158847:CKV65 RS03505
gene id: 158847:CKV65_RS03505
uniprot id: A0A239TIB4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

158847:CKV65 RS09640
gene id: 158847:CKV65_RS09640
uniprot id: A0A239U2I3
names: Similarity
messages: Belongs to the ThiD family.

158847:CKV65 RS09185
gene id: 158847:CKV65_RS09185
uniprot id: A0A239U1V8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

158847:CKV65 RS05630
gene id: 158847:CKV65_RS05630
uniprot id: A0A239TQ12
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

158847:CKV65 RS08180
gene id: 158847:CKV65_RS08180
uniprot id: A0A239TYQ7
names: Similarity
messages: Belongs to the aldose epimerase family.

158847:CKV65 RS03800
gene id: 158847:CKV65_RS03800
uniprot id: A0A239TI81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

158847:CKV65 RS06095
gene id: 158847:CKV65_RS06095
uniprot id: A0A239TSE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

158847:CKV65 RS00465
gene id: 158847:CKV65_RS00465
uniprot id: A0A239T8N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

158847:CKV65 RS08580
gene id: 158847:CKV65_RS08580
uniprot id: A0A239U120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

158847:CKV65 RS05425
gene id: 158847:CKV65_RS05425
uniprot id: A0A239TNF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

158847:CKV65 RS02480
gene id: 158847:CKV65_RS02480
uniprot id: A0A239TEF4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

158847:CKV65 RS05950
gene id: 158847:CKV65_RS05950
uniprot id: A0A239TQX5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

158847:CKV65 RS05060
gene id: 158847:CKV65_RS05060
uniprot id: A0A239TN99
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

158847:CKV65 RS04010
gene id: 158847:CKV65_RS04010
uniprot id: A0A239TK18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

158847:CKV65 RS08395
gene id: 158847:CKV65_RS08395
uniprot id: A0A239TZ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

158847:CKV65 RS01690
gene id: 158847:CKV65_RS01690
uniprot id: A0A239TBV6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

158847:CKV65 RS00105
gene id: 158847:CKV65_RS00105
uniprot id: A0A239T7Q7
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

158847:CKV65 RS09130
gene id: 158847:CKV65_RS09130
uniprot id: A0A239U2Z4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

158847:CKV65 RS03555
gene id: 158847:CKV65_RS03555
uniprot id: A0A239THU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS08780
gene id: 158847:CKV65_RS08780
uniprot id: A0A239U012
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

158847:CKV65 RS05455
gene id: 158847:CKV65_RS05455
uniprot id: A0A239TNQ0
names: Similarity
messages: Belongs to the CinA family.

158847:CKV65 RS04130
gene id: 158847:CKV65_RS04130
uniprot id: A0A239TL48
names: Similarity
messages: Belongs to the PRORSD1 family.

158847:CKV65 RS00115
gene id: 158847:CKV65_RS00115
uniprot id: A0A239T8Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

158847:CKV65 RS06465
gene id: 158847:CKV65_RS06465
uniprot id: A0A239TSJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

158847:CKV65 RS03675
gene id: 158847:CKV65_RS03675
uniprot id: A0A239TJM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS00640
gene id: 158847:CKV65_RS00640
uniprot id: A0A239TAY2
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS01195
gene id: 158847:CKV65_RS01195
uniprot id: A0A239TAS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

158847:CKV65 RS04190
gene id: 158847:CKV65_RS04190
uniprot id: A0A239TN34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS00990
gene id: 158847:CKV65_RS00990
uniprot id: A0A239T9E5
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

158847:CKV65 RS04310
gene id: 158847:CKV65_RS04310
uniprot id: A0A239TKQ0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

158847:CKV65 RS00175
gene id: 158847:CKV65_RS00175
uniprot id: A0A239T7Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

158847:CKV65 RS10615
gene id: 158847:CKV65_RS10615
uniprot id: A0A239U650
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

158847:CKV65 RS08600
gene id: 158847:CKV65_RS08600
uniprot id: A0A239U084
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

158847:CKV65 RS03930
gene id: 158847:CKV65_RS03930
uniprot id: A0A239TJT6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS03125
gene id: 158847:CKV65_RS03125
uniprot id: A0A239TGW7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

158847:CKV65 RS06035
gene id: 158847:CKV65_RS06035
uniprot id: A0A239TQF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

158847:CKV65 RS04045
gene id: 158847:CKV65_RS04045
uniprot id: A0A239TJW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

158847:CKV65 RS01990
gene id: 158847:CKV65_RS01990
uniprot id: A0A239TD40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

158847:CKV65 RS05745
gene id: 158847:CKV65_RS05745
uniprot id: A0A239TPB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

158847:CKV65 RS09500
gene id: 158847:CKV65_RS09500
uniprot id: A0A239U2S4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS07240
gene id: 158847:CKV65_RS07240
uniprot id: A0A239TXU8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

158847:CKV65 RS08865
gene id: 158847:CKV65_RS08865
uniprot id: A0A239U2B3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS10895
gene id: 158847:CKV65_RS10895
uniprot id: A0A239TFB4
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

158847:CKV65 RS03500
gene id: 158847:CKV65_RS03500
uniprot id: A0A239TK23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

158847:CKV65 RS06295
gene id: 158847:CKV65_RS06295
uniprot id: A0A239TS07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS07120
gene id: 158847:CKV65_RS07120
uniprot id: A0A239TUR3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS07235
gene id: 158847:CKV65_RS07235
uniprot id: A0A239TV80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

158847:CKV65 RS06440
gene id: 158847:CKV65_RS06440
uniprot id: A0A239TSG8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

158847:CKV65 RS00915
gene id: 158847:CKV65_RS00915
uniprot id: A0A239T9L5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

158847:CKV65 RS09815
gene id: 158847:CKV65_RS09815
uniprot id: A0A239U6F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

158847:CKV65 RS04255
gene id: 158847:CKV65_RS04255
uniprot id: A0A239TK00
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS08655
gene id: 158847:CKV65_RS08655
uniprot id: A0A239U0D5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

158847:CKV65 RS07245
gene id: 158847:CKV65_RS07245
uniprot id: A0A239TV88
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

158847:CKV65 RS03755
gene id: 158847:CKV65_RS03755
uniprot id: A0A239TL02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

158847:CKV65 RS04455
gene id: 158847:CKV65_RS04455
uniprot id: A0A239TKT3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS03310
gene id: 158847:CKV65_RS03310
uniprot id: A0A239TJZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

158847:CKV65 RS08835
gene id: 158847:CKV65_RS08835
uniprot id: A0A239U0R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS00395
gene id: 158847:CKV65_RS00395
uniprot id: A0A239T7S4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

158847:CKV65 RS07975
gene id: 158847:CKV65_RS07975
uniprot id: A0A239U0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

158847:CKV65 RS02850
gene id: 158847:CKV65_RS02850
uniprot id: A0A239TFC9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

158847:CKV65 RS00475
gene id: 158847:CKV65_RS00475
uniprot id: A0A239T7Y9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

158847:CKV65 RS08035
gene id: 158847:CKV65_RS08035
uniprot id: A0A239TZL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS07205
gene id: 158847:CKV65_RS07205
uniprot id: A0A239TVJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

158847:CKV65 RS08080
gene id: 158847:CKV65_RS08080
uniprot id: A0A239TY68
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

158847:CKV65 RS06200
gene id: 158847:CKV65_RS06200
uniprot id: A0A239TR13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

158847:CKV65 RS05205
gene id: 158847:CKV65_RS05205
uniprot id: A0A239TN86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

158847:CKV65 RS07275
gene id: 158847:CKV65_RS07275
uniprot id: A0A239TW37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

158847:CKV65 RS00955
gene id: 158847:CKV65_RS00955
uniprot id: A0A239T9A6
names: Similarity
messages: Belongs to the Skp family.

158847:CKV65 RS02260
gene id: 158847:CKV65_RS02260
uniprot id: A0A239TDP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

158847:CKV65 RS06015
gene id: 158847:CKV65_RS06015
uniprot id: A0A239TRE1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

158847:CKV65 RS03275
gene id: 158847:CKV65_RS03275
uniprot id: A0A239THJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

158847:CKV65 RS07380
gene id: 158847:CKV65_RS07380
uniprot id: A0A239TVU3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

158847:CKV65 RS05460
gene id: 158847:CKV65_RS05460
uniprot id: A0A239TPH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

158847:CKV65 RS09035
gene id: 158847:CKV65_RS09035
uniprot id: A0A239U3Q4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

158847:CKV65 RS08575
gene id: 158847:CKV65_RS08575
uniprot id: A0A239U0G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

158847:CKV65 RS04950
gene id: 158847:CKV65_RS04950
uniprot id: A0A239TMX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

158847:CKV65 RS01675
gene id: 158847:CKV65_RS01675
uniprot id: A0A239TBS4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

158847:CKV65 RS07685
gene id: 158847:CKV65_RS07685
uniprot id: A0A239TZJ5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

158847:CKV65 RS02595
gene id: 158847:CKV65_RS02595
uniprot id: A0A239TEI0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

158847:CKV65 RS09730
gene id: 158847:CKV65_RS09730
uniprot id: A0A239U2V8
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

158847:CKV65 RS06040
gene id: 158847:CKV65_RS06040
uniprot id: A0A239TR30
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

158847:CKV65 RS01740
gene id: 158847:CKV65_RS01740
uniprot id: A0A239TDK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

158847:CKV65 RS08530
gene id: 158847:CKV65_RS08530
uniprot id: A0A239U2I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

158847:CKV65 RS06380
gene id: 158847:CKV65_RS06380
uniprot id: A0A239TTD4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

158847:CKV65 RS09355
gene id: 158847:CKV65_RS09355
uniprot id: A0A239U4I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

158847:CKV65 RS02355
gene id: 158847:CKV65_RS02355
uniprot id: A0A239TDK9
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3'.
messages: Belongs to the DpnII type II restriction endonuclease family.

158847:CKV65 RS02735
gene id: 158847:CKV65_RS02735
uniprot id: A0A239TFE9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

158847:CKV65 RS10155
gene id: 158847:CKV65_RS10155
uniprot id: A0A239U6C0
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

158847:CKV65 RS05960
gene id: 158847:CKV65_RS05960
uniprot id: A0A239TQY1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

158847:CKV65 RS02705
gene id: 158847:CKV65_RS02705
uniprot id: A0A239TEY9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

158847:CKV65 RS00660
gene id: 158847:CKV65_RS00660
uniprot id: A0A239TAF2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

158847:CKV65 RS03240
gene id: 158847:CKV65_RS03240
uniprot id: A0A239TJ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS05725
gene id: 158847:CKV65_RS05725
uniprot id: A0A239TT02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

158847:CKV65 RS01575
gene id: 158847:CKV65_RS01575
uniprot id: A0A239TC69
names: Subcellular Location Annotation
messages: Cell membrane

158847:CKV65 RS02415
gene id: 158847:CKV65_RS02415
uniprot id: A0A239TE96
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

158847:CKV65 RS01310
gene id: 158847:CKV65_RS01310
uniprot id: A0A239TAV2
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS06175
gene id: 158847:CKV65_RS06175
uniprot id: A0A239TSQ6
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS02125
gene id: 158847:CKV65_RS02125
uniprot id: A0A239TF75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

158847:CKV65 RS04415
gene id: 158847:CKV65_RS04415
uniprot id: A0A239TKF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

158847:CKV65 RS09495
gene id: 158847:CKV65_RS09495
uniprot id: A0A239U3E4
names: Similarity
messages: Belongs to the transpeptidase family.

158847:CKV65 RS00505
gene id: 158847:CKV65_RS00505
uniprot id: A0A239T809
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

158847:CKV65 RS04635
gene id: 158847:CKV65_RS04635
uniprot id: A0A239TLR9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

158847:CKV65 RS04050
gene id: 158847:CKV65_RS04050
uniprot id: A0A239TJD6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

158847:CKV65 RS02855
gene id: 158847:CKV65_RS02855
uniprot id: A0A239TFK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

158847:CKV65 RS03530
gene id: 158847:CKV65_RS03530
uniprot id: A0A239THG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

158847:CKV65 RS01120
gene id: 158847:CKV65_RS01120
uniprot id: A0A239TA14
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

158847:CKV65 RS06755
gene id: 158847:CKV65_RS06755
uniprot id: A0A239TTF6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

158847:CKV65 RS07815
gene id: 158847:CKV65_RS07815
uniprot id: A0A239TX75
names: Subcellular Location Annotation
messages: Cytoplasm

158847:CKV65 RS07450
gene id: 158847:CKV65_RS07450
uniprot id: A0A239TW33
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

158847:CKV65 RS10470
gene id: 158847:CKV65_RS10470
uniprot id: A0A239U5V6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

158847:CKV65 RS06180
gene id: 158847:CKV65_RS06180
uniprot id: A0A239TQU4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

158847:CKV65 RS05230
gene id: 158847:CKV65_RS05230
uniprot id: A0A239TNW8
names: Similarity
messages: Belongs to the RecJ family.

158847:CKV65 RS02270
gene id: 158847:CKV65_RS02270
uniprot id: A0A239TDD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

158847:CKV65 RS04085
gene id: 158847:CKV65_RS04085
uniprot id: A0A239TJ55
names: Similarity
messages: Belongs to the EamA transporter family.

