1622118:Lupro RS04710
gene id: 1622118:Lupro_RS04710
uniprot id: A0A0X8G5U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1622118:Lupro RS03350
gene id: 1622118:Lupro_RS03350
uniprot id: A0A120IE22
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1622118:Lupro RS03275
gene id: 1622118:Lupro_RS03275
uniprot id: A0A120IE23
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1622118:Lupro RS11485
gene id: 1622118:Lupro_RS11485
uniprot id: A0A0X8G8Y9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1622118:Lupro RS04520
gene id: 1622118:Lupro_RS04520
uniprot id: A0A0X8G5R3
names: Similarity
messages: Belongs to the LOG family.

1622118:Lupro RS05335
gene id: 1622118:Lupro_RS05335
uniprot id: A0A0X8G5Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1622118:Lupro RS10840
gene id: 1622118:Lupro_RS10840
uniprot id: A0A0X8G7Y0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1622118:Lupro RS00550
gene id: 1622118:Lupro_RS00550
uniprot id: A0A0X8G4B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1622118:Lupro RS11870
gene id: 1622118:Lupro_RS11870
uniprot id: A0A0X8G8D0
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1622118:Lupro RS03725
gene id: 1622118:Lupro_RS03725
uniprot id: A0A0X8G5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1622118:Lupro RS06630
gene id: 1622118:Lupro_RS06630
uniprot id: A0A0X8G6D7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1622118:Lupro RS05460
gene id: 1622118:Lupro_RS05460
uniprot id: A0A109RNA8
names: Similarity
messages: Belongs to the TPP enzyme family.

1622118:Lupro RS07130
gene id: 1622118:Lupro_RS07130
uniprot id: A0A0X8G6P7
names: Similarity
messages: Belongs to the HypE family.

1622118:Lupro RS00825
gene id: 1622118:Lupro_RS00825
uniprot id: A0A0X8G4H5
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS06560
gene id: 1622118:Lupro_RS06560
uniprot id: A0A0X8G6E2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1622118:Lupro RS03825
gene id: 1622118:Lupro_RS03825
uniprot id: A0A0X8G5J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1622118:Lupro RS01260
gene id: 1622118:Lupro_RS01260
uniprot id: A0A109RMX8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1622118:Lupro RS00715
gene id: 1622118:Lupro_RS00715
uniprot id: A0A0X8G4E4
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1622118:Lupro RS09955
gene id: 1622118:Lupro_RS09955
uniprot id: A0A0X8G7Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1622118:Lupro RS12500
gene id: 1622118:Lupro_RS12500
uniprot id: A0A109RQ55
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1622118:Lupro RS10295
gene id: 1622118:Lupro_RS10295
uniprot id: A0A0X8G7R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1622118:Lupro RS06875
gene id: 1622118:Lupro_RS06875
uniprot id: A0A0X8G6G8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1622118:Lupro RS10065
gene id: 1622118:Lupro_RS10065
uniprot id: A0A0X8G7Q6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1622118:Lupro RS02455
gene id: 1622118:Lupro_RS02455
uniprot id: A0A0X8G5T3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1622118:Lupro RS00875
gene id: 1622118:Lupro_RS00875
uniprot id: A0A109RMX4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1622118:Lupro RS13005
gene id: 1622118:Lupro_RS13005
uniprot id: A0A0X8G8N1
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS02145
gene id: 1622118:Lupro_RS02145
uniprot id: A0A109RN23
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1622118:Lupro RS06645
gene id: 1622118:Lupro_RS06645
uniprot id: A0A0X8G6I3
names: Similarity
messages: Belongs to the Skp family.

1622118:Lupro RS11765
gene id: 1622118:Lupro_RS11765
uniprot id: A0A0X8G881
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1622118:Lupro RS03815
gene id: 1622118:Lupro_RS03815
uniprot id: A0A0X8G5J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1622118:Lupro RS00170
gene id: 1622118:Lupro_RS00170
uniprot id: A0A109RMM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1622118:Lupro RS11175
gene id: 1622118:Lupro_RS11175
uniprot id: A0A0X8G825
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1622118:Lupro RS02205
gene id: 1622118:Lupro_RS02205
uniprot id: A0A0X8G4Z1
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1622118:Lupro RS06955
gene id: 1622118:Lupro_RS06955
uniprot id: A0A0X8G6H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1622118:Lupro RS01670
gene id: 1622118:Lupro_RS01670
uniprot id: A0A0X8G4S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1622118:Lupro RS04475
gene id: 1622118:Lupro_RS04475
uniprot id: A0A0X8G5P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1622118:Lupro RS02130
gene id: 1622118:Lupro_RS02130
uniprot id: A0A0X8G5N7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1622118:Lupro RS12270
gene id: 1622118:Lupro_RS12270
uniprot id: A0A0X8G8E6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1622118:Lupro RS05925
gene id: 1622118:Lupro_RS05925
uniprot id: A0A0X8G655
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1622118:Lupro RS09935
gene id: 1622118:Lupro_RS09935
uniprot id: A0A109RNZ1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1622118:Lupro RS03830
gene id: 1622118:Lupro_RS03830
uniprot id: A0A0X8G5K0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1622118:Lupro RS11875
gene id: 1622118:Lupro_RS11875
uniprot id: A0A0X8G8F2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1622118:Lupro RS03560
gene id: 1622118:Lupro_RS03560
uniprot id: A0A0X8G5G2
names: Similarity
messages: Belongs to the NusB family.

1622118:Lupro RS11215
gene id: 1622118:Lupro_RS11215
uniprot id: A0A109RP08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1622118:Lupro RS05945
gene id: 1622118:Lupro_RS05945
uniprot id: A0A0X8G691
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1622118:Lupro RS09995
gene id: 1622118:Lupro_RS09995
uniprot id: A0A0X8G7R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1622118:Lupro RS02860
gene id: 1622118:Lupro_RS02860
uniprot id: A0A109RN72
names: Similarity
messages: Belongs to the 3-hydroxybenzoate 6-hydroxylase family.

1622118:Lupro RS02190
gene id: 1622118:Lupro_RS02190
uniprot id: A0A0X8G4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1622118:Lupro RS13015
gene id: 1622118:Lupro_RS13015
uniprot id: A0A0X8G8N9
names: Similarity
messages: Belongs to the DinB family.

1622118:Lupro RS03665
gene id: 1622118:Lupro_RS03665
uniprot id: A0A0X8G5H8
names: Similarity
messages: Belongs to the Dps family.

1622118:Lupro RS11920
gene id: 1622118:Lupro_RS11920
uniprot id: A0A0X8G8A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1622118:Lupro RS08735
gene id: 1622118:Lupro_RS08735
uniprot id: A0A109RNQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS02175
gene id: 1622118:Lupro_RS02175
uniprot id: A0A0X8G4Y5
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS07885
gene id: 1622118:Lupro_RS07885
uniprot id: A0A0X8G6U8
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS12355
gene id: 1622118:Lupro_RS12355
uniprot id: A0A0X8G8L1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1622118:Lupro RS11515
gene id: 1622118:Lupro_RS11515
uniprot id: A0A0X8G8B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1622118:Lupro RS07335
gene id: 1622118:Lupro_RS07335
uniprot id: A0A109RNP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1622118:Lupro RS11335
gene id: 1622118:Lupro_RS11335
uniprot id: A0A0X8G836
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1622118:Lupro RS04960
gene id: 1622118:Lupro_RS04960
uniprot id: A0A0X8G5X2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1622118:Lupro RS01680
gene id: 1622118:Lupro_RS01680
uniprot id: A0A0X8G4R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1622118:Lupro RS10515
gene id: 1622118:Lupro_RS10515
uniprot id: A0A109RQ70
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1622118:Lupro RS10820
gene id: 1622118:Lupro_RS10820
uniprot id: A0A120IEH7
names: Similarity
messages: Belongs to the fabD family.

1622118:Lupro RS08760
gene id: 1622118:Lupro_RS08760
uniprot id: A0A109RNQ4
names: Similarity
messages: Belongs to the peptidase S41A family.

1622118:Lupro RS02475
gene id: 1622118:Lupro_RS02475
uniprot id: A0A109RP96
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS04775
gene id: 1622118:Lupro_RS04775
uniprot id: A0A0X8G5U3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1622118:Lupro RS06045
gene id: 1622118:Lupro_RS06045
uniprot id: A0A120IE77
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1622118:Lupro RS06650
gene id: 1622118:Lupro_RS06650
uniprot id: A0A0X8G6I4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1622118:Lupro RS06510
gene id: 1622118:Lupro_RS06510
uniprot id: A0A0X8G779
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS05915
gene id: 1622118:Lupro_RS05915
uniprot id: A0A0X8G692
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1622118:Lupro RS07255
gene id: 1622118:Lupro_RS07255
uniprot id: A0A120IEA4
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS09345
gene id: 1622118:Lupro_RS09345
uniprot id: A0A109RNV2
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS05140
gene id: 1622118:Lupro_RS05140
uniprot id: A0A109RNE4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS06445
gene id: 1622118:Lupro_RS06445
uniprot id: A0A0X8G8U5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1622118:Lupro RS05240
gene id: 1622118:Lupro_RS05240
uniprot id: A0A0X8G601
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS01820
gene id: 1622118:Lupro_RS01820
uniprot id: A0A0X8G4U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1622118:Lupro RS04145
gene id: 1622118:Lupro_RS04145
uniprot id: A0A0X8G5P0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1622118:Lupro RS04105
gene id: 1622118:Lupro_RS04105
uniprot id: A0A109RNA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS01955
gene id: 1622118:Lupro_RS01955
uniprot id: A0A0X8G4W1
names: Similarity
messages: Belongs to the peptidase M1 family.

1622118:Lupro RS09880
gene id: 1622118:Lupro_RS09880
uniprot id: A0A0X8G7K6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1622118:Lupro RS09350
gene id: 1622118:Lupro_RS09350
uniprot id: A0A120IEN4
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS05585
gene id: 1622118:Lupro_RS05585
uniprot id: A0A0X8G642
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS00575
gene id: 1622118:Lupro_RS00575
uniprot id: A0A109RMU1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1622118:Lupro RS00250
gene id: 1622118:Lupro_RS00250
uniprot id: A0A0X8G8V1
names: Similarity
messages: Belongs to the peptidase C40 family.

1622118:Lupro RS02525
gene id: 1622118:Lupro_RS02525
uniprot id: A0A109RN27
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS04415
gene id: 1622118:Lupro_RS04415
uniprot id: A0A0X8G5P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1622118:Lupro RS12875
gene id: 1622118:Lupro_RS12875
uniprot id: A0A0X8G8Q0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1622118:Lupro RS11460
gene id: 1622118:Lupro_RS11460
uniprot id: A0A0X8G868
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1622118:Lupro RS11600
gene id: 1622118:Lupro_RS11600
uniprot id: A0A0X8G8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS12380
gene id: 1622118:Lupro_RS12380
uniprot id: A0A0X8G8H5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

1622118:Lupro RS12625
gene id: 1622118:Lupro_RS12625
uniprot id: A0A0X8G8L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1622118:Lupro RS09430
gene id: 1622118:Lupro_RS09430
uniprot id: A0A109RPE3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1622118:Lupro RS11280
gene id: 1622118:Lupro_RS11280
uniprot id: A0A0X8G849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1622118:Lupro RS01565
gene id: 1622118:Lupro_RS01565
uniprot id: A0A0X8G4P9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

1622118:Lupro RS10040
gene id: 1622118:Lupro_RS10040
uniprot id: A0A0X8G7S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1622118:Lupro RS04555
gene id: 1622118:Lupro_RS04555
uniprot id: A0A109RNA2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1622118:Lupro RS05005
gene id: 1622118:Lupro_RS05005
uniprot id: A0A0X8G5X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1622118:Lupro RS10920
gene id: 1622118:Lupro_RS10920
uniprot id: A0A0X8G7Y9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS01845
gene id: 1622118:Lupro_RS01845
uniprot id: A0A109RPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1622118:Lupro RS08755
gene id: 1622118:Lupro_RS08755
uniprot id: A0A109RNU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1622118:Lupro RS12090
gene id: 1622118:Lupro_RS12090
uniprot id: A0A0X8G8G3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS03405
gene id: 1622118:Lupro_RS03405
uniprot id: A0A0X8G5B8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1622118:Lupro RS02635
gene id: 1622118:Lupro_RS02635
uniprot id: A0A109RMZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

1622118:Lupro RS05950
gene id: 1622118:Lupro_RS05950
uniprot id: A0A0X8G670
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1622118:Lupro RS05765
gene id: 1622118:Lupro_RS05765
uniprot id: A0A0X8G637
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1622118:Lupro RS10360
gene id: 1622118:Lupro_RS10360
uniprot id: A0A0X8G7W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS06480
gene id: 1622118:Lupro_RS06480
uniprot id: A0A0X8G6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1622118:Lupro RS07650
gene id: 1622118:Lupro_RS07650
uniprot id: A0A109RPI6
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1622118:Lupro RS12080
gene id: 1622118:Lupro_RS12080
uniprot id: A0A0X8G8C3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1622118:Lupro RS08030
gene id: 1622118:Lupro_RS08030
uniprot id: A0A0X8G907
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS09585
gene id: 1622118:Lupro_RS09585
uniprot id: A0A109RNW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1622118:Lupro RS09305
gene id: 1622118:Lupro_RS09305
uniprot id: A0A0X8G7H4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1622118:Lupro RS13785
gene id: 1622118:Lupro_RS13785
uniprot id: A0A0X8G669
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS11285
gene id: 1622118:Lupro_RS11285
uniprot id: A0A0X8G859
names: Similarity
messages: Belongs to the MreC family.

1622118:Lupro RS13820
gene id: 1622118:Lupro_RS13820
uniprot id: A0A0X8G542
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1622118:Lupro RS10695
gene id: 1622118:Lupro_RS10695
uniprot id: A0A0X8G7X0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1622118:Lupro RS07675
gene id: 1622118:Lupro_RS07675
uniprot id: A0A0X8G6R7
names: Similarity
messages: Belongs to the ribF family.

