1616788:AR543 RS18030
gene id: 1616788:AR543_RS18030
uniprot id: A0A172ZKB1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1616788:AR543 RS12805
gene id: 1616788:AR543_RS12805
uniprot id: A0A172ZGL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

1616788:AR543 RS01305
gene id: 1616788:AR543_RS01305
uniprot id: A0A172ZBA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS21550
gene id: 1616788:AR543_RS21550
uniprot id: A0A172ZKX2
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS16975
gene id: 1616788:AR543_RS16975
uniprot id: A0A172ZIZ4
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1616788:AR543 RS11600
gene id: 1616788:AR543_RS11600
uniprot id: A0A172ZM98
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1616788:AR543 RS09505
gene id: 1616788:AR543_RS09505
uniprot id: A0A172ZG03
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS18470
gene id: 1616788:AR543_RS18470
uniprot id: A0A172ZJK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1616788:AR543 RS08730
gene id: 1616788:AR543_RS08730
uniprot id: A0A172ZFY1
names: Subcellular Location Annotation
messages: Cell membrane

1616788:AR543 RS03615
gene id: 1616788:AR543_RS03615
uniprot id: A0A172ZCE9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1616788:AR543 RS20330
gene id: 1616788:AR543_RS20330
uniprot id: A0A172ZKE0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1616788:AR543 RS14695
gene id: 1616788:AR543_RS14695
uniprot id: A0A172ZHP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1616788:AR543 RS02395
gene id: 1616788:AR543_RS02395
uniprot id: A0A172ZCV7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS03040
gene id: 1616788:AR543_RS03040
uniprot id: A0A172ZBW2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1616788:AR543 RS22100
gene id: 1616788:AR543_RS22100
uniprot id: A0A172ZMN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1616788:AR543 RS07925
gene id: 1616788:AR543_RS07925
uniprot id: A0A172ZE45
names: Cofactor
messages: Binds 1 FAD per subunit.

1616788:AR543 RS07750
gene id: 1616788:AR543_RS07750
uniprot id: A0A172ZE16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1616788:AR543 RS21715
gene id: 1616788:AR543_RS21715
uniprot id: A0A172ZKZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1616788:AR543 RS22900
gene id: 1616788:AR543_RS22900
uniprot id: A0A172ZLL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1616788:AR543 RS03545
gene id: 1616788:AR543_RS03545
uniprot id: A0A172ZC14
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1616788:AR543 RS09310
gene id: 1616788:AR543_RS09310
uniprot id: A0A172ZMB8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1616788:AR543 RS19755
gene id: 1616788:AR543_RS19755
uniprot id: A0A172ZLJ5
names: Similarity
messages: Belongs to the UPF0297 family.

1616788:AR543 RS17545
gene id: 1616788:AR543_RS17545
uniprot id: A0A172ZJ95
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1616788:AR543 RS03045
gene id: 1616788:AR543_RS03045
uniprot id: A0A172ZC51
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1616788:AR543 RS15145
gene id: 1616788:AR543_RS15145
uniprot id: A0A172ZHT0
names: Similarity
messages: Belongs to the peptidase M20A family.

1616788:AR543 RS09380
gene id: 1616788:AR543_RS09380
uniprot id: A0A172ZEU7
names: Similarity
messages: Belongs to the ArsC family.

1616788:AR543 RS07560
gene id: 1616788:AR543_RS07560
uniprot id: A0A172ZF05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

1616788:AR543 RS17930
gene id: 1616788:AR543_RS17930
uniprot id: A0A172ZML6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1616788:AR543 RS17060
gene id: 1616788:AR543_RS17060
uniprot id: A0A172ZIQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1616788:AR543 RS14420
gene id: 1616788:AR543_RS14420
uniprot id: A0A172ZI32
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1616788:AR543 RS02695
gene id: 1616788:AR543_RS02695
uniprot id: A0A172ZCQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS14685
gene id: 1616788:AR543_RS14685
uniprot id: A0A172ZHK4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1616788:AR543 RS22385
gene id: 1616788:AR543_RS22385
uniprot id: A0A172ZM00
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1616788:AR543 RS03190
gene id: 1616788:AR543_RS03190
uniprot id: A0A172ZBW1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1616788:AR543 RS00860
gene id: 1616788:AR543_RS00860
uniprot id: A0A172ZAQ9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1616788:AR543 RS22105
gene id: 1616788:AR543_RS22105
uniprot id: A0A172ZL57
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1616788:AR543 RS00545
gene id: 1616788:AR543_RS00545
uniprot id: A0A172ZAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1616788:AR543 RS16765
gene id: 1616788:AR543_RS16765
uniprot id: A0A172ZIK8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1616788:AR543 RS17985
gene id: 1616788:AR543_RS17985
uniprot id: A0A172ZJH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

1616788:AR543 RS08605
gene id: 1616788:AR543_RS08605
uniprot id: A0A172ZEF8
names: Similarity
messages: Belongs to the GSP E family.

1616788:AR543 RS16890
gene id: 1616788:AR543_RS16890
uniprot id: A0A172ZIT3
names: Similarity
messages: Belongs to the peptidase U62 family.

1616788:AR543 RS22595
gene id: 1616788:AR543_RS22595
uniprot id: A0A172ZM38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1616788:AR543 RS09605
gene id: 1616788:AR543_RS09605
uniprot id: A0A172ZF00
names: Similarity
messages: Belongs to the EamA transporter family.

1616788:AR543 RS04975
gene id: 1616788:AR543_RS04975
uniprot id: A0A172ZCP2
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS05640
gene id: 1616788:AR543_RS05640
uniprot id: A0A172ZD07
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1616788:AR543 RS21515
gene id: 1616788:AR543_RS21515
uniprot id: A0A172ZL31
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1616788:AR543 RS16800
gene id: 1616788:AR543_RS16800
uniprot id: A0A172ZJA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1616788:AR543 RS04335
gene id: 1616788:AR543_RS04335
uniprot id: A0A172ZCE3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1616788:AR543 RS19745
gene id: 1616788:AR543_RS19745
uniprot id: A0A172ZK82
names: Similarity
messages: Belongs to the UPF0473 family.

1616788:AR543 RS19440
gene id: 1616788:AR543_RS19440
uniprot id: A0A172ZJZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1616788:AR543 RS08895
gene id: 1616788:AR543_RS08895
uniprot id: A0A172ZG16
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1616788:AR543 RS05620
gene id: 1616788:AR543_RS05620
uniprot id: A0A172ZDU1
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS09580
gene id: 1616788:AR543_RS09580
uniprot id: A0A172ZFR8
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS20120
gene id: 1616788:AR543_RS20120
uniprot id: A0A172ZKA4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1616788:AR543 RS00615
gene id: 1616788:AR543_RS00615
uniprot id: A0A172ZBN6
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1616788:AR543 RS08270
gene id: 1616788:AR543_RS08270
uniprot id: A0A172ZEA9
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1616788:AR543 RS05815
gene id: 1616788:AR543_RS05815
uniprot id: A0A172ZD27
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1616788:AR543 RS22400
gene id: 1616788:AR543_RS22400
uniprot id: A0A172ZLA2
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

1616788:AR543 RS12505
gene id: 1616788:AR543_RS12505
uniprot id: A0A172ZHH2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS22130
gene id: 1616788:AR543_RS22130
uniprot id: A0A172ZL75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1616788:AR543 RS20975
gene id: 1616788:AR543_RS20975
uniprot id: A0A172ZKQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS19930
gene id: 1616788:AR543_RS19930
uniprot id: A0A172ZKV7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1616788:AR543 RS06550
gene id: 1616788:AR543_RS06550
uniprot id: A0A172ZDG4
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS17555
gene id: 1616788:AR543_RS17555
uniprot id: A0A172ZJ01
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS21685
gene id: 1616788:AR543_RS21685
uniprot id: A0A172ZLA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS10590
gene id: 1616788:AR543_RS10590
uniprot id: A0A172ZFI1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1616788:AR543 RS16730
gene id: 1616788:AR543_RS16730
uniprot id: A0A172ZIQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1616788:AR543 RS20100
gene id: 1616788:AR543_RS20100
uniprot id: A0A172ZLQ3
names: Similarity
messages: Belongs to the UPF0758 family.

1616788:AR543 RS05395
gene id: 1616788:AR543_RS05395
uniprot id: A0A172ZE04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1616788:AR543 RS22745
gene id: 1616788:AR543_RS22745
uniprot id: A0A172ZLH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1616788:AR543 RS22895
gene id: 1616788:AR543_RS22895
uniprot id: A0A172ZN00
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1616788:AR543 RS05015
gene id: 1616788:AR543_RS05015
uniprot id: A0A172ZCQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS04205
gene id: 1616788:AR543_RS04205
uniprot id: A0A172ZD61
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS16430
gene id: 1616788:AR543_RS16430
uniprot id: A0A172ZIE6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS16495
gene id: 1616788:AR543_RS16495
uniprot id: A0A172ZIL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS10675
gene id: 1616788:AR543_RS10675
uniprot id: A0A172ZGZ6
names: Similarity
messages: Belongs to the barstar family.

1616788:AR543 RS09415
gene id: 1616788:AR543_RS09415
uniprot id: A0A172ZGC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1616788:AR543 RS06840
gene id: 1616788:AR543_RS06840
uniprot id: A0A172ZDX7
names: Similarity
messages: Belongs to the GSP E family.

1616788:AR543 RS17590
gene id: 1616788:AR543_RS17590
uniprot id: A0A172ZJ47
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1616788:AR543 RS11550
gene id: 1616788:AR543_RS11550
uniprot id: A0A172ZGZ8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1616788:AR543 RS04905
gene id: 1616788:AR543_RS04905
uniprot id: A0A172ZCN0
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1616788:AR543 RS10860
gene id: 1616788:AR543_RS10860
uniprot id: A0A172ZH20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1616788:AR543 RS19330
gene id: 1616788:AR543_RS19330
uniprot id: A0A172ZK68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS13610
gene id: 1616788:AR543_RS13610
uniprot id: A0A172ZH14
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS03395
gene id: 1616788:AR543_RS03395
uniprot id: A0A172ZCB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1616788:AR543 RS09970
gene id: 1616788:AR543_RS09970
uniprot id: A0A172ZF46
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS17740
gene id: 1616788:AR543_RS17740
uniprot id: A0A172ZK59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1616788:AR543 RS13660
gene id: 1616788:AR543_RS13660
uniprot id: A0A172ZH13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS22270
gene id: 1616788:AR543_RS22270
uniprot id: A0A172ZL94
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1616788:AR543 RS04025
gene id: 1616788:AR543_RS04025
uniprot id: A0A172ZD32
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS21850
gene id: 1616788:AR543_RS21850
uniprot id: A0A172ZM86
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1616788:AR543 RS14430
gene id: 1616788:AR543_RS14430
uniprot id: A0A172ZHF1
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1616788:AR543 RS02320
gene id: 1616788:AR543_RS02320
uniprot id: A0A172ZCI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS08835
gene id: 1616788:AR543_RS08835
uniprot id: A0A172ZEY0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1616788:AR543 RS08280
gene id: 1616788:AR543_RS08280
uniprot id: A0A172ZER5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1616788:AR543 RS09430
gene id: 1616788:AR543_RS09430
uniprot id: A0A172ZFA1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1616788:AR543 RS21075
gene id: 1616788:AR543_RS21075
uniprot id: A0A172ZM82
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS07870
gene id: 1616788:AR543_RS07870
uniprot id: A0A172ZE36
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS13740
gene id: 1616788:AR543_RS13740
uniprot id: A0A172ZH28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1616788:AR543 RS10405
gene id: 1616788:AR543_RS10405
uniprot id: A0A172ZG50
names: Subcellular Location Annotation
messages: Cytoplasm

1616788:AR543 RS05010
gene id: 1616788:AR543_RS05010
uniprot id: A0A172ZE61
names: Similarity
messages: Belongs to the RutC family.

1616788:AR543 RS10840
gene id: 1616788:AR543_RS10840
uniprot id: A0A172ZFQ3
names: Similarity
messages: Belongs to the peptidase S8 family.

1616788:AR543 RS16715
gene id: 1616788:AR543_RS16715
uniprot id: A0A172ZIJ8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1616788:AR543 RS20205
gene id: 1616788:AR543_RS20205
uniprot id: A0A172ZLS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1616788:AR543 RS20245
gene id: 1616788:AR543_RS20245
uniprot id: A0A172ZKC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

1616788:AR543 RS14035
gene id: 1616788:AR543_RS14035
uniprot id: A0A172ZH84
names: Similarity
messages: Belongs to the peptidase S8 family.

1616788:AR543 RS02515
gene id: 1616788:AR543_RS02515
uniprot id: A0A172ZCB5
names: Subcellular Location Annotation
messages: Mitochondrion

1616788:AR543 RS16600
gene id: 1616788:AR543_RS16600
uniprot id: A0A172ZJJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1616788:AR543 RS22145
gene id: 1616788:AR543_RS22145
uniprot id: A0A172ZLG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1616788:AR543 RS22835
gene id: 1616788:AR543_RS22835
uniprot id: A0A172ZLQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1616788:AR543 RS06965
gene id: 1616788:AR543_RS06965
uniprot id: A0A172ZE38
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1616788:AR543 RS22960
gene id: 1616788:AR543_RS22960
uniprot id: A0A172ZLW7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1616788:AR543 RS07770
gene id: 1616788:AR543_RS07770
uniprot id: A0A172ZE39
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1616788:AR543 RS16950
gene id: 1616788:AR543_RS16950
uniprot id: A0A172ZIZ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1616788:AR543 RS17980
gene id: 1616788:AR543_RS17980
uniprot id: A0A172ZJB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1616788:AR543 RS13075
gene id: 1616788:AR543_RS13075
uniprot id: A0A172ZH27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS06285
gene id: 1616788:AR543_RS06285
uniprot id: A0A172ZEQ5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1616788:AR543 RS21080
gene id: 1616788:AR543_RS21080
uniprot id: A0A172ZKR5
names: Similarity
messages: Belongs to the PspA/IM30 family.

1616788:AR543 RS01685
gene id: 1616788:AR543_RS01685
uniprot id: A0A172ZB48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1616788:AR543 RS18080
gene id: 1616788:AR543_RS18080
uniprot id: A0A172ZKC0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1616788:AR543 RS02885
gene id: 1616788:AR543_RS02885
uniprot id: A0A172ZCJ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1616788:AR543 RS12835
gene id: 1616788:AR543_RS12835
uniprot id: A0A172ZGK7
names: Similarity
messages: Belongs to the histone deacetylase family.

1616788:AR543 RS03570
gene id: 1616788:AR543_RS03570
uniprot id: A0A172ZC28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1616788:AR543 RS13180
gene id: 1616788:AR543_RS13180
uniprot id: A0A172ZHH1
names: Similarity
messages: Belongs to the ThiD family.

1616788:AR543 RS09755
gene id: 1616788:AR543_RS09755
uniprot id: A0A172ZF21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1616788:AR543 RS07710
gene id: 1616788:AR543_RS07710
uniprot id: A0A172ZE09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS15070
gene id: 1616788:AR543_RS15070
uniprot id: A0A172ZI11
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1616788:AR543 RS07885
gene id: 1616788:AR543_RS07885
uniprot id: A0A172ZE43
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS16935
gene id: 1616788:AR543_RS16935
uniprot id: A0A172ZIN0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1616788:AR543 RS20885
gene id: 1616788:AR543_RS20885
uniprot id: A0A172ZKT8
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS20135
gene id: 1616788:AR543_RS20135
uniprot id: A0A172ZKB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS13750
gene id: 1616788:AR543_RS13750
uniprot id: A0A172ZH34
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1616788:AR543 RS02420
gene id: 1616788:AR543_RS02420
uniprot id: A0A172ZBH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

1616788:AR543 RS15985
gene id: 1616788:AR543_RS15985
uniprot id: A0A172ZI71
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS04355
gene id: 1616788:AR543_RS04355
uniprot id: A0A172ZCH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1616788:AR543 RS16920
gene id: 1616788:AR543_RS16920
uniprot id: A0A172ZIY4
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1616788:AR543 RS11395
gene id: 1616788:AR543_RS11395
uniprot id: A0A172ZFX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1616788:AR543 RS07955
gene id: 1616788:AR543_RS07955
uniprot id: A0A172ZF82
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1616788:AR543 RS21485
gene id: 1616788:AR543_RS21485
uniprot id: A0A172ZLK3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1616788:AR543 RS07800
gene id: 1616788:AR543_RS07800
uniprot id: A0A172ZE26
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1616788:AR543 RS09560
gene id: 1616788:AR543_RS09560
uniprot id: A0A172ZF13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS19890
gene id: 1616788:AR543_RS19890
uniprot id: A0A172ZK87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1616788:AR543 RS22020
gene id: 1616788:AR543_RS22020
uniprot id: A0A172ZL54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1616788:AR543 RS10260
gene id: 1616788:AR543_RS10260
uniprot id: A0A172ZF91
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS09800
gene id: 1616788:AR543_RS09800
uniprot id: A0A172ZGJ5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1616788:AR543 RS16310
gene id: 1616788:AR543_RS16310
uniprot id: A0A172ZJ20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1616788:AR543 RS06715
gene id: 1616788:AR543_RS06715
uniprot id: A0A172ZEL6
names: Similarity
messages: Belongs to the GSP E family.

1616788:AR543 RS15470
gene id: 1616788:AR543_RS15470
uniprot id: A0A172ZIM3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1616788:AR543 RS14795
gene id: 1616788:AR543_RS14795
uniprot id: A0A172ZIL5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1616788:AR543 RS05125
gene id: 1616788:AR543_RS05125
uniprot id: A0A172ZD44
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS24680
gene id: 1616788:AR543_RS24680
uniprot id: A0A172ZM58
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1616788:AR543 RS19055
gene id: 1616788:AR543_RS19055
uniprot id: A0A172ZJR7
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1616788:AR543 RS16575
gene id: 1616788:AR543_RS16575
uniprot id: A0A172ZIS5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS06655
gene id: 1616788:AR543_RS06655
uniprot id: A0A172ZDI1
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS03575
gene id: 1616788:AR543_RS03575
uniprot id: A0A172ZLS5
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1616788:AR543 RS00285
gene id: 1616788:AR543_RS00285
uniprot id: A0A172ZAG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1616788:AR543 RS05585
gene id: 1616788:AR543_RS05585
uniprot id: A0A172ZM73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS11565
gene id: 1616788:AR543_RS11565
uniprot id: A0A172ZHE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1616788:AR543 RS21570
gene id: 1616788:AR543_RS21570
uniprot id: A0A172ZL82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1616788:AR543 RS00680
gene id: 1616788:AR543_RS00680
uniprot id: A0A172ZAP6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1616788:AR543 RS08890
gene id: 1616788:AR543_RS08890
uniprot id: A0A172ZND2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1616788:AR543 RS17550
gene id: 1616788:AR543_RS17550
uniprot id: A0A172ZKE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1616788:AR543 RS11165
gene id: 1616788:AR543_RS11165
uniprot id: A0A172ZNH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1616788:AR543 RS16875
gene id: 1616788:AR543_RS16875
uniprot id: A0A172ZIM9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1616788:AR543 RS05895
gene id: 1616788:AR543_RS05895
uniprot id: A0A172ZD47
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1616788:AR543 RS06020
gene id: 1616788:AR543_RS06020
uniprot id: A0A172ZEA8
names: Similarity
messages: Belongs to the colicins ColE2/ColE8/ColE9 and pyocins S1/S2 family.

1616788:AR543 RS03690
gene id: 1616788:AR543_RS03690
uniprot id: A0A172ZCI3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1616788:AR543 RS22680
gene id: 1616788:AR543_RS22680
uniprot id: A0A172ZLM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1616788:AR543 RS09335
gene id: 1616788:AR543_RS09335
uniprot id: A0A172ZEV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1616788:AR543 RS14880
gene id: 1616788:AR543_RS14880
uniprot id: A0A172ZHX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS07410
gene id: 1616788:AR543_RS07410
uniprot id: A0A172ZEP1
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1616788:AR543 RS16635
gene id: 1616788:AR543_RS16635
uniprot id: A0A172ZJ77
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1616788:AR543 RS06345
gene id: 1616788:AR543_RS06345
uniprot id: A0A172ZDB3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1616788:AR543 RS10655
gene id: 1616788:AR543_RS10655
uniprot id: A0A172ZMH3
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1616788:AR543 RS17710
gene id: 1616788:AR543_RS17710
uniprot id: A0A172ZJ29
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS22935
gene id: 1616788:AR543_RS22935
uniprot id: A0A172ZLM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS15295
gene id: 1616788:AR543_RS15295
uniprot id: A0A172ZJB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1616788:AR543 RS20270
gene id: 1616788:AR543_RS20270
uniprot id: A0A172ZLG2
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

1616788:AR543 RS21425
gene id: 1616788:AR543_RS21425
uniprot id: A0A172ZKV0
names: Subcellular Location Annotation
messages: cell wall

1616788:AR543 RS08415
gene id: 1616788:AR543_RS08415
uniprot id: A0A172ZFH2
names: Similarity
messages: Belongs to the GbsR family.

1616788:AR543 RS22765
gene id: 1616788:AR543_RS22765
uniprot id: A0A172ZLI0
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS22880
gene id: 1616788:AR543_RS22880
uniprot id: A0A172ZMS0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1616788:AR543 RS12670
gene id: 1616788:AR543_RS12670
uniprot id: A0A172ZGJ0
names: Similarity
messages: Belongs to the hyi family.

1616788:AR543 RS12895
gene id: 1616788:AR543_RS12895
uniprot id: A0A172ZGL9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1616788:AR543 RS15760
gene id: 1616788:AR543_RS15760
uniprot id: A0A172ZI25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS17895
gene id: 1616788:AR543_RS17895
uniprot id: A0A172ZJF3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS03095
gene id: 1616788:AR543_RS03095
uniprot id: A0A172ZC61
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1616788:AR543 RS17035
gene id: 1616788:AR543_RS17035
uniprot id: A0A172ZIR2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1616788:AR543 RS13780
gene id: 1616788:AR543_RS13780
uniprot id: A0A172ZHS1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1616788:AR543 RS11675
gene id: 1616788:AR543_RS11675
uniprot id: A0A172ZH26
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1616788:AR543 RS15485
gene id: 1616788:AR543_RS15485
uniprot id: A0A172ZHY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1616788:AR543 RS08480
gene id: 1616788:AR543_RS08480
uniprot id: A0A172ZEG1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1616788:AR543 RS07320
gene id: 1616788:AR543_RS07320
uniprot id: A0A172ZDV4
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1616788:AR543 RS10350
gene id: 1616788:AR543_RS10350
uniprot id: A0A172ZG40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1616788:AR543 RS03600
gene id: 1616788:AR543_RS03600
uniprot id: A0A172ZC26
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS17100
gene id: 1616788:AR543_RS17100
uniprot id: A0A172ZJ14
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1616788:AR543 RS11850
gene id: 1616788:AR543_RS11850
uniprot id: A0A172ZG55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS06245
gene id: 1616788:AR543_RS06245
uniprot id: A0A172ZE30
names: Similarity
messages: Belongs to the UPF0111 family.

1616788:AR543 RS22905
gene id: 1616788:AR543_RS22905
uniprot id: A0A172ZM97
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS02755
gene id: 1616788:AR543_RS02755
uniprot id: A0A172ZC02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1616788:AR543 RS16620
gene id: 1616788:AR543_RS16620
uniprot id: A0A172ZJY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1616788:AR543 RS05715
gene id: 1616788:AR543_RS05715
uniprot id: A0A172ZD19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS19895
gene id: 1616788:AR543_RS19895
uniprot id: A0A172ZLA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1616788:AR543 RS05330
gene id: 1616788:AR543_RS05330
uniprot id: A0A172ZCW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1616788:AR543 RS06280
gene id: 1616788:AR543_RS06280
uniprot id: A0A172ZDN7
names: Function
names: Similarity
messages: Belongs to the acyltransferase CrtO family.
messages: Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i.e. the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin. This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains.

