158190:SPIGRAPES RS06250
gene id: 158190:SPIGRAPES_RS06250
uniprot id: G8QTA5
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

158190:SPIGRAPES RS03515
gene id: 158190:SPIGRAPES_RS03515
uniprot id: G8QYI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS14970
gene id: 158190:SPIGRAPES_RS14970
uniprot id: G8QYB3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

158190:SPIGRAPES RS03535
gene id: 158190:SPIGRAPES_RS03535
uniprot id: G8QYJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS09230
gene id: 158190:SPIGRAPES_RS09230
uniprot id: G8QY87
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10720
gene id: 158190:SPIGRAPES_RS10720
uniprot id: G8QRK5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

158190:SPIGRAPES RS03530
gene id: 158190:SPIGRAPES_RS03530
uniprot id: G8QYJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS14830
gene id: 158190:SPIGRAPES_RS14830
uniprot id: G8QXT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

158190:SPIGRAPES RS05735
gene id: 158190:SPIGRAPES_RS05735
uniprot id: G8QSL4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

158190:SPIGRAPES RS01370
gene id: 158190:SPIGRAPES_RS01370
uniprot id: G8QUW1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

158190:SPIGRAPES RS08385
gene id: 158190:SPIGRAPES_RS08385
uniprot id: G8QWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS13650
gene id: 158190:SPIGRAPES_RS13650
uniprot id: G8QVX1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

158190:SPIGRAPES RS14725
gene id: 158190:SPIGRAPES_RS14725
uniprot id: G8QXR7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

158190:SPIGRAPES RS05095
gene id: 158190:SPIGRAPES_RS05095
uniprot id: G8QRR8
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

158190:SPIGRAPES RS00600
gene id: 158190:SPIGRAPES_RS00600
uniprot id: G8QTM2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

158190:SPIGRAPES RS10655
gene id: 158190:SPIGRAPES_RS10655
uniprot id: G8QRJ2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

158190:SPIGRAPES RS06300
gene id: 158190:SPIGRAPES_RS06300
uniprot id: G8QTB4
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS02960
gene id: 158190:SPIGRAPES_RS02960
uniprot id: G8QXE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

158190:SPIGRAPES RS05895
gene id: 158190:SPIGRAPES_RS05895
uniprot id: G8QSP5
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS09735
gene id: 158190:SPIGRAPES_RS09735
uniprot id: G8QQ99
names: Similarity
messages: Belongs to the thymidine kinase family.

158190:SPIGRAPES RS14290
gene id: 158190:SPIGRAPES_RS14290
uniprot id: G8QX40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

158190:SPIGRAPES RS05840
gene id: 158190:SPIGRAPES_RS05840
uniprot id: G8QSN4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

158190:SPIGRAPES RS14445
gene id: 158190:SPIGRAPES_RS14445
uniprot id: G8QX70
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS13315
gene id: 158190:SPIGRAPES_RS13315
uniprot id: G8QVB6
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15255
gene id: 158190:SPIGRAPES_RS15255
uniprot id: G8QYG7
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15960
gene id: 158190:SPIGRAPES_RS15960
uniprot id: G8QQM4
names: Similarity
messages: Belongs to the catalase family.

158190:SPIGRAPES RS01760
gene id: 158190:SPIGRAPES_RS01760
uniprot id: G8QVI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

158190:SPIGRAPES RS15155
gene id: 158190:SPIGRAPES_RS15155
uniprot id: G8QYE8
names: Similarity
messages: Belongs to the peptidase S1C family.

158190:SPIGRAPES RS02315
gene id: 158190:SPIGRAPES_RS02315
uniprot id: G8QW79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

158190:SPIGRAPES RS01500
gene id: 158190:SPIGRAPES_RS01500
uniprot id: G8QUY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

158190:SPIGRAPES RS00610
gene id: 158190:SPIGRAPES_RS00610
uniprot id: G8QTM4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

158190:SPIGRAPES RS00540
gene id: 158190:SPIGRAPES_RS00540
uniprot id: G8QTK9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

158190:SPIGRAPES RS11325
gene id: 158190:SPIGRAPES_RS11325
uniprot id: G8QSC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS08245
gene id: 158190:SPIGRAPES_RS08245
uniprot id: G8QWV7
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

158190:SPIGRAPES RS05405
gene id: 158190:SPIGRAPES_RS05405
uniprot id: G8QS52
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS05950
gene id: 158190:SPIGRAPES_RS05950
uniprot id: G8QSQ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

158190:SPIGRAPES RS04575
gene id: 158190:SPIGRAPES_RS04575
uniprot id: G8QR98
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

158190:SPIGRAPES RS04030
gene id: 158190:SPIGRAPES_RS04030
uniprot id: G8QQ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS01100
gene id: 158190:SPIGRAPES_RS01100
uniprot id: G8QUB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS07105
gene id: 158190:SPIGRAPES_RS07105
uniprot id: G8QV06
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS01735
gene id: 158190:SPIGRAPES_RS01735
uniprot id: G8QVH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

158190:SPIGRAPES RS10435
gene id: 158190:SPIGRAPES_RS10435
uniprot id: G8QR33
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS01215
gene id: 158190:SPIGRAPES_RS01215
uniprot id: G8QUD8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

158190:SPIGRAPES RS10155
gene id: 158190:SPIGRAPES_RS10155
uniprot id: G8QQY0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

158190:SPIGRAPES RS07210
gene id: 158190:SPIGRAPES_RS07210
uniprot id: G8QV27
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

158190:SPIGRAPES RS04145
gene id: 158190:SPIGRAPES_RS04145
uniprot id: G8QQ88
names: Similarity
messages: Belongs to the glutathione peroxidase family.

158190:SPIGRAPES RS15240
gene id: 158190:SPIGRAPES_RS15240
uniprot id: G8QYG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

158190:SPIGRAPES RS09365
gene id: 158190:SPIGRAPES_RS09365
uniprot id: G8QYQ2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

158190:SPIGRAPES RS03640
gene id: 158190:SPIGRAPES_RS03640
uniprot id: G8QYL0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

158190:SPIGRAPES RS02335
gene id: 158190:SPIGRAPES_RS02335
uniprot id: G8QWN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

158190:SPIGRAPES RS02265
gene id: 158190:SPIGRAPES_RS02265
uniprot id: G8QW69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

158190:SPIGRAPES RS00760
gene id: 158190:SPIGRAPES_RS00760
uniprot id: G8QTQ4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

158190:SPIGRAPES RS11620
gene id: 158190:SPIGRAPES_RS11620
uniprot id: G8QSS3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

158190:SPIGRAPES RS03660
gene id: 158190:SPIGRAPES_RS03660
uniprot id: G8QYL4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

158190:SPIGRAPES RS09065
gene id: 158190:SPIGRAPES_RS09065
uniprot id: G8QY54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS09790
gene id: 158190:SPIGRAPES_RS09790
uniprot id: G8QQB0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

158190:SPIGRAPES RS08875
gene id: 158190:SPIGRAPES_RS08875
uniprot id: G8QXL9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

158190:SPIGRAPES RS04355
gene id: 158190:SPIGRAPES_RS04355
uniprot id: G8QQS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS04095
gene id: 158190:SPIGRAPES_RS04095
uniprot id: G8QQ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS02395
gene id: 158190:SPIGRAPES_RS02395
uniprot id: G8QWP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS01585
gene id: 158190:SPIGRAPES_RS01585
uniprot id: G8QVE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS09215
gene id: 158190:SPIGRAPES_RS09215
uniprot id: G8QY84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

158190:SPIGRAPES RS10790
gene id: 158190:SPIGRAPES_RS10790
uniprot id: G8QRM0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

158190:SPIGRAPES RS03665
gene id: 158190:SPIGRAPES_RS03665
uniprot id: G8QYL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

158190:SPIGRAPES RS04730
gene id: 158190:SPIGRAPES_RS04730
uniprot id: G8QRC9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

158190:SPIGRAPES RS06380
gene id: 158190:SPIGRAPES_RS06380
uniprot id: G8QTD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS08950
gene id: 158190:SPIGRAPES_RS08950
uniprot id: G8QXN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS04105
gene id: 158190:SPIGRAPES_RS04105
uniprot id: G8QQ80
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

158190:SPIGRAPES RS14705
gene id: 158190:SPIGRAPES_RS14705
uniprot id: G8QXR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

158190:SPIGRAPES RS02930
gene id: 158190:SPIGRAPES_RS02930
uniprot id: G8QXD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

158190:SPIGRAPES RS12425
gene id: 158190:SPIGRAPES_RS12425
uniprot id: G8QU07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

158190:SPIGRAPES RS10250
gene id: 158190:SPIGRAPES_RS10250
uniprot id: G8QQZ6
names: Similarity
messages: Belongs to the peptidase S16 family.

158190:SPIGRAPES RS11120
gene id: 158190:SPIGRAPES_RS11120
uniprot id: G8QS10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

158190:SPIGRAPES RS13570
gene id: 158190:SPIGRAPES_RS13570
uniprot id: G8QVV5
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS02420
gene id: 158190:SPIGRAPES_RS02420
uniprot id: G8QWP9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

158190:SPIGRAPES RS16005
gene id: 158190:SPIGRAPES_RS16005
uniprot id: G8QQN3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

158190:SPIGRAPES RS01040
gene id: 158190:SPIGRAPES_RS01040
uniprot id: G8QUA5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

158190:SPIGRAPES RS07575
gene id: 158190:SPIGRAPES_RS07575
uniprot id: G8QVP3
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS05945
gene id: 158190:SPIGRAPES_RS05945
uniprot id: G8QSQ5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

158190:SPIGRAPES RS08605
gene id: 158190:SPIGRAPES_RS08605
uniprot id: G8QXG6
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS02490
gene id: 158190:SPIGRAPES_RS02490
uniprot id: G8QWR4
names: Subcellular Location Annotation
messages: Nucleus

158190:SPIGRAPES RS03950
gene id: 158190:SPIGRAPES_RS03950
uniprot id: G8QQ50
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

158190:SPIGRAPES RS04045
gene id: 158190:SPIGRAPES_RS04045
uniprot id: G8QQ68
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS06445
gene id: 158190:SPIGRAPES_RS06445
uniprot id: G8QTT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

158190:SPIGRAPES RS10815
gene id: 158190:SPIGRAPES_RS10815
uniprot id: G8QRM5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

158190:SPIGRAPES RS10670
gene id: 158190:SPIGRAPES_RS10670
uniprot id: G8QRJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

158190:SPIGRAPES RS01580
gene id: 158190:SPIGRAPES_RS01580
uniprot id: G8QV03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS09180
gene id: 158190:SPIGRAPES_RS09180
uniprot id: G8QY77
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS12760
gene id: 158190:SPIGRAPES_RS12760
uniprot id: G8QUL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

158190:SPIGRAPES RS16050
gene id: 158190:SPIGRAPES_RS16050
uniprot id: G8QR38
names: Similarity
messages: Belongs to the YicC/YloC family.