158847:CKV65 RS05380
gene id: 158847:CKV65_RS05380
uniprot id: A0A239TNT4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

158847:CKV65 RS06185
gene id: 158847:CKV65_RS06185
uniprot id: A0A239TR56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

158847:CKV65 RS10455
gene id: 158847:CKV65_RS10455
uniprot id: A0A239U5L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

158847:CKV65 RS02055
gene id: 158847:CKV65_RS02055
uniprot id: A0A239TF70
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

158847:CKV65 RS02090
gene id: 158847:CKV65_RS02090
uniprot id: A0A239TDA3
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS01015
gene id: 158847:CKV65_RS01015
uniprot id: A0A239TA16
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

158847:CKV65 RS09090
gene id: 158847:CKV65_RS09090
uniprot id: A0A239U2W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

158847:CKV65 RS09560
gene id: 158847:CKV65_RS09560
uniprot id: A0A239U300
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

158847:CKV65 RS07390
gene id: 158847:CKV65_RS07390
uniprot id: A0A239TYI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

158847:CKV65 RS05400
gene id: 158847:CKV65_RS05400
uniprot id: A0A239TNV5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

158847:CKV65 RS05490
gene id: 158847:CKV65_RS05490
uniprot id: A0A239TP43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

158847:CKV65 RS03850
gene id: 158847:CKV65_RS03850
uniprot id: A0A239TLX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

158847:CKV65 RS03450
gene id: 158847:CKV65_RS03450
uniprot id: A0A239TI25
names: Similarity
messages: Belongs to the TelA family.

158847:CKV65 RS02520
gene id: 158847:CKV65_RS02520
uniprot id: A0A239TED4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS01815
gene id: 158847:CKV65_RS01815
uniprot id: A0A239TCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

158847:CKV65 RS09955
gene id: 158847:CKV65_RS09955
uniprot id: A0A239U4G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

158847:CKV65 RS00120
gene id: 158847:CKV65_RS00120
uniprot id: A0A239T903
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

158847:CKV65 RS07785
gene id: 158847:CKV65_RS07785
uniprot id: A0A239TX67
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

158847:CKV65 RS07110
gene id: 158847:CKV65_RS07110
uniprot id: A0A239TXS9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

158847:CKV65 RS01265
gene id: 158847:CKV65_RS01265
uniprot id: A0A239TB69
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS07025
gene id: 158847:CKV65_RS07025
uniprot id: A0A239TWD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

158847:CKV65 RS02120
gene id: 158847:CKV65_RS02120
uniprot id: A0A239TCW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

158847:CKV65 RS04275
gene id: 158847:CKV65_RS04275
uniprot id: A0A239TNB4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

158847:CKV65 RS00970
gene id: 158847:CKV65_RS00970
uniprot id: A0A239TBK1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

158847:CKV65 RS06385
gene id: 158847:CKV65_RS06385
uniprot id: A0A239TU71
names: Similarity
messages: Belongs to the ThiD family.

158847:CKV65 RS05305
gene id: 158847:CKV65_RS05305
uniprot id: A0A239TNJ2
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS07020
gene id: 158847:CKV65_RS07020
uniprot id: A0A239TUG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

158847:CKV65 RS00515
gene id: 158847:CKV65_RS00515
uniprot id: A0A239T8T0
names: Similarity
messages: Belongs to the EamA transporter family.

158847:CKV65 RS03575
gene id: 158847:CKV65_RS03575
uniprot id: A0A239TL19
names: Similarity
messages: Belongs to the UPF0173 family.

158847:CKV65 RS05335
gene id: 158847:CKV65_RS05335
uniprot id: A0A239TPH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

158847:CKV65 RS04260
gene id: 158847:CKV65_RS04260
uniprot id: A0A239TK10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

158847:CKV65 RS03095
gene id: 158847:CKV65_RS03095
uniprot id: A0A239TGL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

158847:CKV65 RS00155
gene id: 158847:CKV65_RS00155
uniprot id: A0A239T9F6
names: Similarity
messages: Belongs to the EamA transporter family.

158847:CKV65 RS02420
gene id: 158847:CKV65_RS02420
uniprot id: A0A239TDW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

158847:CKV65 RS05880
gene id: 158847:CKV65_RS05880
uniprot id: A0A239TRX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

158847:CKV65 RS03490
gene id: 158847:CKV65_RS03490
uniprot id: A0A239TKN2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

158847:CKV65 RS05540
gene id: 158847:CKV65_RS05540
uniprot id: A0A239TPP8
names: Similarity
messages: Belongs to the Lgt family.

158847:CKV65 RS07250
gene id: 158847:CKV65_RS07250
uniprot id: A0A239TX31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

158847:CKV65 RS03580
gene id: 158847:CKV65_RS03580
uniprot id: A0A239THY3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158847:CKV65 RS00930
gene id: 158847:CKV65_RS00930
uniprot id: A0A239T9T9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

158847:CKV65 RS04790
gene id: 158847:CKV65_RS04790
uniprot id: A0A239TLY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS03690
gene id: 158847:CKV65_RS03690
uniprot id: A0A239TIG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

158847:CKV65 RS03120
gene id: 158847:CKV65_RS03120
uniprot id: A0A239TGQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

158847:CKV65 RS08385
gene id: 158847:CKV65_RS08385
uniprot id: A0A239TZD3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

158847:CKV65 RS04245
gene id: 158847:CKV65_RS04245
uniprot id: A0A239TJZ2
names: Similarity
messages: Belongs to the GARS family.

158847:CKV65 RS02205
gene id: 158847:CKV65_RS02205
uniprot id: A0A239TDG2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

158847:CKV65 RS07715
gene id: 158847:CKV65_RS07715
uniprot id: A0A239TXI9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

158847:CKV65 RS02775
gene id: 158847:CKV65_RS02775
uniprot id: A0A239TF45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

158847:CKV65 RS04610
gene id: 158847:CKV65_RS04610
uniprot id: A0A239TL18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

158847:CKV65 RS03890
gene id: 158847:CKV65_RS03890
uniprot id: A0A239TJD3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

158847:CKV65 RS04650
gene id: 158847:CKV65_RS04650
uniprot id: A0A239TPM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

158847:CKV65 RS01645
gene id: 158847:CKV65_RS01645
uniprot id: A0A239TBQ1
names: Similarity
messages: Belongs to the universal stress protein A family.

158847:CKV65 RS07100
gene id: 158847:CKV65_RS07100
uniprot id: A0A239TX65
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

158847:CKV65 RS00885
gene id: 158847:CKV65_RS00885
uniprot id: A0A239T936
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

158847:CKV65 RS02940
gene id: 158847:CKV65_RS02940
uniprot id: A0A239TFQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

158847:CKV65 RS09300
gene id: 158847:CKV65_RS09300
uniprot id: A0A239U4Q9
names: Similarity
messages: Belongs to the peptidase M29 family.

158847:CKV65 RS09595
gene id: 158847:CKV65_RS09595
uniprot id: A0A239U4D2
names: Similarity
messages: Belongs to the ParB family.

158847:CKV65 RS07140
gene id: 158847:CKV65_RS07140
uniprot id: A0A239TVK7
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

158847:CKV65 RS03285
gene id: 158847:CKV65_RS03285
uniprot id: A0A239TGY7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

158847:CKV65 RS06685
gene id: 158847:CKV65_RS06685
uniprot id: A0A239TUM2
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS02870
gene id: 158847:CKV65_RS02870
uniprot id: A0A239TFH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

158847:CKV65 RS10180
gene id: 158847:CKV65_RS10180
uniprot id: A0A239U551
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

158847:CKV65 RS00875
gene id: 158847:CKV65_RS00875
uniprot id: A0A239TAY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

158847:CKV65 RS02075
gene id: 158847:CKV65_RS02075
uniprot id: A0A239TD55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

158847:CKV65 RS10175
gene id: 158847:CKV65_RS10175
uniprot id: A0A239U4D9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS03215
gene id: 158847:CKV65_RS03215
uniprot id: A0A239TH86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

158847:CKV65 RS04955
gene id: 158847:CKV65_RS04955
uniprot id: A0A239TNZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

158847:CKV65 RS03775
gene id: 158847:CKV65_RS03775
uniprot id: A0A239TIH7
names: Similarity
messages: Belongs to the UPF0473 family.

158847:CKV65 RS06105
gene id: 158847:CKV65_RS06105
uniprot id: A0A239TSF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

158847:CKV65 RS02975
gene id: 158847:CKV65_RS02975
uniprot id: A0A239TH05
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

158847:CKV65 RS04655
gene id: 158847:CKV65_RS04655
uniprot id: A0A239TL22
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS00590
gene id: 158847:CKV65_RS00590
uniprot id: A0A239T873
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

158847:CKV65 RS04425
gene id: 158847:CKV65_RS04425
uniprot id: A0A239TL32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

158847:CKV65 RS03550
gene id: 158847:CKV65_RS03550
uniprot id: A0A239TI09
names: Similarity
messages: Belongs to the TlyA family.

158847:CKV65 RS05085
gene id: 158847:CKV65_RS05085
uniprot id: A0A239TNF9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

158847:CKV65 RS06350
gene id: 158847:CKV65_RS06350
uniprot id: A0A239TRC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

158847:CKV65 RS01635
gene id: 158847:CKV65_RS01635
uniprot id: A0A239TCA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

158847:CKV65 RS09950
gene id: 158847:CKV65_RS09950
uniprot id: A0A239U454
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS08945
gene id: 158847:CKV65_RS08945
uniprot id: A0A239U0V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

158847:CKV65 RS06250
gene id: 158847:CKV65_RS06250
uniprot id: A0A239TRY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

158847:CKV65 RS04515
gene id: 158847:CKV65_RS04515
uniprot id: A0A239TLS5
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

158847:CKV65 RS09450
gene id: 158847:CKV65_RS09450
uniprot id: A0A239U3W1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS06665
gene id: 158847:CKV65_RS06665
uniprot id: A0A239TTH2
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

158847:CKV65 RS01385
gene id: 158847:CKV65_RS01385
uniprot id: A0A239TB85
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS00190
gene id: 158847:CKV65_RS00190
uniprot id: A0A239T7A8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

158847:CKV65 RS06615
gene id: 158847:CKV65_RS06615
uniprot id: A0A239TUB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

158847:CKV65 RS02840
gene id: 158847:CKV65_RS02840
uniprot id: A0A239TFS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

158847:CKV65 RS02800
gene id: 158847:CKV65_RS02800
uniprot id: A0A239THZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS03025
gene id: 158847:CKV65_RS03025
uniprot id: A0A239TG30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

158847:CKV65 RS04535
gene id: 158847:CKV65_RS04535
uniprot id: A0A239TKU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

158847:CKV65 RS02820
gene id: 158847:CKV65_RS02820
uniprot id: A0A239TFC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

158847:CKV65 RS05615
gene id: 158847:CKV65_RS05615
uniprot id: A0A239TPZ1
names: Similarity
messages: Belongs to the PRORSD1 family.

158847:CKV65 RS04595
gene id: 158847:CKV65_RS04595
uniprot id: A0A239TL01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158847:CKV65 RS06100
gene id: 158847:CKV65_RS06100
uniprot id: A0A239TT72
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158847:CKV65 RS04990
gene id: 158847:CKV65_RS04990
uniprot id: A0A239TM99
names: Similarity
messages: Belongs to the UPF0597 family.

158847:CKV65 RS09255
gene id: 158847:CKV65_RS09255
uniprot id: A0A239U232
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

158847:CKV65 RS10165
gene id: 158847:CKV65_RS10165
uniprot id: A0A239U4V4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

158847:CKV65 RS01315
gene id: 158847:CKV65_RS01315
uniprot id: A0A239TD99
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS07695
gene id: 158847:CKV65_RS07695
uniprot id: A0A239TXH4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

158847:CKV65 RS06655
gene id: 158847:CKV65_RS06655
uniprot id: A0A239TV73
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

158847:CKV65 RS00210
gene id: 158847:CKV65_RS00210
uniprot id: A0A239T7C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

158847:CKV65 RS03140
gene id: 158847:CKV65_RS03140
uniprot id: A0A239TGI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

158847:CKV65 RS05100
gene id: 158847:CKV65_RS05100
uniprot id: A0A239TQI6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

158847:CKV65 RS08045
gene id: 158847:CKV65_RS08045
uniprot id: A0A239TYI2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

158847:CKV65 RS07465
gene id: 158847:CKV65_RS07465
uniprot id: A0A239TXA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

158847:CKV65 RS01705
gene id: 158847:CKV65_RS01705
uniprot id: A0A239TBV3
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

158847:CKV65 RS03860
gene id: 158847:CKV65_RS03860
uniprot id: A0A239TIP4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158847:CKV65 RS02275
gene id: 158847:CKV65_RS02275
uniprot id: A0A239TDT5
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

158847:CKV65 RS00620
gene id: 158847:CKV65_RS00620
uniprot id: A0A239T8D5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

158847:CKV65 RS01425
gene id: 158847:CKV65_RS01425
uniprot id: A0A239TDQ4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

158847:CKV65 RS06550
gene id: 158847:CKV65_RS06550
uniprot id: A0A239TT28
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

158847:CKV65 RS06835
gene id: 158847:CKV65_RS06835
uniprot id: A0A239TT79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

158847:CKV65 RS07575
gene id: 158847:CKV65_RS07575
uniprot id: A0A239TWJ6
names: Similarity
messages: Belongs to the ribF family.

158847:CKV65 RS08135
gene id: 158847:CKV65_RS08135
uniprot id: A0A239U024
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS05660
gene id: 158847:CKV65_RS05660
uniprot id: A0A239TS31
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS09250
gene id: 158847:CKV65_RS09250
uniprot id: A0A239U1S2
names: Similarity
messages: Belongs to the CobT family.

158847:CKV65 RS09065
gene id: 158847:CKV65_RS09065
uniprot id: A0A239U2V5
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

158847:CKV65 RS10570
gene id: 158847:CKV65_RS10570
uniprot id: A0A239U5Z9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS03605
gene id: 158847:CKV65_RS03605
uniprot id: A0A239THP9
names: Similarity
messages: Belongs to the acylphosphatase family.