1616788:AR543 RS12285
gene id: 1616788:AR543_RS12285
uniprot id: A0A172ZGH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS20070
gene id: 1616788:AR543_RS20070
uniprot id: A0A172ZK94
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS11770
gene id: 1616788:AR543_RS11770
uniprot id: A0A172ZGS7
names: Similarity
messages: Belongs to the HesB/IscA family.

1616788:AR543 RS02665
gene id: 1616788:AR543_RS02665
uniprot id: A0A172ZBL9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1616788:AR543 RS01515
gene id: 1616788:AR543_RS01515
uniprot id: A0A172ZB16
names: Similarity
messages: Belongs to the FGGY kinase family.

1616788:AR543 RS13525
gene id: 1616788:AR543_RS13525
uniprot id: A0A172ZIE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS11895
gene id: 1616788:AR543_RS11895
uniprot id: A0A172ZG53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS07510
gene id: 1616788:AR543_RS07510
uniprot id: A0A172ZEA4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1616788:AR543 RS15190
gene id: 1616788:AR543_RS15190
uniprot id: A0A172ZHT4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS22045
gene id: 1616788:AR543_RS22045
uniprot id: A0A172ZL48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1616788:AR543 RS17975
gene id: 1616788:AR543_RS17975
uniprot id: A0A172ZK99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1616788:AR543 RS18630
gene id: 1616788:AR543_RS18630
uniprot id: A0A172ZJU8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1616788:AR543 RS17540
gene id: 1616788:AR543_RS17540
uniprot id: A0A172ZML9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1616788:AR543 RS21230
gene id: 1616788:AR543_RS21230
uniprot id: A0A172ZMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1616788:AR543 RS07935
gene id: 1616788:AR543_RS07935
uniprot id: A0A172ZEK9
names: Similarity
messages: Belongs to the peptidase M29 family.

1616788:AR543 RS18330
gene id: 1616788:AR543_RS18330
uniprot id: A0A172ZJD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1616788:AR543 RS11480
gene id: 1616788:AR543_RS11480
uniprot id: A0A172ZGB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1616788:AR543 RS02815
gene id: 1616788:AR543_RS02815
uniprot id: A0A172ZD42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1616788:AR543 RS17940
gene id: 1616788:AR543_RS17940
uniprot id: A0A172ZJ72
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1616788:AR543 RS04290
gene id: 1616788:AR543_RS04290
uniprot id: A0A172ZCD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1616788:AR543 RS04240
gene id: 1616788:AR543_RS04240
uniprot id: A0A172ZCC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1616788:AR543 RS13120
gene id: 1616788:AR543_RS13120
uniprot id: A0A172ZHG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS18120
gene id: 1616788:AR543_RS18120
uniprot id: A0A172ZJ99
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS12790
gene id: 1616788:AR543_RS12790
uniprot id: A0A172ZHA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS01715
gene id: 1616788:AR543_RS01715
uniprot id: A0A172ZB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS18520
gene id: 1616788:AR543_RS18520
uniprot id: A0A172ZKK5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1616788:AR543 RS11150
gene id: 1616788:AR543_RS11150
uniprot id: A0A172ZGH3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1616788:AR543 RS15250
gene id: 1616788:AR543_RS15250
uniprot id: A0A172ZI47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS00305
gene id: 1616788:AR543_RS00305
uniprot id: A0A172ZAG6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1616788:AR543 RS22985
gene id: 1616788:AR543_RS22985
uniprot id: A0A172ZLW6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1616788:AR543 RS03555
gene id: 1616788:AR543_RS03555
uniprot id: A0A172ZC50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1616788:AR543 RS01075
gene id: 1616788:AR543_RS01075
uniprot id: A0A172ZAU9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1616788:AR543 RS23385
gene id: 1616788:AR543_RS23385
uniprot id: A0A1X9T400
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1616788:AR543 RS14535
gene id: 1616788:AR543_RS14535
uniprot id: A0A172ZI55
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1616788:AR543 RS22875
gene id: 1616788:AR543_RS22875
uniprot id: A0A172ZLL5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1616788:AR543 RS10470
gene id: 1616788:AR543_RS10470
uniprot id: A0A172ZFC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

1616788:AR543 RS23370
gene id: 1616788:AR543_RS23370
uniprot id: A0A1X9T462
names: Similarity
messages: Belongs to the transposase 7 family.

1616788:AR543 RS12290
gene id: 1616788:AR543_RS12290
uniprot id: A0A172ZGN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS03580
gene id: 1616788:AR543_RS03580
uniprot id: A0A172ZCW1
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1616788:AR543 RS11440
gene id: 1616788:AR543_RS11440
uniprot id: A0A172ZFX4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1616788:AR543 RS02920
gene id: 1616788:AR543_RS02920
uniprot id: A0A172ZBU3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1616788:AR543 RS08850
gene id: 1616788:AR543_RS08850
uniprot id: A0A172ZFC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1616788:AR543 RS22815
gene id: 1616788:AR543_RS22815
uniprot id: A0A172ZLJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS19550
gene id: 1616788:AR543_RS19550
uniprot id: A0A172ZK03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1616788:AR543 RS09475
gene id: 1616788:AR543_RS09475
uniprot id: A0A172ZEX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS07970
gene id: 1616788:AR543_RS07970
uniprot id: A0A172ZFK7
names: Subcellular Location Annotation
messages: Cytoplasm

1616788:AR543 RS01405
gene id: 1616788:AR543_RS01405
uniprot id: A0A172ZB00
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS23860
gene id: 1616788:AR543_RS23860
uniprot id: A0A1X9T4E7
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

1616788:AR543 RS05525
gene id: 1616788:AR543_RS05525
uniprot id: A0A172ZCY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1616788:AR543 RS16960
gene id: 1616788:AR543_RS16960
uniprot id: A0A172ZK43
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1616788:AR543 RS20060
gene id: 1616788:AR543_RS20060
uniprot id: A0A172ZKW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1616788:AR543 RS10605
gene id: 1616788:AR543_RS10605
uniprot id: A0A172ZFS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS20900
gene id: 1616788:AR543_RS20900
uniprot id: A0A172ZKN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS02310
gene id: 1616788:AR543_RS02310
uniprot id: A0A172ZBE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

1616788:AR543 RS08345
gene id: 1616788:AR543_RS08345
uniprot id: A0A172ZEC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1616788:AR543 RS17920
gene id: 1616788:AR543_RS17920
uniprot id: A0A172ZJA8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1616788:AR543 RS10730
gene id: 1616788:AR543_RS10730
uniprot id: A0A172ZH06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS23390
gene id: 1616788:AR543_RS23390
uniprot id: A0A1X9T423
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS08275
gene id: 1616788:AR543_RS08275
uniprot id: A0A172ZF39
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1616788:AR543 RS12115
gene id: 1616788:AR543_RS12115
uniprot id: A0A172ZHA7
names: Similarity
messages: Belongs to the DinB family.

1616788:AR543 RS07635
gene id: 1616788:AR543_RS07635
uniprot id: A0A172ZDZ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1616788:AR543 RS03700
gene id: 1616788:AR543_RS03700
uniprot id: A0A172ZC42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1616788:AR543 RS22885
gene id: 1616788:AR543_RS22885
uniprot id: A0A172ZLR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS02185
gene id: 1616788:AR543_RS02185
uniprot id: A0A172ZBD5
names: Similarity
messages: Belongs to the darcynin family.

1616788:AR543 RS01225
gene id: 1616788:AR543_RS01225
uniprot id: A0A172ZAX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1616788:AR543 RS11520
gene id: 1616788:AR543_RS11520
uniprot id: A0A172ZFX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1616788:AR543 RS03400
gene id: 1616788:AR543_RS03400
uniprot id: A0A172ZDD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1616788:AR543 RS20625
gene id: 1616788:AR543_RS20625
uniprot id: A0A172ZKS7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS06815
gene id: 1616788:AR543_RS06815
uniprot id: A0A172ZDJ4
names: Function
messages: Required for transformation and DNA binding.

1616788:AR543 RS21995
gene id: 1616788:AR543_RS21995
uniprot id: A0A172ZLS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1616788:AR543 RS17050
gene id: 1616788:AR543_RS17050
uniprot id: A0A172ZMK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1616788:AR543 RS20030
gene id: 1616788:AR543_RS20030
uniprot id: A0A172ZK97
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1616788:AR543 RS15960
gene id: 1616788:AR543_RS15960
uniprot id: A0A172ZIH4
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS19495
gene id: 1616788:AR543_RS19495
uniprot id: A0A172ZK05
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1616788:AR543 RS22620
gene id: 1616788:AR543_RS22620
uniprot id: A0A172ZMM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1616788:AR543 RS21490
gene id: 1616788:AR543_RS21490
uniprot id: A0A172ZL63
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1616788:AR543 RS16440
gene id: 1616788:AR543_RS16440
uniprot id: A0A172ZJG5
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

1616788:AR543 RS20635
gene id: 1616788:AR543_RS20635
uniprot id: A0A172ZKH9
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS16155
gene id: 1616788:AR543_RS16155
uniprot id: A0A172ZIA1
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1616788:AR543 RS02875
gene id: 1616788:AR543_RS02875
uniprot id: A0A172ZD50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1616788:AR543 RS16615
gene id: 1616788:AR543_RS16615
uniprot id: A0A172ZIT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS22660
gene id: 1616788:AR543_RS22660
uniprot id: A0A172ZLG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1616788:AR543 RS15430
gene id: 1616788:AR543_RS15430
uniprot id: A0A172ZHX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1616788:AR543 RS11250
gene id: 1616788:AR543_RS11250
uniprot id: A0A172ZFX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1616788:AR543 RS18185
gene id: 1616788:AR543_RS18185
uniprot id: A0A172ZKE5
names: Similarity
messages: Belongs to the UPF0178 family.

1616788:AR543 RS05215
gene id: 1616788:AR543_RS05215
uniprot id: A0A172ZCU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

1616788:AR543 RS21975
gene id: 1616788:AR543_RS21975
uniprot id: A0A172ZLA0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS05460
gene id: 1616788:AR543_RS05460
uniprot id: A0A172ZCY6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1616788:AR543 RS00935
gene id: 1616788:AR543_RS00935
uniprot id: A0A172ZAS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS08260
gene id: 1616788:AR543_RS08260
uniprot id: A0A172ZEP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS13560
gene id: 1616788:AR543_RS13560
uniprot id: A0A172ZH00
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1616788:AR543 RS01100
gene id: 1616788:AR543_RS01100
uniprot id: A0A172ZAV1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1616788:AR543 RS20990
gene id: 1616788:AR543_RS20990
uniprot id: A0A172ZLV3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1616788:AR543 RS08295
gene id: 1616788:AR543_RS08295
uniprot id: A0A172ZEB8
names: Similarity
messages: Belongs to the glutamate synthase family.

1616788:AR543 RS00205
gene id: 1616788:AR543_RS00205
uniprot id: A0A172ZBH2
names: Similarity
messages: Belongs to the pirin family.

1616788:AR543 RS21380
gene id: 1616788:AR543_RS21380
uniprot id: A0A172ZKU8
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS19505
gene id: 1616788:AR543_RS19505
uniprot id: A0A172ZK13
names: Similarity
messages: Belongs to the FGGY kinase family.

1616788:AR543 RS06805
gene id: 1616788:AR543_RS06805
uniprot id: A0A172ZED1
names: Similarity
messages: Belongs to the DCK/DGK family.

1616788:AR543 RS08030
gene id: 1616788:AR543_RS08030
uniprot id: A0A172ZEZ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS09420
gene id: 1616788:AR543_RS09420
uniprot id: A0A172ZEW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1616788:AR543 RS17935
gene id: 1616788:AR543_RS17935
uniprot id: A0A172ZKL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1616788:AR543 RS10920
gene id: 1616788:AR543_RS10920
uniprot id: A0A172ZFM8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1616788:AR543 RS22115
gene id: 1616788:AR543_RS22115
uniprot id: A0A172ZLG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1616788:AR543 RS22570
gene id: 1616788:AR543_RS22570
uniprot id: A0A172ZML0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1616788:AR543 RS21970
gene id: 1616788:AR543_RS21970
uniprot id: A0A172ZM95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1616788:AR543 RS05910
gene id: 1616788:AR543_RS05910
uniprot id: A0A172ZDI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1616788:AR543 RS04715
gene id: 1616788:AR543_RS04715
uniprot id: A0A172ZE24
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1616788:AR543 RS10365
gene id: 1616788:AR543_RS10365
uniprot id: A0A172ZFE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

1616788:AR543 RS18565
gene id: 1616788:AR543_RS18565
uniprot id: A0A172ZJH7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1616788:AR543 RS05900
gene id: 1616788:AR543_RS05900
uniprot id: A0A172ZE88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1616788:AR543 RS04790
gene id: 1616788:AR543_RS04790
uniprot id: A0A172ZDF9
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS14300
gene id: 1616788:AR543_RS14300
uniprot id: A0A172ZHC6
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

1616788:AR543 RS09455
gene id: 1616788:AR543_RS09455
uniprot id: A0A172ZFZ0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS06430
gene id: 1616788:AR543_RS06430
uniprot id: A0A172ZDT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS16650
gene id: 1616788:AR543_RS16650
uniprot id: A0A172ZII8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1616788:AR543 RS07995
gene id: 1616788:AR543_RS07995
uniprot id: A0A172ZE76
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS15710
gene id: 1616788:AR543_RS15710
uniprot id: A0A172ZI22
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS09330
gene id: 1616788:AR543_RS09330
uniprot id: A0A172ZEU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1616788:AR543 RS20685
gene id: 1616788:AR543_RS20685
uniprot id: A0A172ZM06
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1616788:AR543 RS14200
gene id: 1616788:AR543_RS14200
uniprot id: A0A172ZHL0
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1616788:AR543 RS14740
gene id: 1616788:AR543_RS14740
uniprot id: A0A172ZMQ3
names: Cofactor
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Autophosphorylated.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1616788:AR543 RS09425
gene id: 1616788:AR543_RS09425
uniprot id: A0A172ZFN8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1616788:AR543 RS22035
gene id: 1616788:AR543_RS22035
uniprot id: A0A172ZLF0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1616788:AR543 RS09795
gene id: 1616788:AR543_RS09795
uniprot id: A0A172ZFE1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1616788:AR543 RS19715
gene id: 1616788:AR543_RS19715
uniprot id: A0A172ZKD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1616788:AR543 RS13585
gene id: 1616788:AR543_RS13585
uniprot id: A0A172ZIF9
names: Similarity
messages: Belongs to the FBPase class 2 family.

1616788:AR543 RS03855
gene id: 1616788:AR543_RS03855
uniprot id: A0A172ZC77
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1616788:AR543 RS07060
gene id: 1616788:AR543_RS07060
uniprot id: A0A172ZF45
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS04575
gene id: 1616788:AR543_RS04575
uniprot id: A0A172ZE01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1616788:AR543 RS02855
gene id: 1616788:AR543_RS02855
uniprot id: A0A172ZBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1616788:AR543 RS09990
gene id: 1616788:AR543_RS09990
uniprot id: A0A172ZFA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1616788:AR543 RS17690
gene id: 1616788:AR543_RS17690
uniprot id: A0A172ZK49
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1616788:AR543 RS21955
gene id: 1616788:AR543_RS21955
uniprot id: A0A172ZL36
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1616788:AR543 RS18310
gene id: 1616788:AR543_RS18310
uniprot id: A0A172ZJE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS01435
gene id: 1616788:AR543_RS01435
uniprot id: A0A172ZBS5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS10775
gene id: 1616788:AR543_RS10775
uniprot id: A0A172ZFP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1616788:AR543 RS08990
gene id: 1616788:AR543_RS08990
uniprot id: A0A172ZER3
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS19815
gene id: 1616788:AR543_RS19815
uniprot id: A0A172ZK50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1616788:AR543 RS11935
gene id: 1616788:AR543_RS11935
uniprot id: A0A172ZGJ4
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1616788:AR543 RS20040
gene id: 1616788:AR543_RS20040
uniprot id: A0A172ZKC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1616788:AR543 RS05250
gene id: 1616788:AR543_RS05250
uniprot id: A0A172ZDN5
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS11100
gene id: 1616788:AR543_RS11100
uniprot id: A0A172ZGG3
names: Similarity
messages: Belongs to the fabD family.

1616788:AR543 RS20655
gene id: 1616788:AR543_RS20655
uniprot id: A0A172ZKI1
names: Similarity
messages: Belongs to the EamA transporter family.

1616788:AR543 RS17630
gene id: 1616788:AR543_RS17630
uniprot id: A0A172ZMT8
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS13880
gene id: 1616788:AR543_RS13880
uniprot id: A0A172ZIL3
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS13865
gene id: 1616788:AR543_RS13865
uniprot id: A0A172ZHA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

1616788:AR543 RS02990
gene id: 1616788:AR543_RS02990
uniprot id: A0A172ZC41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

1616788:AR543 RS09450
gene id: 1616788:AR543_RS09450
uniprot id: A0A172ZEX1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1616788:AR543 RS03375
gene id: 1616788:AR543_RS03375
uniprot id: A0A172ZBZ1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1616788:AR543 RS12020
gene id: 1616788:AR543_RS12020
uniprot id: A0A172ZGC1
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS21540
gene id: 1616788:AR543_RS21540
uniprot id: A0A172ZL73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1616788:AR543 RS07405
gene id: 1616788:AR543_RS07405
uniprot id: A0A172ZM08
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS12040
gene id: 1616788:AR543_RS12040
uniprot id: A0A172ZGW6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1616788:AR543 RS21260
gene id: 1616788:AR543_RS21260
uniprot id: A0A172ZL29
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS19540
gene id: 1616788:AR543_RS19540
uniprot id: A0A172ZKA7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS10165
gene id: 1616788:AR543_RS10165
uniprot id: A0A172ZGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS12025
gene id: 1616788:AR543_RS12025
uniprot id: A0A172ZGI9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS10425
gene id: 1616788:AR543_RS10425
uniprot id: A0A172ZFF5
names: Subcellular Location Annotation
messages: Cell membrane

1616788:AR543 RS05155
gene id: 1616788:AR543_RS05155
uniprot id: A0A172ZCT3
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS19910
gene id: 1616788:AR543_RS19910
uniprot id: A0A172ZKH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1616788:AR543 RS19555
gene id: 1616788:AR543_RS19555
uniprot id: A0A172ZK27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1616788:AR543 RS04545
gene id: 1616788:AR543_RS04545
uniprot id: A0A172ZCI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1616788:AR543 RS17720
gene id: 1616788:AR543_RS17720
uniprot id: A0A172ZJC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1616788:AR543 RS11065
gene id: 1616788:AR543_RS11065
uniprot id: A0A172ZFR7
names: Similarity
messages: Belongs to the peptidase S16 family.

1616788:AR543 RS09965
gene id: 1616788:AR543_RS09965
uniprot id: A0A172ZFK4
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS18270
gene id: 1616788:AR543_RS18270
uniprot id: A0A172ZJC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1616788:AR543 RS09130
gene id: 1616788:AR543_RS09130
uniprot id: A0A172ZG57
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1616788:AR543 RS11330
gene id: 1616788:AR543_RS11330
uniprot id: A0A172ZG87
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1616788:AR543 RS14960
gene id: 1616788:AR543_RS14960
uniprot id: A0A172ZHP3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS00265
gene id: 1616788:AR543_RS00265
uniprot id: A0A172ZBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1616788:AR543 RS06890
gene id: 1616788:AR543_RS06890
uniprot id: A0A172ZDY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS16320
gene id: 1616788:AR543_RS16320
uniprot id: A0A172ZID0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS06205
gene id: 1616788:AR543_RS06205
uniprot id: A0A172ZD94
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1616788:AR543 RS21415
gene id: 1616788:AR543_RS21415
uniprot id: A0A172ZL53
names: Subcellular Location Annotation
messages: cell wall

1616788:AR543 RS16455
gene id: 1616788:AR543_RS16455
uniprot id: A0A172ZJV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1616788:AR543 RS14930
gene id: 1616788:AR543_RS14930
uniprot id: A0A172ZHZ0
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS14580
gene id: 1616788:AR543_RS14580
uniprot id: A0A172ZNN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1616788:AR543 RS17850
gene id: 1616788:AR543_RS17850
uniprot id: A0A172ZJ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1616788:AR543 RS11765
gene id: 1616788:AR543_RS11765
uniprot id: A0A172ZG18
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS16965
gene id: 1616788:AR543_RS16965
uniprot id: A0A172ZIQ0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1616788:AR543 RS21735
gene id: 1616788:AR543_RS21735
uniprot id: A0A172ZL71
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1616788:AR543 RS05280
gene id: 1616788:AR543_RS05280
uniprot id: A0A172ZCU9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS20490
gene id: 1616788:AR543_RS20490
uniprot id: A0A172ZKQ1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1616788:AR543 RS03060
gene id: 1616788:AR543_RS03060
uniprot id: A0A172ZCM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1616788:AR543 RS02685
gene id: 1616788:AR543_RS02685
uniprot id: A0A172ZBL6
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1616788:AR543 RS19880
gene id: 1616788:AR543_RS19880
uniprot id: A0A172ZK76
names: Similarity
messages: Belongs to the RecJ family.

1616788:AR543 RS13425
gene id: 1616788:AR543_RS13425
uniprot id: A0A172ZHL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm

1616788:AR543 RS18600
gene id: 1616788:AR543_RS18600
uniprot id: A0A172ZJU5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS22245
gene id: 1616788:AR543_RS22245
uniprot id: A0A172ZLI8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1616788:AR543 RS22255
gene id: 1616788:AR543_RS22255
uniprot id: A0A172ZL84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1616788:AR543 RS07005
gene id: 1616788:AR543_RS07005
uniprot id: A0A172ZDM7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1616788:AR543 RS05695
gene id: 1616788:AR543_RS05695
uniprot id: A0A172ZE54
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1616788:AR543 RS15375
gene id: 1616788:AR543_RS15375
uniprot id: A0A172ZHW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1616788:AR543 RS08745
gene id: 1616788:AR543_RS08745
uniprot id: A0A172ZFA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS20105
gene id: 1616788:AR543_RS20105
uniprot id: A0A172ZK91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1616788:AR543 RS02485
gene id: 1616788:AR543_RS02485
uniprot id: A0A172ZBH7
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1616788:AR543 RS08825
gene id: 1616788:AR543_RS08825
uniprot id: A0A172ZFM9
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1616788:AR543 RS22190
gene id: 1616788:AR543_RS22190
uniprot id: A0A172ZLE0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1616788:AR543 RS09895
gene id: 1616788:AR543_RS09895
uniprot id: A0A172ZFG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1616788:AR543 RS03365
gene id: 1616788:AR543_RS03365
uniprot id: A0A172ZBY8
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

1616788:AR543 RS16680
gene id: 1616788:AR543_RS16680
uniprot id: A0A172ZJZ2
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

1616788:AR543 RS05145
gene id: 1616788:AR543_RS05145
uniprot id: A0A172ZD62
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS12615
gene id: 1616788:AR543_RS12615
uniprot id: A0A172ZGJ6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1616788:AR543 RS01750
gene id: 1616788:AR543_RS01750
uniprot id: A0A172ZC76
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1616788:AR543 RS20920
gene id: 1616788:AR543_RS20920
uniprot id: A0A172ZKP2
names: Similarity
messages: Belongs to the transpeptidase family.

1616788:AR543 RS11145
gene id: 1616788:AR543_RS11145
uniprot id: A0A172ZFR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1616788:AR543 RS08105
gene id: 1616788:AR543_RS08105
uniprot id: A0A172ZMC3
names: Similarity
messages: Belongs to the TPP enzyme family.

1616788:AR543 RS05035
gene id: 1616788:AR543_RS05035
uniprot id: A0A172ZCQ2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1616788:AR543 RS13035
gene id: 1616788:AR543_RS13035
uniprot id: A0A172ZGP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1616788:AR543 RS22135
gene id: 1616788:AR543_RS22135
uniprot id: A0A172ZMC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1616788:AR543 RS23380
gene id: 1616788:AR543_RS23380
uniprot id: A0A1X9T489
names: Similarity
messages: Belongs to the universal stress protein A family.

