161895:CPHO RS04210
gene id: 161895:CPHO_RS04210
uniprot id: A0A1L7D224
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

161895:CPHO RS10705
gene id: 161895:CPHO_RS10705
uniprot id: A0A1L7D541
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

161895:CPHO RS01015
gene id: 161895:CPHO_RS01015
uniprot id: A0A1L7D0W7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

161895:CPHO RS04650
gene id: 161895:CPHO_RS04650
uniprot id: A0A1L7D2R8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

161895:CPHO RS04695
gene id: 161895:CPHO_RS04695
uniprot id: A0A1L7D2E9
names: Similarity
messages: Belongs to the acylphosphatase family.

161895:CPHO RS01815
gene id: 161895:CPHO_RS01815
uniprot id: A0A1L7D1J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS08885
gene id: 161895:CPHO_RS08885
uniprot id: A0A1L7D6I0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

161895:CPHO RS08925
gene id: 161895:CPHO_RS08925
uniprot id: A0A1L7D4X2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

161895:CPHO RS03620
gene id: 161895:CPHO_RS03620
uniprot id: A0A1L7D1T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

161895:CPHO RS05500
gene id: 161895:CPHO_RS05500
uniprot id: A0A1L7D2R0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

161895:CPHO RS06415
gene id: 161895:CPHO_RS06415
uniprot id: A0A1L7D371
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

161895:CPHO RS02795
gene id: 161895:CPHO_RS02795
uniprot id: A0A1L7D1K8
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS09960
gene id: 161895:CPHO_RS09960
uniprot id: A0A1L7D522
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

161895:CPHO RS01030
gene id: 161895:CPHO_RS01030
uniprot id: A0A1L7D193
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

161895:CPHO RS05845
gene id: 161895:CPHO_RS05845
uniprot id: A0A1L7D2V0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

161895:CPHO RS11750
gene id: 161895:CPHO_RS11750
uniprot id: A0A1L7D5L5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

161895:CPHO RS02210
gene id: 161895:CPHO_RS02210
uniprot id: A0A1L7D1R3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

161895:CPHO RS02375
gene id: 161895:CPHO_RS02375
uniprot id: A0A1L7D1G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS06720
gene id: 161895:CPHO_RS06720
uniprot id: A0A1L7D3D4
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

161895:CPHO RS03300
gene id: 161895:CPHO_RS03300
uniprot id: A0A1L7D1W6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

161895:CPHO RS07560
gene id: 161895:CPHO_RS07560
uniprot id: A0A1L7D3V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

161895:CPHO RS00850
gene id: 161895:CPHO_RS00850
uniprot id: A0A1L7D6F9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

161895:CPHO RS09765
gene id: 161895:CPHO_RS09765
uniprot id: A0A1L7D4X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS09000
gene id: 161895:CPHO_RS09000
uniprot id: A0A1L7D4B9
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS10100
gene id: 161895:CPHO_RS10100
uniprot id: A0A1L7D539
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

161895:CPHO RS06150
gene id: 161895:CPHO_RS06150
uniprot id: A0A1L7D6T3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

161895:CPHO RS00125
gene id: 161895:CPHO_RS00125
uniprot id: A0A1L7D0P1
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS05015
gene id: 161895:CPHO_RS05015
uniprot id: A0A1L7D2L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

161895:CPHO RS06200
gene id: 161895:CPHO_RS06200
uniprot id: A0A1L7D6B6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

161895:CPHO RS09945
gene id: 161895:CPHO_RS09945
uniprot id: A0A1L7D6K6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

161895:CPHO RS00815
gene id: 161895:CPHO_RS00815
uniprot id: A0A1L7D0Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS06160
gene id: 161895:CPHO_RS06160
uniprot id: A0A1L7D347
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

161895:CPHO RS11140
gene id: 161895:CPHO_RS11140
uniprot id: A0A1L7D5L2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS05025
gene id: 161895:CPHO_RS05025
uniprot id: A0A1L7D2Y5
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS08795
gene id: 161895:CPHO_RS08795
uniprot id: A0A1L7D4L2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

161895:CPHO RS05700
gene id: 161895:CPHO_RS05700
uniprot id: A0A1L7D2U2
names: Similarity
messages: Belongs to the peptidase A24 family.

161895:CPHO RS01430
gene id: 161895:CPHO_RS01430
uniprot id: A0A1L7D616
names: Similarity
messages: Belongs to the YjdM family.

161895:CPHO RS02070
gene id: 161895:CPHO_RS02070
uniprot id: A0A1L7D1A6
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

161895:CPHO RS02090
gene id: 161895:CPHO_RS02090
uniprot id: A0A1L7D164
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

161895:CPHO RS08135
gene id: 161895:CPHO_RS08135
uniprot id: A0A1L7D400
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

161895:CPHO RS04205
gene id: 161895:CPHO_RS04205
uniprot id: A0A1L7D231
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

161895:CPHO RS01785
gene id: 161895:CPHO_RS01785
uniprot id: A0A1L7D118
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS05540
gene id: 161895:CPHO_RS05540
uniprot id: A0A1L7D2Q1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

161895:CPHO RS10835
gene id: 161895:CPHO_RS10835
uniprot id: A0A1L7D5F9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

161895:CPHO RS03690
gene id: 161895:CPHO_RS03690
uniprot id: A0A1L7D236
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

161895:CPHO RS06510
gene id: 161895:CPHO_RS06510
uniprot id: A0A1L7D3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

161895:CPHO RS05160
gene id: 161895:CPHO_RS05160
uniprot id: A0A1L7D2M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS07865
gene id: 161895:CPHO_RS07865
uniprot id: A0A1L7D4D7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

161895:CPHO RS00580
gene id: 161895:CPHO_RS00580
uniprot id: A0A1L7D0N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

161895:CPHO RS12210
gene id: 161895:CPHO_RS12210
uniprot id: A0A1L7D5R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

161895:CPHO RS12385
gene id: 161895:CPHO_RS12385
uniprot id: A0A1L7D5X1
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

161895:CPHO RS05490
gene id: 161895:CPHO_RS05490
uniprot id: A0A1L7D2V7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS09165
gene id: 161895:CPHO_RS09165
uniprot id: A0A1L7D4C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

161895:CPHO RS01435
gene id: 161895:CPHO_RS01435
uniprot id: A0A1L7D647
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS10700
gene id: 161895:CPHO_RS10700
uniprot id: A0A1L7D5I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

161895:CPHO RS02325
gene id: 161895:CPHO_RS02325
uniprot id: A0A1L7D1I4
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

161895:CPHO RS07750
gene id: 161895:CPHO_RS07750
uniprot id: A0A1L7D6G6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

161895:CPHO RS05840
gene id: 161895:CPHO_RS05840
uniprot id: A0A1L7D2X4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS09935
gene id: 161895:CPHO_RS09935
uniprot id: A0A1L7D4Z8
names: Similarity
messages: Belongs to the PrpD family.

161895:CPHO RS00430
gene id: 161895:CPHO_RS00430
uniprot id: A0A1L7D110
names: Similarity
messages: Belongs to the UPF0145 family.

161895:CPHO RS11705
gene id: 161895:CPHO_RS11705
uniprot id: A0A1L7D5U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

161895:CPHO RS05635
gene id: 161895:CPHO_RS05635
uniprot id: A0A1L7D3C5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

161895:CPHO RS01420
gene id: 161895:CPHO_RS01420
uniprot id: A0A1L7D114
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

161895:CPHO RS02855
gene id: 161895:CPHO_RS02855
uniprot id: A0A1L7D1L8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

161895:CPHO RS06465
gene id: 161895:CPHO_RS06465
uniprot id: A0A1L7D329
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS03150
gene id: 161895:CPHO_RS03150
uniprot id: A0A1L7D1N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS11280
gene id: 161895:CPHO_RS11280
uniprot id: A0A1L7D5T4
names: Similarity
messages: Belongs to the isochorismate synthase family.

161895:CPHO RS10160
gene id: 161895:CPHO_RS10160
uniprot id: A0A1L7D552
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

161895:CPHO RS00425
gene id: 161895:CPHO_RS00425
uniprot id: A0A1L7D0M7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

161895:CPHO RS06360
gene id: 161895:CPHO_RS06360
uniprot id: A0A1L7D334
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

161895:CPHO RS04345
gene id: 161895:CPHO_RS04345
uniprot id: A0A1L7D271
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS05910
gene id: 161895:CPHO_RS05910
uniprot id: A0A1L7D3H5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

161895:CPHO RS10060
gene id: 161895:CPHO_RS10060
uniprot id: A0A1L7D4P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

161895:CPHO RS05920
gene id: 161895:CPHO_RS05920
uniprot id: A0A1L7D2Y1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

161895:CPHO RS12095
gene id: 161895:CPHO_RS12095
uniprot id: A0A1L7D5U8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

161895:CPHO RS02560
gene id: 161895:CPHO_RS02560
uniprot id: A0A1L7D1K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

161895:CPHO RS06265
gene id: 161895:CPHO_RS06265
uniprot id: A0A1L7D3F7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS06520
gene id: 161895:CPHO_RS06520
uniprot id: A0A1L7D3A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

161895:CPHO RS11040
gene id: 161895:CPHO_RS11040
uniprot id: A0A1L7D568
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS10375
gene id: 161895:CPHO_RS10375
uniprot id: A0A1L7D566
names: Similarity
messages: Belongs to the WXG100 family.

161895:CPHO RS11530
gene id: 161895:CPHO_RS11530
uniprot id: A0A1L7D5H3
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS07460
gene id: 161895:CPHO_RS07460
uniprot id: A0A1L7D3J1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

161895:CPHO RS09010
gene id: 161895:CPHO_RS09010
uniprot id: A0A1L7D484
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

161895:CPHO RS05010
gene id: 161895:CPHO_RS05010
uniprot id: A0A1L7D2H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

161895:CPHO RS04435
gene id: 161895:CPHO_RS04435
uniprot id: A0A1L7D266
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

161895:CPHO RS09270
gene id: 161895:CPHO_RS09270
uniprot id: A0A1L7D4V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

161895:CPHO RS10845
gene id: 161895:CPHO_RS10845
uniprot id: A0A1L7D5K7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

161895:CPHO RS04130
gene id: 161895:CPHO_RS04130
uniprot id: A0A1L7D2I5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

161895:CPHO RS11525
gene id: 161895:CPHO_RS11525
uniprot id: A0A1L7D5N8
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS05575
gene id: 161895:CPHO_RS05575
uniprot id: A0A1L7D2W9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

161895:CPHO RS12265
gene id: 161895:CPHO_RS12265
uniprot id: A0A1L7D5V3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

161895:CPHO RS00025
gene id: 161895:CPHO_RS00025
uniprot id: A0A1L7D0D7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

161895:CPHO RS06130
gene id: 161895:CPHO_RS06130
uniprot id: A0A1L7D341
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

161895:CPHO RS01820
gene id: 161895:CPHO_RS01820
uniprot id: A0A1L7D1C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS06950
gene id: 161895:CPHO_RS06950
uniprot id: A0A1L7D3G0
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

161895:CPHO RS05680
gene id: 161895:CPHO_RS05680
uniprot id: A0A1L7D2W6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

161895:CPHO RS08240
gene id: 161895:CPHO_RS08240
uniprot id: A0A1L7D410
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

161895:CPHO RS10710
gene id: 161895:CPHO_RS10710
uniprot id: A0A1L7D574
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

161895:CPHO RS05070
gene id: 161895:CPHO_RS05070
uniprot id: A0A1L7D2Y2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS10635
gene id: 161895:CPHO_RS10635
uniprot id: A0A1L7D5D4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

161895:CPHO RS06005
gene id: 161895:CPHO_RS06005
uniprot id: A0A1L7D2Y0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

161895:CPHO RS10950
gene id: 161895:CPHO_RS10950
uniprot id: A0A1L7D5M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS08180
gene id: 161895:CPHO_RS08180
uniprot id: A0A1L7D3X7
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS11045
gene id: 161895:CPHO_RS11045
uniprot id: A0A1L7D5G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

161895:CPHO RS10935
gene id: 161895:CPHO_RS10935
uniprot id: A0A1L7D5B5
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS01855
gene id: 161895:CPHO_RS01855
uniprot id: A0A1L7D169
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

161895:CPHO RS11695
gene id: 161895:CPHO_RS11695
uniprot id: A0A1L7D5K1
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

161895:CPHO RS01445
gene id: 161895:CPHO_RS01445
uniprot id: A0A1L7D149
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

161895:CPHO RS02415
gene id: 161895:CPHO_RS02415
uniprot id: A0A1L7D1A4
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS02220
gene id: 161895:CPHO_RS02220
uniprot id: A0A1L7D1G7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

161895:CPHO RS01010
gene id: 161895:CPHO_RS01010
uniprot id: A0A1L7D0V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

161895:CPHO RS03875
gene id: 161895:CPHO_RS03875
uniprot id: A0A1L7D1Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

161895:CPHO RS04860
gene id: 161895:CPHO_RS04860
uniprot id: A0A1L7D2K7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

161895:CPHO RS08820
gene id: 161895:CPHO_RS08820
uniprot id: A0A1L7D4B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

161895:CPHO RS01900
gene id: 161895:CPHO_RS01900
uniprot id: A0A1L7D1A9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

161895:CPHO RS03670
gene id: 161895:CPHO_RS03670
uniprot id: A0A1L7D6H8
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

161895:CPHO RS07605
gene id: 161895:CPHO_RS07605
uniprot id: A0A1L7D424
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

161895:CPHO RS10665
gene id: 161895:CPHO_RS10665
uniprot id: A0A1L7D5B1
names: Similarity
messages: Belongs to the asp23 family.

