161398:PP2015 RS01410
gene id: 161398:PP2015_RS01410
uniprot id: A0A0S2JXF0
names: Similarity
messages: Belongs to the UPF0047 family.

161398:PP2015 RS13680
gene id: 161398:PP2015_RS13680
uniprot id: A0A0S2K4A4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

161398:PP2015 RS03970
gene id: 161398:PP2015_RS03970
uniprot id: A0A0S2JZ64
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

161398:PP2015 RS08880
gene id: 161398:PP2015_RS08880
uniprot id: A0A0S2K188
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

161398:PP2015 RS16665
gene id: 161398:PP2015_RS16665
uniprot id: A0A0S2K5X4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS21410
gene id: 161398:PP2015_RS21410
uniprot id: A0A0S2K985
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

161398:PP2015 RS09760
gene id: 161398:PP2015_RS09760
uniprot id: A0A0S2K2R9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

161398:PP2015 RS20140
gene id: 161398:PP2015_RS20140
uniprot id: A0A0S2K863
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

161398:PP2015 RS11735
gene id: 161398:PP2015_RS11735
uniprot id: A0A0S2K423
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

161398:PP2015 RS18175
gene id: 161398:PP2015_RS18175
uniprot id: A0A0S2K6H9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

161398:PP2015 RS13585
gene id: 161398:PP2015_RS13585
uniprot id: A0A0S2K3R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

161398:PP2015 RS14205
gene id: 161398:PP2015_RS14205
uniprot id: A0A0S2K5C7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

161398:PP2015 RS15660
gene id: 161398:PP2015_RS15660
uniprot id: A0A0S2K6E4
names: Subcellular Location Annotation
messages: Nucleus

161398:PP2015 RS14590
gene id: 161398:PP2015_RS14590
uniprot id: A0A4V2EJR1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS10035
gene id: 161398:PP2015_RS10035
uniprot id: A0A0S2K330
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

161398:PP2015 RS01320
gene id: 161398:PP2015_RS01320
uniprot id: A0A0S2JXD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

161398:PP2015 RS01910
gene id: 161398:PP2015_RS01910
uniprot id: A0A0S2JXZ1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

161398:PP2015 RS03430
gene id: 161398:PP2015_RS03430
uniprot id: A0A0S2JYV1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).

161398:PP2015 RS18530
gene id: 161398:PP2015_RS18530
uniprot id: A0A0S2K6P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

161398:PP2015 RS04970
gene id: 161398:PP2015_RS04970
uniprot id: A0A0S2K099
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

161398:PP2015 RS01355
gene id: 161398:PP2015_RS01355
uniprot id: A0A0S2JYC4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

161398:PP2015 RS02585
gene id: 161398:PP2015_RS02585
uniprot id: A0A0S2JZ01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

161398:PP2015 RS05065
gene id: 161398:PP2015_RS05065
uniprot id: A0A0S2K0E8
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

161398:PP2015 RS01245
gene id: 161398:PP2015_RS01245
uniprot id: A0A0S2JXI3
names: Similarity
messages: Belongs to the CutA family.

161398:PP2015 RS16175
gene id: 161398:PP2015_RS16175
uniprot id: A0A0S2K6P6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

161398:PP2015 RS20005
gene id: 161398:PP2015_RS20005
uniprot id: A0A0S2K8D8
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

161398:PP2015 RS21340
gene id: 161398:PP2015_RS21340
uniprot id: A0A0S2K8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

161398:PP2015 RS00055
gene id: 161398:PP2015_RS00055
uniprot id: A0A0S2JX29
names: Similarity
messages: Belongs to the transglycosylase Slt family.

161398:PP2015 RS05660
gene id: 161398:PP2015_RS05660
uniprot id: A0A0S2K0C6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

161398:PP2015 RS08845
gene id: 161398:PP2015_RS08845
uniprot id: A0A0S2K2I8
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

161398:PP2015 RS09000
gene id: 161398:PP2015_RS09000
uniprot id: A0A0S2K209
names: Similarity
messages: Belongs to the peptidase S41A family.

161398:PP2015 RS20365
gene id: 161398:PP2015_RS20365
uniprot id: A0A0S2K8W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

161398:PP2015 RS06745
gene id: 161398:PP2015_RS06745
uniprot id: A0A0S2K1A3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS15110
gene id: 161398:PP2015_RS15110
uniprot id: A0A0S2K516
names: Similarity
messages: Belongs to the SAICAR synthetase family.

161398:PP2015 RS11110
gene id: 161398:PP2015_RS11110
uniprot id: A0A0S2K2H9
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

161398:PP2015 RS14270
gene id: 161398:PP2015_RS14270
uniprot id: A0A0S2K4N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

161398:PP2015 RS12685
gene id: 161398:PP2015_RS12685
uniprot id: A0A0S2K4J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

161398:PP2015 RS12805
gene id: 161398:PP2015_RS12805
uniprot id: A0A0S2K449
names: Similarity
messages: Belongs to the PspA/IM30 family.

161398:PP2015 RS01405
gene id: 161398:PP2015_RS01405
uniprot id: A0A0S2JXQ6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

161398:PP2015 RS15405
gene id: 161398:PP2015_RS15405
uniprot id: A0A0S2K5T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

161398:PP2015 RS11045
gene id: 161398:PP2015_RS11045
uniprot id: A0A0S2K363
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS13745
gene id: 161398:PP2015_RS13745
uniprot id: A0A0S2K4V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

161398:PP2015 RS03450
gene id: 161398:PP2015_RS03450
uniprot id: A0A0S2JYP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS09735
gene id: 161398:PP2015_RS09735
uniprot id: A0A0S2K380
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

161398:PP2015 RS10390
gene id: 161398:PP2015_RS10390
uniprot id: A0A0S2K2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

161398:PP2015 RS07850
gene id: 161398:PP2015_RS07850
uniprot id: A0A0S2K0K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

161398:PP2015 RS13665
gene id: 161398:PP2015_RS13665
uniprot id: A0A0S2K4U4
names: Similarity
messages: Belongs to the MotB family.

161398:PP2015 RS13945
gene id: 161398:PP2015_RS13945
uniprot id: A0A0S2K4A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

161398:PP2015 RS00645
gene id: 161398:PP2015_RS00645
uniprot id: A0A0S2JXB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

161398:PP2015 RS04915
gene id: 161398:PP2015_RS04915
uniprot id: A0A0S2K001
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

161398:PP2015 RS10635
gene id: 161398:PP2015_RS10635
uniprot id: A0A0S2K2Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

161398:PP2015 RS10625
gene id: 161398:PP2015_RS10625
uniprot id: A0A0S2K3A6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS14500
gene id: 161398:PP2015_RS14500
uniprot id: A0A0S2K4B0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS03740
gene id: 161398:PP2015_RS03740
uniprot id: A0A0S2JZP2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

161398:PP2015 RS12860
gene id: 161398:PP2015_RS12860
uniprot id: A0A0S2K4H5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

161398:PP2015 RS04875
gene id: 161398:PP2015_RS04875
uniprot id: A0A0S2JZK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

161398:PP2015 RS04435
gene id: 161398:PP2015_RS04435
uniprot id: A0A0S2JZ80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

161398:PP2015 RS15365
gene id: 161398:PP2015_RS15365
uniprot id: A0A0S2K522
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

161398:PP2015 RS09980
gene id: 161398:PP2015_RS09980
uniprot id: A0A0S2K319
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

161398:PP2015 RS14495
gene id: 161398:PP2015_RS14495
uniprot id: A0A0S2K4X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

161398:PP2015 RS15260
gene id: 161398:PP2015_RS15260
uniprot id: A0A5R9Q8A4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS01030
gene id: 161398:PP2015_RS01030
uniprot id: A0A0S2JY49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

161398:PP2015 RS12840
gene id: 161398:PP2015_RS12840
uniprot id: A0A0S2K4P9
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS01315
gene id: 161398:PP2015_RS01315
uniprot id: A0A0S2JXP2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

161398:PP2015 RS13700
gene id: 161398:PP2015_RS13700
uniprot id: A0A0S2K524
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

161398:PP2015 RS14995
gene id: 161398:PP2015_RS14995
uniprot id: A0A0S2K5U3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

161398:PP2015 RS15275
gene id: 161398:PP2015_RS15275
uniprot id: A0A0S2K5E5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

161398:PP2015 RS08990
gene id: 161398:PP2015_RS08990
uniprot id: A0A0S2K2J6
names: Similarity
messages: Belongs to the peptidase M1 family.

161398:PP2015 RS14860
gene id: 161398:PP2015_RS14860
uniprot id: A0A0S2K5H3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161398:PP2015 RS18065
gene id: 161398:PP2015_RS18065
uniprot id: A0A0S2K6C9
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS14015
gene id: 161398:PP2015_RS14015
uniprot id: A0A0S2K585
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

161398:PP2015 RS13710
gene id: 161398:PP2015_RS13710
uniprot id: A0A0S2K4D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

161398:PP2015 RS10935
gene id: 161398:PP2015_RS10935
uniprot id: A0A0S2K2D4
names: Similarity
messages: Belongs to the histone deacetylase family.

161398:PP2015 RS09595
gene id: 161398:PP2015_RS09595
uniprot id: A0A0S2K2B6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

161398:PP2015 RS15240
gene id: 161398:PP2015_RS15240
uniprot id: A0A0S2K5A4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

161398:PP2015 RS14280
gene id: 161398:PP2015_RS14280
uniprot id: A0A0S2K4V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

161398:PP2015 RS17550
gene id: 161398:PP2015_RS17550
uniprot id: A0A0S2K6M4
names: Similarity
messages: Belongs to the UPF0178 family.

161398:PP2015 RS04295
gene id: 161398:PP2015_RS04295
uniprot id: A0A0S2JZ22
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS08170
gene id: 161398:PP2015_RS08170
uniprot id: A0A0S2K0R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

161398:PP2015 RS05545
gene id: 161398:PP2015_RS05545
uniprot id: A0A0S2JZU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS13185
gene id: 161398:PP2015_RS13185
uniprot id: A0A0S2K458
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

161398:PP2015 RS12690
gene id: 161398:PP2015_RS12690
uniprot id: A0A0S2K3Y9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

161398:PP2015 RS10190
gene id: 161398:PP2015_RS10190
uniprot id: A0A0S2K361
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

161398:PP2015 RS14925
gene id: 161398:PP2015_RS14925
uniprot id: A0A0S2K5T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

161398:PP2015 RS03365
gene id: 161398:PP2015_RS03365
uniprot id: A0A0S2JYM9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS01005
gene id: 161398:PP2015_RS01005
uniprot id: A0A0S2JXX4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

161398:PP2015 RS10445
gene id: 161398:PP2015_RS10445
uniprot id: A0A0S2K3C1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

161398:PP2015 RS09450
gene id: 161398:PP2015_RS09450
uniprot id: A0A0S2K2T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

161398:PP2015 RS08295
gene id: 161398:PP2015_RS08295
uniprot id: A0A0S2K2F2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

161398:PP2015 RS06190
gene id: 161398:PP2015_RS06190
uniprot id: A0A0S2K042
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS13400
gene id: 161398:PP2015_RS13400
uniprot id: A0A0S2K4D3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS02825
gene id: 161398:PP2015_RS02825
uniprot id: A0A0S2JZ46
names: Similarity
messages: Belongs to the peptidase M17 family.

161398:PP2015 RS11025
gene id: 161398:PP2015_RS11025
uniprot id: A0A0S2K387
names: Similarity
messages: Belongs to the GST superfamily.

161398:PP2015 RS13195
gene id: 161398:PP2015_RS13195
uniprot id: A0A0S2K573
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

161398:PP2015 RS03905
gene id: 161398:PP2015_RS03905
uniprot id: A0A0S2JZQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

161398:PP2015 RS21385
gene id: 161398:PP2015_RS21385
uniprot id: A0A0S2K8W0
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

161398:PP2015 RS08995
gene id: 161398:PP2015_RS08995
uniprot id: A0A0S2K1L2
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS13600
gene id: 161398:PP2015_RS13600
uniprot id: A0A0S2K3T4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

161398:PP2015 RS10675
gene id: 161398:PP2015_RS10675
uniprot id: A0A0S2K3G8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

161398:PP2015 RS16845
gene id: 161398:PP2015_RS16845
uniprot id: A0A0S2K6U7
names: Similarity
messages: Belongs to the peptidase C56 family.

161398:PP2015 RS02285
gene id: 161398:PP2015_RS02285
uniprot id: A0A0S2JXU3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

161398:PP2015 RS13450
gene id: 161398:PP2015_RS13450
uniprot id: A0A0S2K3Q4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

161398:PP2015 RS10810
gene id: 161398:PP2015_RS10810
uniprot id: A0A0S2K3I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS06820
gene id: 161398:PP2015_RS06820
uniprot id: A0A0S2K0Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

161398:PP2015 RS13025
gene id: 161398:PP2015_RS13025
uniprot id: A0A0S2K4R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

161398:PP2015 RS01025
gene id: 161398:PP2015_RS01025
uniprot id: A0A0S2JY81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

161398:PP2015 RS14680
gene id: 161398:PP2015_RS14680
uniprot id: A0A0S2K4W0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

161398:PP2015 RS04905
gene id: 161398:PP2015_RS04905
uniprot id: A0A0S2K0D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

161398:PP2015 RS02705
gene id: 161398:PP2015_RS02705
uniprot id: A0A0S2JY30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

161398:PP2015 RS14880
gene id: 161398:PP2015_RS14880
uniprot id: A0A0S2K4W9
names: Similarity
messages: Belongs to the HesB/IscA family.

161398:PP2015 RS08550
gene id: 161398:PP2015_RS08550
uniprot id: A0A0S2K2A5
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

161398:PP2015 RS17370
gene id: 161398:PP2015_RS17370
uniprot id: A0A0S2K6H5
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

161398:PP2015 RS19405
gene id: 161398:PP2015_RS19405
uniprot id: A0A0S2K7V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

161398:PP2015 RS13995
gene id: 161398:PP2015_RS13995
uniprot id: A0A0S2K418
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

161398:PP2015 RS17265
gene id: 161398:PP2015_RS17265
uniprot id: A0A0S2K6M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

161398:PP2015 RS20635
gene id: 161398:PP2015_RS20635
uniprot id: A0A0S2K7Z1
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

161398:PP2015 RS10580
gene id: 161398:PP2015_RS10580
uniprot id: A0A0S2K3F4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS05795
gene id: 161398:PP2015_RS05795
uniprot id: A0A0S2K0P9
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

161398:PP2015 RS04880
gene id: 161398:PP2015_RS04880
uniprot id: A0A0S2JZF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

161398:PP2015 RS07470
gene id: 161398:PP2015_RS07470
uniprot id: A0A0S2K0X6
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS00060
gene id: 161398:PP2015_RS00060
uniprot id: A0A0S2JXA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

161398:PP2015 RS20590
gene id: 161398:PP2015_RS20590
uniprot id: A0A0S2K8R7
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS07225
gene id: 161398:PP2015_RS07225
uniprot id: A0A0S2K0V6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

161398:PP2015 RS06855
gene id: 161398:PP2015_RS06855
uniprot id: A0A0S2K1E0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

161398:PP2015 RS17270
gene id: 161398:PP2015_RS17270
uniprot id: A0A0S2K5T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

161398:PP2015 RS11655
gene id: 161398:PP2015_RS11655
uniprot id: A0A0S2K408
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

161398:PP2015 RS10690
gene id: 161398:PP2015_RS10690
uniprot id: A0A0S2K2U6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

161398:PP2015 RS17260
gene id: 161398:PP2015_RS17260
uniprot id: A0A0S2K6N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

161398:PP2015 RS04600
gene id: 161398:PP2015_RS04600
uniprot id: A0A0S2K035
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

161398:PP2015 RS13810
gene id: 161398:PP2015_RS13810
uniprot id: A0A0S2K553
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS08380
gene id: 161398:PP2015_RS08380
uniprot id: A0A0S2K299
names: Similarity
messages: Belongs to the asparaginase 1 family.

161398:PP2015 RS03240
gene id: 161398:PP2015_RS03240
uniprot id: A0A0S2JZA7
names: Similarity
messages: Belongs to the pirin family.

161398:PP2015 RS12930
gene id: 161398:PP2015_RS12930
uniprot id: A0A0S2K526
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

161398:PP2015 RS12675
gene id: 161398:PP2015_RS12675
uniprot id: A0A0S2K4K3
names: Subcellular Location Annotation
messages: Cytoplasm

161398:PP2015 RS13840
gene id: 161398:PP2015_RS13840
uniprot id: A0A0S2K4D7
names: Similarity
messages: Belongs to the UPF0246 family.

161398:PP2015 RS15605
gene id: 161398:PP2015_RS15605
uniprot id: A0A0S2K5K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

161398:PP2015 RS15225
gene id: 161398:PP2015_RS15225
uniprot id: A0A0S2K5Z0
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

161398:PP2015 RS20425
gene id: 161398:PP2015_RS20425
uniprot id: A0A0S2K8M4
names: Similarity
messages: Belongs to the PhzF family.

161398:PP2015 RS15655
gene id: 161398:PP2015_RS15655
uniprot id: A0A0S2K5D2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

161398:PP2015 RS05330
gene id: 161398:PP2015_RS05330
uniprot id: A0A0S2K073
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS14310
gene id: 161398:PP2015_RS14310
uniprot id: A0A0S2K5S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

161398:PP2015 RS03030
gene id: 161398:PP2015_RS03030
uniprot id: A0A0S2JYJ0
names: Similarity
messages: Belongs to the peptidase M24B family.

161398:PP2015 RS03060
gene id: 161398:PP2015_RS03060
uniprot id: A0A0S2JZF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

161398:PP2015 RS15985
gene id: 161398:PP2015_RS15985
uniprot id: A0A0S2K5R4
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

161398:PP2015 RS05035
gene id: 161398:PP2015_RS05035
uniprot id: A0A0S2JZK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

161398:PP2015 RS14220
gene id: 161398:PP2015_RS14220
uniprot id: A0A0S2K5R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

161398:PP2015 RS02590
gene id: 161398:PP2015_RS02590
uniprot id: A0A0S2JZ32
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

161398:PP2015 RS14470
gene id: 161398:PP2015_RS14470
uniprot id: A0A0S2K4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

161398:PP2015 RS07925
gene id: 161398:PP2015_RS07925
uniprot id: A0A0S2K193
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS03680
gene id: 161398:PP2015_RS03680
uniprot id: A0A0S2JYZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

161398:PP2015 RS16125
gene id: 161398:PP2015_RS16125
uniprot id: A0A0S2K5W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

161398:PP2015 RS02810
gene id: 161398:PP2015_RS02810
uniprot id: A0A0S2JZ38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

161398:PP2015 RS14295
gene id: 161398:PP2015_RS14295
uniprot id: A0A0S2K5E0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

161398:PP2015 RS05020
gene id: 161398:PP2015_RS05020
uniprot id: A0A0S2JZ97
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS00300
gene id: 161398:PP2015_RS00300
uniprot id: A0A0S2JX10
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

161398:PP2015 RS06160
gene id: 161398:PP2015_RS06160
uniprot id: A0A0S2JZT7
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS16095
gene id: 161398:PP2015_RS16095
uniprot id: A0A0S2K6E1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

161398:PP2015 RS21530
gene id: 161398:PP2015_RS21530
uniprot id: A0A0S2K932
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

161398:PP2015 RS04605
gene id: 161398:PP2015_RS04605
uniprot id: A0A0S2JZH9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

161398:PP2015 RS08605
gene id: 161398:PP2015_RS08605
uniprot id: A0A0S2K2L9
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS16255
gene id: 161398:PP2015_RS16255
uniprot id: A0A0S2K5H5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

161398:PP2015 RS20210
gene id: 161398:PP2015_RS20210
uniprot id: A0A0S2K7Z9
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

161398:PP2015 RS16915
gene id: 161398:PP2015_RS16915
uniprot id: A0A0S2K638
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

161398:PP2015 RS06310
gene id: 161398:PP2015_RS06310
uniprot id: A0A0S2JZV5
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

161398:PP2015 RS06500
gene id: 161398:PP2015_RS06500
uniprot id: A0A0S2K144
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

161398:PP2015 RS14930
gene id: 161398:PP2015_RS14930
uniprot id: A0A0S2K548
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

161398:PP2015 RS07825
gene id: 161398:PP2015_RS07825
uniprot id: A0A0S2K254
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS04830
gene id: 161398:PP2015_RS04830
uniprot id: A0A0S2K0A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS00245
gene id: 161398:PP2015_RS00245
uniprot id: A0A0S2JWU1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

161398:PP2015 RS13540
gene id: 161398:PP2015_RS13540
uniprot id: A0A0S2K4W8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

161398:PP2015 RS02025
gene id: 161398:PP2015_RS02025
uniprot id: A0A0S2JYT0
names: Similarity
messages: Belongs to the phosphoribulokinase family.

161398:PP2015 RS02470
gene id: 161398:PP2015_RS02470
uniprot id: A0A0S2JY58
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

161398:PP2015 RS12700
gene id: 161398:PP2015_RS12700
uniprot id: A0A0S2K4E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS06120
gene id: 161398:PP2015_RS06120
uniprot id: A0A0S2K151
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

161398:PP2015 RS02485
gene id: 161398:PP2015_RS02485
uniprot id: A0A0S2JZ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS02020
gene id: 161398:PP2015_RS02020
uniprot id: A0A0S2JYP8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

161398:PP2015 RS01195
gene id: 161398:PP2015_RS01195
uniprot id: A0A0S2JXR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

161398:PP2015 RS19460
gene id: 161398:PP2015_RS19460
uniprot id: A0A0S2K8E6
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

161398:PP2015 RS19980
gene id: 161398:PP2015_RS19980
uniprot id: A0A0S2K849
names: Similarity
messages: Belongs to the Nudix hydrolase family.

161398:PP2015 RS16235
gene id: 161398:PP2015_RS16235
uniprot id: A0A4Q7IM04
names: Caution
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS01255
gene id: 161398:PP2015_RS01255
uniprot id: A0A0S2JXP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

161398:PP2015 RS00015
gene id: 161398:PP2015_RS00015
uniprot id: A0A0S2JXE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

161398:PP2015 RS20860
gene id: 161398:PP2015_RS20860
uniprot id: A0A0S2K958
names: Similarity
messages: Belongs to the peptidase M17 family.

161398:PP2015 RS14935
gene id: 161398:PP2015_RS14935
uniprot id: A0A0S2K4I6
names: Similarity
messages: Belongs to the RutC family.

161398:PP2015 RS02545
gene id: 161398:PP2015_RS02545
uniprot id: A0A0S2JXZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

161398:PP2015 RS02245
gene id: 161398:PP2015_RS02245
uniprot id: A0A0S2JYS6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

161398:PP2015 RS01350
gene id: 161398:PP2015_RS01350
uniprot id: A0A0S2JY33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

161398:PP2015 RS01165
gene id: 161398:PP2015_RS01165
uniprot id: A0A0S2JXG7
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

161398:PP2015 RS10985
gene id: 161398:PP2015_RS10985
uniprot id: A0A0S2K314
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

161398:PP2015 RS21095
gene id: 161398:PP2015_RS21095
uniprot id: A0A0S2K8D5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

161398:PP2015 RS08005
gene id: 161398:PP2015_RS08005
uniprot id: A0A0S2K0N2
names: Similarity
messages: Belongs to the DapA family.