158190:SPIGRAPES RS10585
gene id: 158190:SPIGRAPES_RS10585
uniprot id: G8QRH8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

158190:SPIGRAPES RS01045
gene id: 158190:SPIGRAPES_RS01045
uniprot id: G8QUA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS01695
gene id: 158190:SPIGRAPES_RS01695
uniprot id: G8QVG8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

158190:SPIGRAPES RS12480
gene id: 158190:SPIGRAPES_RS12480
uniprot id: G8QU18
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS03415
gene id: 158190:SPIGRAPES_RS03415
uniprot id: G8QY26
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

158190:SPIGRAPES RS14475
gene id: 158190:SPIGRAPES_RS14475
uniprot id: G8QX76
names: Similarity
messages: Belongs to the thioredoxin family.

158190:SPIGRAPES RS15185
gene id: 158190:SPIGRAPES_RS15185
uniprot id: G8QYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS07465
gene id: 158190:SPIGRAPES_RS07465
uniprot id: G8QVM1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

158190:SPIGRAPES RS10370
gene id: 158190:SPIGRAPES_RS10370
uniprot id: G8QR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

158190:SPIGRAPES RS02995
gene id: 158190:SPIGRAPES_RS02995
uniprot id: G8QXF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS08890
gene id: 158190:SPIGRAPES_RS08890
uniprot id: G8QXM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

158190:SPIGRAPES RS08435
gene id: 158190:SPIGRAPES_RS08435
uniprot id: G8QWZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS15940
gene id: 158190:SPIGRAPES_RS15940
uniprot id: G8QQM1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

158190:SPIGRAPES RS12485
gene id: 158190:SPIGRAPES_RS12485
uniprot id: G8QU19
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

158190:SPIGRAPES RS01840
gene id: 158190:SPIGRAPES_RS01840
uniprot id: G8QVJ7
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS11110
gene id: 158190:SPIGRAPES_RS11110
uniprot id: G8QS08
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

158190:SPIGRAPES RS06245
gene id: 158190:SPIGRAPES_RS06245
uniprot id: G8QTA4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

158190:SPIGRAPES RS15000
gene id: 158190:SPIGRAPES_RS15000
uniprot id: G8QYB9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

158190:SPIGRAPES RS13455
gene id: 158190:SPIGRAPES_RS13455
uniprot id: G8QVE3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

158190:SPIGRAPES RS15420
gene id: 158190:SPIGRAPES_RS15420
uniprot id: G8QYY9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

158190:SPIGRAPES RS07580
gene id: 158190:SPIGRAPES_RS07580
uniprot id: G8QVP4
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS01705
gene id: 158190:SPIGRAPES_RS01705
uniprot id: G8QVH0
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

158190:SPIGRAPES RS10380
gene id: 158190:SPIGRAPES_RS10380
uniprot id: G8QR22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

158190:SPIGRAPES RS04405
gene id: 158190:SPIGRAPES_RS04405
uniprot id: G8QQT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

158190:SPIGRAPES RS05280
gene id: 158190:SPIGRAPES_RS05280
uniprot id: G8QRV6
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS06850
gene id: 158190:SPIGRAPES_RS06850
uniprot id: G8QUF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

158190:SPIGRAPES RS15410
gene id: 158190:SPIGRAPES_RS15410
uniprot id: G8QYY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

158190:SPIGRAPES RS14955
gene id: 158190:SPIGRAPES_RS14955
uniprot id: G8QYB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS02090
gene id: 158190:SPIGRAPES_RS02090
uniprot id: G8QW36
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS09460
gene id: 158190:SPIGRAPES_RS09460
uniprot id: G8QYS1
names: Similarity
messages: Belongs to the peptidase S41A family.

158190:SPIGRAPES RS10610
gene id: 158190:SPIGRAPES_RS10610
uniprot id: G8QRI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

158190:SPIGRAPES RS09290
gene id: 158190:SPIGRAPES_RS09290
uniprot id: G8QY99
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS05660
gene id: 158190:SPIGRAPES_RS05660
uniprot id: G8QSK1
names: Similarity
messages: Belongs to the Nth/MutY family.

158190:SPIGRAPES RS07070
gene id: 158190:SPIGRAPES_RS07070
uniprot id: G8QV06
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS13790
gene id: 158190:SPIGRAPES_RS13790
uniprot id: G8QVZ9
names: Similarity
messages: Belongs to the UMP kinase family.

158190:SPIGRAPES RS06595
gene id: 158190:SPIGRAPES_RS06595
uniprot id: G8QTW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

158190:SPIGRAPES RS14450
gene id: 158190:SPIGRAPES_RS14450
uniprot id: G8QX71
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS08780
gene id: 158190:SPIGRAPES_RS08780
uniprot id: G8QXK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

158190:SPIGRAPES RS06500
gene id: 158190:SPIGRAPES_RS06500
uniprot id: G8QTU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS01980
gene id: 158190:SPIGRAPES_RS01980
uniprot id: G8QW14
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

158190:SPIGRAPES RS00010
gene id: 158190:SPIGRAPES_RS00010
uniprot id: G8QSH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS03400
gene id: 158190:SPIGRAPES_RS03400
uniprot id: G8QY23
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS16035
gene id: 158190:SPIGRAPES_RS16035
uniprot id: G8QQN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

158190:SPIGRAPES RS09020
gene id: 158190:SPIGRAPES_RS09020
uniprot id: G8QY46
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

158190:SPIGRAPES RS12860
gene id: 158190:SPIGRAPES_RS12860
uniprot id: G8QUN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

158190:SPIGRAPES RS02050
gene id: 158190:SPIGRAPES_RS02050
uniprot id: G8QW28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

158190:SPIGRAPES RS04070
gene id: 158190:SPIGRAPES_RS04070
uniprot id: G8QQ73
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

158190:SPIGRAPES RS11060
gene id: 158190:SPIGRAPES_RS11060
uniprot id: G8QRZ8
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10290
gene id: 158190:SPIGRAPES_RS10290
uniprot id: G8QR04
names: Similarity
messages: Belongs to the YggT family.

158190:SPIGRAPES RS07555
gene id: 158190:SPIGRAPES_RS07555
uniprot id: G8QVN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS13560
gene id: 158190:SPIGRAPES_RS13560
uniprot id: G8QVV3
names: Similarity
messages: Belongs to the leucine-binding protein family.

158190:SPIGRAPES RS04845
gene id: 158190:SPIGRAPES_RS04845
uniprot id: G8QRF2
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS02140
gene id: 158190:SPIGRAPES_RS02140
uniprot id: G8QW46
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

158190:SPIGRAPES RS04750
gene id: 158190:SPIGRAPES_RS04750
uniprot id: G8QRD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS10600
gene id: 158190:SPIGRAPES_RS10600
uniprot id: G8QRI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

158190:SPIGRAPES RS07870
gene id: 158190:SPIGRAPES_RS07870
uniprot id: G8QW95
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

158190:SPIGRAPES RS10565
gene id: 158190:SPIGRAPES_RS10565
uniprot id: G8QRH5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

158190:SPIGRAPES RS10615
gene id: 158190:SPIGRAPES_RS10615
uniprot id: G8QRI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

158190:SPIGRAPES RS02115
gene id: 158190:SPIGRAPES_RS02115
uniprot id: G8QW41
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

158190:SPIGRAPES RS15945
gene id: 158190:SPIGRAPES_RS15945
uniprot id: G8QQM2
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS05220
gene id: 158190:SPIGRAPES_RS05220
uniprot id: G8QRU4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

158190:SPIGRAPES RS12520
gene id: 158190:SPIGRAPES_RS12520
uniprot id: G8QU26
names: Similarity
messages: Belongs to the class-I fumarase family.

158190:SPIGRAPES RS07960
gene id: 158190:SPIGRAPES_RS07960
uniprot id: G8QWB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS02825
gene id: 158190:SPIGRAPES_RS02825
uniprot id: G8QXC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS07645
gene id: 158190:SPIGRAPES_RS07645
uniprot id: G8QVQ7
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

158190:SPIGRAPES RS05940
gene id: 158190:SPIGRAPES_RS05940
uniprot id: G8QSQ4
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

158190:SPIGRAPES RS15205
gene id: 158190:SPIGRAPES_RS15205
uniprot id: G8QYF8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

158190:SPIGRAPES RS06510
gene id: 158190:SPIGRAPES_RS06510
uniprot id: G8QTU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS09640
gene id: 158190:SPIGRAPES_RS09640
uniprot id: G8QYV3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

158190:SPIGRAPES RS10750
gene id: 158190:SPIGRAPES_RS10750
uniprot id: G8QRL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

158190:SPIGRAPES RS13090
gene id: 158190:SPIGRAPES_RS13090
uniprot id: G8QUS9
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

158190:SPIGRAPES RS09775
gene id: 158190:SPIGRAPES_RS09775
uniprot id: G8QQA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS14535
gene id: 158190:SPIGRAPES_RS14535
uniprot id: G8QX88
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

158190:SPIGRAPES RS03785
gene id: 158190:SPIGRAPES_RS03785
uniprot id: G8QYN8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

158190:SPIGRAPES RS03150
gene id: 158190:SPIGRAPES_RS03150
uniprot id: G8QXX3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158190:SPIGRAPES RS09015
gene id: 158190:SPIGRAPES_RS09015
uniprot id: G8QY45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS03245
gene id: 158190:SPIGRAPES_RS03245
uniprot id: G8QXZ2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

158190:SPIGRAPES RS04660
gene id: 158190:SPIGRAPES_RS04660
uniprot id: G8QRB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS16240
gene id: 158190:SPIGRAPES_RS16240
uniprot id: G8QR75
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

158190:SPIGRAPES RS13450
gene id: 158190:SPIGRAPES_RS13450
uniprot id: G8QVE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

158190:SPIGRAPES RS05795
gene id: 158190:SPIGRAPES_RS05795
uniprot id: G8QSM5
names: Similarity
messages: Belongs to the aspartokinase family.