1622118:Lupro RS01120
gene id: 1622118:Lupro_RS01120
uniprot id: A0A109RMY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1622118:Lupro RS11525
gene id: 1622118:Lupro_RS11525
uniprot id: A0A0X8G846
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1622118:Lupro RS06200
gene id: 1622118:Lupro_RS06200
uniprot id: A0A0X8G742
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS08200
gene id: 1622118:Lupro_RS08200
uniprot id: A0A120IEC5
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1622118:Lupro RS05980
gene id: 1622118:Lupro_RS05980
uniprot id: A0A109RPL9
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS02390
gene id: 1622118:Lupro_RS02390
uniprot id: A0A109RN56
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1622118:Lupro RS04360
gene id: 1622118:Lupro_RS04360
uniprot id: A0A0X8G5Q7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS00525
gene id: 1622118:Lupro_RS00525
uniprot id: A0A120IDW7
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS06910
gene id: 1622118:Lupro_RS06910
uniprot id: A0A0X8G7B5
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1622118:Lupro RS05790
gene id: 1622118:Lupro_RS05790
uniprot id: A0A0X8G652
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1622118:Lupro RS03480
gene id: 1622118:Lupro_RS03480
uniprot id: A0A0X8G5F5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1622118:Lupro RS01895
gene id: 1622118:Lupro_RS01895
uniprot id: A0A109RQF9
names: Similarity
messages: Belongs to the threonine synthase family.

1622118:Lupro RS12825
gene id: 1622118:Lupro_RS12825
uniprot id: A0A120IEL7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1622118:Lupro RS05050
gene id: 1622118:Lupro_RS05050
uniprot id: A0A0X8G6Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1622118:Lupro RS00395
gene id: 1622118:Lupro_RS00395
uniprot id: A0A0X8G4C4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1622118:Lupro RS10570
gene id: 1622118:Lupro_RS10570
uniprot id: A0A0X8G8M9
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1622118:Lupro RS01515
gene id: 1622118:Lupro_RS01515
uniprot id: A0A0X8G8U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1622118:Lupro RS04435
gene id: 1622118:Lupro_RS04435
uniprot id: A0A0X8G5R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1622118:Lupro RS04890
gene id: 1622118:Lupro_RS04890
uniprot id: A0A0X8G5T9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1622118:Lupro RS07155
gene id: 1622118:Lupro_RS07155
uniprot id: A0A0X8G7D9
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1622118:Lupro RS02565
gene id: 1622118:Lupro_RS02565
uniprot id: A0A0X8G537
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1622118:Lupro RS04320
gene id: 1622118:Lupro_RS04320
uniprot id: A0A120IE43
names: Similarity
messages: Belongs to the acylphosphatase family.

1622118:Lupro RS09580
gene id: 1622118:Lupro_RS09580
uniprot id: A0A0X8G7L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS06105
gene id: 1622118:Lupro_RS06105
uniprot id: A0A0X8G6B1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1622118:Lupro RS05105
gene id: 1622118:Lupro_RS05105
uniprot id: A0A0X8G5Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1622118:Lupro RS02355
gene id: 1622118:Lupro_RS02355
uniprot id: A0A0X8G513
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1622118:Lupro RS06735
gene id: 1622118:Lupro_RS06735
uniprot id: A0A0X8G6H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1622118:Lupro RS03670
gene id: 1622118:Lupro_RS03670
uniprot id: A0A0X8G5F9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1622118:Lupro RS04995
gene id: 1622118:Lupro_RS04995
uniprot id: A0A109RPH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1622118:Lupro RS09060
gene id: 1622118:Lupro_RS09060
uniprot id: A0A109RPQ5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1622118:Lupro RS05415
gene id: 1622118:Lupro_RS05415
uniprot id: A0A0X8G5Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1622118:Lupro RS12395
gene id: 1622118:Lupro_RS12395
uniprot id: A0A109RP61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1622118:Lupro RS04080
gene id: 1622118:Lupro_RS04080
uniprot id: A0A0X8G5K6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1622118:Lupro RS10800
gene id: 1622118:Lupro_RS10800
uniprot id: A0A109RP15
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1622118:Lupro RS07345
gene id: 1622118:Lupro_RS07345
uniprot id: A0A109RNI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1622118:Lupro RS11265
gene id: 1622118:Lupro_RS11265
uniprot id: A0A0X8G8X2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1622118:Lupro RS01790
gene id: 1622118:Lupro_RS01790
uniprot id: A0A120IDZ3
names: Similarity
messages: Belongs to the HSP15 family.

1622118:Lupro RS09960
gene id: 1622118:Lupro_RS09960
uniprot id: A0A0X8G7M0
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS05315
gene id: 1622118:Lupro_RS05315
uniprot id: A0A0X8G5X8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS05535
gene id: 1622118:Lupro_RS05535
uniprot id: A0A0X8G620
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1622118:Lupro RS12670
gene id: 1622118:Lupro_RS12670
uniprot id: A0A0X8G8Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1622118:Lupro RS04945
gene id: 1622118:Lupro_RS04945
uniprot id: A0A0X8G5U4
names: Similarity
messages: Belongs to the arginase family.

1622118:Lupro RS12880
gene id: 1622118:Lupro_RS12880
uniprot id: A0A0X8G8N6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1622118:Lupro RS05120
gene id: 1622118:Lupro_RS05120
uniprot id: A0A109RNB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1622118:Lupro RS06075
gene id: 1622118:Lupro_RS06075
uniprot id: A0A0X8G6B0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1622118:Lupro RS10590
gene id: 1622118:Lupro_RS10590
uniprot id: A0A120IEH3
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

1622118:Lupro RS04335
gene id: 1622118:Lupro_RS04335
uniprot id: A0A0X8G5N2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1622118:Lupro RS01190
gene id: 1622118:Lupro_RS01190
uniprot id: A0A109RMR8
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS05010
gene id: 1622118:Lupro_RS05010
uniprot id: A0A0X8G5X7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1622118:Lupro RS04060
gene id: 1622118:Lupro_RS04060
uniprot id: A0A0X8G5J9
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1622118:Lupro RS06575
gene id: 1622118:Lupro_RS06575
uniprot id: A0A0X8G6H1
names: Similarity
messages: Belongs to the peptidase M1 family.

1622118:Lupro RS01905
gene id: 1622118:Lupro_RS01905
uniprot id: A0A109RMW5
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1622118:Lupro RS05040
gene id: 1622118:Lupro_RS05040
uniprot id: A0A0X8G5W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1622118:Lupro RS08700
gene id: 1622118:Lupro_RS08700
uniprot id: A0A0X8G775
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1622118:Lupro RS06345
gene id: 1622118:Lupro_RS06345
uniprot id: A0A0X8G6C7
names: Similarity
messages: Belongs to the thioredoxin family.

1622118:Lupro RS06360
gene id: 1622118:Lupro_RS06360
uniprot id: A0A120IE85
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1622118:Lupro RS07860
gene id: 1622118:Lupro_RS07860
uniprot id: A0A0X8G7M4
names: Similarity
messages: Belongs to the RecJ family.

1622118:Lupro RS11185
gene id: 1622118:Lupro_RS11185
uniprot id: A0A0X8G841
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1622118:Lupro RS12000
gene id: 1622118:Lupro_RS12000
uniprot id: A0A0X8G8B5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1622118:Lupro RS07475
gene id: 1622118:Lupro_RS07475
uniprot id: A0A0X8G6R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1622118:Lupro RS06565
gene id: 1622118:Lupro_RS06565
uniprot id: A0A0X8G6I2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS02140
gene id: 1622118:Lupro_RS02140
uniprot id: A0A109RN47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1622118:Lupro RS00190
gene id: 1622118:Lupro_RS00190
uniprot id: A0A0X8G483
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS01590
gene id: 1622118:Lupro_RS01590
uniprot id: A0A0X8G4R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1622118:Lupro RS04430
gene id: 1622118:Lupro_RS04430
uniprot id: A0A0X8G5N5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1622118:Lupro RS00460
gene id: 1622118:Lupro_RS00460
uniprot id: A0A0X8G8P9
names: Similarity
messages: Belongs to the peptidase S8 family.

1622118:Lupro RS00600
gene id: 1622118:Lupro_RS00600
uniprot id: A0A109RMW7
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS03095
gene id: 1622118:Lupro_RS03095
uniprot id: A0A109RN84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1622118:Lupro RS12280
gene id: 1622118:Lupro_RS12280
uniprot id: A0A0X8G8E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1622118:Lupro RS05595
gene id: 1622118:Lupro_RS05595
uniprot id: A0A0X8G618
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1622118:Lupro RS10275
gene id: 1622118:Lupro_RS10275
uniprot id: A0A109RQ57
names: Similarity
messages: Belongs to the asparaginase 1 family.

1622118:Lupro RS09255
gene id: 1622118:Lupro_RS09255
uniprot id: A0A0X8G7F1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS09965
gene id: 1622118:Lupro_RS09965
uniprot id: A0A0X8G7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1622118:Lupro RS00710
gene id: 1622118:Lupro_RS00710
uniprot id: A0A0X8G4D6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1622118:Lupro RS12750
gene id: 1622118:Lupro_RS12750
uniprot id: A0A109RQ64
names: Similarity
messages: Belongs to the UPF0173 family.

1622118:Lupro RS00685
gene id: 1622118:Lupro_RS00685
uniprot id: A0A109RP34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1622118:Lupro RS08140
gene id: 1622118:Lupro_RS08140
uniprot id: A0A0X8G6Y3
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS01370
gene id: 1622118:Lupro_RS01370
uniprot id: A0A109RMU3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1622118:Lupro RS05100
gene id: 1622118:Lupro_RS05100
uniprot id: A0A0X8G606
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1622118:Lupro RS08115
gene id: 1622118:Lupro_RS08115
uniprot id: A0A109RPK8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1622118:Lupro RS01550
gene id: 1622118:Lupro_RS01550
uniprot id: A0A0X8G4Q5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1622118:Lupro RS04300
gene id: 1622118:Lupro_RS04300
uniprot id: A0A0X8G8T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1622118:Lupro RS12640
gene id: 1622118:Lupro_RS12640
uniprot id: A0A0X8G996
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS10940
gene id: 1622118:Lupro_RS10940
uniprot id: A0A109RPC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1622118:Lupro RS06260
gene id: 1622118:Lupro_RS06260
uniprot id: A0A0X8G6D4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1622118:Lupro RS00530
gene id: 1622118:Lupro_RS00530
uniprot id: A0A0X8G4C1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1622118:Lupro RS10605
gene id: 1622118:Lupro_RS10605
uniprot id: A0A0X8G7V0
names: Similarity
messages: Belongs to the universal stress protein A family.

1622118:Lupro RS06085
gene id: 1622118:Lupro_RS06085
uniprot id: A0A0X8G672
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1622118:Lupro RS03855
gene id: 1622118:Lupro_RS03855
uniprot id: A0A109RNB0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS09760
gene id: 1622118:Lupro_RS09760
uniprot id: A0A109RNV7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1622118:Lupro RS01645
gene id: 1622118:Lupro_RS01645
uniprot id: A0A0X8G4S7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1622118:Lupro RS01700
gene id: 1622118:Lupro_RS01700
uniprot id: A0A109RMW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1622118:Lupro RS04975
gene id: 1622118:Lupro_RS04975
uniprot id: A0A0X8G6P1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1622118:Lupro RS06135
gene id: 1622118:Lupro_RS06135
uniprot id: A0A109RNI3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1622118:Lupro RS12695
gene id: 1622118:Lupro_RS12695
uniprot id: A0A0X8G8L8
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1622118:Lupro RS09485
gene id: 1622118:Lupro_RS09485
uniprot id: A0A0X8G7J7
names: Similarity
messages: Belongs to the universal stress protein A family.

1622118:Lupro RS06010
gene id: 1622118:Lupro_RS06010
uniprot id: A0A0X8G6B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1622118:Lupro RS07235
gene id: 1622118:Lupro_RS07235
uniprot id: A0A0X8G7E6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1622118:Lupro RS00480
gene id: 1622118:Lupro_RS00480
uniprot id: A0A0X8G8P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1622118:Lupro RS08885
gene id: 1622118:Lupro_RS08885
uniprot id: A0A109RNT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS08525
gene id: 1622118:Lupro_RS08525
uniprot id: A0A109RNT0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1622118:Lupro RS02365
gene id: 1622118:Lupro_RS02365
uniprot id: A0A0X8G510
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1622118:Lupro RS07250
gene id: 1622118:Lupro_RS07250
uniprot id: A0A120IEA2
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1622118:Lupro RS05055
gene id: 1622118:Lupro_RS05055
uniprot id: A0A120IE58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1622118:Lupro RS03320
gene id: 1622118:Lupro_RS03320
uniprot id: A0A0X8G5C9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1622118:Lupro RS08330
gene id: 1622118:Lupro_RS08330
uniprot id: A0A0X8G727
names: Similarity
messages: Belongs to the peptidase S8 family.

1622118:Lupro RS06860
gene id: 1622118:Lupro_RS06860
uniprot id: A0A0X8G6G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1622118:Lupro RS01405
gene id: 1622118:Lupro_RS01405
uniprot id: A0A0X8G4P1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS10185
gene id: 1622118:Lupro_RS10185
uniprot id: A0A109RP14
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1622118:Lupro RS04325
gene id: 1622118:Lupro_RS04325
uniprot id: A0A0X8G5L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1622118:Lupro RS04410
gene id: 1622118:Lupro_RS04410
uniprot id: A0A0X8G5M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1622118:Lupro RS02380
gene id: 1622118:Lupro_RS02380
uniprot id: A0A0X8G5S1
names: Similarity
messages: Belongs to the peptidase S9C family.