161398:PP2015 RS08495
gene id: 161398:PP2015_RS08495
uniprot id: A0A0S2K114
names: Similarity
messages: Belongs to the HIBADH-related family.

161398:PP2015 RS10535
gene id: 161398:PP2015_RS10535
uniprot id: A0A0S2K251
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

161398:PP2015 RS05435
gene id: 161398:PP2015_RS05435
uniprot id: A0A0S2JZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

161398:PP2015 RS14000
gene id: 161398:PP2015_RS14000
uniprot id: A0A0S2K4G8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

161398:PP2015 RS01260
gene id: 161398:PP2015_RS01260
uniprot id: A0A0S2JY23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

161398:PP2015 RS12140
gene id: 161398:PP2015_RS12140
uniprot id: A0A0S2K322
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161398:PP2015 RS01270
gene id: 161398:PP2015_RS01270
uniprot id: A0A0S2JXB4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

161398:PP2015 RS17070
gene id: 161398:PP2015_RS17070
uniprot id: A0A0S2K663
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

161398:PP2015 RS12680
gene id: 161398:PP2015_RS12680
uniprot id: A0A0S2K4L4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

161398:PP2015 RS00770
gene id: 161398:PP2015_RS00770
uniprot id: A0A0S2JXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

161398:PP2015 RS21505
gene id: 161398:PP2015_RS21505
uniprot id: A0A0S2K8N2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS02440
gene id: 161398:PP2015_RS02440
uniprot id: A0A0S2JYR7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

161398:PP2015 RS13340
gene id: 161398:PP2015_RS13340
uniprot id: A0A0S2K3Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

161398:PP2015 RS10440
gene id: 161398:PP2015_RS10440
uniprot id: A0A0S2K3C6
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS12210
gene id: 161398:PP2015_RS12210
uniprot id: A0A0S2K321
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS10120
gene id: 161398:PP2015_RS10120
uniprot id: A0A0S2K352
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

161398:PP2015 RS04850
gene id: 161398:PP2015_RS04850
uniprot id: A0A0S2JZ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

161398:PP2015 RS03500
gene id: 161398:PP2015_RS03500
uniprot id: A0A0S2JZ16
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

161398:PP2015 RS01640
gene id: 161398:PP2015_RS01640
uniprot id: A0A0S2JXX0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

161398:PP2015 RS13670
gene id: 161398:PP2015_RS13670
uniprot id: A0A0S2K4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

161398:PP2015 RS14705
gene id: 161398:PP2015_RS14705
uniprot id: A0A0S2K4Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

161398:PP2015 RS02915
gene id: 161398:PP2015_RS02915
uniprot id: A0A0S2JZ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

161398:PP2015 RS13645
gene id: 161398:PP2015_RS13645
uniprot id: A0A0S2K523
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

161398:PP2015 RS07905
gene id: 161398:PP2015_RS07905
uniprot id: A0A0S2K270
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS16195
gene id: 161398:PP2015_RS16195
uniprot id: A0A0S2K5T4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

161398:PP2015 RS16260
gene id: 161398:PP2015_RS16260
uniprot id: A0A0S2K5P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

161398:PP2015 RS02535
gene id: 161398:PP2015_RS02535
uniprot id: A0A0S2JYA2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS16160
gene id: 161398:PP2015_RS16160
uniprot id: A0A0S2K6L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

161398:PP2015 RS10080
gene id: 161398:PP2015_RS10080
uniprot id: A0A0S2K1V7
names: Similarity
messages: Belongs to the UPF0352 family.

161398:PP2015 RS07665
gene id: 161398:PP2015_RS07665
uniprot id: A0A0S2K1V5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS21220
gene id: 161398:PP2015_RS21220
uniprot id: A0A0S2K8S3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

161398:PP2015 RS20500
gene id: 161398:PP2015_RS20500
uniprot id: A0A0S2K887
names: Similarity
messages: Belongs to the YjdM family.

161398:PP2015 RS05800
gene id: 161398:PP2015_RS05800
uniprot id: A0A0S2JZX1
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS03670
gene id: 161398:PP2015_RS03670
uniprot id: A0A0S2JYK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

161398:PP2015 RS02540
gene id: 161398:PP2015_RS02540
uniprot id: A0A0S2JYA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

161398:PP2015 RS20310
gene id: 161398:PP2015_RS20310
uniprot id: A0A0S2K8A3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

161398:PP2015 RS03985
gene id: 161398:PP2015_RS03985
uniprot id: A0A0S2JZR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

161398:PP2015 RS09800
gene id: 161398:PP2015_RS09800
uniprot id: A0A0S2K203
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

161398:PP2015 RS04355
gene id: 161398:PP2015_RS04355
uniprot id: A0A0S2JZ68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

161398:PP2015 RS01870
gene id: 161398:PP2015_RS01870
uniprot id: A0A0S2JYE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

161398:PP2015 RS10590
gene id: 161398:PP2015_RS10590
uniprot id: A0A0S2K2T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS14675
gene id: 161398:PP2015_RS14675
uniprot id: A0A0S2K4F5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS19180
gene id: 161398:PP2015_RS19180
uniprot id: A0A0S2K793
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

161398:PP2015 RS07890
gene id: 161398:PP2015_RS07890
uniprot id: A0A0S2K1W0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

161398:PP2015 RS04425
gene id: 161398:PP2015_RS04425
uniprot id: A0A0S2JZB5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

161398:PP2015 RS11220
gene id: 161398:PP2015_RS11220
uniprot id: A0A0S2K2U4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

161398:PP2015 RS14505
gene id: 161398:PP2015_RS14505
uniprot id: A0A0S2K5A9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

161398:PP2015 RS15580
gene id: 161398:PP2015_RS15580
uniprot id: A0A0S2K5W8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

161398:PP2015 RS07270
gene id: 161398:PP2015_RS07270
uniprot id: A0A0S2K1I6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS05010
gene id: 161398:PP2015_RS05010
uniprot id: A0A0S2JZX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS08070
gene id: 161398:PP2015_RS08070
uniprot id: A0A0S2K1Z5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

161398:PP2015 RS11610
gene id: 161398:PP2015_RS11610
uniprot id: A0A0S2K399
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS00855
gene id: 161398:PP2015_RS00855
uniprot id: A0A0S2JXK3
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

161398:PP2015 RS13145
gene id: 161398:PP2015_RS13145
uniprot id: A0A0S2K4A6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

161398:PP2015 RS13405
gene id: 161398:PP2015_RS13405
uniprot id: A0A0S2K4V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

161398:PP2015 RS16285
gene id: 161398:PP2015_RS16285
uniprot id: A0A0S2K5V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

161398:PP2015 RS16740
gene id: 161398:PP2015_RS16740
uniprot id: A0A0S2K6Y1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

161398:PP2015 RS14055
gene id: 161398:PP2015_RS14055
uniprot id: A0A0S2K4P1
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

161398:PP2015 RS02610
gene id: 161398:PP2015_RS02610
uniprot id: A0A0S2JY03
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS05185
gene id: 161398:PP2015_RS05185
uniprot id: A0A0S2JZU2
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS15455
gene id: 161398:PP2015_RS15455
uniprot id: A0A0S2K6B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

161398:PP2015 RS14595
gene id: 161398:PP2015_RS14595
uniprot id: A0A0S2K4D8
names: Similarity
messages: Belongs to the YicC/YloC family.

161398:PP2015 RS21160
gene id: 161398:PP2015_RS21160
uniprot id: A0A0S2K8E4
names: Similarity
messages: Belongs to the GST superfamily.

161398:PP2015 RS13625
gene id: 161398:PP2015_RS13625
uniprot id: A0A0S2K509
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

161398:PP2015 RS04840
gene id: 161398:PP2015_RS04840
uniprot id: A0A0S2K078
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

161398:PP2015 RS15385
gene id: 161398:PP2015_RS15385
uniprot id: A0A0S2K626
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

161398:PP2015 RS14400
gene id: 161398:PP2015_RS14400
uniprot id: A0A0S2K5I8
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS20420
gene id: 161398:PP2015_RS20420
uniprot id: A0A0S2K855
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS06150
gene id: 161398:PP2015_RS06150
uniprot id: A0A0S2K0Q4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS03890
gene id: 161398:PP2015_RS03890
uniprot id: A0A0S2JZ53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

161398:PP2015 RS07770
gene id: 161398:PP2015_RS07770
uniprot id: A0A0S2K1M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

161398:PP2015 RS08540
gene id: 161398:PP2015_RS08540
uniprot id: A0A0S2K2C4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

161398:PP2015 RS08770
gene id: 161398:PP2015_RS08770
uniprot id: A0A0S2K2H4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS15750
gene id: 161398:PP2015_RS15750
uniprot id: A0A0S2K5F0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS06570
gene id: 161398:PP2015_RS06570
uniprot id: A0A0S2K0G6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS13985
gene id: 161398:PP2015_RS13985
uniprot id: A0A0S2K506
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

161398:PP2015 RS14260
gene id: 161398:PP2015_RS14260
uniprot id: A0A0S2K4Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

161398:PP2015 RS17295
gene id: 161398:PP2015_RS17295
uniprot id: A0A0S2K794
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

161398:PP2015 RS15085
gene id: 161398:PP2015_RS15085
uniprot id: A0A0S2K580
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS11230
gene id: 161398:PP2015_RS11230
uniprot id: A0A0S2K440
names: Similarity
messages: Belongs to the MipA/OmpV family.

161398:PP2015 RS09745
gene id: 161398:PP2015_RS09745
uniprot id: A0A0S2K2X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

161398:PP2015 RS13740
gene id: 161398:PP2015_RS13740
uniprot id: A0A0S2K3V1
names: Similarity
messages: Belongs to the threonine synthase family.

161398:PP2015 RS12770
gene id: 161398:PP2015_RS12770
uniprot id: A0A0S2K402
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

161398:PP2015 RS02850
gene id: 161398:PP2015_RS02850
uniprot id: A0A0S2JY55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

161398:PP2015 RS09870
gene id: 161398:PP2015_RS09870
uniprot id: A0A5S3YQ40
names: Caution
names: Similarity
messages: Belongs to the glutathione peroxidase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS12420
gene id: 161398:PP2015_RS12420
uniprot id: A0A0S2K4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

161398:PP2015 RS14110
gene id: 161398:PP2015_RS14110
uniprot id: A0A0S2K4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS19360
gene id: 161398:PP2015_RS19360
uniprot id: A0A0S2K839
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

161398:PP2015 RS02005
gene id: 161398:PP2015_RS02005
uniprot id: A0A0S2JYP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

161398:PP2015 RS20235
gene id: 161398:PP2015_RS20235
uniprot id: A0A0S2K7Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS03360
gene id: 161398:PP2015_RS03360
uniprot id: A0A0S2JYF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS19450
gene id: 161398:PP2015_RS19450
uniprot id: A0A0S2K7P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

161398:PP2015 RS05305
gene id: 161398:PP2015_RS05305
uniprot id: A0A0S2K0E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

161398:PP2015 RS02160
gene id: 161398:PP2015_RS02160
uniprot id: A0A0S2JY36
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

161398:PP2015 RS01325
gene id: 161398:PP2015_RS01325
uniprot id: A0A0S2JXK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

161398:PP2015 RS08620
gene id: 161398:PP2015_RS08620
uniprot id: A0A0S2K2C1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS14020
gene id: 161398:PP2015_RS14020
uniprot id: A0A0S2K5A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

161398:PP2015 RS15780
gene id: 161398:PP2015_RS15780
uniprot id: A0A0S2K4Y9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

161398:PP2015 RS10525
gene id: 161398:PP2015_RS10525
uniprot id: A0A0S2K3E4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS20945
gene id: 161398:PP2015_RS20945
uniprot id: A0A0S2K987
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS15945
gene id: 161398:PP2015_RS15945
uniprot id: A0A0S2K684
names: Similarity
messages: Belongs to the HSP15 family.

161398:PP2015 RS12590
gene id: 161398:PP2015_RS12590
uniprot id: A0A0S2K4I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

161398:PP2015 RS14105
gene id: 161398:PP2015_RS14105
uniprot id: A0A0S2K4E8
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

161398:PP2015 RS03065
gene id: 161398:PP2015_RS03065
uniprot id: A0A0S2JZ77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

161398:PP2015 RS17830
gene id: 161398:PP2015_RS17830
uniprot id: A0A0S2K6Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

161398:PP2015 RS01225
gene id: 161398:PP2015_RS01225
uniprot id: A0A0S2JX88
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

161398:PP2015 RS09495
gene id: 161398:PP2015_RS09495
uniprot id: A0A0S2K2T7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

161398:PP2015 RS20830
gene id: 161398:PP2015_RS20830
uniprot id: A0A0S2K8E8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

161398:PP2015 RS10275
gene id: 161398:PP2015_RS10275
uniprot id: A0A0S2K2N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS05320
gene id: 161398:PP2015_RS05320
uniprot id: A0A0S2K0M1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

161398:PP2015 RS10145
gene id: 161398:PP2015_RS10145
uniprot id: A0A0S2K351
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

161398:PP2015 RS10020
gene id: 161398:PP2015_RS10020
uniprot id: A0A0S2K2A6
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

161398:PP2015 RS17840
gene id: 161398:PP2015_RS17840
uniprot id: A0A0S2K671
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

161398:PP2015 RS00050
gene id: 161398:PP2015_RS00050
uniprot id: A0A0S2JWV1
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

161398:PP2015 RS17785
gene id: 161398:PP2015_RS17785
uniprot id: A0A0S2K7J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

161398:PP2015 RS03375
gene id: 161398:PP2015_RS03375
uniprot id: A0A0S2JYQ2
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS08610
gene id: 161398:PP2015_RS08610
uniprot id: A0A0S2K2E7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS20605
gene id: 161398:PP2015_RS20605
uniprot id: A0A0S2K864
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS11960
gene id: 161398:PP2015_RS11960
uniprot id: A0A0S2K3J0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

161398:PP2015 RS09335
gene id: 161398:PP2015_RS09335
uniprot id: A0A0S2K2Q3
names: Similarity
messages: Belongs to the peptidase S49 family.

161398:PP2015 RS09755
gene id: 161398:PP2015_RS09755
uniprot id: A0A0S2K1N8
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

161398:PP2015 RS04590
gene id: 161398:PP2015_RS04590
uniprot id: A0A0S2K060
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

161398:PP2015 RS11695
gene id: 161398:PP2015_RS11695
uniprot id: A0A0S2K396
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

161398:PP2015 RS02775
gene id: 161398:PP2015_RS02775
uniprot id: A0A0S2JYE7
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

161398:PP2015 RS12155
gene id: 161398:PP2015_RS12155
uniprot id: A0A0S2K3S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

161398:PP2015 RS08830
gene id: 161398:PP2015_RS08830
uniprot id: A0A0S2K1H1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

161398:PP2015 RS15585
gene id: 161398:PP2015_RS15585
uniprot id: A0A0S2K5L5
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS01660
gene id: 161398:PP2015_RS01660
uniprot id: A0A0S2JXJ2
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

161398:PP2015 RS04810
gene id: 161398:PP2015_RS04810
uniprot id: A0A0S2K071
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

161398:PP2015 RS09455
gene id: 161398:PP2015_RS09455
uniprot id: A0A0S2K246
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

161398:PP2015 RS15330
gene id: 161398:PP2015_RS15330
uniprot id: A0A0S2K5G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

161398:PP2015 RS20685
gene id: 161398:PP2015_RS20685
uniprot id: A0A0S2K877
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

161398:PP2015 RS10710
gene id: 161398:PP2015_RS10710
uniprot id: A0A0S2K292
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

161398:PP2015 RS12795
gene id: 161398:PP2015_RS12795
uniprot id: A0A0S2K3W9
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS12280
gene id: 161398:PP2015_RS12280
uniprot id: A0A0S2K3Q5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

161398:PP2015 RS08560
gene id: 161398:PP2015_RS08560
uniprot id: A0A0S2K0Z8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

161398:PP2015 RS10510
gene id: 161398:PP2015_RS10510
uniprot id: A0A0S2K3P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

161398:PP2015 RS15920
gene id: 161398:PP2015_RS15920
uniprot id: A0A0S2K5A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS01050
gene id: 161398:PP2015_RS01050
uniprot id: A0A0S2JX62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

161398:PP2015 RS02820
gene id: 161398:PP2015_RS02820
uniprot id: A0A0S2JYK6
names: Similarity
messages: Belongs to the SfsA family.

161398:PP2015 RS14690
gene id: 161398:PP2015_RS14690
uniprot id: A0A0S2K534
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

161398:PP2015 RS13435
gene id: 161398:PP2015_RS13435
uniprot id: A0A0S2K4Z6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

161398:PP2015 RS06495
gene id: 161398:PP2015_RS06495
uniprot id: A0A0S2K154
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

161398:PP2015 RS08250
gene id: 161398:PP2015_RS08250
uniprot id: A0A0S2K0S5
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS05155
gene id: 161398:PP2015_RS05155
uniprot id: A0A0S2K0F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS01230
gene id: 161398:PP2015_RS01230
uniprot id: A0A0S2JXL1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

161398:PP2015 RS17890
gene id: 161398:PP2015_RS17890
uniprot id: A0A0S2K7G2
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

161398:PP2015 RS04995
gene id: 161398:PP2015_RS04995
uniprot id: A0A0S2K016
names: Similarity
messages: Belongs to the MlaA family.

161398:PP2015 RS15675
gene id: 161398:PP2015_RS15675
uniprot id: A0A0S2K656
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

161398:PP2015 RS16585
gene id: 161398:PP2015_RS16585
uniprot id: A0A0S2K5V5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

161398:PP2015 RS21460
gene id: 161398:PP2015_RS21460
uniprot id: A0A0S2K8V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

161398:PP2015 RS15535
gene id: 161398:PP2015_RS15535
uniprot id: A0A0S2K661
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

161398:PP2015 RS07870
gene id: 161398:PP2015_RS07870
uniprot id: A0A0S2K181
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

161398:PP2015 RS17585
gene id: 161398:PP2015_RS17585
uniprot id: A0A0S2K6U5
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS03295
gene id: 161398:PP2015_RS03295
uniprot id: A0A0S2JYP2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

161398:PP2015 RS08520
gene id: 161398:PP2015_RS08520
uniprot id: A0A0S2K293
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

161398:PP2015 RS05635
gene id: 161398:PP2015_RS05635
uniprot id: A0A0S2K0K2
names: Similarity
messages: Belongs to the isochorismate synthase family.

161398:PP2015 RS01655
gene id: 161398:PP2015_RS01655
uniprot id: A0A0S2JXU0
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

161398:PP2015 RS17780
gene id: 161398:PP2015_RS17780
uniprot id: A0A0S2K779
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161398:PP2015 RS14095
gene id: 161398:PP2015_RS14095
uniprot id: A0A0S2K5A2
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

161398:PP2015 RS14795
gene id: 161398:PP2015_RS14795
uniprot id: A0A0S2K4V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

161398:PP2015 RS20240
gene id: 161398:PP2015_RS20240
uniprot id: A0A0S2K7T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

161398:PP2015 RS09150
gene id: 161398:PP2015_RS09150
uniprot id: A0A0S2K1X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

161398:PP2015 RS01515
gene id: 161398:PP2015_RS01515
uniprot id: A0A0S2JXS5
names: Similarity
messages: Belongs to the peptidase U62 family.

161398:PP2015 RS10880
gene id: 161398:PP2015_RS10880
uniprot id: A0A0S2K2T3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS20400
gene id: 161398:PP2015_RS20400
uniprot id: A0A0S2K7U0
names: Similarity
messages: Belongs to the Gfa family.

161398:PP2015 RS10075
gene id: 161398:PP2015_RS10075
uniprot id: A0A0S2K2G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

161398:PP2015 RS13715
gene id: 161398:PP2015_RS13715
uniprot id: A0A0S2K5F6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

161398:PP2015 RS10755
gene id: 161398:PP2015_RS10755
uniprot id: A0A0S2K3I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

161398:PP2015 RS12580
gene id: 161398:PP2015_RS12580
uniprot id: A0A0S2K3V0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

161398:PP2015 RS00490
gene id: 161398:PP2015_RS00490
uniprot id: A0A0S2JWY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

161398:PP2015 RS14395
gene id: 161398:PP2015_RS14395
uniprot id: A0A0S2K5I4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

161398:PP2015 RS16955
gene id: 161398:PP2015_RS16955
uniprot id: A0A0S2K6F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS12625
gene id: 161398:PP2015_RS12625
uniprot id: A0A0S2K433
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

161398:PP2015 RS14340
gene id: 161398:PP2015_RS14340
uniprot id: A0A0S2K578
names: Similarity
messages: Belongs to the GARS family.

161398:PP2015 RS02510
gene id: 161398:PP2015_RS02510
uniprot id: A0A0S2JZ19
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS01220
gene id: 161398:PP2015_RS01220
uniprot id: A0A0S2JXQ9
names: Similarity
messages: Belongs to the peptidase U62 family.

161398:PP2015 RS20250
gene id: 161398:PP2015_RS20250
uniprot id: A0A0S2K8J3
names: Similarity
messages: Belongs to the Gfa family.

161398:PP2015 RS02615
gene id: 161398:PP2015_RS02615
uniprot id: A0A0S2JYB7
names: Similarity
messages: Belongs to the YfgM family.

161398:PP2015 RS12865
gene id: 161398:PP2015_RS12865
uniprot id: A0A0S2K479
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

161398:PP2015 RS02940
gene id: 161398:PP2015_RS02940
uniprot id: A0A0S2JYH4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

161398:PP2015 RS01045
gene id: 161398:PP2015_RS01045
uniprot id: A0A0S2JXN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

161398:PP2015 RS10265
gene id: 161398:PP2015_RS10265
uniprot id: A0A0S2K388
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

161398:PP2015 RS10775
gene id: 161398:PP2015_RS10775
uniprot id: A0A0S2K2A4
names: Similarity
messages: Belongs to the nitroreductase family.

161398:PP2015 RS02040
gene id: 161398:PP2015_RS02040
uniprot id: A0A0S2JY56
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

161398:PP2015 RS04185
gene id: 161398:PP2015_RS04185
uniprot id: A0A0S2JYT9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS16210
gene id: 161398:PP2015_RS16210
uniprot id: A0A0S2K5X6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

161398:PP2015 RS03555
gene id: 161398:PP2015_RS03555
uniprot id: A0A0S2JYX6
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

161398:PP2015 RS15265
gene id: 161398:PP2015_RS15265
uniprot id: A0A0S2K574
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

161398:PP2015 RS13570
gene id: 161398:PP2015_RS13570
uniprot id: A0A0S2K512
names: Similarity
messages: Belongs to the peptidase S16 family.