161895:CPHO RS04770
gene id: 161895:CPHO_RS04770
uniprot id: A0A1L7D2D2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

161895:CPHO RS04185
gene id: 161895:CPHO_RS04185
uniprot id: A0A1L7D2J5
names: Similarity
messages: Belongs to the asparagine synthetase family.

161895:CPHO RS10505
gene id: 161895:CPHO_RS10505
uniprot id: A0A1L7D511
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

161895:CPHO RS04855
gene id: 161895:CPHO_RS04855
uniprot id: A0A1L7D2V4
names: Similarity
messages: Belongs to the UPF0102 family.

161895:CPHO RS04195
gene id: 161895:CPHO_RS04195
uniprot id: A0A1L7D270
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

161895:CPHO RS03485
gene id: 161895:CPHO_RS03485
uniprot id: A0A1L7D1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

161895:CPHO RS11950
gene id: 161895:CPHO_RS11950
uniprot id: A0A1L7D692
names: Similarity
messages: Belongs to the thioredoxin family.

161895:CPHO RS11955
gene id: 161895:CPHO_RS11955
uniprot id: A0A1L7D646
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS03145
gene id: 161895:CPHO_RS03145
uniprot id: A0A1L7D6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

161895:CPHO RS08940
gene id: 161895:CPHO_RS08940
uniprot id: A0A1L7D4D2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

161895:CPHO RS04610
gene id: 161895:CPHO_RS04610
uniprot id: A0A1L7D2D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

161895:CPHO RS10280
gene id: 161895:CPHO_RS10280
uniprot id: A0A1L7D4Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

161895:CPHO RS07975
gene id: 161895:CPHO_RS07975
uniprot id: A0A1L7D3S1
names: Similarity
messages: Belongs to the LOG family.

161895:CPHO RS08930
gene id: 161895:CPHO_RS08930
uniprot id: A0A1L7D4P6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

161895:CPHO RS03580
gene id: 161895:CPHO_RS03580
uniprot id: A0A1L7D1V1
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS07410
gene id: 161895:CPHO_RS07410
uniprot id: A0A1L7D3K0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161895:CPHO RS06840
gene id: 161895:CPHO_RS06840
uniprot id: A0A1L7D3E0
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

161895:CPHO RS04935
gene id: 161895:CPHO_RS04935
uniprot id: A0A1L7D2E0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

161895:CPHO RS08035
gene id: 161895:CPHO_RS08035
uniprot id: A0A1L7D3X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

161895:CPHO RS06630
gene id: 161895:CPHO_RS06630
uniprot id: A0A1L7D3C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

161895:CPHO RS05145
gene id: 161895:CPHO_RS05145
uniprot id: A0A1L7D2P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

161895:CPHO RS05255
gene id: 161895:CPHO_RS05255
uniprot id: A0A1L7D376
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

161895:CPHO RS11110
gene id: 161895:CPHO_RS11110
uniprot id: A0A1L7D5D5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

161895:CPHO RS05535
gene id: 161895:CPHO_RS05535
uniprot id: A0A1L7D2S7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

161895:CPHO RS01870
gene id: 161895:CPHO_RS01870
uniprot id: A0A1L7D173
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

161895:CPHO RS08700
gene id: 161895:CPHO_RS08700
uniprot id: A0A1L7D4K0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

161895:CPHO RS07660
gene id: 161895:CPHO_RS07660
uniprot id: A0A1L7D431
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS09355
gene id: 161895:CPHO_RS09355
uniprot id: A0A1L7D4H3
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

161895:CPHO RS02600
gene id: 161895:CPHO_RS02600
uniprot id: A0A1L7D1R1
names: Similarity
messages: Belongs to the PstS family.

161895:CPHO RS05315
gene id: 161895:CPHO_RS05315
uniprot id: A0A1L7D2T8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

161895:CPHO RS04165
gene id: 161895:CPHO_RS04165
uniprot id: A0A1L7D239
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

161895:CPHO RS09830
gene id: 161895:CPHO_RS09830
uniprot id: A0A1L7D4Q3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161895:CPHO RS10840
gene id: 161895:CPHO_RS10840
uniprot id: A0A1L7D5S1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

161895:CPHO RS11745
gene id: 161895:CPHO_RS11745
uniprot id: A0A1L7D5T0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS11765
gene id: 161895:CPHO_RS11765
uniprot id: A0A1L7D5W0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

161895:CPHO RS08800
gene id: 161895:CPHO_RS08800
uniprot id: A0A1L7D4V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

161895:CPHO RS07380
gene id: 161895:CPHO_RS07380
uniprot id: A0A1L7D3L8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS00780
gene id: 161895:CPHO_RS00780
uniprot id: A0A1L7D0L7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

161895:CPHO RS04700
gene id: 161895:CPHO_RS04700
uniprot id: A0A1L7D2C7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

161895:CPHO RS04570
gene id: 161895:CPHO_RS04570
uniprot id: A0A1L7D282
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

161895:CPHO RS03005
gene id: 161895:CPHO_RS03005
uniprot id: A0A1L7D230
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS05895
gene id: 161895:CPHO_RS05895
uniprot id: A0A1L7D2W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

161895:CPHO RS00865
gene id: 161895:CPHO_RS00865
uniprot id: A0A1L7D0N3
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS06045
gene id: 161895:CPHO_RS06045
uniprot id: A0A1L7D2W5
names: Similarity
messages: Belongs to the UPF0237 family.

161895:CPHO RS06165
gene id: 161895:CPHO_RS06165
uniprot id: A0A1L7D2Y6
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

161895:CPHO RS08015
gene id: 161895:CPHO_RS08015
uniprot id: A0A1L7D3W1
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

161895:CPHO RS09285
gene id: 161895:CPHO_RS09285
uniprot id: A0A1L7D4C1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

161895:CPHO RS05660
gene id: 161895:CPHO_RS05660
uniprot id: A0A1L7D2Z0
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS07655
gene id: 161895:CPHO_RS07655
uniprot id: A0A1L7D3T5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

161895:CPHO RS10615
gene id: 161895:CPHO_RS10615
uniprot id: A0A1L7D5A4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

161895:CPHO RS03540
gene id: 161895:CPHO_RS03540
uniprot id: A0A1L7D1Z9
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS10005
gene id: 161895:CPHO_RS10005
uniprot id: A0A1L7D508
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

161895:CPHO RS04410
gene id: 161895:CPHO_RS04410
uniprot id: A0A1L7D2M9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

161895:CPHO RS05835
gene id: 161895:CPHO_RS05835
uniprot id: A0A1L7D317
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS08685
gene id: 161895:CPHO_RS08685
uniprot id: A0A1L7D4J3
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

161895:CPHO RS12335
gene id: 161895:CPHO_RS12335
uniprot id: A0A1L7D5S6
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

161895:CPHO RS05665
gene id: 161895:CPHO_RS05665
uniprot id: A0A1L7D2U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

161895:CPHO RS02300
gene id: 161895:CPHO_RS02300
uniprot id: A0A1L7D1E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS02105
gene id: 161895:CPHO_RS02105
uniprot id: A0A1L7D1I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

161895:CPHO RS01060
gene id: 161895:CPHO_RS01060
uniprot id: A0A1L7D0R2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS03510
gene id: 161895:CPHO_RS03510
uniprot id: A0A1L7D1W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161895:CPHO RS10490
gene id: 161895:CPHO_RS10490
uniprot id: A0A1L7D526
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

161895:CPHO RS09705
gene id: 161895:CPHO_RS09705
uniprot id: A0A1L7D4V6
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

161895:CPHO RS01655
gene id: 161895:CPHO_RS01655
uniprot id: A0A1L7D6A0
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

161895:CPHO RS11550
gene id: 161895:CPHO_RS11550
uniprot id: A0A1L7D630
names: Similarity
messages: Belongs to the AccD/PCCB family.

161895:CPHO RS04160
gene id: 161895:CPHO_RS04160
uniprot id: A0A1L7D259
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

161895:CPHO RS05955
gene id: 161895:CPHO_RS05955
uniprot id: A0A1L7D3A9
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

161895:CPHO RS04825
gene id: 161895:CPHO_RS04825
uniprot id: A0A1L7D2K9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS04465
gene id: 161895:CPHO_RS04465
uniprot id: A0A1L7D2N8
names: Similarity
messages: Belongs to the asparaginase 1 family.

161895:CPHO RS12195
gene id: 161895:CPHO_RS12195
uniprot id: A0A1L7D687
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS04865
gene id: 161895:CPHO_RS04865
uniprot id: A0A1L7D2G8
names: Similarity
messages: Belongs to the DprA/Smf family.

161895:CPHO RS11000
gene id: 161895:CPHO_RS11000
uniprot id: A0A1L7D589
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS04010
gene id: 161895:CPHO_RS04010
uniprot id: A0A1L7D2B8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

161895:CPHO RS05065
gene id: 161895:CPHO_RS05065
uniprot id: A0A1L7D2M6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

161895:CPHO RS10550
gene id: 161895:CPHO_RS10550
uniprot id: A0A1L7D591
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161895:CPHO RS05155
gene id: 161895:CPHO_RS05155
uniprot id: A0A1L7D2R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS12185
gene id: 161895:CPHO_RS12185
uniprot id: A0A1L7D638
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

161895:CPHO RS04880
gene id: 161895:CPHO_RS04880
uniprot id: A0A1L7D2L9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

161895:CPHO RS10890
gene id: 161895:CPHO_RS10890
uniprot id: A0A1L7D5G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

161895:CPHO RS06410
gene id: 161895:CPHO_RS06410
uniprot id: A0A1L7D3B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

161895:CPHO RS04015
gene id: 161895:CPHO_RS04015
uniprot id: A0A1L7D275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

161895:CPHO RS05850
gene id: 161895:CPHO_RS05850
uniprot id: A0A1L7D2Z4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

161895:CPHO RS12410
gene id: 161895:CPHO_RS12410
uniprot id: A0A1L7D5W6
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS05150
gene id: 161895:CPHO_RS05150
uniprot id: A0A1L7D2H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

161895:CPHO RS03295
gene id: 161895:CPHO_RS03295
uniprot id: A0A1L7D208
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

161895:CPHO RS09605
gene id: 161895:CPHO_RS09605
uniprot id: A0A1L7D4J1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161895:CPHO RS09295
gene id: 161895:CPHO_RS09295
uniprot id: A0A1L7D4N4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS01315
gene id: 161895:CPHO_RS01315
uniprot id: A0A1L7D101
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

161895:CPHO RS10625
gene id: 161895:CPHO_RS10625
uniprot id: A0A1L7D534
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

161895:CPHO RS00010
gene id: 161895:CPHO_RS00010
uniprot id: A0A1L7D0B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

161895:CPHO RS07055
gene id: 161895:CPHO_RS07055
uniprot id: A0A1L7D3M3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

161895:CPHO RS08705
gene id: 161895:CPHO_RS08705
uniprot id: A0A1L7D471
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

161895:CPHO RS09880
gene id: 161895:CPHO_RS09880
uniprot id: A0A1L7D4Y9
names: Similarity
messages: Belongs to the AccD/PCCB family.

