590
uniprot id: A0A1L6RB82
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the N-terminal section; belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

1631871:FOL01 RS01840
gene id: 1631871:FOL01_RS01840
uniprot id: A0A1L6R9H5
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS07470
gene id: 1631871:FOL01_RS07470
uniprot id: A0A1L6RCL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1631871:FOL01 RS06430
gene id: 1631871:FOL01_RS06430
uniprot id: A0A1L6RC43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1631871:FOL01 RS09140
gene id: 1631871:FOL01_RS09140
uniprot id: A0A1L6RDI8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1631871:FOL01 RS09275
gene id: 1631871:FOL01_RS09275
uniprot id: A0A1L6RDM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1631871:FOL01 RS04970
gene id: 1631871:FOL01_RS04970
uniprot id: A0A1L6RB94
names: Subcellular Location Annotation
messages: Cell membrane

1631871:FOL01 RS07735
gene id: 1631871:FOL01_RS07735
uniprot id: A0A1L6RCP4
names: Similarity
messages: Belongs to the TlyA family.

1631871:FOL01 RS00045
gene id: 1631871:FOL01_RS00045
uniprot id: A0A1L6R8P2
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.

1631871:FOL01 RS03265
gene id: 1631871:FOL01_RS03265
uniprot id: A0A1L6RAC3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1631871:FOL01 RS08915
gene id: 1631871:FOL01_RS08915
uniprot id: A0A1L6RDK3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1631871:FOL01 RS07945
gene id: 1631871:FOL01_RS07945
uniprot id: A0A1L6RCW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1631871:FOL01 RS05025
gene id: 1631871:FOL01_RS05025
uniprot id: A0A1L6RBA8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS01015
gene id: 1631871:FOL01_RS01015
uniprot id: A0A1L6R927
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1631871:FOL01 RS03225
gene id: 1631871:FOL01_RS03225
uniprot id: A0A1L6RA99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1631871:FOL01 RS00090
gene id: 1631871:FOL01_RS00090
uniprot id: A0A1L6R8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS05990
gene id: 1631871:FOL01_RS05990
uniprot id: A0A1L6RBY8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1631871:FOL01 RS02245
gene id: 1631871:FOL01_RS02245
uniprot id: A0A1L6R9P5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS10720
gene id: 1631871:FOL01_RS10720
uniprot id: A0A1L6REJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1631871:FOL01 RS01440
gene id: 1631871:FOL01_RS01440
uniprot id: A0A1L6R9E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1631871:FOL01 RS02220
gene id: 1631871:FOL01_RS02220
uniprot id: A0A1L6R9N0
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS06075
gene id: 1631871:FOL01_RS06075
uniprot id: A0A1L6RBT7
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1631871:FOL01 RS08725
gene id: 1631871:FOL01_RS08725
uniprot id: A0A1L6RDA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1631871:FOL01 RS05215
gene id: 1631871:FOL01_RS05215
uniprot id: A0A1L6R943
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1631871:FOL01 RS00200
gene id: 1631871:FOL01_RS00200
uniprot id: A0A1L6R8N0
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1631871:FOL01 RS06340
gene id: 1631871:FOL01_RS06340
uniprot id: A0A1L6RC09
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1631871:FOL01 RS08025
gene id: 1631871:FOL01_RS08025
uniprot id: A0A1L6RCU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1631871:FOL01 RS04795
gene id: 1631871:FOL01_RS04795
uniprot id: A0A1L6RB46
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1631871:FOL01 RS07890
gene id: 1631871:FOL01_RS07890
uniprot id: A0A1L6RD06
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS10195
gene id: 1631871:FOL01_RS10195
uniprot id: A0A1L6RE13
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1631871:FOL01 RS08265
gene id: 1631871:FOL01_RS08265
uniprot id: A0A1L6RD23
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1631871:FOL01 RS05075
gene id: 1631871:FOL01_RS05075
uniprot id: A0A1L6RBB9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1631871:FOL01 RS09130
gene id: 1631871:FOL01_RS09130
uniprot id: A0A1L6RDR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1631871:FOL01 RS10350
gene id: 1631871:FOL01_RS10350
uniprot id: A0A1L6REC2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1631871:FOL01 RS03770
gene id: 1631871:FOL01_RS03770
uniprot id: A0A1L6RAK2
names: Similarity
messages: Belongs to the peptidase M29 family.