1616788:AR543 RS11730
gene id: 1616788:AR543_RS11730
uniprot id: A0A172ZG35
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1616788:AR543 RS14920
gene id: 1616788:AR543_RS14920
uniprot id: A0A172ZIN5
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS06480
gene id: 1616788:AR543_RS06480
uniprot id: A0A172ZM99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1616788:AR543 RS00735
gene id: 1616788:AR543_RS00735
uniprot id: A0A172ZB09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS18215
gene id: 1616788:AR543_RS18215
uniprot id: A0A172ZJL1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1616788:AR543 RS12655
gene id: 1616788:AR543_RS12655
uniprot id: A0A172ZH82
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1616788:AR543 RS03030
gene id: 1616788:AR543_RS03030
uniprot id: A0A172ZBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1616788:AR543 RS22910
gene id: 1616788:AR543_RS22910
uniprot id: A0A172ZMV3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1616788:AR543 RS03055
gene id: 1616788:AR543_RS03055
uniprot id: A0A172ZBU5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS01415
gene id: 1616788:AR543_RS01415
uniprot id: A0A172ZB23
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1616788:AR543 RS22365
gene id: 1616788:AR543_RS22365
uniprot id: A0A172ZLG5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

1616788:AR543 RS18010
gene id: 1616788:AR543_RS18010
uniprot id: A0A172ZJH2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS19940
gene id: 1616788:AR543_RS19940
uniprot id: A0A172ZKH8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1616788:AR543 RS11540
gene id: 1616788:AR543_RS11540
uniprot id: A0A172ZFZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1616788:AR543 RS08110
gene id: 1616788:AR543_RS08110
uniprot id: A0A172ZE83
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1616788:AR543 RS06235
gene id: 1616788:AR543_RS06235
uniprot id: A0A172ZD95
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS17145
gene id: 1616788:AR543_RS17145
uniprot id: A0A172ZIT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1616788:AR543 RS22955
gene id: 1616788:AR543_RS22955
uniprot id: A0A172ZLS4
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1616788:AR543 RS22230
gene id: 1616788:AR543_RS22230
uniprot id: A0A172ZL93
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1616788:AR543 RS17905
gene id: 1616788:AR543_RS17905
uniprot id: A0A172ZJ59
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS22185
gene id: 1616788:AR543_RS22185
uniprot id: A0A172ZME1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1616788:AR543 RS22560
gene id: 1616788:AR543_RS22560
uniprot id: A0A172ZLD4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1616788:AR543 RS14110
gene id: 1616788:AR543_RS14110
uniprot id: A0A172ZIQ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

1616788:AR543 RS20680
gene id: 1616788:AR543_RS20680
uniprot id: A0A172ZKT7
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1616788:AR543 RS17515
gene id: 1616788:AR543_RS17515
uniprot id: A0A172ZIZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1616788:AR543 RS22175
gene id: 1616788:AR543_RS22175
uniprot id: A0A172ZL68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1616788:AR543 RS18125
gene id: 1616788:AR543_RS18125
uniprot id: A0A172ZJ91
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1616788:AR543 RS14100
gene id: 1616788:AR543_RS14100
uniprot id: A0A172ZHK1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1616788:AR543 RS09935
gene id: 1616788:AR543_RS09935
uniprot id: A0A172ZG79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1616788:AR543 RS20480
gene id: 1616788:AR543_RS20480
uniprot id: A0A172ZKE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1616788:AR543 RS17510
gene id: 1616788:AR543_RS17510
uniprot id: A0A172ZIY7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1616788:AR543 RS10005
gene id: 1616788:AR543_RS10005
uniprot id: A0A172ZF64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1616788:AR543 RS09105
gene id: 1616788:AR543_RS09105
uniprot id: A0A172ZM48
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1616788:AR543 RS06060
gene id: 1616788:AR543_RS06060
uniprot id: A0A172ZE13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS11375
gene id: 1616788:AR543_RS11375
uniprot id: A0A172ZGL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1616788:AR543 RS09165
gene id: 1616788:AR543_RS09165
uniprot id: A0A172ZES0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS05840
gene id: 1616788:AR543_RS05840
uniprot id: A0A172ZD36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1616788:AR543 RS05605
gene id: 1616788:AR543_RS05605
uniprot id: A0A172ZLX3
names: Similarity
messages: Belongs to the EamA transporter family.

1616788:AR543 RS03155
gene id: 1616788:AR543_RS03155
uniprot id: A0A172ZC72
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1616788:AR543 RS16020
gene id: 1616788:AR543_RS16020
uniprot id: A0A172ZJN8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1616788:AR543 RS12340
gene id: 1616788:AR543_RS12340
uniprot id: A0A172ZGC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1616788:AR543 RS10110
gene id: 1616788:AR543_RS10110
uniprot id: A0A172ZGB0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1616788:AR543 RS00660
gene id: 1616788:AR543_RS00660
uniprot id: A0A172ZAM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

1616788:AR543 RS17960
gene id: 1616788:AR543_RS17960
uniprot id: A0A172ZJ67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1616788:AR543 RS13000
gene id: 1616788:AR543_RS13000
uniprot id: A0A172ZH11
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS08360
gene id: 1616788:AR543_RS08360
uniprot id: A0A172ZFF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1616788:AR543 RS13800
gene id: 1616788:AR543_RS13800
uniprot id: A0A172ZH44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1616788:AR543 RS22235
gene id: 1616788:AR543_RS22235
uniprot id: A0A172ZMF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1616788:AR543 RS00630
gene id: 1616788:AR543_RS00630
uniprot id: A0A172ZAY8
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS11270
gene id: 1616788:AR543_RS11270
uniprot id: A0A172ZFT5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1616788:AR543 RS19655
gene id: 1616788:AR543_RS19655
uniprot id: A0A172ZKC7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1616788:AR543 RS03585
gene id: 1616788:AR543_RS03585
uniprot id: A0A172ZCG4
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS21960
gene id: 1616788:AR543_RS21960
uniprot id: A0A172ZL26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1616788:AR543 RS19115
gene id: 1616788:AR543_RS19115
uniprot id: A0A172ZJT0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS02730
gene id: 1616788:AR543_RS02730
uniprot id: A0A172ZBN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1616788:AR543 RS14860
gene id: 1616788:AR543_RS14860
uniprot id: A0A172ZHY1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1616788:AR543 RS17995
gene id: 1616788:AR543_RS17995
uniprot id: A0A172ZJ82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1616788:AR543 RS03240
gene id: 1616788:AR543_RS03240
uniprot id: A0A172ZLS6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1616788:AR543 RS16815
gene id: 1616788:AR543_RS16815
uniprot id: A0A172ZIM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1616788:AR543 RS11570
gene id: 1616788:AR543_RS11570
uniprot id: A0A172ZFY6
names: Similarity
messages: Belongs to the peptidase M16 family.

1616788:AR543 RS09490
gene id: 1616788:AR543_RS09490
uniprot id: A0A172ZEW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1616788:AR543 RS20475
gene id: 1616788:AR543_RS20475
uniprot id: A0A172ZLW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS20875
gene id: 1616788:AR543_RS20875
uniprot id: A0A172ZKP7
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS21245
gene id: 1616788:AR543_RS21245
uniprot id: A0A172ZM92
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1616788:AR543 RS07685
gene id: 1616788:AR543_RS07685
uniprot id: A0A172ZE03
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1616788:AR543 RS18405
gene id: 1616788:AR543_RS18405
uniprot id: A0A172ZJJ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS00905
gene id: 1616788:AR543_RS00905
uniprot id: A0A172ZC34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS22530
gene id: 1616788:AR543_RS22530
uniprot id: A0A172ZLN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS11645
gene id: 1616788:AR543_RS11645
uniprot id: A0A172ZGR5
names: Similarity
messages: Belongs to the CinA family.

1616788:AR543 RS08425
gene id: 1616788:AR543_RS08425
uniprot id: A0A172ZEF9
names: Similarity
messages: Belongs to the peptidase S8 family.

1616788:AR543 RS08305
gene id: 1616788:AR543_RS08305
uniprot id: A0A172ZFE8
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS16740
gene id: 1616788:AR543_RS16740
uniprot id: A0A172ZK02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors.
messages: Membrane

1616788:AR543 RS17665
gene id: 1616788:AR543_RS17665
uniprot id: A0A172ZJQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1616788:AR543 RS03205
gene id: 1616788:AR543_RS03205
uniprot id: A0A172ZC81
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1616788:AR543 RS15115
gene id: 1616788:AR543_RS15115
uniprot id: A0A172ZMG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1616788:AR543 RS19660
gene id: 1616788:AR543_RS19660
uniprot id: A0A172ZK35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1616788:AR543 RS13490
gene id: 1616788:AR543_RS13490
uniprot id: A0A172ZGZ3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS18570
gene id: 1616788:AR543_RS18570
uniprot id: A0A172ZKL3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1616788:AR543 RS07555
gene id: 1616788:AR543_RS07555
uniprot id: A0A172ZNA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS09205
gene id: 1616788:AR543_RS09205
uniprot id: A0A172ZF69
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1616788:AR543 RS11295
gene id: 1616788:AR543_RS11295
uniprot id: A0A172ZFV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1616788:AR543 RS06690
gene id: 1616788:AR543_RS06690
uniprot id: A0A172ZEB3
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS14630
gene id: 1616788:AR543_RS14630
uniprot id: A0A172ZN03
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

1616788:AR543 RS22390
gene id: 1616788:AR543_RS22390
uniprot id: A0A172ZLL2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1616788:AR543 RS16065
gene id: 1616788:AR543_RS16065
uniprot id: A0A172ZJ92
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1616788:AR543 RS21810
gene id: 1616788:AR543_RS21810
uniprot id: A0A172ZMI4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1616788:AR543 RS06580
gene id: 1616788:AR543_RS06580
uniprot id: A0A172ZDE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1616788:AR543 RS00470
gene id: 1616788:AR543_RS00470
uniprot id: A0A172ZAY5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS01805
gene id: 1616788:AR543_RS01805
uniprot id: A0A172ZB61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

1616788:AR543 RS22040
gene id: 1616788:AR543_RS22040
uniprot id: A0A172ZML7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1616788:AR543 RS21980
gene id: 1616788:AR543_RS21980
uniprot id: A0A172ZLD8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1616788:AR543 RS09945
gene id: 1616788:AR543_RS09945
uniprot id: A0A172ZFH3
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1616788:AR543 RS03520
gene id: 1616788:AR543_RS03520
uniprot id: A0A172ZC18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1616788:AR543 RS05935
gene id: 1616788:AR543_RS05935
uniprot id: A0A172ZD49
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1616788:AR543 RS16780
gene id: 1616788:AR543_RS16780
uniprot id: A0A172ZIR4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1616788:AR543 RS20125
gene id: 1616788:AR543_RS20125
uniprot id: A0A172ZK95
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1616788:AR543 RS13175
gene id: 1616788:AR543_RS13175
uniprot id: A0A172ZGS5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS03610
gene id: 1616788:AR543_RS03610
uniprot id: A0A172ZC59
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1616788:AR543 RS22735
gene id: 1616788:AR543_RS22735
uniprot id: A0A172ZLS7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.

1616788:AR543 RS09355
gene id: 1616788:AR543_RS09355
uniprot id: A0A172ZGA3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS17900
gene id: 1616788:AR543_RS17900
uniprot id: A0A172ZJ57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1616788:AR543 RS19740
gene id: 1616788:AR543_RS19740
uniprot id: A0A172ZL80
names: Similarity
messages: Belongs to the UPF0473 family.

1616788:AR543 RS11855
gene id: 1616788:AR543_RS11855
uniprot id: A0A172ZH54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS19650
gene id: 1616788:AR543_RS19650
uniprot id: A0A172ZKQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

1616788:AR543 RS17785
gene id: 1616788:AR543_RS17785
uniprot id: A0A172ZJ37
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1616788:AR543 RS01865
gene id: 1616788:AR543_RS01865
uniprot id: A0A172ZC98
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1616788:AR543 RS05210
gene id: 1616788:AR543_RS05210
uniprot id: A0A172ZN41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS21705
gene id: 1616788:AR543_RS21705
uniprot id: A0A172ZLA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1616788:AR543 RS22510
gene id: 1616788:AR543_RS22510
uniprot id: A0A172ZLC5
names: Similarity
messages: Belongs to the peptidase S41A family.

1616788:AR543 RS18205
gene id: 1616788:AR543_RS18205
uniprot id: A0A172ZJC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1616788:AR543 RS22120
gene id: 1616788:AR543_RS22120
uniprot id: A0A172ZL65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1616788:AR543 RS18325
gene id: 1616788:AR543_RS18325
uniprot id: A0A172ZJD1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1616788:AR543 RS10805
gene id: 1616788:AR543_RS10805
uniprot id: A0A172ZMV4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS13265
gene id: 1616788:AR543_RS13265
uniprot id: A0A172ZGU8
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1616788:AR543 RS07310
gene id: 1616788:AR543_RS07310
uniprot id: A0A172ZM04
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1616788:AR543 RS15535
gene id: 1616788:AR543_RS15535
uniprot id: A0A172ZHY8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1616788:AR543 RS14845
gene id: 1616788:AR543_RS14845
uniprot id: A0A172ZHN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1616788:AR543 RS22585
gene id: 1616788:AR543_RS22585
uniprot id: A0A172ZMW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1616788:AR543 RS04695
gene id: 1616788:AR543_RS04695
uniprot id: A0A172ZCN3
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS12210
gene id: 1616788:AR543_RS12210
uniprot id: A0A172ZGA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

1616788:AR543 RS02910
gene id: 1616788:AR543_RS02910
uniprot id: A0A172ZBR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1616788:AR543 RS03135
gene id: 1616788:AR543_RS03135
uniprot id: A0A172ZBV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1616788:AR543 RS09145
gene id: 1616788:AR543_RS09145
uniprot id: A0A172ZFH7
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1616788:AR543 RS12735
gene id: 1616788:AR543_RS12735
uniprot id: A0A172ZGK1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS07760
gene id: 1616788:AR543_RS07760
uniprot id: A0A172ZEI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS22405
gene id: 1616788:AR543_RS22405
uniprot id: A0A172ZLC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1616788:AR543 RS03630
gene id: 1616788:AR543_RS03630
uniprot id: A0A172ZCX1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1616788:AR543 RS16685
gene id: 1616788:AR543_RS16685
uniprot id: A0A172ZIJ6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1616788:AR543 RS13565
gene id: 1616788:AR543_RS13565
uniprot id: A0A172ZH03
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1616788:AR543 RS13295
gene id: 1616788:AR543_RS13295
uniprot id: A0A172ZHJ1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1616788:AR543 RS07650
gene id: 1616788:AR543_RS07650
uniprot id: A0A172ZE02
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS18590
gene id: 1616788:AR543_RS18590
uniprot id: A0A172ZJJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1616788:AR543 RS12880
gene id: 1616788:AR543_RS12880
uniprot id: A0A172ZGZ4
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS01360
gene id: 1616788:AR543_RS01360
uniprot id: A0A172ZCC0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS01775
gene id: 1616788:AR543_RS01775
uniprot id: A0A172ZB63
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1616788:AR543 RS19790
gene id: 1616788:AR543_RS19790
uniprot id: A0A172ZK67
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1616788:AR543 RS18780
gene id: 1616788:AR543_RS18780
uniprot id: A0A172ZJL4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1616788:AR543 RS15920
gene id: 1616788:AR543_RS15920
uniprot id: A0A172ZI53
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

1616788:AR543 RS00585
gene id: 1616788:AR543_RS00585
uniprot id: A0A172ZLY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS13395
gene id: 1616788:AR543_RS13395
uniprot id: A0A172ZHW9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS22790
gene id: 1616788:AR543_RS22790
uniprot id: A0A172ZMZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1616788:AR543 RS14005
gene id: 1616788:AR543_RS14005
uniprot id: A0A172ZIN4
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1616788:AR543 RS16790
gene id: 1616788:AR543_RS16790
uniprot id: A0A172ZK12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Homodimer.
messages: Monomer.
messages: Secreted

1616788:AR543 RS10915
gene id: 1616788:AR543_RS10915
uniprot id: A0A172ZH32
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

1616788:AR543 RS20180
gene id: 1616788:AR543_RS20180
uniprot id: A0A172ZKA5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1616788:AR543 RS14820
gene id: 1616788:AR543_RS14820
uniprot id: A0A172ZIA7
names: Similarity
messages: Belongs to the Lgt family.

1616788:AR543 RS20075
gene id: 1616788:AR543_RS20075
uniprot id: A0A172ZK85
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1616788:AR543 RS10685
gene id: 1616788:AR543_RS10685
uniprot id: A0A172ZG98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1616788:AR543 RS18480
gene id: 1616788:AR543_RS18480
uniprot id: A0A172ZJR2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1616788:AR543 RS11650
gene id: 1616788:AR543_RS11650
uniprot id: A0A172ZGE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1616788:AR543 RS16060
gene id: 1616788:AR543_RS16060
uniprot id: A0A172ZI82
names: Similarity
messages: Belongs to the GbsR family.

1616788:AR543 RS08840
gene id: 1616788:AR543_RS08840
uniprot id: A0A172ZG05
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1616788:AR543 RS13735
gene id: 1616788:AR543_RS13735
uniprot id: A0A172ZHD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1616788:AR543 RS13280
gene id: 1616788:AR543_RS13280
uniprot id: A0A172ZH62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS15185
gene id: 1616788:AR543_RS15185
uniprot id: A0A172ZI40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1616788:AR543 RS22525
gene id: 1616788:AR543_RS22525
uniprot id: A0A172ZLJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1616788:AR543 RS05725
gene id: 1616788:AR543_RS05725
uniprot id: A0A172ZDH2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1616788:AR543 RS03565
gene id: 1616788:AR543_RS03565
uniprot id: A0A172ZDG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1616788:AR543 RS07515
gene id: 1616788:AR543_RS07515
uniprot id: A0A172ZFD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS09645
gene id: 1616788:AR543_RS09645
uniprot id: A0A172ZFE2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1616788:AR543 RS18000
gene id: 1616788:AR543_RS18000
uniprot id: A0A172ZJU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS06105
gene id: 1616788:AR543_RS06105
uniprot id: A0A172ZDK8
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1616788:AR543 RS17635
gene id: 1616788:AR543_RS17635
uniprot id: A0A172ZJ02
names: Similarity
messages: Belongs to the asp23 family.

1616788:AR543 RS08570
gene id: 1616788:AR543_RS08570
uniprot id: A0A172ZEG9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1616788:AR543 RS01070
gene id: 1616788:AR543_RS01070
uniprot id: A0A172ZC71
names: Similarity
messages: Belongs to the peptidase C15 family.

1616788:AR543 RS16085
gene id: 1616788:AR543_RS16085
uniprot id: A0A172ZI83
names: Similarity
messages: Belongs to the UPF0312 family.

1616788:AR543 RS09055
gene id: 1616788:AR543_RS09055
uniprot id: A0A172ZF19
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1616788:AR543 RS13635
gene id: 1616788:AR543_RS13635
uniprot id: A0A172ZHC4
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1616788:AR543 RS04265
gene id: 1616788:AR543_RS04265
uniprot id: A0A172ZCD3
names: Subcellular Location Annotation
messages: Cytoplasm

1616788:AR543 RS14280
gene id: 1616788:AR543_RS14280
uniprot id: A0A172ZMP3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS11760
gene id: 1616788:AR543_RS11760
uniprot id: A0A172ZMJ6
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS22015
gene id: 1616788:AR543_RS22015
uniprot id: A0A172ZL34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1616788:AR543 RS14680
gene id: 1616788:AR543_RS14680
uniprot id: A0A172ZHJ0
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS12795
gene id: 1616788:AR543_RS12795
uniprot id: A0A172ZGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS16080
gene id: 1616788:AR543_RS16080
uniprot id: A0A172ZJP8
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.

1616788:AR543 RS14215
gene id: 1616788:AR543_RS14215
uniprot id: A0A172ZHA9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS13160
gene id: 1616788:AR543_RS13160
uniprot id: A0A172ZMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS01310
gene id: 1616788:AR543_RS01310
uniprot id: A0A172ZCB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS14875
gene id: 1616788:AR543_RS14875
uniprot id: A0A172ZIB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1616788:AR543 RS21070
gene id: 1616788:AR543_RS21070
uniprot id: A0A172ZL15
names: Similarity
messages: Belongs to the PspA/IM30 family.

1616788:AR543 RS04760
gene id: 1616788:AR543_RS04760
uniprot id: A0A172ZCP6
names: Similarity
messages: Belongs to the universal stress protein A family.

1616788:AR543 RS22110
gene id: 1616788:AR543_RS22110
uniprot id: A0A172ZLV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1616788:AR543 RS05400
gene id: 1616788:AR543_RS05400
uniprot id: A0A172ZD03
names: Similarity
messages: Belongs to the Nth/MutY family.

1616788:AR543 RS21835
gene id: 1616788:AR543_RS21835
uniprot id: A0A172ZL25
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS19395
gene id: 1616788:AR543_RS19395
uniprot id: A0A172ZJX9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1616788:AR543 RS05390
gene id: 1616788:AR543_RS05390
uniprot id: A0A172ZCW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1616788:AR543 RS20285
gene id: 1616788:AR543_RS20285
uniprot id: A0A172ZKL9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS17795
gene id: 1616788:AR543_RS17795
uniprot id: A0A172ZK69
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1616788:AR543 RS14395
gene id: 1616788:AR543_RS14395
uniprot id: A0A172ZIE0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1616788:AR543 RS09575
gene id: 1616788:AR543_RS09575
uniprot id: A0A172ZEZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS04740
gene id: 1616788:AR543_RS04740
uniprot id: A0A172ZCL4
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1616788:AR543 RS20515
gene id: 1616788:AR543_RS20515
uniprot id: A0A172ZKK6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1616788:AR543 RS18305
gene id: 1616788:AR543_RS18305
uniprot id: A0A172ZKS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1616788:AR543 RS21250
gene id: 1616788:AR543_RS21250
uniprot id: A0A172ZKS2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1616788:AR543 RS14025
gene id: 1616788:AR543_RS14025
uniprot id: A0A172ZH78
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS08230
gene id: 1616788:AR543_RS08230
uniprot id: A0A172ZEA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1616788:AR543 RS03535
gene id: 1616788:AR543_RS03535
uniprot id: A0A172ZC13
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1616788:AR543 RS14115
gene id: 1616788:AR543_RS14115
uniprot id: A0A172ZH96
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1616788:AR543 RS05515
gene id: 1616788:AR543_RS05515
uniprot id: A0A172ZCY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

1616788:AR543 RS14260
gene id: 1616788:AR543_RS14260
uniprot id: A0A172ZHB8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1616788:AR543 RS06055
gene id: 1616788:AR543_RS06055
uniprot id: A0A172ZD63
names: Subcellular Location Annotation
messages: Cell membrane

1616788:AR543 RS06845
gene id: 1616788:AR543_RS06845
uniprot id: A0A172ZF06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS14335
gene id: 1616788:AR543_RS14335
uniprot id: A0A172ZHD2
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1616788:AR543 RS09910
gene id: 1616788:AR543_RS09910
uniprot id: A0A172ZFX0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1616788:AR543 RS08820
gene id: 1616788:AR543_RS08820
uniprot id: A0A172ZEL1
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1616788:AR543 RS03895
gene id: 1616788:AR543_RS03895
uniprot id: A0A172ZDB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS13670
gene id: 1616788:AR543_RS13670
uniprot id: A0A172ZHC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1616788:AR543 RS10170
gene id: 1616788:AR543_RS10170
uniprot id: A0A172ZFD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS16140
gene id: 1616788:AR543_RS16140
uniprot id: A0A172ZI93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1616788:AR543 RS18275
gene id: 1616788:AR543_RS18275
uniprot id: A0A172ZML4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1616788:AR543 RS10340
gene id: 1616788:AR543_RS10340
uniprot id: A0A172ZGU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS21390
gene id: 1616788:AR543_RS21390
uniprot id: A0A172ZKV8
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS09195
gene id: 1616788:AR543_RS09195
uniprot id: A0A172ZES1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1616788:AR543 RS00375
gene id: 1616788:AR543_RS00375
uniprot id: A0A172ZAI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the UbiD family. YclC subfamily.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives.