1622118:Lupro RS09320
gene id: 1622118:Lupro_RS09320
uniprot id: A0A0X8G7C8
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1622118:Lupro RS04820
gene id: 1622118:Lupro_RS04820
uniprot id: A0A0X8G6L9
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1622118:Lupro RS08130
gene id: 1622118:Lupro_RS08130
uniprot id: A0A0X8G719
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1622118:Lupro RS01530
gene id: 1622118:Lupro_RS01530
uniprot id: A0A120IDY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

1622118:Lupro RS04280
gene id: 1622118:Lupro_RS04280
uniprot id: A0A0X8G5Q5
names: Subcellular Location Annotation
messages: Cytoplasm

1622118:Lupro RS03015
gene id: 1622118:Lupro_RS03015
uniprot id: A0A120IE20
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1622118:Lupro RS07510
gene id: 1622118:Lupro_RS07510
uniprot id: A0A0X8G6P8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1622118:Lupro RS04500
gene id: 1622118:Lupro_RS04500
uniprot id: A0A109RP68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1622118:Lupro RS06140
gene id: 1622118:Lupro_RS06140
uniprot id: A0A0X8G8U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1622118:Lupro RS10020
gene id: 1622118:Lupro_RS10020
uniprot id: A0A109RNV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1622118:Lupro RS12265
gene id: 1622118:Lupro_RS12265
uniprot id: A0A0X8G8K0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS00255
gene id: 1622118:Lupro_RS00255
uniprot id: A0A0X8G508
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1622118:Lupro RS06100
gene id: 1622118:Lupro_RS06100
uniprot id: A0A0X8G6A8
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS06475
gene id: 1622118:Lupro_RS06475
uniprot id: A0A0X8G6B6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1622118:Lupro RS00120
gene id: 1622118:Lupro_RS00120
uniprot id: A0A0X8G493
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1622118:Lupro RS09195
gene id: 1622118:Lupro_RS09195
uniprot id: A0A109RNS0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1622118:Lupro RS07755
gene id: 1622118:Lupro_RS07755
uniprot id: A0A0X8G6U0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1622118:Lupro RS07780
gene id: 1622118:Lupro_RS07780
uniprot id: A0A109RNL7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS12410
gene id: 1622118:Lupro_RS12410
uniprot id: A0A0X8G8Z0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1622118:Lupro RS11340
gene id: 1622118:Lupro_RS11340
uniprot id: A0A0X8G893
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1622118:Lupro RS08345
gene id: 1622118:Lupro_RS08345
uniprot id: A0A0X8G7T6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1622118:Lupro RS08425
gene id: 1622118:Lupro_RS08425
uniprot id: A0A109RNR4
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS04075
gene id: 1622118:Lupro_RS04075
uniprot id: A0A0X8G5N1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1622118:Lupro RS07430
gene id: 1622118:Lupro_RS07430
uniprot id: A0A109RPS8
names: Similarity
messages: Belongs to the group II decarboxylase family.

1622118:Lupro RS09710
gene id: 1622118:Lupro_RS09710
uniprot id: A0A0X8G7J0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS10050
gene id: 1622118:Lupro_RS10050
uniprot id: A0A0X8G7M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

1622118:Lupro RS09615
gene id: 1622118:Lupro_RS09615
uniprot id: A0A0X8G7H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1622118:Lupro RS04255
gene id: 1622118:Lupro_RS04255
uniprot id: A0A0X8G5N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1622118:Lupro RS06535
gene id: 1622118:Lupro_RS06535
uniprot id: A0A0X8G6C5
names: Similarity
messages: Belongs to the peptidase S49 family.

1622118:Lupro RS02510
gene id: 1622118:Lupro_RS02510
uniprot id: A0A0X8G532
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1622118:Lupro RS03865
gene id: 1622118:Lupro_RS03865
uniprot id: A0A109RN44
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS11055
gene id: 1622118:Lupro_RS11055
uniprot id: A0A120IEI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1622118:Lupro RS00115
gene id: 1622118:Lupro_RS00115
uniprot id: A0A0X8G472
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1622118:Lupro RS02230
gene id: 1622118:Lupro_RS02230
uniprot id: A0A109RMW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1622118:Lupro RS00310
gene id: 1622118:Lupro_RS00310
uniprot id: A0A0X8G484
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1622118:Lupro RS07715
gene id: 1622118:Lupro_RS07715
uniprot id: A0A120IEB6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1622118:Lupro RS04485
gene id: 1622118:Lupro_RS04485
uniprot id: A0A0X8G6H6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1622118:Lupro RS04695
gene id: 1622118:Lupro_RS04695
uniprot id: A0A0X8G5R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1622118:Lupro RS12940
gene id: 1622118:Lupro_RS12940
uniprot id: A0A0X8G8M6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1622118:Lupro RS04375
gene id: 1622118:Lupro_RS04375
uniprot id: A0A0X8G5N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1622118:Lupro RS12660
gene id: 1622118:Lupro_RS12660
uniprot id: A0A109RP73
names: Similarity
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.

1622118:Lupro RS08595
gene id: 1622118:Lupro_RS08595
uniprot id: A0A109RNQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1622118:Lupro RS07970
gene id: 1622118:Lupro_RS07970
uniprot id: A0A0X8G6Z1
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS01355
gene id: 1622118:Lupro_RS01355
uniprot id: A0A120IDY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1622118:Lupro RS01475
gene id: 1622118:Lupro_RS01475
uniprot id: A0A0X8G4N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS11620
gene id: 1622118:Lupro_RS11620
uniprot id: A0A0X8G8A5
names: Subcellular Location Annotation
messages: Cytoplasm

1622118:Lupro RS09525
gene id: 1622118:Lupro_RS09525
uniprot id: A0A109RNT2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1622118:Lupro RS03960
gene id: 1622118:Lupro_RS03960
uniprot id: A0A0X8G5K9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1622118:Lupro RS03235
gene id: 1622118:Lupro_RS03235
uniprot id: A0A0X8G5C1
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS02185
gene id: 1622118:Lupro_RS02185
uniprot id: A0A0X8G4W3
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1622118:Lupro RS12855
gene id: 1622118:Lupro_RS12855
uniprot id: A0A0X8G8M0
names: Similarity
messages: Belongs to the nitroreductase family.

1622118:Lupro RS12475
gene id: 1622118:Lupro_RS12475
uniprot id: A0A0X8G8L9
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS13050
gene id: 1622118:Lupro_RS13050
uniprot id: A0A0X8G8T6
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1622118:Lupro RS00405
gene id: 1622118:Lupro_RS00405
uniprot id: A0A0X8G4D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1622118:Lupro RS07225
gene id: 1622118:Lupro_RS07225
uniprot id: A0A0X8G6N9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1622118:Lupro RS09435
gene id: 1622118:Lupro_RS09435
uniprot id: A0A0X8G875
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1622118:Lupro RS07275
gene id: 1622118:Lupro_RS07275
uniprot id: A0A0X8G6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1622118:Lupro RS12950
gene id: 1622118:Lupro_RS12950
uniprot id: A0A0X8G8R0
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS06040
gene id: 1622118:Lupro_RS06040
uniprot id: A0A0X8G722
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1622118:Lupro RS07165
gene id: 1622118:Lupro_RS07165
uniprot id: A0A109RNI7
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1622118:Lupro RS10420
gene id: 1622118:Lupro_RS10420
uniprot id: A0A109RP24
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1622118:Lupro RS03930
gene id: 1622118:Lupro_RS03930
uniprot id: A0A109RN51
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1622118:Lupro RS10830
gene id: 1622118:Lupro_RS10830
uniprot id: A0A0X8G7X7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1622118:Lupro RS06005
gene id: 1622118:Lupro_RS06005
uniprot id: A0A0X8G667
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

1622118:Lupro RS06895
gene id: 1622118:Lupro_RS06895
uniprot id: A0A0X8G6L2
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1622118:Lupro RS06945
gene id: 1622118:Lupro_RS06945
uniprot id: A0A0X8G8Z3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1622118:Lupro RS10615
gene id: 1622118:Lupro_RS10615
uniprot id: A0A0X8G7U5
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1622118:Lupro RS12810
gene id: 1622118:Lupro_RS12810
uniprot id: A0A110B8Q4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1622118:Lupro RS05360
gene id: 1622118:Lupro_RS05360
uniprot id: A0A109RNC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1622118:Lupro RS09065
gene id: 1622118:Lupro_RS09065
uniprot id: A0A109RQ05
names: Similarity
messages: Belongs to the peptidase S41A family.

1622118:Lupro RS10045
gene id: 1622118:Lupro_RS10045
uniprot id: A0A0X8G7M8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1622118:Lupro RS12465
gene id: 1622118:Lupro_RS12465
uniprot id: A0A0X8G8I7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

1622118:Lupro RS00625
gene id: 1622118:Lupro_RS00625
uniprot id: A0A0X8G4C6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1622118:Lupro RS09555
gene id: 1622118:Lupro_RS09555
uniprot id: A0A0X8G7H0
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1622118:Lupro RS07595
gene id: 1622118:Lupro_RS07595
uniprot id: A0A0X8G6T7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS06790
gene id: 1622118:Lupro_RS06790
uniprot id: A0A0X8G8X5
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

1622118:Lupro RS03400
gene id: 1622118:Lupro_RS03400
uniprot id: A0A0X8G5A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1622118:Lupro RS07330
gene id: 1622118:Lupro_RS07330
uniprot id: A0A120IEA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1622118:Lupro RS02385
gene id: 1622118:Lupro_RS02385
uniprot id: A0A120IE02
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1622118:Lupro RS12415
gene id: 1622118:Lupro_RS12415
uniprot id: A0A120IEK8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1622118:Lupro RS02470
gene id: 1622118:Lupro_RS02470
uniprot id: A0A109RNZ2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1622118:Lupro RS09600
gene id: 1622118:Lupro_RS09600
uniprot id: A0A120IEF5
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1622118:Lupro RS05130
gene id: 1622118:Lupro_RS05130
uniprot id: A0A120IE60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS12615
gene id: 1622118:Lupro_RS12615
uniprot id: A0A0X8G8M4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1622118:Lupro RS06305
gene id: 1622118:Lupro_RS06305
uniprot id: A0A0X8G6E1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1622118:Lupro RS03385
gene id: 1622118:Lupro_RS03385
uniprot id: A0A0X8G5A9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1622118:Lupro RS11495
gene id: 1622118:Lupro_RS11495
uniprot id: A0A109RP20
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1622118:Lupro RS11545
gene id: 1622118:Lupro_RS11545
uniprot id: A0A0X8G878
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1622118:Lupro RS05730
gene id: 1622118:Lupro_RS05730
uniprot id: A0A109RNB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1622118:Lupro RS07830
gene id: 1622118:Lupro_RS07830
uniprot id: A0A0X8G6V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1622118:Lupro RS08050
gene id: 1622118:Lupro_RS08050
uniprot id: A0A0X8G710
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1622118:Lupro RS12515
gene id: 1622118:Lupro_RS12515
uniprot id: A0A0X8G8H6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1622118:Lupro RS11020
gene id: 1622118:Lupro_RS11020
uniprot id: A0A0X8G803
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS00750
gene id: 1622118:Lupro_RS00750
uniprot id: A0A0X8G563
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1622118:Lupro RS11840
gene id: 1622118:Lupro_RS11840
uniprot id: A0A0X8G8F1
names: Similarity
messages: Belongs to the peptidase S24 family.

1622118:Lupro RS00350
gene id: 1622118:Lupro_RS00350
uniprot id: A0A120IDW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1622118:Lupro RS00705
gene id: 1622118:Lupro_RS00705
uniprot id: A0A0X8G4I0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1622118:Lupro RS05955
gene id: 1622118:Lupro_RS05955
uniprot id: A0A109RNR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1622118:Lupro RS09000
gene id: 1622118:Lupro_RS09000
uniprot id: A0A0X8G7D0
names: Similarity
messages: Belongs to the RelE toxin family.

1622118:Lupro RS02250
gene id: 1622118:Lupro_RS02250
uniprot id: A0A0X8G4Y3
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS08730
gene id: 1622118:Lupro_RS08730
uniprot id: A0A0X8G785
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1622118:Lupro RS04985
gene id: 1622118:Lupro_RS04985
uniprot id: A0A109RN97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1622118:Lupro RS11245
gene id: 1622118:Lupro_RS11245
uniprot id: A0A0X8G823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS01215
gene id: 1622118:Lupro_RS01215
uniprot id: A0A0X8G4K7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1622118:Lupro RS02150
gene id: 1622118:Lupro_RS02150
uniprot id: A0A109RMX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1622118:Lupro RS02215
gene id: 1622118:Lupro_RS02215
uniprot id: A0A109RNB1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1622118:Lupro RS04990
gene id: 1622118:Lupro_RS04990
uniprot id: A0A109RP89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1622118:Lupro RS08100
gene id: 1622118:Lupro_RS08100
uniprot id: A0A0X8G7Q4
names: Similarity
messages: Belongs to the BtpA family.

1622118:Lupro RS07990
gene id: 1622118:Lupro_RS07990
uniprot id: A0A0X8G6Z4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1622118:Lupro RS11555
gene id: 1622118:Lupro_RS11555
uniprot id: A0A0X8G890
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1622118:Lupro RS03455
gene id: 1622118:Lupro_RS03455
uniprot id: A0A109RN29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1622118:Lupro RS08930
gene id: 1622118:Lupro_RS08930
uniprot id: A0A0X8G783
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1622118:Lupro RS01350
gene id: 1622118:Lupro_RS01350
uniprot id: A0A0X8G5D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1622118:Lupro RS05735
gene id: 1622118:Lupro_RS05735
uniprot id: A0A109RNC9
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS10000
gene id: 1622118:Lupro_RS10000
uniprot id: A0A109RP81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1622118:Lupro RS11195
gene id: 1622118:Lupro_RS11195
uniprot id: A0A0X8G873
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1622118:Lupro RS04760
gene id: 1622118:Lupro_RS04760
uniprot id: A0A109RPG7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1622118:Lupro RS08515
gene id: 1622118:Lupro_RS08515
uniprot id: A0A120IED0
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS03565
gene id: 1622118:Lupro_RS03565
uniprot id: A0A0X8G5C7
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS06900
gene id: 1622118:Lupro_RS06900
uniprot id: A0A0X8G6K0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1622118:Lupro RS07170
gene id: 1622118:Lupro_RS07170
uniprot id: A0A109RPG9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1622118:Lupro RS03330
gene id: 1622118:Lupro_RS03330
uniprot id: A0A0X8G5D6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1622118:Lupro RS02615
gene id: 1622118:Lupro_RS02615
uniprot id: A0A120IE08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS04340
gene id: 1622118:Lupro_RS04340
uniprot id: A0A0X8G5P5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS12690
gene id: 1622118:Lupro_RS12690
uniprot id: A0A0X8G8N3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1622118:Lupro RS04560
gene id: 1622118:Lupro_RS04560
uniprot id: A0A0X8G6J1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1622118:Lupro RS07000
gene id: 1622118:Lupro_RS07000
uniprot id: A0A120IE98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1622118:Lupro RS10915
gene id: 1622118:Lupro_RS10915
uniprot id: A0A0X8G845
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1622118:Lupro RS10245
gene id: 1622118:Lupro_RS10245
uniprot id: A0A0X8G7U4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1622118:Lupro RS09655
gene id: 1622118:Lupro_RS09655
uniprot id: A0A0X8G7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1622118:Lupro RS04140
gene id: 1622118:Lupro_RS04140
uniprot id: A0A0X8G5K8
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS09375
gene id: 1622118:Lupro_RS09375
uniprot id: A0A120IEE8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1622118:Lupro RS05785
gene id: 1622118:Lupro_RS05785
uniprot id: A0A0X8G674
names: Similarity
messages: Belongs to the peptidase S41A family.