1631871:FOL01 RS05650
gene id: 1631871:FOL01_RS05650
uniprot id: A0A1L6RBT2
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

1631871:FOL01 RS00340
gene id: 1631871:FOL01_RS00340
uniprot id: A0A1L6R8V1
names: Similarity
messages: Belongs to the PRORSD1 family.

1631871:FOL01 RS02880
gene id: 1631871:FOL01_RS02880
uniprot id: A0A1L6RA30
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1631871:FOL01 RS10275
gene id: 1631871:FOL01_RS10275
uniprot id: A0A1L6RE57
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1631871:FOL01 RS08845
gene id: 1631871:FOL01_RS08845
uniprot id: A0A1L6RDE8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1631871:FOL01 RS04510
gene id: 1631871:FOL01_RS04510
uniprot id: A0A1L6RB00
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1631871:FOL01 RS06400
gene id: 1631871:FOL01_RS06400
uniprot id: A0A1L6RC25
names: Similarity
messages: Belongs to the thioredoxin family.

1631871:FOL01 RS07360
gene id: 1631871:FOL01_RS07360
uniprot id: A0A1L6RCM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1631871:FOL01 RS08175
gene id: 1631871:FOL01_RS08175
uniprot id: A0A1L6RD53
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1631871:FOL01 RS06645
gene id: 1631871:FOL01_RS06645
uniprot id: A0A1L6RC56
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1631871:FOL01 RS08595
gene id: 1631871:FOL01_RS08595
uniprot id: A0A1L6RDC8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1631871:FOL01 RS02165
gene id: 1631871:FOL01_RS02165
uniprot id: A0A1L6R9S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1631871:FOL01 RS04040
gene id: 1631871:FOL01_RS04040
uniprot id: A0A1L6RAP1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1631871:FOL01 RS00010
gene id: 1631871:FOL01_RS00010
uniprot id: A0A1L6R8J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1631871:FOL01 RS04580
gene id: 1631871:FOL01_RS04580
uniprot id: A0A1L6RB67
names: Similarity
messages: Belongs to the UPF0246 family.

1631871:FOL01 RS02255
gene id: 1631871:FOL01_RS02255
uniprot id: A0A1L6R9P1
names: Similarity
messages: Belongs to the peptidase C1 family.