1616788:AR543 RS18395
gene id: 1616788:AR543_RS18395
uniprot id: A0A172ZJE7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1616788:AR543 RS00525
gene id: 1616788:AR543_RS00525
uniprot id: A0A172ZAK7
names: Similarity
messages: Belongs to the Dps family.

1616788:AR543 RS10530
gene id: 1616788:AR543_RS10530
uniprot id: A0A172ZFD8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1616788:AR543 RS20550
gene id: 1616788:AR543_RS20550
uniprot id: A0A172ZKG5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS20130
gene id: 1616788:AR543_RS20130
uniprot id: A0A172ZMP6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1616788:AR543 RS12150
gene id: 1616788:AR543_RS12150
uniprot id: A0A172ZGN4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1616788:AR543 RS15970
gene id: 1616788:AR543_RS15970
uniprot id: A0A172ZI63
names: Subunit
messages: Homodimer.

1616788:AR543 RS09930
gene id: 1616788:AR543_RS09930
uniprot id: A0A172ZF60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS17065
gene id: 1616788:AR543_RS17065
uniprot id: A0A172ZIP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1616788:AR543 RS03695
gene id: 1616788:AR543_RS03695
uniprot id: A0A172ZC43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1616788:AR543 RS12320
gene id: 1616788:AR543_RS12320
uniprot id: A0A172ZHS3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1616788:AR543 RS22500
gene id: 1616788:AR543_RS22500
uniprot id: A0A172ZLN2
names: Similarity
messages: Belongs to the MotB family.

1616788:AR543 RS19750
gene id: 1616788:AR543_RS19750
uniprot id: A0A172ZKE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1616788:AR543 RS19675
gene id: 1616788:AR543_RS19675
uniprot id: A0A172ZL70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1616788:AR543 RS01860
gene id: 1616788:AR543_RS01860
uniprot id: A0A172ZB76
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1616788:AR543 RS10630
gene id: 1616788:AR543_RS10630
uniprot id: A0A172ZFF6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS05890
gene id: 1616788:AR543_RS05890
uniprot id: A0A172ZD56
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1616788:AR543 RS22455
gene id: 1616788:AR543_RS22455
uniprot id: A0A172ZLC2
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS11350
gene id: 1616788:AR543_RS11350
uniprot id: A0A172ZGV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1616788:AR543 RS17095
gene id: 1616788:AR543_RS17095
uniprot id: A0A172ZJF8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1616788:AR543 RS07430
gene id: 1616788:AR543_RS07430
uniprot id: A0A172ZDW8
names: Similarity
messages: Belongs to the IF-3 family.

1616788:AR543 RS20765
gene id: 1616788:AR543_RS20765
uniprot id: A0A172ZKK3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS18465
gene id: 1616788:AR543_RS18465
uniprot id: A0A172ZKJ1
names: Similarity
messages: Belongs to the CvfB family.

1616788:AR543 RS12935
gene id: 1616788:AR543_RS12935
uniprot id: A0A172ZH02
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS17560
gene id: 1616788:AR543_RS17560
uniprot id: A0A172ZJN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1616788:AR543 RS17570
gene id: 1616788:AR543_RS17570
uniprot id: A0A172ZIZ7
names: Similarity
messages: Belongs to the RemA family.

1616788:AR543 RS05355
gene id: 1616788:AR543_RS05355
uniprot id: A0A172ZEB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS13755
gene id: 1616788:AR543_RS13755
uniprot id: A0A172ZI29
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1616788:AR543 RS13625
gene id: 1616788:AR543_RS13625
uniprot id: A0A172ZI09
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

1616788:AR543 RS18585
gene id: 1616788:AR543_RS18585
uniprot id: A0A172ZKY1
names: Similarity
messages: Belongs to the EamA transporter family.

1616788:AR543 RS12585
gene id: 1616788:AR543_RS12585
uniprot id: A0A172ZGG5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1616788:AR543 RS03755
gene id: 1616788:AR543_RS03755
uniprot id: A0A172ZC53
names: Similarity
messages: Belongs to the PspA/IM30 family.

1616788:AR543 RS14125
gene id: 1616788:AR543_RS14125
uniprot id: A0A172ZHK0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS19525
gene id: 1616788:AR543_RS19525
uniprot id: A0A172ZLF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1616788:AR543 RS00960
gene id: 1616788:AR543_RS00960
uniprot id: A0A172ZB46
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1616788:AR543 RS16285
gene id: 1616788:AR543_RS16285
uniprot id: A0A172ZJD5
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS20905
gene id: 1616788:AR543_RS20905
uniprot id: A0A172ZLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS01810
gene id: 1616788:AR543_RS01810
uniprot id: A0A172ZB68
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS15415
gene id: 1616788:AR543_RS15415
uniprot id: A0A172ZIK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1616788:AR543 RS06855
gene id: 1616788:AR543_RS06855
uniprot id: A0A172ZEE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1616788:AR543 RS03250
gene id: 1616788:AR543_RS03250
uniprot id: A0A172ZBW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1616788:AR543 RS16595
gene id: 1616788:AR543_RS16595
uniprot id: A0A172ZIH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1616788:AR543 RS22540
gene id: 1616788:AR543_RS22540
uniprot id: A0A172ZLD3
names: Similarity
messages: Belongs to the UxaA family.

1616788:AR543 RS19595
gene id: 1616788:AR543_RS19595
uniprot id: A0A172ZKB7
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1616788:AR543 RS08050
gene id: 1616788:AR543_RS08050
uniprot id: A0A172ZN12
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1616788:AR543 RS08380
gene id: 1616788:AR543_RS08380
uniprot id: A0A172ZEC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1616788:AR543 RS09220
gene id: 1616788:AR543_RS09220
uniprot id: A0A172ZET0
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS10380
gene id: 1616788:AR543_RS10380
uniprot id: A0A172ZFH4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1616788:AR543 RS11725
gene id: 1616788:AR543_RS11725
uniprot id: A0A172ZG23
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1616788:AR543 RS09995
gene id: 1616788:AR543_RS09995
uniprot id: A0A172ZFI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1616788:AR543 RS19295
gene id: 1616788:AR543_RS19295
uniprot id: A0A172ZKZ3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1616788:AR543 RS22460
gene id: 1616788:AR543_RS22460
uniprot id: A0A172ZLB3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1616788:AR543 RS04130
gene id: 1616788:AR543_RS04130
uniprot id: A0A172ZCM9
names: Similarity
messages: Belongs to the pyruvate kinase family.

1616788:AR543 RS02075
gene id: 1616788:AR543_RS02075
uniprot id: A0A172ZCD6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1616788:AR543 RS15785
gene id: 1616788:AR543_RS15785
uniprot id: A0A172ZIE3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1616788:AR543 RS11060
gene id: 1616788:AR543_RS11060
uniprot id: A0A172ZFN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1616788:AR543 RS19445
gene id: 1616788:AR543_RS19445
uniprot id: A0A172ZJY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1616788:AR543 RS21755
gene id: 1616788:AR543_RS21755
uniprot id: A0A172ZLQ2
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS09680
gene id: 1616788:AR543_RS09680
uniprot id: A0A172ZF36
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

1616788:AR543 RS10465
gene id: 1616788:AR543_RS10465
uniprot id: A0A172ZFU2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS11475
gene id: 1616788:AR543_RS11475
uniprot id: A0A172ZGN5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS09865
gene id: 1616788:AR543_RS09865
uniprot id: A0A172ZFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1616788:AR543 RS22240
gene id: 1616788:AR543_RS22240
uniprot id: A0A172ZLE9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1616788:AR543 RS11715
gene id: 1616788:AR543_RS11715
uniprot id: A0A172ZGF6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1616788:AR543 RS01380
gene id: 1616788:AR543_RS01380
uniprot id: A0A172ZLP7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS13445
gene id: 1616788:AR543_RS13445
uniprot id: A0A172ZGY1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS07580
gene id: 1616788:AR543_RS07580
uniprot id: A0A172ZDY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS01535
gene id: 1616788:AR543_RS01535
uniprot id: A0A172ZBD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS22850
gene id: 1616788:AR543_RS22850
uniprot id: A0A172ZLJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1616788:AR543 RS01450
gene id: 1616788:AR543_RS01450
uniprot id: A0A172ZB07
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS08000
gene id: 1616788:AR543_RS08000
uniprot id: A0A172ZE77
names: Similarity
messages: Belongs to the peptidase S8 family.

1616788:AR543 RS00445
gene id: 1616788:AR543_RS00445
uniprot id: A0A172ZAV9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1616788:AR543 RS22090
gene id: 1616788:AR543_RS22090
uniprot id: A0A172ZLC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1616788:AR543 RS18490
gene id: 1616788:AR543_RS18490
uniprot id: A0A172ZJH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1616788:AR543 RS07615
gene id: 1616788:AR543_RS07615
uniprot id: A0A172ZF17
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1616788:AR543 RS19250
gene id: 1616788:AR543_RS19250
uniprot id: A0A172ZJV0
names: Similarity
messages: Belongs to the threonine synthase family.

1616788:AR543 RS02350
gene id: 1616788:AR543_RS02350
uniprot id: A0A172ZBV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1616788:AR543 RS16445
gene id: 1616788:AR543_RS16445
uniprot id: A0A172ZIK2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1616788:AR543 RS19020
gene id: 1616788:AR543_RS19020
uniprot id: A0A172ZKU4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1616788:AR543 RS22465
gene id: 1616788:AR543_RS22465
uniprot id: A0A172ZLD5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1616788:AR543 RS17655
gene id: 1616788:AR543_RS17655
uniprot id: A0A172ZKG4
names: Similarity
messages: Belongs to the peptidase M29 family.

1616788:AR543 RS20650
gene id: 1616788:AR543_RS20650
uniprot id: A0A172ZKJ5
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1616788:AR543 RS18370
gene id: 1616788:AR543_RS18370
uniprot id: A0A172ZK21
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1616788:AR543 RS00785
gene id: 1616788:AR543_RS00785
uniprot id: A0A172ZBR6
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS17565
gene id: 1616788:AR543_RS17565
uniprot id: A0A172ZJ90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1616788:AR543 RS05880
gene id: 1616788:AR543_RS05880
uniprot id: A0A172ZDI7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1616788:AR543 RS07755
gene id: 1616788:AR543_RS07755
uniprot id: A0A172ZEU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS10660
gene id: 1616788:AR543_RS10660
uniprot id: A0A172ZGJ3
names: Similarity
messages: Belongs to the barstar family.

1616788:AR543 RS12440
gene id: 1616788:AR543_RS12440
uniprot id: A0A172ZGE3
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1616788:AR543 RS07395
gene id: 1616788:AR543_RS07395
uniprot id: A0A172ZFA9
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1616788:AR543 RS10140
gene id: 1616788:AR543_RS10140
uniprot id: A0A172ZG06
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1616788:AR543 RS22490
gene id: 1616788:AR543_RS22490
uniprot id: A0A172ZLC3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1616788:AR543 RS09375
gene id: 1616788:AR543_RS09375
uniprot id: A0A172ZF90
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1616788:AR543 RS00985
gene id: 1616788:AR543_RS00985
uniprot id: A0A172ZAT2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS05050
gene id: 1616788:AR543_RS05050
uniprot id: A0A172ZDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS22355
gene id: 1616788:AR543_RS22355
uniprot id: A0A172ZLB5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1616788:AR543 RS12000
gene id: 1616788:AR543_RS12000
uniprot id: A0A172ZG66
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS03675
gene id: 1616788:AR543_RS03675
uniprot id: A0A172ZDJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1616788:AR543 RS05070
gene id: 1616788:AR543_RS05070
uniprot id: A0A172ZD34
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1616788:AR543 RS17135
gene id: 1616788:AR543_RS17135
uniprot id: A0A172ZJ27
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

1616788:AR543 RS08460
gene id: 1616788:AR543_RS08460
uniprot id: A0A172ZMA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS11640
gene id: 1616788:AR543_RS11640
uniprot id: A0A172ZFZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1616788:AR543 RS04075
gene id: 1616788:AR543_RS04075
uniprot id: A0A172ZCA3
names: Cofactor
messages: Binds 1 FAD per subunit.

1616788:AR543 RS05540
gene id: 1616788:AR543_RS05540
uniprot id: A0A172ZDB4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1616788:AR543 RS11155
gene id: 1616788:AR543_RS11155
uniprot id: A0A172ZG59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1616788:AR543 RS11820
gene id: 1616788:AR543_RS11820
uniprot id: A0A172ZHI6
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1616788:AR543 RS02960
gene id: 1616788:AR543_RS02960
uniprot id: A0A172ZC57
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1616788:AR543 RS07220
gene id: 1616788:AR543_RS07220
uniprot id: A0A172ZDW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1616788:AR543 RS01730
gene id: 1616788:AR543_RS01730
uniprot id: A0A172ZBK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS11360
gene id: 1616788:AR543_RS11360
uniprot id: A0A172ZG65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1616788:AR543 RS16300
gene id: 1616788:AR543_RS16300
uniprot id: A0A172ZJT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1616788:AR543 RS09620
gene id: 1616788:AR543_RS09620
uniprot id: A0A172ZFB5
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS00575
gene id: 1616788:AR543_RS00575
uniprot id: A0A172ZLU5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1616788:AR543 RS19585
gene id: 1616788:AR543_RS19585
uniprot id: A0A172ZK08
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS10795
gene id: 1616788:AR543_RS10795
uniprot id: A0A172ZFK6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1616788:AR543 RS10215
gene id: 1616788:AR543_RS10215
uniprot id: A0A172ZFB6
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1616788:AR543 RS14510
gene id: 1616788:AR543_RS14510
uniprot id: A0A172ZIG1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS11215
gene id: 1616788:AR543_RS11215
uniprot id: A0A172ZGI7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1616788:AR543 RS19485
gene id: 1616788:AR543_RS19485
uniprot id: A0A172ZK98
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1616788:AR543 RS03305
gene id: 1616788:AR543_RS03305
uniprot id: A0A172ZMG9
names: Similarity
messages: Belongs to the peptidase C40 family.

1616788:AR543 RS16630
gene id: 1616788:AR543_RS16630
uniprot id: A0A172ZMT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1616788:AR543 RS15435
gene id: 1616788:AR543_RS15435
uniprot id: A0A172ZHY2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1616788:AR543 RS13025
gene id: 1616788:AR543_RS13025
uniprot id: A0A172ZML5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1616788:AR543 RS07400
gene id: 1616788:AR543_RS07400
uniprot id: A0A172ZDV5
names: Subcellular Location Annotation
messages: Cell membrane

1616788:AR543 RS20095
gene id: 1616788:AR543_RS20095
uniprot id: A0A172ZKJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1616788:AR543 RS12220
gene id: 1616788:AR543_RS12220
uniprot id: A0A172ZMH2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS17170
gene id: 1616788:AR543_RS17170
uniprot id: A0A172ZNE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1616788:AR543 RS12965
gene id: 1616788:AR543_RS12965
uniprot id: A0A172ZGN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

1616788:AR543 RS11885
gene id: 1616788:AR543_RS11885
uniprot id: A0A172ZGI6
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS13690
gene id: 1616788:AR543_RS13690
uniprot id: A0A172ZH19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1616788:AR543 RS18220
gene id: 1616788:AR543_RS18220
uniprot id: A0A172ZJB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1616788:AR543 RS17640
gene id: 1616788:AR543_RS17640
uniprot id: A0A172ZK40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1616788:AR543 RS14895
gene id: 1616788:AR543_RS14895
uniprot id: A0A172ZMG0
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1616788:AR543 RS02965
gene id: 1616788:AR543_RS02965
uniprot id: A0A172ZBR8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1616788:AR543 RS01185
gene id: 1616788:AR543_RS01185
uniprot id: A0A172ZB83
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1616788:AR543 RS01090
gene id: 1616788:AR543_RS01090
uniprot id: A0A172ZAV2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS05030
gene id: 1616788:AR543_RS05030
uniprot id: A0A172ZD43
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1616788:AR543 RS17175
gene id: 1616788:AR543_RS17175
uniprot id: A0A172ZIR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Catalyzes the conversion of pyruvate to formate and acetyl-CoA.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS01335
gene id: 1616788:AR543_RS01335
uniprot id: A0A172ZAY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS21865
gene id: 1616788:AR543_RS21865
uniprot id: A0A172ZMJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1616788:AR543 RS06775
gene id: 1616788:AR543_RS06775
uniprot id: A0A172ZDJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1616788:AR543 RS00535
gene id: 1616788:AR543_RS00535
uniprot id: A0A172ZAK9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS02750
gene id: 1616788:AR543_RS02750
uniprot id: A0A172ZBR5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1616788:AR543 RS16050
gene id: 1616788:AR543_RS16050
uniprot id: A0A172ZI77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS02305
gene id: 1616788:AR543_RS02305
uniprot id: A0A172ZBF2
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS07240
gene id: 1616788:AR543_RS07240
uniprot id: A0A172ZEL7
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1616788:AR543 RS04625
gene id: 1616788:AR543_RS04625
uniprot id: A0A172ZCJ4
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS11755
gene id: 1616788:AR543_RS11755
uniprot id: A0A172ZHH3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1616788:AR543 RS22310
gene id: 1616788:AR543_RS22310
uniprot id: A0A172ZL95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS10225
gene id: 1616788:AR543_RS10225
uniprot id: A0A172ZGC8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS14890
gene id: 1616788:AR543_RS14890
uniprot id: A0A172ZHN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1616788:AR543 RS11580
gene id: 1616788:AR543_RS11580
uniprot id: A0A172ZGD8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS22975
gene id: 1616788:AR543_RS22975
uniprot id: A0A172ZLL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS06440
gene id: 1616788:AR543_RS06440
uniprot id: A0A172ZDE6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1616788:AR543 RS21700
gene id: 1616788:AR543_RS21700
uniprot id: A0A172ZLP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1616788:AR543 RS06880
gene id: 1616788:AR543_RS06880
uniprot id: A0A172ZEP0
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS06270
gene id: 1616788:AR543_RS06270
uniprot id: A0A172ZED3
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1616788:AR543 RS22580
gene id: 1616788:AR543_RS22580
uniprot id: A0A172ZLP6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1616788:AR543 RS10635
gene id: 1616788:AR543_RS10635
uniprot id: A0A172ZFK1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS11180
gene id: 1616788:AR543_RS11180
uniprot id: A0A172ZGR6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1616788:AR543 RS20035
gene id: 1616788:AR543_RS20035
uniprot id: A0A172ZLB8
names: Similarity
messages: Belongs to the UPF0735 family.

1616788:AR543 RS01885
gene id: 1616788:AR543_RS01885
uniprot id: A0A172ZB81
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS02390
gene id: 1616788:AR543_RS02390
uniprot id: A0A172ZBT3
names: Similarity
messages: Belongs to the AHA1 family.

1616788:AR543 RS21210
gene id: 1616788:AR543_RS21210
uniprot id: A0A172ZKR6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1616788:AR543 RS15445
gene id: 1616788:AR543_RS15445
uniprot id: A0A172ZI26
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1616788:AR543 RS04735
gene id: 1616788:AR543_RS04735
uniprot id: A0A172ZCK7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS20080
gene id: 1616788:AR543_RS20080
uniprot id: A0A172ZKA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1616788:AR543 RS01940
gene id: 1616788:AR543_RS01940
uniprot id: A0A172ZB92
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1616788:AR543 RS20365
gene id: 1616788:AR543_RS20365
uniprot id: A0A172ZKN1
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS07985
gene id: 1616788:AR543_RS07985
uniprot id: A0A172ZEM1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1616788:AR543 RS08675
gene id: 1616788:AR543_RS08675
uniprot id: A0A172ZEV2
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1616788:AR543 RS17295
gene id: 1616788:AR543_RS17295
uniprot id: A0A172ZIZ9
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

1616788:AR543 RS14555
gene id: 1616788:AR543_RS14555
uniprot id: A0A172ZHH5
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS09940
gene id: 1616788:AR543_RS09940
uniprot id: A0A172ZF93
names: Similarity
messages: Belongs to the citrate synthase family.

1616788:AR543 RS21825
gene id: 1616788:AR543_RS21825
uniprot id: A0A172ZLC4
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS21330
gene id: 1616788:AR543_RS21330
uniprot id: A0A172ZKU9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1616788:AR543 RS08170
gene id: 1616788:AR543_RS08170
uniprot id: A0A172ZE94
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1616788:AR543 RS13245
gene id: 1616788:AR543_RS13245
uniprot id: A0A172ZN67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS13990
gene id: 1616788:AR543_RS13990
uniprot id: A0A172ZHC8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS03670
gene id: 1616788:AR543_RS03670
uniprot id: A0A172ZCG0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1616788:AR543 RS22360
gene id: 1616788:AR543_RS22360
uniprot id: A0A172ZMH0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1616788:AR543 RS19430
gene id: 1616788:AR543_RS19430
uniprot id: A0A172ZKL4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1616788:AR543 RS04360
gene id: 1616788:AR543_RS04360
uniprot id: A0A172ZCR7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1616788:AR543 RS19795
gene id: 1616788:AR543_RS19795
uniprot id: A0A172ZL90
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1616788:AR543 RS04955
gene id: 1616788:AR543_RS04955
uniprot id: A0A172ZE52
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1616788:AR543 RS02865
gene id: 1616788:AR543_RS02865
uniprot id: A0A172ZBT7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS05940
gene id: 1616788:AR543_RS05940
uniprot id: A0A172ZD66
names: Similarity
messages: Belongs to the GARS family.

1616788:AR543 RS17490
gene id: 1616788:AR543_RS17490
uniprot id: A0A172ZML1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1616788:AR543 RS19290
gene id: 1616788:AR543_RS19290
uniprot id: A0A172ZMU7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1616788:AR543 RS11785
gene id: 1616788:AR543_RS11785
uniprot id: A0A172ZMA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

1616788:AR543 RS06835
gene id: 1616788:AR543_RS06835
uniprot id: A0A172ZDQ0
names: Similarity
messages: Belongs to the GSP E family.

1616788:AR543 RS22395
gene id: 1616788:AR543_RS22395
uniprot id: A0A172ZLB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1616788:AR543 RS16395
gene id: 1616788:AR543_RS16395
uniprot id: A0A172ZIJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS08330
gene id: 1616788:AR543_RS08330
uniprot id: A0A172ZEC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1616788:AR543 RS15235
gene id: 1616788:AR543_RS15235
uniprot id: A0A172ZJA0
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1616788:AR543 RS05130
gene id: 1616788:AR543_RS05130
uniprot id: A0A172ZE80
names: Similarity
messages: Belongs to the CpsD/CapB family.

1616788:AR543 RS17330
gene id: 1616788:AR543_RS17330
uniprot id: A0A172ZIV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1616788:AR543 RS17290
gene id: 1616788:AR543_RS17290
uniprot id: A0A172ZJX2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS22980
gene id: 1616788:AR543_RS22980
uniprot id: A0A172ZMA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS16605
gene id: 1616788:AR543_RS16605
uniprot id: A0A172ZMR5
names: Similarity
messages: Belongs to the TrpF family.