161895:CPHO RS02925
gene id: 161895:CPHO_RS02925
uniprot id: A0A1L7D1K0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

161895:CPHO RS11960
gene id: 161895:CPHO_RS11960
uniprot id: A0A1L7D5P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

161895:CPHO RS11155
gene id: 161895:CPHO_RS11155
uniprot id: A0A1L7D5A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

161895:CPHO RS02160
gene id: 161895:CPHO_RS02160
uniprot id: A0A1L7D1J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

161895:CPHO RS03095
gene id: 161895:CPHO_RS03095
uniprot id: A0A1L7D1T5
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

161895:CPHO RS10855
gene id: 161895:CPHO_RS10855
uniprot id: A0A1L7D595
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

161895:CPHO RS07830
gene id: 161895:CPHO_RS07830
uniprot id: A0A1L7D3Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

161895:CPHO RS01810
gene id: 161895:CPHO_RS01810
uniprot id: A0A1L7D162
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

161895:CPHO RS00820
gene id: 161895:CPHO_RS00820
uniprot id: A0A1L7D0W1
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS09430
gene id: 161895:CPHO_RS09430
uniprot id: A0A1L7D4G2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

161895:CPHO RS12280
gene id: 161895:CPHO_RS12280
uniprot id: A0A1L7D5R7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161895:CPHO RS05915
gene id: 161895:CPHO_RS05915
uniprot id: A0A1L7D321
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

161895:CPHO RS10030
gene id: 161895:CPHO_RS10030
uniprot id: A0A1L7D532
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

161895:CPHO RS07505
gene id: 161895:CPHO_RS07505
uniprot id: A0A1L7D3N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS04785
gene id: 161895:CPHO_RS04785
uniprot id: A0A1L7D6C7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

161895:CPHO RS05925
gene id: 161895:CPHO_RS05925
uniprot id: A0A1L7D313
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

161895:CPHO RS04995
gene id: 161895:CPHO_RS04995
uniprot id: A0A1L7D2N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

161895:CPHO RS03240
gene id: 161895:CPHO_RS03240
uniprot id: A0A1L7D1V5
names: Similarity
messages: Belongs to the peptidase M1 family.

161895:CPHO RS07060
gene id: 161895:CPHO_RS07060
uniprot id: A0A1L7D3H1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

161895:CPHO RS10650
gene id: 161895:CPHO_RS10650
uniprot id: A0A1L7D527
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

161895:CPHO RS09685
gene id: 161895:CPHO_RS09685
uniprot id: A0A1L7D4M2
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

161895:CPHO RS07640
gene id: 161895:CPHO_RS07640
uniprot id: A0A1L7D3X0
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS11830
gene id: 161895:CPHO_RS11830
uniprot id: A0A1L7D6N2
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS02095
gene id: 161895:CPHO_RS02095
uniprot id: A0A1L7D1A8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

161895:CPHO RS03160
gene id: 161895:CPHO_RS03160
uniprot id: A0A1L7D251
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS01505
gene id: 161895:CPHO_RS01505
uniprot id: A0A1L7D187
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

161895:CPHO RS10995
gene id: 161895:CPHO_RS10995
uniprot id: A0A1L7D594
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

161895:CPHO RS03470
gene id: 161895:CPHO_RS03470
uniprot id: A0A1L7D299
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

161895:CPHO RS10910
gene id: 161895:CPHO_RS10910
uniprot id: A0A1L7D5A5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

161895:CPHO RS00590
gene id: 161895:CPHO_RS00590
uniprot id: A0A1L7D5Z7
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

161895:CPHO RS07480
gene id: 161895:CPHO_RS07480
uniprot id: A0A1L7D3Q5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

161895:CPHO RS05730
gene id: 161895:CPHO_RS05730
uniprot id: A0A1L7D2X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

161895:CPHO RS02410
gene id: 161895:CPHO_RS02410
uniprot id: A0A1L7D1B8
names: Similarity
messages: Belongs to the TPP enzyme family.

161895:CPHO RS10485
gene id: 161895:CPHO_RS10485
uniprot id: A0A1L7D4Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

161895:CPHO RS04335
gene id: 161895:CPHO_RS04335
uniprot id: A0A1L7D2D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

161895:CPHO RS10510
gene id: 161895:CPHO_RS10510
uniprot id: A0A1L7D514
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS03330
gene id: 161895:CPHO_RS03330
uniprot id: A0A1L7D1W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

161895:CPHO RS04255
gene id: 161895:CPHO_RS04255
uniprot id: A0A1L7D2B1
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

161895:CPHO RS10915
gene id: 161895:CPHO_RS10915
uniprot id: A0A1L7D551
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS07430
gene id: 161895:CPHO_RS07430
uniprot id: A0A1L7D3Z1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

161895:CPHO RS04485
gene id: 161895:CPHO_RS04485
uniprot id: A0A1L7D6B8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

161895:CPHO RS09025
gene id: 161895:CPHO_RS09025
uniprot id: A0A1L7D4C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

161895:CPHO RS04590
gene id: 161895:CPHO_RS04590
uniprot id: A0A1L7D2F5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

161895:CPHO RS07990
gene id: 161895:CPHO_RS07990
uniprot id: A0A1L7D3U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

161895:CPHO RS04025
gene id: 161895:CPHO_RS04025
uniprot id: A0A1L7D204
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

161895:CPHO RS02810
gene id: 161895:CPHO_RS02810
uniprot id: A0A1L7D1M4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

161895:CPHO RS11170
gene id: 161895:CPHO_RS11170
uniprot id: A0A1L7D5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161895:CPHO RS10430
gene id: 161895:CPHO_RS10430
uniprot id: A0A1L7D516
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

161895:CPHO RS06390
gene id: 161895:CPHO_RS06390
uniprot id: A0A1L7D361
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

161895:CPHO RS11005
gene id: 161895:CPHO_RS11005
uniprot id: A0A1L7D5C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

161895:CPHO RS04375
gene id: 161895:CPHO_RS04375
uniprot id: A0A1L7D2A6
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.

161895:CPHO RS06705
gene id: 161895:CPHO_RS06705
uniprot id: A0A1L7D3G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

161895:CPHO RS05790
gene id: 161895:CPHO_RS05790
uniprot id: A0A1L7D2U0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

161895:CPHO RS06125
gene id: 161895:CPHO_RS06125
uniprot id: A0A1L7D2Z8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

161895:CPHO RS01275
gene id: 161895:CPHO_RS01275
uniprot id: A0A1L7D102
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

161895:CPHO RS07360
gene id: 161895:CPHO_RS07360
uniprot id: A0A1L7D3Y3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS10965
gene id: 161895:CPHO_RS10965
uniprot id: A0A1L7D6R3
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

161895:CPHO RS07620
gene id: 161895:CPHO_RS07620
uniprot id: A0A1L7D3Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

161895:CPHO RS03820
gene id: 161895:CPHO_RS03820
uniprot id: A0A1L7D288
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

161895:CPHO RS04350
gene id: 161895:CPHO_RS04350
uniprot id: A0A1L7D2B4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS10420
gene id: 161895:CPHO_RS10420
uniprot id: A0A1L7D5D8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

161895:CPHO RS05795
gene id: 161895:CPHO_RS05795
uniprot id: A0A1L7D2Y3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

161895:CPHO RS08970
gene id: 161895:CPHO_RS08970
uniprot id: A0A1L7D497
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

161895:CPHO RS05265
gene id: 161895:CPHO_RS05265
uniprot id: A0A1L7D2N0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

161895:CPHO RS04125
gene id: 161895:CPHO_RS04125
uniprot id: A0A1L7D2I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS11205
gene id: 161895:CPHO_RS11205
uniprot id: A0A1L7D5X5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161895:CPHO RS06790
gene id: 161895:CPHO_RS06790
uniprot id: A0A1L7D3P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

161895:CPHO RS01945
gene id: 161895:CPHO_RS01945
uniprot id: A0A1L7D187
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

161895:CPHO RS05095
gene id: 161895:CPHO_RS05095
uniprot id: A0A1L7D2N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

161895:CPHO RS10495
gene id: 161895:CPHO_RS10495
uniprot id: A0A1L7D4X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

161895:CPHO RS12085
gene id: 161895:CPHO_RS12085
uniprot id: A0A1L7D665
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS06460
gene id: 161895:CPHO_RS06460
uniprot id: A0A1L7D397
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

161895:CPHO RS12200
gene id: 161895:CPHO_RS12200
uniprot id: A0A1L7D5U0
names: Function
names: Similarity
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

161895:CPHO RS04515
gene id: 161895:CPHO_RS04515
uniprot id: A0A1L7D6J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

161895:CPHO RS09940
gene id: 161895:CPHO_RS09940
uniprot id: A0A1L7D4R6
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

161895:CPHO RS03555
gene id: 161895:CPHO_RS03555
uniprot id: A0A1L7D662
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

161895:CPHO RS11470
gene id: 161895:CPHO_RS11470
uniprot id: A0A1L7D5D1
names: Similarity
messages: Belongs to the universal stress protein A family.

161895:CPHO RS07850
gene id: 161895:CPHO_RS07850
uniprot id: A0A1L7D3W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

161895:CPHO RS01175
gene id: 161895:CPHO_RS01175
uniprot id: A0A1L7D0Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS05045
gene id: 161895:CPHO_RS05045
uniprot id: A0A1L7D2F7
names: Similarity
messages: Belongs to the ribF family.

161895:CPHO RS10270
gene id: 161895:CPHO_RS10270
uniprot id: A0A1L7D4W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

161895:CPHO RS08140
gene id: 161895:CPHO_RS08140
uniprot id: A0A1L7D498
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

161895:CPHO RS10640
gene id: 161895:CPHO_RS10640
uniprot id: A0A1L7D5P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

161895:CPHO RS07575
gene id: 161895:CPHO_RS07575
uniprot id: A0A1L7D3L2
names: Similarity
messages: Belongs to the UPF0045 family.

161895:CPHO RS06765
gene id: 161895:CPHO_RS06765
uniprot id: A0A1L7D6I6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

161895:CPHO RS12500
gene id: 161895:CPHO_RS12500
uniprot id: A0A1L7D685
names: Similarity
messages: Belongs to the peptidase M1 family.

161895:CPHO RS01075
gene id: 161895:CPHO_RS01075
uniprot id: A0A1L7D1A1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161895:CPHO RS10455
gene id: 161895:CPHO_RS10455
uniprot id: A0A1L7D506
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

161895:CPHO RS10660
gene id: 161895:CPHO_RS10660
uniprot id: A0A1L7D507
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

161895:CPHO RS05570
gene id: 161895:CPHO_RS05570
uniprot id: A0A1L7D3B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

161895:CPHO RS01715
gene id: 161895:CPHO_RS01715
uniprot id: A0A1L7D150
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

161895:CPHO RS10355
gene id: 161895:CPHO_RS10355
uniprot id: A0A1L7D5C8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

161895:CPHO RS10865
gene id: 161895:CPHO_RS10865
uniprot id: A0A1L7D5D7
names: Similarity
messages: Belongs to the peptidase S13 family.

161895:CPHO RS10870
gene id: 161895:CPHO_RS10870
uniprot id: A0A1L7D6N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

161895:CPHO RS08880
gene id: 161895:CPHO_RS08880
uniprot id: A0A1L7D4C2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

161895:CPHO RS11805
gene id: 161895:CPHO_RS11805
uniprot id: A0A1L7D5M3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

161895:CPHO RS05720
gene id: 161895:CPHO_RS05720
uniprot id: A0A1L7D2V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

161895:CPHO RS06730
gene id: 161895:CPHO_RS06730
uniprot id: A0A1L7D3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

161895:CPHO RS04830
gene id: 161895:CPHO_RS04830
uniprot id: A0A1L7D2G4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

161895:CPHO RS09840
gene id: 161895:CPHO_RS09840
uniprot id: A0A1L7D505
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

161895:CPHO RS07535
gene id: 161895:CPHO_RS07535
uniprot id: A0A1L7D3P9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

161895:CPHO RS12480
gene id: 161895:CPHO_RS12480
uniprot id: A0A1L7D5X6
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS05825
gene id: 161895:CPHO_RS05825
uniprot id: A0A1L7D2Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

161895:CPHO RS06145
gene id: 161895:CPHO_RS06145
uniprot id: A0A1L7D358
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

161895:CPHO RS03550
gene id: 161895:CPHO_RS03550
uniprot id: A0A1L7D1X4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

161895:CPHO RS11735
gene id: 161895:CPHO_RS11735
uniprot id: A0A1L7D5I2
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

161895:CPHO RS00870
gene id: 161895:CPHO_RS00870
uniprot id: A0A1L7D0U6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS07400
gene id: 161895:CPHO_RS07400
uniprot id: A0A1L7D3S8
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS09420
gene id: 161895:CPHO_RS09420
uniprot id: A0A1L7D4R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

161895:CPHO RS03000
gene id: 161895:CPHO_RS03000
uniprot id: A0A1L7D1Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

161895:CPHO RS02545
gene id: 161895:CPHO_RS02545
uniprot id: A0A1L7D1I0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

161895:CPHO RS10945
gene id: 161895:CPHO_RS10945
uniprot id: A0A1L7D5T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS10035
gene id: 161895:CPHO_RS10035
uniprot id: A0A1L7D5E1
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS04965
gene id: 161895:CPHO_RS04965
uniprot id: A0A1L7D2W2
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

161895:CPHO RS03940
gene id: 161895:CPHO_RS03940
uniprot id: A0A1L7D206
names: Similarity
messages: Belongs to the glutamine synthetase family.