1622118:Lupro RS10035
gene id: 1622118:Lupro_RS10035
uniprot id: A0A0X8G7M7
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS04700
gene id: 1622118:Lupro_RS04700
uniprot id: A0A0X8G5U8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1622118:Lupro RS10335
gene id: 1622118:Lupro_RS10335
uniprot id: A0A120IEG9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS03750
gene id: 1622118:Lupro_RS03750
uniprot id: A0A0X8G5H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1622118:Lupro RS07785
gene id: 1622118:Lupro_RS07785
uniprot id: A0A0X8G7L7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1622118:Lupro RS05275
gene id: 1622118:Lupro_RS05275
uniprot id: A0A0X8G5Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1622118:Lupro RS11535
gene id: 1622118:Lupro_RS11535
uniprot id: A0A0X8G860
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1622118:Lupro RS08350
gene id: 1622118:Lupro_RS08350
uniprot id: A0A109RNP6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1622118:Lupro RS01730
gene id: 1622118:Lupro_RS01730
uniprot id: A0A0X8G4T7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1622118:Lupro RS10465
gene id: 1622118:Lupro_RS10465
uniprot id: A0A0X8G7W3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1622118:Lupro RS05180
gene id: 1622118:Lupro_RS05180
uniprot id: A0A0X8G5W9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1622118:Lupro RS05340
gene id: 1622118:Lupro_RS05340
uniprot id: A0A0X8G631
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1622118:Lupro RS10330
gene id: 1622118:Lupro_RS10330
uniprot id: A0A0X8G8J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1622118:Lupro RS05025
gene id: 1622118:Lupro_RS05025
uniprot id: A0A0X8G5Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1622118:Lupro RS10655
gene id: 1622118:Lupro_RS10655
uniprot id: A0A120IEH4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1622118:Lupro RS12215
gene id: 1622118:Lupro_RS12215
uniprot id: A0A0X8G8F6
names: Similarity
messages: Belongs to the SusD family.

1622118:Lupro RS04805
gene id: 1622118:Lupro_RS04805
uniprot id: A0A0X8G5T1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1622118:Lupro RS08135
gene id: 1622118:Lupro_RS08135
uniprot id: A0A0X8G711
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1622118:Lupro RS00700
gene id: 1622118:Lupro_RS00700
uniprot id: A0A0X8G4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1622118:Lupro RS03885
gene id: 1622118:Lupro_RS03885
uniprot id: A0A0X8G5G5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1622118:Lupro RS03410
gene id: 1622118:Lupro_RS03410
uniprot id: A0A0X8G5E3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1622118:Lupro RS00025
gene id: 1622118:Lupro_RS00025
uniprot id: A0A120IDV9
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1622118:Lupro RS03475
gene id: 1622118:Lupro_RS03475
uniprot id: A0A0X8G5B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1622118:Lupro RS10135
gene id: 1622118:Lupro_RS10135
uniprot id: A0A0X8G7P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

1622118:Lupro RS12800
gene id: 1622118:Lupro_RS12800
uniprot id: A0A0X8G8N2
names: Similarity
messages: Belongs to the pirin family.

1622118:Lupro RS02485
gene id: 1622118:Lupro_RS02485
uniprot id: A0A0X8G509
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1622118:Lupro RS06785
gene id: 1622118:Lupro_RS06785
uniprot id: A0A0X8G6I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1622118:Lupro RS08475
gene id: 1622118:Lupro_RS08475
uniprot id: A0A0X8G723
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1622118:Lupro RS10250
gene id: 1622118:Lupro_RS10250
uniprot id: A0A109RP91
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1622118:Lupro RS12010
gene id: 1622118:Lupro_RS12010
uniprot id: A0A0X8G8B9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1622118:Lupro RS03575
gene id: 1622118:Lupro_RS03575
uniprot id: A0A0X8G5G8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1622118:Lupro RS07140
gene id: 1622118:Lupro_RS07140
uniprot id: A0A0X8G6P3
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1622118:Lupro RS10825
gene id: 1622118:Lupro_RS10825
uniprot id: A0A120IEI0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1622118:Lupro RS08360
gene id: 1622118:Lupro_RS08360
uniprot id: A0A109RPM0
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1622118:Lupro RS03835
gene id: 1622118:Lupro_RS03835
uniprot id: A0A0X8G5H5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1622118:Lupro RS00640
gene id: 1622118:Lupro_RS00640
uniprot id: A0A0X8G4C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1622118:Lupro RS12685
gene id: 1622118:Lupro_RS12685
uniprot id: A0A0X8G8J4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS05720
gene id: 1622118:Lupro_RS05720
uniprot id: A0A109RNQ2
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1622118:Lupro RS11255
gene id: 1622118:Lupro_RS11255
uniprot id: A0A0X8G832
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1622118:Lupro RS02065
gene id: 1622118:Lupro_RS02065
uniprot id: A0A120IE00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1622118:Lupro RS12675
gene id: 1622118:Lupro_RS12675
uniprot id: A0A0X8G8J8
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS11570
gene id: 1622118:Lupro_RS11570
uniprot id: A0A0X8G902
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS12255
gene id: 1622118:Lupro_RS12255
uniprot id: A0A109RQC6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1622118:Lupro RS05090
gene id: 1622118:Lupro_RS05090
uniprot id: A0A0X8G5V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1622118:Lupro RS04575
gene id: 1622118:Lupro_RS04575
uniprot id: A0A120IE46
names: Similarity
messages: Belongs to the UPF0246 family.

1622118:Lupro RS03550
gene id: 1622118:Lupro_RS03550
uniprot id: A0A0X8G5D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1622118:Lupro RS08210
gene id: 1622118:Lupro_RS08210
uniprot id: A0A0X8G6Y9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1622118:Lupro RS04425
gene id: 1622118:Lupro_RS04425
uniprot id: A0A0X8G5M7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1622118:Lupro RS03840
gene id: 1622118:Lupro_RS03840
uniprot id: A0A109RN69
names: Similarity
messages: Belongs to the CinA family.

1622118:Lupro RS02125
gene id: 1622118:Lupro_RS02125
uniprot id: A0A109RN07
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS11080
gene id: 1622118:Lupro_RS11080
uniprot id: A0A0X8G806
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1622118:Lupro RS09425
gene id: 1622118:Lupro_RS09425
uniprot id: A0A109RNT4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1622118:Lupro RS12915
gene id: 1622118:Lupro_RS12915
uniprot id: A0A109RPB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1622118:Lupro RS04950
gene id: 1622118:Lupro_RS04950
uniprot id: A0A0X8G5Y6
names: Similarity
messages: Belongs to the citrate synthase family.

1622118:Lupro RS13030
gene id: 1622118:Lupro_RS13030
uniprot id: A0A0X8G8S0
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1622118:Lupro RS07150
gene id: 1622118:Lupro_RS07150
uniprot id: A0A109RNW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1622118:Lupro RS07995
gene id: 1622118:Lupro_RS07995
uniprot id: A0A0X8G708
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS01635
gene id: 1622118:Lupro_RS01635
uniprot id: A0A0X8G4R6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS04130
gene id: 1622118:Lupro_RS04130
uniprot id: A0A0X8G5M8
names: Similarity
messages: Belongs to the UPF0047 family.

1622118:Lupro RS09285
gene id: 1622118:Lupro_RS09285
uniprot id: A0A109RNS8
names: Similarity
messages: Belongs to the pyruvate kinase family.

1622118:Lupro RS04400
gene id: 1622118:Lupro_RS04400
uniprot id: A0A109RNB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1622118:Lupro RS09500
gene id: 1622118:Lupro_RS09500
uniprot id: A0A0X8G7I9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1622118:Lupro RS05230
gene id: 1622118:Lupro_RS05230
uniprot id: A0A109RPI9
names: Similarity
messages: Belongs to the UPF0758 family.

1622118:Lupro RS05615
gene id: 1622118:Lupro_RS05615
uniprot id: A0A0X8G654
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS05525
gene id: 1622118:Lupro_RS05525
uniprot id: A0A0X8G638
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1622118:Lupro RS07135
gene id: 1622118:Lupro_RS07135
uniprot id: A0A0X8G6P2
names: Similarity
messages: Belongs to the HypD family.

1622118:Lupro RS05450
gene id: 1622118:Lupro_RS05450
uniprot id: A0A109RNP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1622118:Lupro RS10510
gene id: 1622118:Lupro_RS10510
uniprot id: A0A109RPW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1622118:Lupro RS12020
gene id: 1622118:Lupro_RS12020
uniprot id: A0A0X8G8D3
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1622118:Lupro RS06930
gene id: 1622118:Lupro_RS06930
uniprot id: A0A109RPQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1622118:Lupro RS05410
gene id: 1622118:Lupro_RS05410
uniprot id: A0A0X8G5Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1622118:Lupro RS01750
gene id: 1622118:Lupro_RS01750
uniprot id: A0A0X8G4T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS09310
gene id: 1622118:Lupro_RS09310
uniprot id: A0A0X8G7E8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS01720
gene id: 1622118:Lupro_RS01720
uniprot id: A0A0X8G4R8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1622118:Lupro RS10255
gene id: 1622118:Lupro_RS10255
uniprot id: A0A0X8G8I1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1622118:Lupro RS08235
gene id: 1622118:Lupro_RS08235
uniprot id: A0A0X8G735
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1622118:Lupro RS08455
gene id: 1622118:Lupro_RS08455
uniprot id: A0A0X8G718
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1622118:Lupro RS07635
gene id: 1622118:Lupro_RS07635
uniprot id: A0A0X8G7J6
names: Similarity
messages: Belongs to the SCO1/2 family.

1622118:Lupro RS12300
gene id: 1622118:Lupro_RS12300
uniprot id: A0A0X8G8H3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1622118:Lupro RS02375
gene id: 1622118:Lupro_RS02375
uniprot id: A0A109RN16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
messages: Golgi apparatus
messages: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
messages: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
messages: In the N-terminal section; belongs to the formiminotransferase family.
messages: centriole

1622118:Lupro RS02420
gene id: 1622118:Lupro_RS02420
uniprot id: A0A0X8G4Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1622118:Lupro RS12780
gene id: 1622118:Lupro_RS12780
uniprot id: A0A0X8G8K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1622118:Lupro RS06350
gene id: 1622118:Lupro_RS06350
uniprot id: A0A109RNG2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1622118:Lupro RS10385
gene id: 1622118:Lupro_RS10385
uniprot id: A0A0X8G7V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1622118:Lupro RS02440
gene id: 1622118:Lupro_RS02440
uniprot id: A0A0X8G518
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS12160
gene id: 1622118:Lupro_RS12160
uniprot id: A0A120IEK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1622118:Lupro RS10725
gene id: 1622118:Lupro_RS10725
uniprot id: A0A109RPA9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1622118:Lupro RS02915
gene id: 1622118:Lupro_RS02915
uniprot id: A0A0X8G572
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1622118:Lupro RS04970
gene id: 1622118:Lupro_RS04970
uniprot id: A0A109RNM1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1622118:Lupro RS09800
gene id: 1622118:Lupro_RS09800
uniprot id: A0A0X8G7L1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1622118:Lupro RS00045
gene id: 1622118:Lupro_RS00045
uniprot id: A0A0X8G457
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1622118:Lupro RS09590
gene id: 1622118:Lupro_RS09590
uniprot id: A0A0X8G897
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS02480
gene id: 1622118:Lupro_RS02480
uniprot id: A0A0X8G507
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1622118:Lupro RS10460
gene id: 1622118:Lupro_RS10460
uniprot id: A0A0X8G7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1622118:Lupro RS08240
gene id: 1622118:Lupro_RS08240
uniprot id: A0A0X8G8Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1622118:Lupro RS00440
gene id: 1622118:Lupro_RS00440
uniprot id: A0A109RP23
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1622118:Lupro RS02655
gene id: 1622118:Lupro_RS02655
uniprot id: A0A0X8G524
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1622118:Lupro RS08250
gene id: 1622118:Lupro_RS08250
uniprot id: A0A0X8G738
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1622118:Lupro RS11745
gene id: 1622118:Lupro_RS11745
uniprot id: A0A109RQA7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS04125
gene id: 1622118:Lupro_RS04125
uniprot id: A0A0X8G5L3
names: Similarity
messages: Belongs to the peptidase A31 family.

1622118:Lupro RS08435
gene id: 1622118:Lupro_RS08435
uniprot id: A0A120IEC8
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS08110
gene id: 1622118:Lupro_RS08110
uniprot id: A0A109RNM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1622118:Lupro RS02210
gene id: 1622118:Lupro_RS02210
uniprot id: A0A0X8G4Y0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1622118:Lupro RS00380
gene id: 1622118:Lupro_RS00380
uniprot id: A0A0X8G4F0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1622118:Lupro RS08325
gene id: 1622118:Lupro_RS08325
uniprot id: A0A0X8G749
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1622118:Lupro RS11305
gene id: 1622118:Lupro_RS11305
uniprot id: A0A0X8G8X0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1622118:Lupro RS09215
gene id: 1622118:Lupro_RS09215
uniprot id: A0A109RNW1
names: Similarity
messages: Belongs to the UPF0102 family.

1622118:Lupro RS01400
gene id: 1622118:Lupro_RS01400
uniprot id: A0A0X8G4N3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1622118:Lupro RS11400
gene id: 1622118:Lupro_RS11400
uniprot id: A0A0X8G8X9
names: Similarity
messages: Belongs to the arginase family.

1622118:Lupro RS07175
gene id: 1622118:Lupro_RS07175
uniprot id: A0A109RPS3
names: Similarity
messages: Belongs to the HupF/HypC family.