1631871:FOL01 RS07715
gene id: 1631871:FOL01_RS07715
uniprot id: A0A1L6RCS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1631871:FOL01 RS03970
gene id: 1631871:FOL01_RS03970
uniprot id: A0A1L6RAQ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1631871:FOL01 RS00540
gene id: 1631871:FOL01_RS00540
uniprot id: A0A1L6R8X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1631871:FOL01 RS06435
gene id: 1631871:FOL01_RS06435
uniprot id: A0A1L6RC04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1631871:FOL01 RS07435
gene id: 1631871:FOL01_RS07435
uniprot id: A0A1L6RCS8
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1631871:FOL01 RS07730
gene id: 1631871:FOL01_RS07730
uniprot id: A0A1L6RCW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1631871:FOL01 RS01455
gene id: 1631871:FOL01_RS01455
uniprot id: A0A1L6R9D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1631871:FOL01 RS09360
gene id: 1631871:FOL01_RS09360
uniprot id: A0A1L6RDN0
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS06580
gene id: 1631871:FOL01_RS06580
uniprot id: A0A1L6RC51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1631871:FOL01 RS09870
gene id: 1631871:FOL01_RS09870
uniprot id: A0A1L6RDU8
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS01050
gene id: 1631871:FOL01_RS01050
uniprot id: A0A1L6R942
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1631871:FOL01 RS11440
gene id: 1631871:FOL01_RS11440
uniprot id: A0A1L6RA97
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS01765
gene id: 1631871:FOL01_RS01765
uniprot id: A0A1L6R9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS01530
gene id: 1631871:FOL01_RS01530
uniprot id: A0A1L6R9B0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1631871:FOL01 RS06455
gene id: 1631871:FOL01_RS06455
uniprot id: A0A1L6RC31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1631871:FOL01 RS10400
gene id: 1631871:FOL01_RS10400
uniprot id: A0A1L6RED2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1631871:FOL01 RS09315
gene id: 1631871:FOL01_RS09315
uniprot id: A0A1L6RDJ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1631871:FOL01 RS06190
gene id: 1631871:FOL01_RS06190
uniprot id: A0A1L6RBX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1631871:FOL01 RS02085
gene id: 1631871:FOL01_RS02085
uniprot id: A0A1L6R9M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1631871:FOL01 RS01425
gene id: 1631871:FOL01_RS01425
uniprot id: A0A1L6R990
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS01510
gene id: 1631871:FOL01_RS01510
uniprot id: A0A1L6R9E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1631871:FOL01 RS09035
gene id: 1631871:FOL01_RS09035
uniprot id: A0A1L6RDG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1631871:FOL01 RS10235
gene id: 1631871:FOL01_RS10235
uniprot id: A0A1L6RE49
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1631871:FOL01 RS01460
gene id: 1631871:FOL01_RS01460
uniprot id: A0A1L6R9A3
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS09060
gene id: 1631871:FOL01_RS09060
uniprot id: A0A1L6RDL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1631871:FOL01 RS01975
gene id: 1631871:FOL01_RS01975
uniprot id: A0A1L6R9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1631871:FOL01 RS00275
gene id: 1631871:FOL01_RS00275
uniprot id: A0A1L6R8N5
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1631871:FOL01 RS08105
gene id: 1631871:FOL01_RS08105
uniprot id: A0A1L6RCW1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1631871:FOL01 RS05740
gene id: 1631871:FOL01_RS05740
uniprot id: A0A1L6RBM4
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS09665
gene id: 1631871:FOL01_RS09665
uniprot id: A0A1L6RDQ5
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1631871:FOL01 RS08825
gene id: 1631871:FOL01_RS08825
uniprot id: A0A1L6RDL1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS03335
gene id: 1631871:FOL01_RS03335
uniprot id: A0A1L6RA86
names: Similarity
messages: Belongs to the DtxR/MntR family.

1631871:FOL01 RS07350
gene id: 1631871:FOL01_RS07350
uniprot id: A0A1L6RCI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS07780
gene id: 1631871:FOL01_RS07780
uniprot id: A0A1L6RCY0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS08715
gene id: 1631871:FOL01_RS08715
uniprot id: A0A1L6RDB0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS07880
gene id: 1631871:FOL01_RS07880
uniprot id: A0A1L6RCZ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1631871:FOL01 RS08540
gene id: 1631871:FOL01_RS08540
uniprot id: A0A1L6RD39
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1631871:FOL01 RS04745
gene id: 1631871:FOL01_RS04745
uniprot id: A0A1L6RB30
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS08730
gene id: 1631871:FOL01_RS08730
uniprot id: A0A1L6RD81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS06170
gene id: 1631871:FOL01_RS06170
uniprot id: A0A1L6RBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

1631871:FOL01 RS09780
gene id: 1631871:FOL01_RS09780
uniprot id: A0A1L6RDS7
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS04880
gene id: 1631871:FOL01_RS04880
uniprot id: A0A1L6RB40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1631871:FOL01 RS09325
gene id: 1631871:FOL01_RS09325
uniprot id: A0A1L6RDN9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1631871:FOL01 RS07260
gene id: 1631871:FOL01_RS07260
uniprot id: A0A1L6RCJ9
names: Function
messages: Required for transformation and DNA binding.

1631871:FOL01 RS10210
gene id: 1631871:FOL01_RS10210
uniprot id: A0A1L6RE95
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS01340
gene id: 1631871:FOL01_RS01340
uniprot id: A0A1L6R9B7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1631871:FOL01 RS08830
gene id: 1631871:FOL01_RS08830
uniprot id: A0A1L6RDC2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS07385
gene id: 1631871:FOL01_RS07385
uniprot id: A0A1L6RCR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1631871:FOL01 RS08990
gene id: 1631871:FOL01_RS08990
uniprot id: A0A1L6RDD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1631871:FOL01 RS05330
gene id: 1631871:FOL01_RS05330
uniprot id: A0A1L6RBH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1631871:FOL01 RS09650
gene id: 1631871:FOL01_RS09650
uniprot id: A0A1L6RDS4
names: Similarity
messages: Belongs to the ParB family.