161895:CPHO RS01240
gene id: 161895:CPHO_RS01240
uniprot id: A0A1L7D0T8
names: Subcellular Location Annotation
messages: Cytoplasm

161895:CPHO RS11235
gene id: 161895:CPHO_RS11235
uniprot id: A0A1L7D5J8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

161895:CPHO RS10850
gene id: 161895:CPHO_RS10850
uniprot id: A0A1L7D561
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

161895:CPHO RS11510
gene id: 161895:CPHO_RS11510
uniprot id: A0A1L7D5G5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

161895:CPHO RS12380
gene id: 161895:CPHO_RS12380
uniprot id: A0A1L7D6B9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

161895:CPHO RS04520
gene id: 161895:CPHO_RS04520
uniprot id: A0A1L7D2A0
names: Similarity
messages: Belongs to the IMPACT family.

161895:CPHO RS12000
gene id: 161895:CPHO_RS12000
uniprot id: A0A1L7D602
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

161895:CPHO RS07600
gene id: 161895:CPHO_RS07600
uniprot id: A0A1L7D3S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

161895:CPHO RS10435
gene id: 161895:CPHO_RS10435
uniprot id: A0A1L7D4W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

161895:CPHO RS09595
gene id: 161895:CPHO_RS09595
uniprot id: A0A1L7D4T8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

161895:CPHO RS08720
gene id: 161895:CPHO_RS08720
uniprot id: A0A1L7D4E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

161895:CPHO RS02860
gene id: 161895:CPHO_RS02860
uniprot id: A0A1L7D1J0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

161895:CPHO RS10515
gene id: 161895:CPHO_RS10515
uniprot id: A0A1L7D537
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

161895:CPHO RS02170
gene id: 161895:CPHO_RS02170
uniprot id: A0A1L7D1C2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

161895:CPHO RS04840
gene id: 161895:CPHO_RS04840
uniprot id: A0A1L7D2E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

161895:CPHO RS05865
gene id: 161895:CPHO_RS05865
uniprot id: A0A1L7D314
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

161895:CPHO RS02230
gene id: 161895:CPHO_RS02230
uniprot id: A0A1L7D1D2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

161895:CPHO RS05120
gene id: 161895:CPHO_RS05120
uniprot id: A0A1L7D2N6
names: Similarity
messages: Belongs to the PspA/IM30 family.

161895:CPHO RS03885
gene id: 161895:CPHO_RS03885
uniprot id: A0A1L7D674
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

161895:CPHO RS04325
gene id: 161895:CPHO_RS04325
uniprot id: A0A1L7D253
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS08320
gene id: 161895:CPHO_RS08320
uniprot id: A0A1L7D6K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

161895:CPHO RS12080
gene id: 161895:CPHO_RS12080
uniprot id: A0A1L7D6B2
names: Similarity
messages: Belongs to the FPG family.

161895:CPHO RS12405
gene id: 161895:CPHO_RS12405
uniprot id: A0A1L7D5W7
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS03610
gene id: 161895:CPHO_RS03610
uniprot id: A0A1L7D1Y2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

161895:CPHO RS10440
gene id: 161895:CPHO_RS10440
uniprot id: A0A1L7D573
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

161895:CPHO RS10645
gene id: 161895:CPHO_RS10645
uniprot id: A0A1L7D5H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

161895:CPHO RS05050
gene id: 161895:CPHO_RS05050
uniprot id: A0A1L7D2P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

161895:CPHO RS02530
gene id: 161895:CPHO_RS02530
uniprot id: A0A1L7D1Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

161895:CPHO RS08895
gene id: 161895:CPHO_RS08895
uniprot id: A0A1L7D4H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

161895:CPHO RS10305
gene id: 161895:CPHO_RS10305
uniprot id: A0A1L7D4W9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

161895:CPHO RS08160
gene id: 161895:CPHO_RS08160
uniprot id: A0A1L7D411
names: Similarity
messages: Belongs to the FBPase class 2 family.

161895:CPHO RS06540
gene id: 161895:CPHO_RS06540
uniprot id: A0A1L7D363
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

161895:CPHO RS05200
gene id: 161895:CPHO_RS05200
uniprot id: A0A1L7D365
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

161895:CPHO RS10170
gene id: 161895:CPHO_RS10170
uniprot id: A0A1L7D597
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161895:CPHO RS05885
gene id: 161895:CPHO_RS05885
uniprot id: A0A1L7D326
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

161895:CPHO RS03215
gene id: 161895:CPHO_RS03215
uniprot id: A0A1L7D1S0
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

161895:CPHO RS05000
gene id: 161895:CPHO_RS05000
uniprot id: A0A1L7D2J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

161895:CPHO RS02390
gene id: 161895:CPHO_RS02390
uniprot id: A0A1L7D1J4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

161895:CPHO RS10095
gene id: 161895:CPHO_RS10095
uniprot id: A0A1L7D4W2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

161895:CPHO RS01860
gene id: 161895:CPHO_RS01860
uniprot id: A0A1L7D123
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS05905
gene id: 161895:CPHO_RS05905
uniprot id: A0A1L7D3A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

161895:CPHO RS06565
gene id: 161895:CPHO_RS06565
uniprot id: A0A1L7D392
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

161895:CPHO RS01745
gene id: 161895:CPHO_RS01745
uniprot id: A0A1L7D148
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

161895:CPHO RS04890
gene id: 161895:CPHO_RS04890
uniprot id: A0A1L7D2F0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS05560
gene id: 161895:CPHO_RS05560
uniprot id: A0A1L7D346
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS10525
gene id: 161895:CPHO_RS10525
uniprot id: A0A1L7D5M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

161895:CPHO RS02920
gene id: 161895:CPHO_RS02920
uniprot id: A0A1L7D1M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

161895:CPHO RS11330
gene id: 161895:CPHO_RS11330
uniprot id: A0A1L7D734
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

161895:CPHO RS10960
gene id: 161895:CPHO_RS10960
uniprot id: A0A1L7D5B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

161895:CPHO RS08065
gene id: 161895:CPHO_RS08065
uniprot id: A0A1L7D6H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

161895:CPHO RS01830
gene id: 161895:CPHO_RS01830
uniprot id: A0A1L7D170
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

161895:CPHO RS05075
gene id: 161895:CPHO_RS05075
uniprot id: A0A1L7D344
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

161895:CPHO RS00275
gene id: 161895:CPHO_RS00275
uniprot id: A0A1L7D0E2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

161895:CPHO RS05290
gene id: 161895:CPHO_RS05290
uniprot id: A0A1L7D2M2
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

161895:CPHO RS10255
gene id: 161895:CPHO_RS10255
uniprot id: A0A1L7D4T2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161895:CPHO RS10765
gene id: 161895:CPHO_RS10765
uniprot id: A0A1L7D5R3
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS06570
gene id: 161895:CPHO_RS06570
uniprot id: A0A1L7D3B7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

161895:CPHO RS02065
gene id: 161895:CPHO_RS02065
uniprot id: A0A1L7D1C4
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS12145
gene id: 161895:CPHO_RS12145
uniprot id: A0A1L7D5S7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS04580
gene id: 161895:CPHO_RS04580
uniprot id: A0A1L7D2D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

161895:CPHO RS04885
gene id: 161895:CPHO_RS04885
uniprot id: A0A1L7D2H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

161895:CPHO RS02155
gene id: 161895:CPHO_RS02155
uniprot id: A0A1L7D1Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

161895:CPHO RS01025
gene id: 161895:CPHO_RS01025
uniprot id: A0A1L7D0W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

161895:CPHO RS00285
gene id: 161895:CPHO_RS00285
uniprot id: A0A1L7D0L4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

161895:CPHO RS01685
gene id: 161895:CPHO_RS01685
uniprot id: A0A1L7D1B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

161895:CPHO RS11080
gene id: 161895:CPHO_RS11080
uniprot id: A0A1L7D5V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

161895:CPHO RS07530
gene id: 161895:CPHO_RS07530
uniprot id: A0A1L7D3V1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

161895:CPHO RS02630
gene id: 161895:CPHO_RS02630
uniprot id: A0A1L7D1L6
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

161895:CPHO RS02435
gene id: 161895:CPHO_RS02435
uniprot id: A0A1L7D1F7
names: Similarity
messages: Belongs to the GARS family.

161895:CPHO RS10425
gene id: 161895:CPHO_RS10425
uniprot id: A0A1L7D4Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

161895:CPHO RS03970
gene id: 161895:CPHO_RS03970
uniprot id: A0A1L7D233
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

161895:CPHO RS08945
gene id: 161895:CPHO_RS08945
uniprot id: A0A1L7D476
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

161895:CPHO RS04790
gene id: 161895:CPHO_RS04790
uniprot id: A0A1L7D2U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

161895:CPHO RS05655
gene id: 161895:CPHO_RS05655
uniprot id: A0A1L7D2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

161895:CPHO RS09055
gene id: 161895:CPHO_RS09055
uniprot id: A0A1L7D4R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

161895:CPHO RS06155
gene id: 161895:CPHO_RS06155
uniprot id: A0A1L7D322
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

161895:CPHO RS06185
gene id: 161895:CPHO_RS06185
uniprot id: A0A1L7D307
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

161895:CPHO RS01320
gene id: 161895:CPHO_RS01320
uniprot id: A0A1L7D0U9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

161895:CPHO RS00705
gene id: 161895:CPHO_RS00705
uniprot id: A0A1L7D0Q4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

161895:CPHO RS10725
gene id: 161895:CPHO_RS10725
uniprot id: A0A1L7D5B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161895:CPHO RS04960
gene id: 161895:CPHO_RS04960
uniprot id: A0A1L7D2K6
names: Similarity
messages: Belongs to the MQO family.

161895:CPHO RS03560
gene id: 161895:CPHO_RS03560
uniprot id: A0A1L7D1T3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

161895:CPHO RS07985
gene id: 161895:CPHO_RS07985
uniprot id: A0A1L7D3W8
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS08075
gene id: 161895:CPHO_RS08075
uniprot id: A0A1L7D433
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

161895:CPHO RS02845
gene id: 161895:CPHO_RS02845
uniprot id: A0A1L7D1G2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

161895:CPHO RS12290
gene id: 161895:CPHO_RS12290
uniprot id: A0A1L7D5U9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161895:CPHO RS01055
gene id: 161895:CPHO_RS01055
uniprot id: A0A1L7D0Y0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

161895:CPHO RS06515
gene id: 161895:CPHO_RS06515
uniprot id: A0A1L7D380
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS11820
gene id: 161895:CPHO_RS11820
uniprot id: A0A1L7D680
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

161895:CPHO RS10620
gene id: 161895:CPHO_RS10620
uniprot id: A0A1L7D529
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

161895:CPHO RS06105
gene id: 161895:CPHO_RS06105
uniprot id: A0A1L7D6X2
names: Similarity
messages: Belongs to the UPF0098 family.

161895:CPHO RS10610
gene id: 161895:CPHO_RS10610
uniprot id: A0A1L7D4Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

161895:CPHO RS01080
gene id: 161895:CPHO_RS01080
uniprot id: A0A1L7D136
names: Similarity
messages: Belongs to the catalase family.