158190:SPIGRAPES RS08250
gene id: 158190:SPIGRAPES_RS08250
uniprot id: G8QWV8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS00650
gene id: 158190:SPIGRAPES_RS00650
uniprot id: G8QTN2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

158190:SPIGRAPES RS06605
gene id: 158190:SPIGRAPES_RS06605
uniprot id: G8QTW7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

158190:SPIGRAPES RS01635
gene id: 158190:SPIGRAPES_RS01635
uniprot id: G8QVF6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

158190:SPIGRAPES RS12500
gene id: 158190:SPIGRAPES_RS12500
uniprot id: G8QU22
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

158190:SPIGRAPES RS01155
gene id: 158190:SPIGRAPES_RS01155
uniprot id: G8QUC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS07715
gene id: 158190:SPIGRAPES_RS07715
uniprot id: G8QVS1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

158190:SPIGRAPES RS06765
gene id: 158190:SPIGRAPES_RS06765
uniprot id: G8QUE3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

158190:SPIGRAPES RS14665
gene id: 158190:SPIGRAPES_RS14665
uniprot id: G8QXQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

158190:SPIGRAPES RS03240
gene id: 158190:SPIGRAPES_RS03240
uniprot id: G8QXZ1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS12625
gene id: 158190:SPIGRAPES_RS12625
uniprot id: G8QU47
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

158190:SPIGRAPES RS02770
gene id: 158190:SPIGRAPES_RS02770
uniprot id: G8QXA9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15640
gene id: 158190:SPIGRAPES_RS15640
uniprot id: G8QZ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS08480
gene id: 158190:SPIGRAPES_RS08480
uniprot id: G8QX01
names: Similarity
messages: Belongs to the UPF0597 family.

158190:SPIGRAPES RS03210
gene id: 158190:SPIGRAPES_RS03210
uniprot id: G8QXY5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS13250
gene id: 158190:SPIGRAPES_RS13250
uniprot id: G8QVA3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

158190:SPIGRAPES RS05635
gene id: 158190:SPIGRAPES_RS05635
uniprot id: G8QS96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

158190:SPIGRAPES RS12495
gene id: 158190:SPIGRAPES_RS12495
uniprot id: G8QU21
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

158190:SPIGRAPES RS03185
gene id: 158190:SPIGRAPES_RS03185
uniprot id: G8QXY0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

158190:SPIGRAPES RS00165
gene id: 158190:SPIGRAPES_RS00165
uniprot id: G8QSZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

158190:SPIGRAPES RS13980
gene id: 158190:SPIGRAPES_RS13980
uniprot id: G8QWI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

158190:SPIGRAPES RS01625
gene id: 158190:SPIGRAPES_RS01625
uniprot id: G8QVF4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

158190:SPIGRAPES RS02085
gene id: 158190:SPIGRAPES_RS02085
uniprot id: G8QW35
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

158190:SPIGRAPES RS14735
gene id: 158190:SPIGRAPES_RS14735
uniprot id: G8QXR9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS01670
gene id: 158190:SPIGRAPES_RS01670
uniprot id: G8QVG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

158190:SPIGRAPES RS09405
gene id: 158190:SPIGRAPES_RS09405
uniprot id: G8QYR0
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS12640
gene id: 158190:SPIGRAPES_RS12640
uniprot id: G8QU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS11320
gene id: 158190:SPIGRAPES_RS11320
uniprot id: G8QSB9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

158190:SPIGRAPES RS02350
gene id: 158190:SPIGRAPES_RS02350
uniprot id: G8QWN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

158190:SPIGRAPES RS02070
gene id: 158190:SPIGRAPES_RS02070
uniprot id: G8QW32
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS06955
gene id: 158190:SPIGRAPES_RS06955
uniprot id: G8QUH9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS14640
gene id: 158190:SPIGRAPES_RS14640
uniprot id: G8QXQ0
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS05990
gene id: 158190:SPIGRAPES_RS05990
uniprot id: G8QSR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

158190:SPIGRAPES RS09310
gene id: 158190:SPIGRAPES_RS09310
uniprot id: G8QYA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS15295
gene id: 158190:SPIGRAPES_RS15295
uniprot id: G8QYH5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

158190:SPIGRAPES RS02875
gene id: 158190:SPIGRAPES_RS02875
uniprot id: G8QXC8
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS07525
gene id: 158190:SPIGRAPES_RS07525
uniprot id: G8QVN3
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

158190:SPIGRAPES RS12670
gene id: 158190:SPIGRAPES_RS12670
uniprot id: G8QU56
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

158190:SPIGRAPES RS12725
gene id: 158190:SPIGRAPES_RS12725
uniprot id: G8QU67
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

158190:SPIGRAPES RS08825
gene id: 158190:SPIGRAPES_RS08825
uniprot id: G8QXK9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS11190
gene id: 158190:SPIGRAPES_RS11190
uniprot id: G8QS24
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS05150
gene id: 158190:SPIGRAPES_RS05150
uniprot id: G8QRT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

158190:SPIGRAPES RS05730
gene id: 158190:SPIGRAPES_RS05730
uniprot id: G8QSL3
names: Similarity
messages: Belongs to the UPF0597 family.

158190:SPIGRAPES RS14740
gene id: 158190:SPIGRAPES_RS14740
uniprot id: G8QXS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

158190:SPIGRAPES RS12900
gene id: 158190:SPIGRAPES_RS12900
uniprot id: G8QUP1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

158190:SPIGRAPES RS01950
gene id: 158190:SPIGRAPES_RS01950
uniprot id: G8QVL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

158190:SPIGRAPES RS14150
gene id: 158190:SPIGRAPES_RS14150
uniprot id: G8QWL9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

158190:SPIGRAPES RS15015
gene id: 158190:SPIGRAPES_RS15015
uniprot id: G8QYC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

158190:SPIGRAPES RS12795
gene id: 158190:SPIGRAPES_RS12795
uniprot id: G8QUM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS07005
gene id: 158190:SPIGRAPES_RS07005
uniprot id: G8QUI9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS11460
gene id: 158190:SPIGRAPES_RS11460
uniprot id: G8QSE6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

158190:SPIGRAPES RS13435
gene id: 158190:SPIGRAPES_RS13435
uniprot id: G8QVD9
names: Subcellular Location Annotation
messages: Cytoplasm

158190:SPIGRAPES RS06465
gene id: 158190:SPIGRAPES_RS06465
uniprot id: G8QTT9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

158190:SPIGRAPES RS10810
gene id: 158190:SPIGRAPES_RS10810
uniprot id: G8QRM4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

158190:SPIGRAPES RS04465
gene id: 158190:SPIGRAPES_RS04465
uniprot id: G8QQU8
names: Similarity
messages: Belongs to the ice-binding protein family.

158190:SPIGRAPES RS09835
gene id: 158190:SPIGRAPES_RS09835
uniprot id: G8QQB9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

158190:SPIGRAPES RS04905
gene id: 158190:SPIGRAPES_RS04905
uniprot id: G8QRN3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

158190:SPIGRAPES RS10590
gene id: 158190:SPIGRAPES_RS10590
uniprot id: G8QRH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

158190:SPIGRAPES RS02100
gene id: 158190:SPIGRAPES_RS02100
uniprot id: G8QW38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

158190:SPIGRAPES RS06810
gene id: 158190:SPIGRAPES_RS06810
uniprot id: G8QUF0
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS17000
gene id: 158190:SPIGRAPES_RS17000
uniprot id: G8QUF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

158190:SPIGRAPES RS05140
gene id: 158190:SPIGRAPES_RS05140
uniprot id: G8QRS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

158190:SPIGRAPES RS07550
gene id: 158190:SPIGRAPES_RS07550
uniprot id: G8QVN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS05125
gene id: 158190:SPIGRAPES_RS05125
uniprot id: G8QRS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS02405
gene id: 158190:SPIGRAPES_RS02405
uniprot id: G8QWP6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

158190:SPIGRAPES RS11175
gene id: 158190:SPIGRAPES_RS11175
uniprot id: G8QS21
names: Similarity
messages: Belongs to the pyruvate kinase family.

158190:SPIGRAPES RS13605
gene id: 158190:SPIGRAPES_RS13605
uniprot id: G8QVW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS04780
gene id: 158190:SPIGRAPES_RS04780
uniprot id: G8QRD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

158190:SPIGRAPES RS05130
gene id: 158190:SPIGRAPES_RS05130
uniprot id: G8QRS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

158190:SPIGRAPES RS11065
gene id: 158190:SPIGRAPES_RS11065
uniprot id: G8QRZ9
names: Similarity
messages: Belongs to the pirin family.

158190:SPIGRAPES RS13325
gene id: 158190:SPIGRAPES_RS13325
uniprot id: G8QVB8
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

158190:SPIGRAPES RS04695
gene id: 158190:SPIGRAPES_RS04695
uniprot id: G8QRC2
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

158190:SPIGRAPES RS12605
gene id: 158190:SPIGRAPES_RS12605
uniprot id: G8QU43
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

158190:SPIGRAPES RS03495
gene id: 158190:SPIGRAPES_RS03495
uniprot id: G8QYI5
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS16325
gene id: 158190:SPIGRAPES_RS16325
uniprot id: G8QR92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS04495
gene id: 158190:SPIGRAPES_RS04495
uniprot id: G8QQV4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

158190:SPIGRAPES RS06555
gene id: 158190:SPIGRAPES_RS06555
uniprot id: G8QTV7
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS03340
gene id: 158190:SPIGRAPES_RS03340
uniprot id: G8QY11
names: Similarity
messages: Belongs to the citrate synthase family.

158190:SPIGRAPES RS02020
gene id: 158190:SPIGRAPES_RS02020
uniprot id: G8QW22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

158190:SPIGRAPES RS16055
gene id: 158190:SPIGRAPES_RS16055
uniprot id: G8QR39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

158190:SPIGRAPES RS02595
gene id: 158190:SPIGRAPES_RS02595
uniprot id: G8QWT4
names: Similarity
messages: Belongs to the peptidase M29 family.

158190:SPIGRAPES RS09010
gene id: 158190:SPIGRAPES_RS09010
uniprot id: G8QY44
names: Similarity
messages: Belongs to the glutamine synthetase family.

158190:SPIGRAPES RS04365
gene id: 158190:SPIGRAPES_RS04365
uniprot id: G8QQS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

158190:SPIGRAPES RS13880
gene id: 158190:SPIGRAPES_RS13880
uniprot id: G8QWG4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

158190:SPIGRAPES RS02965
gene id: 158190:SPIGRAPES_RS02965
uniprot id: G8QXE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

158190:SPIGRAPES RS10755
gene id: 158190:SPIGRAPES_RS10755
uniprot id: G8QRL3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

158190:SPIGRAPES RS05445
gene id: 158190:SPIGRAPES_RS05445
uniprot id: G8QS60
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

158190:SPIGRAPES RS14805
gene id: 158190:SPIGRAPES_RS14805
uniprot id: G8QXT3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

158190:SPIGRAPES RS09625
gene id: 158190:SPIGRAPES_RS09625
uniprot id: G8QYV0
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

158190:SPIGRAPES RS03470
gene id: 158190:SPIGRAPES_RS03470
uniprot id: G8QYI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

158190:SPIGRAPES RS16110
gene id: 158190:SPIGRAPES_RS16110
uniprot id: G8QR49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

158190:SPIGRAPES RS16195
gene id: 158190:SPIGRAPES_RS16195
uniprot id: G8QR66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

158190:SPIGRAPES RS12560
gene id: 158190:SPIGRAPES_RS12560
uniprot id: G8QU34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

158190:SPIGRAPES RS13045
gene id: 158190:SPIGRAPES_RS13045
uniprot id: G8QUS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

158190:SPIGRAPES RS10625
gene id: 158190:SPIGRAPES_RS10625
uniprot id: G8QRI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

158190:SPIGRAPES RS09880
gene id: 158190:SPIGRAPES_RS09880
uniprot id: G8QQC8
names: Similarity
messages: Belongs to the BMP lipoprotein family.