1622118:Lupro RS11590
gene id: 1622118:Lupro_RS11590
uniprot id: A0A120IEJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1622118:Lupro RS06300
gene id: 1622118:Lupro_RS06300
uniprot id: A0A0X8G696
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1622118:Lupro RS12385
gene id: 1622118:Lupro_RS12385
uniprot id: A0A0X8G8I3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1622118:Lupro RS03965
gene id: 1622118:Lupro_RS03965
uniprot id: A0A0X8G5H3
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS05000
gene id: 1622118:Lupro_RS05000
uniprot id: A0A0X8G5U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1622118:Lupro RS08180
gene id: 1622118:Lupro_RS08180
uniprot id: A0A0X8G8V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1622118:Lupro RS09660
gene id: 1622118:Lupro_RS09660
uniprot id: A0A0X8G7M2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1622118:Lupro RS10770
gene id: 1622118:Lupro_RS10770
uniprot id: A0A0X8G7W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1622118:Lupro RS08145
gene id: 1622118:Lupro_RS08145
uniprot id: A0A0X8G6Y7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1622118:Lupro RS01575
gene id: 1622118:Lupro_RS01575
uniprot id: A0A0X8G4P6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1622118:Lupro RS01910
gene id: 1622118:Lupro_RS01910
uniprot id: A0A0X8G4U4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1622118:Lupro RS01345
gene id: 1622118:Lupro_RS01345
uniprot id: A0A109RMX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1622118:Lupro RS03735
gene id: 1622118:Lupro_RS03735
uniprot id: A0A0X8G5I5
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS12150
gene id: 1622118:Lupro_RS12150
uniprot id: A0A0X8G942
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1622118:Lupro RS11000
gene id: 1622118:Lupro_RS11000
uniprot id: A0A0X8G7Z7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1622118:Lupro RS08625
gene id: 1622118:Lupro_RS08625
uniprot id: A0A0X8G766
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1622118:Lupro RS03650
gene id: 1622118:Lupro_RS03650
uniprot id: A0A0X8G5E6
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS13715
gene id: 1622118:Lupro_RS13715
uniprot id: A0A109RP37
names: Similarity
messages: Belongs to the peptidase M4 family.

1622118:Lupro RS02460
gene id: 1622118:Lupro_RS02460
uniprot id: A0A109RMX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1622118:Lupro RS03940
gene id: 1622118:Lupro_RS03940
uniprot id: A0A109RPE2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1622118:Lupro RS10395
gene id: 1622118:Lupro_RS10395
uniprot id: A0A0X8G7U9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1622118:Lupro RS05455
gene id: 1622118:Lupro_RS05455
uniprot id: A0A0X8G6V1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1622118:Lupro RS07825
gene id: 1622118:Lupro_RS07825
uniprot id: A0A0X8G6U2
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS09025
gene id: 1622118:Lupro_RS09025
uniprot id: A0A0X8G7C2
names: Similarity
messages: Belongs to the glutamate synthase family.

1622118:Lupro RS06295
gene id: 1622118:Lupro_RS06295
uniprot id: A0A120IE86
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1622118:Lupro RS12235
gene id: 1622118:Lupro_RS12235
uniprot id: A0A0X8G951
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1622118:Lupro RS07400
gene id: 1622118:Lupro_RS07400
uniprot id: A0A109RNX9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS07950
gene id: 1622118:Lupro_RS07950
uniprot id: A0A120IEB7
names: Similarity
messages: Belongs to the group II decarboxylase family.

1622118:Lupro RS12240
gene id: 1622118:Lupro_RS12240
uniprot id: A0A109RP58
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1622118:Lupro RS07385
gene id: 1622118:Lupro_RS07385
uniprot id: A0A0X8G6R9
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS01795
gene id: 1622118:Lupro_RS01795
uniprot id: A0A120IDZ5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1622118:Lupro RS11235
gene id: 1622118:Lupro_RS11235
uniprot id: A0A0X8G826
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1622118:Lupro RS02570
gene id: 1622118:Lupro_RS02570
uniprot id: A0A0X8G511
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1622118:Lupro RS07770
gene id: 1622118:Lupro_RS07770
uniprot id: A0A0X8G6Y1
names: Similarity
messages: Belongs to the aspartokinase family.

1622118:Lupro RS06265
gene id: 1622118:Lupro_RS06265
uniprot id: A0A0X8G6B7
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS06315
gene id: 1622118:Lupro_RS06315
uniprot id: A0A0X8G699
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1622118:Lupro RS04355
gene id: 1622118:Lupro_RS04355
uniprot id: A0A0X8G5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1622118:Lupro RS07545
gene id: 1622118:Lupro_RS07545
uniprot id: A0A0X8G6U5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1622118:Lupro RS01740
gene id: 1622118:Lupro_RS01740
uniprot id: A0A0X8G4S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1622118:Lupro RS01255
gene id: 1622118:Lupro_RS01255
uniprot id: A0A0X8G4L6
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1622118:Lupro RS07905
gene id: 1622118:Lupro_RS07905
uniprot id: A0A0X8G6W0
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS09220
gene id: 1622118:Lupro_RS09220
uniprot id: A0A109RNS3
names: Similarity
messages: Belongs to the peptidase S66 family.

1622118:Lupro RS01005
gene id: 1622118:Lupro_RS01005
uniprot id: A0A0X8G4K4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1622118:Lupro RS05075
gene id: 1622118:Lupro_RS05075
uniprot id: A0A0X8G5U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1622118:Lupro RS09985
gene id: 1622118:Lupro_RS09985
uniprot id: A0A0X8G7P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1622118:Lupro RS11045
gene id: 1622118:Lupro_RS11045
uniprot id: A0A109RP25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1622118:Lupro RS08565
gene id: 1622118:Lupro_RS08565
uniprot id: A0A0X8G771
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1622118:Lupro RS07145
gene id: 1622118:Lupro_RS07145
uniprot id: A0A0X8G6N1
names: Similarity
messages: Belongs to the peptidase A31 family.

1622118:Lupro RS02135
gene id: 1622118:Lupro_RS02135
uniprot id: A0A120IE01
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1622118:Lupro RS04480
gene id: 1622118:Lupro_RS04480
uniprot id: A0A109RNK3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1622118:Lupro RS11665
gene id: 1622118:Lupro_RS11665
uniprot id: A0A109RP28
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1622118:Lupro RS04490
gene id: 1622118:Lupro_RS04490
uniprot id: A0A109RN66
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1622118:Lupro RS06810
gene id: 1622118:Lupro_RS06810
uniprot id: A0A0X8G6K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1622118:Lupro RS03020
gene id: 1622118:Lupro_RS03020
uniprot id: A0A120IE18
names: Similarity
messages: Belongs to the YoeB family.

1622118:Lupro RS07570
gene id: 1622118:Lupro_RS07570
uniprot id: A0A109RNQ9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1622118:Lupro RS05065
gene id: 1622118:Lupro_RS05065
uniprot id: A0A120IE59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1622118:Lupro RS05435
gene id: 1622118:Lupro_RS05435
uniprot id: A0A0X8G635
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS10850
gene id: 1622118:Lupro_RS10850
uniprot id: A0A0X8G7Y7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

1622118:Lupro RS06190
gene id: 1622118:Lupro_RS06190
uniprot id: A0A0X8G6A6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1622118:Lupro RS01240
gene id: 1622118:Lupro_RS01240
uniprot id: A0A0X8G4M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1622118:Lupro RS08550
gene id: 1622118:Lupro_RS08550
uniprot id: A0A109RPA6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1622118:Lupro RS10450
gene id: 1622118:Lupro_RS10450
uniprot id: A0A0X8G7T0
names: Similarity
messages: Belongs to the universal stress protein A family.

1622118:Lupro RS12470
gene id: 1622118:Lupro_RS12470
uniprot id: A0A0X8G8J3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1622118:Lupro RS11575
gene id: 1622118:Lupro_RS11575
uniprot id: A0A120IEJ4
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

1622118:Lupro RS06530
gene id: 1622118:Lupro_RS06530
uniprot id: A0A120IE87
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1622118:Lupro RS01900
gene id: 1622118:Lupro_RS01900
uniprot id: A0A109RN12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS02490
gene id: 1622118:Lupro_RS02490
uniprot id: A0A0X8G521
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1622118:Lupro RS10400
gene id: 1622118:Lupro_RS10400
uniprot id: A0A0X8G7W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1622118:Lupro RS06435
gene id: 1622118:Lupro_RS06435
uniprot id: A0A109RNE9
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1622118:Lupro RS04600
gene id: 1622118:Lupro_RS04600
uniprot id: A0A0X8G5P6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1622118:Lupro RS04245
gene id: 1622118:Lupro_RS04245
uniprot id: A0A0X8G5K4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1622118:Lupro RS00955
gene id: 1622118:Lupro_RS00955
uniprot id: A0A109RMT3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1622118:Lupro RS02115
gene id: 1622118:Lupro_RS02115
uniprot id: A0A0X8G4X7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1622118:Lupro RS06570
gene id: 1622118:Lupro_RS06570
uniprot id: A0A0X8G6G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1622118:Lupro RS08575
gene id: 1622118:Lupro_RS08575
uniprot id: A0A0X8G776
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1622118:Lupro RS12510
gene id: 1622118:Lupro_RS12510
uniprot id: A0A0X8G8Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1622118:Lupro RS11630
gene id: 1622118:Lupro_RS11630
uniprot id: A0A0X8G8A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1622118:Lupro RS01775
gene id: 1622118:Lupro_RS01775
uniprot id: A0A109RMZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1622118:Lupro RS01860
gene id: 1622118:Lupro_RS01860
uniprot id: A0A109RMZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS03460
gene id: 1622118:Lupro_RS03460
uniprot id: A0A109RP31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1622118:Lupro RS09950
gene id: 1622118:Lupro_RS09950
uniprot id: A0A0X8G7L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1622118:Lupro RS11105
gene id: 1622118:Lupro_RS11105
uniprot id: A0A0X8G851
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1622118:Lupro RS06795
gene id: 1622118:Lupro_RS06795
uniprot id: A0A0X8G6F9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1622118:Lupro RS08090
gene id: 1622118:Lupro_RS08090
uniprot id: A0A0X8G8V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1622118:Lupro RS03990
gene id: 1622118:Lupro_RS03990
uniprot id: A0A0X8G5J8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1622118:Lupro RS02575
gene id: 1622118:Lupro_RS02575
uniprot id: A0A0X8G530
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1622118:Lupro RS01165
gene id: 1622118:Lupro_RS01165
uniprot id: A0A0X8G4M4
names: Subcellular Location Annotation
messages: Secreted

1622118:Lupro RS00560
gene id: 1622118:Lupro_RS00560
uniprot id: A0A0X8G4B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1622118:Lupro RS04005
gene id: 1622118:Lupro_RS04005
uniprot id: A0A0X8G6D0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1622118:Lupro RS08045
gene id: 1622118:Lupro_RS08045
uniprot id: A0A0X8G6X0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1622118:Lupro RS10635
gene id: 1622118:Lupro_RS10635
uniprot id: A0A0X8G7X6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1622118:Lupro RS10910
gene id: 1622118:Lupro_RS10910
uniprot id: A0A0X8G7Y5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1622118:Lupro RS10525
gene id: 1622118:Lupro_RS10525
uniprot id: A0A0X8G7Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1622118:Lupro RS05080
gene id: 1622118:Lupro_RS05080
uniprot id: A0A0X8G5Y2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1622118:Lupro RS05420
gene id: 1622118:Lupro_RS05420
uniprot id: A0A0X8G641
names: Similarity
messages: Belongs to the TrpF family.

1622118:Lupro RS09270
gene id: 1622118:Lupro_RS09270
uniprot id: A0A109RP55
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1622118:Lupro RS10865
gene id: 1622118:Lupro_RS10865
uniprot id: A0A0X8G807
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS00240
gene id: 1622118:Lupro_RS00240
uniprot id: A0A0X8G480
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1622118:Lupro RS06080
gene id: 1622118:Lupro_RS06080
uniprot id: A0A0X8G6A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1622118:Lupro RS01160
gene id: 1622118:Lupro_RS01160
uniprot id: A0A0X8G4L1
names: Similarity
messages: Belongs to the threonine aldolase family.

1622118:Lupro RS10585
gene id: 1622118:Lupro_RS10585
uniprot id: A0A120IEH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1622118:Lupro RS07655
gene id: 1622118:Lupro_RS07655
uniprot id: A0A109RPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1622118:Lupro RS01810
gene id: 1622118:Lupro_RS01810
uniprot id: A0A0X8G4T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1622118:Lupro RS10145
gene id: 1622118:Lupro_RS10145
uniprot id: A0A0X8G7S7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1622118:Lupro RS07355
gene id: 1622118:Lupro_RS07355
uniprot id: A0A0X8G6S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1622118:Lupro RS01665
gene id: 1622118:Lupro_RS01665
uniprot id: A0A0X8G4S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1622118:Lupro RS01840
gene id: 1622118:Lupro_RS01840
uniprot id: A0A0X8G4U5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1622118:Lupro RS08225
gene id: 1622118:Lupro_RS08225
uniprot id: A0A0X8G6Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1622118:Lupro RS05395
gene id: 1622118:Lupro_RS05395
uniprot id: A0A0X8G625
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1622118:Lupro RS00325
gene id: 1622118:Lupro_RS00325
uniprot id: A0A0X8G488
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1622118:Lupro RS00975
gene id: 1622118:Lupro_RS00975
uniprot id: A0A0X8G4H8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1622118:Lupro RS06410
gene id: 1622118:Lupro_RS06410
uniprot id: A0A0X8G6E9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1622118:Lupro RS03915
gene id: 1622118:Lupro_RS03915
uniprot id: A0A109RNI5
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS05235
gene id: 1622118:Lupro_RS05235
uniprot id: A0A0X8G5W8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1622118:Lupro RS06915
gene id: 1622118:Lupro_RS06915
uniprot id: A0A109RNH5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1622118:Lupro RS06775
gene id: 1622118:Lupro_RS06775
uniprot id: A0A0X8G6F5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS08915
gene id: 1622118:Lupro_RS08915
uniprot id: A0A0X8G787
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS01225
gene id: 1622118:Lupro_RS01225
uniprot id: A0A0X8G4K9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1622118:Lupro RS06965
gene id: 1622118:Lupro_RS06965
uniprot id: A0A0X8G6M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1622118:Lupro RS11030
gene id: 1622118:Lupro_RS11030
uniprot id: A0A0X8G824
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1622118:Lupro RS07240
gene id: 1622118:Lupro_RS07240
uniprot id: A0A120IEA6
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1622118:Lupro RS09845
gene id: 1622118:Lupro_RS09845
uniprot id: A0A120IEG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1622118:Lupro RS05740
gene id: 1622118:Lupro_RS05740
uniprot id: A0A109RPB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1622118:Lupro RS05150
gene id: 1622118:Lupro_RS05150
uniprot id: A0A0X8G8Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS05115
gene id: 1622118:Lupro_RS05115
uniprot id: A0A0X8G5X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1622118:Lupro RS02430
gene id: 1622118:Lupro_RS02430
uniprot id: A0A0X8G516
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1622118:Lupro RS00810
gene id: 1622118:Lupro_RS00810
uniprot id: A0A0X8G4I3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1622118:Lupro RS11170
gene id: 1622118:Lupro_RS11170
uniprot id: A0A0X8G811
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1622118:Lupro RS07465
gene id: 1622118:Lupro_RS07465
uniprot id: A0A0X8G6S7
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS06495
gene id: 1622118:Lupro_RS06495
uniprot id: A0A0X8G6G1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1622118:Lupro RS12035
gene id: 1622118:Lupro_RS12035
uniprot id: A0A109RP60
names: Function
messages: May be involved in the biogenesis of curli organelles.