161895:CPHO RS06955
gene id: 161895:CPHO_RS06955
uniprot id: A0A1L7D3D1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

161895:CPHO RS04450
gene id: 161895:CPHO_RS04450
uniprot id: A0A1L7D290
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS03155
gene id: 161895:CPHO_RS03155
uniprot id: A0A1L7D1S7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

161895:CPHO RS06930
gene id: 161895:CPHO_RS06930
uniprot id: A0A1L7D3F2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

161895:CPHO RS11210
gene id: 161895:CPHO_RS11210
uniprot id: A0A1L7D5S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS04145
gene id: 161895:CPHO_RS04145
uniprot id: A0A1L7D221
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS02840
gene id: 161895:CPHO_RS02840
uniprot id: A0A1L7D1H5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

161895:CPHO RS10345
gene id: 161895:CPHO_RS10345
uniprot id: A0A1L7D580
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

161895:CPHO RS10320
gene id: 161895:CPHO_RS10320
uniprot id: A0A1L7D4U3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

161895:CPHO RS04635
gene id: 161895:CPHO_RS04635
uniprot id: A0A1L7D2E3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

161895:CPHO RS06600
gene id: 161895:CPHO_RS06600
uniprot id: A0A1L7D3B8
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS12330
gene id: 161895:CPHO_RS12330
uniprot id: A0A1L7D5Z4
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

161895:CPHO RS05280
gene id: 161895:CPHO_RS05280
uniprot id: A0A1L7D2T9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161895:CPHO RS09100
gene id: 161895:CPHO_RS09100
uniprot id: A0A1L7D4F7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

161895:CPHO RS10195
gene id: 161895:CPHO_RS10195
uniprot id: A0A1L7D4V7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

161895:CPHO RS10985
gene id: 161895:CPHO_RS10985
uniprot id: A0A1L7D562
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

161895:CPHO RS02805
gene id: 161895:CPHO_RS02805
uniprot id: A0A1L7D1H7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

161895:CPHO RS05855
gene id: 161895:CPHO_RS05855
uniprot id: A0A1L7D393
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

161895:CPHO RS06545
gene id: 161895:CPHO_RS06545
uniprot id: A0A1L7D3A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

161895:CPHO RS07910
gene id: 161895:CPHO_RS07910
uniprot id: A0A1L7D6J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

161895:CPHO RS11650
gene id: 161895:CPHO_RS11650
uniprot id: A0A1L7D5M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

161895:CPHO RS11890
gene id: 161895:CPHO_RS11890
uniprot id: A0A1L7D5N6
names: Similarity
messages: Belongs to the universal stress protein A family.

161895:CPHO RS09895
gene id: 161895:CPHO_RS09895
uniprot id: A0A1L7D4T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

161895:CPHO RS10055
gene id: 161895:CPHO_RS10055
uniprot id: A0A1L7D4V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

161895:CPHO RS02605
gene id: 161895:CPHO_RS02605
uniprot id: A0A1L7D1M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

161895:CPHO RS10930
gene id: 161895:CPHO_RS10930
uniprot id: A0A1L7D584
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

161895:CPHO RS03595
gene id: 161895:CPHO_RS03595
uniprot id: A0A1L7D2B9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

161895:CPHO RS03320
gene id: 161895:CPHO_RS03320
uniprot id: A0A1L7D1M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

161895:CPHO RS09255
gene id: 161895:CPHO_RS09255
uniprot id: A0A1L7D4Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS02660
gene id: 161895:CPHO_RS02660
uniprot id: A0A1L7D6C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

161895:CPHO RS12320
gene id: 161895:CPHO_RS12320
uniprot id: A0A1L7D5W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

161895:CPHO RS07845
gene id: 161895:CPHO_RS07845
uniprot id: A0A1L7D6E4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

161895:CPHO RS09670
gene id: 161895:CPHO_RS09670
uniprot id: A0A1L7D4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

161895:CPHO RS04685
gene id: 161895:CPHO_RS04685
uniprot id: A0A1L7D2I9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

161895:CPHO RS04630
gene id: 161895:CPHO_RS04630
uniprot id: A0A1L7D676
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

161895:CPHO RS09205
gene id: 161895:CPHO_RS09205
uniprot id: A0A1L7D4H4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS00110
gene id: 161895:CPHO_RS00110
uniprot id: A0A1L7D0C8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

161895:CPHO RS02055
gene id: 161895:CPHO_RS02055
uniprot id: A0A1L7D166
names: Similarity
messages: Belongs to the phosphohexose mutase family.

161895:CPHO RS11230
gene id: 161895:CPHO_RS11230
uniprot id: A0A1L7D5A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

161895:CPHO RS01150
gene id: 161895:CPHO_RS01150
uniprot id: A0A1L7D145
names: Similarity
messages: Belongs to the Nudix hydrolase family.

161895:CPHO RS10795
gene id: 161895:CPHO_RS10795
uniprot id: A0A1L7D764
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

161895:CPHO RS03635
gene id: 161895:CPHO_RS03635
uniprot id: A0A1L7D1Y7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

161895:CPHO RS02720
gene id: 161895:CPHO_RS02720
uniprot id: A0A1L7D1J7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

161895:CPHO RS03280
gene id: 161895:CPHO_RS03280
uniprot id: A0A1L7D1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

161895:CPHO RS03675
gene id: 161895:CPHO_RS03675
uniprot id: A0A1L7D6R6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

161895:CPHO RS01045
gene id: 161895:CPHO_RS01045
uniprot id: A0A1L7D0Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

161895:CPHO RS05605
gene id: 161895:CPHO_RS05605
uniprot id: A0A1L7D2T5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

161895:CPHO RS08825
gene id: 161895:CPHO_RS08825
uniprot id: A0A1L7D460
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

161895:CPHO RS10210
gene id: 161895:CPHO_RS10210
uniprot id: A0A1L7D6L8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

161895:CPHO RS09930
gene id: 161895:CPHO_RS09930
uniprot id: A0A1L7D4N3
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

161895:CPHO RS07890
gene id: 161895:CPHO_RS07890
uniprot id: A0A1L7D3R2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

161895:CPHO RS10215
gene id: 161895:CPHO_RS10215
uniprot id: A0A1L7D559
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS05705
gene id: 161895:CPHO_RS05705
uniprot id: A0A1L7D2X7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

161895:CPHO RS11825
gene id: 161895:CPHO_RS11825
uniprot id: A0A1L7D623
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

161895:CPHO RS07945
gene id: 161895:CPHO_RS07945
uniprot id: A0A1L7D414
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

161895:CPHO RS11225
gene id: 161895:CPHO_RS11225
uniprot id: A0A1L7D5F4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

161895:CPHO RS07725
gene id: 161895:CPHO_RS07725
uniprot id: A0A1L7D3Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

161895:CPHO RS03275
gene id: 161895:CPHO_RS03275
uniprot id: A0A1L7D1S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

161895:CPHO RS01195
gene id: 161895:CPHO_RS01195
uniprot id: A0A1L7D1C1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

161895:CPHO RS10235
gene id: 161895:CPHO_RS10235
uniprot id: A0A1L7D4W0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

161895:CPHO RS12510
gene id: 161895:CPHO_RS12510
uniprot id: A0A1L7D6Z2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

161895:CPHO RS02185
gene id: 161895:CPHO_RS02185
uniprot id: A0A1L7D1D8
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS09625
gene id: 161895:CPHO_RS09625
uniprot id: A0A1L7D513
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

161895:CPHO RS05685
gene id: 161895:CPHO_RS05685
uniprot id: A0A1L7D359
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

161895:CPHO RS02735
gene id: 161895:CPHO_RS02735
uniprot id: A0A1L7D1Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS12530
gene id: 161895:CPHO_RS12530
uniprot id: A0A1L7D629
names: Similarity
messages: Belongs to the ParB family.

161895:CPHO RS09795
gene id: 161895:CPHO_RS09795
uniprot id: A0A1L7D540
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161895:CPHO RS04605
gene id: 161895:CPHO_RS04605
uniprot id: A0A1L7D2G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

161895:CPHO RS04365
gene id: 161895:CPHO_RS04365
uniprot id: A0A1L7D2D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

161895:CPHO RS09175
gene id: 161895:CPHO_RS09175
uniprot id: A0A1L7D4G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cell inner membrane
messages: Membrane

161895:CPHO RS04385
gene id: 161895:CPHO_RS04385
uniprot id: A0A1L7D255
names: Similarity
messages: Belongs to the YggT family.

161895:CPHO RS03860
gene id: 161895:CPHO_RS03860
uniprot id: A0A1L7D257
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

161895:CPHO RS12375
gene id: 161895:CPHO_RS12375
uniprot id: A0A1L7D6R8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

161895:CPHO RS02100
gene id: 161895:CPHO_RS02100
uniprot id: A0A1L7D1P6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

161895:CPHO RS06040
gene id: 161895:CPHO_RS06040
uniprot id: A0A1L7D331
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

161895:CPHO RS04680
gene id: 161895:CPHO_RS04680
uniprot id: A0A1L7D2A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

161895:CPHO RS03890
gene id: 161895:CPHO_RS03890
uniprot id: A0A1L7D2F1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

161895:CPHO RS02900
gene id: 161895:CPHO_RS02900
uniprot id: A0A1L7D1M3
names: Similarity
messages: Belongs to the peptidase S58 family.

161895:CPHO RS06615
gene id: 161895:CPHO_RS06615
uniprot id: A0A1L7D3E6
names: Similarity
messages: Belongs to the universal stress protein A family.

161895:CPHO RS05805
gene id: 161895:CPHO_RS05805
uniprot id: A0A1L7D3F5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS12310
gene id: 161895:CPHO_RS12310
uniprot id: A0A1L7D6F4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161895:CPHO RS05950
gene id: 161895:CPHO_RS05950
uniprot id: A0A1L7D310
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

161895:CPHO RS10460
gene id: 161895:CPHO_RS10460
uniprot id: A0A1L7D531
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

161895:CPHO RS02890
gene id: 161895:CPHO_RS02890
uniprot id: A0A1L7D6L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

161895:CPHO RS10900
gene id: 161895:CPHO_RS10900
uniprot id: A0A1L7D5L7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

161895:CPHO RS05405
gene id: 161895:CPHO_RS05405
uniprot id: A0A1L7D2Q0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

161895:CPHO RS04845
gene id: 161895:CPHO_RS04845
uniprot id: A0A1L7D2I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

161895:CPHO RS03590
gene id: 161895:CPHO_RS03590
uniprot id: A0A1L7D664
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

161895:CPHO RS03880
gene id: 161895:CPHO_RS03880
uniprot id: A0A1L7D235
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

161895:CPHO RS12075
gene id: 161895:CPHO_RS12075
uniprot id: A0A1L7D611
names: Similarity
messages: Belongs to the UPF0371 family.

161895:CPHO RS03250
gene id: 161895:CPHO_RS03250
uniprot id: A0A1L7D1N4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

161895:CPHO RS09580
gene id: 161895:CPHO_RS09580
uniprot id: A0A1L7D4K5
names: Similarity
messages: Belongs to the DEAD box helicase family.

161895:CPHO RS02525
gene id: 161895:CPHO_RS02525
uniprot id: A0A1L7D1W4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

161895:CPHO RS06555
gene id: 161895:CPHO_RS06555
uniprot id: A0A1L7D3U1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

161895:CPHO RS10265
gene id: 161895:CPHO_RS10265
uniprot id: A0A1L7D545
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

161895:CPHO RS03515
gene id: 161895:CPHO_RS03515
uniprot id: A0A1L7D1U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS01340
gene id: 161895:CPHO_RS01340
uniprot id: A0A1L7D112
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

161895:CPHO RS02835
gene id: 161895:CPHO_RS02835
uniprot id: A0A1L7D1L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

161895:CPHO RS05360
gene id: 161895:CPHO_RS05360
uniprot id: A0A1L7D2N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

161895:CPHO RS09340
gene id: 161895:CPHO_RS09340
uniprot id: A0A1L7D4J2
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

161895:CPHO RS08285
gene id: 161895:CPHO_RS08285
uniprot id: A0A1L7D439
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

161895:CPHO RS02910
gene id: 161895:CPHO_RS02910
uniprot id: A0A1L7D1G6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

161895:CPHO RS12460
gene id: 161895:CPHO_RS12460
uniprot id: A0A1L7D5V2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

161895:CPHO RS05830
gene id: 161895:CPHO_RS05830
uniprot id: A0A1L7D2S3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS12305
gene id: 161895:CPHO_RS12305
uniprot id: A0A1L7D652
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

161895:CPHO RS06195
gene id: 161895:CPHO_RS06195
uniprot id: A0A1L7D351
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

161895:CPHO RS12555
gene id: 161895:CPHO_RS12555
uniprot id: A0A1L7D5Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

161895:CPHO RS02310
gene id: 161895:CPHO_RS02310
uniprot id: A0A1L7D1F3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

161895:CPHO RS09925
gene id: 161895:CPHO_RS09925
uniprot id: A0A1L7D4T6
names: Similarity
messages: Belongs to the citrate synthase family.