158190:SPIGRAPES RS07390
gene id: 158190:SPIGRAPES_RS07390
uniprot id: G8QV64
names: Similarity
messages: Belongs to the fabD family.

158190:SPIGRAPES RS05665
gene id: 158190:SPIGRAPES_RS05665
uniprot id: G8QSK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

158190:SPIGRAPES RS15900
gene id: 158190:SPIGRAPES_RS15900
uniprot id: G8QQL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

158190:SPIGRAPES RS05640
gene id: 158190:SPIGRAPES_RS05640
uniprot id: G8QSJ7
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

158190:SPIGRAPES RS12690
gene id: 158190:SPIGRAPES_RS12690
uniprot id: G8QU60
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS09900
gene id: 158190:SPIGRAPES_RS09900
uniprot id: G8QQD2
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

158190:SPIGRAPES RS02710
gene id: 158190:SPIGRAPES_RS02710
uniprot id: G8QX97
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

158190:SPIGRAPES RS06520
gene id: 158190:SPIGRAPES_RS06520
uniprot id: G8QTV0
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15845
gene id: 158190:SPIGRAPES_RS15845
uniprot id: G8QQK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

158190:SPIGRAPES RS08615
gene id: 158190:SPIGRAPES_RS08615
uniprot id: G8QXG8
names: Similarity
messages: Belongs to the leucine-binding protein family.

158190:SPIGRAPES RS06440
gene id: 158190:SPIGRAPES_RS06440
uniprot id: G8QTT4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

158190:SPIGRAPES RS02780
gene id: 158190:SPIGRAPES_RS02780
uniprot id: G8QXB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

158190:SPIGRAPES RS00420
gene id: 158190:SPIGRAPES_RS00420
uniprot id: G8QT44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

158190:SPIGRAPES RS02480
gene id: 158190:SPIGRAPES_RS02480
uniprot id: G8QWR2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

158190:SPIGRAPES RS03080
gene id: 158190:SPIGRAPES_RS03080
uniprot id: G8QXV9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS07365
gene id: 158190:SPIGRAPES_RS07365
uniprot id: G8QV59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

158190:SPIGRAPES RS11040
gene id: 158190:SPIGRAPES_RS11040
uniprot id: G8QRZ4
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS13225
gene id: 158190:SPIGRAPES_RS13225
uniprot id: G8QV98
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

158190:SPIGRAPES RS02790
gene id: 158190:SPIGRAPES_RS02790
uniprot id: G8QXB3
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

158190:SPIGRAPES RS12650
gene id: 158190:SPIGRAPES_RS12650
uniprot id: G8QU52
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

158190:SPIGRAPES RS10505
gene id: 158190:SPIGRAPES_RS10505
uniprot id: G8QRG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS15700
gene id: 158190:SPIGRAPES_RS15700
uniprot id: G8QQH4
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

158190:SPIGRAPES RS11290
gene id: 158190:SPIGRAPES_RS11290
uniprot id: G8QSB3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

158190:SPIGRAPES RS09135
gene id: 158190:SPIGRAPES_RS09135
uniprot id: G8QY68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS10665
gene id: 158190:SPIGRAPES_RS10665
uniprot id: G8QRJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

158190:SPIGRAPES RS08660
gene id: 158190:SPIGRAPES_RS08660
uniprot id: G8QXH7
names: Similarity
messages: Belongs to the leucine-binding protein family.

158190:SPIGRAPES RS13740
gene id: 158190:SPIGRAPES_RS13740
uniprot id: G8QVY9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

158190:SPIGRAPES RS13475
gene id: 158190:SPIGRAPES_RS13475
uniprot id: G8QVT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

158190:SPIGRAPES RS04920
gene id: 158190:SPIGRAPES_RS04920
uniprot id: G8QRN6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

158190:SPIGRAPES RS03635
gene id: 158190:SPIGRAPES_RS03635
uniprot id: G8QYK9
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

158190:SPIGRAPES RS10915
gene id: 158190:SPIGRAPES_RS10915
uniprot id: G8QRW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

158190:SPIGRAPES RS04020
gene id: 158190:SPIGRAPES_RS04020
uniprot id: G8QQ63
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS14995
gene id: 158190:SPIGRAPES_RS14995
uniprot id: G8QYB8
names: Subcellular Location Annotation
messages: Nucleus

158190:SPIGRAPES RS00415
gene id: 158190:SPIGRAPES_RS00415
uniprot id: G8QT43
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

158190:SPIGRAPES RS05815
gene id: 158190:SPIGRAPES_RS05815
uniprot id: G8QSM9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS11090
gene id: 158190:SPIGRAPES_RS11090
uniprot id: G8QS04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

158190:SPIGRAPES RS10730
gene id: 158190:SPIGRAPES_RS10730
uniprot id: G8QRK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

158190:SPIGRAPES RS05740
gene id: 158190:SPIGRAPES_RS05740
uniprot id: G8QSL5
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15095
gene id: 158190:SPIGRAPES_RS15095
uniprot id: G8QYD7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

158190:SPIGRAPES RS00080
gene id: 158190:SPIGRAPES_RS00080
uniprot id: G8QSI5
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10580
gene id: 158190:SPIGRAPES_RS10580
uniprot id: G8QRH7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

158190:SPIGRAPES RS15040
gene id: 158190:SPIGRAPES_RS15040
uniprot id: G8QYC6
names: Similarity
messages: Belongs to the aldose epimerase family.

158190:SPIGRAPES RS00300
gene id: 158190:SPIGRAPES_RS00300
uniprot id: G8QT20
names: Similarity
messages: Belongs to the serpin family.

158190:SPIGRAPES RS09165
gene id: 158190:SPIGRAPES_RS09165
uniprot id: G8QY74
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

158190:SPIGRAPES RS15745
gene id: 158190:SPIGRAPES_RS15745
uniprot id: G8QQI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS15580
gene id: 158190:SPIGRAPES_RS15580
uniprot id: G8QZ20
names: Similarity
messages: Belongs to the phosphoglycerate kinase family.

158190:SPIGRAPES RS06645
gene id: 158190:SPIGRAPES_RS06645
uniprot id: G8QTX5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

158190:SPIGRAPES RS00400
gene id: 158190:SPIGRAPES_RS00400
uniprot id: G8QT40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

158190:SPIGRAPES RS05450
gene id: 158190:SPIGRAPES_RS05450
uniprot id: G8QS61
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS06910
gene id: 158190:SPIGRAPES_RS06910
uniprot id: G8QUH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

158190:SPIGRAPES RS13020
gene id: 158190:SPIGRAPES_RS13020
uniprot id: G8QUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS00145
gene id: 158190:SPIGRAPES_RS00145
uniprot id: G8QSJ6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

158190:SPIGRAPES RS10650
gene id: 158190:SPIGRAPES_RS10650
uniprot id: G8QRJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

158190:SPIGRAPES RS14145
gene id: 158190:SPIGRAPES_RS14145
uniprot id: G8QWL8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

158190:SPIGRAPES RS10895
gene id: 158190:SPIGRAPES_RS10895
uniprot id: G8QRW5
names: Function
names: Similarity
messages: Belongs to the bacterial histone-like protein family.
messages: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.

158190:SPIGRAPES RS03195
gene id: 158190:SPIGRAPES_RS03195
uniprot id: G8QXY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

158190:SPIGRAPES RS15090
gene id: 158190:SPIGRAPES_RS15090
uniprot id: G8QYD6
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS01965
gene id: 158190:SPIGRAPES_RS01965
uniprot id: G8QW11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

158190:SPIGRAPES RS10000
gene id: 158190:SPIGRAPES_RS10000
uniprot id: G8QQF2
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

158190:SPIGRAPES RS10675
gene id: 158190:SPIGRAPES_RS10675
uniprot id: G8QRJ6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

158190:SPIGRAPES RS08380
gene id: 158190:SPIGRAPES_RS08380
uniprot id: G8QWY2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

158190:SPIGRAPES RS09040
gene id: 158190:SPIGRAPES_RS09040
uniprot id: G8QY49
names: Function
names: Similarity
messages: Belongs to the acyltransferase CrtO family.
messages: Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i.e. the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin. This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains.

158190:SPIGRAPES RS15975
gene id: 158190:SPIGRAPES_RS15975
uniprot id: G8QQM7
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS05600
gene id: 158190:SPIGRAPES_RS05600
uniprot id: G8QS89
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

158190:SPIGRAPES RS10345
gene id: 158190:SPIGRAPES_RS10345
uniprot id: G8QR15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

158190:SPIGRAPES RS00585
gene id: 158190:SPIGRAPES_RS00585
uniprot id: G8QTL9
names: Similarity
messages: Belongs to the carbamate kinase family.

158190:SPIGRAPES RS09235
gene id: 158190:SPIGRAPES_RS09235
uniprot id: G8QY88
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

158190:SPIGRAPES RS02890
gene id: 158190:SPIGRAPES_RS02890
uniprot id: G8QXD1
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

158190:SPIGRAPES RS02560
gene id: 158190:SPIGRAPES_RS02560
uniprot id: G8QWS7
names: Similarity
messages: Belongs to the sulfatase family.

158190:SPIGRAPES RS16170
gene id: 158190:SPIGRAPES_RS16170
uniprot id: G8QR61
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

158190:SPIGRAPES RS15775
gene id: 158190:SPIGRAPES_RS15775
uniprot id: G8QQI8
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS08060
gene id: 158190:SPIGRAPES_RS08060
uniprot id: G8QWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS05190
gene id: 158190:SPIGRAPES_RS05190
uniprot id: G8QRT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS13835
gene id: 158190:SPIGRAPES_RS13835
uniprot id: G8QW07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

158190:SPIGRAPES RS09895
gene id: 158190:SPIGRAPES_RS09895
uniprot id: G8QQD1
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS03235
gene id: 158190:SPIGRAPES_RS03235
uniprot id: G8QXZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

158190:SPIGRAPES RS04955
gene id: 158190:SPIGRAPES_RS04955
uniprot id: G8QRP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

158190:SPIGRAPES RS04055
gene id: 158190:SPIGRAPES_RS04055
uniprot id: G8QQ70
names: Similarity
messages: Belongs to the UbiD family.