1631871:FOL01 RS01180
gene id: 1631871:FOL01_RS01180
uniprot id: A0A1L6R999
names: Similarity
messages: Belongs to the peptidase C56 family.

1631871:FOL01 RS07710
gene id: 1631871:FOL01_RS07710
uniprot id: A0A1L6RCN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS09050
gene id: 1631871:FOL01_RS09050
uniprot id: A0A1L6RDI7
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

1631871:FOL01 RS07425
gene id: 1631871:FOL01_RS07425
uniprot id: A0A1L6RCR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS05300
gene id: 1631871:FOL01_RS05300
uniprot id: A0A1L6RBL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1631871:FOL01 RS07970
gene id: 1631871:FOL01_RS07970
uniprot id: A0A1L6RCX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1631871:FOL01 RS04290
gene id: 1631871:FOL01_RS04290
uniprot id: A0A1L6RAU0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1631871:FOL01 RS00575
gene id: 1631871:FOL01_RS00575
uniprot id: A0A1L6R8Y7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1631871:FOL01 RS08335
gene id: 1631871:FOL01_RS08335
uniprot id: A0A1L6RD11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1631871:FOL01 RS01705
gene id: 1631871:FOL01_RS01705
uniprot id: A0A1L6R9F4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1631871:FOL01 RS01680
gene id: 1631871:FOL01_RS01680
uniprot id: A0A1L6R9E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS02640
gene id: 1631871:FOL01_RS02640
uniprot id: A0A1L6RA29
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1631871:FOL01 RS05625
gene id: 1631871:FOL01_RS05625
uniprot id: A0A1L6RBK9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1631871:FOL01 RS09010
gene id: 1631871:FOL01_RS09010
uniprot id: A0A1L6RDK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1631871:FOL01 RS02860
gene id: 1631871:FOL01_RS02860
uniprot id: A0A1L6RA74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1631871:FOL01 RS04145
gene id: 1631871:FOL01_RS04145
uniprot id: A0A1L6RAY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1631871:FOL01 RS09400
gene id: 1631871:FOL01_RS09400
uniprot id: A0A1L6RDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1631871:FOL01 RS01515
gene id: 1631871:FOL01_RS01515
uniprot id: A0A1L6R9B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1631871:FOL01 RS01155
gene id: 1631871:FOL01_RS01155
uniprot id: A0A1L6R946
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1631871:FOL01 RS03190
gene id: 1631871:FOL01_RS03190
uniprot id: A0A1L6RAC7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1631871:FOL01 RS08260
gene id: 1631871:FOL01_RS08260
uniprot id: A0A1L6RCZ2
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS06605
gene id: 1631871:FOL01_RS06605
uniprot id: A0A1L6RC71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1631871:FOL01 RS08835
gene id: 1631871:FOL01_RS08835
uniprot id: A0A1L6RD95
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS03715
gene id: 1631871:FOL01_RS03715
uniprot id: A0A1L6RAJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1631871:FOL01 RS03040
gene id: 1631871:FOL01_RS03040
uniprot id: A0A1L6RAB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1631871:FOL01 RS04610
gene id: 1631871:FOL01_RS04610
uniprot id: A0A1L6RB19
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1631871:FOL01 RS05200
gene id: 1631871:FOL01_RS05200
uniprot id: A0A1L6RBJ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1631871:FOL01 RS08645
gene id: 1631871:FOL01_RS08645
uniprot id: A0A1L6RDD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1631871:FOL01 RS02785
gene id: 1631871:FOL01_RS02785
uniprot id: A0A1L6R9Y9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