1622118:Lupro RS07070
gene id: 1622118:Lupro_RS07070
uniprot id: A0A0X8G7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1622118:Lupro RS03720
gene id: 1622118:Lupro_RS03720
uniprot id: A0A0X8G5H9
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1622118:Lupro RS00075
gene id: 1622118:Lupro_RS00075
uniprot id: A0A109RMR9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1622118:Lupro RS04565
gene id: 1622118:Lupro_RS04565
uniprot id: A0A120IE48
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1622118:Lupro RS00220
gene id: 1622118:Lupro_RS00220
uniprot id: A0A0X8G477
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1622118:Lupro RS11290
gene id: 1622118:Lupro_RS11290
uniprot id: A0A0X8G883
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS11095
gene id: 1622118:Lupro_RS11095
uniprot id: A0A0X8G802
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1622118:Lupro RS07620
gene id: 1622118:Lupro_RS07620
uniprot id: A0A0X8G6V5
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS01540
gene id: 1622118:Lupro_RS01540
uniprot id: A0A120IDY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS10855
gene id: 1622118:Lupro_RS10855
uniprot id: A0A0X8G818
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1622118:Lupro RS00005
gene id: 1622118:Lupro_RS00005
uniprot id: A0A0X8G4Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1622118:Lupro RS01990
gene id: 1622118:Lupro_RS01990
uniprot id: A0A109RNX6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1622118:Lupro RS07805
gene id: 1622118:Lupro_RS07805
uniprot id: A0A109RNK8
names: Similarity
messages: Belongs to the SufE family.

1622118:Lupro RS00110
gene id: 1622118:Lupro_RS00110
uniprot id: A0A0X8G8P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1622118:Lupro RS03875
gene id: 1622118:Lupro_RS03875
uniprot id: A0A0X8G5I2
names: Similarity
messages: Belongs to the peptidase C1 family.

1622118:Lupro RS01390
gene id: 1622118:Lupro_RS01390
uniprot id: A0A0X8G4P7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1622118:Lupro RS11885
gene id: 1622118:Lupro_RS11885
uniprot id: A0A0X8G923
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1622118:Lupro RS05780
gene id: 1622118:Lupro_RS05780
uniprot id: A0A0X8G668
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1622118:Lupro RS07750
gene id: 1622118:Lupro_RS07750
uniprot id: A0A0X8G6T0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1622118:Lupro RS04630
gene id: 1622118:Lupro_RS04630
uniprot id: A0A0X8G8T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1622118:Lupro RS01520
gene id: 1622118:Lupro_RS01520
uniprot id: A0A0X8G5F7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1622118:Lupro RS01125
gene id: 1622118:Lupro_RS01125
uniprot id: A0A109RMT2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1622118:Lupro RS00205
gene id: 1622118:Lupro_RS00205
uniprot id: A0A0X8G4A4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1622118:Lupro RS05330
gene id: 1622118:Lupro_RS05330
uniprot id: A0A0X8G5Y0
names: Similarity
messages: Belongs to the SusD family.

1622118:Lupro RS03280
gene id: 1622118:Lupro_RS03280
uniprot id: A0A120IE25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1622118:Lupro RS10520
gene id: 1622118:Lupro_RS10520
uniprot id: A0A0X8G7T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1622118:Lupro RS12015
gene id: 1622118:Lupro_RS12015
uniprot id: A0A0X8G8F3
names: Similarity
messages: Belongs to the CsgA/CsgB family.

1622118:Lupro RS12070
gene id: 1622118:Lupro_RS12070
uniprot id: A0A0X8G8I0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1622118:Lupro RS01310
gene id: 1622118:Lupro_RS01310
uniprot id: A0A0X8G4M2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS03470
gene id: 1622118:Lupro_RS03470
uniprot id: A0A0X8G5C0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1622118:Lupro RS00060
gene id: 1622118:Lupro_RS00060
uniprot id: A0A0X8G449
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1622118:Lupro RS06180
gene id: 1622118:Lupro_RS06180
uniprot id: A0A0X8G6B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1622118:Lupro RS06400
gene id: 1622118:Lupro_RS06400
uniprot id: A0A0X8G6C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1622118:Lupro RS05070
gene id: 1622118:Lupro_RS05070
uniprot id: A0A120IE57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1622118:Lupro RS13060
gene id: 1622118:Lupro_RS13060
uniprot id: A0A0X8G9E2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1622118:Lupro RS01130
gene id: 1622118:Lupro_RS01130
uniprot id: A0A0X8G4K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1622118:Lupro RS06640
gene id: 1622118:Lupro_RS06640
uniprot id: A0A0X8G6J0
names: Similarity
messages: Belongs to the Skp family.

1622118:Lupro RS03370
gene id: 1622118:Lupro_RS03370
uniprot id: A0A109RN26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1622118:Lupro RS08630
gene id: 1622118:Lupro_RS08630
uniprot id: A0A0X8G746
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1622118:Lupro RS11785
gene id: 1622118:Lupro_RS11785
uniprot id: A0A0X8G8A7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1622118:Lupro RS07060
gene id: 1622118:Lupro_RS07060
uniprot id: A0A0X8G6M0
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS10835
gene id: 1622118:Lupro_RS10835
uniprot id: A0A0X8G828
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1622118:Lupro RS04025
gene id: 1622118:Lupro_RS04025
uniprot id: A0A120IE38
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1622118:Lupro RS13075
gene id: 1622118:Lupro_RS13075
uniprot id: A0A120IEM4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1622118:Lupro RS11725
gene id: 1622118:Lupro_RS11725
uniprot id: A0A0X8G913
names: Similarity
messages: Belongs to the peptidase S8 family.

1622118:Lupro RS08500
gene id: 1622118:Lupro_RS08500
uniprot id: A0A0X8G743
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

1622118:Lupro RS12480
gene id: 1622118:Lupro_RS12480
uniprot id: A0A109RPH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1622118:Lupro RS09225
gene id: 1622118:Lupro_RS09225
uniprot id: A0A0X8G7C4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1622118:Lupro RS04675
gene id: 1622118:Lupro_RS04675
uniprot id: A0A0X8G8T5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1622118:Lupro RS09030
gene id: 1622118:Lupro_RS09030
uniprot id: A0A0X8G7C9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS05355
gene id: 1622118:Lupro_RS05355
uniprot id: A0A0X8G603
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1622118:Lupro RS00140
gene id: 1622118:Lupro_RS00140
uniprot id: A0A0X8G494
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1622118:Lupro RS06970
gene id: 1622118:Lupro_RS06970
uniprot id: A0A0X8G6M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1622118:Lupro RS05095
gene id: 1622118:Lupro_RS05095
uniprot id: A0A0X8G5W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1622118:Lupro RS12390
gene id: 1622118:Lupro_RS12390
uniprot id: A0A0X8G8K9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1622118:Lupro RS00745
gene id: 1622118:Lupro_RS00745
uniprot id: A0A0X8G8S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1622118:Lupro RS12495
gene id: 1622118:Lupro_RS12495
uniprot id: A0A109RP66
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1622118:Lupro RS05300
gene id: 1622118:Lupro_RS05300
uniprot id: A0A120IE66
names: Subunit
messages: Monomer.

1622118:Lupro RS07280
gene id: 1622118:Lupro_RS07280
uniprot id: A0A0X8G6M9
names: Similarity
messages: Belongs to the MoaD family.

1622118:Lupro RS09125
gene id: 1622118:Lupro_RS09125
uniprot id: A0A0X8G834
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS02300
gene id: 1622118:Lupro_RS02300
uniprot id: A0A0X8G5Q9
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

1622118:Lupro RS08750
gene id: 1622118:Lupro_RS08750
uniprot id: A0A109RNW0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1622118:Lupro RS04205
gene id: 1622118:Lupro_RS04205
uniprot id: A0A109RN63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1622118:Lupro RS12435
gene id: 1622118:Lupro_RS12435
uniprot id: A0A0X8G8G6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS11040
gene id: 1622118:Lupro_RS11040
uniprot id: A0A0X8G855
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS06385
gene id: 1622118:Lupro_RS06385
uniprot id: A0A0X8G6E5
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1622118:Lupro RS01150
gene id: 1622118:Lupro_RS01150
uniprot id: A0A0X8G4K5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1622118:Lupro RS11715
gene id: 1622118:Lupro_RS11715
uniprot id: A0A109RPE4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1622118:Lupro RS01935
gene id: 1622118:Lupro_RS01935
uniprot id: A0A0X8G4U1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1622118:Lupro RS05020
gene id: 1622118:Lupro_RS05020
uniprot id: A0A0X8G5V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1622118:Lupro RS03690
gene id: 1622118:Lupro_RS03690
uniprot id: A0A109RN31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1622118:Lupro RS07245
gene id: 1622118:Lupro_RS07245
uniprot id: A0A120IEA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1622118:Lupro RS06720
gene id: 1622118:Lupro_RS06720
uniprot id: A0A0X8G6J7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1622118:Lupro RS05650
gene id: 1622118:Lupro_RS05650
uniprot id: A0A109RNH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1622118:Lupro RS12055
gene id: 1622118:Lupro_RS12055
uniprot id: A0A120IEK2
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS03100
gene id: 1622118:Lupro_RS03100
uniprot id: A0A109RN60
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1622118:Lupro RS10560
gene id: 1622118:Lupro_RS10560
uniprot id: A0A0X8G7Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS01695
gene id: 1622118:Lupro_RS01695
uniprot id: A0A109RMT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1622118:Lupro RS05540
gene id: 1622118:Lupro_RS05540
uniprot id: A0A109RNE2
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS08580
gene id: 1622118:Lupro_RS08580
uniprot id: A0A0X8G753
names: Similarity
messages: Belongs to the UPF0145 family.

1622118:Lupro RS02015
gene id: 1622118:Lupro_RS02015
uniprot id: A0A0X8G4W5
names: Similarity
messages: Belongs to the AHA1 family.

1622118:Lupro RS05325
gene id: 1622118:Lupro_RS05325
uniprot id: A0A0X8G615
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS10315
gene id: 1622118:Lupro_RS10315
uniprot id: A0A0X8G7U0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1622118:Lupro RS07035
gene id: 1622118:Lupro_RS07035
uniprot id: A0A0X8G6I5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1622118:Lupro RS12420
gene id: 1622118:Lupro_RS12420
uniprot id: A0A109RPA0
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1622118:Lupro RS07590
gene id: 1622118:Lupro_RS07590
uniprot id: A0A0X8G6V2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS05665
gene id: 1622118:Lupro_RS05665
uniprot id: A0A109RNB9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1622118:Lupro RS03780
gene id: 1622118:Lupro_RS03780
uniprot id: A0A120IE34
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1622118:Lupro RS12050
gene id: 1622118:Lupro_RS12050
uniprot id: A0A120IEK4
names: Similarity
messages: Belongs to the AIR synthase family.

1622118:Lupro RS04165
gene id: 1622118:Lupro_RS04165
uniprot id: A0A0X8G5P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1622118:Lupro RS07395
gene id: 1622118:Lupro_RS07395
uniprot id: A0A0X8G6R1
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS05565
gene id: 1622118:Lupro_RS05565
uniprot id: A0A120IE70
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1622118:Lupro RS05035
gene id: 1622118:Lupro_RS05035
uniprot id: A0A0X8G5Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1622118:Lupro RS10970
gene id: 1622118:Lupro_RS10970
uniprot id: A0A109RP10
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1622118:Lupro RS09605
gene id: 1622118:Lupro_RS09605
uniprot id: A0A120IEF4
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1622118:Lupro RS10320
gene id: 1622118:Lupro_RS10320
uniprot id: A0A0X8G7V7
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS10645
gene id: 1622118:Lupro_RS10645
uniprot id: A0A109RNY5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1622118:Lupro RS02425
gene id: 1622118:Lupro_RS02425
uniprot id: A0A0X8G505
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1622118:Lupro RS04505
gene id: 1622118:Lupro_RS04505
uniprot id: A0A109RPF7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1622118:Lupro RS09625
gene id: 1622118:Lupro_RS09625
uniprot id: A0A0X8G7H8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS11395
gene id: 1622118:Lupro_RS11395
uniprot id: A0A109RP16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1622118:Lupro RS10730
gene id: 1622118:Lupro_RS10730
uniprot id: A0A0X8G8Q6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1622118:Lupro RS09815
gene id: 1622118:Lupro_RS09815
uniprot id: A0A0X8G7M9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1622118:Lupro RS04390
gene id: 1622118:Lupro_RS04390
uniprot id: A0A120IE47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS03935
gene id: 1622118:Lupro_RS03935
uniprot id: A0A109RP50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1622118:Lupro RS03715
gene id: 1622118:Lupro_RS03715
uniprot id: A0A0X8G5F2
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1622118:Lupro RS06405
gene id: 1622118:Lupro_RS06405
uniprot id: A0A0X8G6F7
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1622118:Lupro RS12230
gene id: 1622118:Lupro_RS12230
uniprot id: A0A109RPF9
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS07435
gene id: 1622118:Lupro_RS07435
uniprot id: A0A0X8G6N8
names: Similarity
messages: Belongs to the DtxR/MntR family.

1622118:Lupro RS10310
gene id: 1622118:Lupro_RS10310
uniprot id: A0A0X8G7T3
names: Similarity
messages: Belongs to the sigma-54 factor family.