161895:CPHO RS04905
gene id: 161895:CPHO_RS04905
uniprot id: A0A1L7D2V5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

161895:CPHO RS09415
gene id: 161895:CPHO_RS09415
uniprot id: A0A1L7D4E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

161895:CPHO RS09610
gene id: 161895:CPHO_RS09610
uniprot id: A0A1L7D4P0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

161895:CPHO RS11125
gene id: 161895:CPHO_RS11125
uniprot id: A0A1L7D5B6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

161895:CPHO RS03600
gene id: 161895:CPHO_RS03600
uniprot id: A0A1L7D258
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

161895:CPHO RS02120
gene id: 161895:CPHO_RS02120
uniprot id: A0A1L7D1B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

161895:CPHO RS06750
gene id: 161895:CPHO_RS06750
uniprot id: A0A1L7D3E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

161895:CPHO RS04760
gene id: 161895:CPHO_RS04760
uniprot id: A0A1L7D2J9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

161895:CPHO RS05690
gene id: 161895:CPHO_RS05690
uniprot id: A0A1L7D3D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

161895:CPHO RS04090
gene id: 161895:CPHO_RS04090
uniprot id: A0A1L7D212
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS06560
gene id: 161895:CPHO_RS06560
uniprot id: A0A1L7D3D6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

161895:CPHO RS02670
gene id: 161895:CPHO_RS02670
uniprot id: A0A1L7D1M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

161895:CPHO RS05545
gene id: 161895:CPHO_RS05545
uniprot id: A0A1L7D2U6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

161895:CPHO RS04500
gene id: 161895:CPHO_RS04500
uniprot id: A0A1L7D2G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

161895:CPHO RS11175
gene id: 161895:CPHO_RS11175
uniprot id: A0A1L7D5C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161895:CPHO RS01710
gene id: 161895:CPHO_RS01710
uniprot id: A0A1L7D179
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

161895:CPHO RS09655
gene id: 161895:CPHO_RS09655
uniprot id: A0A1L7D4M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

161895:CPHO RS03475
gene id: 161895:CPHO_RS03475
uniprot id: A0A1L7D238
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

161895:CPHO RS10655
gene id: 161895:CPHO_RS10655
uniprot id: A0A1L7D563
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

161895:CPHO RS10860
gene id: 161895:CPHO_RS10860
uniprot id: A0A1L7D538
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

161895:CPHO RS04260
gene id: 161895:CPHO_RS04260
uniprot id: A0A1L7D281
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

161895:CPHO RS00620
gene id: 161895:CPHO_RS00620
uniprot id: A0A1L7D0Q6
names: Similarity
messages: Belongs to the peptidase M13 family.

161895:CPHO RS09920
gene id: 161895:CPHO_RS09920
uniprot id: A0A1L7D4R2
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

161895:CPHO RS04660
gene id: 161895:CPHO_RS04660
uniprot id: A0A1L7D2H6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

161895:CPHO RS07755
gene id: 161895:CPHO_RS07755
uniprot id: A0A1L7D3S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

161895:CPHO RS01155
gene id: 161895:CPHO_RS01155
uniprot id: A0A1L7D117
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS04595
gene id: 161895:CPHO_RS04595
uniprot id: A0A1L7D2Q7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS10015
gene id: 161895:CPHO_RS10015
uniprot id: A0A1L7D4S6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

161895:CPHO RS08935
gene id: 161895:CPHO_RS08935
uniprot id: A0A1L7D4B3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

161895:CPHO RS11860
gene id: 161895:CPHO_RS11860
uniprot id: A0A1L7D5N4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

161895:CPHO RS04115
gene id: 161895:CPHO_RS04115
uniprot id: A0A1L7D229
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

161895:CPHO RS05530
gene id: 161895:CPHO_RS05530
uniprot id: A0A1L7D2W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

161895:CPHO RS06505
gene id: 161895:CPHO_RS06505
uniprot id: A0A1L7D3T0
names: Similarity
messages: Belongs to the UPF0434 family.

161895:CPHO RS04425
gene id: 161895:CPHO_RS04425
uniprot id: A0A1L7D2B3
names: Similarity
messages: Belongs to the DapA family.

161895:CPHO RS09410
gene id: 161895:CPHO_RS09410
uniprot id: A0A1L7D4K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

161895:CPHO RS05205
gene id: 161895:CPHO_RS05205
uniprot id: A0A1L7D2R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS02610
gene id: 161895:CPHO_RS02610
uniprot id: A0A1L7D1I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

161895:CPHO RS05900
gene id: 161895:CPHO_RS05900
uniprot id: A0A1L7D304
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS04750
gene id: 161895:CPHO_RS04750
uniprot id: A0A1L7D2B5
names: Similarity
messages: Belongs to the P(II) protein family.

161895:CPHO RS06965
gene id: 161895:CPHO_RS06965
uniprot id: A0A1L7D3S7
names: Similarity
messages: Belongs to the HIBADH-related family.

161895:CPHO RS00120
gene id: 161895:CPHO_RS00120
uniprot id: A0A1L7D0X4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

161895:CPHO RS05880
gene id: 161895:CPHO_RS05880
uniprot id: A0A1L7D2T3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

161895:CPHO RS04575
gene id: 161895:CPHO_RS04575
uniprot id: A0A1L7D2G9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

161895:CPHO RS11245
gene id: 161895:CPHO_RS11245
uniprot id: A0A1L7D6Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

161895:CPHO RS09540
gene id: 161895:CPHO_RS09540
uniprot id: A0A1L7D4K7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

161895:CPHO RS04705
gene id: 161895:CPHO_RS04705
uniprot id: A0A1L7D2H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

161895:CPHO RS04690
gene id: 161895:CPHO_RS04690
uniprot id: A0A1L7D694
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS04190
gene id: 161895:CPHO_RS04190
uniprot id: A0A1L7D2A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

161895:CPHO RS04550
gene id: 161895:CPHO_RS04550
uniprot id: A0A1L7D2Q3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

161895:CPHO RS07595
gene id: 161895:CPHO_RS07595
uniprot id: A0A1L7D3N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

161895:CPHO RS01840
gene id: 161895:CPHO_RS01840
uniprot id: A0A1L7D124
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

161895:CPHO RS03130
gene id: 161895:CPHO_RS03130
uniprot id: A0A1L7D1T7
names: Similarity
messages: Belongs to the pirin family.

161895:CPHO RS05055
gene id: 161895:CPHO_RS05055
uniprot id: A0A1L7D2K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

161895:CPHO RS10065
gene id: 161895:CPHO_RS10065
uniprot id: A0A1L7D754
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

161895:CPHO RS12070
gene id: 161895:CPHO_RS12070
uniprot id: A0A1L7D5T8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

161895:CPHO RS07440
gene id: 161895:CPHO_RS07440
uniprot id: A0A1L7D3T4
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS02665
gene id: 161895:CPHO_RS02665
uniprot id: A0A1L7D1S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

161895:CPHO RS06745
gene id: 161895:CPHO_RS06745
uniprot id: A0A1L7D3C3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

161895:CPHO RS06215
gene id: 161895:CPHO_RS06215
uniprot id: A0A1L7D3N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

161895:CPHO RS03375
gene id: 161895:CPHO_RS03375
uniprot id: A0A1L7D1U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

161895:CPHO RS01425
gene id: 161895:CPHO_RS01425
uniprot id: A0A1L7D1F2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

161895:CPHO RS09020
gene id: 161895:CPHO_RS09020
uniprot id: A0A1L7D4J6
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS04085
gene id: 161895:CPHO_RS04085
uniprot id: A0A1L7D252
names: Similarity
messages: Belongs to the glutamine synthetase family.

161895:CPHO RS09210
gene id: 161895:CPHO_RS09210
uniprot id: A0A1L7D4B2
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

161895:CPHO RS03425
gene id: 161895:CPHO_RS03425
uniprot id: A0A1L7D1Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

161895:CPHO RS01140
gene id: 161895:CPHO_RS01140
uniprot id: A0A1L7D0Y4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

161895:CPHO RS02255
gene id: 161895:CPHO_RS02255
uniprot id: A0A1L7D192
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

161895:CPHO RS11975
gene id: 161895:CPHO_RS11975
uniprot id: A0A1L7D5L9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

161895:CPHO RS09715
gene id: 161895:CPHO_RS09715
uniprot id: A0A1L7D4L0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

161895:CPHO RS05485
gene id: 161895:CPHO_RS05485
uniprot id: A0A1L7D3A4
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

161895:CPHO RS05135
gene id: 161895:CPHO_RS05135
uniprot id: A0A1L7D2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

161895:CPHO RS01380
gene id: 161895:CPHO_RS01380
uniprot id: A0A1L7D141
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

161895:CPHO RS00955
gene id: 161895:CPHO_RS00955
uniprot id: A0A1L7D116
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

161895:CPHO RS05710
gene id: 161895:CPHO_RS05710
uniprot id: A0A1L7D2Q2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

161895:CPHO RS01330
gene id: 161895:CPHO_RS01330
uniprot id: A0A1L7D0U8
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

161895:CPHO RS06320
gene id: 161895:CPHO_RS06320
uniprot id: A0A1L7D3G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

161895:CPHO RS02285
gene id: 161895:CPHO_RS02285
uniprot id: A0A1L7D196
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

161895:CPHO RS02770
gene id: 161895:CPHO_RS02770
uniprot id: A0A1L7D1F0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

161895:CPHO RS06915
gene id: 161895:CPHO_RS06915
uniprot id: A0A1L7D3R6
names: Similarity
messages: Belongs to the histone deacetylase family.

161895:CPHO RS07610
gene id: 161895:CPHO_RS07610
uniprot id: A0A1L7D4A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

161895:CPHO RS12260
gene id: 161895:CPHO_RS12260
uniprot id: A0A1L7D696
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

161895:CPHO RS08875
gene id: 161895:CPHO_RS08875
uniprot id: A0A1L7D4A4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

161895:CPHO RS09995
gene id: 161895:CPHO_RS09995
uniprot id: A0A1L7D4V0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS08730
gene id: 161895:CPHO_RS08730
uniprot id: A0A1L7D464
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

161895:CPHO RS08305
gene id: 161895:CPHO_RS08305
uniprot id: A0A1L7D406
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

161895:CPHO RS05230
gene id: 161895:CPHO_RS05230
uniprot id: A0A1L7D2S9
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS07730
gene id: 161895:CPHO_RS07730
uniprot id: A0A1L7D3U6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

161895:CPHO RS00150
gene id: 161895:CPHO_RS00150
uniprot id: A0A1L7D0D0
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS06525
gene id: 161895:CPHO_RS06525
uniprot id: A0A1L7D339
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS04220
gene id: 161895:CPHO_RS04220
uniprot id: A0A1L7D682
names: Similarity
messages: Belongs to the peptidase C40 family.