161398:PP2015 RS07760
gene id: 161398:PP2015_RS07760
uniprot id: A0A0S2K155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

161398:PP2015 RS01610
gene id: 161398:PP2015_RS01610
uniprot id: A0A0S2JXI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS04195
gene id: 161398:PP2015_RS04195
uniprot id: A0A0S2JZA5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161398:PP2015 RS02910
gene id: 161398:PP2015_RS02910
uniprot id: A0A0S2JZ60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

161398:PP2015 RS16350
gene id: 161398:PP2015_RS16350
uniprot id: A0A0S2K6I8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

161398:PP2015 RS16515
gene id: 161398:PP2015_RS16515
uniprot id: A0A0S2K6N2
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS07485
gene id: 161398:PP2015_RS07485
uniprot id: A0A0S2K1N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

161398:PP2015 RS20000
gene id: 161398:PP2015_RS20000
uniprot id: A0A0S2K7Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

161398:PP2015 RS12505
gene id: 161398:PP2015_RS12505
uniprot id: A0A0S2K4H2
names: Subcellular Location Annotation
messages: Cytoplasm

161398:PP2015 RS02155
gene id: 161398:PP2015_RS02155
uniprot id: A0A0S2JY32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS13735
gene id: 161398:PP2015_RS13735
uniprot id: A0A0S2K4F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS09035
gene id: 161398:PP2015_RS09035
uniprot id: A0A0S2K1X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

161398:PP2015 RS21535
gene id: 161398:PP2015_RS21535
uniprot id: A0A0S2K8M1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

161398:PP2015 RS09655
gene id: 161398:PP2015_RS09655
uniprot id: A0A0S2K2D7
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

161398:PP2015 RS01875
gene id: 161398:PP2015_RS01875
uniprot id: A0A0S2JYJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

161398:PP2015 RS10745
gene id: 161398:PP2015_RS10745
uniprot id: A0A0S2K2W7
names: Similarity
messages: Belongs to the PhzF family.

161398:PP2015 RS06705
gene id: 161398:PP2015_RS06705
uniprot id: A0A0S2K110
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

161398:PP2015 RS13630
gene id: 161398:PP2015_RS13630
uniprot id: A0A0S2K434
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

161398:PP2015 RS16610
gene id: 161398:PP2015_RS16610
uniprot id: A0A0S2K620
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

161398:PP2015 RS08900
gene id: 161398:PP2015_RS08900
uniprot id: A0A0S2K2H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

161398:PP2015 RS00185
gene id: 161398:PP2015_RS00185
uniprot id: A0A0S2JXJ1
names: Similarity
messages: Belongs to the peptidase S8 family.

161398:PP2015 RS18125
gene id: 161398:PP2015_RS18125
uniprot id: A0A0S2K6R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

161398:PP2015 RS11730
gene id: 161398:PP2015_RS11730
uniprot id: A0A0S2K427
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

161398:PP2015 RS15800
gene id: 161398:PP2015_RS15800
uniprot id: A0A0S2K5F7
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

161398:PP2015 RS13610
gene id: 161398:PP2015_RS13610
uniprot id: A0A5R9Q484
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS13410
gene id: 161398:PP2015_RS13410
uniprot id: A0A0S2K4X7
names: Similarity
messages: Belongs to the UPF0162 family.

161398:PP2015 RS06385
gene id: 161398:PP2015_RS06385
uniprot id: A0A0S2K156
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS08445
gene id: 161398:PP2015_RS08445
uniprot id: A0A0S2K1A2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS01650
gene id: 161398:PP2015_RS01650
uniprot id: A0A0S2JXS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

161398:PP2015 RS00725
gene id: 161398:PP2015_RS00725
uniprot id: A0A0S2JXC6
names: Similarity
messages: Belongs to the UPF0319 family.

161398:PP2015 RS02865
gene id: 161398:PP2015_RS02865
uniprot id: A0A0S2JY60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

161398:PP2015 RS18290
gene id: 161398:PP2015_RS18290
uniprot id: A0A0S2K6H2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

161398:PP2015 RS15460
gene id: 161398:PP2015_RS15460
uniprot id: A0A0S2K648
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

161398:PP2015 RS06075
gene id: 161398:PP2015_RS06075
uniprot id: A0A0S2K0I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

161398:PP2015 RS00745
gene id: 161398:PP2015_RS00745
uniprot id: A0A0S2JXE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS12870
gene id: 161398:PP2015_RS12870
uniprot id: A0A0S2K3H0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

161398:PP2015 RS11115
gene id: 161398:PP2015_RS11115
uniprot id: A0A0S2K303
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS07955
gene id: 161398:PP2015_RS07955
uniprot id: A0A0S2K180
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

161398:PP2015 RS21415
gene id: 161398:PP2015_RS21415
uniprot id: A0A0S2K9L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

161398:PP2015 RS12850
gene id: 161398:PP2015_RS12850
uniprot id: A0A0S2K410
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

161398:PP2015 RS09945
gene id: 161398:PP2015_RS09945
uniprot id: A0A0S2K2I5
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

161398:PP2015 RS14070
gene id: 161398:PP2015_RS14070
uniprot id: A0A0S2K4U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

161398:PP2015 RS12425
gene id: 161398:PP2015_RS12425
uniprot id: A0A0S2K4G0
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

161398:PP2015 RS18840
gene id: 161398:PP2015_RS18840
uniprot id: A0A0S2K769
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

161398:PP2015 RS20070
gene id: 161398:PP2015_RS20070
uniprot id: A0A5R9Q2Z0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS07010
gene id: 161398:PP2015_RS07010
uniprot id: A0A0S2K0Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

161398:PP2015 RS10875
gene id: 161398:PP2015_RS10875
uniprot id: A0A0S2K2W1
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS02800
gene id: 161398:PP2015_RS02800
uniprot id: A0A0S2JYF1
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

161398:PP2015 RS10095
gene id: 161398:PP2015_RS10095
uniprot id: A0A0S2K1W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

161398:PP2015 RS09525
gene id: 161398:PP2015_RS09525
uniprot id: A0A0S2K2U5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

161398:PP2015 RS10695
gene id: 161398:PP2015_RS10695
uniprot id: A0A0S2K278
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

161398:PP2015 RS15890
gene id: 161398:PP2015_RS15890
uniprot id: A0A0S2K513
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

161398:PP2015 RS17820
gene id: 161398:PP2015_RS17820
uniprot id: A0A0S2K6K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

161398:PP2015 RS09125
gene id: 161398:PP2015_RS09125
uniprot id: A0A0S2K1Y7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

161398:PP2015 RS00040
gene id: 161398:PP2015_RS00040
uniprot id: A0A0S2JWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

161398:PP2015 RS01290
gene id: 161398:PP2015_RS01290
uniprot id: A0A0S2JY37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

161398:PP2015 RS01965
gene id: 161398:PP2015_RS01965
uniprot id: A0A0S2JXP7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

161398:PP2015 RS11075
gene id: 161398:PP2015_RS11075
uniprot id: A0A0S2K3P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS15515
gene id: 161398:PP2015_RS15515
uniprot id: A0A0S2K595
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

161398:PP2015 RS12445
gene id: 161398:PP2015_RS12445
uniprot id: A0A0S2K373
names: Similarity
messages: Belongs to the GSP E family.

161398:PP2015 RS01690
gene id: 161398:PP2015_RS01690
uniprot id: A0A0S2JXJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

161398:PP2015 RS12635
gene id: 161398:PP2015_RS12635
uniprot id: A0A0S2K3U1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

161398:PP2015 RS20050
gene id: 161398:PP2015_RS20050
uniprot id: A0A0S2K7L7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

161398:PP2015 RS02985
gene id: 161398:PP2015_RS02985
uniprot id: A0A0S2JZ65
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

161398:PP2015 RS01080
gene id: 161398:PP2015_RS01080
uniprot id: A0A0S2JX87
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

161398:PP2015 RS13050
gene id: 161398:PP2015_RS13050
uniprot id: A0A0S2K3K3
names: Similarity
messages: Belongs to the peptidase M16 family.

161398:PP2015 RS05395
gene id: 161398:PP2015_RS05395
uniprot id: A0A0S2K0N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS07595
gene id: 161398:PP2015_RS07595
uniprot id: A0A0S2K1Q0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

161398:PP2015 RS19875
gene id: 161398:PP2015_RS19875
uniprot id: A0A0S2K878
names: Subcellular Location Annotation
messages: Secreted

161398:PP2015 RS22030
gene id: 161398:PP2015_RS22030
uniprot id: A0A0S2K0W2
names: Similarity
messages: Belongs to the peptidase S8 family.

161398:PP2015 RS15250
gene id: 161398:PP2015_RS15250
uniprot id: A0A0S2K5Q5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

161398:PP2015 RS00095
gene id: 161398:PP2015_RS00095
uniprot id: A0A0S2JXG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

161398:PP2015 RS03825
gene id: 161398:PP2015_RS03825
uniprot id: A0A0S2JZ70
names: Similarity
messages: Belongs to the DEAD box helicase family.

161398:PP2015 RS14290
gene id: 161398:PP2015_RS14290
uniprot id: A0A0S2K5D1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

161398:PP2015 RS01805
gene id: 161398:PP2015_RS01805
uniprot id: A0A0S2JXK7
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS06520
gene id: 161398:PP2015_RS06520
uniprot id: A0A0S2K186
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

161398:PP2015 RS02045
gene id: 161398:PP2015_RS02045
uniprot id: A0A0S2JXR0
names: Similarity
messages: Belongs to the PspA/IM30 family.

161398:PP2015 RS15300
gene id: 161398:PP2015_RS15300
uniprot id: A0A0S2K613
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

161398:PP2015 RS10160
gene id: 161398:PP2015_RS10160
uniprot id: A0A0S2K1X2
names: Similarity
messages: Belongs to the peptidase M13 family.

161398:PP2015 RS09935
gene id: 161398:PP2015_RS09935
uniprot id: A0A0S2K296
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

161398:PP2015 RS10585
gene id: 161398:PP2015_RS10585
uniprot id: A0A0S2K2F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

161398:PP2015 RS03730
gene id: 161398:PP2015_RS03730
uniprot id: A0A0S2JZQ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS04975
gene id: 161398:PP2015_RS04975
uniprot id: A0A0S2JZC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS21155
gene id: 161398:PP2015_RS21155
uniprot id: A0A0S2K8F2
names: Similarity
messages: Belongs to the DEAD box helicase family.

161398:PP2015 RS15360
gene id: 161398:PP2015_RS15360
uniprot id: A0A0S2K609
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

161398:PP2015 RS15010
gene id: 161398:PP2015_RS15010
uniprot id: A0A0S2K563
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

161398:PP2015 RS08110
gene id: 161398:PP2015_RS08110
uniprot id: A0A0S2K1B5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

161398:PP2015 RS00110
gene id: 161398:PP2015_RS00110
uniprot id: A0A0S2JX15
names: Similarity
messages: Belongs to the Smg family.

161398:PP2015 RS10960
gene id: 161398:PP2015_RS10960
uniprot id: A0A0S2K2U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

161398:PP2015 RS08425
gene id: 161398:PP2015_RS08425
uniprot id: A0A0S2K1H9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

161398:PP2015 RS05080
gene id: 161398:PP2015_RS05080
uniprot id: A0A0S2JZQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

161398:PP2015 RS17140
gene id: 161398:PP2015_RS17140
uniprot id: A0A0S2K757
names: Similarity
messages: Belongs to the DinB family.

161398:PP2015 RS07880
gene id: 161398:PP2015_RS07880
uniprot id: A0A0S2K1B7
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

161398:PP2015 RS02290
gene id: 161398:PP2015_RS02290
uniprot id: A0A0S2JY44
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

161398:PP2015 RS14465
gene id: 161398:PP2015_RS14465
uniprot id: A0A0S2K4K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

161398:PP2015 RS15685
gene id: 161398:PP2015_RS15685
uniprot id: A0A0S2K4X1
names: Similarity
messages: Belongs to the leucine-binding protein family.

161398:PP2015 RS15795
gene id: 161398:PP2015_RS15795
uniprot id: A0A0S2K4Z7
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS21475
gene id: 161398:PP2015_RS21475
uniprot id: A0A5R9Q4W2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS01235
gene id: 161398:PP2015_RS01235
uniprot id: A0A0S2JXM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

161398:PP2015 RS10380
gene id: 161398:PP2015_RS10380
uniprot id: A0A0S2K216
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

161398:PP2015 RS01960
gene id: 161398:PP2015_RS01960
uniprot id: A0A0S2JY39
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

161398:PP2015 RS00975
gene id: 161398:PP2015_RS00975
uniprot id: A0A0S2JXI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

161398:PP2015 RS02390
gene id: 161398:PP2015_RS02390
uniprot id: A0A0S2JY41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

161398:PP2015 RS10900
gene id: 161398:PP2015_RS10900
uniprot id: A0A0S2K2M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS03630
gene id: 161398:PP2015_RS03630
uniprot id: A0A0S2JZK5
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

161398:PP2015 RS03390
gene id: 161398:PP2015_RS03390
uniprot id: A0A0S2JYF8
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS07515
gene id: 161398:PP2015_RS07515
uniprot id: A0A0S2K1N6
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

161398:PP2015 RS12775
gene id: 161398:PP2015_RS12775
uniprot id: A0A0S2K3D9
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

161398:PP2015 RS00555
gene id: 161398:PP2015_RS00555
uniprot id: A0A0S2JXE0
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

161398:PP2015 RS02755
gene id: 161398:PP2015_RS02755
uniprot id: A0A0S2JYU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS00840
gene id: 161398:PP2015_RS00840
uniprot id: A0A0S2JXP1
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

161398:PP2015 RS00385
gene id: 161398:PP2015_RS00385
uniprot id: A0A0S2JX09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

161398:PP2015 RS12360
gene id: 161398:PP2015_RS12360
uniprot id: A0A0S2K3S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

161398:PP2015 RS12660
gene id: 161398:PP2015_RS12660
uniprot id: A0A0S2K3L5
names: Similarity
messages: Belongs to the SUI1 family.

161398:PP2015 RS10905
gene id: 161398:PP2015_RS10905
uniprot id: A0A0S2K2Z9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

161398:PP2015 RS07135
gene id: 161398:PP2015_RS07135
uniprot id: A0A0S2K0U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS04500
gene id: 161398:PP2015_RS04500
uniprot id: A0A0S2JZM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

161398:PP2015 RS16150
gene id: 161398:PP2015_RS16150
uniprot id: A0A0S2K5U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

161398:PP2015 RS17290
gene id: 161398:PP2015_RS17290
uniprot id: A0A0S2K6X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

161398:PP2015 RS04290
gene id: 161398:PP2015_RS04290
uniprot id: A0A0S2JZX7
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

161398:PP2015 RS15940
gene id: 161398:PP2015_RS15940
uniprot id: A0A0S2K6A0
names: Similarity
messages: Belongs to the GSP C family.

161398:PP2015 RS03100
gene id: 161398:PP2015_RS03100
uniprot id: A0A0S2JYT8
names: Similarity
messages: Belongs to the peptidase M16 family.

161398:PP2015 RS14560
gene id: 161398:PP2015_RS14560
uniprot id: A0A0S2K5L4
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

161398:PP2015 RS07455
gene id: 161398:PP2015_RS07455
uniprot id: A0A0S2K191
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

161398:PP2015 RS07950
gene id: 161398:PP2015_RS07950
uniprot id: A0A0S2K194
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

161398:PP2015 RS06155
gene id: 161398:PP2015_RS06155
uniprot id: A0A0S2K0K6
names: Similarity
messages: Belongs to the pirin family.

161398:PP2015 RS19520
gene id: 161398:PP2015_RS19520
uniprot id: A0A0S2K8J2
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS11255
gene id: 161398:PP2015_RS11255
uniprot id: A0A0S2K2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS10325
gene id: 161398:PP2015_RS10325
uniprot id: A0A0S2K2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

161398:PP2015 RS06575
gene id: 161398:PP2015_RS06575
uniprot id: A0A0S2K0L2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

161398:PP2015 RS10100
gene id: 161398:PP2015_RS10100
uniprot id: A0A0S2K2E3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS09825
gene id: 161398:PP2015_RS09825
uniprot id: A0A0S2K2Z5
names: Similarity
messages: Belongs to the ArsC family.

161398:PP2015 RS17310
gene id: 161398:PP2015_RS17310
uniprot id: A0A0S2K7B6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS08220
gene id: 161398:PP2015_RS08220
uniprot id: A0A0S2K1K2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

161398:PP2015 RS20495
gene id: 161398:PP2015_RS20495
uniprot id: A0A0S2K7X9
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

161398:PP2015 RS11795
gene id: 161398:PP2015_RS11795
uniprot id: A0A0S2K359
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS21230
gene id: 161398:PP2015_RS21230
uniprot id: A0A0S2K8F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

161398:PP2015 RS12460
gene id: 161398:PP2015_RS12460
uniprot id: A0A0S2K389
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

161398:PP2015 RS16050
gene id: 161398:PP2015_RS16050
uniprot id: A0A0S2K542
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

161398:PP2015 RS13855
gene id: 161398:PP2015_RS13855
uniprot id: A0A0S2K540
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

161398:PP2015 RS07600
gene id: 161398:PP2015_RS07600
uniprot id: A0A0S2K128
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS06250
gene id: 161398:PP2015_RS06250
uniprot id: A0A0S2K0C9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS13790
gene id: 161398:PP2015_RS13790
uniprot id: A0A0S2K4F2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

161398:PP2015 RS17705
gene id: 161398:PP2015_RS17705
uniprot id: A0A0S2K695
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

161398:PP2015 RS16270
gene id: 161398:PP2015_RS16270
uniprot id: A0A0S2K6H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

161398:PP2015 RS07090
gene id: 161398:PP2015_RS07090
uniprot id: A0A0S2K0Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS20435
gene id: 161398:PP2015_RS20435
uniprot id: A0A0S2K7U1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS12900
gene id: 161398:PP2015_RS12900
uniprot id: A0A0S2K3Y6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS06740
gene id: 161398:PP2015_RS06740
uniprot id: A0A0S2K0P0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS00315
gene id: 161398:PP2015_RS00315
uniprot id: A0A0S2JXF1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

161398:PP2015 RS03900
gene id: 161398:PP2015_RS03900
uniprot id: A0A0S2JZS2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

161398:PP2015 RS07035
gene id: 161398:PP2015_RS07035
uniprot id: A0A0S2K0R3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

161398:PP2015 RS03720
gene id: 161398:PP2015_RS03720
uniprot id: A0A0S2JZ11
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

161398:PP2015 RS03710
gene id: 161398:PP2015_RS03710
uniprot id: A0A0S2JZM1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

161398:PP2015 RS09930
gene id: 161398:PP2015_RS09930
uniprot id: A0A0S2K1T1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161398:PP2015 RS12765
gene id: 161398:PP2015_RS12765
uniprot id: A0A0S2K4L2
names: Similarity
messages: Belongs to the type IA topoisomerase family.

161398:PP2015 RS21180
gene id: 161398:PP2015_RS21180
uniprot id: A0A0S2K8F4
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

161398:PP2015 RS19005
gene id: 161398:PP2015_RS19005
uniprot id: A0A0S2K6Z7
names: Similarity
messages: Belongs to the CFA/CMAS family.

161398:PP2015 RS19525
gene id: 161398:PP2015_RS19525
uniprot id: A0A0S2K7D4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS13975
gene id: 161398:PP2015_RS13975
uniprot id: A0A0S2K4K9
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS01635
gene id: 161398:PP2015_RS01635
uniprot id: A0A0S2JYE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

161398:PP2015 RS11970
gene id: 161398:PP2015_RS11970
uniprot id: A0A0S2K416
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

161398:PP2015 RS10975
gene id: 161398:PP2015_RS10975
uniprot id: A0A0S2K3M9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS18855
gene id: 161398:PP2015_RS18855
uniprot id: A0A0S2K6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

161398:PP2015 RS04565
gene id: 161398:PP2015_RS04565
uniprot id: A0A0S2K057
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

161398:PP2015 RS11635
gene id: 161398:PP2015_RS11635
uniprot id: A0A0S2K326
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

161398:PP2015 RS00285
gene id: 161398:PP2015_RS00285
uniprot id: A0A0S2JX42
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

161398:PP2015 RS14425
gene id: 161398:PP2015_RS14425
uniprot id: A0A0S2K508
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS02695
gene id: 161398:PP2015_RS02695
uniprot id: A0A0S2JYD3
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

161398:PP2015 RS02180
gene id: 161398:PP2015_RS02180
uniprot id: A0A0S2JY86
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

161398:PP2015 RS08470
gene id: 161398:PP2015_RS08470
uniprot id: A0A0S2K287
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

161398:PP2015 RS09515
gene id: 161398:PP2015_RS09515
uniprot id: A0A0S2K360
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS07785
gene id: 161398:PP2015_RS07785
uniprot id: A0A0S2K165
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

161398:PP2015 RS00395
gene id: 161398:PP2015_RS00395
uniprot id: A0A0S2JXG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

161398:PP2015 RS01545
gene id: 161398:PP2015_RS01545
uniprot id: A0A0S2JYD6
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

161398:PP2015 RS12430
gene id: 161398:PP2015_RS12430
uniprot id: A0A0S2K4F3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

161398:PP2015 RS13750
gene id: 161398:PP2015_RS13750
uniprot id: A0A0S2K4M6
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

161398:PP2015 RS04865
gene id: 161398:PP2015_RS04865
uniprot id: A0A0S2JZ73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

161398:PP2015 RS01710
gene id: 161398:PP2015_RS01710
uniprot id: A0A0S2JYB0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

161398:PP2015 RS00495
gene id: 161398:PP2015_RS00495
uniprot id: A0A0S2JX38
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS02880
gene id: 161398:PP2015_RS02880
uniprot id: A0A0S2JYG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

161398:PP2015 RS02125
gene id: 161398:PP2015_RS02125
uniprot id: A0A0S2JY68
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

161398:PP2015 RS05025
gene id: 161398:PP2015_RS05025
uniprot id: A0A0S2JZP8
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

161398:PP2015 RS10410
gene id: 161398:PP2015_RS10410
uniprot id: A0A0S2K2U1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

161398:PP2015 RS08955
gene id: 161398:PP2015_RS08955
uniprot id: A0A0S2K252
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

161398:PP2015 RS12150
gene id: 161398:PP2015_RS12150
uniprot id: A0A0S2K3H8
names: Similarity
messages: Belongs to the peptidase M17 family.