1622118:Lupro RS00235
gene id: 1622118:Lupro_RS00235
uniprot id: A0A0X8G4A9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1622118:Lupro RS09970
gene id: 1622118:Lupro_RS09970
uniprot id: A0A0X8G7N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1622118:Lupro RS10280
gene id: 1622118:Lupro_RS10280
uniprot id: A0A0X8G7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1622118:Lupro RS01715
gene id: 1622118:Lupro_RS01715
uniprot id: A0A0X8G4S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1622118:Lupro RS11005
gene id: 1622118:Lupro_RS11005
uniprot id: A0A0X8G7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1622118:Lupro RS07405
gene id: 1622118:Lupro_RS07405
uniprot id: A0A120IEN2
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1622118:Lupro RS07625
gene id: 1622118:Lupro_RS07625
uniprot id: A0A0X8G6T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1622118:Lupro RS07260
gene id: 1622118:Lupro_RS07260
uniprot id: A0A0X8G6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS00390
gene id: 1622118:Lupro_RS00390
uniprot id: A0A0X8G495
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1622118:Lupro RS00540
gene id: 1622118:Lupro_RS00540
uniprot id: A0A0X8G4G5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1622118:Lupro RS01245
gene id: 1622118:Lupro_RS01245
uniprot id: A0A0X8G4L9
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1622118:Lupro RS09505
gene id: 1622118:Lupro_RS09505
uniprot id: A0A0X8G7K2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1622118:Lupro RS07605
gene id: 1622118:Lupro_RS07605
uniprot id: A0A0X8G6S3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1622118:Lupro RS00035
gene id: 1622118:Lupro_RS00035
uniprot id: A0A0X8G481
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS12220
gene id: 1622118:Lupro_RS12220
uniprot id: A0A0X8G8G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS10795
gene id: 1622118:Lupro_RS10795
uniprot id: A0A0X8G821
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1622118:Lupro RS10980
gene id: 1622118:Lupro_RS10980
uniprot id: A0A109RPY8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS00370
gene id: 1622118:Lupro_RS00370
uniprot id: A0A0X8G4A1
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS11345
gene id: 1622118:Lupro_RS11345
uniprot id: A0A0X8G831
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1622118:Lupro RS00430
gene id: 1622118:Lupro_RS00430
uniprot id: A0A109RMR2
names: Similarity
messages: Belongs to the CarB family.

1622118:Lupro RS09725
gene id: 1622118:Lupro_RS09725
uniprot id: A0A0X8G7M3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1622118:Lupro RS01570
gene id: 1622118:Lupro_RS01570
uniprot id: A0A0X8G4R9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1622118:Lupro RS00635
gene id: 1622118:Lupro_RS00635
uniprot id: A0A0X8G4E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1622118:Lupro RS07160
gene id: 1622118:Lupro_RS07160
uniprot id: A0A109RNI6
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1622118:Lupro RS12505
gene id: 1622118:Lupro_RS12505
uniprot id: A0A109RQE0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1622118:Lupro RS13070
gene id: 1622118:Lupro_RS13070
uniprot id: A0A120IEM6
names: Similarity
messages: Belongs to the IMPACT family.

1622118:Lupro RS08460
gene id: 1622118:Lupro_RS08460
uniprot id: A0A0X8G757
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1622118:Lupro RS08415
gene id: 1622118:Lupro_RS08415
uniprot id: A0A0X8G8Y5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS10060
gene id: 1622118:Lupro_RS10060
uniprot id: A0A0X8G7R9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1622118:Lupro RS09300
gene id: 1622118:Lupro_RS09300
uniprot id: A0A0X8G7D3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1622118:Lupro RS04955
gene id: 1622118:Lupro_RS04955
uniprot id: A0A0X8G5W3
names: Similarity
messages: Belongs to the citrate synthase family.

1622118:Lupro RS12840
gene id: 1622118:Lupro_RS12840
uniprot id: A0A120IEL9
names: Similarity
messages: Belongs to the ParB family.

1622118:Lupro RS04420
gene id: 1622118:Lupro_RS04420
uniprot id: A0A0X8G5Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1622118:Lupro RS05060
gene id: 1622118:Lupro_RS05060
uniprot id: A0A120IE61
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1622118:Lupro RS02465
gene id: 1622118:Lupro_RS02465
uniprot id: A0A109RMZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1622118:Lupro RS10900
gene id: 1622118:Lupro_RS10900
uniprot id: A0A109RP33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1622118:Lupro RS00870
gene id: 1622118:Lupro_RS00870
uniprot id: A0A109RMZ9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1622118:Lupro RS04585
gene id: 1622118:Lupro_RS04585
uniprot id: A0A0X8G5P4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1622118:Lupro RS01450
gene id: 1622118:Lupro_RS01450
uniprot id: A0A109RNV6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1622118:Lupro RS11200
gene id: 1622118:Lupro_RS11200
uniprot id: A0A109RPD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1622118:Lupro RS06320
gene id: 1622118:Lupro_RS06320
uniprot id: A0A0X8G6A9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1622118:Lupro RS03255
gene id: 1622118:Lupro_RS03255
uniprot id: A0A109RN50
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1622118:Lupro RS01510
gene id: 1622118:Lupro_RS01510
uniprot id: A0A109RMY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS01045
gene id: 1622118:Lupro_RS01045
uniprot id: A0A0X8G4J1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1622118:Lupro RS03745
gene id: 1622118:Lupro_RS03745
uniprot id: A0A0X8G5I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1622118:Lupro RS08165
gene id: 1622118:Lupro_RS08165
uniprot id: A0A0X8G705
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1622118:Lupro RS09075
gene id: 1622118:Lupro_RS09075
uniprot id: A0A0X8G7D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS10625
gene id: 1622118:Lupro_RS10625
uniprot id: A0A0X8G7Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS06960
gene id: 1622118:Lupro_RS06960
uniprot id: A0A0X8G6I9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1622118:Lupro RS05530
gene id: 1622118:Lupro_RS05530
uniprot id: A0A0X8G647
names: Similarity
messages: Belongs to the P(II) protein family.

1622118:Lupro RS03800
gene id: 1622118:Lupro_RS03800
uniprot id: A0A0X8G5I8
names: Similarity
messages: Belongs to the BshC family.

1622118:Lupro RS05265
gene id: 1622118:Lupro_RS05265
uniprot id: A0A0X8G604
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1622118:Lupro RS06515
gene id: 1622118:Lupro_RS06515
uniprot id: A0A120IE90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1622118:Lupro RS07505
gene id: 1622118:Lupro_RS07505
uniprot id: A0A120IEB1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1622118:Lupro RS01560
gene id: 1622118:Lupro_RS01560
uniprot id: A0A0X8G8T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1622118:Lupro RS08685
gene id: 1622118:Lupro_RS08685
uniprot id: A0A120IED5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1622118:Lupro RS01135
gene id: 1622118:Lupro_RS01135
uniprot id: A0A0X8G4J9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1622118:Lupro RS08775
gene id: 1622118:Lupro_RS08775
uniprot id: A0A0X8G790
names: Similarity
messages: Belongs to the GARS family.

1622118:Lupro RS04965
gene id: 1622118:Lupro_RS04965
uniprot id: A0A0X8G5V1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1622118:Lupro RS10375
gene id: 1622118:Lupro_RS10375
uniprot id: A0A0X8G7R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1622118:Lupro RS01095
gene id: 1622118:Lupro_RS01095
uniprot id: A0A0X8G4J8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1622118:Lupro RS10880
gene id: 1622118:Lupro_RS10880
uniprot id: A0A109RNZ6
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS06620
gene id: 1622118:Lupro_RS06620
uniprot id: A0A0X8G6H9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS10745
gene id: 1622118:Lupro_RS10745
uniprot id: A0A109RPX4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1622118:Lupro RS02155
gene id: 1622118:Lupro_RS02155
uniprot id: A0A0X8G4X4
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1622118:Lupro RS11210
gene id: 1622118:Lupro_RS11210
uniprot id: A0A109RP19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS03695
gene id: 1622118:Lupro_RS03695
uniprot id: A0A109RN39
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1622118:Lupro RS11845
gene id: 1622118:Lupro_RS11845
uniprot id: A0A0X8G891
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1622118:Lupro RS10930
gene id: 1622118:Lupro_RS10930
uniprot id: A0A0X8G7Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1622118:Lupro RS06500
gene id: 1622118:Lupro_RS06500
uniprot id: A0A0X8G6E6
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1622118:Lupro RS12005
gene id: 1622118:Lupro_RS12005
uniprot id: A0A0X8G8B3
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS08535
gene id: 1622118:Lupro_RS08535
uniprot id: A0A0X8G730
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1622118:Lupro RS10805
gene id: 1622118:Lupro_RS10805
uniprot id: A0A0X8G8R6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1622118:Lupro RS03970
gene id: 1622118:Lupro_RS03970
uniprot id: A0A0X8G5I3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1622118:Lupro RS06835
gene id: 1622118:Lupro_RS06835
uniprot id: A0A0X8G7A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1622118:Lupro RS11770
gene id: 1622118:Lupro_RS11770
uniprot id: A0A0X8G882
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1622118:Lupro RS08890
gene id: 1622118:Lupro_RS08890
uniprot id: A0A0X8G801
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS09705
gene id: 1622118:Lupro_RS09705
uniprot id: A0A0X8G8W2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1622118:Lupro RS05085
gene id: 1622118:Lupro_RS05085
uniprot id: A0A0X8G5Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1622118:Lupro RS11530
gene id: 1622118:Lupro_RS11530
uniprot id: A0A0X8G854
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1622118:Lupro RS00675
gene id: 1622118:Lupro_RS00675
uniprot id: A0A109RMS2
names: Similarity
messages: Belongs to the peptidase S51 family.

1622118:Lupro RS00865
gene id: 1622118:Lupro_RS00865
uniprot id: A0A120IDX5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1622118:Lupro RS10875
gene id: 1622118:Lupro_RS10875
uniprot id: A0A0X8G833
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1622118:Lupro RS00340
gene id: 1622118:Lupro_RS00340
uniprot id: A0A109RMT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1622118:Lupro RS07705
gene id: 1622118:Lupro_RS07705
uniprot id: A0A109RNM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1622118:Lupro RS10260
gene id: 1622118:Lupro_RS10260
uniprot id: A0A109RNY0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1622118:Lupro RS03540
gene id: 1622118:Lupro_RS03540
uniprot id: A0A120IE30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1622118:Lupro RS06170
gene id: 1622118:Lupro_RS06170
uniprot id: A0A0X8G686
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1622118:Lupro RS12700
gene id: 1622118:Lupro_RS12700
uniprot id: A0A0X8G8M2
names: Similarity
messages: Belongs to the RutC family.

1622118:Lupro RS06950
gene id: 1622118:Lupro_RS06950
uniprot id: A0A0X8G6K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1622118:Lupro RS10600
gene id: 1622118:Lupro_RS10600
uniprot id: A0A0X8G7Z3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1622118:Lupro RS01305
gene id: 1622118:Lupro_RS01305
uniprot id: A0A0X8G4N8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1622118:Lupro RS01865
gene id: 1622118:Lupro_RS01865
uniprot id: A0A0X8G5K1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1622118:Lupro RS08640
gene id: 1622118:Lupro_RS08640
uniprot id: A0A0X8G782
names: Similarity
messages: Belongs to the Skp family.

1622118:Lupro RS08665
gene id: 1622118:Lupro_RS08665
uniprot id: A0A0X8G7X2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1622118:Lupro RS08040
gene id: 1622118:Lupro_RS08040
uniprot id: A0A109RNL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1622118:Lupro RS03315
gene id: 1622118:Lupro_RS03315
uniprot id: A0A0X8G5A7
names: Similarity
messages: Belongs to the DEAD box helicase family.

1622118:Lupro RS10345
gene id: 1622118:Lupro_RS10345
uniprot id: A0A120IEG8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1622118:Lupro RS06220
gene id: 1622118:Lupro_RS06220
uniprot id: A0A109RPN5
names: Similarity
messages: Belongs to the CapA family.

1622118:Lupro RS03465
gene id: 1622118:Lupro_RS03465
uniprot id: A0A109RPD2
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS00410
gene id: 1622118:Lupro_RS00410
uniprot id: A0A0X8G4A0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS04120
gene id: 1622118:Lupro_RS04120
uniprot id: A0A0X8G5J5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1622118:Lupro RS10925
gene id: 1622118:Lupro_RS10925
uniprot id: A0A0X8G7Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1622118:Lupro RS12595
gene id: 1622118:Lupro_RS12595
uniprot id: A0A0X8G8P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1622118:Lupro RS11645
gene id: 1622118:Lupro_RS11645
uniprot id: A0A0X8G906
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1622118:Lupro RS08190
gene id: 1622118:Lupro_RS08190
uniprot id: A0A120IEC6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1622118:Lupro RS10735
gene id: 1622118:Lupro_RS10735
uniprot id: A0A109RP00
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS11090
gene id: 1622118:Lupro_RS11090
uniprot id: A0A0X8G804
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1622118:Lupro RS09315
gene id: 1622118:Lupro_RS09315
uniprot id: A0A0X8G7D5
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1622118:Lupro RS07640
gene id: 1622118:Lupro_RS07640
uniprot id: A0A109RNK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1622118:Lupro RS04445
gene id: 1622118:Lupro_RS04445
uniprot id: A0A0X8G5Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1622118:Lupro RS04680
gene id: 1622118:Lupro_RS04680
uniprot id: A0A0X8G5T2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS11610
gene id: 1622118:Lupro_RS11610
uniprot id: A0A0X8G864
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1622118:Lupro RS07535
gene id: 1622118:Lupro_RS07535
uniprot id: A0A0X8G6U4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1622118:Lupro RS03245
gene id: 1622118:Lupro_RS03245
uniprot id: A0A0X8G5C5
names: Similarity
messages: Belongs to the peptidase S13 family.