158847:CKV65 RS10460
gene id: 158847:CKV65_RS10460
uniprot id: A0A239U7B2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

158847:CKV65 RS03155
gene id: 158847:CKV65_RS03155
uniprot id: A0A239TGW8
names: Similarity
messages: Belongs to the glycosyl hydrolase.

158847:CKV65 RS05910
gene id: 158847:CKV65_RS05910
uniprot id: A0A239TQT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

158847:CKV65 RS07075
gene id: 158847:CKV65_RS07075
uniprot id: A0A239TXP8
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

158847:CKV65 RS01565
gene id: 158847:CKV65_RS01565
uniprot id: A0A239TDZ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS03345
gene id: 158847:CKV65_RS03345
uniprot id: A0A239TJG5
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

158847:CKV65 RS09930
gene id: 158847:CKV65_RS09930
uniprot id: A0A239U3K4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS01595
gene id: 158847:CKV65_RS01595
uniprot id: A0A239TC91
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

158847:CKV65 RS09325
gene id: 158847:CKV65_RS09325
uniprot id: A0A239U3H8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

158847:CKV65 RS03080
gene id: 158847:CKV65_RS03080
uniprot id: A0A239TIY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

158847:CKV65 RS06265
gene id: 158847:CKV65_RS06265
uniprot id: A0A239TS56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

158847:CKV65 RS08515
gene id: 158847:CKV65_RS08515
uniprot id: A0A239U0W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

158847:CKV65 RS10535
gene id: 158847:CKV65_RS10535
uniprot id: A0A239U637
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS08675
gene id: 158847:CKV65_RS08675
uniprot id: A0A239U1Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

158847:CKV65 RS00185
gene id: 158847:CKV65_RS00185
uniprot id: A0A239T7A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

158847:CKV65 RS05435
gene id: 158847:CKV65_RS05435
uniprot id: A0A239TPQ4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

158847:CKV65 RS02235
gene id: 158847:CKV65_RS02235
uniprot id: A0A239TD67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

158847:CKV65 RS07265
gene id: 158847:CKV65_RS07265
uniprot id: A0A239TW50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

158847:CKV65 RS05080
gene id: 158847:CKV65_RS05080
uniprot id: A0A239TMV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

158847:CKV65 RS00180
gene id: 158847:CKV65_RS00180
uniprot id: A0A239T7P4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

158847:CKV65 RS07770
gene id: 158847:CKV65_RS07770
uniprot id: A0A239TY66
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS02865
gene id: 158847:CKV65_RS02865
uniprot id: A0A239TFV5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS00355
gene id: 158847:CKV65_RS00355
uniprot id: A0A239T7P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

158847:CKV65 RS04490
gene id: 158847:CKV65_RS04490
uniprot id: A0A239TKE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

158847:CKV65 RS09440
gene id: 158847:CKV65_RS09440
uniprot id: A0A239U239
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

158847:CKV65 RS04840
gene id: 158847:CKV65_RS04840
uniprot id: A0A239TMU2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

158847:CKV65 RS07030
gene id: 158847:CKV65_RS07030
uniprot id: A0A239TV95
names: Similarity
messages: Belongs to the CFA/CMAS family.

158847:CKV65 RS07645
gene id: 158847:CKV65_RS07645
uniprot id: A0A239TZP9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

158847:CKV65 RS05780
gene id: 158847:CKV65_RS05780
uniprot id: A0A239TQ03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

158847:CKV65 RS10040
gene id: 158847:CKV65_RS10040
uniprot id: A0A239U491
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

158847:CKV65 RS08235
gene id: 158847:CKV65_RS08235
uniprot id: A0A239U0A1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

158847:CKV65 RS07355
gene id: 158847:CKV65_RS07355
uniprot id: A0A239TVQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

158847:CKV65 RS02760
gene id: 158847:CKV65_RS02760
uniprot id: A0A239TFJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

158847:CKV65 RS07445
gene id: 158847:CKV65_RS07445
uniprot id: A0A239TWS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

158847:CKV65 RS09615
gene id: 158847:CKV65_RS09615
uniprot id: A0A239U368
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

158847:CKV65 RS05525
gene id: 158847:CKV65_RS05525
uniprot id: A0A239TPN5
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS00715
gene id: 158847:CKV65_RS00715
uniprot id: A0A239T8P5
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

158847:CKV65 RS06085
gene id: 158847:CKV65_RS06085
uniprot id: A0A239TQK7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

158847:CKV65 RS08105
gene id: 158847:CKV65_RS08105
uniprot id: A0A239TYR9
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

158847:CKV65 RS09285
gene id: 158847:CKV65_RS09285
uniprot id: A0A921L838
names: Caution
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

158847:CKV65 RS09470
gene id: 158847:CKV65_RS09470
uniprot id: A0A239U1V5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

158847:CKV65 RS10665
gene id: 158847:CKV65_RS10665
uniprot id: A0A239U6T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS07435
gene id: 158847:CKV65_RS07435
uniprot id: A0A239TZ25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

158847:CKV65 RS03070
gene id: 158847:CKV65_RS03070
uniprot id: A0A239TGI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

158847:CKV65 RS02245
gene id: 158847:CKV65_RS02245
uniprot id: A0A239TDL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

158847:CKV65 RS06855
gene id: 158847:CKV65_RS06855
uniprot id: A0A239TUM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

158847:CKV65 RS04440
gene id: 158847:CKV65_RS04440
uniprot id: A0A239TL51
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS04585
gene id: 158847:CKV65_RS04585
uniprot id: A0A239TNS9
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

158847:CKV65 RS01365
gene id: 158847:CKV65_RS01365
uniprot id: A0A239TDH7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS09290
gene id: 158847:CKV65_RS09290
uniprot id: A0A239U268
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS03805
gene id: 158847:CKV65_RS03805
uniprot id: A0A239TIH3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

158847:CKV65 RS08500
gene id: 158847:CKV65_RS08500
uniprot id: A0A239TZM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

158847:CKV65 RS00245
gene id: 158847:CKV65_RS00245
uniprot id: A0A239T9M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

158847:CKV65 RS09410
gene id: 158847:CKV65_RS09410
uniprot id: A0A239U237
names: Similarity
messages: Belongs to the EamA transporter family.

158847:CKV65 RS09775
gene id: 158847:CKV65_RS09775
uniprot id: A0A239U3G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS08830
gene id: 158847:CKV65_RS08830
uniprot id: A0A239U104
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS07200
gene id: 158847:CKV65_RS07200
uniprot id: A0A239TWW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

158847:CKV65 RS09160
gene id: 158847:CKV65_RS09160
uniprot id: A0A239U1T3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

158847:CKV65 RS07875
gene id: 158847:CKV65_RS07875
uniprot id: A0A239TYJ2
names: Similarity
messages: Belongs to the CobH/CbiC family.

158847:CKV65 RS03510
gene id: 158847:CKV65_RS03510
uniprot id: A0A239TKQ3
names: Similarity
messages: Belongs to the asp23 family.

158847:CKV65 RS06780
gene id: 158847:CKV65_RS06780
uniprot id: A0A239TW40
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

158847:CKV65 RS04625
gene id: 158847:CKV65_RS04625
uniprot id: A0A239TLQ9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

158847:CKV65 RS06645
gene id: 158847:CKV65_RS06645
uniprot id: A0A239TTD8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

158847:CKV65 RS04035
gene id: 158847:CKV65_RS04035
uniprot id: A0A239TJB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

158847:CKV65 RS04280
gene id: 158847:CKV65_RS04280
uniprot id: A0A239TJR2
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

158847:CKV65 RS06500
gene id: 158847:CKV65_RS06500
uniprot id: A0A239TST2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

158847:CKV65 RS07670
gene id: 158847:CKV65_RS07670
uniprot id: A0A239TYG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

158847:CKV65 RS02860
gene id: 158847:CKV65_RS02860
uniprot id: A0A239TFS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

158847:CKV65 RS05405
gene id: 158847:CKV65_RS05405
uniprot id: A0A239TPC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

158847:CKV65 RS06640
gene id: 158847:CKV65_RS06640
uniprot id: A0A239TV57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS06205
gene id: 158847:CKV65_RS06205
uniprot id: A0A239TSV7
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS06020
gene id: 158847:CKV65_RS06020
uniprot id: A0A239TSZ0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

158847:CKV65 RS03210
gene id: 158847:CKV65_RS03210
uniprot id: A0A239TJP1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

158847:CKV65 RS09175
gene id: 158847:CKV65_RS09175
uniprot id: A0A239U1U8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

158847:CKV65 RS05175
gene id: 158847:CKV65_RS05175
uniprot id: A0A239TP02
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS05280
gene id: 158847:CKV65_RS05280
uniprot id: A0A239TNJ1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

158847:CKV65 RS09705
gene id: 158847:CKV65_RS09705
uniprot id: A0A239U382
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

158847:CKV65 RS09970
gene id: 158847:CKV65_RS09970
uniprot id: A0A239U536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

158847:CKV65 RS10030
gene id: 158847:CKV65_RS10030
uniprot id: A0A239U482
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

158847:CKV65 RS05605
gene id: 158847:CKV65_RS05605
uniprot id: A0A239TSK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

158847:CKV65 RS07895
gene id: 158847:CKV65_RS07895
uniprot id: A0A239TYL3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

158847:CKV65 RS07460
gene id: 158847:CKV65_RS07460
uniprot id: A0A239TWT6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

158847:CKV65 RS10670
gene id: 158847:CKV65_RS10670
uniprot id: A0A239U7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS05295
gene id: 158847:CKV65_RS05295
uniprot id: A0A239TN07
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

158847:CKV65 RS08075
gene id: 158847:CKV65_RS08075
uniprot id: A0A239U0R1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS00340
gene id: 158847:CKV65_RS00340
uniprot id: A0A239TA50
names: Similarity
messages: Belongs to the stealth family.

158847:CKV65 RS07210
gene id: 158847:CKV65_RS07210
uniprot id: A0A239TY94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

158847:CKV65 RS00935
gene id: 158847:CKV65_RS00935
uniprot id: A0A239T9V8
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS10445
gene id: 158847:CKV65_RS10445
uniprot id: A0A239U5S5
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

158847:CKV65 RS01135
gene id: 158847:CKV65_RS01135
uniprot id: A0A239TC99
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

158847:CKV65 RS03280
gene id: 158847:CKV65_RS03280
uniprot id: A0A239THK6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

158847:CKV65 RS00485
gene id: 158847:CKV65_RS00485
uniprot id: A0A239TA80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

158847:CKV65 RS06540
gene id: 158847:CKV65_RS06540
uniprot id: A0A239TSJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS03230
gene id: 158847:CKV65_RS03230
uniprot id: A0A239TI18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS02895
gene id: 158847:CKV65_RS02895
uniprot id: A0A239TIC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS07375
gene id: 158847:CKV65_RS07375
uniprot id: A0A239TWI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

158847:CKV65 RS09050
gene id: 158847:CKV65_RS09050
uniprot id: A0A239U117
names: Similarity
messages: Belongs to the HypE family.

158847:CKV65 RS07735
gene id: 158847:CKV65_RS07735
uniprot id: A0A239U003
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

158847:CKV65 RS02015
gene id: 158847:CKV65_RS02015
uniprot id: A0A239TCK6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS05500
gene id: 158847:CKV65_RS05500
uniprot id: A0A239TRK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS09395
gene id: 158847:CKV65_RS09395
uniprot id: A0A239U503
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

158847:CKV65 RS07395
gene id: 158847:CKV65_RS07395
uniprot id: A0A239TYZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

158847:CKV65 RS01960
gene id: 158847:CKV65_RS01960
uniprot id: A0A239TD26
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

158847:CKV65 RS07775
gene id: 158847:CKV65_RS07775
uniprot id: A0A239TX27
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS04435
gene id: 158847:CKV65_RS04435
uniprot id: A0A239TNA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

158847:CKV65 RS10190
gene id: 158847:CKV65_RS10190
uniprot id: A0A239U4S7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS06545
gene id: 158847:CKV65_RS06545
uniprot id: A0A239TT10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

158847:CKV65 RS04860
gene id: 158847:CKV65_RS04860
uniprot id: A0A239TQE3
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS04265
gene id: 158847:CKV65_RS04265
uniprot id: A0A239TMN9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

158847:CKV65 RS05130
gene id: 158847:CKV65_RS05130
uniprot id: A0A239TMH7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS01930
gene id: 158847:CKV65_RS01930
uniprot id: A0A239TCE8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

158847:CKV65 RS04315
gene id: 158847:CKV65_RS04315
uniprot id: A0A239TL42
names: Similarity
messages: Belongs to the glutamine synthetase family.

158847:CKV65 RS09145
gene id: 158847:CKV65_RS09145
uniprot id: A0A239U305
names: Similarity
messages: Belongs to the peptidase M18 family.

158847:CKV65 RS02195
gene id: 158847:CKV65_RS02195
uniprot id: A0A239TD25
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

158847:CKV65 RS02315
gene id: 158847:CKV65_RS02315
uniprot id: A0A239TDX0
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

158847:CKV65 RS08055
gene id: 158847:CKV65_RS08055
uniprot id: A0A239U0M7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

158847:CKV65 RS05480
gene id: 158847:CKV65_RS05480
uniprot id: A0A239TQL5
names: Similarity
messages: Belongs to the UPF0749 family.