1616788:AR543 RS18025
gene id: 1616788:AR543_RS18025
uniprot id: A0A172ZJ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1616788:AR543 RS11265
gene id: 1616788:AR543_RS11265
uniprot id: A0A172ZH92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1616788:AR543 RS16410
gene id: 1616788:AR543_RS16410
uniprot id: A0A172ZIE5
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

1616788:AR543 RS11685
gene id: 1616788:AR543_RS11685
uniprot id: A0A172ZG62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1616788:AR543 RS22860
gene id: 1616788:AR543_RS22860
uniprot id: A0A172ZLU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1616788:AR543 RS15925
gene id: 1616788:AR543_RS15925
uniprot id: A0A172ZIV1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1616788:AR543 RS11235
gene id: 1616788:AR543_RS11235
uniprot id: A0A172ZFU5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1616788:AR543 RS01815
gene id: 1616788:AR543_RS01815
uniprot id: A0A172ZC90
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS05020
gene id: 1616788:AR543_RS05020
uniprot id: A0A172ZDJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS05610
gene id: 1616788:AR543_RS05610
uniprot id: A0A172ZEE7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS17075
gene id: 1616788:AR543_RS17075
uniprot id: A0A172ZIW3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1616788:AR543 RS03540
gene id: 1616788:AR543_RS03540
uniprot id: A0A172ZC10
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1616788:AR543 RS22890
gene id: 1616788:AR543_RS22890
uniprot id: A0A172ZLV4
names: Similarity
messages: Belongs to the UPF0340 family.

1616788:AR543 RS19710
gene id: 1616788:AR543_RS19710
uniprot id: A0A172ZMP8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS17675
gene id: 1616788:AR543_RS17675
uniprot id: A0A172ZJ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1616788:AR543 RS16590
gene id: 1616788:AR543_RS16590
uniprot id: A0A172ZIH7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1616788:AR543 RS09950
gene id: 1616788:AR543_RS09950
uniprot id: A0A172ZGM8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1616788:AR543 RS17275
gene id: 1616788:AR543_RS17275
uniprot id: A0A172ZIU7
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1616788:AR543 RS05930
gene id: 1616788:AR543_RS05930
uniprot id: A0A172ZDJ5
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1616788:AR543 RS18045
gene id: 1616788:AR543_RS18045
uniprot id: A0A172ZKN0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1616788:AR543 RS18175
gene id: 1616788:AR543_RS18175
uniprot id: A0A172ZJA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1616788:AR543 RS00510
gene id: 1616788:AR543_RS00510
uniprot id: A0A172ZAK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS19945
gene id: 1616788:AR543_RS19945
uniprot id: A0A172ZNX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1616788:AR543 RS04755
gene id: 1616788:AR543_RS04755
uniprot id: A0A172ZDP9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS07765
gene id: 1616788:AR543_RS07765
uniprot id: A0A172ZE20
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

1616788:AR543 RS09010
gene id: 1616788:AR543_RS09010
uniprot id: A0A172ZFG1
names: Similarity
messages: Belongs to the thioesterase family.

1616788:AR543 RS10220
gene id: 1616788:AR543_RS10220
uniprot id: A0A172ZFB4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1616788:AR543 RS10390
gene id: 1616788:AR543_RS10390
uniprot id: A0A172ZGV2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1616788:AR543 RS07350
gene id: 1616788:AR543_RS07350
uniprot id: A0A172ZDT9
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

1616788:AR543 RS21990
gene id: 1616788:AR543_RS21990
uniprot id: A0A172ZL41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1616788:AR543 RS08490
gene id: 1616788:AR543_RS08490
uniprot id: A0A172ZFI2
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1616788:AR543 RS03050
gene id: 1616788:AR543_RS03050
uniprot id: A0A172ZD76
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1616788:AR543 RS16380
gene id: 1616788:AR543_RS16380
uniprot id: A0A172ZID6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1616788:AR543 RS03290
gene id: 1616788:AR543_RS03290
uniprot id: A0A172ZBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1616788:AR543 RS01340
gene id: 1616788:AR543_RS01340
uniprot id: A0A172ZAZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1616788:AR543 RS00730
gene id: 1616788:AR543_RS00730
uniprot id: A0A172ZAQ5
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS08340
gene id: 1616788:AR543_RS08340
uniprot id: A0A172ZES4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1616788:AR543 RS20050
gene id: 1616788:AR543_RS20050
uniprot id: A0A172ZLN8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1616788:AR543 RS08790
gene id: 1616788:AR543_RS08790
uniprot id: A0A172ZFZ4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS02715
gene id: 1616788:AR543_RS02715
uniprot id: A0A172ZBN0
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS00825
gene id: 1616788:AR543_RS00825
uniprot id: A0A172ZAQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS12475
gene id: 1616788:AR543_RS12475
uniprot id: A0A172ZGE9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1616788:AR543 RS04605
gene id: 1616788:AR543_RS04605
uniprot id: A0A172ZCX9
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1616788:AR543 RS19260
gene id: 1616788:AR543_RS19260
uniprot id: A0A172ZK58
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1616788:AR543 RS20145
gene id: 1616788:AR543_RS20145
uniprot id: A0A172ZKE4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1616788:AR543 RS09685
gene id: 1616788:AR543_RS09685
uniprot id: A0A172ZFC6
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1616788:AR543 RS17750
gene id: 1616788:AR543_RS17750
uniprot id: A0A172ZJD2
names: Similarity
messages: Belongs to the UPF0637 family.

1616788:AR543 RS11195
gene id: 1616788:AR543_RS11195
uniprot id: A0A172ZG34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1616788:AR543 RS11135
gene id: 1616788:AR543_RS11135
uniprot id: A0A172ZG22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1616788:AR543 RS08975
gene id: 1616788:AR543_RS08975
uniprot id: A0A172ZEN5
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS15120
gene id: 1616788:AR543_RS15120
uniprot id: A0A172ZHR9
names: Similarity
messages: Belongs to the PspA/IM30 family.

1616788:AR543 RS15635
gene id: 1616788:AR543_RS15635
uniprot id: A0A172ZJG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS04645
gene id: 1616788:AR543_RS04645
uniprot id: A0A172ZCW3
names: Similarity
messages: Belongs to the UPF0045 family.

1616788:AR543 RS01690
gene id: 1616788:AR543_RS01690
uniprot id: A0A172ZC66
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1616788:AR543 RS03655
gene id: 1616788:AR543_RS03655
uniprot id: A0A172ZD79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1616788:AR543 RS17990
gene id: 1616788:AR543_RS17990
uniprot id: A0A172ZKM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS20385
gene id: 1616788:AR543_RS20385
uniprot id: A0A172ZKD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1616788:AR543 RS21950
gene id: 1616788:AR543_RS21950
uniprot id: A0A172ZLD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1616788:AR543 RS20085
gene id: 1616788:AR543_RS20085
uniprot id: A0A172ZLD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1616788:AR543 RS08255
gene id: 1616788:AR543_RS08255
uniprot id: A0A172ZED4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS14595
gene id: 1616788:AR543_RS14595
uniprot id: A0A172ZHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1616788:AR543 RS04680
gene id: 1616788:AR543_RS04680
uniprot id: A0A172ZCK4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1616788:AR543 RS22025
gene id: 1616788:AR543_RS22025
uniprot id: A0A172ZMA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1616788:AR543 RS12855
gene id: 1616788:AR543_RS12855
uniprot id: A0A172ZGM0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1616788:AR543 RS03920
gene id: 1616788:AR543_RS03920
uniprot id: A0A172ZD22
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

1616788:AR543 RS11010
gene id: 1616788:AR543_RS11010
uniprot id: A0A172ZFQ6
names: Similarity
messages: Belongs to the SMP-30/CGR1 family.

1616788:AR543 RS09770
gene id: 1616788:AR543_RS09770
uniprot id: A0A172ZF14
names: Similarity
messages: Belongs to the Dps family.

1616788:AR543 RS10345
gene id: 1616788:AR543_RS10345
uniprot id: A0A172ZFC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS07835
gene id: 1616788:AR543_RS07835
uniprot id: A0A172ZE49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS20280
gene id: 1616788:AR543_RS20280
uniprot id: A0A172ZKG6
names: Similarity
messages: Belongs to the isochorismate synthase family.

1616788:AR543 RS11465
gene id: 1616788:AR543_RS11465
uniprot id: A0A172ZHD1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1616788:AR543 RS19920
gene id: 1616788:AR543_RS19920
uniprot id: A0A172ZK70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1616788:AR543 RS09230
gene id: 1616788:AR543_RS09230
uniprot id: A0A172ZEV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1616788:AR543 RS16360
gene id: 1616788:AR543_RS16360
uniprot id: A0A172ZID4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1616788:AR543 RS11355
gene id: 1616788:AR543_RS11355
uniprot id: A0A172ZFZ9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1616788:AR543 RS00125
gene id: 1616788:AR543_RS00125
uniprot id: A0A172ZAD8
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS09225
gene id: 1616788:AR543_RS09225
uniprot id: A0A172ZFV1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1616788:AR543 RS04160
gene id: 1616788:AR543_RS04160
uniprot id: A0A172ZCB3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1616788:AR543 RS18435
gene id: 1616788:AR543_RS18435
uniprot id: A0A172ZJQ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS08685
gene id: 1616788:AR543_RS08685
uniprot id: A0A172ZEH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS19615
gene id: 1616788:AR543_RS19615
uniprot id: A0A172ZL60
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1616788:AR543 RS17760
gene id: 1616788:AR543_RS17760
uniprot id: A0A172ZKI6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1616788:AR543 RS02780
gene id: 1616788:AR543_RS02780
uniprot id: A0A172ZBP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1616788:AR543 RS09000
gene id: 1616788:AR543_RS09000
uniprot id: A0A172ZG37
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS21785
gene id: 1616788:AR543_RS21785
uniprot id: A0A172ZM75
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS13550
gene id: 1616788:AR543_RS13550
uniprot id: A0A172ZHA5
names: Similarity
messages: Belongs to the peptidase M29 family.

1616788:AR543 RS02355
gene id: 1616788:AR543_RS02355
uniprot id: A0A172ZBF9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS15245
gene id: 1616788:AR543_RS15245
uniprot id: A0A172ZII4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1616788:AR543 RS02640
gene id: 1616788:AR543_RS02640
uniprot id: A0A172ZBL3
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1616788:AR543 RS12095
gene id: 1616788:AR543_RS12095
uniprot id: A0A172ZGM4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS13710
gene id: 1616788:AR543_RS13710
uniprot id: A0A172ZH74
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS01025
gene id: 1616788:AR543_RS01025
uniprot id: A0A172ZAT9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1616788:AR543 RS09405
gene id: 1616788:AR543_RS09405
uniprot id: A0A172ZEX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

1616788:AR543 RS03805
gene id: 1616788:AR543_RS03805
uniprot id: A0A172ZCJ7
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

1616788:AR543 RS11095
gene id: 1616788:AR543_RS11095
uniprot id: A0A172ZFQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1616788:AR543 RS04890
gene id: 1616788:AR543_RS04890
uniprot id: A0A172ZCR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1616788:AR543 RS17070
gene id: 1616788:AR543_RS17070
uniprot id: A0A172ZJS0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS16705
gene id: 1616788:AR543_RS16705
uniprot id: A0A172ZIU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1616788:AR543 RS19545
gene id: 1616788:AR543_RS19545
uniprot id: A0A172ZK17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1616788:AR543 RS21985
gene id: 1616788:AR543_RS21985
uniprot id: A0A172ZMK5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1616788:AR543 RS03705
gene id: 1616788:AR543_RS03705
uniprot id: A0A172ZC46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1616788:AR543 RS16450
gene id: 1616788:AR543_RS16450
uniprot id: A0A172ZIR0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1616788:AR543 RS19470
gene id: 1616788:AR543_RS19470
uniprot id: A0A172ZLE7
names: Similarity
messages: Belongs to the peptidase S9C family.

1616788:AR543 RS19420
gene id: 1616788:AR543_RS19420
uniprot id: A0A172ZLD7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS22615
gene id: 1616788:AR543_RS22615
uniprot id: A0A172ZLG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1616788:AR543 RS22080
gene id: 1616788:AR543_RS22080
uniprot id: A0A172ZL67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1616788:AR543 RS21240
gene id: 1616788:AR543_RS21240
uniprot id: A0A172ZL23
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1616788:AR543 RS08970
gene id: 1616788:AR543_RS08970
uniprot id: A0A172ZEM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1616788:AR543 RS19240
gene id: 1616788:AR543_RS19240
uniprot id: A0A172ZK54
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1616788:AR543 RS07930
gene id: 1616788:AR543_RS07930
uniprot id: A0A172ZEX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS09765
gene id: 1616788:AR543_RS09765
uniprot id: A0A172ZFG0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1616788:AR543 RS09550
gene id: 1616788:AR543_RS09550
uniprot id: A0A172ZEZ0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1616788:AR543 RS15165
gene id: 1616788:AR543_RS15165
uniprot id: A0A172ZI37
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS01825
gene id: 1616788:AR543_RS01825
uniprot id: A0A172ZBJ1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1616788:AR543 RS08310
gene id: 1616788:AR543_RS08310
uniprot id: A0A172ZEE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1616788:AR543 RS20200
gene id: 1616788:AR543_RS20200
uniprot id: A0A172ZKL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1616788:AR543 RS21060
gene id: 1616788:AR543_RS21060
uniprot id: A0A172ZLW3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1616788:AR543 RS19775
gene id: 1616788:AR543_RS19775
uniprot id: A0A172ZKE8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS04210
gene id: 1616788:AR543_RS04210
uniprot id: A0A172ZCQ5
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS16210
gene id: 1616788:AR543_RS16210
uniprot id: A0A172ZIA4
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1616788:AR543 RS05485
gene id: 1616788:AR543_RS05485
uniprot id: A0A172ZDA3
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS22325
gene id: 1616788:AR543_RS22325
uniprot id: A0A172ZLA3
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS06610
gene id: 1616788:AR543_RS06610
uniprot id: A0A172ZDG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS14520
gene id: 1616788:AR543_RS14520
uniprot id: A0A172ZHR8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS21560
gene id: 1616788:AR543_RS21560
uniprot id: A0A172ZM36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1616788:AR543 RS14945
gene id: 1616788:AR543_RS14945
uniprot id: A0A172ZIC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1616788:AR543 RS22670
gene id: 1616788:AR543_RS22670
uniprot id: A0A172ZLH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1616788:AR543 RS16835
gene id: 1616788:AR543_RS16835
uniprot id: A0A172ZJN7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1616788:AR543 RS22855
gene id: 1616788:AR543_RS22855
uniprot id: A0A172ZM87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1616788:AR543 RS16465
gene id: 1616788:AR543_RS16465
uniprot id: A0A172ZJ49
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1616788:AR543 RS02175
gene id: 1616788:AR543_RS02175
uniprot id: A0A172ZBD3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1616788:AR543 RS05315
gene id: 1616788:AR543_RS05315
uniprot id: A0A172ZD91
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1616788:AR543 RS14765
gene id: 1616788:AR543_RS14765
uniprot id: A0A172ZHK2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1616788:AR543 RS13410
gene id: 1616788:AR543_RS13410
uniprot id: A0A172ZMM3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS02535
gene id: 1616788:AR543_RS02535
uniprot id: A0A172ZBI7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS22485
gene id: 1616788:AR543_RS22485
uniprot id: A0A172ZMV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1616788:AR543 RS09500
gene id: 1616788:AR543_RS09500
uniprot id: A0A172ZEY1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1616788:AR543 RS11515
gene id: 1616788:AR543_RS11515
uniprot id: A0A172ZHE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1616788:AR543 RS03025
gene id: 1616788:AR543_RS03025
uniprot id: A0A172ZM26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1616788:AR543 RS02845
gene id: 1616788:AR543_RS02845
uniprot id: A0A172ZBP9
names: Similarity
messages: Belongs to the ParB family.

1616788:AR543 RS03685
gene id: 1616788:AR543_RS03685
uniprot id: A0A172ZCY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1616788:AR543 RS08940
gene id: 1616788:AR543_RS08940
uniprot id: A0A172ZEZ9
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS06770
gene id: 1616788:AR543_RS06770
uniprot id: A0A172ZDK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS15075
gene id: 1616788:AR543_RS15075
uniprot id: A0A172ZHQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homodimer.
messages: Secreted

1616788:AR543 RS20865
gene id: 1616788:AR543_RS20865
uniprot id: A0A172ZKN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS16370
gene id: 1616788:AR543_RS16370
uniprot id: A0A172ZIN6
names: Similarity
messages: Belongs to the RuBisCO large chain family.

1616788:AR543 RS00550
gene id: 1616788:AR543_RS00550
uniprot id: A0A172ZAX6
names: Subunit
messages: Homodimer.

1616788:AR543 RS00065
gene id: 1616788:AR543_RS00065
uniprot id: A0A172ZAC4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1616788:AR543 RS05025
gene id: 1616788:AR543_RS05025
uniprot id: A0A172ZLV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS10420
gene id: 1616788:AR543_RS10420
uniprot id: A0A172ZFB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS10830
gene id: 1616788:AR543_RS10830
uniprot id: A0A172ZFL8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1616788:AR543 RS18245
gene id: 1616788:AR543_RS18245
uniprot id: A0A172ZJM3
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS17530
gene id: 1616788:AR543_RS17530
uniprot id: A0A172ZJ36
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1616788:AR543 RS07730
gene id: 1616788:AR543_RS07730
uniprot id: A0A172ZE44
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS05305
gene id: 1616788:AR543_RS05305
uniprot id: A0A172ZCU7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1616788:AR543 RS13235
gene id: 1616788:AR543_RS13235
uniprot id: A0A172ZHI1
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1616788:AR543 RS02925
gene id: 1616788:AR543_RS02925
uniprot id: A0A172ZC30
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1616788:AR543 RS15730
gene id: 1616788:AR543_RS15730
uniprot id: A0A172ZI75
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1616788:AR543 RS17110
gene id: 1616788:AR543_RS17110
uniprot id: A0A172ZIR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1616788:AR543 RS19670
gene id: 1616788:AR543_RS19670
uniprot id: A0A172ZK47
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1616788:AR543 RS16610
gene id: 1616788:AR543_RS16610
uniprot id: A0A172ZIN2
names: Similarity
messages: Belongs to the TrpC family.

1616788:AR543 RS08060
gene id: 1616788:AR543_RS08060
uniprot id: A0A172ZE85
names: Similarity
messages: Belongs to the barstar family.

1616788:AR543 RS23000
gene id: 1616788:AR543_RS23000
uniprot id: A0A172ZAD5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1616788:AR543 RS02870
gene id: 1616788:AR543_RS02870
uniprot id: A0A172ZC20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

1616788:AR543 RS22555
gene id: 1616788:AR543_RS22555
uniprot id: A0A172ZLE2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS20415
gene id: 1616788:AR543_RS20415
uniprot id: A0A172ZKD9
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1616788:AR543 RS07245
gene id: 1616788:AR543_RS07245
uniprot id: A0A172ZE82
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1616788:AR543 RS11740
gene id: 1616788:AR543_RS11740
uniprot id: A0A172ZMW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1616788:AR543 RS09465
gene id: 1616788:AR543_RS09465
uniprot id: A0A172ZF88
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.
messages: Membrane

1616788:AR543 RS21345
gene id: 1616788:AR543_RS21345
uniprot id: A0A172ZL43
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS15135
gene id: 1616788:AR543_RS15135
uniprot id: A0A172ZHS2
names: Subcellular Location Annotation
messages: Cell membrane

1616788:AR543 RS03590
gene id: 1616788:AR543_RS03590
uniprot id: A0A172ZC22
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1616788:AR543 RS02805
gene id: 1616788:AR543_RS02805
uniprot id: A0A172ZBS6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1616788:AR543 RS05755
gene id: 1616788:AR543_RS05755
uniprot id: A0A172ZDG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS03150
gene id: 1616788:AR543_RS03150
uniprot id: A0A172ZBY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS07655
gene id: 1616788:AR543_RS07655
uniprot id: A0A172ZE11
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1616788:AR543 RS22695
gene id: 1616788:AR543_RS22695
uniprot id: A0A172ZLG4
names: Similarity
messages: Belongs to the bacterial flagellin family.

1616788:AR543 RS04865
gene id: 1616788:AR543_RS04865
uniprot id: A0A172ZD13
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1616788:AR543 RS21615
gene id: 1616788:AR543_RS21615
uniprot id: A0A172ZM46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS11385
gene id: 1616788:AR543_RS11385
uniprot id: A0A172ZFU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1616788:AR543 RS03680
gene id: 1616788:AR543_RS03680
uniprot id: A0A172ZC44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1616788:AR543 RS11275
gene id: 1616788:AR543_RS11275
uniprot id: A0A172ZGJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1616788:AR543 RS13285
gene id: 1616788:AR543_RS13285
uniprot id: A0A172ZIA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS02040
gene id: 1616788:AR543_RS02040
uniprot id: A0A172ZBA9
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS20410
gene id: 1616788:AR543_RS20410
uniprot id: A0A172ZLV2
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1616788:AR543 RS05310
gene id: 1616788:AR543_RS05310
uniprot id: A0A172ZDP5
names: Subcellular Location Annotation
messages: cell wall

1616788:AR543 RS20855
gene id: 1616788:AR543_RS20855
uniprot id: A0A172ZLB9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1616788:AR543 RS03210
gene id: 1616788:AR543_RS03210
uniprot id: A0A172ZDA9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS07845
gene id: 1616788:AR543_RS07845
uniprot id: A0A172ZF58
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1616788:AR543 RS11470
gene id: 1616788:AR543_RS11470
uniprot id: A0A172ZFW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1616788:AR543 RS11400
gene id: 1616788:AR543_RS11400
uniprot id: A0A172ZGW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1616788:AR543 RS17180
gene id: 1616788:AR543_RS17180
uniprot id: A0A172ZJV3
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1616788:AR543 RS11245
gene id: 1616788:AR543_RS11245
uniprot id: A0A172ZGT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1616788:AR543 RS09235
gene id: 1616788:AR543_RS09235
uniprot id: A0A172ZF53
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS21045
gene id: 1616788:AR543_RS21045
uniprot id: A0A172ZKR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1616788:AR543 RS11505
gene id: 1616788:AR543_RS11505
uniprot id: A0A172ZG29
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS21740
gene id: 1616788:AR543_RS21740
uniprot id: A0A172ZLB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1616788:AR543 RS15085
gene id: 1616788:AR543_RS15085
uniprot id: A0A172ZHS5
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS02900
gene id: 1616788:AR543_RS02900
uniprot id: A0A172ZBQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1616788:AR543 RS01635
gene id: 1616788:AR543_RS01635
uniprot id: A0A172ZC58
names: Similarity
messages: Belongs to the EamA transporter family.

1616788:AR543 RS19435
gene id: 1616788:AR543_RS19435
uniprot id: A0A172ZK88
names: Similarity
messages: Belongs to the manganese catalase family.

1616788:AR543 RS06080
gene id: 1616788:AR543_RS06080
uniprot id: A0A172ZD88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1616788:AR543 RS18255
gene id: 1616788:AR543_RS18255
uniprot id: A0A172ZJD7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1616788:AR543 RS04620
gene id: 1616788:AR543_RS04620
uniprot id: A0A172ZCI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS19645
gene id: 1616788:AR543_RS19645
uniprot id: A0A172ZK19
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1616788:AR543 RS20600
gene id: 1616788:AR543_RS20600
uniprot id: A0A172ZKH2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1616788:AR543 RS00460
gene id: 1616788:AR543_RS00460
uniprot id: A0A172ZAJ1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1616788:AR543 RS22665
gene id: 1616788:AR543_RS22665
uniprot id: A0A172ZLF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1616788:AR543 RS19380
gene id: 1616788:AR543_RS19380
uniprot id: A0A172ZKK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1616788:AR543 RS16230
gene id: 1616788:AR543_RS16230
uniprot id: A0A172ZIG3
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS14195
gene id: 1616788:AR543_RS14195
uniprot id: A0A172ZHZ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1616788:AR543 RS11315
gene id: 1616788:AR543_RS11315
uniprot id: A0A172ZHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS16820
gene id: 1616788:AR543_RS16820
uniprot id: A0A172ZIM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1616788:AR543 RS00620
gene id: 1616788:AR543_RS00620
uniprot id: A0A172ZMC8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS00480
gene id: 1616788:AR543_RS00480
uniprot id: A0A172ZAJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1616788:AR543 RS22575
gene id: 1616788:AR543_RS22575
uniprot id: A0A172ZLK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

1616788:AR543 RS19270
gene id: 1616788:AR543_RS19270
uniprot id: A0A172ZJW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1616788:AR543 RS21595
gene id: 1616788:AR543_RS21595
uniprot id: A0A172ZL85
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1616788:AR543 RS15200
gene id: 1616788:AR543_RS15200
uniprot id: A0A172ZHT8
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS05875
gene id: 1616788:AR543_RS05875
uniprot id: A0A172ZDY0
names: Similarity
messages: Belongs to the universal stress protein A family.