161398:PP2015 RS15550
gene id: 161398:PP2015_RS15550
uniprot id: A0A0S2K6D3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS19555
gene id: 161398:PP2015_RS19555
uniprot id: A0A0S2K7M3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

161398:PP2015 RS05590
gene id: 161398:PP2015_RS05590
uniprot id: A0A0S2JZZ0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161398:PP2015 RS05325
gene id: 161398:PP2015_RS05325
uniprot id: A0A0S2K0I7
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS18480
gene id: 161398:PP2015_RS18480
uniprot id: A0A0S2K731
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

161398:PP2015 RS05985
gene id: 161398:PP2015_RS05985
uniprot id: A0A0S2JZP6
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

161398:PP2015 RS06715
gene id: 161398:PP2015_RS06715
uniprot id: A0A0S2K040
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

161398:PP2015 RS02920
gene id: 161398:PP2015_RS02920
uniprot id: A0A0S2JYX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

161398:PP2015 RS12365
gene id: 161398:PP2015_RS12365
uniprot id: A0A0S2K353
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

161398:PP2015 RS05335
gene id: 161398:PP2015_RS05335
uniprot id: A0A0S2K0G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS09080
gene id: 161398:PP2015_RS09080
uniprot id: A0A0S2K2L4
names: Similarity
messages: Belongs to the fructosamine kinase family.

161398:PP2015 RS02295
gene id: 161398:PP2015_RS02295
uniprot id: A0A0S2JY59
names: Similarity
messages: Belongs to the HsdR family.

161398:PP2015 RS04615
gene id: 161398:PP2015_RS04615
uniprot id: A0A0S2JZP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

161398:PP2015 RS16790
gene id: 161398:PP2015_RS16790
uniprot id: A0A0S2K6A8
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

161398:PP2015 RS04735
gene id: 161398:PP2015_RS04735
uniprot id: A0A0S2JZ86
names: Function
names: Similarity
messages: Belongs to the LuxC family.
messages: LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.

161398:PP2015 RS01625
gene id: 161398:PP2015_RS01625
uniprot id: A0A0S2JYF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS10140
gene id: 161398:PP2015_RS10140
uniprot id: A0A0S2K362
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS21090
gene id: 161398:PP2015_RS21090
uniprot id: A0A0S2K9E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Membrane

161398:PP2015 RS05085
gene id: 161398:PP2015_RS05085
uniprot id: A0A0S2JZ96
names: Subcellular Location Annotation
messages: Cytoplasm

161398:PP2015 RS06415
gene id: 161398:PP2015_RS06415
uniprot id: A0A0S2K0P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

161398:PP2015 RS16250
gene id: 161398:PP2015_RS16250
uniprot id: A0A0S2K6N1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

161398:PP2015 RS01845
gene id: 161398:PP2015_RS01845
uniprot id: A0A0S2JYM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

161398:PP2015 RS12585
gene id: 161398:PP2015_RS12585
uniprot id: A0A0S2K4V5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

161398:PP2015 RS00065
gene id: 161398:PP2015_RS00065
uniprot id: A0A0S2JXR8
names: Similarity
messages: Belongs to the IMPACT family.

161398:PP2015 RS01925
gene id: 161398:PP2015_RS01925
uniprot id: A0A0S2JYN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

161398:PP2015 RS11085
gene id: 161398:PP2015_RS11085
uniprot id: A0A0S2K3R0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

161398:PP2015 RS16230
gene id: 161398:PP2015_RS16230
uniprot id: A0A4Q7IIT8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS01825
gene id: 161398:PP2015_RS01825
uniprot id: A0A0S2JXS4
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS11060
gene id: 161398:PP2015_RS11060
uniprot id: A0A0S2K2Q6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS01935
gene id: 161398:PP2015_RS01935
uniprot id: A0A0S2JY42
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

161398:PP2015 RS13345
gene id: 161398:PP2015_RS13345
uniprot id: A0A0S2K471
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

161398:PP2015 RS01175
gene id: 161398:PP2015_RS01175
uniprot id: A0A0S2JXN1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

161398:PP2015 RS10505
gene id: 161398:PP2015_RS10505
uniprot id: A0A0S2K2S4
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

161398:PP2015 RS01015
gene id: 161398:PP2015_RS01015
uniprot id: A0A0S2JX69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

161398:PP2015 RS09215
gene id: 161398:PP2015_RS09215
uniprot id: A0A0S2K1E8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

161398:PP2015 RS13640
gene id: 161398:PP2015_RS13640
uniprot id: A0A0S2K5D9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

161398:PP2015 RS14045
gene id: 161398:PP2015_RS14045
uniprot id: A0A0S2K5C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

161398:PP2015 RS01470
gene id: 161398:PP2015_RS01470
uniprot id: A0A0S2JXU1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

161398:PP2015 RS00505
gene id: 161398:PP2015_RS00505
uniprot id: A0A0S2JXA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

161398:PP2015 RS13820
gene id: 161398:PP2015_RS13820
uniprot id: A0A0S2K3W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

161398:PP2015 RS18525
gene id: 161398:PP2015_RS18525
uniprot id: A0A0S2K703
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

161398:PP2015 RS15045
gene id: 161398:PP2015_RS15045
uniprot id: A0A0S2K5T5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

161398:PP2015 RS02960
gene id: 161398:PP2015_RS02960
uniprot id: A0A0S2JYN7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

161398:PP2015 RS16445
gene id: 161398:PP2015_RS16445
uniprot id: A0A0S2K6F2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

161398:PP2015 RS03615
gene id: 161398:PP2015_RS03615
uniprot id: A0A0S2JZ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

161398:PP2015 RS10495
gene id: 161398:PP2015_RS10495
uniprot id: A0A0S2K3D7
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS17435
gene id: 161398:PP2015_RS17435
uniprot id: A0A0S2K5W5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS01895
gene id: 161398:PP2015_RS01895
uniprot id: A0A0S2JXY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

161398:PP2015 RS10015
gene id: 161398:PP2015_RS10015
uniprot id: A0A0S2K2D1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

161398:PP2015 RS18045
gene id: 161398:PP2015_RS18045
uniprot id: A0A0S2K6P5
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS06280
gene id: 161398:PP2015_RS06280
uniprot id: A0A0S2K0K3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

161398:PP2015 RS00660
gene id: 161398:PP2015_RS00660
uniprot id: A0A0S2JX61
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

161398:PP2015 RS08615
gene id: 161398:PP2015_RS08615
uniprot id: A0A0S2K2A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

161398:PP2015 RS01020
gene id: 161398:PP2015_RS01020
uniprot id: A0A0S2JXN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

161398:PP2015 RS20930
gene id: 161398:PP2015_RS20930
uniprot id: A0A0S2K9B4
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS06840
gene id: 161398:PP2015_RS06840
uniprot id: A0A0S2K0V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

161398:PP2015 RS21210
gene id: 161398:PP2015_RS21210
uniprot id: A0A0S2K8E9
names: Similarity
messages: Belongs to the disproportionating enzyme family.

161398:PP2015 RS21480
gene id: 161398:PP2015_RS21480
uniprot id: A0A0S2K8K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

161398:PP2015 RS13875
gene id: 161398:PP2015_RS13875
uniprot id: A0A0S2K5J1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

161398:PP2015 RS00250
gene id: 161398:PP2015_RS00250
uniprot id: A0A0S2JX89
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

161398:PP2015 RS09600
gene id: 161398:PP2015_RS09600
uniprot id: A0A0S2K367
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

161398:PP2015 RS21365
gene id: 161398:PP2015_RS21365
uniprot id: A0A0S2K8Z6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

161398:PP2015 RS09350
gene id: 161398:PP2015_RS09350
uniprot id: A0A0S2K272
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

161398:PP2015 RS19260
gene id: 161398:PP2015_RS19260
uniprot id: A0A0S2K7F7
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS14635
gene id: 161398:PP2015_RS14635
uniprot id: A0A0S2K5Z1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

161398:PP2015 RS06980
gene id: 161398:PP2015_RS06980
uniprot id: A0A0S2K0R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS05600
gene id: 161398:PP2015_RS05600
uniprot id: A0A0S2K077
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

161398:PP2015 RS10485
gene id: 161398:PP2015_RS10485
uniprot id: A0A0S2K2V6
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS00800
gene id: 161398:PP2015_RS00800
uniprot id: A0A0S2JXY7
names: Similarity
messages: Belongs to the UPF0270 family.

161398:PP2015 RS14905
gene id: 161398:PP2015_RS14905
uniprot id: A0A0S2K511
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

161398:PP2015 RS17815
gene id: 161398:PP2015_RS17815
uniprot id: A0A0S2K743
names: Similarity
messages: Belongs to the aspartokinase family.

161398:PP2015 RS17795
gene id: 161398:PP2015_RS17795
uniprot id: A0A0S2K6R9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

161398:PP2015 RS02035
gene id: 161398:PP2015_RS02035
uniprot id: A0A0S2JYM3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

161398:PP2015 RS08905
gene id: 161398:PP2015_RS08905
uniprot id: A0A0S2K2H1
names: Similarity
messages: Belongs to the UPF0434 family.

161398:PP2015 RS15975
gene id: 161398:PP2015_RS15975
uniprot id: A0A0S2K5I6
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

161398:PP2015 RS07280
gene id: 161398:PP2015_RS07280
uniprot id: A0A0S2K0V9
names: Similarity
messages: Belongs to the pirin family.

161398:PP2015 RS00870
gene id: 161398:PP2015_RS00870
uniprot id: A0A0S2JXV3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

161398:PP2015 RS07530
gene id: 161398:PP2015_RS07530
uniprot id: A0A0S2K1I1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

161398:PP2015 RS14240
gene id: 161398:PP2015_RS14240
uniprot id: A0A0S2K4S3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

161398:PP2015 RS06180
gene id: 161398:PP2015_RS06180
uniprot id: A0A0S2K102
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS12610
gene id: 161398:PP2015_RS12610
uniprot id: A0A0S2K3A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS00070
gene id: 161398:PP2015_RS00070
uniprot id: A0A0S2JWR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

161398:PP2015 RS01190
gene id: 161398:PP2015_RS01190
uniprot id: A0A0S2JX97
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

161398:PP2015 RS16275
gene id: 161398:PP2015_RS16275
uniprot id: A0A0S2K6H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

161398:PP2015 RS10470
gene id: 161398:PP2015_RS10470
uniprot id: A0A0S2K247
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

161398:PP2015 RS00875
gene id: 161398:PP2015_RS00875
uniprot id: A0A0S2JXZ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

161398:PP2015 RS02475
gene id: 161398:PP2015_RS02475
uniprot id: A0A0S2JY92
names: Subcellular Location Annotation
messages: Cytoplasm

161398:PP2015 RS15935
gene id: 161398:PP2015_RS15935
uniprot id: A0A0S2K6C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS18415
gene id: 161398:PP2015_RS18415
uniprot id: A0A0S2K6N4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS03485
gene id: 161398:PP2015_RS03485
uniprot id: A0A0S2JZF0
names: Similarity
messages: Belongs to the DEAD box helicase family.

161398:PP2015 RS11885
gene id: 161398:PP2015_RS11885
uniprot id: A0A0S2K2V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

161398:PP2015 RS14575
gene id: 161398:PP2015_RS14575
uniprot id: A0A0S2K4Y4
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS11925
gene id: 161398:PP2015_RS11925
uniprot id: A0A0S2K451
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

161398:PP2015 RS09890
gene id: 161398:PP2015_RS09890
uniprot id: A0A0S2K3B8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

161398:PP2015 RS04365
gene id: 161398:PP2015_RS04365
uniprot id: A0A0S2JZZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

161398:PP2015 RS14315
gene id: 161398:PP2015_RS14315
uniprot id: A0A0S2K5H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

161398:PP2015 RS12345
gene id: 161398:PP2015_RS12345
uniprot id: A0A0S2K4E6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

161398:PP2015 RS19545
gene id: 161398:PP2015_RS19545
uniprot id: A0A0S2K8I0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

161398:PP2015 RS03160
gene id: 161398:PP2015_RS03160
uniprot id: A0A0S2JZ91
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

161398:PP2015 RS21435
gene id: 161398:PP2015_RS21435
uniprot id: A0A0S2K9E3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

161398:PP2015 RS14060
gene id: 161398:PP2015_RS14060
uniprot id: A0A0S2K425
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

161398:PP2015 RS09500
gene id: 161398:PP2015_RS09500
uniprot id: A0A0S2K2T5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

161398:PP2015 RS15595
gene id: 161398:PP2015_RS15595
uniprot id: A0A0S2K5C6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS04965
gene id: 161398:PP2015_RS04965
uniprot id: A0A0S2K0C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

161398:PP2015 RS18145
gene id: 161398:PP2015_RS18145
uniprot id: A0A0S2K6G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

161398:PP2015 RS20950
gene id: 161398:PP2015_RS20950
uniprot id: A0A0S2K944
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS05655
gene id: 161398:PP2015_RS05655
uniprot id: A0A0S2K0Q1
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

161398:PP2015 RS04395
gene id: 161398:PP2015_RS04395
uniprot id: A0A0S2K009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

161398:PP2015 RS11150
gene id: 161398:PP2015_RS11150
uniprot id: A0A0S2K424
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS08945
gene id: 161398:PP2015_RS08945
uniprot id: A0A0S2K179
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

161398:PP2015 RS16455
gene id: 161398:PP2015_RS16455
uniprot id: A0A0S2K5B1
names: Function
names: Similarity
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

161398:PP2015 RS13455
gene id: 161398:PP2015_RS13455
uniprot id: A0A0S2K4R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

161398:PP2015 RS03495
gene id: 161398:PP2015_RS03495
uniprot id: A0A0S2JZC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

161398:PP2015 RS13380
gene id: 161398:PP2015_RS13380
uniprot id: A0A0S2K4F7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS15905
gene id: 161398:PP2015_RS15905
uniprot id: A0A0S2K5P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS13180
gene id: 161398:PP2015_RS13180
uniprot id: A0A0S2K3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

161398:PP2015 RS10355
gene id: 161398:PP2015_RS10355
uniprot id: A0A0S2K3K7
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS15065
gene id: 161398:PP2015_RS15065
uniprot id: A0A0S2K644
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

161398:PP2015 RS08855
gene id: 161398:PP2015_RS08855
uniprot id: A0A0S2K2G4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

161398:PP2015 RS20490
gene id: 161398:PP2015_RS20490
uniprot id: A0A0S2K830
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

161398:PP2015 RS18645
gene id: 161398:PP2015_RS18645
uniprot id: A0A0S2K7Q4
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

161398:PP2015 RS08875
gene id: 161398:PP2015_RS08875
uniprot id: A0A0S2K238
names: Similarity
messages: Belongs to the citrate synthase family.

161398:PP2015 RS09485
gene id: 161398:PP2015_RS09485
uniprot id: A0A0S2K223
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

161398:PP2015 RS07820
gene id: 161398:PP2015_RS07820
uniprot id: A0A0S2K1C3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

161398:PP2015 RS20835
gene id: 161398:PP2015_RS20835
uniprot id: A0A0S2K8X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

161398:PP2015 RS06845
gene id: 161398:PP2015_RS06845
uniprot id: A0A0S2K1L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

161398:PP2015 RS14845
gene id: 161398:PP2015_RS14845
uniprot id: A0A0S2K5R1
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

161398:PP2015 RS16645
gene id: 161398:PP2015_RS16645
uniprot id: A0A0S2K640
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

161398:PP2015 RS14065
gene id: 161398:PP2015_RS14065
uniprot id: A0A0S2K530
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS20315
gene id: 161398:PP2015_RS20315
uniprot id: A0A0S2K7S4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

161398:PP2015 RS16240
gene id: 161398:PP2015_RS16240
uniprot id: A0A0S2K5W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

161398:PP2015 RS21405
gene id: 161398:PP2015_RS21405
uniprot id: A0A0S2K8P7
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

161398:PP2015 RS12080
gene id: 161398:PP2015_RS12080
uniprot id: A0A0S2K475
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS06400
gene id: 161398:PP2015_RS06400
uniprot id: A0A0S2K0E2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

161398:PP2015 RS03470
gene id: 161398:PP2015_RS03470
uniprot id: A0A0S2JZF8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS15950
gene id: 161398:PP2015_RS15950
uniprot id: A0A0S2K5M5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

161398:PP2015 RS02120
gene id: 161398:PP2015_RS02120
uniprot id: A0A0S2JYN3
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS16030
gene id: 161398:PP2015_RS16030
uniprot id: A0A0S2K5P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

161398:PP2015 RS12740
gene id: 161398:PP2015_RS12740
uniprot id: A0A5R9Q113
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS15545
gene id: 161398:PP2015_RS15545
uniprot id: A0A0S2K5B8
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

161398:PP2015 RS04860
gene id: 161398:PP2015_RS04860
uniprot id: A0A0S2JZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

161398:PP2015 RS06140
gene id: 161398:PP2015_RS06140
uniprot id: A0A0S2K0A3
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS13705
gene id: 161398:PP2015_RS13705
uniprot id: A0A0S2K450
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

161398:PP2015 RS07690
gene id: 161398:PP2015_RS07690
uniprot id: A0A0S2K1L3
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

161398:PP2015 RS02990
gene id: 161398:PP2015_RS02990
uniprot id: A0A0S2JY78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

161398:PP2015 RS04490
gene id: 161398:PP2015_RS04490
uniprot id: A0A0S2JZH2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

161398:PP2015 RS19330
gene id: 161398:PP2015_RS19330
uniprot id: A0A0S2K7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS04030
gene id: 161398:PP2015_RS04030
uniprot id: A0A0S2JZB1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS07700
gene id: 161398:PP2015_RS07700
uniprot id: A0A0S2K0J8
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

161398:PP2015 RS10655
gene id: 161398:PP2015_RS10655
uniprot id: A0A0S2K3G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS09295
gene id: 161398:PP2015_RS09295
uniprot id: A0A0S2K212
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

161398:PP2015 RS12620
gene id: 161398:PP2015_RS12620
uniprot id: A0A0S2K4D2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

161398:PP2015 RS06895
gene id: 161398:PP2015_RS06895
uniprot id: A0A0S2K068
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

161398:PP2015 RS06395
gene id: 161398:PP2015_RS06395
uniprot id: A0A0S2K126
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS20075
gene id: 161398:PP2015_RS20075
uniprot id: A0A0S2K7P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

161398:PP2015 RS10765
gene id: 161398:PP2015_RS10765
uniprot id: A0A0S2K3J5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS02400
gene id: 161398:PP2015_RS02400
uniprot id: A0A0S2JY87
names: Similarity
messages: Belongs to the FMO family.

161398:PP2015 RS08435
gene id: 161398:PP2015_RS08435
uniprot id: A0A0S2K288
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

161398:PP2015 RS11810
gene id: 161398:PP2015_RS11810
uniprot id: A0A0S2K443
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS18680
gene id: 161398:PP2015_RS18680
uniprot id: A0A0S2K7L6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS05310
gene id: 161398:PP2015_RS05310
uniprot id: A0A0S2JZL2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

161398:PP2015 RS04250
gene id: 161398:PP2015_RS04250
uniprot id: A0A0S2JYU4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

161398:PP2015 RS03725
gene id: 161398:PP2015_RS03725
uniprot id: A0A0S2JZM5
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

161398:PP2015 RS21100
gene id: 161398:PP2015_RS21100
uniprot id: A0A0S2K8F6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

161398:PP2015 RS07020
gene id: 161398:PP2015_RS07020
uniprot id: A0A0S2K1H6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

161398:PP2015 RS06710
gene id: 161398:PP2015_RS06710
uniprot id: A0A0S2K0U9
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

161398:PP2015 RS12820
gene id: 161398:PP2015_RS12820
uniprot id: A0A0S2K3P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS21430
gene id: 161398:PP2015_RS21430
uniprot id: A0A0S2K9I7
names: Similarity
messages: Belongs to the GbsR family.

161398:PP2015 RS14210
gene id: 161398:PP2015_RS14210
uniprot id: A0A0S2K4G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

161398:PP2015 RS17810
gene id: 161398:PP2015_RS17810
uniprot id: A0A0S2K7D1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

161398:PP2015 RS13835
gene id: 161398:PP2015_RS13835
uniprot id: A0A0S2K3X8
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS14580
gene id: 161398:PP2015_RS14580
uniprot id: A0A0S2K4C9
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

161398:PP2015 RS14325
gene id: 161398:PP2015_RS14325
uniprot id: A0A0S2K5G8
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

161398:PP2015 RS00205
gene id: 161398:PP2015_RS00205
uniprot id: A0A0S2JX27
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

161398:PP2015 RS10730
gene id: 161398:PP2015_RS10730
uniprot id: A0A0S2K3H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS00965
gene id: 161398:PP2015_RS00965
uniprot id: A0A0S2JX48
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS02795
gene id: 161398:PP2015_RS02795
uniprot id: A0A0S2JYG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

161398:PP2015 RS00835
gene id: 161398:PP2015_RS00835
uniprot id: A0A0S2JXG3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

161398:PP2015 RS14485
gene id: 161398:PP2015_RS14485
uniprot id: A0A0S2K5K5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

161398:PP2015 RS13210
gene id: 161398:PP2015_RS13210
uniprot id: A0A0S2K4V0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

161398:PP2015 RS03645
gene id: 161398:PP2015_RS03645
uniprot id: A0A0S2JZL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

161398:PP2015 RS09750
gene id: 161398:PP2015_RS09750
uniprot id: A0A0S2K2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

161398:PP2015 RS13910
gene id: 161398:PP2015_RS13910
uniprot id: A0A0S2K4Q4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

161398:PP2015 RS01035
gene id: 161398:PP2015_RS01035
uniprot id: A0A0S2JXY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

161398:PP2015 RS02170
gene id: 161398:PP2015_RS02170
uniprot id: A0A0S2JYR5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

161398:PP2015 RS04805
gene id: 161398:PP2015_RS04805
uniprot id: A0A0S2K0A0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

161398:PP2015 RS04700
gene id: 161398:PP2015_RS04700
uniprot id: A0A0S2JZJ6
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

161398:PP2015 RS03510
gene id: 161398:PP2015_RS03510
uniprot id: A0A0S2JYW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

161398:PP2015 RS17125
gene id: 161398:PP2015_RS17125
uniprot id: A0A0S2K655
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

161398:PP2015 RS20900
gene id: 161398:PP2015_RS20900
uniprot id: A0A0S2K8M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS09900
gene id: 161398:PP2015_RS09900
uniprot id: A0A0S2K306
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

161398:PP2015 RS05280
gene id: 161398:PP2015_RS05280
uniprot id: A0A0S2JZV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

161398:PP2015 RS00970
gene id: 161398:PP2015_RS00970
uniprot id: A0A0S2JXG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

161398:PP2015 RS03550
gene id: 161398:PP2015_RS03550
uniprot id: A0A0S2JYJ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS14050
gene id: 161398:PP2015_RS14050
uniprot id: A0A0S2K5B5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

161398:PP2015 RS01400
gene id: 161398:PP2015_RS01400
uniprot id: A0A0S2JXP5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

161398:PP2015 RS16895
gene id: 161398:PP2015_RS16895
uniprot id: A0A0S2K693
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS02515
gene id: 161398:PP2015_RS02515
uniprot id: A0A0S2JYQ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161398:PP2015 RS03655
gene id: 161398:PP2015_RS03655
uniprot id: A0A0S2JZF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

161398:PP2015 RS02255
gene id: 161398:PP2015_RS02255
uniprot id: A0A0S2JXT8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

161398:PP2015 RS04770
gene id: 161398:PP2015_RS04770
uniprot id: A0A0S2JZ40
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

161398:PP2015 RS14900
gene id: 161398:PP2015_RS14900
uniprot id: A0A0S2K4S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS17805
gene id: 161398:PP2015_RS17805
uniprot id: A0A0S2K7E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

161398:PP2015 RS17255
gene id: 161398:PP2015_RS17255
uniprot id: A0A0S2K5S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

161398:PP2015 RS10680
gene id: 161398:PP2015_RS10680
uniprot id: A0A0S2K3G3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS18690
gene id: 161398:PP2015_RS18690
uniprot id: A0A0S2K6T4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161398:PP2015 RS16265
gene id: 161398:PP2015_RS16265
uniprot id: A0A0S2K6R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

161398:PP2015 RS04665
gene id: 161398:PP2015_RS04665
uniprot id: A0A0S2K032
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

161398:PP2015 RS16060
gene id: 161398:PP2015_RS16060
uniprot id: A0A0S2K5I1
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

161398:PP2015 RS06990
gene id: 161398:PP2015_RS06990
uniprot id: A0A0S2K0T6
names: Similarity
messages: Belongs to the universal stress protein A family.