158847:CKV65 RS01905
gene id: 158847:CKV65_RS01905
uniprot id: A0A239TCY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

158847:CKV65 RS05760
gene id: 158847:CKV65_RS05760
uniprot id: A0A239TQD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

158847:CKV65 RS04105
gene id: 158847:CKV65_RS04105
uniprot id: A0A239TJ72
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

158847:CKV65 RS04065
gene id: 158847:CKV65_RS04065
uniprot id: A0A239TKC9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

158847:CKV65 RS06270
gene id: 158847:CKV65_RS06270
uniprot id: A0A239TTV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

158847:CKV65 RS03630
gene id: 158847:CKV65_RS03630
uniprot id: A0A239TJG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

158847:CKV65 RS03660
gene id: 158847:CKV65_RS03660
uniprot id: A0A239TIQ3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

158847:CKV65 RS01870
gene id: 158847:CKV65_RS01870
uniprot id: A0A239TCQ8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

158847:CKV65 RS08195
gene id: 158847:CKV65_RS08195
uniprot id: A0A239TYI6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

158847:CKV65 RS00890
gene id: 158847:CKV65_RS00890
uniprot id: A0A239T9Q9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS02035
gene id: 158847:CKV65_RS02035
uniprot id: A0A239TEA9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

158847:CKV65 RS00405
gene id: 158847:CKV65_RS00405
uniprot id: A0A239T9Q8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

158847:CKV65 RS08520
gene id: 158847:CKV65_RS08520
uniprot id: A0A239U0B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

158847:CKV65 RS04230
gene id: 158847:CKV65_RS04230
uniprot id: A0A239TKF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

158847:CKV65 RS04295
gene id: 158847:CKV65_RS04295
uniprot id: A0A239TL14
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS08965
gene id: 158847:CKV65_RS08965
uniprot id: A0A239U136
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS01830
gene id: 158847:CKV65_RS01830
uniprot id: A0A239TCM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

158847:CKV65 RS01340
gene id: 158847:CKV65_RS01340
uniprot id: A0A239TDM4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS03835
gene id: 158847:CKV65_RS03835
uniprot id: A0A239TIQ0
names: Similarity
messages: Belongs to the pyruvate kinase family.

158847:CKV65 RS01775
gene id: 158847:CKV65_RS01775
uniprot id: A0A239TC19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BioW family.
messages: Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
messages: Homodimer.

158847:CKV65 RS01200
gene id: 158847:CKV65_RS01200
uniprot id: A0A239TCR6
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

158847:CKV65 RS00230
gene id: 158847:CKV65_RS00230
uniprot id: A0A239T7D8
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

158847:CKV65 RS03590
gene id: 158847:CKV65_RS03590
uniprot id: A0A239THZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

158847:CKV65 RS02945
gene id: 158847:CKV65_RS02945
uniprot id: A0A239TII0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

158847:CKV65 RS09620
gene id: 158847:CKV65_RS09620
uniprot id: A0A239U4G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

158847:CKV65 RS05470
gene id: 158847:CKV65_RS05470
uniprot id: A0A239TNJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

158847:CKV65 RS00080
gene id: 158847:CKV65_RS00080
uniprot id: A0A239T7L1
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

158847:CKV65 RS06530
gene id: 158847:CKV65_RS06530
uniprot id: A0A239TUK8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

158847:CKV65 RS07225
gene id: 158847:CKV65_RS07225
uniprot id: A0A239TXT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

158847:CKV65 RS00980
gene id: 158847:CKV65_RS00980
uniprot id: A0A239T9T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

158847:CKV65 RS06505
gene id: 158847:CKV65_RS06505
uniprot id: A0A239TV43
names: Similarity
messages: Belongs to the fabD family.

158847:CKV65 RS09675
gene id: 158847:CKV65_RS09675
uniprot id: A0A239U5Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS10035
gene id: 158847:CKV65_RS10035
uniprot id: A0A239U4R1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

158847:CKV65 RS00430
gene id: 158847:CKV65_RS00430
uniprot id: A0A239T7V6
names: Similarity
messages: Belongs to the GPI family.

158847:CKV65 RS00880
gene id: 158847:CKV65_RS00880
uniprot id: A0A239T9S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

158847:CKV65 RS09315
gene id: 158847:CKV65_RS09315
uniprot id: A0A239U3G9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS09940
gene id: 158847:CKV65_RS09940
uniprot id: A0A239U6W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

158847:CKV65 RS09015
gene id: 158847:CKV65_RS09015
uniprot id: A0A239U0Y1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

158847:CKV65 RS02200
gene id: 158847:CKV65_RS02200
uniprot id: A0A239TD64
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

158847:CKV65 RS04015
gene id: 158847:CKV65_RS04015
uniprot id: A0A239TLW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

158847:CKV65 RS01090
gene id: 158847:CKV65_RS01090
uniprot id: A0A239T9Y1
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS07370
gene id: 158847:CKV65_RS07370
uniprot id: A0A239TYF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

158847:CKV65 RS07310
gene id: 158847:CKV65_RS07310
uniprot id: A0A239TY62
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

158847:CKV65 RS08125
gene id: 158847:CKV65_RS08125
uniprot id: A0A239U186
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS05640
gene id: 158847:CKV65_RS05640
uniprot id: A0A239TSR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS09310
gene id: 158847:CKV65_RS09310
uniprot id: A0A239U4S0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

158847:CKV65 RS05845
gene id: 158847:CKV65_RS05845
uniprot id: A0A239TPL4
names: Similarity
messages: Belongs to the Ahb/Nir family.

158847:CKV65 RS01000
gene id: 158847:CKV65_RS01000
uniprot id: A0A239T9F1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

158847:CKV65 RS02115
gene id: 158847:CKV65_RS02115
uniprot id: A0A239TCV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

158847:CKV65 RS00125
gene id: 158847:CKV65_RS00125
uniprot id: A0A239T9M1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

158847:CKV65 RS07305
gene id: 158847:CKV65_RS07305
uniprot id: A0A239TVZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

158847:CKV65 RS07255
gene id: 158847:CKV65_RS07255
uniprot id: A0A239TVS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

158847:CKV65 RS00995
gene id: 158847:CKV65_RS00995
uniprot id: A0A239T9E2
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS03635
gene id: 158847:CKV65_RS03635
uniprot id: A0A239TKN5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

158847:CKV65 RS03445
gene id: 158847:CKV65_RS03445
uniprot id: A0A239THF6
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

158847:CKV65 RS03585
gene id: 158847:CKV65_RS03585
uniprot id: A0A239THN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

158847:CKV65 RS07985
gene id: 158847:CKV65_RS07985
uniprot id: A0A239TYC5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

158847:CKV65 RS07610
gene id: 158847:CKV65_RS07610
uniprot id: A0A239TXB1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

158847:CKV65 RS07230
gene id: 158847:CKV65_RS07230
uniprot id: A0A239TV68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

158847:CKV65 RS05870
gene id: 158847:CKV65_RS05870
uniprot id: A0A239TQ95
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

158847:CKV65 RS10440
gene id: 158847:CKV65_RS10440
uniprot id: A0A239U5S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS05925
gene id: 158847:CKV65_RS05925
uniprot id: A0A239TQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS03190
gene id: 158847:CKV65_RS03190
uniprot id: A0A239TGG0
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

158847:CKV65 RS07455
gene id: 158847:CKV65_RS07455
uniprot id: A0A239TWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

158847:CKV65 RS06720
gene id: 158847:CKV65_RS06720
uniprot id: A0A239TWD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

158847:CKV65 RS03355
gene id: 158847:CKV65_RS03355
uniprot id: A0A239THC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS02875
gene id: 158847:CKV65_RS02875
uniprot id: A0A239TI95
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

158847:CKV65 RS09415
gene id: 158847:CKV65_RS09415
uniprot id: A0A239U293
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

158847:CKV65 RS05255
gene id: 158847:CKV65_RS05255
uniprot id: A0A239TNT7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

158847:CKV65 RS03720
gene id: 158847:CKV65_RS03720
uniprot id: A0A239TID2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

158847:CKV65 RS08010
gene id: 158847:CKV65_RS08010
uniprot id: A0A239TYZ5
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

158847:CKV65 RS09095
gene id: 158847:CKV65_RS09095
uniprot id: A0A239U2A6
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

158847:CKV65 RS09060
gene id: 158847:CKV65_RS09060
uniprot id: A0A239U1L5
names: Similarity
messages: Belongs to the HupF/HypC family.

158847:CKV65 RS02365
gene id: 158847:CKV65_RS02365
uniprot id: A0A239TG93
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

158847:CKV65 RS01900
gene id: 158847:CKV65_RS01900
uniprot id: A0A239TCB7
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

158847:CKV65 RS02335
gene id: 158847:CKV65_RS02335
uniprot id: A0A239TDW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

158847:CKV65 RS07585
gene id: 158847:CKV65_RS07585
uniprot id: A0A239TW26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

158847:CKV65 RS02755
gene id: 158847:CKV65_RS02755
uniprot id: A0A239THD1
names: Similarity
messages: Belongs to the DprA/Smf family.

158847:CKV65 RS08510
gene id: 158847:CKV65_RS08510
uniprot id: A0A239U2G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

158847:CKV65 RS02285
gene id: 158847:CKV65_RS02285
uniprot id: A0A239TDU7
names: Similarity
messages: Belongs to the transpeptidase family.

158847:CKV65 RS05235
gene id: 158847:CKV65_RS05235
uniprot id: A0A239TMT9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

158847:CKV65 RS06560
gene id: 158847:CKV65_RS06560
uniprot id: A0A239TRS7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

158847:CKV65 RS06145
gene id: 158847:CKV65_RS06145
uniprot id: A0A239TQP4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

158847:CKV65 RS00705
gene id: 158847:CKV65_RS00705
uniprot id: A0A239T8N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

158847:CKV65 RS08900
gene id: 158847:CKV65_RS08900
uniprot id: A0A239U0L3
names: Similarity
messages: Belongs to the glutamate synthase family.

158847:CKV65 RS01465
gene id: 158847:CKV65_RS01465
uniprot id: A0A239TBZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

158847:CKV65 RS05245
gene id: 158847:CKV65_RS05245
uniprot id: A0A239TMU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

158847:CKV65 RS02830
gene id: 158847:CKV65_RS02830
uniprot id: A0A239TFR5
names: Similarity
messages: Belongs to the peptidase M18 family.

158847:CKV65 RS03110
gene id: 158847:CKV65_RS03110
uniprot id: A0A239TG71
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

158847:CKV65 RS03640
gene id: 158847:CKV65_RS03640
uniprot id: A0A239TIV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS00470
gene id: 158847:CKV65_RS00470
uniprot id: A0A239TAG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

158847:CKV65 RS08215
gene id: 158847:CKV65_RS08215
uniprot id: A0A239TZN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS02525
gene id: 158847:CKV65_RS02525
uniprot id: A0A239TFP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

158847:CKV65 RS02815
gene id: 158847:CKV65_RS02815
uniprot id: A0A239TF98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

158847:CKV65 RS04605
gene id: 158847:CKV65_RS04605
uniprot id: A0A239TL86
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

158847:CKV65 RS09700
gene id: 158847:CKV65_RS09700
uniprot id: A0A239U3J3
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS08250
gene id: 158847:CKV65_RS08250
uniprot id: A0A239U187
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

158847:CKV65 RS05555
gene id: 158847:CKV65_RS05555
uniprot id: A0A239TQS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

158847:CKV65 RS03525
gene id: 158847:CKV65_RS03525
uniprot id: A0A239THY1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

158847:CKV65 RS06150
gene id: 158847:CKV65_RS06150
uniprot id: A0A239TTD3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

158847:CKV65 RS02325
gene id: 158847:CKV65_RS02325
uniprot id: A0A239TFU7
names: Similarity
messages: Belongs to the glycosyl hydrolase.

158847:CKV65 RS06485
gene id: 158847:CKV65_RS06485
uniprot id: A0A239TSS1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

158847:CKV65 RS07330
gene id: 158847:CKV65_RS07330
uniprot id: A0A239TVL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

158847:CKV65 RS00025
gene id: 158847:CKV65_RS00025
uniprot id: A0A239T6U8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

158847:CKV65 RS04750
gene id: 158847:CKV65_RS04750
uniprot id: A0A239TQ18
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158847:CKV65 RS10605
gene id: 158847:CKV65_RS10605
uniprot id: A0A239U6I3
names: Similarity
messages: Belongs to the universal stress protein A family.

158847:CKV65 RS00455
gene id: 158847:CKV65_RS00455
uniprot id: A0A239T8M4
names: Similarity
messages: Belongs to the UPF0234 family.

158847:CKV65 RS07095
gene id: 158847:CKV65_RS07095
uniprot id: A0A239TWH4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

158847:CKV65 RS07580
gene id: 158847:CKV65_RS07580
uniprot id: A0A239TZ94
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

158847:CKV65 RS02050
gene id: 158847:CKV65_RS02050
uniprot id: A0A239TCN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

158847:CKV65 RS10645
gene id: 158847:CKV65_RS10645
uniprot id: A0A239U5X5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

158847:CKV65 RS01895
gene id: 158847:CKV65_RS01895
uniprot id: A0A239TET2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

158847:CKV65 RS03565
gene id: 158847:CKV65_RS03565
uniprot id: A0A239THL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

158847:CKV65 RS06595
gene id: 158847:CKV65_RS06595
uniprot id: A0A239TU98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

158847:CKV65 RS06495
gene id: 158847:CKV65_RS06495
uniprot id: A0A239TSL8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

158847:CKV65 RS05290
gene id: 158847:CKV65_RS05290
uniprot id: A0A239TP34
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

158847:CKV65 RS03865
gene id: 158847:CKV65_RS03865
uniprot id: A0A239TJA3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

158847:CKV65 RS03830
gene id: 158847:CKV65_RS03830
uniprot id: A0A239TLV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

158847:CKV65 RS02410
gene id: 158847:CKV65_RS02410
uniprot id: A0A239TDV6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

158847:CKV65 RS00370
gene id: 158847:CKV65_RS00370
uniprot id: A0A239T9N2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

158847:CKV65 RS00960
gene id: 158847:CKV65_RS00960
uniprot id: A0A239T9A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

158847:CKV65 RS10565
gene id: 158847:CKV65_RS10565
uniprot id: A0A239U6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

158847:CKV65 RS09075
gene id: 158847:CKV65_RS09075
uniprot id: A0A239U450
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

158847:CKV65 RS10585
gene id: 158847:CKV65_RS10585
uniprot id: A0A239U900
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

158847:CKV65 RS06960
gene id: 158847:CKV65_RS06960
uniprot id: A0A239TXF6
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS09345
gene id: 158847:CKV65_RS09345
uniprot id: A0A239U2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

158847:CKV65 RS02025
gene id: 158847:CKV65_RS02025
uniprot id: A0A239TCL6
names: Similarity
messages: Belongs to the EamA transporter family.