1631871:FOL01 RS02580
gene id: 1631871:FOL01_RS02580
uniprot id: A0A1L6R9Y8
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1631871:FOL01 RS07480
gene id: 1631871:FOL01_RS07480
uniprot id: A0A1L6RCM2
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS08610
gene id: 1631871:FOL01_RS08610
uniprot id: A0A1L6RD97
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1631871:FOL01 RS03380
gene id: 1631871:FOL01_RS03380
uniprot id: A0A1L6RAB8
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1631871:FOL01 RS05580
gene id: 1631871:FOL01_RS05580
uniprot id: A0A1L6RBR2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS08995
gene id: 1631871:FOL01_RS08995
uniprot id: A0A1L6RDG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1631871:FOL01 RS01920
gene id: 1631871:FOL01_RS01920
uniprot id: A0A1L6R9M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1631871:FOL01 RS03975
gene id: 1631871:FOL01_RS03975
uniprot id: A0A1L6RAL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1631871:FOL01 RS08975
gene id: 1631871:FOL01_RS08975
uniprot id: A0A1L6RDF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1631871:FOL01 RS06230
gene id: 1631871:FOL01_RS06230
uniprot id: A0A1L6RBX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1631871:FOL01 RS05360
gene id: 1631871:FOL01_RS05360
uniprot id: A0A1L6RBF3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1631871:FOL01 RS10105
gene id: 1631871:FOL01_RS10105
uniprot id: A0A1L6RE39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1631871:FOL01 RS01400
gene id: 1631871:FOL01_RS01400
uniprot id: A0A1L6R9C2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS07190
gene id: 1631871:FOL01_RS07190
uniprot id: A0A1L6RCH9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1631871:FOL01 RS05305
gene id: 1631871:FOL01_RS05305
uniprot id: A0A1L6RBE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1631871:FOL01 RS06195
gene id: 1631871:FOL01_RS06195
uniprot id: A0A1L6RC50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1631871:FOL01 RS10045
gene id: 1631871:FOL01_RS10045
uniprot id: A0A1L6RE09
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1631871:FOL01 RS07940
gene id: 1631871:FOL01_RS07940
uniprot id: A0A1L6RD14
names: Similarity
messages: Belongs to the UPF0374 family.

1631871:FOL01 RS09005
gene id: 1631871:FOL01_RS09005
uniprot id: A0A1L6RDD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1631871:FOL01 RS03215
gene id: 1631871:FOL01_RS03215
uniprot id: A0A1L6RAA9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1631871:FOL01 RS03675
gene id: 1631871:FOL01_RS03675
uniprot id: A0A1L6RAJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1631871:FOL01 RS01360
gene id: 1631871:FOL01_RS01360
uniprot id: A0A1L6R986
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1631871:FOL01 RS03305
gene id: 1631871:FOL01_RS03305
uniprot id: A0A1L6RA87
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS08870
gene id: 1631871:FOL01_RS08870
uniprot id: A0A1L6RDD5
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1631871:FOL01 RS04785
gene id: 1631871:FOL01_RS04785
uniprot id: A0A1L6RB37
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1631871:FOL01 RS08530
gene id: 1631871:FOL01_RS08530
uniprot id: A0A1L6RD77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1631871:FOL01 RS09720
gene id: 1631871:FOL01_RS09720
uniprot id: A0A1L6RDU1
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS08875
gene id: 1631871:FOL01_RS08875
uniprot id: A0A1L6RDM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1631871:FOL01 RS07390
gene id: 1631871:FOL01_RS07390
uniprot id: A0A1L6RCL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1631871:FOL01 RS08330
gene id: 1631871:FOL01_RS08330
uniprot id: A0A1L6RD90
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1631871:FOL01 RS07935
gene id: 1631871:FOL01_RS07935
uniprot id: A0A1L6RCT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1631871:FOL01 RS06035
gene id: 1631871:FOL01_RS06035
uniprot id: A0A1L6RBT3
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS08960
gene id: 1631871:FOL01_RS08960
uniprot id: A0A1L6RDJ4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1631871:FOL01 RS03220
gene id: 1631871:FOL01_RS03220
uniprot id: A0A1L6RA94
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1631871:FOL01 RS08395
gene id: 1631871:FOL01_RS08395
uniprot id: A0A1L6RD21
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1631871:FOL01 RS06150
gene id: 1631871:FOL01_RS06150
uniprot id: A0A1L6RC40
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1631871:FOL01 RS01695
gene id: 1631871:FOL01_RS01695
uniprot id: A0A1L6R9D9
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1631871:FOL01 RS06615
gene id: 1631871:FOL01_RS06615
uniprot id: A0A1L6RCA4
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1631871:FOL01 RS07855
gene id: 1631871:FOL01_RS07855
uniprot id: A0A1L6RCU1
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS07465
gene id: 1631871:FOL01_RS07465
uniprot id: A0A1L6RCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1631871:FOL01 RS06480
gene id: 1631871:FOL01_RS06480
uniprot id: A0A1L6RC52
names: Similarity
messages: Belongs to the UPF0473 family.