161398:PP2015 RS16245
gene id: 161398:PP2015_RS16245
uniprot id: A0A0S2K6E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

161398:PP2015 RS07460
gene id: 161398:PP2015_RS07460
uniprot id: A0A0S2K0G0
names: Similarity
messages: Belongs to the aspartokinase family.

161398:PP2015 RS16225
gene id: 161398:PP2015_RS16225
uniprot id: A0A0S2K5L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

161398:PP2015 RS17000
gene id: 161398:PP2015_RS17000
uniprot id: A0A0S2K755
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

161398:PP2015 RS16180
gene id: 161398:PP2015_RS16180
uniprot id: A0A0S2K6F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

161398:PP2015 RS14130
gene id: 161398:PP2015_RS14130
uniprot id: A0A0S2K5D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

161398:PP2015 RS15560
gene id: 161398:PP2015_RS15560
uniprot id: A0A0S2K646
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

161398:PP2015 RS12785
gene id: 161398:PP2015_RS12785
uniprot id: A0A0S2K462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS11920
gene id: 161398:PP2015_RS11920
uniprot id: A0A0S2K444
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

161398:PP2015 RS09645
gene id: 161398:PP2015_RS09645
uniprot id: A0A0S2K264
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

161398:PP2015 RS10545
gene id: 161398:PP2015_RS10545
uniprot id: A0A0S2K2Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS08390
gene id: 161398:PP2015_RS08390
uniprot id: A0A0S2K267
names: Similarity
messages: Belongs to the pyruvate kinase family.

161398:PP2015 RS13565
gene id: 161398:PP2015_RS13565
uniprot id: A0A0S2K503
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

161398:PP2015 RS12475
gene id: 161398:PP2015_RS12475
uniprot id: A0A0S2K3Z0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

161398:PP2015 RS12935
gene id: 161398:PP2015_RS12935
uniprot id: A0A0S2K4Q3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

161398:PP2015 RS08555
gene id: 161398:PP2015_RS08555
uniprot id: A0A0S2K1M0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

161398:PP2015 RS10515
gene id: 161398:PP2015_RS10515
uniprot id: A0A0S2K3D8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS09975
gene id: 161398:PP2015_RS09975
uniprot id: A0A0S2K327
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

161398:PP2015 RS09670
gene id: 161398:PP2015_RS09670
uniprot id: A0A0S2K2W8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

161398:PP2015 RS15230
gene id: 161398:PP2015_RS15230
uniprot id: A0A0S2K5Y7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

161398:PP2015 RS07295
gene id: 161398:PP2015_RS07295
uniprot id: A0A0S2K163
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS01605
gene id: 161398:PP2015_RS01605
uniprot id: A0A0S2JYH8
names: Similarity
messages: Belongs to the BolA/IbaG family.

161398:PP2015 RS09535
gene id: 161398:PP2015_RS09535
uniprot id: A0A0S2K266
names: Similarity
messages: Belongs to the glutamate synthase family.

161398:PP2015 RS10620
gene id: 161398:PP2015_RS10620
uniprot id: A0A0S2K269
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS15540
gene id: 161398:PP2015_RS15540
uniprot id: A0A0S2K547
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

161398:PP2015 RS00805
gene id: 161398:PP2015_RS00805
uniprot id: A0A0S2JXI6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

161398:PP2015 RS15990
gene id: 161398:PP2015_RS15990
uniprot id: A0A0S2K689
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

161398:PP2015 RS12780
gene id: 161398:PP2015_RS12780
uniprot id: A0A0S2K4G2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

161398:PP2015 RS16490
gene id: 161398:PP2015_RS16490
uniprot id: A0A0S2K6J5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

161398:PP2015 RS00845
gene id: 161398:PP2015_RS00845
uniprot id: A0A0S2JY40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS07490
gene id: 161398:PP2015_RS07490
uniprot id: A0A0S2K0R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

161398:PP2015 RS19125
gene id: 161398:PP2015_RS19125
uniprot id: A0A0S2K7H2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS02010
gene id: 161398:PP2015_RS02010
uniprot id: A0A0S2JXQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

161398:PP2015 RS15390
gene id: 161398:PP2015_RS15390
uniprot id: A0A0S2K618
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

161398:PP2015 RS00180
gene id: 161398:PP2015_RS00180
uniprot id: A0A0S2JXJ0
names: PTM
messages: Binds 1 heme group per subunit.

161398:PP2015 RS21265
gene id: 161398:PP2015_RS21265
uniprot id: A0A0S2K8I5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS06825
gene id: 161398:PP2015_RS06825
uniprot id: A0A0S2K1B1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS06425
gene id: 161398:PP2015_RS06425
uniprot id: A0A0S2K0G7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

161398:PP2015 RS05380
gene id: 161398:PP2015_RS05380
uniprot id: A0A0S2K0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS02715
gene id: 161398:PP2015_RS02715
uniprot id: A0A0S2JYE8
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS20585
gene id: 161398:PP2015_RS20585
uniprot id: A0A0S2K8A0
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS07670
gene id: 161398:PP2015_RS07670
uniprot id: A0A0S2K1S3
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

161398:PP2015 RS04960
gene id: 161398:PP2015_RS04960
uniprot id: A0A0S2JZJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

161398:PP2015 RS05120
gene id: 161398:PP2015_RS05120
uniprot id: A0A0S2JZP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS16005
gene id: 161398:PP2015_RS16005
uniprot id: A0A0S2K5K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

161398:PP2015 RS07105
gene id: 161398:PP2015_RS07105
uniprot id: A0A0S2K1G4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

161398:PP2015 RS01300
gene id: 161398:PP2015_RS01300
uniprot id: A0A0S2JXR9
names: Similarity
messages: Belongs to the UPF0758 family.

161398:PP2015 RS14700
gene id: 161398:PP2015_RS14700
uniprot id: A0A0S2K5M0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

161398:PP2015 RS08710
gene id: 161398:PP2015_RS08710
uniprot id: A0A0S2K131
names: Similarity
messages: Belongs to the proline racemase family.

161398:PP2015 RS11965
gene id: 161398:PP2015_RS11965
uniprot id: A0A0S2K2X6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS03040
gene id: 161398:PP2015_RS03040
uniprot id: A0A0S2JY90
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

161398:PP2015 RS01840
gene id: 161398:PP2015_RS01840
uniprot id: A0A0S2JYI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

161398:PP2015 RS05620
gene id: 161398:PP2015_RS05620
uniprot id: A0A0S2JZZ2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

161398:PP2015 RS06060
gene id: 161398:PP2015_RS06060
uniprot id: A0A0S2K093
names: Similarity
messages: Belongs to the peptidase S8 family.

161398:PP2015 RS14275
gene id: 161398:PP2015_RS14275
uniprot id: A0A0S2K4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

161398:PP2015 RS04640
gene id: 161398:PP2015_RS04640
uniprot id: A0A0S2JZA4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

161398:PP2015 RS14040
gene id: 161398:PP2015_RS14040
uniprot id: A0A0S2K5C1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

161398:PP2015 RS14460
gene id: 161398:PP2015_RS14460
uniprot id: A0A0S2K5G9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

161398:PP2015 RS17335
gene id: 161398:PP2015_RS17335
uniprot id: A0A0S2K5T8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

161398:PP2015 RS11700
gene id: 161398:PP2015_RS11700
uniprot id: A0A0S2K3J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

161398:PP2015 RS10320
gene id: 161398:PP2015_RS10320
uniprot id: A0A0S2K2I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

161398:PP2015 RS14330
gene id: 161398:PP2015_RS14330
uniprot id: A0A0S2K4T8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

161398:PP2015 RS04610
gene id: 161398:PP2015_RS04610
uniprot id: A0A0S2JZ06
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

161398:PP2015 RS06300
gene id: 161398:PP2015_RS06300
uniprot id: A0A0S2K109
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

161398:PP2015 RS14720
gene id: 161398:PP2015_RS14720
uniprot id: A0A0S2K5Q2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

161398:PP2015 RS09885
gene id: 161398:PP2015_RS09885
uniprot id: A0A0S2K2F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

161398:PP2015 RS12320
gene id: 161398:PP2015_RS12320
uniprot id: A0A0S2K4C2
names: Similarity
messages: Belongs to the PhoH family.

161398:PP2015 RS03125
gene id: 161398:PP2015_RS03125
uniprot id: A0A0S2JYI4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

161398:PP2015 RS13920
gene id: 161398:PP2015_RS13920
uniprot id: A0A0S2K4F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

161398:PP2015 RS19985
gene id: 161398:PP2015_RS19985
uniprot id: A0A0S2K7L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

161398:PP2015 RS06490
gene id: 161398:PP2015_RS06490
uniprot id: A0A0S2K0J4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

161398:PP2015 RS07575
gene id: 161398:PP2015_RS07575
uniprot id: A0A0S2K197
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

161398:PP2015 RS19990
gene id: 161398:PP2015_RS19990
uniprot id: A0A0S2K7V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

161398:PP2015 RS18420
gene id: 161398:PP2015_RS18420
uniprot id: A0A0S2K726
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

161398:PP2015 RS13865
gene id: 161398:PP2015_RS13865
uniprot id: A0A0S2K485
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

161398:PP2015 RS18715
gene id: 161398:PP2015_RS18715
uniprot id: A0A0S2K700
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS07565
gene id: 161398:PP2015_RS07565
uniprot id: A0A0S2K1Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

161398:PP2015 RS16085
gene id: 161398:PP2015_RS16085
uniprot id: A0A0S2K5L2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

161398:PP2015 RS02780
gene id: 161398:PP2015_RS02780
uniprot id: A0A0S2JYF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

161398:PP2015 RS15860
gene id: 161398:PP2015_RS15860
uniprot id: A0A0S2K688
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

161398:PP2015 RS15715
gene id: 161398:PP2015_RS15715
uniprot id: A0A0S2K5L7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

161398:PP2015 RS09995
gene id: 161398:PP2015_RS09995
uniprot id: A0A0S2K1T6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

161398:PP2015 RS10045
gene id: 161398:PP2015_RS10045
uniprot id: A0A0S2K244
names: Similarity
messages: Belongs to the transglycosylase Slt family.

161398:PP2015 RS11705
gene id: 161398:PP2015_RS11705
uniprot id: A0A0S2K414
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS09475
gene id: 161398:PP2015_RS09475
uniprot id: A0A0S2K1K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS12825
gene id: 161398:PP2015_RS12825
uniprot id: A0A0S2K3Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS07525
gene id: 161398:PP2015_RS07525
uniprot id: A0A0S2K0F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

161398:PP2015 RS04120
gene id: 161398:PP2015_RS04120
uniprot id: A0A0S2JZ28
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

161398:PP2015 RS09265
gene id: 161398:PP2015_RS09265
uniprot id: A0A0S2K1R0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

161398:PP2015 RS14965
gene id: 161398:PP2015_RS14965
uniprot id: A0A0S2K584
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

161398:PP2015 RS16990
gene id: 161398:PP2015_RS16990
uniprot id: A0A0S2K5W4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS02095
gene id: 161398:PP2015_RS02095
uniprot id: A0A0S2JXS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

161398:PP2015 RS12175
gene id: 161398:PP2015_RS12175
uniprot id: A0A0S2K3M2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

161398:PP2015 RS13425
gene id: 161398:PP2015_RS13425
uniprot id: A0A0S2K5A3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

161398:PP2015 RS11980
gene id: 161398:PP2015_RS11980
uniprot id: A0A0S2K2Y8
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS10600
gene id: 161398:PP2015_RS10600
uniprot id: A0A0S2K3F1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

161398:PP2015 RS20725
gene id: 161398:PP2015_RS20725
uniprot id: A0A0S2K8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

161398:PP2015 RS07800
gene id: 161398:PP2015_RS07800
uniprot id: A0A0S2K1V3
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

161398:PP2015 RS01885
gene id: 161398:PP2015_RS01885
uniprot id: A0A0S2JXM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

161398:PP2015 RS05630
gene id: 161398:PP2015_RS05630
uniprot id: A0A0S2K0N0
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS16875
gene id: 161398:PP2015_RS16875
uniprot id: A0A0S2K5J5
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

161398:PP2015 RS16035
gene id: 161398:PP2015_RS16035
uniprot id: A0A0S2K535
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

161398:PP2015 RS17250
gene id: 161398:PP2015_RS17250
uniprot id: A0A0S2K6C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

161398:PP2015 RS09385
gene id: 161398:PP2015_RS09385
uniprot id: A0A0S2K2K5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS16025
gene id: 161398:PP2015_RS16025
uniprot id: A0A0S2K699
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

161398:PP2015 RS00085
gene id: 161398:PP2015_RS00085
uniprot id: A0A0S2JXH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

161398:PP2015 RS03000
gene id: 161398:PP2015_RS03000
uniprot id: A0A0S2JZ71
names: Similarity
messages: Belongs to the RecJ family.

161398:PP2015 RS18850
gene id: 161398:PP2015_RS18850
uniprot id: A0A0S2K7K7
names: Similarity
messages: Belongs to the UPF0438 family.

161398:PP2015 RS19860
gene id: 161398:PP2015_RS19860
uniprot id: A0A0S2K7J1
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS02050
gene id: 161398:PP2015_RS02050
uniprot id: A0A0S2JY05
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS16650
gene id: 161398:PP2015_RS16650
uniprot id: A0A0S2K6L5
names: Subcellular Location Annotation
messages: Cell inner membrane

161398:PP2015 RS20080
gene id: 161398:PP2015_RS20080
uniprot id: A0A0S2K7Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

161398:PP2015 RS16055
gene id: 161398:PP2015_RS16055
uniprot id: A0A0S2K5K3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS05000
gene id: 161398:PP2015_RS05000
uniprot id: A0A0S2JZN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS09505
gene id: 161398:PP2015_RS09505
uniprot id: A0A0S2K1V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

161398:PP2015 RS09650
gene id: 161398:PP2015_RS09650
uniprot id: A0A0S2K257
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

161398:PP2015 RS19995
gene id: 161398:PP2015_RS19995
uniprot id: A0A0S2K7M7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

161398:PP2015 RS11680
gene id: 161398:PP2015_RS11680
uniprot id: A0A0S2K3L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

161398:PP2015 RS01240
gene id: 161398:PP2015_RS01240
uniprot id: A0A0S2JXB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

161398:PP2015 RS20300
gene id: 161398:PP2015_RS20300
uniprot id: A0A0S2K7R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

161398:PP2015 RS02505
gene id: 161398:PP2015_RS02505
uniprot id: A0A0S2JYY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

161398:PP2015 RS04190
gene id: 161398:PP2015_RS04190
uniprot id: A0A0S2JZ18
names: Similarity
messages: Belongs to the GST superfamily.

161398:PP2015 RS05650
gene id: 161398:PP2015_RS05650
uniprot id: A0A0S2K0T8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

161398:PP2015 RS17655
gene id: 161398:PP2015_RS17655
uniprot id: A0A0S2K6J0
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS14940
gene id: 161398:PP2015_RS14940
uniprot id: A0A0S2K5I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS07080
gene id: 161398:PP2015_RS07080
uniprot id: A0A0S2K1F3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

161398:PP2015 RS20290
gene id: 161398:PP2015_RS20290
uniprot id: A0A0S2K8F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

161398:PP2015 RS10595
gene id: 161398:PP2015_RS10595
uniprot id: A0A0S2K3R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

161398:PP2015 RS14305
gene id: 161398:PP2015_RS14305
uniprot id: A0A0S2K4P6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

161398:PP2015 RS21350
gene id: 161398:PP2015_RS21350
uniprot id: A0A0S2K9H1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

161398:PP2015 RS00140
gene id: 161398:PP2015_RS00140
uniprot id: A0A0S2JXB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

161398:PP2015 RS06305
gene id: 161398:PP2015_RS06305
uniprot id: A0A0S2K0C8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161398:PP2015 RS04620
gene id: 161398:PP2015_RS04620
uniprot id: A0A0S2JZF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

161398:PP2015 RS00275
gene id: 161398:PP2015_RS00275
uniprot id: A0A0S2JX90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

161398:PP2015 RS12465
gene id: 161398:PP2015_RS12465
uniprot id: A0A0S2K3Q6
names: Similarity
messages: Belongs to the YggT family.

161398:PP2015 RS10040
gene id: 161398:PP2015_RS10040
uniprot id: A0A0S2K334
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

161398:PP2015 RS08315
gene id: 161398:PP2015_RS08315
uniprot id: A0A0S2K1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

161398:PP2015 RS03665
gene id: 161398:PP2015_RS03665
uniprot id: A0A0S2JZ44
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS17160
gene id: 161398:PP2015_RS17160
uniprot id: A0A0S2K708
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

161398:PP2015 RS07215
gene id: 161398:PP2015_RS07215
uniprot id: A0A0S2K143
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS08430
gene id: 161398:PP2015_RS08430
uniprot id: A0A0S2K1P0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

161398:PP2015 RS13595
gene id: 161398:PP2015_RS13595
uniprot id: A0A0S2K4J6
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

161398:PP2015 RS12100
gene id: 161398:PP2015_RS12100
uniprot id: A0A0S2K4L0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

161398:PP2015 RS01560
gene id: 161398:PP2015_RS01560
uniprot id: A0A0S2JXV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

161398:PP2015 RS15120
gene id: 161398:PP2015_RS15120
uniprot id: A0A0S2K5V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

161398:PP2015 RS16070
gene id: 161398:PP2015_RS16070
uniprot id: A0A0S2K6C5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

161398:PP2015 RS17320
gene id: 161398:PP2015_RS17320
uniprot id: A0A0S2K739
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

161398:PP2015 RS18980
gene id: 161398:PP2015_RS18980
uniprot id: A0A0S2K866
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

161398:PP2015 RS05370
gene id: 161398:PP2015_RS05370
uniprot id: A0A0S2JZR5
names: Similarity
messages: Belongs to the histone deacetylase family.

161398:PP2015 RS11260
gene id: 161398:PP2015_RS11260
uniprot id: A0A0S2K3N5
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

161398:PP2015 RS20295
gene id: 161398:PP2015_RS20295
uniprot id: A0A0S2K818
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

161398:PP2015 RS13950
gene id: 161398:PP2015_RS13950
uniprot id: A0A0S2K4I1
names: Similarity
messages: Belongs to the BolA/IbaG family.

161398:PP2015 RS14620
gene id: 161398:PP2015_RS14620
uniprot id: A0A0S2K5K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

161398:PP2015 RS04570
gene id: 161398:PP2015_RS04570
uniprot id: A0A0S2K021
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

161398:PP2015 RS17245
gene id: 161398:PP2015_RS17245
uniprot id: A0A0S2K6U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

161398:PP2015 RS00535
gene id: 161398:PP2015_RS00535
uniprot id: A0A0S2JXV5
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

161398:PP2015 RS09420
gene id: 161398:PP2015_RS09420
uniprot id: A0A0S2K2S5
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS18440
gene id: 161398:PP2015_RS18440
uniprot id: A0A0S2K7G7
names: Similarity
messages: Belongs to the peptidase S8 family.

161398:PP2015 RS18835
gene id: 161398:PP2015_RS18835
uniprot id: A0A0S2K7P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

161398:PP2015 RS13620
gene id: 161398:PP2015_RS13620
uniprot id: A0A0S2K4Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

161398:PP2015 RS16505
gene id: 161398:PP2015_RS16505
uniprot id: A0A0S2K5U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

161398:PP2015 RS05300
gene id: 161398:PP2015_RS05300
uniprot id: A0A4Q7ISG4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS02625
gene id: 161398:PP2015_RS02625
uniprot id: A0A0S2JY14
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

161398:PP2015 RS03210
gene id: 161398:PP2015_RS03210
uniprot id: A0A0S2JYR9
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS08310
gene id: 161398:PP2015_RS08310
uniprot id: A0A0S2K250
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

161398:PP2015 RS08885
gene id: 161398:PP2015_RS08885
uniprot id: A0A0S2K1S5
names: Similarity
messages: Belongs to the SufE family.

161398:PP2015 RS20515
gene id: 161398:PP2015_RS20515
uniprot id: A0A0S2K7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS07865
gene id: 161398:PP2015_RS07865
uniprot id: A0A0S2K0N1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS12480
gene id: 161398:PP2015_RS12480
uniprot id: A0A0S2K4F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

161398:PP2015 RS18740
gene id: 161398:PP2015_RS18740
uniprot id: A0A0S2K792
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

161398:PP2015 RS01075
gene id: 161398:PP2015_RS01075
uniprot id: A0A0S2JXJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

161398:PP2015 RS02975
gene id: 161398:PP2015_RS02975
uniprot id: A0A0S2JZD4
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS00825
gene id: 161398:PP2015_RS00825
uniprot id: A0A0S2JX96
names: Similarity
messages: Belongs to the SlyX family.

161398:PP2015 RS06515
gene id: 161398:PP2015_RS06515
uniprot id: A0A0S2K1F8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

161398:PP2015 RS02260
gene id: 161398:PP2015_RS02260
uniprot id: A0A0S2JYT7
names: Similarity
messages: Belongs to the peptidase S8 family.

161398:PP2015 RS10155
gene id: 161398:PP2015_RS10155
uniprot id: A0A0S2K2I1
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS00400
gene id: 161398:PP2015_RS00400
uniprot id: A0A0S2JXW4
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

161398:PP2015 RS13130
gene id: 161398:PP2015_RS13130
uniprot id: A0A0S2K3M0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS13825
gene id: 161398:PP2015_RS13825
uniprot id: A0A0S2K4X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

161398:PP2015 RS09920
gene id: 161398:PP2015_RS09920
uniprot id: A0A0S2K2V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

161398:PP2015 RS08935
gene id: 161398:PP2015_RS08935
uniprot id: A0A0S2K2I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

161398:PP2015 RS08150
gene id: 161398:PP2015_RS08150
uniprot id: A0A0S2K249
names: Similarity
messages: Belongs to the peptidase S66 family.