158190:SPIGRAPES RS10440
gene id: 158190:SPIGRAPES_RS10440
uniprot id: G8QR34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

158190:SPIGRAPES RS04515
gene id: 158190:SPIGRAPES_RS04515
uniprot id: G8QQV8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

158190:SPIGRAPES RS15705
gene id: 158190:SPIGRAPES_RS15705
uniprot id: G8QQH5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

158190:SPIGRAPES RS11305
gene id: 158190:SPIGRAPES_RS11305
uniprot id: G8QSB6
names: Similarity
messages: Belongs to the creatininase superfamily.

158190:SPIGRAPES RS05430
gene id: 158190:SPIGRAPES_RS05430
uniprot id: G8QS57
names: Similarity
messages: Belongs to the FGGY kinase family.

158190:SPIGRAPES RS13610
gene id: 158190:SPIGRAPES_RS13610
uniprot id: G8QVW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

158190:SPIGRAPES RS00785
gene id: 158190:SPIGRAPES_RS00785
uniprot id: G8QTQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS12770
gene id: 158190:SPIGRAPES_RS12770
uniprot id: G8QUL5
names: Subcellular Location Annotation
messages: Cytoplasm

158190:SPIGRAPES RS02840
gene id: 158190:SPIGRAPES_RS02840
uniprot id: G8QXC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

158190:SPIGRAPES RS03180
gene id: 158190:SPIGRAPES_RS03180
uniprot id: G8QXX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

158190:SPIGRAPES RS14675
gene id: 158190:SPIGRAPES_RS14675
uniprot id: G8QXQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS09370
gene id: 158190:SPIGRAPES_RS09370
uniprot id: G8QYQ3
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

158190:SPIGRAPES RS04510
gene id: 158190:SPIGRAPES_RS04510
uniprot id: G8QQV7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

158190:SPIGRAPES RS11770
gene id: 158190:SPIGRAPES_RS11770
uniprot id: G8QSV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS07510
gene id: 158190:SPIGRAPES_RS07510
uniprot id: G8QVN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS12695
gene id: 158190:SPIGRAPES_RS12695
uniprot id: G8QU61
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS04280
gene id: 158190:SPIGRAPES_RS04280
uniprot id: G8QQR2
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10275
gene id: 158190:SPIGRAPES_RS10275
uniprot id: G8QR01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

158190:SPIGRAPES RS07150
gene id: 158190:SPIGRAPES_RS07150
uniprot id: G8QV15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

158190:SPIGRAPES RS10640
gene id: 158190:SPIGRAPES_RS10640
uniprot id: G8QRI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

158190:SPIGRAPES RS07130
gene id: 158190:SPIGRAPES_RS07130
uniprot id: G8QV11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS11160
gene id: 158190:SPIGRAPES_RS11160
uniprot id: G8QS18
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS12665
gene id: 158190:SPIGRAPES_RS12665
uniprot id: G8QU55
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

158190:SPIGRAPES RS12080
gene id: 158190:SPIGRAPES_RS12080
uniprot id: G8QTF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS04220
gene id: 158190:SPIGRAPES_RS04220
uniprot id: G8QQQ0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

158190:SPIGRAPES RS03480
gene id: 158190:SPIGRAPES_RS03480
uniprot id: G8QYI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

158190:SPIGRAPES RS05200
gene id: 158190:SPIGRAPES_RS05200
uniprot id: G8QRU0
names: Similarity
messages: Belongs to the DtxR/MntR family.

158190:SPIGRAPES RS06635
gene id: 158190:SPIGRAPES_RS06635
uniprot id: G8QTX3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

158190:SPIGRAPES RS00975
gene id: 158190:SPIGRAPES_RS00975
uniprot id: G8QU92
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

158190:SPIGRAPES RS03715
gene id: 158190:SPIGRAPES_RS03715
uniprot id: G8QYM4
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS00465
gene id: 158190:SPIGRAPES_RS00465
uniprot id: G8QT53
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

158190:SPIGRAPES RS14545
gene id: 158190:SPIGRAPES_RS14545
uniprot id: G8QX90
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

158190:SPIGRAPES RS06895
gene id: 158190:SPIGRAPES_RS06895
uniprot id: G8QUG6
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

158190:SPIGRAPES RS11925
gene id: 158190:SPIGRAPES_RS11925
uniprot id: G8QSX9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS01780
gene id: 158190:SPIGRAPES_RS01780
uniprot id: G8QVI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

158190:SPIGRAPES RS01540
gene id: 158190:SPIGRAPES_RS01540
uniprot id: G8QUZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS05120
gene id: 158190:SPIGRAPES_RS05120
uniprot id: G8QRS4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

158190:SPIGRAPES RS12645
gene id: 158190:SPIGRAPES_RS12645
uniprot id: G8QU51
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

158190:SPIGRAPES RS02435
gene id: 158190:SPIGRAPES_RS02435
uniprot id: G8QWQ2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

158190:SPIGRAPES RS10925
gene id: 158190:SPIGRAPES_RS10925
uniprot id: G8QRX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

158190:SPIGRAPES RS05185
gene id: 158190:SPIGRAPES_RS05185
uniprot id: G8QRT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS06575
gene id: 158190:SPIGRAPES_RS06575
uniprot id: G8QTW1
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

158190:SPIGRAPES RS05610
gene id: 158190:SPIGRAPES_RS05610
uniprot id: G8QS91
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

158190:SPIGRAPES RS09100
gene id: 158190:SPIGRAPES_RS09100
uniprot id: G8QY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS13440
gene id: 158190:SPIGRAPES_RS13440
uniprot id: G8QVE0
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS00805
gene id: 158190:SPIGRAPES_RS00805
uniprot id: G8QTR3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

158190:SPIGRAPES RS11115
gene id: 158190:SPIGRAPES_RS11115
uniprot id: G8QS09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158190:SPIGRAPES RS13190
gene id: 158190:SPIGRAPES_RS13190
uniprot id: G8QV91
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS04350
gene id: 158190:SPIGRAPES_RS04350
uniprot id: G8QQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS02940
gene id: 158190:SPIGRAPES_RS02940
uniprot id: G8QXE1
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS09510
gene id: 158190:SPIGRAPES_RS09510
uniprot id: G8QYT1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS00895
gene id: 158190:SPIGRAPES_RS00895
uniprot id: G8QU76
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS01785
gene id: 158190:SPIGRAPES_RS01785
uniprot id: G8QVI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

158190:SPIGRAPES RS13215
gene id: 158190:SPIGRAPES_RS13215
uniprot id: G8QV96
names: Similarity
messages: Belongs to the MEMO1 family.

158190:SPIGRAPES RS05145
gene id: 158190:SPIGRAPES_RS05145
uniprot id: G8QRS9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

158190:SPIGRAPES RS09840
gene id: 158190:SPIGRAPES_RS09840
uniprot id: G8QQC0
names: Similarity
messages: Belongs to the UxaA family.

158190:SPIGRAPES RS05155
gene id: 158190:SPIGRAPES_RS05155
uniprot id: G8QRT1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS05825
gene id: 158190:SPIGRAPES_RS05825
uniprot id: G8QSN1
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

158190:SPIGRAPES RS08475
gene id: 158190:SPIGRAPES_RS08475
uniprot id: G8QX00
names: Similarity
messages: Belongs to the DapA family.

158190:SPIGRAPES RS14935
gene id: 158190:SPIGRAPES_RS14935
uniprot id: G8QYA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158190:SPIGRAPES RS05160
gene id: 158190:SPIGRAPES_RS05160
uniprot id: G8QRT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

158190:SPIGRAPES RS02475
gene id: 158190:SPIGRAPES_RS02475
uniprot id: G8QWR1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

158190:SPIGRAPES RS06660
gene id: 158190:SPIGRAPES_RS06660
uniprot id: G8QTX9
names: Similarity
messages: Belongs to the UPF0251 family.

158190:SPIGRAPES RS04810
gene id: 158190:SPIGRAPES_RS04810
uniprot id: G8QRE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS00375
gene id: 158190:SPIGRAPES_RS00375
uniprot id: G8QT35
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

158190:SPIGRAPES RS04645
gene id: 158190:SPIGRAPES_RS04645
uniprot id: G8QRB2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

158190:SPIGRAPES RS07485
gene id: 158190:SPIGRAPES_RS07485
uniprot id: G8QVM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS15270
gene id: 158190:SPIGRAPES_RS15270
uniprot id: G8QYH0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

158190:SPIGRAPES RS14815
gene id: 158190:SPIGRAPES_RS14815
uniprot id: G8QXT5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

158190:SPIGRAPES RS06945
gene id: 158190:SPIGRAPES_RS06945
uniprot id: G8QUH7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

158190:SPIGRAPES RS01620
gene id: 158190:SPIGRAPES_RS01620
uniprot id: G8QVF3
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10635
gene id: 158190:SPIGRAPES_RS10635
uniprot id: G8QRI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

158190:SPIGRAPES RS10385
gene id: 158190:SPIGRAPES_RS10385
uniprot id: G8QR23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

158190:SPIGRAPES RS08720
gene id: 158190:SPIGRAPES_RS08720
uniprot id: G8QXI8
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS00070
gene id: 158190:SPIGRAPES_RS00070
uniprot id: G8QSI3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

158190:SPIGRAPES RS10185
gene id: 158190:SPIGRAPES_RS10185
uniprot id: G8QQZ1
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS00615
gene id: 158190:SPIGRAPES_RS00615
uniprot id: G8QTM5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

158190:SPIGRAPES RS16200
gene id: 158190:SPIGRAPES_RS16200
uniprot id: G8QR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

158190:SPIGRAPES RS12945
gene id: 158190:SPIGRAPES_RS12945
uniprot id: G8QUQ0
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15135
gene id: 158190:SPIGRAPES_RS15135
uniprot id: G8QYE4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158190:SPIGRAPES RS02345
gene id: 158190:SPIGRAPES_RS02345
uniprot id: G8QWN4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

158190:SPIGRAPES RS15045
gene id: 158190:SPIGRAPES_RS15045
uniprot id: G8QYC7
names: Similarity
messages: Belongs to the hyi family.