1631871:FOL01 RS09025
gene id: 1631871:FOL01_RS09025
uniprot id: A0A1L6RDG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1631871:FOL01 RS06790
gene id: 1631871:FOL01_RS06790
uniprot id: A0A1L6RCF2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1631871:FOL01 RS07370
gene id: 1631871:FOL01_RS07370
uniprot id: A0A1L6RCQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1631871:FOL01 RS00210
gene id: 1631871:FOL01_RS00210
uniprot id: A0A1L6R8M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS05160
gene id: 1631871:FOL01_RS05160
uniprot id: A0A1L6RBI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1631871:FOL01 RS07790
gene id: 1631871:FOL01_RS07790
uniprot id: A0A1L6RCY6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1631871:FOL01 RS01415
gene id: 1631871:FOL01_RS01415
uniprot id: A0A1L6R998
names: Similarity
messages: Belongs to the FemABX family.

1631871:FOL01 RS02725
gene id: 1631871:FOL01_RS02725
uniprot id: A0A1L6RA19
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1631871:FOL01 RS00325
gene id: 1631871:FOL01_RS00325
uniprot id: A0A1L6R8P5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS09310
gene id: 1631871:FOL01_RS09310
uniprot id: A0A1L6RDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1631871:FOL01 RS08655
gene id: 1631871:FOL01_RS08655
uniprot id: A0A1L6RDF2
names: Similarity
messages: Belongs to the peptidase M20A family.

1631871:FOL01 RS09045
gene id: 1631871:FOL01_RS09045
uniprot id: A0A1L6RDH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1631871:FOL01 RS08665
gene id: 1631871:FOL01_RS08665
uniprot id: A0A1L6RDI1
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS04505
gene id: 1631871:FOL01_RS04505
uniprot id: A0A1L6RAZ6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1631871:FOL01 RS03145
gene id: 1631871:FOL01_RS03145
uniprot id: A0A1L6RA58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

1631871:FOL01 RS07915
gene id: 1631871:FOL01_RS07915
uniprot id: A0A1L6RCV5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1631871:FOL01 RS01000
gene id: 1631871:FOL01_RS01000
uniprot id: A0A1L6R933
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1631871:FOL01 RS09255
gene id: 1631871:FOL01_RS09255
uniprot id: A0A1L6RDT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1631871:FOL01 RS07085
gene id: 1631871:FOL01_RS07085
uniprot id: A0A1L6RCK8
names: Similarity
messages: Belongs to the DCK/DGK family.

1631871:FOL01 RS02810
gene id: 1631871:FOL01_RS02810
uniprot id: A0A1L6RA63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1631871:FOL01 RS04995
gene id: 1631871:FOL01_RS04995
uniprot id: A0A1L6RBF8
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Homotetramer.

1631871:FOL01 RS01490
gene id: 1631871:FOL01_RS01490
uniprot id: A0A1L6R9B6
names: Similarity
messages: Belongs to the FGGY kinase family.