1622118:Lupro RS03775
gene id: 1622118:Lupro_RS03775
uniprot id: A0A120IE36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1622118:Lupro RS04295
gene id: 1622118:Lupro_RS04295
uniprot id: A0A0X8G6G2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1622118:Lupro RS10415
gene id: 1622118:Lupro_RS10415
uniprot id: A0A120IEH0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1622118:Lupro RS01205
gene id: 1622118:Lupro_RS01205
uniprot id: A0A109RP56
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS07495
gene id: 1622118:Lupro_RS07495
uniprot id: A0A120IEB0
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS10505
gene id: 1622118:Lupro_RS10505
uniprot id: A0A109RNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1622118:Lupro RS10885
gene id: 1622118:Lupro_RS10885
uniprot id: A0A0X8G8S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1622118:Lupro RS08675
gene id: 1622118:Lupro_RS08675
uniprot id: A0A120IED2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1622118:Lupro RS04605
gene id: 1622118:Lupro_RS04605
uniprot id: A0A0X8G5Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1622118:Lupro RS10150
gene id: 1622118:Lupro_RS10150
uniprot id: A0A0X8G7R5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1622118:Lupro RS04980
gene id: 1622118:Lupro_RS04980
uniprot id: A0A109RN86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1622118:Lupro RS10675
gene id: 1622118:Lupro_RS10675
uniprot id: A0A0X8G7V8
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1622118:Lupro RS01085
gene id: 1622118:Lupro_RS01085
uniprot id: A0A0X8G4K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1622118:Lupro RS13040
gene id: 1622118:Lupro_RS13040
uniprot id: A0A0X8G8Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1622118:Lupro RS07050
gene id: 1622118:Lupro_RS07050
uniprot id: A0A0X8G6N3
names: Similarity
messages: Belongs to the SCO1/2 family.

1622118:Lupro RS12490
gene id: 1622118:Lupro_RS12490
uniprot id: A0A109RP77
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1622118:Lupro RS09785
gene id: 1622118:Lupro_RS09785
uniprot id: A0A0X8G7N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1622118:Lupro RS08940
gene id: 1622118:Lupro_RS08940
uniprot id: A0A0X8G7E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1622118:Lupro RS07965
gene id: 1622118:Lupro_RS07965
uniprot id: A0A0X8G700
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS11035
gene id: 1622118:Lupro_RS11035
uniprot id: A0A0X8G829
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS03290
gene id: 1622118:Lupro_RS03290
uniprot id: A0A120IE26
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1622118:Lupro RS09445
gene id: 1622118:Lupro_RS09445
uniprot id: A0A109RNY4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1622118:Lupro RS09460
gene id: 1622118:Lupro_RS09460
uniprot id: A0A0X8G7F8
names: Similarity
messages: Belongs to the aspartokinase family.

1622118:Lupro RS12830
gene id: 1622118:Lupro_RS12830
uniprot id: A0A120IEM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1622118:Lupro RS12910
gene id: 1622118:Lupro_RS12910
uniprot id: A0A109RPC6
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS09295
gene id: 1622118:Lupro_RS09295
uniprot id: A0A109RQ16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1622118:Lupro RS08695
gene id: 1622118:Lupro_RS08695
uniprot id: A0A0X8G786
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1622118:Lupro RS05770
gene id: 1622118:Lupro_RS05770
uniprot id: A0A0X8G633
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1622118:Lupro RS08245
gene id: 1622118:Lupro_RS08245
uniprot id: A0A0X8G724
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1622118:Lupro RS05030
gene id: 1622118:Lupro_RS05030
uniprot id: A0A0X8G5X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1622118:Lupro RS07700
gene id: 1622118:Lupro_RS07700
uniprot id: A0A0X8G6U6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1622118:Lupro RS12440
gene id: 1622118:Lupro_RS12440
uniprot id: A0A0X8G8M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1622118:Lupro RS00320
gene id: 1622118:Lupro_RS00320
uniprot id: A0A0X8G4B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1622118:Lupro RS05485
gene id: 1622118:Lupro_RS05485
uniprot id: A0A109RPK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1622118:Lupro RS12100
gene id: 1622118:Lupro_RS12100
uniprot id: A0A0X8G8E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

1622118:Lupro RS06780
gene id: 1622118:Lupro_RS06780
uniprot id: A0A0X8G6K4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1622118:Lupro RS04305
gene id: 1622118:Lupro_RS04305
uniprot id: A0A120IE41
names: Similarity
messages: Belongs to the glutamate synthase family.

1622118:Lupro RS01210
gene id: 1622118:Lupro_RS01210
uniprot id: A0A0X8G4L3
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS10990
gene id: 1622118:Lupro_RS10990
uniprot id: A0A0X8G7Z8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1622118:Lupro RS06840
gene id: 1622118:Lupro_RS06840
uniprot id: A0A120IE96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1622118:Lupro RS04315
gene id: 1622118:Lupro_RS04315
uniprot id: A0A120IE45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1622118:Lupro RS02410
gene id: 1622118:Lupro_RS02410
uniprot id: A0A0X8G4Z7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1622118:Lupro RS11025
gene id: 1622118:Lupro_RS11025
uniprot id: A0A0X8G843
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1622118:Lupro RS06195
gene id: 1622118:Lupro_RS06195
uniprot id: A0A109RNS2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1622118:Lupro RS08770
gene id: 1622118:Lupro_RS08770
uniprot id: A0A0X8G7A3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1622118:Lupro RS09745
gene id: 1622118:Lupro_RS09745
uniprot id: A0A0X8G7N2
names: Similarity
messages: Belongs to the ArsC family.

1622118:Lupro RS10575
gene id: 1622118:Lupro_RS10575
uniprot id: A0A120IEH5
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1622118:Lupro RS02505
gene id: 1622118:Lupro_RS02505
uniprot id: A0A0X8G525
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1622118:Lupro RS07760
gene id: 1622118:Lupro_RS07760
uniprot id: A0A0X8G6X4
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS10640
gene id: 1622118:Lupro_RS10640
uniprot id: A0A0X8G7Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1622118:Lupro RS08840
gene id: 1622118:Lupro_RS08840
uniprot id: A0A0X8G772
names: Similarity
messages: Belongs to the DprA/Smf family.

1622118:Lupro RS03165
gene id: 1622118:Lupro_RS03165
uniprot id: A0A109RNF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1622118:Lupro RS11670
gene id: 1622118:Lupro_RS11670
uniprot id: A0A0X8G876
names: Similarity
messages: Belongs to the asparagine synthetase family.

1622118:Lupro RS01170
gene id: 1622118:Lupro_RS01170
uniprot id: A0A0X8G8Q2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1622118:Lupro RS12745
gene id: 1622118:Lupro_RS12745
uniprot id: A0A109RP75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS00145
gene id: 1622118:Lupro_RS00145
uniprot id: A0A0X8G465
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS12650
gene id: 1622118:Lupro_RS12650
uniprot id: A0A109RPB6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1622118:Lupro RS00175
gene id: 1622118:Lupro_RS00175
uniprot id: A0A109RMQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1622118:Lupro RS01535
gene id: 1622118:Lupro_RS01535
uniprot id: A0A120IDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1622118:Lupro RS06820
gene id: 1622118:Lupro_RS06820
uniprot id: A0A0X8G6K3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1622118:Lupro RS07955
gene id: 1622118:Lupro_RS07955
uniprot id: A0A120IEC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1622118:Lupro RS03760
gene id: 1622118:Lupro_RS03760
uniprot id: A0A0X8G6A4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

1622118:Lupro RS07065
gene id: 1622118:Lupro_RS07065
uniprot id: A0A109RNJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

1622118:Lupro RS08230
gene id: 1622118:Lupro_RS08230
uniprot id: A0A0X8G6Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1622118:Lupro RS10905
gene id: 1622118:Lupro_RS10905
uniprot id: A0A109RNZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1622118:Lupro RS01140
gene id: 1622118:Lupro_RS01140
uniprot id: A0A0X8G4M0
names: Similarity
messages: Belongs to the ArsC family.

1622118:Lupro RS04670
gene id: 1622118:Lupro_RS04670
uniprot id: A0A0X8G5Q1
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS08830
gene id: 1622118:Lupro_RS08830
uniprot id: A0A109RPN8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1622118:Lupro RS01915
gene id: 1622118:Lupro_RS01915
uniprot id: A0A0X8G4T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1622118:Lupro RS00155
gene id: 1622118:Lupro_RS00155
uniprot id: A0A0X8G470
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1622118:Lupro RS00425
gene id: 1622118:Lupro_RS00425
uniprot id: A0A109RMN5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1622118:Lupro RS10455
gene id: 1622118:Lupro_RS10455
uniprot id: A0A0X8G7S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1622118:Lupro RS07350
gene id: 1622118:Lupro_RS07350
uniprot id: A0A0X8G6N0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1622118:Lupro RS08370
gene id: 1622118:Lupro_RS08370
uniprot id: A0A0X8G709
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1622118:Lupro RS02495
gene id: 1622118:Lupro_RS02495
uniprot id: A0A0X8G4Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1622118:Lupro RS10955
gene id: 1622118:Lupro_RS10955
uniprot id: A0A0X8G844
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1622118:Lupro RS05110
gene id: 1622118:Lupro_RS05110
uniprot id: A0A0X8G5Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1622118:Lupro RS07075
gene id: 1622118:Lupro_RS07075
uniprot id: A0A120IEA0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1622118:Lupro RS12445
gene id: 1622118:Lupro_RS12445
uniprot id: A0A0X8G8G7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1622118:Lupro RS00455
gene id: 1622118:Lupro_RS00455
uniprot id: A0A0X8G4F3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS12960
gene id: 1622118:Lupro_RS12960
uniprot id: A0A0X8G8Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1622118:Lupro RS04275
gene id: 1622118:Lupro_RS04275
uniprot id: A0A0X8G5N9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Secreted

1622118:Lupro RS13035
gene id: 1622118:Lupro_RS13035
uniprot id: A0A120IEN9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1622118:Lupro RS00215
gene id: 1622118:Lupro_RS00215
uniprot id: A0A0X8G475
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1622118:Lupro RS08895
gene id: 1622118:Lupro_RS08895
uniprot id: A0A120IED8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS10390
gene id: 1622118:Lupro_RS10390
uniprot id: A0A0X8G7U1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1622118:Lupro RS02070
gene id: 1622118:Lupro_RS02070
uniprot id: A0A120IDZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

1622118:Lupro RS06155
gene id: 1622118:Lupro_RS06155
uniprot id: A0A0X8G6C0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1622118:Lupro RS01885
gene id: 1622118:Lupro_RS01885
uniprot id: A0A109RQ79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1622118:Lupro RS07735
gene id: 1622118:Lupro_RS07735
uniprot id: A0A0X8G6S9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1622118:Lupro RS07410
gene id: 1622118:Lupro_RS07410
uniprot id: A0A0X8G7G7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1622118:Lupro RS04405
gene id: 1622118:Lupro_RS04405
uniprot id: A0A109RN68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1622118:Lupro RS12140
gene id: 1622118:Lupro_RS12140
uniprot id: A0A0X8G8I2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1622118:Lupro RS00630
gene id: 1622118:Lupro_RS00630
uniprot id: A0A0X8G4C7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1622118:Lupro RS01490
gene id: 1622118:Lupro_RS01490
uniprot id: A0A0X8G4Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1622118:Lupro RS05550
gene id: 1622118:Lupro_RS05550
uniprot id: A0A120IE68
names: Similarity
messages: Belongs to the LOG family.

1622118:Lupro RS11740
gene id: 1622118:Lupro_RS11740
uniprot id: A0A109RQ20
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS03390
gene id: 1622118:Lupro_RS03390
uniprot id: A0A0X8G5E2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS11295
gene id: 1622118:Lupro_RS11295
uniprot id: A0A109RP35
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1622118:Lupro RS01010
gene id: 1622118:Lupro_RS01010
uniprot id: A0A0X8G4I1
names: Similarity
messages: Belongs to the YoeB family.

1622118:Lupro RS03995
gene id: 1622118:Lupro_RS03995
uniprot id: A0A109RP94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1622118:Lupro RS04640
gene id: 1622118:Lupro_RS04640
uniprot id: A0A109RN96
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1622118:Lupro RS06610
gene id: 1622118:Lupro_RS06610
uniprot id: A0A109RNF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1622118:Lupro RS10685
gene id: 1622118:Lupro_RS10685
uniprot id: A0A0X8G7W1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1622118:Lupro RS07285
gene id: 1622118:Lupro_RS07285
uniprot id: A0A0X8G6R8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1622118:Lupro RS05285
gene id: 1622118:Lupro_RS05285
uniprot id: A0A0X8G6T2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1622118:Lupro RS10030
gene id: 1622118:Lupro_RS10030
uniprot id: A0A109RQ47
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1622118:Lupro RS01650
gene id: 1622118:Lupro_RS01650
uniprot id: A0A0X8G4Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1622118:Lupro RS13000
gene id: 1622118:Lupro_RS13000
uniprot id: A0A109RQF5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1622118:Lupro RS12075
gene id: 1622118:Lupro_RS12075
uniprot id: A0A0X8G8C5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1622118:Lupro RS01500
gene id: 1622118:Lupro_RS01500
uniprot id: A0A0X8G4R2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1622118:Lupro RS08510
gene id: 1622118:Lupro_RS08510
uniprot id: A0A0X8G7V5
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1622118:Lupro RS00010
gene id: 1622118:Lupro_RS00010
uniprot id: A0A120IDW0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1622118:Lupro RS07980
gene id: 1622118:Lupro_RS07980
uniprot id: A0A0X8G6W9
names: Subcellular Location Annotation
messages: Membrane

1622118:Lupro RS12735
gene id: 1622118:Lupro_RS12735
uniprot id: A0A0X8G911
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1622118:Lupro RS07925
gene id: 1622118:Lupro_RS07925
uniprot id: A0A0X8G6X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1622118:Lupro RS10790
gene id: 1622118:Lupro_RS10790
uniprot id: A0A0X8G7Z9
names: Similarity
messages: Belongs to the EPSP synthase family.

1622118:Lupro RS05045
gene id: 1622118:Lupro_RS05045
uniprot id: A0A109RNC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1622118:Lupro RS03485
gene id: 1622118:Lupro_RS03485
uniprot id: A0A0X8G8U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1622118:Lupro RS05015
gene id: 1622118:Lupro_RS05015
uniprot id: A0A0X8G5U5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1622118:Lupro RS02640
gene id: 1622118:Lupro_RS02640
uniprot id: A0A0X8G527
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1622118:Lupro RS10290
gene id: 1622118:Lupro_RS10290
uniprot id: A0A0X8G7Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1622118:Lupro RS00150
gene id: 1622118:Lupro_RS00150
uniprot id: A0A0X8G497
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.