158847:CKV65 RS10515
gene id: 158847:CKV65_RS10515
uniprot id: A0A239U606
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

158847:CKV65 RS01860
gene id: 158847:CKV65_RS01860
uniprot id: A0A239TC83
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

158847:CKV65 RS02265
gene id: 158847:CKV65_RS02265
uniprot id: A0A239TDC3
names: Similarity
messages: Belongs to the UPF0758 family.

158847:CKV65 RS01700
gene id: 158847:CKV65_RS01700
uniprot id: A0A239TBW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

158847:CKV65 RS03780
gene id: 158847:CKV65_RS03780
uniprot id: A0A239TI60
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

158847:CKV65 RS03785
gene id: 158847:CKV65_RS03785
uniprot id: A0A239TIP8
names: Similarity
messages: Belongs to the YoeB family.

158847:CKV65 RS00255
gene id: 158847:CKV65_RS00255
uniprot id: A0A239T7G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

158847:CKV65 RS04030
gene id: 158847:CKV65_RS04030
uniprot id: A0A239TMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

158847:CKV65 RS05520
gene id: 158847:CKV65_RS05520
uniprot id: A0A239TNN5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS08680
gene id: 158847:CKV65_RS08680
uniprot id: A0A239U2W9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

158847:CKV65 RS10420
gene id: 158847:CKV65_RS10420
uniprot id: A0A239U5H9
names: Similarity
messages: Belongs to the Skp family.

158847:CKV65 RS06515
gene id: 158847:CKV65_RS06515
uniprot id: A0A239TRU6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

158847:CKV65 RS07320
gene id: 158847:CKV65_RS07320
uniprot id: A0A239TYN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

158847:CKV65 RS03455
gene id: 158847:CKV65_RS03455
uniprot id: A0A239TIU3
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS08685
gene id: 158847:CKV65_RS08685
uniprot id: A0A239U1Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

158847:CKV65 RS01430
gene id: 158847:CKV65_RS01430
uniprot id: A0A239TBA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

158847:CKV65 RS00015
gene id: 158847:CKV65_RS00015
uniprot id: A0A239T764
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS08735
gene id: 158847:CKV65_RS08735
uniprot id: A0A239U0E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

158847:CKV65 RS01875
gene id: 158847:CKV65_RS01875
uniprot id: A0A239TCA2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

158847:CKV65 RS08095
gene id: 158847:CKV65_RS08095
uniprot id: A0A239TZA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

158847:CKV65 RS07345
gene id: 158847:CKV65_RS07345
uniprot id: A0A239TVN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

158847:CKV65 RS05285
gene id: 158847:CKV65_RS05285
uniprot id: A0A239TPB7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

158847:CKV65 RS06455
gene id: 158847:CKV65_RS06455
uniprot id: A0A239TS42
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

158847:CKV65 RS10690
gene id: 158847:CKV65_RS10690
uniprot id: A0A239U6V7
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS04270
gene id: 158847:CKV65_RS04270
uniprot id: A0A239TK22
names: Similarity
messages: Belongs to the SAICAR synthetase family.

158847:CKV65 RS07270
gene id: 158847:CKV65_RS07270
uniprot id: A0A239TWF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

158847:CKV65 RS08660
gene id: 158847:CKV65_RS08660
uniprot id: A0A239U355
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

158847:CKV65 RS04205
gene id: 158847:CKV65_RS04205
uniprot id: A0A239TLD4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS03945
gene id: 158847:CKV65_RS03945
uniprot id: A0A239TKH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusB family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

158847:CKV65 RS09860
gene id: 158847:CKV65_RS09860
uniprot id: A0A239U3N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

158847:CKV65 RS09235
gene id: 158847:CKV65_RS09235
uniprot id: A0A239U203
names: Similarity
messages: Belongs to the peptidase S11 family.

158847:CKV65 RS00110
gene id: 158847:CKV65_RS00110
uniprot id: A0A239T9K1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

158847:CKV65 RS04925
gene id: 158847:CKV65_RS04925
uniprot id: A0A239TN03
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

158847:CKV65 RS06825
gene id: 158847:CKV65_RS06825
uniprot id: A0A239TTP9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

158847:CKV65 RS07190
gene id: 158847:CKV65_RS07190
uniprot id: A0A239TXN5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

158847:CKV65 RS00055
gene id: 158847:CKV65_RS00055
uniprot id: A0A239T7I9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

158847:CKV65 RS10415
gene id: 158847:CKV65_RS10415
uniprot id: A0A239U8G0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS04145
gene id: 158847:CKV65_RS04145
uniprot id: A0A239TMY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

158847:CKV65 RS02040
gene id: 158847:CKV65_RS02040
uniprot id: A0A239TCP1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

158847:CKV65 RS06300
gene id: 158847:CKV65_RS06300
uniprot id: A0A239TS22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

158847:CKV65 RS06320
gene id: 158847:CKV65_RS06320
uniprot id: A0A239TUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

158847:CKV65 RS05855
gene id: 158847:CKV65_RS05855
uniprot id: A0A239TPM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

158847:CKV65 RS07195
gene id: 158847:CKV65_RS07195
uniprot id: A0A239TVU6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

158847:CKV65 RS05685
gene id: 158847:CKV65_RS05685
uniprot id: A0A239TP65
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS01450
gene id: 158847:CKV65_RS01450
uniprot id: A0A239TBC3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS07145
gene id: 158847:CKV65_RS07145
uniprot id: A0A239TVT4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

158847:CKV65 RS05790
gene id: 158847:CKV65_RS05790
uniprot id: A0A239TPP2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

158847:CKV65 RS02330
gene id: 158847:CKV65_RS02330
uniprot id: A0A239TDK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS06860
gene id: 158847:CKV65_RS06860
uniprot id: A0A239TTA9
names: Similarity
messages: Belongs to the type IA topoisomerase family.

158847:CKV65 RS00170
gene id: 158847:CKV65_RS00170
uniprot id: A0A239T7N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

158847:CKV65 RS06590
gene id: 158847:CKV65_RS06590
uniprot id: A0A239TVN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

158847:CKV65 RS01755
gene id: 158847:CKV65_RS01755
uniprot id: A0A239TEG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

158847:CKV65 RS08495
gene id: 158847:CKV65_RS08495
uniprot id: A0A239U088
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

158847:CKV65 RS01540
gene id: 158847:CKV65_RS01540
uniprot id: A0A239TBZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

158847:CKV65 RS01850
gene id: 158847:CKV65_RS01850
uniprot id: A0A239TCU4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

158847:CKV65 RS01955
gene id: 158847:CKV65_RS01955
uniprot id: A0A239TCG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

158847:CKV65 RS05675
gene id: 158847:CKV65_RS05675
uniprot id: A0A239TP56
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

158847:CKV65 RS06715
gene id: 158847:CKV65_RS06715
uniprot id: A0A239TT66
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

158847:CKV65 RS05830
gene id: 158847:CKV65_RS05830
uniprot id: A0A239TQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

158847:CKV65 RS02715
gene id: 158847:CKV65_RS02715
uniprot id: A0A239TEZ1
names: Similarity
messages: Belongs to the peptidase M20A family.

158847:CKV65 RS02030
gene id: 158847:CKV65_RS02030
uniprot id: A0A239TF48
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS05515
gene id: 158847:CKV65_RS05515
uniprot id: A0A239TNV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

158847:CKV65 RS04445
gene id: 158847:CKV65_RS04445
uniprot id: A0A239TMA3
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

158847:CKV65 RS09180
gene id: 158847:CKV65_RS09180
uniprot id: A0A239U1E6
names: Similarity
messages: Belongs to the peptidase S16 family.

158847:CKV65 RS03545
gene id: 158847:CKV65_RS03545
uniprot id: A0A239THT5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

158847:CKV65 RS09580
gene id: 158847:CKV65_RS09580
uniprot id: A0A239U3P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

158847:CKV65 RS00205
gene id: 158847:CKV65_RS00205
uniprot id: A0A239T820
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

158847:CKV65 RS06775
gene id: 158847:CKV65_RS06775
uniprot id: A0A239TUI9
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

158847:CKV65 RS01935
gene id: 158847:CKV65_RS01935
uniprot id: A0A239TEX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

158847:CKV65 RS09120
gene id: 158847:CKV65_RS09120
uniprot id: A0A239U2D3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

158847:CKV65 RS03435
gene id: 158847:CKV65_RS03435
uniprot id: A0A239THF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

158847:CKV65 RS01095
gene id: 158847:CKV65_RS01095
uniprot id: A0A239TAE4
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS09210
gene id: 158847:CKV65_RS09210
uniprot id: A0A239U1D9
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

158847:CKV65 RS06355
gene id: 158847:CKV65_RS06355
uniprot id: A0A239TUQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS00945
gene id: 158847:CKV65_RS00945
uniprot id: A0A239T980
names: Similarity
messages: Belongs to the Skp family.

158847:CKV65 RS06055
gene id: 158847:CKV65_RS06055
uniprot id: A0A239TTT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

158847:CKV65 RS07980
gene id: 158847:CKV65_RS07980
uniprot id: A0A239TXM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

158847:CKV65 RS01825
gene id: 158847:CKV65_RS01825
uniprot id: A0A239TEL9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

158847:CKV65 RS01765
gene id: 158847:CKV65_RS01765
uniprot id: A0A239TEH8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS07290
gene id: 158847:CKV65_RS07290
uniprot id: A0A239TVF9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

158847:CKV65 RS01220
gene id: 158847:CKV65_RS01220
uniprot id: A0A239TCV4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

158847:CKV65 RS01760
gene id: 158847:CKV65_RS01760
uniprot id: A0A239TDM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

158847:CKV65 RS00240
gene id: 158847:CKV65_RS00240
uniprot id: A0A239T7E3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

158847:CKV65 RS03625
gene id: 158847:CKV65_RS03625
uniprot id: A0A239TL71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

158847:CKV65 RS06260
gene id: 158847:CKV65_RS06260
uniprot id: A0A239TR54
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

158847:CKV65 RS06885
gene id: 158847:CKV65_RS06885
uniprot id: A0A239TTY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS07440
gene id: 158847:CKV65_RS07440
uniprot id: A0A239TZ35
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

158847:CKV65 RS07090
gene id: 158847:CKV65_RS07090
uniprot id: A0A239TU12
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

158847:CKV65 RS05345
gene id: 158847:CKV65_RS05345
uniprot id: A0A239TNE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

158847:CKV65 RS00665
gene id: 158847:CKV65_RS00665
uniprot id: A0A239TAS8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

158847:CKV65 RS07555
gene id: 158847:CKV65_RS07555
uniprot id: A0A239TY63
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

158847:CKV65 RS09685
gene id: 158847:CKV65_RS09685
uniprot id: A0A239U2Z9
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS09080
gene id: 158847:CKV65_RS09080
uniprot id: A0A239U3T5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

158847:CKV65 RS07760
gene id: 158847:CKV65_RS07760
uniprot id: A0A239TX14
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

158847:CKV65 RS09350
gene id: 158847:CKV65_RS09350
uniprot id: A0A239U314
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

158847:CKV65 RS02580
gene id: 158847:CKV65_RS02580
uniprot id: A0A239TEJ7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

158847:CKV65 RS02465
gene id: 158847:CKV65_RS02465
uniprot id: A0A239TE13
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

158847:CKV65 RS04565
gene id: 158847:CKV65_RS04565
uniprot id: A0A239TNP9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

158847:CKV65 RS04290
gene id: 158847:CKV65_RS04290
uniprot id: A0A239TND9
names: Similarity
messages: Belongs to the UPF0111 family.

158847:CKV65 RS09265
gene id: 158847:CKV65_RS09265
uniprot id: A0A239U493
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS10185
gene id: 158847:CKV65_RS10185
uniprot id: A0A239U4E9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS00685
gene id: 158847:CKV65_RS00685
uniprot id: A0A239TB50
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS06830
gene id: 158847:CKV65_RS06830
uniprot id: A0A239TWY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

158847:CKV65 RS08060
gene id: 158847:CKV65_RS08060
uniprot id: A0A239TY25
names: Similarity
messages: Belongs to the FBPase class 3 family.

158847:CKV65 RS01435
gene id: 158847:CKV65_RS01435
uniprot id: A0A239TBB3
names: Similarity
messages: Belongs to the UPF0102 family.

158847:CKV65 RS03360
gene id: 158847:CKV65_RS03360
uniprot id: A0A239TH53
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

158847:CKV65 RS02720
gene id: 158847:CKV65_RS02720
uniprot id: A0A239TF23
names: Similarity
messages: Belongs to the peptidase S66 family.