1616788:AR543 RS18200
gene id: 1616788:AR543_RS18200
uniprot id: A0A172ZKQ9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1616788:AR543 RS08670
gene id: 1616788:AR543_RS08670
uniprot id: A0A172ZEJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1616788:AR543 RS02365
gene id: 1616788:AR543_RS02365
uniprot id: A0A172ZBG4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1616788:AR543 RS18950
gene id: 1616788:AR543_RS18950
uniprot id: A0A172ZJZ6
names: Subunit
messages: Homodimer.

1616788:AR543 RS14725
gene id: 1616788:AR543_RS14725
uniprot id: A0A172ZHJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1616788:AR543 RS17285
gene id: 1616788:AR543_RS17285
uniprot id: A0A172ZIT7
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1616788:AR543 RS08615
gene id: 1616788:AR543_RS08615
uniprot id: A0A172ZF89
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS22590
gene id: 1616788:AR543_RS22590
uniprot id: A0A172ZLE3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1616788:AR543 RS06990
gene id: 1616788:AR543_RS06990
uniprot id: A0A172ZDS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS18095
gene id: 1616788:AR543_RS18095
uniprot id: A0A172ZKP0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1616788:AR543 RS13795
gene id: 1616788:AR543_RS13795
uniprot id: A0A172ZH38
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

1616788:AR543 RS18320
gene id: 1616788:AR543_RS18320
uniprot id: A0A172ZJN1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1616788:AR543 RS00310
gene id: 1616788:AR543_RS00310
uniprot id: A0A172ZAH2
names: Similarity
messages: Belongs to the TelA family.

1616788:AR543 RS14015
gene id: 1616788:AR543_RS14015
uniprot id: A0A172ZHW4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1616788:AR543 RS22195
gene id: 1616788:AR543_RS22195
uniprot id: A0A172ZLH8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1616788:AR543 RS08405
gene id: 1616788:AR543_RS08405
uniprot id: A0A172ZEF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS02850
gene id: 1616788:AR543_RS02850
uniprot id: A0A172ZBP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

1616788:AR543 RS09315
gene id: 1616788:AR543_RS09315
uniprot id: A0A172ZFK9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1616788:AR543 RS03000
gene id: 1616788:AR543_RS03000
uniprot id: A0A172ZBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1616788:AR543 RS20140
gene id: 1616788:AR543_RS20140
uniprot id: A0A172ZLE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1616788:AR543 RS15460
gene id: 1616788:AR543_RS15460
uniprot id: A0A172ZN08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS01955
gene id: 1616788:AR543_RS01955
uniprot id: A0A172ZB94
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

1616788:AR543 RS00225
gene id: 1616788:AR543_RS00225
uniprot id: A0A172ZBS0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1616788:AR543 RS22805
gene id: 1616788:AR543_RS22805
uniprot id: A0A172ZM79
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1616788:AR543 RS06680
gene id: 1616788:AR543_RS06680
uniprot id: A0A172ZEX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS15490
gene id: 1616788:AR543_RS15490
uniprot id: A0A172ZHZ2
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1616788:AR543 RS09035
gene id: 1616788:AR543_RS09035
uniprot id: A0A172ZEP5
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1616788:AR543 RS17085
gene id: 1616788:AR543_RS17085
uniprot id: A0A172ZK63
names: Similarity
messages: Belongs to the asp23 family.

1616788:AR543 RS14965
gene id: 1616788:AR543_RS14965
uniprot id: A0A172ZHQ6
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS03185
gene id: 1616788:AR543_RS03185
uniprot id: A0A172ZBV9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1616788:AR543 RS08700
gene id: 1616788:AR543_RS08700
uniprot id: A0A172ZEH1
names: Similarity
messages: Belongs to the UPF0047 family.

1616788:AR543 RS19390
gene id: 1616788:AR543_RS19390
uniprot id: A0A172ZJY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1616788:AR543 RS12800
gene id: 1616788:AR543_RS12800
uniprot id: A0A172ZGL1
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1616788:AR543 RS11045
gene id: 1616788:AR543_RS11045
uniprot id: A0A172ZFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS23375
gene id: 1616788:AR543_RS23375
uniprot id: A0A1X9T3Y1
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1616788:AR543 RS03235
gene id: 1616788:AR543_RS03235
uniprot id: A0A172ZCR0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1616788:AR543 RS15400
gene id: 1616788:AR543_RS15400
uniprot id: A0A172ZI79
names: Similarity
messages: Belongs to the glutamine synthetase family.

1616788:AR543 RS16275
gene id: 1616788:AR543_RS16275
uniprot id: A0A172ZIC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1616788:AR543 RS22180
gene id: 1616788:AR543_RS22180
uniprot id: A0A172ZL83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1616788:AR543 RS20460
gene id: 1616788:AR543_RS20460
uniprot id: A0A172ZKJ6
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS16315
gene id: 1616788:AR543_RS16315
uniprot id: A0A172ZIM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1616788:AR543 RS16885
gene id: 1616788:AR543_RS16885
uniprot id: A0A172ZJP5
names: Similarity
messages: Belongs to the peptidase U62 family.

1616788:AR543 RS07205
gene id: 1616788:AR543_RS07205
uniprot id: A0A172ZDT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1616788:AR543 RS10585
gene id: 1616788:AR543_RS10585
uniprot id: A0A172ZFJ1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS02095
gene id: 1616788:AR543_RS02095
uniprot id: A0A172ZBB9
names: Similarity
messages: Belongs to the YjdM family.

1616788:AR543 RS08710
gene id: 1616788:AR543_RS08710
uniprot id: A0A172ZEI8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1616788:AR543 RS22845
gene id: 1616788:AR543_RS22845
uniprot id: A0A172ZMZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1616788:AR543 RS15260
gene id: 1616788:AR543_RS15260
uniprot id: A0A172ZHU4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1616788:AR543 RS19875
gene id: 1616788:AR543_RS19875
uniprot id: A0A172ZKG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS00290
gene id: 1616788:AR543_RS00290
uniprot id: A0A172ZB77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS10555
gene id: 1616788:AR543_RS10555
uniprot id: A0A172ZFR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1616788:AR543 RS02235
gene id: 1616788:AR543_RS02235
uniprot id: A0A172ZLR6
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1616788:AR543 RS15385
gene id: 1616788:AR543_RS15385
uniprot id: A0A172ZHX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1616788:AR543 RS09885
gene id: 1616788:AR543_RS09885
uniprot id: A0A172ZG69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1616788:AR543 RS05865
gene id: 1616788:AR543_RS05865
uniprot id: A0A172ZEI4
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

1616788:AR543 RS00360
gene id: 1616788:AR543_RS00360
uniprot id: A0A172ZAW4
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1616788:AR543 RS22565
gene id: 1616788:AR543_RS22565
uniprot id: A0A172ZLF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1616788:AR543 RS00235
gene id: 1616788:AR543_RS00235
uniprot id: A0A172ZB67
names: Similarity
messages: Belongs to the catalase family.

1616788:AR543 RS04055
gene id: 1616788:AR543_RS04055
uniprot id: A0A172ZCC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS20025
gene id: 1616788:AR543_RS20025
uniprot id: A0A172ZK75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1616788:AR543 RS11120
gene id: 1616788:AR543_RS11120
uniprot id: A0A172ZFS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1616788:AR543 RS16375
gene id: 1616788:AR543_RS16375
uniprot id: A0A172ZID9
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. MtnX family.
messages: Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).

1616788:AR543 RS16980
gene id: 1616788:AR543_RS16980
uniprot id: A0A172ZIP8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1616788:AR543 RS16035
gene id: 1616788:AR543_RS16035
uniprot id: A0A172ZII0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS19375
gene id: 1616788:AR543_RS19375
uniprot id: A0A172ZJW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1616788:AR543 RS18050
gene id: 1616788:AR543_RS18050
uniprot id: A0A172ZJ93
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

1616788:AR543 RS02530
gene id: 1616788:AR543_RS02530
uniprot id: A0A172ZBI6
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS21620
gene id: 1616788:AR543_RS21620
uniprot id: A0A172ZL51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS22030
gene id: 1616788:AR543_RS22030
uniprot id: A0A172ZLB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1616788:AR543 RS06420
gene id: 1616788:AR543_RS06420
uniprot id: A0A172ZE60
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS16435
gene id: 1616788:AR543_RS16435
uniprot id: A0A172ZIE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1616788:AR543 RS04915
gene id: 1616788:AR543_RS04915
uniprot id: A0A172ZD23
names: Similarity
messages: Belongs to the UPF0045 family.

1616788:AR543 RS16945
gene id: 1616788:AR543_RS16945
uniprot id: A0A172ZIU3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1616788:AR543 RS18675
gene id: 1616788:AR543_RS18675
uniprot id: A0A172ZKN2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS17090
gene id: 1616788:AR543_RS17090
uniprot id: A0A172ZIS2
names: Similarity
messages: Belongs to the asp23 family.

1616788:AR543 RS10275
gene id: 1616788:AR543_RS10275
uniprot id: A0A172ZGD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1616788:AR543 RS09185
gene id: 1616788:AR543_RS09185
uniprot id: A0A172ZF42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1616788:AR543 RS19580
gene id: 1616788:AR543_RS19580
uniprot id: A0A172ZLG7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1616788:AR543 RS13080
gene id: 1616788:AR543_RS13080
uniprot id: A0A172ZGR2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS10745
gene id: 1616788:AR543_RS10745
uniprot id: A0A172ZGA8
names: Similarity
messages: Belongs to the DinB family.

1616788:AR543 RS22005
gene id: 1616788:AR543_RS22005
uniprot id: A0A172ZL45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1616788:AR543 RS07455
gene id: 1616788:AR543_RS07455
uniprot id: A0A172ZDW3
names: Similarity
messages: Belongs to the asparagine synthetase family.

1616788:AR543 RS09920
gene id: 1616788:AR543_RS09920
uniprot id: A0A172ZF38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1616788:AR543 RS22140
gene id: 1616788:AR543_RS22140
uniprot id: A0A172ZLC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1616788:AR543 RS10015
gene id: 1616788:AR543_RS10015
uniprot id: A0A172ZMC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1616788:AR543 RS11125
gene id: 1616788:AR543_RS11125
uniprot id: A0A172ZGR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1616788:AR543 RS01890
gene id: 1616788:AR543_RS01890
uniprot id: A0A172ZC08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1616788:AR543 RS17030
gene id: 1616788:AR543_RS17030
uniprot id: A0A172ZK56
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1616788:AR543 RS10335
gene id: 1616788:AR543_RS10335
uniprot id: A0A172ZFM6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS10665
gene id: 1616788:AR543_RS10665
uniprot id: A0A172ZFM3
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

1616788:AR543 RS22050
gene id: 1616788:AR543_RS22050
uniprot id: A0A172ZLT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1616788:AR543 RS11105
gene id: 1616788:AR543_RS11105
uniprot id: A0A172ZG52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1616788:AR543 RS18100
gene id: 1616788:AR543_RS18100
uniprot id: A0A172ZJA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1616788:AR543 RS21860
gene id: 1616788:AR543_RS21860
uniprot id: A0A172ZLC9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1616788:AR543 RS08830
gene id: 1616788:AR543_RS08830
uniprot id: A0A172ZEM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1616788:AR543 RS19180
gene id: 1616788:AR543_RS19180
uniprot id: A0A172ZKX3
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS22710
gene id: 1616788:AR543_RS22710
uniprot id: A0A172ZLH1
names: Similarity
messages: Belongs to the FlgM family.

1616788:AR543 RS15395
gene id: 1616788:AR543_RS15395
uniprot id: A0A172ZI17
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1616788:AR543 RS13470
gene id: 1616788:AR543_RS13470
uniprot id: A0A172ZGY2
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS06995
gene id: 1616788:AR543_RS06995
uniprot id: A0A172ZE07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1616788:AR543 RS14905
gene id: 1616788:AR543_RS14905
uniprot id: A0A172ZHP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1616788:AR543 RS12990
gene id: 1616788:AR543_RS12990
uniprot id: A0A172ZHP9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1616788:AR543 RS22085
gene id: 1616788:AR543_RS22085
uniprot id: A0A172ZMB4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1616788:AR543 RS10865
gene id: 1616788:AR543_RS10865
uniprot id: A0A172ZFM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1616788:AR543 RS06435
gene id: 1616788:AR543_RS06435
uniprot id: A0A172ZDC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS20185
gene id: 1616788:AR543_RS20185
uniprot id: A0A172ZKC1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1616788:AR543 RS06850
gene id: 1616788:AR543_RS06850
uniprot id: A0A172ZDJ7
names: Function
messages: Required for transformation and DNA binding.

1616788:AR543 RS08440
gene id: 1616788:AR543_RS08440
uniprot id: A0A172ZFU1
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

1616788:AR543 RS01235
gene id: 1616788:AR543_RS01235
uniprot id: A0A172ZAZ5
names: Similarity
messages: Belongs to the EamA transporter family.

1616788:AR543 RS21465
gene id: 1616788:AR543_RS21465
uniprot id: A0A172ZL22
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS16690
gene id: 1616788:AR543_RS16690
uniprot id: A0A172ZJ84
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1616788:AR543 RS03200
gene id: 1616788:AR543_RS03200
uniprot id: A0A172ZBZ8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1616788:AR543 RS03085
gene id: 1616788:AR543_RS03085
uniprot id: A0A172ZCY0
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS04820
gene id: 1616788:AR543_RS04820
uniprot id: A0A172ZDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1616788:AR543 RS20425
gene id: 1616788:AR543_RS20425
uniprot id: A0A172ZL30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1616788:AR543 RS22480
gene id: 1616788:AR543_RS22480
uniprot id: A0A172ZLM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS21820
gene id: 1616788:AR543_RS21820
uniprot id: A0A172ZLR3
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS10570
gene id: 1616788:AR543_RS10570
uniprot id: A0A172ZG78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Monomer.

1616788:AR543 RS16515
gene id: 1616788:AR543_RS16515
uniprot id: A0A172ZJ58
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1616788:AR543 RS20820
gene id: 1616788:AR543_RS20820
uniprot id: A0A172ZKL8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1616788:AR543 RS01855
gene id: 1616788:AR543_RS01855
uniprot id: A0A172ZB71
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS02745
gene id: 1616788:AR543_RS02745
uniprot id: A0A172ZCS0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1616788:AR543 RS22700
gene id: 1616788:AR543_RS22700
uniprot id: A0A172ZM57
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1616788:AR543 RS15265
gene id: 1616788:AR543_RS15265
uniprot id: A0A172ZHU6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1616788:AR543 RS00155
gene id: 1616788:AR543_RS00155
uniprot id: A0A172ZBG3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1616788:AR543 RS10320
gene id: 1616788:AR543_RS10320
uniprot id: A0A172ZFD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS06090
gene id: 1616788:AR543_RS06090
uniprot id: A0A172ZEB5
names: Similarity
messages: Belongs to the peptidase S8 family.

1616788:AR543 RS13860
gene id: 1616788:AR543_RS13860
uniprot id: A0A172ZI51
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1616788:AR543 RS12160
gene id: 1616788:AR543_RS12160
uniprot id: A0A172ZGA0
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS20860
gene id: 1616788:AR543_RS20860
uniprot id: A0A172ZKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1616788:AR543 RS16570
gene id: 1616788:AR543_RS16570
uniprot id: A0A172ZJ68
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1616788:AR543 RS11950
gene id: 1616788:AR543_RS11950
uniprot id: A0A172ZG74
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1616788:AR543 RS03890
gene id: 1616788:AR543_RS03890
uniprot id: A0A172ZC79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS17970
gene id: 1616788:AR543_RS17970
uniprot id: A0A172ZJ61
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1616788:AR543 RS13210
gene id: 1616788:AR543_RS13210
uniprot id: A0A172ZHT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS19785
gene id: 1616788:AR543_RS19785
uniprot id: A0A172ZK44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS03515
gene id: 1616788:AR543_RS03515
uniprot id: A0A172ZDF3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1616788:AR543 RS18195
gene id: 1616788:AR543_RS18195
uniprot id: A0A172ZJL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1616788:AR543 RS07855
gene id: 1616788:AR543_RS07855
uniprot id: A0A172ZE65
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS02430
gene id: 1616788:AR543_RS02430
uniprot id: A0A172ZCK3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1616788:AR543 RS19520
gene id: 1616788:AR543_RS19520
uniprot id: A0A172ZKA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1616788:AR543 RS03560
gene id: 1616788:AR543_RS03560
uniprot id: A0A172ZCE0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1616788:AR543 RS04530
gene id: 1616788:AR543_RS04530
uniprot id: A0A172ZCX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS22925
gene id: 1616788:AR543_RS22925
uniprot id: A0A172ZLK9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1616788:AR543 RS20645
gene id: 1616788:AR543_RS20645
uniprot id: A0A172ZKT1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS03345
gene id: 1616788:AR543_RS03345
uniprot id: A0A172ZBZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1616788:AR543 RS05830
gene id: 1616788:AR543_RS05830
uniprot id: A0A172ZD29
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1616788:AR543 RS17965
gene id: 1616788:AR543_RS17965
uniprot id: A0A172ZJ70
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1616788:AR543 RS21585
gene id: 1616788:AR543_RS21585
uniprot id: A0A172ZLM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS17250
gene id: 1616788:AR543_RS17250
uniprot id: A0A172ZJ46
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS03285
gene id: 1616788:AR543_RS03285
uniprot id: A0A172ZDB9
names: Similarity
messages: Belongs to the MotB family.

1616788:AR543 RS13575
gene id: 1616788:AR543_RS13575
uniprot id: A0A172ZH56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1616788:AR543 RS20525
gene id: 1616788:AR543_RS20525
uniprot id: A0A172ZLX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS08995
gene id: 1616788:AR543_RS08995
uniprot id: A0A172ZF09
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1616788:AR543 RS22495
gene id: 1616788:AR543_RS22495
uniprot id: A0A172ZM20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1616788:AR543 RS19885
gene id: 1616788:AR543_RS19885
uniprot id: A0A172ZK66
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS19335
gene id: 1616788:AR543_RS19335
uniprot id: A0A172ZJX4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS15465
gene id: 1616788:AR543_RS15465
uniprot id: A0A172ZHX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS05845
gene id: 1616788:AR543_RS05845
uniprot id: A0A172ZE78
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS02490
gene id: 1616788:AR543_RS02490
uniprot id: A0A172ZCL2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS17700
gene id: 1616788:AR543_RS17700
uniprot id: A0A172ZJC0
names: Similarity
messages: Belongs to the peptidase C56 family.

1616788:AR543 RS06535
gene id: 1616788:AR543_RS06535
uniprot id: A0A172ZE79
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1616788:AR543 RS13595
gene id: 1616788:AR543_RS13595
uniprot id: A0A172ZHP2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1616788:AR543 RS22865
gene id: 1616788:AR543_RS22865
uniprot id: A0A172ZLK1
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS19165
gene id: 1616788:AR543_RS19165
uniprot id: A0A172ZJT7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1616788:AR543 RS19800
gene id: 1616788:AR543_RS19800
uniprot id: A0A172ZK93
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1616788:AR543 RS12595
gene id: 1616788:AR543_RS12595
uniprot id: A0A172ZGV3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS05290
gene id: 1616788:AR543_RS05290
uniprot id: A0A172ZCY4
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1616788:AR543 RS12580
gene id: 1616788:AR543_RS12580
uniprot id: A0A172ZHX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1616788:AR543 RS16930
gene id: 1616788:AR543_RS16930
uniprot id: A0A172ZIP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1616788:AR543 RS10130
gene id: 1616788:AR543_RS10130
uniprot id: A0A172ZMV0
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS03915
gene id: 1616788:AR543_RS03915
uniprot id: A0A172ZC84
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1616788:AR543 RS13315
gene id: 1616788:AR543_RS13315
uniprot id: A0A172ZGW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS00345
gene id: 1616788:AR543_RS00345
uniprot id: A0A172ZBU0
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1616788:AR543 RS00270
gene id: 1616788:AR543_RS00270
uniprot id: A0A172ZAH9
names: Similarity
messages: Belongs to the manganese catalase family.

1616788:AR543 RS10490
gene id: 1616788:AR543_RS10490
uniprot id: A0A172ZFF9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1616788:AR543 RS09805
gene id: 1616788:AR543_RS09805
uniprot id: A0A172ZF31
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1616788:AR543 RS22625
gene id: 1616788:AR543_RS22625
uniprot id: A0A172ZLL3
names: Subcellular Location Annotation
messages: Cytoplasm

1616788:AR543 RS04700
gene id: 1616788:AR543_RS04700
uniprot id: A0A172ZCX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1616788:AR543 RS14950
gene id: 1616788:AR543_RS14950
uniprot id: A0A172ZHY6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1616788:AR543 RS14940
gene id: 1616788:AR543_RS14940
uniprot id: A0A172ZHN7
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS05115
gene id: 1616788:AR543_RS05115
uniprot id: A0A172ZDV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1616788:AR543 RS12260
gene id: 1616788:AR543_RS12260
uniprot id: A0A172ZGB4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1616788:AR543 RS19840
gene id: 1616788:AR543_RS19840
uniprot id: A0A172ZK77
names: Similarity
messages: Belongs to the peptidase C56 family.

1616788:AR543 RS03380
gene id: 1616788:AR543_RS03380
uniprot id: A0A172ZD31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS03875
gene id: 1616788:AR543_RS03875
uniprot id: A0A172ZC74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1616788:AR543 RS22160
gene id: 1616788:AR543_RS22160
uniprot id: A0A172ZLW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1616788:AR543 RS03355
gene id: 1616788:AR543_RS03355
uniprot id: A0A172ZCS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1616788:AR543 RS20165
gene id: 1616788:AR543_RS20165
uniprot id: A0A172ZKY8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1616788:AR543 RS18315
gene id: 1616788:AR543_RS18315
uniprot id: A0A172ZK11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1616788:AR543 RS08720
gene id: 1616788:AR543_RS08720
uniprot id: A0A172ZEJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1616788:AR543 RS06370
gene id: 1616788:AR543_RS06370
uniprot id: A0A172ZDD8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS07745
gene id: 1616788:AR543_RS07745
uniprot id: A0A172ZFH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1616788:AR543 RS06885
gene id: 1616788:AR543_RS06885
uniprot id: A0A172ZDR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS19810
gene id: 1616788:AR543_RS19810
uniprot id: A0A172ZLK7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1616788:AR543 RS02495
gene id: 1616788:AR543_RS02495
uniprot id: A0A172ZBL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1616788:AR543 RS22370
gene id: 1616788:AR543_RS22370
uniprot id: A0A172ZLK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1616788:AR543 RS07600
gene id: 1616788:AR543_RS07600
uniprot id: A0A172ZDZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS21565
gene id: 1616788:AR543_RS21565
uniprot id: A0A172ZL39
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1616788:AR543 RS11750
gene id: 1616788:AR543_RS11750
uniprot id: A0A172ZGE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1616788:AR543 RS12710
gene id: 1616788:AR543_RS12710
uniprot id: A0A172ZH91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1616788:AR543 RS12165
gene id: 1616788:AR543_RS12165
uniprot id: A0A172ZGB3
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS22635
gene id: 1616788:AR543_RS22635
uniprot id: A0A172ZMX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1616788:AR543 RS19130
gene id: 1616788:AR543_RS19130
uniprot id: A0A172ZK34
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1616788:AR543 RS19855
gene id: 1616788:AR543_RS19855
uniprot id: A0A172ZKG1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1616788:AR543 RS22250
gene id: 1616788:AR543_RS22250
uniprot id: A0A172ZMR2
names: Similarity
messages: Belongs to the ycf81 family.