158190:SPIGRAPES RS06470
gene id: 158190:SPIGRAPES_RS06470
uniprot id: G8QTU0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

158190:SPIGRAPES RS09745
gene id: 158190:SPIGRAPES_RS09745
uniprot id: G8QQA1
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

158190:SPIGRAPES RS02980
gene id: 158190:SPIGRAPES_RS02980
uniprot id: G8QXE9
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

158190:SPIGRAPES RS01590
gene id: 158190:SPIGRAPES_RS01590
uniprot id: G8QVE8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

158190:SPIGRAPES RS03155
gene id: 158190:SPIGRAPES_RS03155
uniprot id: G8QXX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

158190:SPIGRAPES RS02455
gene id: 158190:SPIGRAPES_RS02455
uniprot id: G8QWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

158190:SPIGRAPES RS13670
gene id: 158190:SPIGRAPES_RS13670
uniprot id: G8QVX5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

158190:SPIGRAPES RS15265
gene id: 158190:SPIGRAPES_RS15265
uniprot id: G8QYG9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

158190:SPIGRAPES RS03370
gene id: 158190:SPIGRAPES_RS03370
uniprot id: G8QY17
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

158190:SPIGRAPES RS07770
gene id: 158190:SPIGRAPES_RS07770
uniprot id: G8QVT0
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS03160
gene id: 158190:SPIGRAPES_RS03160
uniprot id: G8QXX5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

158190:SPIGRAPES RS04595
gene id: 158190:SPIGRAPES_RS04595
uniprot id: G8QRA2
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10535
gene id: 158190:SPIGRAPES_RS10535
uniprot id: G8QRH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

158190:SPIGRAPES RS07380
gene id: 158190:SPIGRAPES_RS07380
uniprot id: G8QV62
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

158190:SPIGRAPES RS07285
gene id: 158190:SPIGRAPES_RS07285
uniprot id: G8QV43
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS16585
gene id: 158190:SPIGRAPES_RS16585
uniprot id: G8QY35
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

158190:SPIGRAPES RS05400
gene id: 158190:SPIGRAPES_RS05400
uniprot id: G8QS51
names: Similarity
messages: Belongs to the TrpR family.

158190:SPIGRAPES RS14790
gene id: 158190:SPIGRAPES_RS14790
uniprot id: G8QXT0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

158190:SPIGRAPES RS10375
gene id: 158190:SPIGRAPES_RS10375
uniprot id: G8QR21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

158190:SPIGRAPES RS08695
gene id: 158190:SPIGRAPES_RS08695
uniprot id: G8QXI4
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15280
gene id: 158190:SPIGRAPES_RS15280
uniprot id: G8QYH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

158190:SPIGRAPES RS16185
gene id: 158190:SPIGRAPES_RS16185
uniprot id: G8QR64
names: Similarity
messages: Belongs to the UPF0178 family.

158190:SPIGRAPES RS02625
gene id: 158190:SPIGRAPES_RS02625
uniprot id: G8QWT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

158190:SPIGRAPES RS10955
gene id: 158190:SPIGRAPES_RS10955
uniprot id: G8QRX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

158190:SPIGRAPES RS01285
gene id: 158190:SPIGRAPES_RS01285
uniprot id: G8QUU7
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS14380
gene id: 158190:SPIGRAPES_RS14380
uniprot id: G8QX56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS08675
gene id: 158190:SPIGRAPES_RS08675
uniprot id: G8QXI0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

158190:SPIGRAPES RS12460
gene id: 158190:SPIGRAPES_RS12460
uniprot id: G8QU14
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS09715
gene id: 158190:SPIGRAPES_RS09715
uniprot id: G8QYW3
names: Similarity
messages: Belongs to the IMPACT family.

158190:SPIGRAPES RS10090
gene id: 158190:SPIGRAPES_RS10090
uniprot id: G8QQW7
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS06335
gene id: 158190:SPIGRAPES_RS06335
uniprot id: G8QTC1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

158190:SPIGRAPES RS01260
gene id: 158190:SPIGRAPES_RS01260
uniprot id: G8QUU2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

158190:SPIGRAPES RS09580
gene id: 158190:SPIGRAPES_RS09580
uniprot id: G8QYU5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

158190:SPIGRAPES RS11600
gene id: 158190:SPIGRAPES_RS11600
uniprot id: G8QSR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

158190:SPIGRAPES RS02990
gene id: 158190:SPIGRAPES_RS02990
uniprot id: G8QXF1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

158190:SPIGRAPES RS09890
gene id: 158190:SPIGRAPES_RS09890
uniprot id: G8QQD0
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15515
gene id: 158190:SPIGRAPES_RS15515
uniprot id: G8QZ08
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

158190:SPIGRAPES RS10330
gene id: 158190:SPIGRAPES_RS10330
uniprot id: G8QR12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

158190:SPIGRAPES RS03565
gene id: 158190:SPIGRAPES_RS03565
uniprot id: G8QYJ9
names: Similarity
messages: Belongs to the BMP lipoprotein family.

158190:SPIGRAPES RS01335
gene id: 158190:SPIGRAPES_RS01335
uniprot id: G8QUV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS00020
gene id: 158190:SPIGRAPES_RS00020
uniprot id: G8QSH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

158190:SPIGRAPES RS08540
gene id: 158190:SPIGRAPES_RS08540
uniprot id: G8QX11
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

158190:SPIGRAPES RS07955
gene id: 158190:SPIGRAPES_RS07955
uniprot id: G8QWB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS01595
gene id: 158190:SPIGRAPES_RS01595
uniprot id: G8QVE9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

158190:SPIGRAPES RS15905
gene id: 158190:SPIGRAPES_RS15905
uniprot id: G8QQL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS16565
gene id: 158190:SPIGRAPES_RS16565
uniprot id: G8QWE4
names: Similarity
messages: Belongs to the SecB family.

158190:SPIGRAPES RS14585
gene id: 158190:SPIGRAPES_RS14585
uniprot id: G8QXN9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15425
gene id: 158190:SPIGRAPES_RS15425
uniprot id: G8QYZ0
names: Similarity
messages: Belongs to the CdaR family.

158190:SPIGRAPES RS13285
gene id: 158190:SPIGRAPES_RS13285
uniprot id: G8QVB0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

158190:SPIGRAPES RS11365
gene id: 158190:SPIGRAPES_RS11365
uniprot id: G8QSC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS10605
gene id: 158190:SPIGRAPES_RS10605
uniprot id: G8QRI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

158190:SPIGRAPES RS10395
gene id: 158190:SPIGRAPES_RS10395
uniprot id: G8QR25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

158190:SPIGRAPES RS10690
gene id: 158190:SPIGRAPES_RS10690
uniprot id: G8QRJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

158190:SPIGRAPES RS04990
gene id: 158190:SPIGRAPES_RS04990
uniprot id: G8QRP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

158190:SPIGRAPES RS05975
gene id: 158190:SPIGRAPES_RS05975
uniprot id: G8QSR1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

158190:SPIGRAPES RS12315
gene id: 158190:SPIGRAPES_RS12315
uniprot id: G8QTJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

158190:SPIGRAPES RS09275
gene id: 158190:SPIGRAPES_RS09275
uniprot id: G8QY96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

158190:SPIGRAPES RS03570
gene id: 158190:SPIGRAPES_RS03570
uniprot id: G8QYK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS06015
gene id: 158190:SPIGRAPES_RS06015
uniprot id: G8QT63
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

158190:SPIGRAPES RS16480
gene id: 158190:SPIGRAPES_RS16480
uniprot id: G8QS85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

158190:SPIGRAPES RS14645
gene id: 158190:SPIGRAPES_RS14645
uniprot id: G8QXQ1
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS07400
gene id: 158190:SPIGRAPES_RS07400
uniprot id: G8QV66
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

158190:SPIGRAPES RS08870
gene id: 158190:SPIGRAPES_RS08870
uniprot id: G8QXL8
names: Similarity
messages: Belongs to the asparagine synthetase family.

158190:SPIGRAPES RS04255
gene id: 158190:SPIGRAPES_RS04255
uniprot id: G8QQQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

158190:SPIGRAPES RS15840
gene id: 158190:SPIGRAPES_RS15840
uniprot id: G8QQK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

158190:SPIGRAPES RS09515
gene id: 158190:SPIGRAPES_RS09515
uniprot id: G8QYT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

158190:SPIGRAPES RS06815
gene id: 158190:SPIGRAPES_RS06815
uniprot id: G8QUF1
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS01975
gene id: 158190:SPIGRAPES_RS01975
uniprot id: G8QW13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

158190:SPIGRAPES RS14780
gene id: 158190:SPIGRAPES_RS14780
uniprot id: G8QXS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

158190:SPIGRAPES RS04725
gene id: 158190:SPIGRAPES_RS04725
uniprot id: G8QRC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

158190:SPIGRAPES RS11400
gene id: 158190:SPIGRAPES_RS11400
uniprot id: G8QSD5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

158190:SPIGRAPES RS08275
gene id: 158190:SPIGRAPES_RS08275
uniprot id: G8QWW3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

158190:SPIGRAPES RS06940
gene id: 158190:SPIGRAPES_RS06940
uniprot id: G8QUH6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

158190:SPIGRAPES RS05650
gene id: 158190:SPIGRAPES_RS05650
uniprot id: G8QSJ9
names: Similarity
messages: Belongs to the CobT family.

158190:SPIGRAPES RS11430
gene id: 158190:SPIGRAPES_RS11430
uniprot id: G8QSE1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

158190:SPIGRAPES RS02450
gene id: 158190:SPIGRAPES_RS02450
uniprot id: G8QWQ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

158190:SPIGRAPES RS05685
gene id: 158190:SPIGRAPES_RS05685
uniprot id: G8QSK6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS02550
gene id: 158190:SPIGRAPES_RS02550
uniprot id: G8QWS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS03255
gene id: 158190:SPIGRAPES_RS03255
uniprot id: G8QXZ5
names: Similarity
messages: Belongs to the FemABX family.

158190:SPIGRAPES RS13905
gene id: 158190:SPIGRAPES_RS13905
uniprot id: G8QWG9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS03305
gene id: 158190:SPIGRAPES_RS03305
uniprot id: G8QY05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS15035
gene id: 158190:SPIGRAPES_RS15035
uniprot id: G8QYC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

158190:SPIGRAPES RS07835
gene id: 158190:SPIGRAPES_RS07835
uniprot id: G8QW87
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS13245
gene id: 158190:SPIGRAPES_RS13245
uniprot id: G8QVA2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

158190:SPIGRAPES RS01160
gene id: 158190:SPIGRAPES_RS01160
uniprot id: G8QUC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS13155
gene id: 158190:SPIGRAPES_RS13155
uniprot id: G8QV84
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS01520
gene id: 158190:SPIGRAPES_RS01520
uniprot id: G8QUZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

158190:SPIGRAPES RS04085
gene id: 158190:SPIGRAPES_RS04085
uniprot id: G8QQ76
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

158190:SPIGRAPES RS13900
gene id: 158190:SPIGRAPES_RS13900
uniprot id: G8QWG8
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS11740
gene id: 158190:SPIGRAPES_RS11740
uniprot id: G8QSU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS13750
gene id: 158190:SPIGRAPES_RS13750
uniprot id: G8QVZ1
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

158190:SPIGRAPES RS00720
gene id: 158190:SPIGRAPES_RS00720
uniprot id: G8QTP6
names: Similarity
messages: Belongs to the UPF0597 family.