161398:PP2015 RS14475
gene id: 161398:PP2015_RS14475
uniprot id: A0A0S2K5V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

161398:PP2015 RS17110
gene id: 161398:PP2015_RS17110
uniprot id: A0A0S2K6I2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

161398:PP2015 RS21190
gene id: 161398:PP2015_RS21190
uniprot id: A0A0S2K9D1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

161398:PP2015 RS14955
gene id: 161398:PP2015_RS14955
uniprot id: A0A0S2K501
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

161398:PP2015 RS17425
gene id: 161398:PP2015_RS17425
uniprot id: A0A0S2K6R7
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

161398:PP2015 RS16220
gene id: 161398:PP2015_RS16220
uniprot id: A0A0S2K5N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

161398:PP2015 RS06835
gene id: 161398:PP2015_RS06835
uniprot id: A0A0S2K0E3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

161398:PP2015 RS04780
gene id: 161398:PP2015_RS04780
uniprot id: A0A0S2JZL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

161398:PP2015 RS02175
gene id: 161398:PP2015_RS02175
uniprot id: A0A0S2JXS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

161398:PP2015 RS17670
gene id: 161398:PP2015_RS17670
uniprot id: A0A0S2K6U1
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

161398:PP2015 RS01150
gene id: 161398:PP2015_RS01150
uniprot id: A0A0S2JXJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

161398:PP2015 RS02165
gene id: 161398:PP2015_RS02165
uniprot id: A0A0S2JYU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS14145
gene id: 161398:PP2015_RS14145
uniprot id: A0A0S2K549
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161398:PP2015 RS16560
gene id: 161398:PP2015_RS16560
uniprot id: A0A0S2K616
names: Similarity
messages: Belongs to the Dps family.

161398:PP2015 RS07175
gene id: 161398:PP2015_RS07175
uniprot id: A0A0S2K0K4
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS10360
gene id: 161398:PP2015_RS10360
uniprot id: A0A0S2K3B0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

161398:PP2015 RS18860
gene id: 161398:PP2015_RS18860
uniprot id: A0A0S2K758
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS15700
gene id: 161398:PP2015_RS15700
uniprot id: A0A0S2K4Y1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

161398:PP2015 RS06485
gene id: 161398:PP2015_RS06485
uniprot id: A0A0S2K0F2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

161398:PP2015 RS14865
gene id: 161398:PP2015_RS14865
uniprot id: A0A0S2K579
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

161398:PP2015 RS09795
gene id: 161398:PP2015_RS09795
uniprot id: A0A0S2K2Y7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

161398:PP2015 RS04285
gene id: 161398:PP2015_RS04285
uniprot id: A0A0S2K006
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

161398:PP2015 RS11170
gene id: 161398:PP2015_RS11170
uniprot id: A0A0S2K336
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS08685
gene id: 161398:PP2015_RS08685
uniprot id: A0A0S2K2N5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS21125
gene id: 161398:PP2015_RS21125
uniprot id: A0A0S2K8D3
names: Similarity
messages: Belongs to the cytochrome b562 family.

161398:PP2015 RS14125
gene id: 161398:PP2015_RS14125
uniprot id: A0A0S2K5D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

161398:PP2015 RS12855
gene id: 161398:PP2015_RS12855
uniprot id: A0A0S2K3F5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

161398:PP2015 RS19420
gene id: 161398:PP2015_RS19420
uniprot id: A0A0S2K7J4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS07250
gene id: 161398:PP2015_RS07250
uniprot id: A0A0S2K0L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

161398:PP2015 RS07750
gene id: 161398:PP2015_RS07750
uniprot id: A0A0S2K1T7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS13915
gene id: 161398:PP2015_RS13915
uniprot id: A0A0S2K400
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

161398:PP2015 RS15050
gene id: 161398:PP2015_RS15050
uniprot id: A0A0S2K5T6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

161398:PP2015 RS14525
gene id: 161398:PP2015_RS14525
uniprot id: A0A0S2K4Q8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

161398:PP2015 RS04815
gene id: 161398:PP2015_RS04815
uniprot id: A0A0S2JZ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

161398:PP2015 RS01520
gene id: 161398:PP2015_RS01520
uniprot id: A0A0S2JYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

161398:PP2015 RS00225
gene id: 161398:PP2015_RS00225
uniprot id: A0A0S2JWY1
names: Similarity
messages: Belongs to the UPF0502 family.

161398:PP2015 RS13870
gene id: 161398:PP2015_RS13870
uniprot id: A0A0S2K4G7
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

161398:PP2015 RS03880
gene id: 161398:PP2015_RS03880
uniprot id: A0A0S2JYP1
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

161398:PP2015 RS09905
gene id: 161398:PP2015_RS09905
uniprot id: A0A0S2K315
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

161398:PP2015 RS02500
gene id: 161398:PP2015_RS02500
uniprot id: A0A0S2JYE2
names: Similarity
messages: Belongs to the UPF0111 family.

161398:PP2015 RS00880
gene id: 161398:PP2015_RS00880
uniprot id: A0A0S2JXK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

161398:PP2015 RS13925
gene id: 161398:PP2015_RS13925
uniprot id: A0A0S2K4E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

161398:PP2015 RS14730
gene id: 161398:PP2015_RS14730
uniprot id: A0A0S2K5Q0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS10370
gene id: 161398:PP2015_RS10370
uniprot id: A0A0S2K3B6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

161398:PP2015 RS15000
gene id: 161398:PP2015_RS15000
uniprot id: A0A0S2K5T9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS19540
gene id: 161398:PP2015_RS19540
uniprot id: A0A0S2K8G2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

161398:PP2015 RS06270
gene id: 161398:PP2015_RS06270
uniprot id: A0A0S2K0Z3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

161398:PP2015 RS12600
gene id: 161398:PP2015_RS12600
uniprot id: A0A0S2K4I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

161398:PP2015 RS12695
gene id: 161398:PP2015_RS12695
uniprot id: A0A0S2K3C3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

161398:PP2015 RS01860
gene id: 161398:PP2015_RS01860
uniprot id: A0A0S2JYM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

161398:PP2015 RS04910
gene id: 161398:PP2015_RS04910
uniprot id: A0A0S2K0B8
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

161398:PP2015 RS00010
gene id: 161398:PP2015_RS00010
uniprot id: A0A0S2JXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

161398:PP2015 RS11690
gene id: 161398:PP2015_RS11690
uniprot id: A0A0S2K3B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

161398:PP2015 RS10490
gene id: 161398:PP2015_RS10490
uniprot id: A0A0S2K3C4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS09185
gene id: 161398:PP2015_RS09185
uniprot id: A0A0S2K2Z7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

161398:PP2015 RS09855
gene id: 161398:PP2015_RS09855
uniprot id: A0A0S2K289
names: Subcellular Location Annotation
messages: Cytoplasm

161398:PP2015 RS05050
gene id: 161398:PP2015_RS05050
uniprot id: A0A0S2JZE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

161398:PP2015 RS02680
gene id: 161398:PP2015_RS02680
uniprot id: A0A0S2JYW9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

161398:PP2015 RS17530
gene id: 161398:PP2015_RS17530
uniprot id: A0A0S2K6J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

161398:PP2015 RS04900
gene id: 161398:PP2015_RS04900
uniprot id: A0A4Q7INN8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS17565
gene id: 161398:PP2015_RS17565
uniprot id: A0A0S2K781
names: Similarity
messages: Belongs to the elongation factor P family.

161398:PP2015 RS18870
gene id: 161398:PP2015_RS18870
uniprot id: A0A0S2K734
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS17885
gene id: 161398:PP2015_RS17885
uniprot id: A0A0S2K7M1
names: Similarity
messages: Belongs to the citrate synthase family.

161398:PP2015 RS01310
gene id: 161398:PP2015_RS01310
uniprot id: A0A0S2JXN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

161398:PP2015 RS07730
gene id: 161398:PP2015_RS07730
uniprot id: A0A0S2K0W0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

161398:PP2015 RS19830
gene id: 161398:PP2015_RS19830
uniprot id: A0A0S2K7I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS17770
gene id: 161398:PP2015_RS17770
uniprot id: A0A0S2K6J1
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS14735
gene id: 161398:PP2015_RS14735
uniprot id: A0A0S2K514
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

161398:PP2015 RS05040
gene id: 161398:PP2015_RS05040
uniprot id: A0A0S2K0D6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

161398:PP2015 RS08065
gene id: 161398:PP2015_RS08065
uniprot id: A0A0S2K228
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS02185
gene id: 161398:PP2015_RS02185
uniprot id: A0A0S2JYS0
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS05275
gene id: 161398:PP2015_RS05275
uniprot id: A0A0S2JZE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

161398:PP2015 RS13890
gene id: 161398:PP2015_RS13890
uniprot id: A0A0S2K568
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

161398:PP2015 RS13445
gene id: 161398:PP2015_RS13445
uniprot id: A0A0S2K4A7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

161398:PP2015 RS09925
gene id: 161398:PP2015_RS09925
uniprot id: A0A0S2K2L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

161398:PP2015 RS17025
gene id: 161398:PP2015_RS17025
uniprot id: A0A0S2K5M4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

161398:PP2015 RS09155
gene id: 161398:PP2015_RS09155
uniprot id: A0A0S2K1V9
names: Similarity
messages: Belongs to the asparagine synthetase family.

161398:PP2015 RS07555
gene id: 161398:PP2015_RS07555
uniprot id: A0A0S2K142
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

161398:PP2015 RS13885
gene id: 161398:PP2015_RS13885
uniprot id: A0A0S2K575
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

161398:PP2015 RS12640
gene id: 161398:PP2015_RS12640
uniprot id: A0A0S2K3S2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

161398:PP2015 RS16410
gene id: 161398:PP2015_RS16410
uniprot id: A0A0S2K6R4
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

161398:PP2015 RS09615
gene id: 161398:PP2015_RS09615
uniprot id: A0A0S2K2W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

161398:PP2015 RS12745
gene id: 161398:PP2015_RS12745
uniprot id: A0A0S2K3Y1
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

161398:PP2015 RS03600
gene id: 161398:PP2015_RS03600
uniprot id: A0A0S2JYY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

161398:PP2015 RS02605
gene id: 161398:PP2015_RS02605
uniprot id: A0A0S2JYF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

161398:PP2015 RS14920
gene id: 161398:PP2015_RS14920
uniprot id: A0A0S2K5S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

161398:PP2015 RS13365
gene id: 161398:PP2015_RS13365
uniprot id: A0A0S2K491
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

161398:PP2015 RS01305
gene id: 161398:PP2015_RS01305
uniprot id: A0A0S2JXA5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

161398:PP2015 RS18820
gene id: 161398:PP2015_RS18820
uniprot id: A0A0S2K840
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS08835
gene id: 161398:PP2015_RS08835
uniprot id: A0A0S2K1X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

161398:PP2015 RS00560
gene id: 161398:PP2015_RS00560
uniprot id: A0A0S2JWX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

161398:PP2015 RS11630
gene id: 161398:PP2015_RS11630
uniprot id: A0A0S2K409
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

161398:PP2015 RS02480
gene id: 161398:PP2015_RS02480
uniprot id: A0A0S2JYA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

161398:PP2015 RS17190
gene id: 161398:PP2015_RS17190
uniprot id: A0A0S2K5R7
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS13880
gene id: 161398:PP2015_RS13880
uniprot id: A0A0S2K571
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

161398:PP2015 RS13685
gene id: 161398:PP2015_RS13685
uniprot id: A0A0S2K497
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

161398:PP2015 RS06945
gene id: 161398:PP2015_RS06945
uniprot id: A0A0S2K1G1
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

161398:PP2015 RS00955
gene id: 161398:PP2015_RS00955
uniprot id: A0A0S2JY19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

161398:PP2015 RS20980
gene id: 161398:PP2015_RS20980
uniprot id: A0A0S2K8P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

161398:PP2015 RS05045
gene id: 161398:PP2015_RS05045
uniprot id: A0A0S2K0B0
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

161398:PP2015 RS21470
gene id: 161398:PP2015_RS21470
uniprot id: A0A0S2K8L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

161398:PP2015 RS09290
gene id: 161398:PP2015_RS09290
uniprot id: A0A0S2K2P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmI family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.

161398:PP2015 RS19170
gene id: 161398:PP2015_RS19170
uniprot id: A0A0S2K735
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS06565
gene id: 161398:PP2015_RS06565
uniprot id: A0A0S2K0J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

161398:PP2015 RS01680
gene id: 161398:PP2015_RS01680
uniprot id: A0A0S2JYG5
names: Similarity
messages: Belongs to the UPF0102 family.

161398:PP2015 RS17330
gene id: 161398:PP2015_RS17330
uniprot id: A0A0S2K6D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

161398:PP2015 RS03595
gene id: 161398:PP2015_RS03595
uniprot id: A0A0S2JYY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS02935
gene id: 161398:PP2015_RS02935
uniprot id: A0A0S2JY64
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

161398:PP2015 RS02925
gene id: 161398:PP2015_RS02925
uniprot id: A0A0S2JZ15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

161398:PP2015 RS05950
gene id: 161398:PP2015_RS05950
uniprot id: A0A0S2JZZ9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS07560
gene id: 161398:PP2015_RS07560
uniprot id: A0A0S2K1Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

161398:PP2015 RS06865
gene id: 161398:PP2015_RS06865
uniprot id: A0A0S2K1B3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

161398:PP2015 RS02685
gene id: 161398:PP2015_RS02685
uniprot id: A0A0S2JYG8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

161398:PP2015 RS08810
gene id: 161398:PP2015_RS08810
uniprot id: A0A0S2K1Q7
names: Similarity
messages: Belongs to the proline racemase family.

161398:PP2015 RS21485
gene id: 161398:PP2015_RS21485
uniprot id: A0A0S2K8Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

161398:PP2015 RS10640
gene id: 161398:PP2015_RS10640
uniprot id: A0A0S2K2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

161398:PP2015 RS05340
gene id: 161398:PP2015_RS05340
uniprot id: A0A0S2JZU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS21380
gene id: 161398:PP2015_RS21380
uniprot id: A0A0S2K8U0
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

161398:PP2015 RS11650
gene id: 161398:PP2015_RS11650
uniprot id: A0A0S2K412
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

161398:PP2015 RS15925
gene id: 161398:PP2015_RS15925
uniprot id: A0A0S2K5I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

161398:PP2015 RS04985
gene id: 161398:PP2015_RS04985
uniprot id: A0A0S2K0F3
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

161398:PP2015 RS18610
gene id: 161398:PP2015_RS18610
uniprot id: A0A0S2K6R0
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS19040
gene id: 161398:PP2015_RS19040
uniprot id: A0A0S2K7Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

161398:PP2015 RS10135
gene id: 161398:PP2015_RS10135
uniprot id: A0A0S2K3F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS11645
gene id: 161398:PP2015_RS11645
uniprot id: A0A0S2K4D1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

161398:PP2015 RS08510
gene id: 161398:PP2015_RS08510
uniprot id: A0A0S2K1Q5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

161398:PP2015 RS07545
gene id: 161398:PP2015_RS07545
uniprot id: A0A0S2K118
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

161398:PP2015 RS02765
gene id: 161398:PP2015_RS02765
uniprot id: A0A0S2JYJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

161398:PP2015 RS15620
gene id: 161398:PP2015_RS15620
uniprot id: A0A0S2K564
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

161398:PP2015 RS05295
gene id: 161398:PP2015_RS05295
uniprot id: A0A0S2K0H6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

161398:PP2015 RS13695
gene id: 161398:PP2015_RS13695
uniprot id: A0A0S2K4Z9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

161398:PP2015 RS21035
gene id: 161398:PP2015_RS21035
uniprot id: A0A0S2K977
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS08030
gene id: 161398:PP2015_RS08030
uniprot id: A0A0S2K195
names: Similarity
messages: Belongs to the YciI family.

161398:PP2015 RS15885
gene id: 161398:PP2015_RS15885
uniprot id: A0A0S2K5Q9
names: Similarity
messages: Belongs to the GSP N family.

161398:PP2015 RS07915
gene id: 161398:PP2015_RS07915
uniprot id: A0A0S2K1X1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

161398:PP2015 RS19495
gene id: 161398:PP2015_RS19495
uniprot id: A0A0S2K798
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

161398:PP2015 RS02725
gene id: 161398:PP2015_RS02725
uniprot id: A0A0S2JZ49
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

161398:PP2015 RS07550
gene id: 161398:PP2015_RS07550
uniprot id: A0A0S2K0Z5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

161398:PP2015 RS04635
gene id: 161398:PP2015_RS04635
uniprot id: A0A0S2JZH5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

161398:PP2015 RS08705
gene id: 161398:PP2015_RS08705
uniprot id: A0A0S2K1Q6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

161398:PP2015 RS00565
gene id: 161398:PP2015_RS00565
uniprot id: A0A0S2JX86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS01900
gene id: 161398:PP2015_RS01900
uniprot id: A0A0S2JXN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

161398:PP2015 RS12570
gene id: 161398:PP2015_RS12570
uniprot id: A0A0S2K3K2
names: Similarity
messages: Belongs to the Smp family.

161398:PP2015 RS01420
gene id: 161398:PP2015_RS01420
uniprot id: A0A0S2JXJ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS02805
gene id: 161398:PP2015_RS02805
uniprot id: A0A0S2JZB3
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

161398:PP2015 RS04940
gene id: 161398:PP2015_RS04940
uniprot id: A0A0S2JZP7
names: Similarity
messages: Belongs to the type III secretion exporter family.

161398:PP2015 RS16810
gene id: 161398:PP2015_RS16810
uniprot id: A0A0S2K681
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS15370
gene id: 161398:PP2015_RS15370
uniprot id: A0A0S2K591
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

161398:PP2015 RS15955
gene id: 161398:PP2015_RS15955
uniprot id: A0A0S2K519
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

161398:PP2015 RS02560
gene id: 161398:PP2015_RS02560
uniprot id: A0A0S2JYB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

161398:PP2015 RS07540
gene id: 161398:PP2015_RS07540
uniprot id: A0A0S2K0H8
names: Subcellular Location Annotation
messages: Cytoplasm

161398:PP2015 RS03235
gene id: 161398:PP2015_RS03235
uniprot id: A0A0S2JYR3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS00025
gene id: 161398:PP2015_RS00025
uniprot id: A0A0S2JWM8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

161398:PP2015 RS07060
gene id: 161398:PP2015_RS07060
uniprot id: A0A0S2K0T1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

161398:PP2015 RS07695
gene id: 161398:PP2015_RS07695
uniprot id: A0A0S2K1E5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

161398:PP2015 RS04415
gene id: 161398:PP2015_RS04415
uniprot id: A0A0S2JZB8
names: Similarity
messages: Belongs to the P(II) protein family.

161398:PP2015 RS11050
gene id: 161398:PP2015_RS11050
uniprot id: A0A0S2K3N7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily.

161398:PP2015 RS20525
gene id: 161398:PP2015_RS20525
uniprot id: A0A0S2K8Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

161398:PP2015 RS12515
gene id: 161398:PP2015_RS12515
uniprot id: A0A0S2K4G9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

161398:PP2015 RS10830
gene id: 161398:PP2015_RS10830
uniprot id: A0A0S2K3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS01850
gene id: 161398:PP2015_RS01850
uniprot id: A0A0S2JXN2
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

161398:PP2015 RS15195
gene id: 161398:PP2015_RS15195
uniprot id: A0A0S2K5C9
names: Subcellular Location Annotation
messages: Secreted

161398:PP2015 RS11710
gene id: 161398:PP2015_RS11710
uniprot id: A0A0S2K422
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

161398:PP2015 RS11670
gene id: 161398:PP2015_RS11670
uniprot id: A0A0S2K2S0
names: Similarity
messages: Belongs to the Skp family.

161398:PP2015 RS07755
gene id: 161398:PP2015_RS07755
uniprot id: A0A0S2K1S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

161398:PP2015 RS20305
gene id: 161398:PP2015_RS20305
uniprot id: A0A0S2K896
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

161398:PP2015 RS08820
gene id: 161398:PP2015_RS08820
uniprot id: A0A0S2K2G0
names: Similarity
messages: Belongs to the peptidase M24B family.

161398:PP2015 RS04335
gene id: 161398:PP2015_RS04335
uniprot id: A0A0S2JZA6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

161398:PP2015 RS15900
gene id: 161398:PP2015_RS15900
uniprot id: A0A0S2K5E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS15290
gene id: 161398:PP2015_RS15290
uniprot id: A0A0S2K576
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS04310
gene id: 161398:PP2015_RS04310
uniprot id: A0A0S2K015
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

161398:PP2015 RS06760
gene id: 161398:PP2015_RS06760
uniprot id: A0A0S2K0T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS15600
gene id: 161398:PP2015_RS15600
uniprot id: A0A0S2K5A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS21030
gene id: 161398:PP2015_RS21030
uniprot id: A0A0S2K959
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

161398:PP2015 RS20690
gene id: 161398:PP2015_RS20690
uniprot id: A0A0S2K931
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

161398:PP2015 RS04360
gene id: 161398:PP2015_RS04360
uniprot id: A0A0S2K023
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

161398:PP2015 RS02870
gene id: 161398:PP2015_RS02870
uniprot id: A0A0S2JYE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

161398:PP2015 RS14785
gene id: 161398:PP2015_RS14785
uniprot id: A0A0S2K4H1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS13930
gene id: 161398:PP2015_RS13930
uniprot id: A0A0S2K4M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

161398:PP2015 RS16170
gene id: 161398:PP2015_RS16170
uniprot id: A0A0S2K5M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

161398:PP2015 RS16415
gene id: 161398:PP2015_RS16415
uniprot id: A0A0S2K5K6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS04505
gene id: 161398:PP2015_RS04505
uniprot id: A0A0S2JZD5
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

161398:PP2015 RS00895
gene id: 161398:PP2015_RS00895
uniprot id: A0A0S2JXG5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

161398:PP2015 RS04455
gene id: 161398:PP2015_RS04455
uniprot id: A0A0S2K004
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS00090
gene id: 161398:PP2015_RS00090
uniprot id: A0A0S2JXH6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

161398:PP2015 RS02905
gene id: 161398:PP2015_RS02905
uniprot id: A0A0S2JYM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

161398:PP2015 RS17730
gene id: 161398:PP2015_RS17730
uniprot id: A0A0S2K7B8
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS10295
gene id: 161398:PP2015_RS10295
uniprot id: A0A0S2K2L1
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

161398:PP2015 RS14890
gene id: 161398:PP2015_RS14890
uniprot id: A0A0S2K5Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

161398:PP2015 RS04350
gene id: 161398:PP2015_RS04350
uniprot id: A0A0S2JZD6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

161398:PP2015 RS04885
gene id: 161398:PP2015_RS04885
uniprot id: A0A0S2K0B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

161398:PP2015 RS17915
gene id: 161398:PP2015_RS17915
uniprot id: A0A0S2K713
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

161398:PP2015 RS03885
gene id: 161398:PP2015_RS03885
uniprot id: A0A0S2JYW0
names: Caution
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS11675
gene id: 161398:PP2015_RS11675
uniprot id: A0A0S2K3W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

161398:PP2015 RS10010
gene id: 161398:PP2015_RS10010
uniprot id: A0A0S2K1U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

161398:PP2015 RS16470
gene id: 161398:PP2015_RS16470
uniprot id: A0A0S2K5B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

161398:PP2015 RS09410
gene id: 161398:PP2015_RS09410
uniprot id: A0A0S2K284
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

161398:PP2015 RS08530
gene id: 161398:PP2015_RS08530
uniprot id: A0A0S2K1R4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

161398:PP2015 RS08505
gene id: 161398:PP2015_RS08505
uniprot id: A0A0S2K1I9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

161398:PP2015 RS03590
gene id: 161398:PP2015_RS03590
uniprot id: A0A0S2JYJ2
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

161398:PP2015 RS07520
gene id: 161398:PP2015_RS07520
uniprot id: A0A0S2K115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

161398:PP2015 RS14215
gene id: 161398:PP2015_RS14215
uniprot id: A0A0S2K4N2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

161398:PP2015 RS11295
gene id: 161398:PP2015_RS11295
uniprot id: A0A0S2K3U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

161398:PP2015 RS09985
gene id: 161398:PP2015_RS09985
uniprot id: A0A0S2K331
names: Subunit
messages: Homodimer.