1616788:AR543 RS08725
gene id: 1616788:AR543_RS08725
uniprot id: A0A172ZEW2
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS17680
gene id: 1616788:AR543_RS17680
uniprot id: A0A172ZJ17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS00210
gene id: 1616788:AR543_RS00210
uniprot id: A0A172ZAG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1616788:AR543 RS12570
gene id: 1616788:AR543_RS12570
uniprot id: A0A172ZNJ5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1616788:AR543 RS11380
gene id: 1616788:AR543_RS11380
uniprot id: A0A172ZG97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1616788:AR543 RS02835
gene id: 1616788:AR543_RS02835
uniprot id: A0A172ZCH9
names: Similarity
messages: Belongs to the ParB family.

1616788:AR543 RS05435
gene id: 1616788:AR543_RS05435
uniprot id: A0A172ZM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

1616788:AR543 RS20700
gene id: 1616788:AR543_RS20700
uniprot id: A0A172ZKU0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS21775
gene id: 1616788:AR543_RS21775
uniprot id: A0A172ZL05
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS14690
gene id: 1616788:AR543_RS14690
uniprot id: A0A172ZIJ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS22285
gene id: 1616788:AR543_RS22285
uniprot id: A0A172ZMG1
names: Similarity
messages: Belongs to the CtsR family.

1616788:AR543 RS08930
gene id: 1616788:AR543_RS08930
uniprot id: A0A172ZFQ0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1616788:AR543 RS13375
gene id: 1616788:AR543_RS13375
uniprot id: A0A172ZGX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

1616788:AR543 RS20150
gene id: 1616788:AR543_RS20150
uniprot id: A0A172ZKK0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1616788:AR543 RS05905
gene id: 1616788:AR543_RS05905
uniprot id: A0A172ZD90
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1616788:AR543 RS00245
gene id: 1616788:AR543_RS00245
uniprot id: A0A172ZAF8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1616788:AR543 RS16585
gene id: 1616788:AR543_RS16585
uniprot id: A0A172ZIH9
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1616788:AR543 RS17765
gene id: 1616788:AR543_RS17765
uniprot id: A0A172ZJ41
names: Similarity
messages: Belongs to the UPF0473 family.

1616788:AR543 RS03130
gene id: 1616788:AR543_RS03130
uniprot id: A0A172ZBU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1616788:AR543 RS00795
gene id: 1616788:AR543_RS00795
uniprot id: A0A172ZB18
names: Similarity
messages: Belongs to the EamA transporter family.

1616788:AR543 RS11130
gene id: 1616788:AR543_RS11130
uniprot id: A0A172ZFU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1616788:AR543 RS03070
gene id: 1616788:AR543_RS03070
uniprot id: A0A172ZBT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1616788:AR543 RS03625
gene id: 1616788:AR543_RS03625
uniprot id: A0A172ZC36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1616788:AR543 RS06175
gene id: 1616788:AR543_RS06175
uniprot id: A0A172ZD82
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1616788:AR543 RS18295
gene id: 1616788:AR543_RS18295
uniprot id: A0A172ZJH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1616788:AR543 RS16645
gene id: 1616788:AR543_RS16645
uniprot id: A0A172ZIJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1616788:AR543 RS06375
gene id: 1616788:AR543_RS06375
uniprot id: A0A172ZDC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS18015
gene id: 1616788:AR543_RS18015
uniprot id: A0A172ZJ76
names: Similarity
messages: Belongs to the transpeptidase family.

1616788:AR543 RS14560
gene id: 1616788:AR543_RS14560
uniprot id: A0A172ZIH1
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS21480
gene id: 1616788:AR543_RS21480
uniprot id: A0A172ZKV9
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1616788:AR543 RS05200
gene id: 1616788:AR543_RS05200
uniprot id: A0A172ZD71
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1616788:AR543 RS12360
gene id: 1616788:AR543_RS12360
uniprot id: A0A172ZGI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1616788:AR543 RS04500
gene id: 1616788:AR543_RS04500
uniprot id: A0A172ZDL0
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1616788:AR543 RS19905
gene id: 1616788:AR543_RS19905
uniprot id: A0A172ZMV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS19850
gene id: 1616788:AR543_RS19850
uniprot id: A0A172ZKA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS11485
gene id: 1616788:AR543_RS11485
uniprot id: A0A172ZFX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1616788:AR543 RS00370
gene id: 1616788:AR543_RS00370
uniprot id: A0A172ZAH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UbiX/PAD1 family. YclB subfamily.
messages: Homododecamer.
messages: Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase.

1616788:AR543 RS05440
gene id: 1616788:AR543_RS05440
uniprot id: A0A172ZDR3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1616788:AR543 RS15360
gene id: 1616788:AR543_RS15360
uniprot id: A0A172ZIK5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1616788:AR543 RS15090
gene id: 1616788:AR543_RS15090
uniprot id: A0A172ZMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS00690
gene id: 1616788:AR543_RS00690
uniprot id: A0A172ZBZ6
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS11560
gene id: 1616788:AR543_RS11560
uniprot id: A0A172ZGA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1616788:AR543 RS09255
gene id: 1616788:AR543_RS09255
uniprot id: A0A172ZF79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS22225
gene id: 1616788:AR543_RS22225
uniprot id: A0A172ZL76
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1616788:AR543 RS01140
gene id: 1616788:AR543_RS01140
uniprot id: A0A172ZN13
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1616788:AR543 RS15510
gene id: 1616788:AR543_RS15510
uniprot id: A0A172ZI98
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1616788:AR543 RS20745
gene id: 1616788:AR543_RS20745
uniprot id: A0A172ZKJ9
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

1616788:AR543 RS22200
gene id: 1616788:AR543_RS22200
uniprot id: A0A172ZMQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1616788:AR543 RS08655
gene id: 1616788:AR543_RS08655
uniprot id: A0A172ZEH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1616788:AR543 RS00820
gene id: 1616788:AR543_RS00820
uniprot id: A0A172ZB41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS13360
gene id: 1616788:AR543_RS13360
uniprot id: A0A172ZGW3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1616788:AR543 RS08660
gene id: 1616788:AR543_RS08660
uniprot id: A0A172ZFK0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1616788:AR543 RS11300
gene id: 1616788:AR543_RS11300
uniprot id: A0A172ZGV1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1616788:AR543 RS09900
gene id: 1616788:AR543_RS09900
uniprot id: A0A172ZGL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1616788:AR543 RS18065
gene id: 1616788:AR543_RS18065
uniprot id: A0A172ZJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS11635
gene id: 1616788:AR543_RS11635
uniprot id: A0A172ZHF6
names: Similarity
messages: Belongs to the UPF0234 family.

1616788:AR543 RS04495
gene id: 1616788:AR543_RS04495
uniprot id: A0A172ZCH4
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1616788:AR543 RS00350
gene id: 1616788:AR543_RS00350
uniprot id: A0A172ZAH1
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1616788:AR543 RS19625
gene id: 1616788:AR543_RS19625
uniprot id: A0A172ZK62
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1616788:AR543 RS09370
gene id: 1616788:AR543_RS09370
uniprot id: A0A172ZFM0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1616788:AR543 RS17775
gene id: 1616788:AR543_RS17775
uniprot id: A0A172ZJD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS11190
gene id: 1616788:AR543_RS11190
uniprot id: A0A172ZFW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1616788:AR543 RS13290
gene id: 1616788:AR543_RS13290
uniprot id: A0A172ZGV4
names: Subcellular Location Annotation
messages: Cell membrane

1616788:AR543 RS00050
gene id: 1616788:AR543_RS00050
uniprot id: A0A172ZAD5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1616788:AR543 RS07780
gene id: 1616788:AR543_RS07780
uniprot id: A0A172ZF49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS08450
gene id: 1616788:AR543_RS08450
uniprot id: A0A172ZF70
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1616788:AR543 RS12520
gene id: 1616788:AR543_RS12520
uniprot id: A0A172ZHW3
names: Similarity
messages: Belongs to the catalase family.

1616788:AR543 RS10185
gene id: 1616788:AR543_RS10185
uniprot id: A0A172ZF96
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1616788:AR543 RS11090
gene id: 1616788:AR543_RS11090
uniprot id: A0A172ZH58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1616788:AR543 RS08315
gene id: 1616788:AR543_RS08315
uniprot id: A0A172ZEQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1616788:AR543 RS01490
gene id: 1616788:AR543_RS01490
uniprot id: A0A172ZB17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1616788:AR543 RS10000
gene id: 1616788:AR543_RS10000
uniprot id: A0A172ZGP1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1616788:AR543 RS13810
gene id: 1616788:AR543_RS13810
uniprot id: A0A172ZH93
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS22675
gene id: 1616788:AR543_RS22675
uniprot id: A0A172ZMM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1616788:AR543 RS13030
gene id: 1616788:AR543_RS13030
uniprot id: A0A172ZGP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1616788:AR543 RS08355
gene id: 1616788:AR543_RS08355
uniprot id: A0A172ZEE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1616788:AR543 RS10560
gene id: 1616788:AR543_RS10560
uniprot id: A0A172ZGX5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1616788:AR543 RS19385
gene id: 1616788:AR543_RS19385
uniprot id: A0A172ZK78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1616788:AR543 RS05925
gene id: 1616788:AR543_RS05925
uniprot id: A0A172ZDY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1616788:AR543 RS14750
gene id: 1616788:AR543_RS14750
uniprot id: A0A172ZHQ5
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS19265
gene id: 1616788:AR543_RS19265
uniprot id: A0A172ZMN7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1616788:AR543 RS15095
gene id: 1616788:AR543_RS15095
uniprot id: A0A172ZIR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS16265
gene id: 1616788:AR543_RS16265
uniprot id: A0A172ZIC0
names: Similarity
messages: Belongs to the barstar family.

1616788:AR543 RS12890
gene id: 1616788:AR543_RS12890
uniprot id: A0A172ZI28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS20595
gene id: 1616788:AR543_RS20595
uniprot id: A0A172ZKI4
names: Similarity
messages: Belongs to the leucine-binding protein family.

1616788:AR543 RS09815
gene id: 1616788:AR543_RS09815
uniprot id: A0A172ZFG9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1616788:AR543 RS17585
gene id: 1616788:AR543_RS17585
uniprot id: A0A172ZK30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS16710
gene id: 1616788:AR543_RS16710
uniprot id: A0A172ZIK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1616788:AR543 RS00625
gene id: 1616788:AR543_RS00625
uniprot id: A0A172ZAN4
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS17105
gene id: 1616788:AR543_RS17105
uniprot id: A0A172ZMK7
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1616788:AR543 RS21780
gene id: 1616788:AR543_RS21780
uniprot id: A0A172ZL28
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

1616788:AR543 RS09905
gene id: 1616788:AR543_RS09905
uniprot id: A0A172ZF44
names: Similarity
messages: Belongs to the pyruvate kinase family.

1616788:AR543 RS07255
gene id: 1616788:AR543_RS07255
uniprot id: A0A172ZDU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1616788:AR543 RS12215
gene id: 1616788:AR543_RS12215
uniprot id: A0A172ZGC2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1616788:AR543 RS16355
gene id: 1616788:AR543_RS16355
uniprot id: A0A172ZJT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1616788:AR543 RS03245
gene id: 1616788:AR543_RS03245
uniprot id: A0A172ZCA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1616788:AR543 RS19575
gene id: 1616788:AR543_RS19575
uniprot id: A0A172ZKB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1616788:AR543 RS22915
gene id: 1616788:AR543_RS22915
uniprot id: A0A172ZLV5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1616788:AR543 RS01230
gene id: 1616788:AR543_RS01230
uniprot id: A0A172ZBZ4
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1616788:AR543 RS13095
gene id: 1616788:AR543_RS13095
uniprot id: A0A172ZHR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.

1616788:AR543 RS21575
gene id: 1616788:AR543_RS21575
uniprot id: A0A172ZME6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1616788:AR543 RS03125
gene id: 1616788:AR543_RS03125
uniprot id: A0A172ZBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1616788:AR543 RS22125
gene id: 1616788:AR543_RS22125
uniprot id: A0A172ZL58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1616788:AR543 RS21635
gene id: 1616788:AR543_RS21635
uniprot id: A0A172ZMS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1616788:AR543 RS08455
gene id: 1616788:AR543_RS08455
uniprot id: A0A172ZEU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS13270
gene id: 1616788:AR543_RS13270
uniprot id: A0A172ZHU8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS04900
gene id: 1616788:AR543_RS04900
uniprot id: A0A172ZE42
names: Subcellular Location Annotation
messages: Cell membrane

1616788:AR543 RS08690
gene id: 1616788:AR543_RS08690
uniprot id: A0A172ZF99
names: Similarity
messages: Belongs to the IMPACT family.

1616788:AR543 RS05135
gene id: 1616788:AR543_RS05135
uniprot id: A0A172ZCR4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1616788:AR543 RS17705
gene id: 1616788:AR543_RS17705
uniprot id: A0A172ZKH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1616788:AR543 RS03120
gene id: 1616788:AR543_RS03120
uniprot id: A0A172ZC85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1616788:AR543 RS09670
gene id: 1616788:AR543_RS09670
uniprot id: A0A172ZF10
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS00095
gene id: 1616788:AR543_RS00095
uniprot id: A0A172ZAD2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS18385
gene id: 1616788:AR543_RS18385
uniprot id: A0A172ZJE2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1616788:AR543 RS16745
gene id: 1616788:AR543_RS16745
uniprot id: A0A172ZIK6
names: Similarity
messages: Belongs to the MecA family.

1616788:AR543 RS17910
gene id: 1616788:AR543_RS17910
uniprot id: A0A172ZJ52
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1616788:AR543 RS19630
gene id: 1616788:AR543_RS19630
uniprot id: A0A172ZKC5
names: Similarity
messages: Belongs to the TPP enzyme family.

1616788:AR543 RS07170
gene id: 1616788:AR543_RS07170
uniprot id: A0A172ZN89
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1616788:AR543 RS15140
gene id: 1616788:AR543_RS15140
uniprot id: A0A172ZMH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS06215
gene id: 1616788:AR543_RS06215
uniprot id: A0A172ZLY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1616788:AR543 RS10815
gene id: 1616788:AR543_RS10815
uniprot id: A0A172ZFI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1616788:AR543 RS18180
gene id: 1616788:AR543_RS18180
uniprot id: A0A172ZJA9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1616788:AR543 RS01725
gene id: 1616788:AR543_RS01725
uniprot id: A0A172ZBY0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1616788:AR543 RS19860
gene id: 1616788:AR543_RS19860
uniprot id: A0A172ZLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1616788:AR543 RS04640
gene id: 1616788:AR543_RS04640
uniprot id: A0A172ZCM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS16245
gene id: 1616788:AR543_RS16245
uniprot id: A0A172ZIB5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1616788:AR543 RS03810
gene id: 1616788:AR543_RS03810
uniprot id: A0A172ZC67
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1616788:AR543 RS16400
gene id: 1616788:AR543_RS16400
uniprot id: A0A172ZIQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1616788:AR543 RS03795
gene id: 1616788:AR543_RS03795
uniprot id: A0A172ZLU9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1616788:AR543 RS19830
gene id: 1616788:AR543_RS19830
uniprot id: A0A172ZK64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS05915
gene id: 1616788:AR543_RS05915
uniprot id: A0A172ZEJ5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1616788:AR543 RS09890
gene id: 1616788:AR543_RS09890
uniprot id: A0A172ZF76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1616788:AR543 RS16005
gene id: 1616788:AR543_RS16005
uniprot id: A0A172ZJ81
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1616788:AR543 RS11555
gene id: 1616788:AR543_RS11555
uniprot id: A0A172ZG42
names: Similarity
messages: Belongs to the ribF family.

1616788:AR543 RS21455
gene id: 1616788:AR543_RS21455
uniprot id: A0A172ZKW8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1616788:AR543 RS08290
gene id: 1616788:AR543_RS08290
uniprot id: A0A172ZED5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPF0173 family.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS03075
gene id: 1616788:AR543_RS03075
uniprot id: A0A172ZBT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1616788:AR543 RS10670
gene id: 1616788:AR543_RS10670
uniprot id: A0A172ZFT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

1616788:AR543 RS08705
gene id: 1616788:AR543_RS08705
uniprot id: A0A172ZEJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1616788:AR543 RS09640
gene id: 1616788:AR543_RS09640
uniprot id: A0A172ZFS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS14030
gene id: 1616788:AR543_RS14030
uniprot id: A0A172ZH80
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS17320
gene id: 1616788:AR543_RS17320
uniprot id: A0A172ZJ54
names: Subcellular Location Annotation
messages: Cell membrane

1616788:AR543 RS22000
gene id: 1616788:AR543_RS22000
uniprot id: A0A172ZLE5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1616788:AR543 RS16805
gene id: 1616788:AR543_RS16805
uniprot id: A0A172ZIW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1616788:AR543 RS06540
gene id: 1616788:AR543_RS06540
uniprot id: A0A172ZDV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1616788:AR543 RS07180
gene id: 1616788:AR543_RS07180
uniprot id: A0A172ZEK7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1616788:AR543 RS14730
gene id: 1616788:AR543_RS14730
uniprot id: A0A172ZHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS19340
gene id: 1616788:AR543_RS19340
uniprot id: A0A172ZNW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1616788:AR543 RS08410
gene id: 1616788:AR543_RS08410
uniprot id: A0A172ZEF2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1616788:AR543 RS04675
gene id: 1616788:AR543_RS04675
uniprot id: A0A172ZCK2
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

1616788:AR543 RS11430
gene id: 1616788:AR543_RS11430
uniprot id: A0A172ZGA6
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1616788:AR543 RS22685
gene id: 1616788:AR543_RS22685
uniprot id: A0A172ZLR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1616788:AR543 RS12470
gene id: 1616788:AR543_RS12470
uniprot id: A0A172ZHV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS16550
gene id: 1616788:AR543_RS16550
uniprot id: A0A172ZIS6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1616788:AR543 RS18240
gene id: 1616788:AR543_RS18240
uniprot id: A0A172ZJG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1616788:AR543 RS11340
gene id: 1616788:AR543_RS11340
uniprot id: A0A172ZFV9
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1616788:AR543 RS23880
gene id: 1616788:AR543_RS23880
uniprot id: A0A1X9T492
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
messages: Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
messages: Cytoplasm

1616788:AR543 RS20170
gene id: 1616788:AR543_RS20170
uniprot id: A0A172ZKK8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1616788:AR543 RS11535
gene id: 1616788:AR543_RS11535
uniprot id: A0A172ZFY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1616788:AR543 RS08810
gene id: 1616788:AR543_RS08810
uniprot id: A0A172ZEJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1616788:AR543 RS08375
gene id: 1616788:AR543_RS08375
uniprot id: A0A172ZFT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1616788:AR543 RS09440
gene id: 1616788:AR543_RS09440
uniprot id: A0A172ZEX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1616788:AR543 RS20190
gene id: 1616788:AR543_RS20190
uniprot id: A0A172ZLF1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1616788:AR543 RS02680
gene id: 1616788:AR543_RS02680
uniprot id: A0A172ZBM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1616788:AR543 RS22220
gene id: 1616788:AR543_RS22220
uniprot id: A0A172ZL86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1616788:AR543 RS02880
gene id: 1616788:AR543_RS02880
uniprot id: A0A172ZBR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1616788:AR543 RS21305
gene id: 1616788:AR543_RS21305
uniprot id: A0A172ZKT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1616788:AR543 RS03960
gene id: 1616788:AR543_RS03960
uniprot id: A0A172ZDP2
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS19760
gene id: 1616788:AR543_RS19760
uniprot id: A0A172ZK39
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1616788:AR543 RS01160
gene id: 1616788:AR543_RS01160
uniprot id: A0A172ZAW0
names: Similarity
messages: Belongs to the nitroreductase family.

1616788:AR543 RS11160
gene id: 1616788:AR543_RS11160
uniprot id: A0A172ZFQ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1616788:AR543 RS06520
gene id: 1616788:AR543_RS06520
uniprot id: A0A172ZDS4
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS09215
gene id: 1616788:AR543_RS09215
uniprot id: A0A172ZES9
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS11140
gene id: 1616788:AR543_RS11140
uniprot id: A0A172ZH70
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1616788:AR543 RS12225
gene id: 1616788:AR543_RS12225
uniprot id: A0A172ZHC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1616788:AR543 RS20960
gene id: 1616788:AR543_RS20960
uniprot id: A0A172ZKP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1616788:AR543 RS06820
gene id: 1616788:AR543_RS06820
uniprot id: A0A172ZDL1
names: Function
messages: Required for transformation and DNA binding.

1616788:AR543 RS12850
gene id: 1616788:AR543_RS12850
uniprot id: A0A172ZGM1
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1616788:AR543 RS07495
gene id: 1616788:AR543_RS07495
uniprot id: A0A172ZEZ4
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1616788:AR543 RS04280
gene id: 1616788:AR543_RS04280
uniprot id: A0A172ZCD2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1616788:AR543 RS11660
gene id: 1616788:AR543_RS11660
uniprot id: A0A172ZG08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1616788:AR543 RS01330
gene id: 1616788:AR543_RS01330
uniprot id: A0A172ZAZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS12695
gene id: 1616788:AR543_RS12695
uniprot id: A0A172ZHZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1616788:AR543 RS14340
gene id: 1616788:AR543_RS14340
uniprot id: A0A172ZIC9
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1616788:AR543 RS18335
gene id: 1616788:AR543_RS18335
uniprot id: A0A172ZJD8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1616788:AR543 RS15520
gene id: 1616788:AR543_RS15520
uniprot id: A0A172ZHY7
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS13310
gene id: 1616788:AR543_RS13310
uniprot id: A0A172ZGW0
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1616788:AR543 RS03165
gene id: 1616788:AR543_RS03165
uniprot id: A0A172ZBW5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1616788:AR543 RS22265
gene id: 1616788:AR543_RS22265
uniprot id: A0A172ZLJ4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1616788:AR543 RS08750
gene id: 1616788:AR543_RS08750
uniprot id: A0A172ZEY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS00490
gene id: 1616788:AR543_RS00490
uniprot id: A0A172ZBM0
names: Similarity
messages: Belongs to the CdaR family.

1616788:AR543 RS00695
gene id: 1616788:AR543_RS00695
uniprot id: A0A172ZAN1
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS19255
gene id: 1616788:AR543_RS19255
uniprot id: A0A172ZKI7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1616788:AR543 RS14405
gene id: 1616788:AR543_RS14405
uniprot id: A0A172ZHQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS14285
gene id: 1616788:AR543_RS14285
uniprot id: A0A172ZHH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS22785
gene id: 1616788:AR543_RS22785
uniprot id: A0A172ZLT6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1616788:AR543 RS11070
gene id: 1616788:AR543_RS11070
uniprot id: A0A172ZFR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS01785
gene id: 1616788:AR543_RS01785
uniprot id: A0A172ZBK9
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS11285
gene id: 1616788:AR543_RS11285
uniprot id: A0A172ZFS0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1616788:AR543 RS10825
gene id: 1616788:AR543_RS10825
uniprot id: A0A172ZFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1616788:AR543 RS22520
gene id: 1616788:AR543_RS22520
uniprot id: A0A172ZMK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1616788:AR543 RS05680
gene id: 1616788:AR543_RS05680
uniprot id: A0A172ZD11
names: Similarity
messages: Belongs to the universal stress protein A family.

1616788:AR543 RS04995
gene id: 1616788:AR543_RS04995
uniprot id: A0A172ZCT6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1616788:AR543 RS21050
gene id: 1616788:AR543_RS21050
uniprot id: A0A172ZKQ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS17925
gene id: 1616788:AR543_RS17925
uniprot id: A0A172ZJG1
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1616788:AR543 RS00060
gene id: 1616788:AR543_RS00060
uniprot id: A0A172ZBN9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS19325
gene id: 1616788:AR543_RS19325
uniprot id: A0A172ZMX2
names: Subcellular Location Annotation
messages: Cell membrane

1616788:AR543 RS04895
gene id: 1616788:AR543_RS04895
uniprot id: A0A172ZD06
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1616788:AR543 RS03385
gene id: 1616788:AR543_RS03385
uniprot id: A0A172ZC25
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS12030
gene id: 1616788:AR543_RS12030
uniprot id: A0A172ZHM0
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1616788:AR543 RS17045
gene id: 1616788:AR543_RS17045
uniprot id: A0A172ZJ04
names: Similarity
messages: Belongs to the TlyA family.