161895:CPHO RS08740
gene id: 161895:CPHO_RS08740
uniprot id: A0A1L7D4K3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS04390
gene id: 161895:CPHO_RS04390
uniprot id: A0A1L7D2E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

161895:CPHO RS06010
gene id: 161895:CPHO_RS06010
uniprot id: A0A1L7D320
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

161895:CPHO RS09395
gene id: 161895:CPHO_RS09395
uniprot id: A0A1L7D4X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

161895:CPHO RS01740
gene id: 161895:CPHO_RS01740
uniprot id: A0A1L7D167
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS07555
gene id: 161895:CPHO_RS07555
uniprot id: A0A1L7D491
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

161895:CPHO RS03335
gene id: 161895:CPHO_RS03335
uniprot id: A0A1L7D1T8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

161895:CPHO RS02355
gene id: 161895:CPHO_RS02355
uniprot id: A0A1L7D1H0
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

161895:CPHO RS01850
gene id: 161895:CPHO_RS01850
uniprot id: A0A1L7D183
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS04005
gene id: 161895:CPHO_RS04005
uniprot id: A0A1L7D2G5
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

161895:CPHO RS13095
gene id: 161895:CPHO_RS13095
uniprot id: A0A1L7D653
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

161895:CPHO RS08995
gene id: 161895:CPHO_RS08995
uniprot id: A0A1L7D4Q6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

161895:CPHO RS10630
gene id: 161895:CPHO_RS10630
uniprot id: A0A1L7D557
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

161895:CPHO RS00015
gene id: 161895:CPHO_RS00015
uniprot id: A0A1L7D0A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

161895:CPHO RS02765
gene id: 161895:CPHO_RS02765
uniprot id: A0A1L7D1G4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

161895:CPHO RS10790
gene id: 161895:CPHO_RS10790
uniprot id: A0A1L7D525
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

161895:CPHO RS10110
gene id: 161895:CPHO_RS10110
uniprot id: A0A1L7D587
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

161895:CPHO RS12175
gene id: 161895:CPHO_RS12175
uniprot id: A0A1L7D5T3
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS04555
gene id: 161895:CPHO_RS04555
uniprot id: A0A1L7D2G1
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

161895:CPHO RS07745
gene id: 161895:CPHO_RS07745
uniprot id: A0A1L7D3Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

161895:CPHO RS00845
gene id: 161895:CPHO_RS00845
uniprot id: A0A1L7D0U3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

161895:CPHO RS07630
gene id: 161895:CPHO_RS07630
uniprot id: A0A1L7D3M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

161895:CPHO RS01645
gene id: 161895:CPHO_RS01645
uniprot id: A0A1L7D0Z0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS04395
gene id: 161895:CPHO_RS04395
uniprot id: A0A1L7D2A3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

161895:CPHO RS04980
gene id: 161895:CPHO_RS04980
uniprot id: A0A1L7D2I4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

161895:CPHO RS00640
gene id: 161895:CPHO_RS00640
uniprot id: A0A1L7D0T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

161895:CPHO RS07855
gene id: 161895:CPHO_RS07855
uniprot id: A0A1L7D461
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

161895:CPHO RS07935
gene id: 161895:CPHO_RS07935
uniprot id: A0A1L7D469
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS05945
gene id: 161895:CPHO_RS05945
uniprot id: A0A1L7D2X0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS02980
gene id: 161895:CPHO_RS02980
uniprot id: A0A1L7D1R6
names: Similarity
messages: Belongs to the peptidase S33 family.

161895:CPHO RS10810
gene id: 161895:CPHO_RS10810
uniprot id: A0A1L7D5C7
names: Similarity
messages: Belongs to the pantothenate synthetase family.

161895:CPHO RS02725
gene id: 161895:CPHO_RS02725
uniprot id: A0A1L7D1G5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

161895:CPHO RS10470
gene id: 161895:CPHO_RS10470
uniprot id: A0A1L7D5A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

161895:CPHO RS06530
gene id: 161895:CPHO_RS06530
uniprot id: A0A1L7D3D7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

161895:CPHO RS09520
gene id: 161895:CPHO_RS09520
uniprot id: A0A1L7D4J5
names: Similarity
messages: Belongs to the peptidase S16 family.

161895:CPHO RS05785
gene id: 161895:CPHO_RS05785
uniprot id: A0A1L7D2W4
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

161895:CPHO RS10365
gene id: 161895:CPHO_RS10365
uniprot id: A0A1L7D504
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

161895:CPHO RS11985
gene id: 161895:CPHO_RS11985
uniprot id: A0A1L7D5Q4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS04950
gene id: 161895:CPHO_RS04950
uniprot id: A0A1L7D2I3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

161895:CPHO RS00710
gene id: 161895:CPHO_RS00710
uniprot id: A0A1L7D6K1
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS02790
gene id: 161895:CPHO_RS02790
uniprot id: A0A1L7D1N3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

161895:CPHO RS00130
gene id: 161895:CPHO_RS00130
uniprot id: A0A1L7D0L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

161895:CPHO RS04730
gene id: 161895:CPHO_RS04730
uniprot id: A0A1L7D2T1
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS06065
gene id: 161895:CPHO_RS06065
uniprot id: A0A1L7D332
names: Similarity
messages: Belongs to the peptidase C40 family.

161895:CPHO RS03120
gene id: 161895:CPHO_RS03120
uniprot id: A0A1L7D1J5
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS10370
gene id: 161895:CPHO_RS10370
uniprot id: A0A1L7D4V5
names: Similarity
messages: Belongs to the WXG100 family.

161895:CPHO RS09755
gene id: 161895:CPHO_RS09755
uniprot id: A0A1L7D6K8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

161895:CPHO RS00335
gene id: 161895:CPHO_RS00335
uniprot id: A0A1L7D0K4
names: Similarity
messages: Belongs to the LOG family.

161895:CPHO RS02650
gene id: 161895:CPHO_RS02650
uniprot id: A0A1L7D1K1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

161895:CPHO RS00325
gene id: 161895:CPHO_RS00325
uniprot id: A0A1L7D0F5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

161895:CPHO RS01725
gene id: 161895:CPHO_RS01725
uniprot id: A0A1L7D109
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

161895:CPHO RS02215
gene id: 161895:CPHO_RS02215
uniprot id: A0A1L7D1K4
names: Similarity
messages: Belongs to the Nth/MutY family.

161895:CPHO RS02620
gene id: 161895:CPHO_RS02620
uniprot id: A0A1L7D1D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

161895:CPHO RS07245
gene id: 161895:CPHO_RS07245
uniprot id: A0A1L7D444
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

161895:CPHO RS11405
gene id: 161895:CPHO_RS11405
uniprot id: A0A1L7D5E8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

161895:CPHO RS00375
gene id: 161895:CPHO_RS00375
uniprot id: A0A1L7D0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS10715
gene id: 161895:CPHO_RS10715
uniprot id: A0A1L7D517
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

161895:CPHO RS05820
gene id: 161895:CPHO_RS05820
uniprot id: A0A1L7D2W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

161895:CPHO RS04810
gene id: 161895:CPHO_RS04810
uniprot id: A0A1L7D6U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

161895:CPHO RS06115
gene id: 161895:CPHO_RS06115
uniprot id: A0A1L7D366
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

161895:CPHO RS04445
gene id: 161895:CPHO_RS04445
uniprot id: A0A1L7D2B6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

161895:CPHO RS04925
gene id: 161895:CPHO_RS04925
uniprot id: A0A1L7D2H5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

161895:CPHO RS01440
gene id: 161895:CPHO_RS01440
uniprot id: A0A1L7D181
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS07365
gene id: 161895:CPHO_RS07365
uniprot id: A0A1L7D466
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

161895:CPHO RS03625
gene id: 161895:CPHO_RS03625
uniprot id: A0A1L7D227
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

161895:CPHO RS09780
gene id: 161895:CPHO_RS09780
uniprot id: A0A1L7D4R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

161895:CPHO RS02445
gene id: 161895:CPHO_RS02445
uniprot id: A0A1L7D1H3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

161895:CPHO RS10360
gene id: 161895:CPHO_RS10360
uniprot id: A0A1L7D4Y0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

161895:CPHO RS11325
gene id: 161895:CPHO_RS11325
uniprot id: A0A1L7D5H5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

161895:CPHO RS00105
gene id: 161895:CPHO_RS00105
uniprot id: A0A1L7D0E7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

161895:CPHO RS12515
gene id: 161895:CPHO_RS12515
uniprot id: A0A1L7D6D9
names: Similarity
messages: Belongs to the thioredoxin family.

161895:CPHO RS08230
gene id: 161895:CPHO_RS08230
uniprot id: A0A1L7D6H0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS00950
gene id: 161895:CPHO_RS00950
uniprot id: A0A1L7D182
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

161895:CPHO RS04340
gene id: 161895:CPHO_RS04340
uniprot id: A0A1L7D291
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

161895:CPHO RS02640
gene id: 161895:CPHO_RS02640
uniprot id: A0A1L7D1I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

161895:CPHO RS02290
gene id: 161895:CPHO_RS02290
uniprot id: A0A1L7D185
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

161895:CPHO RS01700
gene id: 161895:CPHO_RS01700
uniprot id: A0A1L7D626
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

161895:CPHO RS03390
gene id: 161895:CPHO_RS03390
uniprot id: A0A1L7D1X8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

161895:CPHO RS08950
gene id: 161895:CPHO_RS08950
uniprot id: A0A1L7D6T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

161895:CPHO RS02520
gene id: 161895:CPHO_RS02520
uniprot id: A0A1L7D1I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

161895:CPHO RS05420
gene id: 161895:CPHO_RS05420
uniprot id: A0A1L7D2V9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

161895:CPHO RS10415
gene id: 161895:CPHO_RS10415
uniprot id: A0A1L7D5K0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

161895:CPHO RS05125
gene id: 161895:CPHO_RS05125
uniprot id: A0A1L7D2Z1
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS09440
gene id: 161895:CPHO_RS09440
uniprot id: A0A1L7D4T5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

161895:CPHO RS09740
gene id: 161895:CPHO_RS09740
uniprot id: A0A1L7D533
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

161895:CPHO RS07650
gene id: 161895:CPHO_RS07650
uniprot id: A0A1L7D3P1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

161895:CPHO RS07625
gene id: 161895:CPHO_RS07625
uniprot id: A0A1L7D3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

161895:CPHO RS04870
gene id: 161895:CPHO_RS04870
uniprot id: A0A1L7D2J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

161895:CPHO RS08220
gene id: 161895:CPHO_RS08220
uniprot id: A0A1L7D427
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS04895
gene id: 161895:CPHO_RS04895
uniprot id: A0A1L7D2J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

161895:CPHO RS05615
gene id: 161895:CPHO_RS05615
uniprot id: A0A1L7D6W1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

161895:CPHO RS10480
gene id: 161895:CPHO_RS10480
uniprot id: A0A1L7D5E9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

161895:CPHO RS02655
gene id: 161895:CPHO_RS02655
uniprot id: A0A1L7D1Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

161895:CPHO RS04140
gene id: 161895:CPHO_RS04140
uniprot id: A0A1L7D260
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

161895:CPHO RS07585
gene id: 161895:CPHO_RS07585
uniprot id: A0A1L7D3V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

161895:CPHO RS05780
gene id: 161895:CPHO_RS05780
uniprot id: A0A1L7D309
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

161895:CPHO RS01205
gene id: 161895:CPHO_RS01205
uniprot id: A0A1L7D126
names: Similarity
messages: Belongs to the GSP E family.

161895:CPHO RS08145
gene id: 161895:CPHO_RS08145
uniprot id: A0A1L7D4I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

161895:CPHO RS07435
gene id: 161895:CPHO_RS07435
uniprot id: A0A1L7D474
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS10475
gene id: 161895:CPHO_RS10475
uniprot id: A0A1L7D5K9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

161895:CPHO RS10155
gene id: 161895:CPHO_RS10155
uniprot id: A0A1L7D4X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

161895:CPHO RS11980
gene id: 161895:CPHO_RS11980
uniprot id: A0A1L7D5X0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

161895:CPHO RS01310
gene id: 161895:CPHO_RS01310
uniprot id: A0A1L7D131
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

161895:CPHO RS05935
gene id: 161895:CPHO_RS05935
uniprot id: A0A1L7D335
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

161895:CPHO RS02995
gene id: 161895:CPHO_RS02995
uniprot id: A0A1L7D1L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

161895:CPHO RS06470
gene id: 161895:CPHO_RS06470
uniprot id: A0A1L7D3C7
names: Similarity
messages: Belongs to the TlyA family.