161398:PP2015 RS12105
gene id: 161398:PP2015_RS12105
uniprot id: A0A0S2K494
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

161398:PP2015 RS00390
gene id: 161398:PP2015_RS00390
uniprot id: A0A0S2JX84
names: Similarity
messages: Belongs to the thioredoxin family.

161398:PP2015 RS06735
gene id: 161398:PP2015_RS06735
uniprot id: A0A0S2K0J3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS16155
gene id: 161398:PP2015_RS16155
uniprot id: A0A0S2K6D8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

161398:PP2015 RS08405
gene id: 161398:PP2015_RS08405
uniprot id: A0A0S2K208
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS08915
gene id: 161398:PP2015_RS08915
uniprot id: A0A0S2K1Z3
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS18210
gene id: 161398:PP2015_RS18210
uniprot id: A0A0S2K6F5
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS12020
gene id: 161398:PP2015_RS12020
uniprot id: A0A0S2K4J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS11880
gene id: 161398:PP2015_RS11880
uniprot id: A0A0S2K3H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

161398:PP2015 RS18495
gene id: 161398:PP2015_RS18495
uniprot id: A0A0S2K6P9
names: Similarity
messages: Belongs to the PspA/IM30 family.

161398:PP2015 RS16530
gene id: 161398:PP2015_RS16530
uniprot id: A0A0S2K5Z8
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

161398:PP2015 RS15610
gene id: 161398:PP2015_RS15610
uniprot id: A0A0S2K631
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

161398:PP2015 RS14455
gene id: 161398:PP2015_RS14455
uniprot id: A0A0S2K5G4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

161398:PP2015 RS16910
gene id: 161398:PP2015_RS16910
uniprot id: A0A0S2K5U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

161398:PP2015 RS05290
gene id: 161398:PP2015_RS05290
uniprot id: A0A0S2JZQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

161398:PP2015 RS13725
gene id: 161398:PP2015_RS13725
uniprot id: A0A0S2K544
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

161398:PP2015 RS13430
gene id: 161398:PP2015_RS13430
uniprot id: A0A0S2K4Y6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

161398:PP2015 RS16625
gene id: 161398:PP2015_RS16625
uniprot id: A0A0S2K678
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS14120
gene id: 161398:PP2015_RS14120
uniprot id: A0A0S2K5D8
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS14230
gene id: 161398:PP2015_RS14230
uniprot id: A0A0S2K5F2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

161398:PP2015 RS16190
gene id: 161398:PP2015_RS16190
uniprot id: A0A0S2K6C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

161398:PP2015 RS13200
gene id: 161398:PP2015_RS13200
uniprot id: A0A0S2K4V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

161398:PP2015 RS02370
gene id: 161398:PP2015_RS02370
uniprot id: A0A0S2JXV9
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

161398:PP2015 RS22040
gene id: 161398:PP2015_RS22040
uniprot id: A0A0S2K343
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161398:PP2015 RS01365
gene id: 161398:PP2015_RS01365
uniprot id: A0A0S2JXT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS04430
gene id: 161398:PP2015_RS04430
uniprot id: A0A0S2JZG1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

161398:PP2015 RS03685
gene id: 161398:PP2015_RS03685
uniprot id: A0A0S2JYL4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS07835
gene id: 161398:PP2015_RS07835
uniprot id: A0A0S2K1V8
names: Similarity
messages: Belongs to the AlaDH/PNT family.

161398:PP2015 RS05145
gene id: 161398:PP2015_RS05145
uniprot id: A0A0S2JZT5
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

161398:PP2015 RS20340
gene id: 161398:PP2015_RS20340
uniprot id: A0A0S2K901
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS07495
gene id: 161398:PP2015_RS07495
uniprot id: A0A0S2K178
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

161398:PP2015 RS12905
gene id: 161398:PP2015_RS12905
uniprot id: A0A0S2K3X2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

161398:PP2015 RS16450
gene id: 161398:PP2015_RS16450
uniprot id: A0A0S2K5Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

161398:PP2015 RS00030
gene id: 161398:PP2015_RS00030
uniprot id: A0A0S2JWZ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

161398:PP2015 RS07315
gene id: 161398:PP2015_RS07315
uniprot id: A0A0S2K0Z4
names: Similarity
messages: Belongs to the UPF0145 family.

161398:PP2015 RS20035
gene id: 161398:PP2015_RS20035
uniprot id: A0A0S2K8R9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS05935
gene id: 161398:PP2015_RS05935
uniprot id: A0A0S2K037
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

161398:PP2015 RS20995
gene id: 161398:PP2015_RS20995
uniprot id: A0A0S2K8B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

161398:PP2015 RS04625
gene id: 161398:PP2015_RS04625
uniprot id: A0A0S2JZ27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

161398:PP2015 RS07430
gene id: 161398:PP2015_RS07430
uniprot id: A0A0S2K1M5
names: Similarity
messages: Belongs to the peptidase S9C family.

161398:PP2015 RS06830
gene id: 161398:PP2015_RS06830
uniprot id: A0A0S2K1A8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

161398:PP2015 RS00105
gene id: 161398:PP2015_RS00105
uniprot id: A0A0S2JWP6
names: Similarity
messages: Belongs to the DprA/Smf family.

161398:PP2015 RS09990
gene id: 161398:PP2015_RS09990
uniprot id: A0A0S2K2F0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

161398:PP2015 RS15325
gene id: 161398:PP2015_RS15325
uniprot id: A0A0S2K5S1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS05610
gene id: 161398:PP2015_RS05610
uniprot id: A0A0S2JZH8
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

161398:PP2015 RS12405
gene id: 161398:PP2015_RS12405
uniprot id: A0A0S2K4E9
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

161398:PP2015 RS05110
gene id: 161398:PP2015_RS05110
uniprot id: A0A0S2JZA3
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

161398:PP2015 RS15895
gene id: 161398:PP2015_RS15895
uniprot id: A0A0S2K5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

161398:PP2015 RS13605
gene id: 161398:PP2015_RS13605
uniprot id: A0A4Q7IPG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS08385
gene id: 161398:PP2015_RS08385
uniprot id: A0A0S2K259
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

161398:PP2015 RS02770
gene id: 161398:PP2015_RS02770
uniprot id: A0A0S2JY35
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

161398:PP2015 RS10740
gene id: 161398:PP2015_RS10740
uniprot id: A0A0S2K2J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

161398:PP2015 RS04870
gene id: 161398:PP2015_RS04870
uniprot id: A0A0S2JZL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

161398:PP2015 RS09910
gene id: 161398:PP2015_RS09910
uniprot id: A0A0S2K2D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

161398:PP2015 RS13335
gene id: 161398:PP2015_RS13335
uniprot id: A0A0S2K4W2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS00590
gene id: 161398:PP2015_RS00590
uniprot id: A0A0S2JXJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS13385
gene id: 161398:PP2015_RS13385
uniprot id: A0A0S2K3Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

161398:PP2015 RS03760
gene id: 161398:PP2015_RS03760
uniprot id: A0A0S2JZ14
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

161398:PP2015 RS16460
gene id: 161398:PP2015_RS16460
uniprot id: A0A0S2K687
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

161398:PP2015 RS11930
gene id: 161398:PP2015_RS11930
uniprot id: A0A0S2K366
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

161398:PP2015 RS17195
gene id: 161398:PP2015_RS17195
uniprot id: A0A0S2K666
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

161398:PP2015 RS18875
gene id: 161398:PP2015_RS18875
uniprot id: A0A0S2K7B7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

161398:PP2015 RS02630
gene id: 161398:PP2015_RS02630
uniprot id: A0A0S2JY88
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

161398:PP2015 RS01645
gene id: 161398:PP2015_RS01645
uniprot id: A0A0S2JXH4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

161398:PP2015 RS02640
gene id: 161398:PP2015_RS02640
uniprot id: A0A0S2JYC6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

161398:PP2015 RS07330
gene id: 161398:PP2015_RS07330
uniprot id: A0A0S2K0N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

161398:PP2015 RS05535
gene id: 161398:PP2015_RS05535
uniprot id: A0A0S2JZZ5
names: Subcellular Location Annotation
messages: Cell inner membrane

161398:PP2015 RS17865
gene id: 161398:PP2015_RS17865
uniprot id: A0A4Q7IP71
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS11640
gene id: 161398:PP2015_RS11640
uniprot id: A0A0S2K3D3
names: Subcellular Location Annotation
messages: Cytoplasm

161398:PP2015 RS00960
gene id: 161398:PP2015_RS00960
uniprot id: A0A0S2JXL8
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

161398:PP2015 RS13355
gene id: 161398:PP2015_RS13355
uniprot id: A0A0S2K4X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS17385
gene id: 161398:PP2015_RS17385
uniprot id: A0A0S2K637
names: Cofactor
messages: Can also use Mn(2+) ion.

161398:PP2015 RS21360
gene id: 161398:PP2015_RS21360
uniprot id: A0A0S2K9E1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS07065
gene id: 161398:PP2015_RS07065
uniprot id: A0A0S2K0Q6
names: Similarity
messages: Belongs to the ArsC family.

161398:PP2015 RS13960
gene id: 161398:PP2015_RS13960
uniprot id: A0A0S2K588
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

161398:PP2015 RS18665
gene id: 161398:PP2015_RS18665
uniprot id: A0A0S2K814
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

161398:PP2015 RS08765
gene id: 161398:PP2015_RS08765
uniprot id: A0A0S2K2Q9
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

161398:PP2015 RS02760
gene id: 161398:PP2015_RS02760
uniprot id: A0A0S2JYY8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

161398:PP2015 RS08910
gene id: 161398:PP2015_RS08910
uniprot id: A0A0S2K1J5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

161398:PP2015 RS07910
gene id: 161398:PP2015_RS07910
uniprot id: A0A0S2K202
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

161398:PP2015 RS06040
gene id: 161398:PP2015_RS06040
uniprot id: A0A0S2K135
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

161398:PP2015 RS08720
gene id: 161398:PP2015_RS08720
uniprot id: A0A0S2K1Z9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

161398:PP2015 RS13320
gene id: 161398:PP2015_RS13320
uniprot id: A0A0S2K436
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS14585
gene id: 161398:PP2015_RS14585
uniprot id: A0A0S2K5C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

161398:PP2015 RS16750
gene id: 161398:PP2015_RS16750
uniprot id: A0A0S2K5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

161398:PP2015 RS08850
gene id: 161398:PP2015_RS08850
uniprot id: A0A0S2K2F8
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

161398:PP2015 RS00700
gene id: 161398:PP2015_RS00700
uniprot id: A0A0S2JXS6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS19250
gene id: 161398:PP2015_RS19250
uniprot id: A0A0S2K7Q9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

161398:PP2015 RS04345
gene id: 161398:PP2015_RS04345
uniprot id: A0A0S2JZ50
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

161398:PP2015 RS10270
gene id: 161398:PP2015_RS10270
uniprot id: A0A0S2K297
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

161398:PP2015 RS07855
gene id: 161398:PP2015_RS07855
uniprot id: A0A0S2K1P5
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

161398:PP2015 RS18080
gene id: 161398:PP2015_RS18080
uniprot id: A0A0S2K6V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

161398:PP2015 RS10700
gene id: 161398:PP2015_RS10700
uniprot id: A0A0S2K3B9
names: Subcellular Location Annotation
messages: Cell inner membrane

161398:PP2015 RS07085
gene id: 161398:PP2015_RS07085
uniprot id: A0A0S2K0I6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

161398:PP2015 RS19275
gene id: 161398:PP2015_RS19275
uniprot id: A0A0S2K826
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS20600
gene id: 161398:PP2015_RS20600
uniprot id: A0A0S2K7Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

161398:PP2015 RS09235
gene id: 161398:PP2015_RS09235
uniprot id: A0A0S2K1Y5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161398:PP2015 RS01785
gene id: 161398:PP2015_RS01785
uniprot id: A0A0S2JYI7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS03270
gene id: 161398:PP2015_RS03270
uniprot id: A0A0S2JYS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

161398:PP2015 RS07765
gene id: 161398:PP2015_RS07765
uniprot id: A0A0S2K0J0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

161398:PP2015 RS13205
gene id: 161398:PP2015_RS13205
uniprot id: A0A0S2K4W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

161398:PP2015 RS01055
gene id: 161398:PP2015_RS01055
uniprot id: A0A0S2JXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

161398:PP2015 RS19815
gene id: 161398:PP2015_RS19815
uniprot id: A0A0S2K7G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

161398:PP2015 RS06985
gene id: 161398:PP2015_RS06985
uniprot id: A0A0S2K0N9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

161398:PP2015 RS21170
gene id: 161398:PP2015_RS21170
uniprot id: A0A0S2K935
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

161398:PP2015 RS16290
gene id: 161398:PP2015_RS16290
uniprot id: A0A0S2K582
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

161398:PP2015 RS17605
gene id: 161398:PP2015_RS17605
uniprot id: A0A0S2K6G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS04845
gene id: 161398:PP2015_RS04845
uniprot id: A0A0S2JZK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

161398:PP2015 RS01930
gene id: 161398:PP2015_RS01930
uniprot id: A0A0S2JXP8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

161398:PP2015 RS17240
gene id: 161398:PP2015_RS17240
uniprot id: A0A0S2K724
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

161398:PP2015 RS15840
gene id: 161398:PP2015_RS15840
uniprot id: A0A0S2K592
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

161398:PP2015 RS18390
gene id: 161398:PP2015_RS18390
uniprot id: A0A0S2K6V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

161398:PP2015 RS19775
gene id: 161398:PP2015_RS19775
uniprot id: A0A0S2K8Q2
names: Similarity
messages: Belongs to the NodU/CmcH family.

161398:PP2015 RS15475
gene id: 161398:PP2015_RS15475
uniprot id: A0A0S2K5F1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

161398:PP2015 RS08745
gene id: 161398:PP2015_RS08745
uniprot id: A0A0S2K2E0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

161398:PP2015 RS10965
gene id: 161398:PP2015_RS10965
uniprot id: A0A0S2K347
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS14550
gene id: 161398:PP2015_RS14550
uniprot id: A0A0S2K4U2
names: Similarity
messages: Belongs to the group II decarboxylase family.

161398:PP2015 RS00230
gene id: 161398:PP2015_RS00230
uniprot id: A0A0S2JX50
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

161398:PP2015 RS03980
gene id: 161398:PP2015_RS03980
uniprot id: A0A0S2JZU1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS09040
gene id: 161398:PP2015_RS09040
uniprot id: A0A0S2K196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

161398:PP2015 RS01880
gene id: 161398:PP2015_RS01880
uniprot id: A0A0S2JY13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

161398:PP2015 RS06275
gene id: 161398:PP2015_RS06275
uniprot id: A0A5R9Q4D1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS19230
gene id: 161398:PP2015_RS19230
uniprot id: A0A0S2K7X6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

161398:PP2015 RS09590
gene id: 161398:PP2015_RS09590
uniprot id: A0A0S2K1W9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

161398:PP2015 RS01160
gene id: 161398:PP2015_RS01160
uniprot id: A0A0S2JXA3
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS00515
gene id: 161398:PP2015_RS00515
uniprot id: A0A0S2JXY1
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS01000
gene id: 161398:PP2015_RS01000
uniprot id: A0A0S2JXJ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS01835
gene id: 161398:PP2015_RS01835
uniprot id: A0A0S2JXX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

161398:PP2015 RS16010
gene id: 161398:PP2015_RS16010
uniprot id: A0A0S2K6L7
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

161398:PP2015 RS21975
gene id: 161398:PP2015_RS21975
uniprot id: A0A0S2K881
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

161398:PP2015 RS04775
gene id: 161398:PP2015_RS04775
uniprot id: A0A0S2JZS5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

161398:PP2015 RS00890
gene id: 161398:PP2015_RS00890
uniprot id: A0A0S2JXE6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

161398:PP2015 RS04105
gene id: 161398:PP2015_RS04105
uniprot id: A0A0S2JYS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS14090
gene id: 161398:PP2015_RS14090
uniprot id: A0A0S2K4S4
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

161398:PP2015 RS03045
gene id: 161398:PP2015_RS03045
uniprot id: A0A0S2JYH1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS13730
gene id: 161398:PP2015_RS13730
uniprot id: A0A0S2K537
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

161398:PP2015 RS02620
gene id: 161398:PP2015_RS02620
uniprot id: A0A0S2JYB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

161398:PP2015 RS15850
gene id: 161398:PP2015_RS15850
uniprot id: A0A0S2K6G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

161398:PP2015 RS21275
gene id: 161398:PP2015_RS21275
uniprot id: A0A0S2K9A9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

161398:PP2015 RS09405
gene id: 161398:PP2015_RS09405
uniprot id: A0A0S2K207
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

161398:PP2015 RS06020
gene id: 161398:PP2015_RS06020
uniprot id: A0A0S2K0X1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS01570
gene id: 161398:PP2015_RS01570
uniprot id: A0A0S2JXR3
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

161398:PP2015 RS01385
gene id: 161398:PP2015_RS01385
uniprot id: A0A0S2JY96
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161398:PP2015 RS08140
gene id: 161398:PP2015_RS08140
uniprot id: A0A0S2K1I5
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS06235
gene id: 161398:PP2015_RS06235
uniprot id: A0A4Q7IPZ3
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS09805
gene id: 161398:PP2015_RS09805
uniprot id: A0A0S2K2E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

161398:PP2015 RS02790
gene id: 161398:PP2015_RS02790
uniprot id: A0A0S2JYB8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

161398:PP2015 RS02345
gene id: 161398:PP2015_RS02345
uniprot id: A0A0S2JYV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS13635
gene id: 161398:PP2015_RS13635
uniprot id: A0A0S2K4C1
names: Similarity
messages: Belongs to the UPF0250 family.

161398:PP2015 RS03425
gene id: 161398:PP2015_RS03425
uniprot id: A0A0S2JYG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.

161398:PP2015 RS09055
gene id: 161398:PP2015_RS09055
uniprot id: A0A0S2K1C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

161398:PP2015 RS14885
gene id: 161398:PP2015_RS14885
uniprot id: A0A0S2K569
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

161398:PP2015 RS01295
gene id: 161398:PP2015_RS01295
uniprot id: A0A0S2JY79
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

161398:PP2015 RS04955
gene id: 161398:PP2015_RS04955
uniprot id: A0A0S2JZL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

161398:PP2015 RS06115
gene id: 161398:PP2015_RS06115
uniprot id: A0A0S2K0H1
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

161398:PP2015 RS12390
gene id: 161398:PP2015_RS12390
uniprot id: A0A0S2K3M7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

161398:PP2015 RS10330
gene id: 161398:PP2015_RS10330
uniprot id: A0A0S2K2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

161398:PP2015 RS01550
gene id: 161398:PP2015_RS01550
uniprot id: A0A0S2JY80
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

161398:PP2015 RS21345
gene id: 161398:PP2015_RS21345
uniprot id: A0A0S2K8L2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

161398:PP2015 RS13845
gene id: 161398:PP2015_RS13845
uniprot id: A0A0S2K4C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

161398:PP2015 RS20700
gene id: 161398:PP2015_RS20700
uniprot id: A0A0S2K925
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS20455
gene id: 161398:PP2015_RS20455
uniprot id: A0A0S2K8Y1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161398:PP2015 RS21215
gene id: 161398:PP2015_RS21215
uniprot id: A0A0S2K8E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

161398:PP2015 RS17635
gene id: 161398:PP2015_RS17635
uniprot id: A0A0S2K7G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS15855
gene id: 161398:PP2015_RS15855
uniprot id: A0A0S2K6B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

161398:PP2015 RS07845
gene id: 161398:PP2015_RS07845
uniprot id: A0A0S2K175
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

161398:PP2015 RS13465
gene id: 161398:PP2015_RS13465
uniprot id: A0A0S2K3S0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

161398:PP2015 RS05710
gene id: 161398:PP2015_RS05710
uniprot id: A0A0S2K0Q8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS11040
gene id: 161398:PP2015_RS11040
uniprot id: A0A0S2K2W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS02550
gene id: 161398:PP2015_RS02550
uniprot id: A0A0S2JY73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS14630
gene id: 161398:PP2015_RS14630
uniprot id: A0A0S2K4W4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

161398:PP2015 RS03635
gene id: 161398:PP2015_RS03635
uniprot id: A0A0S2JYJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS17275
gene id: 161398:PP2015_RS17275
uniprot id: A0A0S2K675
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS11275
gene id: 161398:PP2015_RS11275
uniprot id: A0A0S2K339
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS00120
gene id: 161398:PP2015_RS00120
uniprot id: A0A0S2JWS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

161398:PP2015 RS04670
gene id: 161398:PP2015_RS04670
uniprot id: A0A0S2K076
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

161398:PP2015 RS00020
gene id: 161398:PP2015_RS00020
uniprot id: A0A0S2JWX9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

161398:PP2015 RS15380
gene id: 161398:PP2015_RS15380
uniprot id: A0A0S2K641
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

161398:PP2015 RS05965
gene id: 161398:PP2015_RS05965
uniprot id: A0A0S2K0Y0
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS14565
gene id: 161398:PP2015_RS14565
uniprot id: A0A0S2K5L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS16880
gene id: 161398:PP2015_RS16880
uniprot id: A0A5R9PYJ2
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS13675
gene id: 161398:PP2015_RS13675
uniprot id: A0A0S2K3V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

161398:PP2015 RS02840
gene id: 161398:PP2015_RS02840
uniprot id: A0A0S2JZ02
names: Similarity
messages: Belongs to the peptidase S41A family.