158190:SPIGRAPES RS02800
gene id: 158190:SPIGRAPES_RS02800
uniprot id: G8QXB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS15100
gene id: 158190:SPIGRAPES_RS15100
uniprot id: G8QYD8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

158190:SPIGRAPES RS04805
gene id: 158190:SPIGRAPES_RS04805
uniprot id: G8QRE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS08500
gene id: 158190:SPIGRAPES_RS08500
uniprot id: G8QX05
names: Similarity
messages: Belongs to the TPP enzyme family.

158190:SPIGRAPES RS02855
gene id: 158190:SPIGRAPES_RS02855
uniprot id: G8QXC5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

158190:SPIGRAPES RS07535
gene id: 158190:SPIGRAPES_RS07535
uniprot id: G8QVN5
names: Similarity
messages: Belongs to the DapA family.

158190:SPIGRAPES RS08295
gene id: 158190:SPIGRAPES_RS08295
uniprot id: G8QWW7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

158190:SPIGRAPES RS06170
gene id: 158190:SPIGRAPES_RS06170
uniprot id: G8QT93
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS02095
gene id: 158190:SPIGRAPES_RS02095
uniprot id: G8QW37
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

158190:SPIGRAPES RS16140
gene id: 158190:SPIGRAPES_RS16140
uniprot id: G8QR55
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

158190:SPIGRAPES RS02690
gene id: 158190:SPIGRAPES_RS02690
uniprot id: G8QWV0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

158190:SPIGRAPES RS13075
gene id: 158190:SPIGRAPES_RS13075
uniprot id: G8QUS6
names: Similarity
messages: Belongs to the thioredoxin family.

158190:SPIGRAPES RS05775
gene id: 158190:SPIGRAPES_RS05775
uniprot id: G8QSM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

158190:SPIGRAPES RS10935
gene id: 158190:SPIGRAPES_RS10935
uniprot id: G8QRX3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

158190:SPIGRAPES RS11780
gene id: 158190:SPIGRAPES_RS11780
uniprot id: G8QSV5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

158190:SPIGRAPES RS05465
gene id: 158190:SPIGRAPES_RS05465
uniprot id: G8QS64
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS06905
gene id: 158190:SPIGRAPES_RS06905
uniprot id: G8QUG9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

158190:SPIGRAPES RS06690
gene id: 158190:SPIGRAPES_RS06690
uniprot id: G8QTY5
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

158190:SPIGRAPES RS08305
gene id: 158190:SPIGRAPES_RS08305
uniprot id: G8QWW9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS03135
gene id: 158190:SPIGRAPES_RS03135
uniprot id: G8QXX0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

158190:SPIGRAPES RS01065
gene id: 158190:SPIGRAPES_RS01065
uniprot id: G8QUB0
names: Similarity
messages: Belongs to the group II decarboxylase family.

158190:SPIGRAPES RS11370
gene id: 158190:SPIGRAPES_RS11370
uniprot id: G8QSC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS02040
gene id: 158190:SPIGRAPES_RS02040
uniprot id: G8QW26
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

158190:SPIGRAPES RS13295
gene id: 158190:SPIGRAPES_RS13295
uniprot id: G8QVB2
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

158190:SPIGRAPES RS16075
gene id: 158190:SPIGRAPES_RS16075
uniprot id: G8QR42
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158190:SPIGRAPES RS15865
gene id: 158190:SPIGRAPES_RS15865
uniprot id: G8QQK6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

158190:SPIGRAPES RS05850
gene id: 158190:SPIGRAPES_RS05850
uniprot id: G8QSN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

158190:SPIGRAPES RS05855
gene id: 158190:SPIGRAPES_RS05855
uniprot id: G8QSN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

158190:SPIGRAPES RS04010
gene id: 158190:SPIGRAPES_RS04010
uniprot id: G8QQ61
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

158190:SPIGRAPES RS12525
gene id: 158190:SPIGRAPES_RS12525
uniprot id: G8QU27
names: Similarity
messages: Belongs to the class-I fumarase family.

158190:SPIGRAPES RS02895
gene id: 158190:SPIGRAPES_RS02895
uniprot id: G8QXD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

158190:SPIGRAPES RS01905
gene id: 158190:SPIGRAPES_RS01905
uniprot id: G8QVL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

158190:SPIGRAPES RS02080
gene id: 158190:SPIGRAPES_RS02080
uniprot id: G8QW34
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10170
gene id: 158190:SPIGRAPES_RS10170
uniprot id: G8QQY3
names: Similarity
messages: Belongs to the PspA/IM30 family.

158190:SPIGRAPES RS09520
gene id: 158190:SPIGRAPES_RS09520
uniprot id: G8QYT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

158190:SPIGRAPES RS05425
gene id: 158190:SPIGRAPES_RS05425
uniprot id: G8QS56
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

158190:SPIGRAPES RS14620
gene id: 158190:SPIGRAPES_RS14620
uniprot id: G8QXP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

158190:SPIGRAPES RS16225
gene id: 158190:SPIGRAPES_RS16225
uniprot id: G8QR72
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

158190:SPIGRAPES RS02795
gene id: 158190:SPIGRAPES_RS02795
uniprot id: G8QXB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS11395
gene id: 158190:SPIGRAPES_RS11395
uniprot id: G8QSD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

158190:SPIGRAPES RS10595
gene id: 158190:SPIGRAPES_RS10595
uniprot id: G8QRI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

158190:SPIGRAPES RS09475
gene id: 158190:SPIGRAPES_RS09475
uniprot id: G8QYS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS00545
gene id: 158190:SPIGRAPES_RS00545
uniprot id: G8QTL0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

158190:SPIGRAPES RS03970
gene id: 158190:SPIGRAPES_RS03970
uniprot id: G8QQ54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

158190:SPIGRAPES RS03450
gene id: 158190:SPIGRAPES_RS03450
uniprot id: G8QY33
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10260
gene id: 158190:SPIGRAPES_RS10260
uniprot id: G8QQZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

158190:SPIGRAPES RS00460
gene id: 158190:SPIGRAPES_RS00460
uniprot id: G8QT52
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

158190:SPIGRAPES RS13660
gene id: 158190:SPIGRAPES_RS13660
uniprot id: G8QVX3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

158190:SPIGRAPES RS03075
gene id: 158190:SPIGRAPES_RS03075
uniprot id: G8QXG2
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS16125
gene id: 158190:SPIGRAPES_RS16125
uniprot id: G8QR52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

158190:SPIGRAPES RS10515
gene id: 158190:SPIGRAPES_RS10515
uniprot id: G8QRG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

158190:SPIGRAPES RS01805
gene id: 158190:SPIGRAPES_RS01805
uniprot id: G8QVJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

158190:SPIGRAPES RS01995
gene id: 158190:SPIGRAPES_RS01995
uniprot id: G8QW17
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

158190:SPIGRAPES RS06615
gene id: 158190:SPIGRAPES_RS06615
uniprot id: G8QTW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS07020
gene id: 158190:SPIGRAPES_RS07020
uniprot id: G8QUJ2
names: Similarity
messages: Belongs to the FGGY kinase family.

158190:SPIGRAPES RS06550
gene id: 158190:SPIGRAPES_RS06550
uniprot id: G8QTV6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

158190:SPIGRAPES RS00970
gene id: 158190:SPIGRAPES_RS00970
uniprot id: G8QU91
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

158190:SPIGRAPES RS13025
gene id: 158190:SPIGRAPES_RS13025
uniprot id: G8QUR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS13825
gene id: 158190:SPIGRAPES_RS13825
uniprot id: G8QW05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

158190:SPIGRAPES RS04140
gene id: 158190:SPIGRAPES_RS04140
uniprot id: G8QQ87
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

158190:SPIGRAPES RS01740
gene id: 158190:SPIGRAPES_RS01740
uniprot id: G8QVH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

158190:SPIGRAPES RS02545
gene id: 158190:SPIGRAPES_RS02545
uniprot id: G8QWS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS01715
gene id: 158190:SPIGRAPES_RS01715
uniprot id: G8QVH2
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS03750
gene id: 158190:SPIGRAPES_RS03750
uniprot id: G8QYN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

158190:SPIGRAPES RS07350
gene id: 158190:SPIGRAPES_RS07350
uniprot id: G8QV56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS07265
gene id: 158190:SPIGRAPES_RS07265
uniprot id: G8QV38
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

158190:SPIGRAPES RS15475
gene id: 158190:SPIGRAPES_RS15475
uniprot id: G8QZ00
names: Similarity
messages: Belongs to the creatininase superfamily.

158190:SPIGRAPES RS05620
gene id: 158190:SPIGRAPES_RS05620
uniprot id: G8QS93
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

158190:SPIGRAPES RS15055
gene id: 158190:SPIGRAPES_RS15055
uniprot id: G8QYC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

158190:SPIGRAPES RS09395
gene id: 158190:SPIGRAPES_RS09395
uniprot id: G8QYQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

158190:SPIGRAPES RS03805
gene id: 158190:SPIGRAPES_RS03805
uniprot id: G8QYP2
names: Similarity
messages: Belongs to the type IA topoisomerase family.

158190:SPIGRAPES RS05390
gene id: 158190:SPIGRAPES_RS05390
uniprot id: G8QS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

158190:SPIGRAPES RS08885
gene id: 158190:SPIGRAPES_RS08885
uniprot id: G8QXM1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

158190:SPIGRAPES RS10285
gene id: 158190:SPIGRAPES_RS10285
uniprot id: G8QR03
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

158190:SPIGRAPES RS10725
gene id: 158190:SPIGRAPES_RS10725
uniprot id: G8QRK6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

158190:SPIGRAPES RS06105
gene id: 158190:SPIGRAPES_RS06105
uniprot id: G8QT80
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

158190:SPIGRAPES RS02620
gene id: 158190:SPIGRAPES_RS02620
uniprot id: G8QWT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

158190:SPIGRAPES RS06140
gene id: 158190:SPIGRAPES_RS06140
uniprot id: G8QT87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

158190:SPIGRAPES RS16355
gene id: 158190:SPIGRAPES_RS16355
uniprot id: G8QT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS02915
gene id: 158190:SPIGRAPES_RS02915
uniprot id: G8QXD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS09760
gene id: 158190:SPIGRAPES_RS09760
uniprot id: G8QQA4
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

158190:SPIGRAPES RS06540
gene id: 158190:SPIGRAPES_RS06540
uniprot id: G8QTV4
names: Similarity
messages: Belongs to the DapA family.