1631871:FOL01 RS01185
gene id: 1631871:FOL01_RS01185
uniprot id: A0A1L6R983
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1631871:FOL01 RS06810
gene id: 1631871:FOL01_RS06810
uniprot id: A0A1L6RC83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

1631871:FOL01 RS09860
gene id: 1631871:FOL01_RS09860
uniprot id: A0A1L6RDX3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1631871:FOL01 RS08970
gene id: 1631871:FOL01_RS08970
uniprot id: A0A1L6RDL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1631871:FOL01 RS01800
gene id: 1631871:FOL01_RS01800
uniprot id: A0A1L6R9F9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1631871:FOL01 RS00490
gene id: 1631871:FOL01_RS00490
uniprot id: A0A1L6R8Y3
names: Subcellular Location Annotation
messages: Membrane

1631871:FOL01 RS04985
gene id: 1631871:FOL01_RS04985
uniprot id: A0A1L6RBE3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS04210
gene id: 1631871:FOL01_RS04210
uniprot id: A0A1L6RAT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1631871:FOL01 RS03260
gene id: 1631871:FOL01_RS03260
uniprot id: A0A1L6RAE3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1631871:FOL01 RS06640
gene id: 1631871:FOL01_RS06640
uniprot id: A0A1L6RC77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1631871:FOL01 RS02625
gene id: 1631871:FOL01_RS02625
uniprot id: A0A1L6R9Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS02770
gene id: 1631871:FOL01_RS02770
uniprot id: A0A1L6RA14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

1631871:FOL01 RS11365
gene id: 1631871:FOL01_RS11365
uniprot id: A0A1L6RCB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1631871:FOL01 RS08710
gene id: 1631871:FOL01_RS08710
uniprot id: A0A1L6RDG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1631871:FOL01 RS00060
gene id: 1631871:FOL01_RS00060
uniprot id: A0A1L6R8K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1631871:FOL01 RS06040
gene id: 1631871:FOL01_RS06040
uniprot id: A0A1L6RC10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1631871:FOL01 RS00365
gene id: 1631871:FOL01_RS00365
uniprot id: A0A1L6R8Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1631871:FOL01 RS08155
gene id: 1631871:FOL01_RS08155
uniprot id: A0A1L6RCX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1631871:FOL01 RS06285
gene id: 1631871:FOL01_RS06285
uniprot id: A0A1L6RC63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1631871:FOL01 RS09990
gene id: 1631871:FOL01_RS09990
uniprot id: A0A1L6RDZ8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1631871:FOL01 RS01575
gene id: 1631871:FOL01_RS01575
uniprot id: A0A1L6R9G3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS03755
gene id: 1631871:FOL01_RS03755
uniprot id: A0A1L6RAP4
names: Subcellular Location Annotation
messages: Cytoplasm

1631871:FOL01 RS09640
gene id: 1631871:FOL01_RS09640
uniprot id: A0A1L6RDQ0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1631871:FOL01 RS02840
gene id: 1631871:FOL01_RS02840
uniprot id: A0A1L6RA67
names: Similarity
messages: Belongs to the peptidase C59 family.

1631871:FOL01 RS08325
gene id: 1631871:FOL01_RS08325
uniprot id: A0A1L6RCZ5
names: Similarity
messages: Belongs to the FemABX family.

1631871:FOL01 RS04595
gene id: 1631871:FOL01_RS04595
uniprot id: A0A1L6RAZ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

1631871:FOL01 RS10110
gene id: 1631871:FOL01_RS10110
uniprot id: A0A1L6RDZ7
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1631871:FOL01 RS03815
gene id: 1631871:FOL01_RS03815
uniprot id: A0A1L6RAK6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1631871:FOL01 RS01725
gene id: 1631871:FOL01_RS01725
uniprot id: A0A1L6R9G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1631871:FOL01 RS03645
gene id: 1631871:FOL01_RS03645
uniprot id: A0A1L6RAP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1631871:FOL01 RS09740
gene id: 1631871:FOL01_RS09740
uniprot id: A0A1L6RDS1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1631871:FOL01 RS01580
gene id: 1631871:FOL01_RS01580
uniprot id: A0A1L6R9C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1631871:FOL01 RS06155
gene id: 1631871:FOL01_RS06155
uniprot id: A0A1L6RBZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1631871:FOL01 RS07925
gene id: 1631871:FOL01_RS07925
uniprot id: A0A1L6RCS6
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1631871:FOL01 RS09700
gene id: 1631871:FOL01_RS09700
uniprot id: A0A1L6RDT8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.