161398:PP2015 RS08965
gene id: 161398:PP2015_RS08965
uniprot id: A0A0S2K1U1
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS06580
gene id: 161398:PP2015_RS06580
uniprot id: A0A0S2K173
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS07285
gene id: 161398:PP2015_RS07285
uniprot id: A0A0S2K0B2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

161398:PP2015 RS10530
gene id: 161398:PP2015_RS10530
uniprot id: A0A0S2K2Q4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS17675
gene id: 161398:PP2015_RS17675
uniprot id: A0A0S2K608
names: Similarity
messages: Belongs to the phosphohexose mutase family.

161398:PP2015 RS07745
gene id: 161398:PP2015_RS07745
uniprot id: A0A0S2K1X3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

161398:PP2015 RS05555
gene id: 161398:PP2015_RS05555
uniprot id: A0A0S2K0I8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

161398:PP2015 RS15830
gene id: 161398:PP2015_RS15830
uniprot id: A0A0S2K649
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

161398:PP2015 RS07705
gene id: 161398:PP2015_RS07705
uniprot id: A0A0S2K150
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS08735
gene id: 161398:PP2015_RS08735
uniprot id: A0A0S2K1N2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

161398:PP2015 RS21135
gene id: 161398:PP2015_RS21135
uniprot id: A0A0S2K8C5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

161398:PP2015 RS01010
gene id: 161398:PP2015_RS01010
uniprot id: A0A0S2JY63
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

161398:PP2015 RS16280
gene id: 161398:PP2015_RS16280
uniprot id: A0A0S2K6D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

161398:PP2015 RS16540
gene id: 161398:PP2015_RS16540
uniprot id: A0A0S2K650
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

161398:PP2015 RS07740
gene id: 161398:PP2015_RS07740
uniprot id: A0A0S2K234
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

161398:PP2015 RS15430
gene id: 161398:PP2015_RS15430
uniprot id: A0A0S2K5H6
names: Similarity
messages: Belongs to the arginase family.

161398:PP2015 RS00650
gene id: 161398:PP2015_RS00650
uniprot id: A0A0S2JX13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

161398:PP2015 RS10315
gene id: 161398:PP2015_RS10315
uniprot id: A0A0S2K213
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

161398:PP2015 RS13765
gene id: 161398:PP2015_RS13765
uniprot id: A0A0S2K4B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

161398:PP2015 RS10720
gene id: 161398:PP2015_RS10720
uniprot id: A0A0S2K2R5
names: Similarity
messages: Belongs to the peptidase S9C family.

161398:PP2015 RS13095
gene id: 161398:PP2015_RS13095
uniprot id: A0A0S2K4T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

161398:PP2015 RS14005
gene id: 161398:PP2015_RS14005
uniprot id: A0A0S2K4G3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS15335
gene id: 161398:PP2015_RS15335
uniprot id: A0A0S2K4R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS13085
gene id: 161398:PP2015_RS13085
uniprot id: A0A0S2K442
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS00480
gene id: 161398:PP2015_RS00480
uniprot id: A0A0S2JX71
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS12670
gene id: 161398:PP2015_RS12670
uniprot id: A0A0S2K4X2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

161398:PP2015 RS06950
gene id: 161398:PP2015_RS06950
uniprot id: A0A0S2K1D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

161398:PP2015 RS03055
gene id: 161398:PP2015_RS03055
uniprot id: A0A0S2JYK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

161398:PP2015 RS18510
gene id: 161398:PP2015_RS18510
uniprot id: A0A0S2K7T6
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

161398:PP2015 RS03735
gene id: 161398:PP2015_RS03735
uniprot id: A0A0S2JZG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS06960
gene id: 161398:PP2015_RS06960
uniprot id: A0A0S2K0P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

161398:PP2015 RS01565
gene id: 161398:PP2015_RS01565
uniprot id: A0A0S2JXF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

161398:PP2015 RS17845
gene id: 161398:PP2015_RS17845
uniprot id: A0A0S2K6H7
names: Similarity
messages: Belongs to the peptidase M4 family.

161398:PP2015 RS01750
gene id: 161398:PP2015_RS01750
uniprot id: A0A0S2JXV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS12325
gene id: 161398:PP2015_RS12325
uniprot id: A0A0S2K4D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

161398:PP2015 RS11685
gene id: 161398:PP2015_RS11685
uniprot id: A0A0S2K2U2
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

161398:PP2015 RS16090
gene id: 161398:PP2015_RS16090
uniprot id: A0A0S2K6M9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

161398:PP2015 RS07685
gene id: 161398:PP2015_RS07685
uniprot id: A0A0S2K0H7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

161398:PP2015 RS06790
gene id: 161398:PP2015_RS06790
uniprot id: A0A0S2K039
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS08870
gene id: 161398:PP2015_RS08870
uniprot id: A0A4Q7ITN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

161398:PP2015 RS13390
gene id: 161398:PP2015_RS13390
uniprot id: A0A0S2K457
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

161398:PP2015 RS14265
gene id: 161398:PP2015_RS14265
uniprot id: A0A0S2K481
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

161398:PP2015 RS04650
gene id: 161398:PP2015_RS04650
uniprot id: A0A0S2K038
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

161398:PP2015 RS07425
gene id: 161398:PP2015_RS07425
uniprot id: A0A0S2K1P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS20870
gene id: 161398:PP2015_RS20870
uniprot id: A0A0S2K955
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

161398:PP2015 RS05385
gene id: 161398:PP2015_RS05385
uniprot id: A0A0S2JZM8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS00220
gene id: 161398:PP2015_RS00220
uniprot id: A0A0S2JWZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

161398:PP2015 RS14985
gene id: 161398:PP2015_RS14985
uniprot id: A0A0S2K520
names: Similarity
messages: Belongs to the UPF0234 family.

161398:PP2015 RS02860
gene id: 161398:PP2015_RS02860
uniprot id: A0A0S2JYG6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

161398:PP2015 RS01855
gene id: 161398:PP2015_RS01855
uniprot id: A0A0S2JY26
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS03650
gene id: 161398:PP2015_RS03650
uniprot id: A0A0S2JZP1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

161398:PP2015 RS11715
gene id: 161398:PP2015_RS11715
uniprot id: A0A0S2K342
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

161398:PP2015 RS16185
gene id: 161398:PP2015_RS16185
uniprot id: A0A0S2K6F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

161398:PP2015 RS04595
gene id: 161398:PP2015_RS04595
uniprot id: A0A0S2JZT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

161398:PP2015 RS19490
gene id: 161398:PP2015_RS19490
uniprot id: A0A0S2K7V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

161398:PP2015 RS00135
gene id: 161398:PP2015_RS00135
uniprot id: A0A0S2JX39
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

161398:PP2015 RS02410
gene id: 161398:PP2015_RS02410
uniprot id: A0A0S2JYW1
names: Similarity
messages: Belongs to the cytochrome P450 family.

161398:PP2015 RS06875
gene id: 161398:PP2015_RS06875
uniprot id: A0A0S2K049
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

161398:PP2015 RS16755
gene id: 161398:PP2015_RS16755
uniprot id: A0A0S2K709
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

161398:PP2015 RS03815
gene id: 161398:PP2015_RS03815
uniprot id: A0A0S2JZH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

161398:PP2015 RS15375
gene id: 161398:PP2015_RS15375
uniprot id: A0A0S2K6A5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS15415
gene id: 161398:PP2015_RS15415
uniprot id: A0A0S2K4S6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS12450
gene id: 161398:PP2015_RS12450
uniprot id: A0A0S2K4A5
names: Similarity
messages: Belongs to the GSP E family.

161398:PP2015 RS07535
gene id: 161398:PP2015_RS07535
uniprot id: A0A0S2K1B6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

161398:PP2015 RS12525
gene id: 161398:PP2015_RS12525
uniprot id: A0A0S2K383
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

161398:PP2015 RS16120
gene id: 161398:PP2015_RS16120
uniprot id: A0A0S2K635
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS01970
gene id: 161398:PP2015_RS01970
uniprot id: A0A0S2JXY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

161398:PP2015 RS02740
gene id: 161398:PP2015_RS02740
uniprot id: A0A0S2JYI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

161398:PP2015 RS15400
gene id: 161398:PP2015_RS15400
uniprot id: A0A0S2K4S9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

161398:PP2015 RS09725
gene id: 161398:PP2015_RS09725
uniprot id: A0A0S2K1Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

161398:PP2015 RS19530
gene id: 161398:PP2015_RS19530
uniprot id: A0A0S2K7Q2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

161398:PP2015 RS00740
gene id: 161398:PP2015_RS00740
uniprot id: A0A0S2JX76
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

161398:PP2015 RS05440
gene id: 161398:PP2015_RS05440
uniprot id: A0A0S2JZY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

161398:PP2015 RS17280
gene id: 161398:PP2015_RS17280
uniprot id: A0A0S2K697
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

161398:PP2015 RS15440
gene id: 161398:PP2015_RS15440
uniprot id: A0A0S2K642
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

161398:PP2015 RS15215
gene id: 161398:PP2015_RS15215
uniprot id: A0A0S2K561
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

161398:PP2015 RS05285
gene id: 161398:PP2015_RS05285
uniprot id: A0A0S2JZT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

161398:PP2015 RS01890
gene id: 161398:PP2015_RS01890
uniprot id: A0A0S2JXW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

161398:PP2015 RS00500
gene id: 161398:PP2015_RS00500
uniprot id: A0A0S2JX23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

161398:PP2015 RS15425
gene id: 161398:PP2015_RS15425
uniprot id: A0A0S2K581
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

161398:PP2015 RS07990
gene id: 161398:PP2015_RS07990
uniprot id: A0A0S2K1Y6
names: Similarity
messages: Belongs to the sulfatase family.

161398:PP2015 RS04405
gene id: 161398:PP2015_RS04405
uniprot id: A0A0S2JYX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS10460
gene id: 161398:PP2015_RS10460
uniprot id: A0A0S2K365
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

161398:PP2015 RS14870
gene id: 161398:PP2015_RS14870
uniprot id: A0A0S2K4I0
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

161398:PP2015 RS11975
gene id: 161398:PP2015_RS11975
uniprot id: A0A0S2K3Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

161398:PP2015 RS10000
gene id: 161398:PP2015_RS10000
uniprot id: A0A0S2K2X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

161398:PP2015 RS05970
gene id: 161398:PP2015_RS05970
uniprot id: A0A0S2K0R1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

161398:PP2015 RS11720
gene id: 161398:PP2015_RS11720
uniprot id: A0A0S2K3F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

161398:PP2015 RS08075
gene id: 161398:PP2015_RS08075
uniprot id: A0A0S2K205
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

161398:PP2015 RS13615
gene id: 161398:PP2015_RS13615
uniprot id: A0A0S2K4G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

161398:PP2015 RS03010
gene id: 161398:PP2015_RS03010
uniprot id: A0A0S2JYZ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

161398:PP2015 RS15150
gene id: 161398:PP2015_RS15150
uniprot id: A0A0S2K5X1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

161398:PP2015 RS08840
gene id: 161398:PP2015_RS08840
uniprot id: A0A0S2K2T2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

161398:PP2015 RS08275
gene id: 161398:PP2015_RS08275
uniprot id: A0A0S2K1E6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

161398:PP2015 RS20990
gene id: 161398:PP2015_RS20990
uniprot id: A0A0S2K8B5
names: Cofactor
names: Subunit
messages: Binds 1 zinc ion.
messages: Homodimer.

161398:PP2015 RS06030
gene id: 161398:PP2015_RS06030
uniprot id: A0A0S2K014
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

161398:PP2015 RS20720
gene id: 161398:PP2015_RS20720
uniprot id: A0A0S2K8H1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS06955
gene id: 161398:PP2015_RS06955
uniprot id: A0A0S2K1C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

161398:PP2015 RS11665
gene id: 161398:PP2015_RS11665
uniprot id: A0A0S2K3E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

161398:PP2015 RS09240
gene id: 161398:PP2015_RS09240
uniprot id: A0A0S2K1X5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

161398:PP2015 RS12520
gene id: 161398:PP2015_RS12520
uniprot id: A0A0S2K3V4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

161398:PP2015 RS09960
gene id: 161398:PP2015_RS09960
uniprot id: A0A0S2K231
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

161398:PP2015 RS10865
gene id: 161398:PP2015_RS10865
uniprot id: A0A0S2K349
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS00215
gene id: 161398:PP2015_RS00215
uniprot id: A0A0S2JWU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS07860
gene id: 161398:PP2015_RS07860
uniprot id: A0A0S2K1G5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

161398:PP2015 RS09005
gene id: 161398:PP2015_RS09005
uniprot id: A0A0S2K2W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.

161398:PP2015 RS16215
gene id: 161398:PP2015_RS16215
uniprot id: A0A0S2K570
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

161398:PP2015 RS12725
gene id: 161398:PP2015_RS12725
uniprot id: A0A0S2K432
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

161398:PP2015 RS18600
gene id: 161398:PP2015_RS18600
uniprot id: A0A0S2K7J8
names: Subcellular Location Annotation
messages: Secreted

161398:PP2015 RS07400
gene id: 161398:PP2015_RS07400
uniprot id: A0A0S2K1M6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS00125
gene id: 161398:PP2015_RS00125
uniprot id: A0A0S2JWY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

161398:PP2015 RS14225
gene id: 161398:PP2015_RS14225
uniprot id: A0A0S2K5F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

161398:PP2015 RS17235
gene id: 161398:PP2015_RS17235
uniprot id: A0A0S2K727
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

161398:PP2015 RS18055
gene id: 161398:PP2015_RS18055
uniprot id: A0A0S2K744
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

161398:PP2015 RS02930
gene id: 161398:PP2015_RS02930
uniprot id: A0A0S2JYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS02495
gene id: 161398:PP2015_RS02495
uniprot id: A0A0S2JXY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

161398:PP2015 RS06700
gene id: 161398:PP2015_RS06700
uniprot id: A0A0S2K024
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

161398:PP2015 RS04645
gene id: 161398:PP2015_RS04645
uniprot id: A0A0S2K074
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

161398:PP2015 RS09395
gene id: 161398:PP2015_RS09395
uniprot id: A0A0S2K1J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

161398:PP2015 RS14715
gene id: 161398:PP2015_RS14715
uniprot id: A0A0S2K600
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

161398:PP2015 RS10465
gene id: 161398:PP2015_RS10465
uniprot id: A0A0S2K2X2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

161398:PP2015 RS06530
gene id: 161398:PP2015_RS06530
uniprot id: A0A0S2K158
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS04820
gene id: 161398:PP2015_RS04820
uniprot id: A0A0S2JZM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

161398:PP2015 RS13990
gene id: 161398:PP2015_RS13990
uniprot id: A0A0S2K4S2
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS04485
gene id: 161398:PP2015_RS04485
uniprot id: A0A0S2K019
names: Similarity
messages: Belongs to the transglycosylase Slt family.

161398:PP2015 RS13935
gene id: 161398:PP2015_RS13935
uniprot id: A0A0S2K555
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

161398:PP2015 RS05405
gene id: 161398:PP2015_RS05405
uniprot id: A0A0S2K084
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS03990
gene id: 161398:PP2015_RS03990
uniprot id: A0A0S2JYV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

161398:PP2015 RS13580
gene id: 161398:PP2015_RS13580
uniprot id: A0A0S2K4C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS16925
gene id: 161398:PP2015_RS16925
uniprot id: A0A0S2K6W3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

161398:PP2015 RS15910
gene id: 161398:PP2015_RS15910
uniprot id: A0A0S2K665
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

161398:PP2015 RS14360
gene id: 161398:PP2015_RS14360
uniprot id: A0A0S2K4N6
names: Similarity
messages: Belongs to the histone deacetylase family.

161398:PP2015 RS08865
gene id: 161398:PP2015_RS08865
uniprot id: A0A0S2K164
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

161398:PP2015 RS21540
gene id: 161398:PP2015_RS21540
uniprot id: A0A0S2K8K1
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

161398:PP2015 RS04655
gene id: 161398:PP2015_RS04655
uniprot id: A0A0S2JZ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

161398:PP2015 RS03285
gene id: 161398:PP2015_RS03285
uniprot id: A0A0S2JYL8
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS10945
gene id: 161398:PP2015_RS10945
uniprot id: A0A0S2K368
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS02995
gene id: 161398:PP2015_RS02995
uniprot id: A0A0S2JYN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

161398:PP2015 RS09390
gene id: 161398:PP2015_RS09390
uniprot id: A0A0S2K2D2
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

161398:PP2015 RS06430
gene id: 161398:PP2015_RS06430
uniprot id: A0A0S2K0E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

161398:PP2015 RS09325
gene id: 161398:PP2015_RS09325
uniprot id: A0A0S2K1Z1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

161398:PP2015 RS21335
gene id: 161398:PP2015_RS21335
uniprot id: A0A0S2K9J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

161398:PP2015 RS08740
gene id: 161398:PP2015_RS08740
uniprot id: A0A0S2K1V0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

161398:PP2015 RS07795
gene id: 161398:PP2015_RS07795
uniprot id: A0A0S2K189
names: Similarity
messages: Belongs to the DEAD box helicase family.

161398:PP2015 RS00850
gene id: 161398:PP2015_RS00850
uniprot id: A0A0S2JX37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

161398:PP2015 RS11895
gene id: 161398:PP2015_RS11895
uniprot id: A0A0S2K3P2
names: Subcellular Location Annotation
messages: Membrane

161398:PP2015 RS05455
gene id: 161398:PP2015_RS05455
uniprot id: A0A0S2K0K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

161398:PP2015 RS14010
gene id: 161398:PP2015_RS14010
uniprot id: A0A0S2K4R1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

161398:PP2015 RS09730
gene id: 161398:PP2015_RS09730
uniprot id: A0A0S2K2C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

161398:PP2015 RS00735
gene id: 161398:PP2015_RS00735
uniprot id: A0A0S2JX83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

161398:PP2015 RS08730
gene id: 161398:PP2015_RS08730
uniprot id: A0A0S2K1P4
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

161398:PP2015 RS20375
gene id: 161398:PP2015_RS20375
uniprot id: A0A0S2K827
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

161398:PP2015 RS18775
gene id: 161398:PP2015_RS18775
uniprot id: A0A0S2K7F1
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

161398:PP2015 RS11905
gene id: 161398:PP2015_RS11905
uniprot id: A0A0S2K3E9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

161398:PP2015 RS06870
gene id: 161398:PP2015_RS06870
uniprot id: A0A0S2K0M6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

161398:PP2015 RS01340
gene id: 161398:PP2015_RS01340
uniprot id: A0A0S2JXH8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

161398:PP2015 RS11315
gene id: 161398:PP2015_RS11315
uniprot id: A0A0S2K3U6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

161398:PP2015 RS13525
gene id: 161398:PP2015_RS13525
uniprot id: A0A0S2K473
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

161398:PP2015 RS14875
gene id: 161398:PP2015_RS14875
uniprot id: A0A0S2K4Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

161398:PP2015 RS16200
gene id: 161398:PP2015_RS16200
uniprot id: A0A0S2K565
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

161398:PP2015 RS16165
gene id: 161398:PP2015_RS16165
uniprot id: A0A0S2K5F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

161398:PP2015 RS15695
gene id: 161398:PP2015_RS15695
uniprot id: A0A0S2K5M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

161398:PP2015 RS03660
gene id: 161398:PP2015_RS03660
uniprot id: A0A0S2JZM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

161398:PP2015 RS12435
gene id: 161398:PP2015_RS12435
uniprot id: A0A0S2K4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

161398:PP2015 RS14960
gene id: 161398:PP2015_RS14960
uniprot id: A0A0S2K4Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

161398:PP2015 RS13785
gene id: 161398:PP2015_RS13785
uniprot id: A0A0S2K469
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

161398:PP2015 RS05180
gene id: 161398:PP2015_RS05180
uniprot id: A0A0S2K002
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

161398:PP2015 RS01865
gene id: 161398:PP2015_RS01865
uniprot id: A0A0S2JYL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS04035
gene id: 161398:PP2015_RS04035
uniprot id: A0A0S2JZ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

161398:PP2015 RS07570
gene id: 161398:PP2015_RS07570
uniprot id: A0A0S2K0T0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

161398:PP2015 RS03605
gene id: 161398:PP2015_RS03605
uniprot id: A0A0S2JYK3
names: Similarity
messages: Belongs to the aldose epimerase family.

161398:PP2015 RS04420
gene id: 161398:PP2015_RS04420
uniprot id: A0A0S2JYZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

161398:PP2015 RS12185
gene id: 161398:PP2015_RS12185
uniprot id: A0A0S2K4B4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

161398:PP2015 RS09770
gene id: 161398:PP2015_RS09770
uniprot id: A0A0S2K1P7
names: Similarity
messages: Belongs to the UPF0229 family.

161398:PP2015 RS11185
gene id: 161398:PP2015_RS11185
uniprot id: A0A0S2K3C2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

161398:PP2015 RS03035
gene id: 161398:PP2015_RS03035
uniprot id: A0A0S2JYJ7
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

161398:PP2015 RS14200
gene id: 161398:PP2015_RS14200
uniprot id: A0A0S2K5B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

161398:PP2015 RS17325
gene id: 161398:PP2015_RS17325
uniprot id: A0A0S2K6V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

161398:PP2015 RS12270
gene id: 161398:PP2015_RS12270
uniprot id: A0A0S2K4C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

161398:PP2015 RS08860
gene id: 161398:PP2015_RS08860
uniprot id: A0A0S2K1T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

161398:PP2015 RS21330
gene id: 161398:PP2015_RS21330
uniprot id: A0A0S2K967
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

161398:PP2015 RS08370
gene id: 161398:PP2015_RS08370
uniprot id: A0A0S2K1N5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

161398:PP2015 RS17505
gene id: 161398:PP2015_RS17505
uniprot id: A0A0S2K6S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

161398:PP2015 RS10005
gene id: 161398:PP2015_RS10005
uniprot id: A0A0S2K2N3
names: Similarity
messages: Belongs to the fabD family.

161398:PP2015 RS10430
gene id: 161398:PP2015_RS10430
uniprot id: A0A0S2K2R6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

161398:PP2015 RS21280
gene id: 161398:PP2015_RS21280
uniprot id: A0A0S2K9C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

161398:PP2015 RS13530
gene id: 161398:PP2015_RS13530
uniprot id: A0A0S2K467
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

161398:PP2015 RS01185
gene id: 161398:PP2015_RS01185
uniprot id: A0A0S2JY94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

161398:PP2015 RS02815
gene id: 161398:PP2015_RS02815
uniprot id: A0A0S2JY46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

161398:PP2015 RS01040
gene id: 161398:PP2015_RS01040
uniprot id: A0A0S2JY34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

161398:PP2015 RS00730
gene id: 161398:PP2015_RS00730
uniprot id: A0A0S2JX28
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.