158847:CKV65 RS00425
gene id: 158847:CKV65_RS00425
uniprot id: A0A239T7V4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

158847:CKV65 RS04825
gene id: 158847:CKV65_RS04825
uniprot id: A0A239TQA3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

158847:CKV65 RS09420
gene id: 158847:CKV65_RS09420
uniprot id: A0A239U1P7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

158847:CKV65 RS03855
gene id: 158847:CKV65_RS03855
uniprot id: A0A239TIQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

158847:CKV65 RS03045
gene id: 158847:CKV65_RS03045
uniprot id: A0A239TH64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

158847:CKV65 RS06335
gene id: 158847:CKV65_RS06335
uniprot id: A0A239TS51
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

158847:CKV65 RS05690
gene id: 158847:CKV65_RS05690
uniprot id: A0A239TQJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

158847:CKV65 RS04510
gene id: 158847:CKV65_RS04510
uniprot id: A0A239TP58
names: Similarity
messages: Belongs to the UPF0237 family.

158847:CKV65 RS05355
gene id: 158847:CKV65_RS05355
uniprot id: A0A239TNF7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

158847:CKV65 RS00755
gene id: 158847:CKV65_RS00755
uniprot id: A0A239T8S1
names: Similarity
messages: Belongs to the UPF0174 family.

158847:CKV65 RS06190
gene id: 158847:CKV65_RS06190
uniprot id: A0A239TRQ6
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

158847:CKV65 RS02600
gene id: 158847:CKV65_RS02600
uniprot id: A0A239TEY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

158847:CKV65 RS02425
gene id: 158847:CKV65_RS02425
uniprot id: A0A239TGG3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

158847:CKV65 RS09280
gene id: 158847:CKV65_RS09280
uniprot id: A0A239U257
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

158847:CKV65 RS10545
gene id: 158847:CKV65_RS10545
uniprot id: A0A239U646
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

158847:CKV65 RS09835
gene id: 158847:CKV65_RS09835
uniprot id: A0A239U6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS06480
gene id: 158847:CKV65_RS06480
uniprot id: A0A239TS55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

158847:CKV65 RS08260
gene id: 158847:CKV65_RS08260
uniprot id: A0A239U197
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS03710
gene id: 158847:CKV65_RS03710
uniprot id: A0A239TIC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

158847:CKV65 RS02545
gene id: 158847:CKV65_RS02545
uniprot id: A0A239TEC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS06585
gene id: 158847:CKV65_RS06585
uniprot id: A0A239TTB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

158847:CKV65 RS01545
gene id: 158847:CKV65_RS01545
uniprot id: A0A239TC43
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

158847:CKV65 RS10600
gene id: 158847:CKV65_RS10600
uniprot id: A0A239U766
names: Similarity
messages: Belongs to the universal stress protein A family.

158847:CKV65 RS09570
gene id: 158847:CKV65_RS09570
uniprot id: A0A239U2S2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS03535
gene id: 158847:CKV65_RS03535
uniprot id: A0A239THR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

158847:CKV65 RS07740
gene id: 158847:CKV65_RS07740
uniprot id: A0A239TYQ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

158847:CKV65 RS08090
gene id: 158847:CKV65_RS08090
uniprot id: A0A239TY85
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS10965
gene id: 158847:CKV65_RS10965
uniprot id: A0A239U6U7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

158847:CKV65 RS10070
gene id: 158847:CKV65_RS10070
uniprot id: A0A239U3Z3
names: Similarity
messages: Belongs to the sigma-54 factor family.

158847:CKV65 RS02635
gene id: 158847:CKV65_RS02635
uniprot id: A0A239TGZ6
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS05710
gene id: 158847:CKV65_RS05710
uniprot id: A0A239TRD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

158847:CKV65 RS08550
gene id: 158847:CKV65_RS08550
uniprot id: A0A239U0Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

158847:CKV65 RS05390
gene id: 158847:CKV65_RS05390
uniprot id: A0A239TNU4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

158847:CKV65 RS05105
gene id: 158847:CKV65_RS05105
uniprot id: A0A239TPG3
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

158847:CKV65 RS01250
gene id: 158847:CKV65_RS01250
uniprot id: A0A239TCC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

158847:CKV65 RS02665
gene id: 158847:CKV65_RS02665
uniprot id: A0A239TF28
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

158847:CKV65 RS08940
gene id: 158847:CKV65_RS08940
uniprot id: A0A239U1B4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS04470
gene id: 158847:CKV65_RS04470
uniprot id: A0A239TMD9
names: Subcellular Location Annotation
messages: Cell membrane

158847:CKV65 RS03235
gene id: 158847:CKV65_RS03235
uniprot id: A0A239TGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

158847:CKV65 RS03995
gene id: 158847:CKV65_RS03995
uniprot id: A0A239TJR1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

158847:CKV65 RS03185
gene id: 158847:CKV65_RS03185
uniprot id: A0A239TJF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

158847:CKV65 RS04590
gene id: 158847:CKV65_RS04590
uniprot id: A0A239TKQ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS10015
gene id: 158847:CKV65_RS10015
uniprot id: A0A239U4B7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

158847:CKV65 RS10145
gene id: 158847:CKV65_RS10145
uniprot id: A0A239U7J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

158847:CKV65 RS08130
gene id: 158847:CKV65_RS08130
uniprot id: A0A239TXT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS05250
gene id: 158847:CKV65_RS05250
uniprot id: A0A239TN36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

158847:CKV65 RS01375
gene id: 158847:CKV65_RS01375
uniprot id: A0A239TB70
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS10380
gene id: 158847:CKV65_RS10380
uniprot id: A0A239U522
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS06735
gene id: 158847:CKV65_RS06735
uniprot id: A0A239TU75
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS01630
gene id: 158847:CKV65_RS01630
uniprot id: A0A239TBQ4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

158847:CKV65 RS08645
gene id: 158847:CKV65_RS08645
uniprot id: A0A239U0C7
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS10375
gene id: 158847:CKV65_RS10375
uniprot id: A0A239U5J2
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

158847:CKV65 RS07495
gene id: 158847:CKV65_RS07495
uniprot id: A0A239TXZ2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

158847:CKV65 RS02300
gene id: 158847:CKV65_RS02300
uniprot id: A0A239TDR6
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

158847:CKV65 RS04880
gene id: 158847:CKV65_RS04880
uniprot id: A0A239TM23
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

158847:CKV65 RS09690
gene id: 158847:CKV65_RS09690
uniprot id: A0A239U3I9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

158847:CKV65 RS02485
gene id: 158847:CKV65_RS02485
uniprot id: A0A239TFF3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

158847:CKV65 RS09945
gene id: 158847:CKV65_RS09945
uniprot id: A0A239U506
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

158847:CKV65 RS10660
gene id: 158847:CKV65_RS10660
uniprot id: A0A239U6A0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158847:CKV65 RS04600
gene id: 158847:CKV65_RS04600
uniprot id: A0A239TNV0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

158847:CKV65 RS05875
gene id: 158847:CKV65_RS05875
uniprot id: A0A239TQS2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

158847:CKV65 RS09390
gene id: 158847:CKV65_RS09390
uniprot id: A0A239U256
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

158847:CKV65 RS06625
gene id: 158847:CKV65_RS06625
uniprot id: A0A239TVS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

158847:CKV65 RS05720
gene id: 158847:CKV65_RS05720
uniprot id: A0A239TPI2
names: Similarity
messages: Belongs to the RpoE family.

158847:CKV65 RS02380
gene id: 158847:CKV65_RS02380
uniprot id: A0A239TDQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS08640
gene id: 158847:CKV65_RS08640
uniprot id: A0A239U338
names: Similarity
messages: Belongs to the UPF0111 family.

158847:CKV65 RS10675
gene id: 158847:CKV65_RS10675
uniprot id: A0A239U602
names: Similarity
messages: Belongs to the P(II) protein family.

158847:CKV65 RS01280
gene id: 158847:CKV65_RS01280
uniprot id: A0A239TD13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

158847:CKV65 RS06365
gene id: 158847:CKV65_RS06365
uniprot id: A0A239TS70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS05070
gene id: 158847:CKV65_RS05070
uniprot id: A0A239TMD0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

158847:CKV65 RS10525
gene id: 158847:CKV65_RS10525
uniprot id: A0A239U626
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

158847:CKV65 RS02375
gene id: 158847:CKV65_RS02375
uniprot id: A0A239TDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS06090
gene id: 158847:CKV65_RS06090
uniprot id: A0A239TT58
names: Similarity
messages: Belongs to the transglycosylase Slt family.

158847:CKV65 RS04580
gene id: 158847:CKV65_RS04580
uniprot id: A0A239TKY3
names: Similarity
messages: Belongs to the ycf81 family.

158847:CKV65 RS08870
gene id: 158847:CKV65_RS08870
uniprot id: A0A239U074
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS01670
gene id: 158847:CKV65_RS01670
uniprot id: A0A239TDD0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS02770
gene id: 158847:CKV65_RS02770
uniprot id: A0A239TFK1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

158847:CKV65 RS01345
gene id: 158847:CKV65_RS01345
uniprot id: A0A239TBL3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

158847:CKV65 RS04630
gene id: 158847:CKV65_RS04630
uniprot id: A0A239TL38
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

158847:CKV65 RS10475
gene id: 158847:CKV65_RS10475
uniprot id: A0A239U664
names: Similarity
messages: Belongs to the thioesterase PaaI family.

158847:CKV65 RS05860
gene id: 158847:CKV65_RS05860
uniprot id: A0A239TQ88
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

158847:CKV65 RS07295
gene id: 158847:CKV65_RS07295
uniprot id: A0A239TW82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

158847:CKV65 RS03205
gene id: 158847:CKV65_RS03205
uniprot id: A0A239TGK9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

158847:CKV65 RS01750
gene id: 158847:CKV65_RS01750
uniprot id: A0A239TCK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

158847:CKV65 RS07490
gene id: 158847:CKV65_RS07490
uniprot id: A0A239TVP3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

158847:CKV65 RS03685
gene id: 158847:CKV65_RS03685
uniprot id: A0A239TJ05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

158847:CKV65 RS01550
gene id: 158847:CKV65_RS01550
uniprot id: A0A239TC61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

158847:CKV65 RS04200
gene id: 158847:CKV65_RS04200
uniprot id: A0A921L7X0
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

158847:CKV65 RS01890
gene id: 158847:CKV65_RS01890
uniprot id: A0A239TCB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

158847:CKV65 RS04765
gene id: 158847:CKV65_RS04765
uniprot id: A0A239TLF6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

158847:CKV65 RS06865
gene id: 158847:CKV65_RS06865
uniprot id: A0A239TVT0
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS01260
gene id: 158847:CKV65_RS01260
uniprot id: A0A239TAI5
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

158847:CKV65 RS05530
gene id: 158847:CKV65_RS05530
uniprot id: A0A239TQ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

158847:CKV65 RS08795
gene id: 158847:CKV65_RS08795
uniprot id: A0A239U0X3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

158847:CKV65 RS06725
gene id: 158847:CKV65_RS06725
uniprot id: A0A239TVB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

158847:CKV65 RS01020
gene id: 158847:CKV65_RS01020
uniprot id: A0A239TBZ2
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

158847:CKV65 RS09630
gene id: 158847:CKV65_RS09630
uniprot id: A0A239U4I0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS09480
gene id: 158847:CKV65_RS09480
uniprot id: A0A239U5A9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

158847:CKV65 RS02510
gene id: 158847:CKV65_RS02510
uniprot id: A0A239TEC8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS10630
gene id: 158847:CKV65_RS10630
uniprot id: A0A239U8V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

158847:CKV65 RS01845
gene id: 158847:CKV65_RS01845
uniprot id: A0A239TEH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

158847:CKV65 RS06800
gene id: 158847:CKV65_RS06800
uniprot id: A0A239TUL5
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS09240
gene id: 158847:CKV65_RS09240
uniprot id: A0A239U393
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

158847:CKV65 RS07840
gene id: 158847:CKV65_RS07840
uniprot id: A0A239TXY6
names: Similarity
messages: Belongs to the universal stress protein A family.

158847:CKV65 RS06310
gene id: 158847:CKV65_RS06310
uniprot id: A0A239TS30
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

158847:CKV65 RS09885
gene id: 158847:CKV65_RS09885
uniprot id: A0A239U3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

158847:CKV65 RS09830
gene id: 158847:CKV65_RS09830
uniprot id: A0A239U3P9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

158847:CKV65 RS08615
gene id: 158847:CKV65_RS08615
uniprot id: A0A239U151
names: Subcellular Location Annotation
messages: Periplasm

158847:CKV65 RS10555
gene id: 158847:CKV65_RS10555
uniprot id: A0A239U6G0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

158847:CKV65 RS03225
gene id: 158847:CKV65_RS03225
uniprot id: A0A239TJQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS03810
gene id: 158847:CKV65_RS03810
uniprot id: A0A239TLR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

158847:CKV65 RS09195
gene id: 158847:CKV65_RS09195
uniprot id: A0A239U415
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

158847:CKV65 RS07165
gene id: 158847:CKV65_RS07165
uniprot id: A0A239TUX2
names: Similarity
messages: Belongs to the UPF0251 family.

158847:CKV65 RS03760
gene id: 158847:CKV65_RS03760
uniprot id: A0A239TID3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

158847:CKV65 RS00100
gene id: 158847:CKV65_RS00100
uniprot id: A0A239T705
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

158847:CKV65 RS07615
gene id: 158847:CKV65_RS07615
uniprot id: A0A239TWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

158847:CKV65 RS02280
gene id: 158847:CKV65_RS02280
uniprot id: A0A239TEU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

158847:CKV65 RS09170
gene id: 158847:CKV65_RS09170
uniprot id: A0A239U0Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

158847:CKV65 RS02745
gene id: 158847:CKV65_RS02745
uniprot id: A0A239THP8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

158847:CKV65 RS06030
gene id: 158847:CKV65_RS06030
uniprot id: A0A239TR17
names: Similarity
messages: Belongs to the LacAB/RpiB family.