161895:CPHO RS06830
gene id: 161895:CPHO_RS06830
uniprot id: A0A1L7D3I9
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

161895:CPHO RS02125
gene id: 161895:CPHO_RS02125
uniprot id: A0A1L7D174
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

161895:CPHO RS07510
gene id: 161895:CPHO_RS07510
uniprot id: A0A1L7D3R4
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

161895:CPHO RS04455
gene id: 161895:CPHO_RS04455
uniprot id: A0A1L7D2D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161895:CPHO RS07870
gene id: 161895:CPHO_RS07870
uniprot id: A0A1L7D402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

161895:CPHO RS12325
gene id: 161895:CPHO_RS12325
uniprot id: A0A1L7D6P9
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS04625
gene id: 161895:CPHO_RS04625
uniprot id: A0A1L7D2H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

161895:CPHO RS05675
gene id: 161895:CPHO_RS05675
uniprot id: A0A1L7D2S2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

161895:CPHO RS06590
gene id: 161895:CPHO_RS06590
uniprot id: A0A1L7D399
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

161895:CPHO RS01250
gene id: 161895:CPHO_RS01250
uniprot id: A0A1L7D651
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

161895:CPHO RS06640
gene id: 161895:CPHO_RS06640
uniprot id: A0A1L7D6T9
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS06180
gene id: 161895:CPHO_RS06180
uniprot id: A0A1L7D328
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

161895:CPHO RS00420
gene id: 161895:CPHO_RS00420
uniprot id: A0A1L7D0G6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

161895:CPHO RS04135
gene id: 161895:CPHO_RS04135
uniprot id: A0A1L7D295
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

161895:CPHO RS00985
gene id: 161895:CPHO_RS00985
uniprot id: A0A1L7D0Y9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

161895:CPHO RS06620
gene id: 161895:CPHO_RS06620
uniprot id: A0A1L7D3A2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

161895:CPHO RS04355
gene id: 161895:CPHO_RS04355
uniprot id: A0A1L7D2L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

161895:CPHO RS05385
gene id: 161895:CPHO_RS05385
uniprot id: A0A1L7D394
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

161895:CPHO RS02960
gene id: 161895:CPHO_RS02960
uniprot id: A0A1L7D1J6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

161895:CPHO RS06290
gene id: 161895:CPHO_RS06290
uniprot id: A0A1L7D367
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

161895:CPHO RS03205
gene id: 161895:CPHO_RS03205
uniprot id: A0A1L7D1K5
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

161895:CPHO RS02850
gene id: 161895:CPHO_RS02850
uniprot id: A0A1L7D1P3
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

161895:CPHO RS04305
gene id: 161895:CPHO_RS04305
uniprot id: A0A1L7D2L4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

161895:CPHO RS05930
gene id: 161895:CPHO_RS05930
uniprot id: A0A1L7D2U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

161895:CPHO RS06500
gene id: 161895:CPHO_RS06500
uniprot id: A0A1L7D3J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

161895:CPHO RS05040
gene id: 161895:CPHO_RS05040
uniprot id: A0A1L7D2M4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

161895:CPHO RS10070
gene id: 161895:CPHO_RS10070
uniprot id: A0A1L7D518
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

161895:CPHO RS06405
gene id: 161895:CPHO_RS06405
uniprot id: A0A1L7D319
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

161895:CPHO RS03220
gene id: 161895:CPHO_RS03220
uniprot id: A0A1L7D1N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

161895:CPHO RS08250
gene id: 161895:CPHO_RS08250
uniprot id: A0A1L7D426
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

161895:CPHO RS08225
gene id: 161895:CPHO_RS08225
uniprot id: A0A1L7D3W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

161895:CPHO RS03790
gene id: 161895:CPHO_RS03790
uniprot id: A0A1L7D207
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

161895:CPHO RS07615
gene id: 161895:CPHO_RS07615
uniprot id: A0A1L7D3W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

161895:CPHO RS09095
gene id: 161895:CPHO_RS09095
uniprot id: A0A1L7D4B8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

161895:CPHO RS09660
gene id: 161895:CPHO_RS09660
uniprot id: A0A1L7D4K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

161895:CPHO RS05800
gene id: 161895:CPHO_RS05800
uniprot id: A0A1L7D385
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

161895:CPHO RS03645
gene id: 161895:CPHO_RS03645
uniprot id: A0A1L7D203
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

161895:CPHO RS03340
gene id: 161895:CPHO_RS03340
uniprot id: A0A1L7D1Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

161895:CPHO RS09875
gene id: 161895:CPHO_RS09875
uniprot id: A0A1L7D4L6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

161895:CPHO RS10405
gene id: 161895:CPHO_RS10405
uniprot id: A0A1L7D590
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS05240
gene id: 161895:CPHO_RS05240
uniprot id: A0A1L7D2L1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

161895:CPHO RS09615
gene id: 161895:CPHO_RS09615
uniprot id: A0A1L7D4W4
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

161895:CPHO RS04420
gene id: 161895:CPHO_RS04420
uniprot id: A0A1L7D2E4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

161895:CPHO RS05735
gene id: 161895:CPHO_RS05735
uniprot id: A0A1L7D373
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

161895:CPHO RS10730
gene id: 161895:CPHO_RS10730
uniprot id: A0A1L7D550
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

161895:CPHO RS02555
gene id: 161895:CPHO_RS02555
uniprot id: A0A1L7D1C3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

161895:CPHO RS08165
gene id: 161895:CPHO_RS08165
uniprot id: A0A1L7D3U8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

161895:CPHO RS09725
gene id: 161895:CPHO_RS09725
uniprot id: A0A1L7D702
names: Similarity
messages: Belongs to the phosphohexose mutase family.

161895:CPHO RS09990
gene id: 161895:CPHO_RS09990
uniprot id: A0A1L7D4S1
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS01790
gene id: 161895:CPHO_RS01790
uniprot id: A0A1L7D105
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS00830
gene id: 161895:CPHO_RS00830
uniprot id: A0A1L7D0S5
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

161895:CPHO RS07475
gene id: 161895:CPHO_RS07475
uniprot id: A0A1L7D3L1
names: Similarity
messages: Belongs to the CsoR family.

161895:CPHO RS04120
gene id: 161895:CPHO_RS04120
uniprot id: A0A1L7D273
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

161895:CPHO RS05715
gene id: 161895:CPHO_RS05715
uniprot id: A0A1L7D300
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS06070
gene id: 161895:CPHO_RS06070
uniprot id: A0A1L7D3C9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS04480
gene id: 161895:CPHO_RS04480
uniprot id: A0A1L7D2C1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

161895:CPHO RS10230
gene id: 161895:CPHO_RS10230
uniprot id: A0A1L7D5A7
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

161895:CPHO RS05580
gene id: 161895:CPHO_RS05580
uniprot id: A0A1L7D2S0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

161895:CPHO RS04920
gene id: 161895:CPHO_RS04920
uniprot id: A0A1L7D2L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

161895:CPHO RS10285
gene id: 161895:CPHO_RS10285
uniprot id: A0A1L7D569
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

161895:CPHO RS02060
gene id: 161895:CPHO_RS02060
uniprot id: A0A1L7D151
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

161895:CPHO RS06890
gene id: 161895:CPHO_RS06890
uniprot id: A0A1L7D3K1
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS08115
gene id: 161895:CPHO_RS08115
uniprot id: A0A1L7D3Y8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

161895:CPHO RS08100
gene id: 161895:CPHO_RS08100
uniprot id: A0A1L7D6Q7
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS04150
gene id: 161895:CPHO_RS04150
uniprot id: A0A1L7D211
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

161895:CPHO RS04330
gene id: 161895:CPHO_RS04330
uniprot id: A0A1L7D246
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

161895:CPHO RS00320
gene id: 161895:CPHO_RS00320
uniprot id: A0A1L7D0J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

161895:CPHO RS11945
gene id: 161895:CPHO_RS11945
uniprot id: A0A1L7D5Z2
names: Similarity
messages: Belongs to the PspA/IM30 family.

161895:CPHO RS08830
gene id: 161895:CPHO_RS08830
uniprot id: A0A1L7D4G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

161895:CPHO RS02645
gene id: 161895:CPHO_RS02645
uniprot id: A0A1L7D1F4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

161895:CPHO RS09315
gene id: 161895:CPHO_RS09315
uniprot id: A0A1L7D4R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

161895:CPHO RS09040
gene id: 161895:CPHO_RS09040
uniprot id: A0A1L7D4M7
names: Similarity
messages: Belongs to the FPG family.

161895:CPHO RS10585
gene id: 161895:CPHO_RS10585
uniprot id: A0A1L7D5N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

161895:CPHO RS03270
gene id: 161895:CPHO_RS03270
uniprot id: A0A1L7D1V7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

161895:CPHO RS06685
gene id: 161895:CPHO_RS06685
uniprot id: A0A1L7D3B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS08850
gene id: 161895:CPHO_RS08850
uniprot id: A0A1L7D6I7
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS12205
gene id: 161895:CPHO_RS12205
uniprot id: A0A1L7D5X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

161895:CPHO RS02580
gene id: 161895:CPHO_RS02580
uniprot id: A0A1L7D1J1
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

161895:CPHO RS07455
gene id: 161895:CPHO_RS07455
uniprot id: A0A1L7D3Q4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

161895:CPHO RS06650
gene id: 161895:CPHO_RS06650
uniprot id: A0A1L7D3B0
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS05245
gene id: 161895:CPHO_RS05245
uniprot id: A0A1L7D2Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

161895:CPHO RS05100
gene id: 161895:CPHO_RS05100
uniprot id: A0A1L7D2G6
names: Similarity
messages: Belongs to the YciI family.

161895:CPHO RS00990
gene id: 161895:CPHO_RS00990
uniprot id: A0A1L7D0U5
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS01170
gene id: 161895:CPHO_RS01170
uniprot id: A0A1L7D0S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS00440
gene id: 161895:CPHO_RS00440
uniprot id: A0A1L7D0Q2
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

161895:CPHO RS00795
gene id: 161895:CPHO_RS00795
uniprot id: A0A1L7D0M2
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

161895:CPHO RS03185
gene id: 161895:CPHO_RS03185
uniprot id: A0A1L7D1U5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

161895:CPHO RS06575
gene id: 161895:CPHO_RS06575
uniprot id: A0A1L7D349
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

161895:CPHO RS05960
gene id: 161895:CPHO_RS05960
uniprot id: A0A1L7D3I5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

161895:CPHO RS10115
gene id: 161895:CPHO_RS10115
uniprot id: A0A1L7D4U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS11885
gene id: 161895:CPHO_RS11885
uniprot id: A0A1L7D633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

161895:CPHO RS03055
gene id: 161895:CPHO_RS03055
uniprot id: A0A1L7D1I5
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS03285
gene id: 161895:CPHO_RS03285
uniprot id: A0A1L7D1U6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

161895:CPHO RS02930
gene id: 161895:CPHO_RS02930
uniprot id: A0A1L7D1P5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

161895:CPHO RS08000
gene id: 161895:CPHO_RS08000
uniprot id: A0A1L7D481
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

161895:CPHO RS11515
gene id: 161895:CPHO_RS11515
uniprot id: A0A1L7D5J5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS06760
gene id: 161895:CPHO_RS06760
uniprot id: A0A1L7D3H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

161895:CPHO RS02440
gene id: 161895:CPHO_RS02440
uniprot id: A0A1L7D1C0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

161895:CPHO RS12100
gene id: 161895:CPHO_RS12100
uniprot id: A0A1L7D5P1
names: Subcellular Location Annotation
messages: Membrane

161895:CPHO RS03585
gene id: 161895:CPHO_RS03585
uniprot id: A0A1L7D1Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

161895:CPHO RS00330
gene id: 161895:CPHO_RS00330
uniprot id: A0A1L7D0F4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-68 and Arg-71) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

161895:CPHO RS12505
gene id: 161895:CPHO_RS12505
uniprot id: A0A1L7D6I1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161895:CPHO RS02260
gene id: 161895:CPHO_RS02260
uniprot id: A0A1L7D1D7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161895:CPHO RS02625
gene id: 161895:CPHO_RS02625
uniprot id: A0A1L7D627
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

161895:CPHO RS05225
gene id: 161895:CPHO_RS05225
uniprot id: A0A1L7D2I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

161895:CPHO RS04735
gene id: 161895:CPHO_RS04735
uniprot id: A0A1L7D2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

161895:CPHO RS03530
gene id: 161895:CPHO_RS03530
uniprot id: A0A1L7D2A9
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

161895:CPHO RS10520
gene id: 161895:CPHO_RS10520
uniprot id: A0A1L7D5B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

161895:CPHO RS02865
gene id: 161895:CPHO_RS02865
uniprot id: A0A1L7D1N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

161895:CPHO RS02455
gene id: 161895:CPHO_RS02455
uniprot id: A0A1L7D1P1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

161895:CPHO RS05320
gene id: 161895:CPHO_RS05320
uniprot id: A0A1L7D2P0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.