1616788:AR543 RS21680
gene id: 1616788:AR543_RS21680
uniprot id: A0A172ZL61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS13605
gene id: 1616788:AR543_RS13605
uniprot id: A0A172ZHB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

1616788:AR543 RS09170
gene id: 1616788:AR543_RS09170
uniprot id: A0A172ZFT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

1616788:AR543 RS22605
gene id: 1616788:AR543_RS22605
uniprot id: A0A172ZLF2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS02830
gene id: 1616788:AR543_RS02830
uniprot id: A0A172ZLY8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1616788:AR543 RS15355
gene id: 1616788:AR543_RS15355
uniprot id: A0A172ZHV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1616788:AR543 RS16670
gene id: 1616788:AR543_RS16670
uniprot id: A0A172ZIP4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1616788:AR543 RS08035
gene id: 1616788:AR543_RS08035
uniprot id: A0A172ZEM8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS12700
gene id: 1616788:AR543_RS12700
uniprot id: A0A172ZGI8
names: Similarity
messages: Belongs to the EamA transporter family.

1616788:AR543 RS06360
gene id: 1616788:AR543_RS06360
uniprot id: A0A172ZDB6
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

1616788:AR543 RS10070
gene id: 1616788:AR543_RS10070
uniprot id: A0A172ZGQ0
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS22840
gene id: 1616788:AR543_RS22840
uniprot id: A0A172ZLU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1616788:AR543 RS06050
gene id: 1616788:AR543_RS06050
uniprot id: A0A172ZEL5
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1616788:AR543 RS22825
gene id: 1616788:AR543_RS22825
uniprot id: A0A172ZLK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1616788:AR543 RS09875
gene id: 1616788:AR543_RS09875
uniprot id: A0A172ZF47
names: Similarity
messages: Belongs to the UPF0342 family.

1616788:AR543 RS00175
gene id: 1616788:AR543_RS00175
uniprot id: A0A172ZAE5
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS05045
gene id: 1616788:AR543_RS05045
uniprot id: A0A172ZCQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS19315
gene id: 1616788:AR543_RS19315
uniprot id: A0A172ZJV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1616788:AR543 RS18445
gene id: 1616788:AR543_RS18445
uniprot id: A0A172ZJF2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1616788:AR543 RS07025
gene id: 1616788:AR543_RS07025
uniprot id: A0A172ZDP0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1616788:AR543 RS00140
gene id: 1616788:AR543_RS00140
uniprot id: A0A172ZAE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1616788:AR543 RS10715
gene id: 1616788:AR543_RS10715
uniprot id: A0A172ZGK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS00845
gene id: 1616788:AR543_RS00845
uniprot id: A0A172ZAS5
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS20730
gene id: 1616788:AR543_RS20730
uniprot id: A0A172ZKP6
names: Similarity
messages: Belongs to the thioredoxin family.

1616788:AR543 RS16880
gene id: 1616788:AR543_RS16880
uniprot id: A0A172ZIL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1616788:AR543 RS22065
gene id: 1616788:AR543_RS22065
uniprot id: A0A172ZL55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1616788:AR543 RS01155
gene id: 1616788:AR543_RS01155
uniprot id: A0A172ZAW3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1616788:AR543 RS16485
gene id: 1616788:AR543_RS16485
uniprot id: A0A172ZIF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1616788:AR543 RS21855
gene id: 1616788:AR543_RS21855
uniprot id: A0A172ZL91
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1616788:AR543 RS08055
gene id: 1616788:AR543_RS08055
uniprot id: A0A172ZE87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

1616788:AR543 RS12270
gene id: 1616788:AR543_RS12270
uniprot id: A0A172ZGD2
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

1616788:AR543 RS07610
gene id: 1616788:AR543_RS07610
uniprot id: A0A172ZE00
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1616788:AR543 RS02215
gene id: 1616788:AR543_RS02215
uniprot id: A0A172ZCT0
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS08960
gene id: 1616788:AR543_RS08960
uniprot id: A0A172ZFF3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS18365
gene id: 1616788:AR543_RS18365
uniprot id: A0A172ZJF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1616788:AR543 RS05150
gene id: 1616788:AR543_RS05150
uniprot id: A0A172ZCS4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS15180
gene id: 1616788:AR543_RS15180
uniprot id: A0A172ZIH6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1616788:AR543 RS02425
gene id: 1616788:AR543_RS02425
uniprot id: A0A172ZBG8
names: Similarity
messages: Belongs to the MQO family.

1616788:AR543 RS10355
gene id: 1616788:AR543_RS10355
uniprot id: A0A172ZFR6
names: Similarity
messages: Belongs to the CapA family.

1616788:AR543 RS03860
gene id: 1616788:AR543_RS03860
uniprot id: A0A172ZD10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1616788:AR543 RS22150
gene id: 1616788:AR543_RS22150
uniprot id: A0A172ZMN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1616788:AR543 RS01145
gene id: 1616788:AR543_RS01145
uniprot id: A0A172ZBM3
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1616788:AR543 RS15350
gene id: 1616788:AR543_RS15350
uniprot id: A0A172ZJC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

1616788:AR543 RS18190
gene id: 1616788:AR543_RS18190
uniprot id: A0A172ZJF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1616788:AR543 RS05410
gene id: 1616788:AR543_RS05410
uniprot id: A0A172ZD93
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1616788:AR543 RS22800
gene id: 1616788:AR543_RS22800
uniprot id: A0A172ZLI9
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1616788:AR543 RS08040
gene id: 1616788:AR543_RS08040
uniprot id: A0A172ZE72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1616788:AR543 RS07945
gene id: 1616788:AR543_RS07945
uniprot id: A0A172ZE67
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1616788:AR543 RS10250
gene id: 1616788:AR543_RS10250
uniprot id: A0A172ZG24
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1616788:AR543 RS18115
gene id: 1616788:AR543_RS18115
uniprot id: A0A172ZJ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1616788:AR543 RS03145
gene id: 1616788:AR543_RS03145
uniprot id: A0A172ZCZ0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1616788:AR543 RS11020
gene id: 1616788:AR543_RS11020
uniprot id: A0A172ZGQ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1616788:AR543 RS06395
gene id: 1616788:AR543_RS06395
uniprot id: A0A172ZM94
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS01895
gene id: 1616788:AR543_RS01895
uniprot id: A0A172ZBM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0397 family.
messages: Cell membrane

1616788:AR543 RS22770
gene id: 1616788:AR543_RS22770
uniprot id: A0A172ZLJ6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1616788:AR543 RS14230
gene id: 1616788:AR543_RS14230
uniprot id: A0A172ZHG4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1616788:AR543 RS20965
gene id: 1616788:AR543_RS20965
uniprot id: A0A172ZLD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1616788:AR543 RS21965
gene id: 1616788:AR543_RS21965
uniprot id: A0A172ZL44
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1616788:AR543 RS11280
gene id: 1616788:AR543_RS11280
uniprot id: A0A172ZG77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1616788:AR543 RS17575
gene id: 1616788:AR543_RS17575
uniprot id: A0A172ZJ00
names: Similarity
messages: Belongs to the YicC/YloC family.

1616788:AR543 RS00830
gene id: 1616788:AR543_RS00830
uniprot id: A0A172ZAQ3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1616788:AR543 RS13275
gene id: 1616788:AR543_RS13275
uniprot id: A0A172ZH04
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS08845
gene id: 1616788:AR543_RS08845
uniprot id: A0A172ZEJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1616788:AR543 RS16015
gene id: 1616788:AR543_RS16015
uniprot id: A0A172ZII3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS11290
gene id: 1616788:AR543_RS11290
uniprot id: A0A172ZFV4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1616788:AR543 RS11495
gene id: 1616788:AR543_RS11495
uniprot id: A0A172ZFZ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS03340
gene id: 1616788:AR543_RS03340
uniprot id: A0A172ZDC9
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1616788:AR543 RS00260
gene id: 1616788:AR543_RS00260
uniprot id: A0A172ZLM9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1616788:AR543 RS02600
gene id: 1616788:AR543_RS02600
uniprot id: A0A172ZBN4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS12845
gene id: 1616788:AR543_RS12845
uniprot id: A0A172ZGY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1616788:AR543 RS03635
gene id: 1616788:AR543_RS03635
uniprot id: A0A172ZCH3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1616788:AR543 RS08015
gene id: 1616788:AR543_RS08015
uniprot id: A0A172ZEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS01580
gene id: 1616788:AR543_RS01580
uniprot id: A0A172ZC49
names: Subcellular Location Annotation
messages: Cell membrane

1616788:AR543 RS00115
gene id: 1616788:AR543_RS00115
uniprot id: A0A172ZAQ2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1616788:AR543 RS20665
gene id: 1616788:AR543_RS20665
uniprot id: A0A172ZLP0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1616788:AR543 RS11110
gene id: 1616788:AR543_RS11110
uniprot id: A0A172ZFP3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1616788:AR543 RS09735
gene id: 1616788:AR543_RS09735
uniprot id: A0A172ZG41
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.

1616788:AR543 RS06250
gene id: 1616788:AR543_RS06250
uniprot id: A0A172ZDP7
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS07675
gene id: 1616788:AR543_RS07675
uniprot id: A0A172ZEE3
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1616788:AR543 RS01600
gene id: 1616788:AR543_RS01600
uniprot id: A0A172ZB36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1616788:AR543 RS19690
gene id: 1616788:AR543_RS19690
uniprot id: A0A172ZKD4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1616788:AR543 RS10990
gene id: 1616788:AR543_RS10990
uniprot id: A0A172ZGE7
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1616788:AR543 RS13530
gene id: 1616788:AR543_RS13530
uniprot id: A0A172ZMD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS15345
gene id: 1616788:AR543_RS15345
uniprot id: A0A172ZI70
names: Similarity
messages: Belongs to the FPG family.

1616788:AR543 RS13240
gene id: 1616788:AR543_RS13240
uniprot id: A0A172ZH50
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS22810
gene id: 1616788:AR543_RS22810
uniprot id: A0A172ZLT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1616788:AR543 RS22075
gene id: 1616788:AR543_RS22075
uniprot id: A0A172ZL49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1616788:AR543 RS15475
gene id: 1616788:AR543_RS15475
uniprot id: A0A172ZI89
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1616788:AR543 RS20925
gene id: 1616788:AR543_RS20925
uniprot id: A0A172ZKN7
names: Similarity
messages: Belongs to the transpeptidase family.

1616788:AR543 RS09855
gene id: 1616788:AR543_RS09855
uniprot id: A0A172ZF35
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1616788:AR543 RS19300
gene id: 1616788:AR543_RS19300
uniprot id: A0A172ZK04
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS07940
gene id: 1616788:AR543_RS07940
uniprot id: A0A172ZE53
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1616788:AR543 RS11260
gene id: 1616788:AR543_RS11260
uniprot id: A0A172ZG44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1616788:AR543 RS14865
gene id: 1616788:AR543_RS14865
uniprot id: A0A172ZJ33
names: Similarity
messages: Belongs to the peptidase C40 family.

1616788:AR543 RS05555
gene id: 1616788:AR543_RS05555
uniprot id: A0A172ZDT4
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS06255
gene id: 1616788:AR543_RS06255
uniprot id: A0A172ZD96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1616788:AR543 RS02785
gene id: 1616788:AR543_RS02785
uniprot id: A0A172ZBN8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1616788:AR543 RS08650
gene id: 1616788:AR543_RS08650
uniprot id: A0A172ZEI5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1616788:AR543 RS17270
gene id: 1616788:AR543_RS17270
uniprot id: A0A172ZJ43
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.

1616788:AR543 RS01840
gene id: 1616788:AR543_RS01840
uniprot id: A0A172ZC01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1616788:AR543 RS11595
gene id: 1616788:AR543_RS11595
uniprot id: A0A172ZG01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1616788:AR543 RS18155
gene id: 1616788:AR543_RS18155
uniprot id: A0A172ZJB6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1616788:AR543 RS10925
gene id: 1616788:AR543_RS10925
uniprot id: A0A172ZGD7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS22165
gene id: 1616788:AR543_RS22165
uniprot id: A0A172ZLH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1616788:AR543 RS11880
gene id: 1616788:AR543_RS11880
uniprot id: A0A172ZGU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1616788:AR543 RS03665
gene id: 1616788:AR543_RS03665
uniprot id: A0A172ZC64
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1616788:AR543 RS10435
gene id: 1616788:AR543_RS10435
uniprot id: A0A172ZGG2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS20195
gene id: 1616788:AR543_RS20195
uniprot id: A0A172ZKF4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1616788:AR543 RS10510
gene id: 1616788:AR543_RS10510
uniprot id: A0A172ZGW5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1616788:AR543 RS16770
gene id: 1616788:AR543_RS16770
uniprot id: A0A172ZIK4
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS21420
gene id: 1616788:AR543_RS21420
uniprot id: A0A172ZMC2
names: Subcellular Location Annotation
messages: cell wall

1616788:AR543 RS14800
gene id: 1616788:AR543_RS14800
uniprot id: A0A172ZHR4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1616788:AR543 RS03265
gene id: 1616788:AR543_RS03265
uniprot id: A0A172ZBX1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS14440
gene id: 1616788:AR543_RS14440
uniprot id: A0A172ZHF0
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS07315
gene id: 1616788:AR543_RS07315
uniprot id: A0A172ZDU0
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1616788:AR543 RS13320
gene id: 1616788:AR543_RS13320
uniprot id: A0A172ZHV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1616788:AR543 RS02700
gene id: 1616788:AR543_RS02700
uniprot id: A0A172ZBQ5
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS18300
gene id: 1616788:AR543_RS18300
uniprot id: A0A172ZJN3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1616788:AR543 RS03405
gene id: 1616788:AR543_RS03405
uniprot id: A0A172ZC05
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1616788:AR543 RS12815
gene id: 1616788:AR543_RS12815
uniprot id: A0A172ZHL9
names: Similarity
messages: Belongs to the peptidase C40 family.

1616788:AR543 RS19825
gene id: 1616788:AR543_RS19825
uniprot id: A0A172ZKF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS03360
gene id: 1616788:AR543_RS03360
uniprot id: A0A172ZCC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1616788:AR543 RS22275
gene id: 1616788:AR543_RS22275
uniprot id: A0A172ZL88
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

1616788:AR543 RS20335
gene id: 1616788:AR543_RS20335
uniprot id: A0A172ZLH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1616788:AR543 RS19805
gene id: 1616788:AR543_RS19805
uniprot id: A0A172ZKF2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1616788:AR543 RS22095
gene id: 1616788:AR543_RS22095
uniprot id: A0A172ZLG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1616788:AR543 RS20115
gene id: 1616788:AR543_RS20115
uniprot id: A0A172ZKJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1616788:AR543 RS12740
gene id: 1616788:AR543_RS12740
uniprot id: A0A172ZGK0
names: Similarity
messages: Belongs to the peptidase S66 family.

1616788:AR543 RS16460
gene id: 1616788:AR543_RS16460
uniprot id: A0A172ZIF6
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS10495
gene id: 1616788:AR543_RS10495
uniprot id: A0A172ZGG7
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS02790
gene id: 1616788:AR543_RS02790
uniprot id: A0A172ZBP2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1616788:AR543 RS19400
gene id: 1616788:AR543_RS19400
uniprot id: A0A172ZJZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1616788:AR543 RS12485
gene id: 1616788:AR543_RS12485
uniprot id: A0A172ZGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS07210
gene id: 1616788:AR543_RS07210
uniprot id: A0A172ZDS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1616788:AR543 RS14710
gene id: 1616788:AR543_RS14710
uniprot id: A0A172ZHJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1616788:AR543 RS20710
gene id: 1616788:AR543_RS20710
uniprot id: A0A172ZMX9
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS21840
gene id: 1616788:AR543_RS21840
uniprot id: A0A172ZL16
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1616788:AR543 RS11410
gene id: 1616788:AR543_RS11410
uniprot id: A0A172ZG76
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1616788:AR543 RS07890
gene id: 1616788:AR543_RS07890
uniprot id: A0A172ZE59
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS00280
gene id: 1616788:AR543_RS00280
uniprot id: A0A172ZBT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1616788:AR543 RS09190
gene id: 1616788:AR543_RS09190
uniprot id: A0A172ZG71
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1616788:AR543 RS21015
gene id: 1616788:AR543_RS21015
uniprot id: A0A172ZKQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS00365
gene id: 1616788:AR543_RS00365
uniprot id: A0A172ZAH8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1616788:AR543 RS15965
gene id: 1616788:AR543_RS15965
uniprot id: A0A172ZJM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS17280
gene id: 1616788:AR543_RS17280
uniprot id: A0A172ZIU9
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1616788:AR543 RS20690
gene id: 1616788:AR543_RS20690
uniprot id: A0A172ZKI9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1616788:AR543 RS01000
gene id: 1616788:AR543_RS01000
uniprot id: A0A172ZAT5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1616788:AR543 RS13580
gene id: 1616788:AR543_RS13580
uniprot id: A0A172ZHB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1616788:AR543 RS09510
gene id: 1616788:AR543_RS09510
uniprot id: A0A172ZF03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS03180
gene id: 1616788:AR543_RS03180
uniprot id: A0A172ZBV7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1616788:AR543 RS01675
gene id: 1616788:AR543_RS01675
uniprot id: A0A172ZB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1616788:AR543 RS04150
gene id: 1616788:AR543_RS04150
uniprot id: A0A172ZD51
names: Similarity
messages: Belongs to the peptidase C40 family.

1616788:AR543 RS10720
gene id: 1616788:AR543_RS10720
uniprot id: A0A172ZFM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS00590
gene id: 1616788:AR543_RS00590
uniprot id: A0A172ZN10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS03550
gene id: 1616788:AR543_RS03550
uniprot id: A0A172ZD57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1616788:AR543 RS00505
gene id: 1616788:AR543_RS00505
uniprot id: A0A172ZBW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS06145
gene id: 1616788:AR543_RS06145
uniprot id: A0A172ZD98
names: Similarity
messages: Belongs to the serpin family.

1616788:AR543 RS08070
gene id: 1616788:AR543_RS08070
uniprot id: A0A172ZEA6
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1616788:AR543 RS13335
gene id: 1616788:AR543_RS13335
uniprot id: A0A172ZH69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS05625
gene id: 1616788:AR543_RS05625
uniprot id: A0A172ZDE5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS04855
gene id: 1616788:AR543_RS04855
uniprot id: A0A172ZDG7
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

1616788:AR543 RS15275
gene id: 1616788:AR543_RS15275
uniprot id: A0A172ZIV4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1616788:AR543 RS01015
gene id: 1616788:AR543_RS01015
uniprot id: A0A172ZB56
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS00520
gene id: 1616788:AR543_RS00520
uniprot id: A0A172ZAZ4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

1616788:AR543 RS02540
gene id: 1616788:AR543_RS02540
uniprot id: A0A172ZCM1
names: Subcellular Location Annotation
messages: Cell membrane

1616788:AR543 RS06810
gene id: 1616788:AR543_RS06810
uniprot id: A0A172ZDZ8
names: Similarity
messages: Belongs to the DCK/DGK family.

1616788:AR543 RS05580
gene id: 1616788:AR543_RS05580
uniprot id: A0A172ZD00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS10285
gene id: 1616788:AR543_RS10285
uniprot id: A0A172ZFL7
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1616788:AR543 RS14935
gene id: 1616788:AR543_RS14935
uniprot id: A0A172ZJ44
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS01680
gene id: 1616788:AR543_RS01680
uniprot id: A0A172ZB42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1616788:AR543 RS00355
gene id: 1616788:AR543_RS00355
uniprot id: A0A172ZB87
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1616788:AR543 RS20435
gene id: 1616788:AR543_RS20435
uniprot id: A0A172ZKF1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS01410
gene id: 1616788:AR543_RS01410
uniprot id: A0A172ZC21
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1616788:AR543 RS02315
gene id: 1616788:AR543_RS02315
uniprot id: A0A172ZBF0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1616788:AR543 RS02015
gene id: 1616788:AR543_RS02015
uniprot id: A0A172ZBA5
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS06900
gene id: 1616788:AR543_RS06900
uniprot id: A0A172ZDK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

1616788:AR543 RS07740
gene id: 1616788:AR543_RS07740
uniprot id: A0A172ZM15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS18060
gene id: 1616788:AR543_RS18060
uniprot id: A0A172ZJI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1616788:AR543 RS06150
gene id: 1616788:AR543_RS06150
uniprot id: A0A172ZD85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1616788:AR543 RS20725
gene id: 1616788:AR543_RS20725
uniprot id: A0A172ZLQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1616788:AR543 RS17040
gene id: 1616788:AR543_RS17040
uniprot id: A0A172ZJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1616788:AR543 RS09240
gene id: 1616788:AR543_RS09240
uniprot id: A0A172ZG81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1616788:AR543 RS02770
gene id: 1616788:AR543_RS02770
uniprot id: A0A172ZCG7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1616788:AR543 RS20585
gene id: 1616788:AR543_RS20585
uniprot id: A0A172ZL59
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS22830
gene id: 1616788:AR543_RS22830
uniprot id: A0A172ZMR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1616788:AR543 RS00715
gene id: 1616788:AR543_RS00715
uniprot id: A0A172ZAN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1616788:AR543 RS06210
gene id: 1616788:AR543_RS06210
uniprot id: A0A172ZEC8
names: Similarity
messages: Belongs to the ThiD family.

1616788:AR543 RS08025
gene id: 1616788:AR543_RS08025
uniprot id: A0A172ZE71
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

1616788:AR543 RS11875
gene id: 1616788:AR543_RS11875
uniprot id: A0A172ZG38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1616788:AR543 RS18280
gene id: 1616788:AR543_RS18280
uniprot id: A0A172ZJC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

1616788:AR543 RS09025
gene id: 1616788:AR543_RS09025
uniprot id: A0A172ZEP8
names: Similarity
messages: Belongs to the UPF0311 family.

1616788:AR543 RS13070
gene id: 1616788:AR543_RS13070
uniprot id: A0A172ZHE9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS00145
gene id: 1616788:AR543_RS00145
uniprot id: A0A172ZAE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1616788:AR543 RS02275
gene id: 1616788:AR543_RS02275
uniprot id: A0A172ZBG7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1616788:AR543 RS13835
gene id: 1616788:AR543_RS13835
uniprot id: A0A172ZHT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

1616788:AR543 RS22055
gene id: 1616788:AR543_RS22055
uniprot id: A0A172ZLF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1616788:AR543 RS11500
gene id: 1616788:AR543_RS11500
uniprot id: A0A172ZGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1616788:AR543 RS19915
gene id: 1616788:AR543_RS19915
uniprot id: A0A172ZLM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1616788:AR543 RS00475
gene id: 1616788:AR543_RS00475
uniprot id: A0A172ZAJ9
names: Similarity
messages: Belongs to the LOG family.

1616788:AR543 RS20590
gene id: 1616788:AR543_RS20590
uniprot id: A0A172ZKS0
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS12980
gene id: 1616788:AR543_RS12980
uniprot id: A0A172ZGP0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1616788:AR543 RS03255
gene id: 1616788:AR543_RS03255
uniprot id: A0A172ZBW9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1616788:AR543 RS18055
gene id: 1616788:AR543_RS18055
uniprot id: A0A172ZJV9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1616788:AR543 RS05345
gene id: 1616788:AR543_RS05345
uniprot id: A0A172ZM63
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS02345
gene id: 1616788:AR543_RS02345
uniprot id: A0A172ZC87
names: Subcellular Location Annotation
messages: Membrane

1616788:AR543 RS13545
gene id: 1616788:AR543_RS13545
uniprot id: A0A172ZHN6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.