158847:CKV65 RS06230
gene id: 158847:CKV65_RS06230
uniprot id: A0A239TTR6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

158847:CKV65 RS09385
gene id: 158847:CKV65_RS09385
uniprot id: A0A239U208
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS07170
gene id: 158847:CKV65_RS07170
uniprot id: A0A239TVP0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS04885
gene id: 158847:CKV65_RS04885
uniprot id: A0A239TMP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS07325
gene id: 158847:CKV65_RS07325
uniprot id: A0A239TVL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

158847:CKV65 RS02455
gene id: 158847:CKV65_RS02455
uniprot id: A0A239TDY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

158847:CKV65 RS03935
gene id: 158847:CKV65_RS03935
uniprot id: A0A239TJD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

158847:CKV65 RS02950
gene id: 158847:CKV65_RS02950
uniprot id: A0A239TGX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

158847:CKV65 RS06790
gene id: 158847:CKV65_RS06790
uniprot id: A0A239TTJ7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

158847:CKV65 RS08325
gene id: 158847:CKV65_RS08325
uniprot id: A0A239TYW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

158847:CKV65 RS05140
gene id: 158847:CKV65_RS05140
uniprot id: A0A239TNG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

158847:CKV65 RS05750
gene id: 158847:CKV65_RS05750
uniprot id: A0A239TPW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

158847:CKV65 RS02630
gene id: 158847:CKV65_RS02630
uniprot id: A0A239TG08
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

158847:CKV65 RS09020
gene id: 158847:CKV65_RS09020
uniprot id: A0A239U3N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS08970
gene id: 158847:CKV65_RS08970
uniprot id: A0A239U0K3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

158847:CKV65 RS01460
gene id: 158847:CKV65_RS01460
uniprot id: A0A239TBS7
names: Similarity
messages: Belongs to the GSP E family.

158847:CKV65 RS05270
gene id: 158847:CKV65_RS05270
uniprot id: A0A239TNF6
names: Similarity
messages: Belongs to the class-I fumarase family.

158847:CKV65 RS03425
gene id: 158847:CKV65_RS03425
uniprot id: A0A239TJU4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158847:CKV65 RS02060
gene id: 158847:CKV65_RS02060
uniprot id: A0A239TCR7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS01110
gene id: 158847:CKV65_RS01110
uniprot id: A0A239TCJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

158847:CKV65 RS02620
gene id: 158847:CKV65_RS02620
uniprot id: A0A239TGX6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

158847:CKV65 RS03965
gene id: 158847:CKV65_RS03965
uniprot id: A0A239TIR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

158847:CKV65 RS01140
gene id: 158847:CKV65_RS01140
uniprot id: A0A239TBW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

158847:CKV65 RS09100
gene id: 158847:CKV65_RS09100
uniprot id: A0A239U0U4
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

158847:CKV65 RS02340
gene id: 158847:CKV65_RS02340
uniprot id: A0A239TDL2
names: Similarity
messages: Belongs to the peptidase S49 family.

158847:CKV65 RS05225
gene id: 158847:CKV65_RS05225
uniprot id: A0A239TN05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

158847:CKV65 RS07280
gene id: 158847:CKV65_RS07280
uniprot id: A0A239TUV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

158847:CKV65 RS09790
gene id: 158847:CKV65_RS09790
uniprot id: A0A239U3K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

158847:CKV65 RS03600
gene id: 158847:CKV65_RS03600
uniprot id: A0A239THW8
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

158847:CKV65 RS03725
gene id: 158847:CKV65_RS03725
uniprot id: A0A239TI14
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

158847:CKV65 RS05715
gene id: 158847:CKV65_RS05715
uniprot id: A0A239TSZ5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS02085
gene id: 158847:CKV65_RS02085
uniprot id: A0A239TF47
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS03815
gene id: 158847:CKV65_RS03815
uniprot id: A0A239TJ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

158847:CKV65 RS00220
gene id: 158847:CKV65_RS00220
uniprot id: A0A239T7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

158847:CKV65 RS05740
gene id: 158847:CKV65_RS05740
uniprot id: A0A239TPJ6
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

158847:CKV65 RS06170
gene id: 158847:CKV65_RS06170
uniprot id: A0A239TRK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

158847:CKV65 RS04560
gene id: 158847:CKV65_RS04560
uniprot id: A0A239TML3
names: Caution
names: Function
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS08200
gene id: 158847:CKV65_RS08200
uniprot id: A0A239TYB2
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS10055
gene id: 158847:CKV65_RS10055
uniprot id: A0A239U4H2
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

158847:CKV65 RS02170
gene id: 158847:CKV65_RS02170
uniprot id: A0A239TD23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

158847:CKV65 RS09800
gene id: 158847:CKV65_RS09800
uniprot id: A0A239U541
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

158847:CKV65 RS04060
gene id: 158847:CKV65_RS04060
uniprot id: A0A239TJ25
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

158847:CKV65 RS06555
gene id: 158847:CKV65_RS06555
uniprot id: A0A239TSM5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

158847:CKV65 RS06450
gene id: 158847:CKV65_RS06450
uniprot id: A0A239TRP4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

158847:CKV65 RS04080
gene id: 158847:CKV65_RS04080
uniprot id: A0A239TM49
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

158847:CKV65 RS01840
gene id: 158847:CKV65_RS01840
uniprot id: A0A239TC67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

158847:CKV65 RS05125
gene id: 158847:CKV65_RS05125
uniprot id: A0A239TNJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158847:CKV65 RS02045
gene id: 158847:CKV65_RS02045
uniprot id: A0A239TD31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS07805
gene id: 158847:CKV65_RS07805
uniprot id: A0A239TXU3
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS04755
gene id: 158847:CKV65_RS04755
uniprot id: A0A239TNB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

158847:CKV65 RS09115
gene id: 158847:CKV65_RS09115
uniprot id: A0A239U1Q0
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

158847:CKV65 RS08935
gene id: 158847:CKV65_RS08935
uniprot id: A0A239U2J3
names: Similarity
messages: Belongs to the IMPACT family.

158847:CKV65 RS01660
gene id: 158847:CKV65_RS01660
uniprot id: A0A239TBR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

158847:CKV65 RS01305
gene id: 158847:CKV65_RS01305
uniprot id: A0A239TAV6
names: Similarity
messages: Belongs to the leucine-binding protein family.

158847:CKV65 RS03030
gene id: 158847:CKV65_RS03030
uniprot id: A0A239TFZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

158847:CKV65 RS08805
gene id: 158847:CKV65_RS08805
uniprot id: A0A239U0H3
names: Similarity
messages: Belongs to the citrate synthase family.

158847:CKV65 RS07600
gene id: 158847:CKV65_RS07600
uniprot id: A0A239TX16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

158847:CKV65 RS02250
gene id: 158847:CKV65_RS02250
uniprot id: A0A239TDA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS03820
gene id: 158847:CKV65_RS03820
uniprot id: A0A239TIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

158847:CKV65 RS05955
gene id: 158847:CKV65_RS05955
uniprot id: A0A239TQB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

158847:CKV65 RS02995
gene id: 158847:CKV65_RS02995
uniprot id: A0A239TG91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS01350
gene id: 158847:CKV65_RS01350
uniprot id: A0A239TBS6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS06165
gene id: 158847:CKV65_RS06165
uniprot id: A0A239TRL7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

158847:CKV65 RS04785
gene id: 158847:CKV65_RS04785
uniprot id: A0A239TLR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

158847:CKV65 RS08525
gene id: 158847:CKV65_RS08525
uniprot id: A0A239TZV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

158847:CKV65 RS03100
gene id: 158847:CKV65_RS03100
uniprot id: A0A239TGR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

158847:CKV65 RS03005
gene id: 158847:CKV65_RS03005
uniprot id: A0A239TGA3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS00550
gene id: 158847:CKV65_RS00550
uniprot id: A0A239T8K0
names: Similarity
messages: Belongs to the thioredoxin family.

158847:CKV65 RS07870
gene id: 158847:CKV65_RS07870
uniprot id: A0A239U031
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

158847:CKV65 RS10635
gene id: 158847:CKV65_RS10635
uniprot id: A0A239U6F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

158847:CKV65 RS00500
gene id: 158847:CKV65_RS00500
uniprot id: A0A239T800
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

158847:CKV65 RS03700
gene id: 158847:CKV65_RS03700
uniprot id: A0A239TIB1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

158847:CKV65 RS08315
gene id: 158847:CKV65_RS08315
uniprot id: A0A239TZW5
names: Similarity
messages: Belongs to the glycosyl hydrolase.

158847:CKV65 RS07350
gene id: 158847:CKV65_RS07350
uniprot id: A0A239TW70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

158847:CKV65 RS09375
gene id: 158847:CKV65_RS09375
uniprot id: A0A239U324
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

158847:CKV65 RS01555
gene id: 158847:CKV65_RS01555
uniprot id: A0A239TBI8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

158847:CKV65 RS08505
gene id: 158847:CKV65_RS08505
uniprot id: A0A239TZT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

158847:CKV65 RS04000
gene id: 158847:CKV65_RS04000
uniprot id: A0A239TKQ9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

158847:CKV65 RS02795
gene id: 158847:CKV65_RS02795
uniprot id: A0A239TGH3
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

158847:CKV65 RS04645
gene id: 158847:CKV65_RS04645
uniprot id: A0A239TL61
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

158847:CKV65 RS03075
gene id: 158847:CKV65_RS03075
uniprot id: A0A239TGA7
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS02750
gene id: 158847:CKV65_RS02750
uniprot id: A0A239TFI2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

158847:CKV65 RS04150
gene id: 158847:CKV65_RS04150
uniprot id: A0A239TJN0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

158847:CKV65 RS00160
gene id: 158847:CKV65_RS00160
uniprot id: A0A239T779
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

158847:CKV65 RS10065
gene id: 158847:CKV65_RS10065
uniprot id: A0A239U4R4
names: Similarity
messages: Belongs to the hexokinase family.

158847:CKV65 RS00350
gene id: 158847:CKV65_RS00350
uniprot id: A0A239T9X6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

158847:CKV65 RS01985
gene id: 158847:CKV65_RS01985
uniprot id: A0A239TE69
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

158847:CKV65 RS01880
gene id: 158847:CKV65_RS01880
uniprot id: A0A239TCW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

158847:CKV65 RS01045
gene id: 158847:CKV65_RS01045
uniprot id: A0A239TBR3
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS09190
gene id: 158847:CKV65_RS09190
uniprot id: A0A239U2I7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

158847:CKV65 RS09000
gene id: 158847:CKV65_RS09000
uniprot id: A0A239U0V6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

158847:CKV65 RS05945
gene id: 158847:CKV65_RS05945
uniprot id: A0A239TTK9
names: Similarity
messages: Belongs to the EamA transporter family.

158847:CKV65 RS00710
gene id: 158847:CKV65_RS00710
uniprot id: A0A239TAK6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

158847:CKV65 RS10550
gene id: 158847:CKV65_RS10550
uniprot id: A0A239U645
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

158847:CKV65 RS00195
gene id: 158847:CKV65_RS00195
uniprot id: A0A239T7B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

158847:CKV65 RS08880
gene id: 158847:CKV65_RS08880
uniprot id: A0A239U134
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS08670
gene id: 158847:CKV65_RS08670
uniprot id: A0A239U2W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

158847:CKV65 RS02765
gene id: 158847:CKV65_RS02765
uniprot id: A0A239TF36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

158847:CKV65 RS07175
gene id: 158847:CKV65_RS07175
uniprot id: A0A239TY43
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS06325
gene id: 158847:CKV65_RS06325
uniprot id: A0A239TT74
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

158847:CKV65 RS08605
gene id: 158847:CKV65_RS08605
uniprot id: A0A239U141
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

158847:CKV65 RS05075
gene id: 158847:CKV65_RS05075
uniprot id: A0A239TNF1
names: Similarity
messages: Belongs to the UPF0735 family.

158847:CKV65 RS03390
gene id: 158847:CKV65_RS03390
uniprot id: A0A239TIL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

158847:CKV65 RS07730
gene id: 158847:CKV65_RS07730
uniprot id: A0A239TYN0
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

158847:CKV65 RS05840
gene id: 158847:CKV65_RS05840
uniprot id: A0A239TSJ8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

158847:CKV65 RS09400
gene id: 158847:CKV65_RS09400
uniprot id: A0A239U354
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS02805
gene id: 158847:CKV65_RS02805
uniprot id: A0A239TGI3
names: Similarity
messages: Belongs to the YicC/YloC family.

158847:CKV65 RS09305
gene id: 158847:CKV65_RS09305
uniprot id: A0A239U3F9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS01475
gene id: 158847:CKV65_RS01475
uniprot id: A0A239TDN8
names: Similarity
messages: Belongs to the peptidase A24 family.

158847:CKV65 RS00695
gene id: 158847:CKV65_RS00695
uniprot id: A0A239T8M5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

158847:CKV65 RS07315
gene id: 158847:CKV65_RS07315
uniprot id: A0A239TWB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

158847:CKV65 RS03060
gene id: 158847:CKV65_RS03060
uniprot id: A0A239TGG7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

158847:CKV65 RS06610
gene id: 158847:CKV65_RS06610
uniprot id: A0A239TVQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

158847:CKV65 RS05210
gene id: 158847:CKV65_RS05210
uniprot id: A0A239TN90
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

158847:CKV65 RS05415
gene id: 158847:CKV65_RS05415
uniprot id: A0A239TNE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

158847:CKV65 RS05505
gene id: 158847:CKV65_RS05505
uniprot id: A0A239TPW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

158847:CKV65 RS09810
gene id: 158847:CKV65_RS09810
uniprot id: A0A239U552
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

158847:CKV65 RS07340
gene id: 158847:CKV65_RS07340
uniprot id: A0A239TVM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

158847:CKV65 RS04285
gene id: 158847:CKV65_RS04285
uniprot id: A0A239TK13
names: Similarity
messages: Belongs to the threonine synthase family.

158847:CKV65 RS01205
gene id: 158847:CKV65_RS01205
uniprot id: A0A239TAV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

158847:CKV65 RS02740
gene id: 158847:CKV65_RS02740
uniprot id: A0A239TF43
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

158847:CKV65 RS04620
gene id: 158847:CKV65_RS04620
uniprot id: A0A239TPI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS00975
gene id: 158847:CKV65_RS00975
uniprot id: A0A239T9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

158847:CKV65 RS10620
gene id: 158847:CKV65_RS10620
uniprot id: A0A239U940
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

158847:CKV65 RS03380
gene id: 158847:CKV65_RS03380
uniprot id: A0A239TIK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

158847:CKV65 RS03895
gene id: 158847:CKV65_RS03895
uniprot id: A0A239TKC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

158847:CKV65 RS06390
gene id: 158847:CKV65_RS06390
uniprot id: A0A239TRI1
names: Similarity
messages: Belongs to the asp23 family.

158847:CKV65 RS04320
gene id: 158847:CKV65_RS04320
uniprot id: A0A239TKQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

158847:CKV65 RS05885
gene id: 158847:CKV65_RS05885
uniprot id: A0A239TSQ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

158847:CKV65 RS08100
gene id: 158847:CKV65_RS08100
uniprot id: A0A239TYR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

158847:CKV65 RS06080
gene id: 158847:CKV65_RS06080
uniprot id: A0A239TQS7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

158847:CKV65 RS02295
gene id: 158847:CKV65_RS02295
uniprot id: A0A239TDU9
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

158847:CKV65 RS06010
gene id: 158847:CKV65_RS06010
uniprot id: A0A239TSX9
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS07260
gene id: 158847:CKV65_RS07260
uniprot id: A0A239TVT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

158847:CKV65 RS08245
gene id: 158847:CKV65_RS08245
uniprot id: A0A239U0B2
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

158847:CKV65 RS06980
gene id: 158847:CKV65_RS06980
uniprot id: A0A239TVC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

158847:CKV65 RS03795
gene id: 158847:CKV65_RS03795
uniprot id: A0A239TIG5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS10050
gene id: 158847:CKV65_RS10050
uniprot id: A0A239U4F8
names: Similarity
messages: Belongs to the peptidase S24 family.

158847:CKV65 RS07800
gene id: 158847:CKV65_RS07800
uniprot id: A0A239TX88
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS07690
gene id: 158847:CKV65_RS07690
uniprot id: A0A239TWW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

158847:CKV65 RS05065
gene id: 158847:CKV65_RS05065
uniprot id: A0A239TNE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

158847:CKV65 RS05260
gene id: 158847:CKV65_RS05260
uniprot id: A0A239TQ02
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

158847:CKV65 RS07285
gene id: 158847:CKV65_RS07285
uniprot id: A0A239TWI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

158847:CKV65 RS07910
gene id: 158847:CKV65_RS07910
uniprot id: A0A239U073
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

158847:CKV65 RS06420
gene id: 158847:CKV65_RS06420
uniprot id: A0A239TSD7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

158847:CKV65 RS05850
gene id: 158847:CKV65_RS05850
uniprot id: A0A239TQ74
names: Similarity
messages: Belongs to the Ahb/Nir family.

158847:CKV65 RS10490
gene id: 158847:CKV65_RS10490
uniprot id: A0A239U6S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

158847:CKV65 RS02640
gene id: 158847:CKV65_RS02640
uniprot id: A0A239TF30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

158847:CKV65 RS04895
gene id: 158847:CKV65_RS04895
uniprot id: A0A239TMQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS07215
gene id: 158847:CKV65_RS07215
uniprot id: A0A239TW75
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

158847:CKV65 RS07845
gene id: 158847:CKV65_RS07845
uniprot id: A0A239TZ24
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS07560
gene id: 158847:CKV65_RS07560
uniprot id: A0A239TX60
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

158847:CKV65 RS01735
gene id: 158847:CKV65_RS01735
uniprot id: A0A239TCK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

158847:CKV65 RS01335
gene id: 158847:CKV65_RS01335
uniprot id: A0A239TB54
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

158847:CKV65 RS05430
gene id: 158847:CKV65_RS05430
uniprot id: A0A239TPF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

158847:CKV65 RS06850
gene id: 158847:CKV65_RS06850
uniprot id: A0A239TVR0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS00585
gene id: 158847:CKV65_RS00585
uniprot id: A0A239T8X6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

158847:CKV65 RS06520
gene id: 158847:CKV65_RS06520
uniprot id: A0A239TSM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

158847:CKV65 RS01780
gene id: 158847:CKV65_RS01780
uniprot id: A0A239TC49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

158847:CKV65 RS05010
gene id: 158847:CKV65_RS05010
uniprot id: A0A239TP52
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

158847:CKV65 RS00595
gene id: 158847:CKV65_RS00595
uniprot id: A0A239T8Q7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

158847:CKV65 RS02645
gene id: 158847:CKV65_RS02645
uniprot id: A0A239TER5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS03950
gene id: 158847:CKV65_RS03950
uniprot id: A0A239TLQ0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

158847:CKV65 RS06045
gene id: 158847:CKV65_RS06045
uniprot id: A0A239TPZ9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

158847:CKV65 RS10215
gene id: 158847:CKV65_RS10215
uniprot id: A0A239U7S3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

158847:CKV65 RS07565
gene id: 158847:CKV65_RS07565
uniprot id: A0A239TWY3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

158847:CKV65 RS08610
gene id: 158847:CKV65_RS08610
uniprot id: A0A239U0J2
names: Subunit
messages: Homotetramer.

158847:CKV65 RS09105
gene id: 158847:CKV65_RS09105
uniprot id: A0A239U1P1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS06025
gene id: 158847:CKV65_RS06025
uniprot id: A0A239TQE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS04745
gene id: 158847:CKV65_RS04745
uniprot id: A0A239TLI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS08015
gene id: 158847:CKV65_RS08015
uniprot id: A0A239U0I7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS02290
gene id: 158847:CKV65_RS02290
uniprot id: A0A239TDE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

158847:CKV65 RS02660
gene id: 158847:CKV65_RS02660
uniprot id: A0A239TEU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

158847:CKV65 RS05735
gene id: 158847:CKV65_RS05735
uniprot id: A0A239TT16
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS02690
gene id: 158847:CKV65_RS02690
uniprot id: A0A239TH57
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

158847:CKV65 RS07335
gene id: 158847:CKV65_RS07335
uniprot id: A0A239TYA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

158847:CKV65 RS05420
gene id: 158847:CKV65_RS05420
uniprot id: A0A239TNX7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

158847:CKV65 RS07180
gene id: 158847:CKV65_RS07180
uniprot id: A0A239TUZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

158847:CKV65 RS07220
gene id: 158847:CKV65_RS07220
uniprot id: A0A239TV62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

158847:CKV65 RS05920
gene id: 158847:CKV65_RS05920
uniprot id: A0A239TQ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

158847:CKV65 RS06750
gene id: 158847:CKV65_RS06750
uniprot id: A0A239TTG0
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

158847:CKV65 RS05410
gene id: 158847:CKV65_RS05410
uniprot id: A0A239TQE9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

158847:CKV65 RS02710
gene id: 158847:CKV65_RS02710
uniprot id: A0A239TF73
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

158847:CKV65 RS10730
gene id: 158847:CKV65_RS10730
uniprot id: A0A239U6R3
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS02655
gene id: 158847:CKV65_RS02655
uniprot id: A0A239TEV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

158847:CKV65 RS04180
gene id: 158847:CKV65_RS04180
uniprot id: A0A239TJG3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

158847:CKV65 RS05510
gene id: 158847:CKV65_RS05510
uniprot id: A0A239TSB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS08205
gene id: 158847:CKV65_RS08205
uniprot id: A0A239TYJ4
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS02185
gene id: 158847:CKV65_RS02185
uniprot id: A0A239TDI6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

158847:CKV65 RS00575
gene id: 158847:CKV65_RS00575
uniprot id: A0A239T8Y0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

158847:CKV65 RS02810
gene id: 158847:CKV65_RS02810
uniprot id: A0A239TF90
names: Similarity
messages: Belongs to the RemA family.

158847:CKV65 RS03375
gene id: 158847:CKV65_RS03375
uniprot id: A0A239TKA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

158847:CKV65 RS04570
gene id: 158847:CKV65_RS04570
uniprot id: A0A239TKX2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

158847:CKV65 RS08705
gene id: 158847:CKV65_RS08705
uniprot id: A0A239U2Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS03200
gene id: 158847:CKV65_RS03200
uniprot id: A0A239THX9
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

158847:CKV65 RS09605
gene id: 158847:CKV65_RS09605
uniprot id: A0A239U2T0
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

158847:CKV65 RS06785
gene id: 158847:CKV65_RS06785
uniprot id: A0A239TT15
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

158847:CKV65 RS07810
gene id: 158847:CKV65_RS07810
uniprot id: A0A239TXA1
names: Subcellular Location Annotation
messages: Cytoplasm

158847:CKV65 RS04675
gene id: 158847:CKV65_RS04675
uniprot id: A0A239TLC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

158847:CKV65 RS07925
gene id: 158847:CKV65_RS07925
uniprot id: A0A239TZB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

158847:CKV65 RS00560
gene id: 158847:CKV65_RS00560
uniprot id: A0A239T8K8
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

158847:CKV65 RS00675
gene id: 158847:CKV65_RS00675
uniprot id: A0A239TB39
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS09135
gene id: 158847:CKV65_RS09135
uniprot id: A0A239U0X4
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

158847:CKV65 RS04875
gene id: 158847:CKV65_RS04875
uniprot id: A0A239TM64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

158847:CKV65 RS04960
gene id: 158847:CKV65_RS04960
uniprot id: A0A239TQ27
names: Similarity
messages: Belongs to the peptidase C40 family.

158847:CKV65 RS04705
gene id: 158847:CKV65_RS04705
uniprot id: A0A239TMF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS00670
gene id: 158847:CKV65_RS00670
uniprot id: A0A239TAG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

158847:CKV65 RS09070
gene id: 158847:CKV65_RS09070
uniprot id: A0A239U0T6
names: Similarity
messages: Belongs to the peptidase A31 family.

158847:CKV65 RS08720
gene id: 158847:CKV65_RS08720
uniprot id: A0A239U3C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

158847:CKV65 RS03015
gene id: 158847:CKV65_RS03015
uniprot id: A0A239TIQ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158847:CKV65 RS01225
gene id: 158847:CKV65_RS01225
uniprot id: A0A239TB08
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

158847:CKV65 RS08005
gene id: 158847:CKV65_RS08005
uniprot id: A0A239U0T4
names: Subcellular Location Annotation
messages: Membrane

158847:CKV65 RS02825
gene id: 158847:CKV65_RS02825
uniprot id: A0A239TI27
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS07865
gene id: 158847:CKV65_RS07865
uniprot id: A0A239TYI0
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158847:CKV65 RS01215
gene id: 158847:CKV65_RS01215
uniprot id: A0A239TAC6
names: Similarity
messages: Belongs to the UbiD family.

158847:CKV65 RS02305
gene id: 158847:CKV65_RS02305
uniprot id: A0A239TDG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

158847:CKV65 RS01005
gene id: 158847:CKV65_RS01005
uniprot id: A0A239TBN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

158847:CKV65 RS09275
gene id: 158847:CKV65_RS09275
uniprot id: A0A378NNG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

158847:CKV65 RS03495
gene id: 158847:CKV65_RS03495
uniprot id: A0A239TJ22
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

158847:CKV65 RS03040
gene id: 158847:CKV65_RS03040
uniprot id: A0A239TIT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

158847:CKV65 RS05200
gene id: 158847:CKV65_RS05200
uniprot id: A0A239TN74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

158847:CKV65 RS09055
gene id: 158847:CKV65_RS09055
uniprot id: A0A239U1L2
names: Similarity
messages: Belongs to the HypD family.

158847:CKV65 RS02780
gene id: 158847:CKV65_RS02780
uniprot id: A0A239TF59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

158847:CKV65 RS06410
gene id: 158847:CKV65_RS06410
uniprot id: A0A239TR37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

158847:CKV65 RS07300
gene id: 158847:CKV65_RS07300
uniprot id: A0A239TUY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

158847:CKV65 RS07365
gene id: 158847:CKV65_RS07365
uniprot id: A0A239TWI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

158847:CKV65 RS09380
gene id: 158847:CKV65_RS09380
uniprot id: A0A239U2E2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

158847:CKV65 RS02155
gene id: 158847:CKV65_RS02155
uniprot id: A0A239TCZ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

158847:CKV65 RS01520
gene id: 158847:CKV65_RS01520
uniprot id: A0A239TDV5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

158847:CKV65 RS01445
gene id: 158847:CKV65_RS01445
uniprot id: A0A239TBC1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

158847:CKV65 RS01915
gene id: 158847:CKV65_RS01915
uniprot id: A0A239TCZ5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.