158190:SPIGRAPES RS11070
gene id: 158190:SPIGRAPES_RS11070
uniprot id: G8QS00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

158190:SPIGRAPES RS14905
gene id: 158190:SPIGRAPES_RS14905
uniprot id: G8QXV3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

158190:SPIGRAPES RS03350
gene id: 158190:SPIGRAPES_RS03350
uniprot id: G8QY13
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

158190:SPIGRAPES RS06205
gene id: 158190:SPIGRAPES_RS06205
uniprot id: G8QT97
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

158190:SPIGRAPES RS12845
gene id: 158190:SPIGRAPES_RS12845
uniprot id: G8QUN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

158190:SPIGRAPES RS15815
gene id: 158190:SPIGRAPES_RS15815
uniprot id: G8QQJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS10215
gene id: 158190:SPIGRAPES_RS10215
uniprot id: G8QQZ0
names: Similarity
messages: Belongs to the PspA/IM30 family.

158190:SPIGRAPES RS15470
gene id: 158190:SPIGRAPES_RS15470
uniprot id: G8QYZ9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

158190:SPIGRAPES RS08970
gene id: 158190:SPIGRAPES_RS08970
uniprot id: G8QY36
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS07370
gene id: 158190:SPIGRAPES_RS07370
uniprot id: G8QV60
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS12335
gene id: 158190:SPIGRAPES_RS12335
uniprot id: G8QTJ5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

158190:SPIGRAPES RS07190
gene id: 158190:SPIGRAPES_RS07190
uniprot id: G8QV23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS08495
gene id: 158190:SPIGRAPES_RS08495
uniprot id: G8QX04
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS01445
gene id: 158190:SPIGRAPES_RS01445
uniprot id: G8QUX7
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

158190:SPIGRAPES RS00170
gene id: 158190:SPIGRAPES_RS00170
uniprot id: G8QSZ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

158190:SPIGRAPES RS12920
gene id: 158190:SPIGRAPES_RS12920
uniprot id: G8QUP5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

158190:SPIGRAPES RS01710
gene id: 158190:SPIGRAPES_RS01710
uniprot id: G8QVH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

158190:SPIGRAPES RS05360
gene id: 158190:SPIGRAPES_RS05360
uniprot id: G8QS43
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS06310
gene id: 158190:SPIGRAPES_RS06310
uniprot id: G8QTB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

158190:SPIGRAPES RS05535
gene id: 158190:SPIGRAPES_RS05535
uniprot id: G8QS76
names: Similarity
messages: Belongs to the SecB family.

158190:SPIGRAPES RS03550
gene id: 158190:SPIGRAPES_RS03550
uniprot id: G8QYJ6
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10400
gene id: 158190:SPIGRAPES_RS10400
uniprot id: G8QR26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

158190:SPIGRAPES RS14750
gene id: 158190:SPIGRAPES_RS14750
uniprot id: G8QXS2
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

158190:SPIGRAPES RS03090
gene id: 158190:SPIGRAPES_RS03090
uniprot id: G8QXW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

158190:SPIGRAPES RS00445
gene id: 158190:SPIGRAPES_RS00445
uniprot id: G8QT49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS02470
gene id: 158190:SPIGRAPES_RS02470
uniprot id: G8QWR0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

158190:SPIGRAPES RS02430
gene id: 158190:SPIGRAPES_RS02430
uniprot id: G8QWQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

158190:SPIGRAPES RS07480
gene id: 158190:SPIGRAPES_RS07480
uniprot id: G8QVM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS05000
gene id: 158190:SPIGRAPES_RS05000
uniprot id: G8QRP9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS12330
gene id: 158190:SPIGRAPES_RS12330
uniprot id: G8QTJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

158190:SPIGRAPES RS07385
gene id: 158190:SPIGRAPES_RS07385
uniprot id: G8QV63
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

158190:SPIGRAPES RS13665
gene id: 158190:SPIGRAPES_RS13665
uniprot id: G8QVX4
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

158190:SPIGRAPES RS02440
gene id: 158190:SPIGRAPES_RS02440
uniprot id: G8QWQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

158190:SPIGRAPES RS09150
gene id: 158190:SPIGRAPES_RS09150
uniprot id: G8QY71
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

158190:SPIGRAPES RS00555
gene id: 158190:SPIGRAPES_RS00555
uniprot id: G8QTL2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

158190:SPIGRAPES RS01700
gene id: 158190:SPIGRAPES_RS01700
uniprot id: G8QVG9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

158190:SPIGRAPES RS01970
gene id: 158190:SPIGRAPES_RS01970
uniprot id: G8QW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

158190:SPIGRAPES RS08935
gene id: 158190:SPIGRAPES_RS08935
uniprot id: G8QXN1
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

158190:SPIGRAPES RS07030
gene id: 158190:SPIGRAPES_RS07030
uniprot id: G8QUJ4
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10645
gene id: 158190:SPIGRAPES_RS10645
uniprot id: G8QRJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

158190:SPIGRAPES RS12765
gene id: 158190:SPIGRAPES_RS12765
uniprot id: G8QUL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

158190:SPIGRAPES RS07035
gene id: 158190:SPIGRAPES_RS07035
uniprot id: G8QUJ5
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS09650
gene id: 158190:SPIGRAPES_RS09650
uniprot id: G8QYV5
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

158190:SPIGRAPES RS04795
gene id: 158190:SPIGRAPES_RS04795
uniprot id: G8QRE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

158190:SPIGRAPES RS09245
gene id: 158190:SPIGRAPES_RS09245
uniprot id: G8QY90
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

158190:SPIGRAPES RS11495
gene id: 158190:SPIGRAPES_RS11495
uniprot id: G8QSF1
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

158190:SPIGRAPES RS02370
gene id: 158190:SPIGRAPES_RS02370
uniprot id: G8QWN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

158190:SPIGRAPES RS15020
gene id: 158190:SPIGRAPES_RS15020
uniprot id: G8QYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

158190:SPIGRAPES RS05690
gene id: 158190:SPIGRAPES_RS05690
uniprot id: G8QSK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS04115
gene id: 158190:SPIGRAPES_RS04115
uniprot id: G8QQ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS04370
gene id: 158190:SPIGRAPES_RS04370
uniprot id: G8QQS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

158190:SPIGRAPES RS09495
gene id: 158190:SPIGRAPES_RS09495
uniprot id: G8QYS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

158190:SPIGRAPES RS02180
gene id: 158190:SPIGRAPES_RS02180
uniprot id: G8QW54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS12220
gene id: 158190:SPIGRAPES_RS12220
uniprot id: G8QTH3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

158190:SPIGRAPES RS00485
gene id: 158190:SPIGRAPES_RS00485
uniprot id: G8QT58
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS02210
gene id: 158190:SPIGRAPES_RS02210
uniprot id: G8QW60
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

158190:SPIGRAPES RS10390
gene id: 158190:SPIGRAPES_RS10390
uniprot id: G8QR24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

158190:SPIGRAPES RS02035
gene id: 158190:SPIGRAPES_RS02035
uniprot id: G8QW25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

158190:SPIGRAPES RS04825
gene id: 158190:SPIGRAPES_RS04825
uniprot id: G8QRE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

158190:SPIGRAPES RS07910
gene id: 158190:SPIGRAPES_RS07910
uniprot id: G8QWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS15820
gene id: 158190:SPIGRAPES_RS15820
uniprot id: G8QQJ7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

158190:SPIGRAPES RS01550
gene id: 158190:SPIGRAPES_RS01550
uniprot id: G8QUZ7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

158190:SPIGRAPES RS05135
gene id: 158190:SPIGRAPES_RS05135
uniprot id: G8QRS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

158190:SPIGRAPES RS01775
gene id: 158190:SPIGRAPES_RS01775
uniprot id: G8QVI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

158190:SPIGRAPES RS12685
gene id: 158190:SPIGRAPES_RS12685
uniprot id: G8QU59
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS03555
gene id: 158190:SPIGRAPES_RS03555
uniprot id: G8QYJ7
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS14570
gene id: 158190:SPIGRAPES_RS14570
uniprot id: G8QXN6
names: Similarity
messages: Belongs to the UPF0047 family.

158190:SPIGRAPES RS10680
gene id: 158190:SPIGRAPES_RS10680
uniprot id: G8QRJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

158190:SPIGRAPES RS07915
gene id: 158190:SPIGRAPES_RS07915
uniprot id: G8QWA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS05805
gene id: 158190:SPIGRAPES_RS05805
uniprot id: G8QSM7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

158190:SPIGRAPES RS12490
gene id: 158190:SPIGRAPES_RS12490
uniprot id: G8QU20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

158190:SPIGRAPES RS04240
gene id: 158190:SPIGRAPES_RS04240
uniprot id: G8QQQ4
names: Similarity
messages: Belongs to the peptidase C1 family.

158190:SPIGRAPES RS10520
gene id: 158190:SPIGRAPES_RS10520
uniprot id: G8QRG7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

158190:SPIGRAPES RS03290
gene id: 158190:SPIGRAPES_RS03290
uniprot id: G8QY02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

158190:SPIGRAPES RS13070
gene id: 158190:SPIGRAPES_RS13070
uniprot id: G8QUS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

158190:SPIGRAPES RS03965
gene id: 158190:SPIGRAPES_RS03965
uniprot id: G8QQ53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

158190:SPIGRAPES RS13565
gene id: 158190:SPIGRAPES_RS13565
uniprot id: G8QVV4
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS07950
gene id: 158190:SPIGRAPES_RS07950
uniprot id: G8QWB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

158190:SPIGRAPES RS05225
gene id: 158190:SPIGRAPES_RS05225
uniprot id: G8QRU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS00140
gene id: 158190:SPIGRAPES_RS00140
uniprot id: G8QSJ5
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

158190:SPIGRAPES RS08750
gene id: 158190:SPIGRAPES_RS08750
uniprot id: G8QXJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS09680
gene id: 158190:SPIGRAPES_RS09680
uniprot id: G8QYW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

158190:SPIGRAPES RS11135
gene id: 158190:SPIGRAPES_RS11135
uniprot id: G8QS13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

158190:SPIGRAPES RS15300
gene id: 158190:SPIGRAPES_RS15300
uniprot id: G8QYW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

158190:SPIGRAPES RS10710
gene id: 158190:SPIGRAPES_RS10710
uniprot id: G8QRK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

158190:SPIGRAPES RS09545
gene id: 158190:SPIGRAPES_RS09545
uniprot id: G8QYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

158190:SPIGRAPES RS02065
gene id: 158190:SPIGRAPES_RS02065
uniprot id: G8QW31
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS13595
gene id: 158190:SPIGRAPES_RS13595
uniprot id: G8QVW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

158190:SPIGRAPES RS04135
gene id: 158190:SPIGRAPES_RS04135
uniprot id: G8QQ86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

158190:SPIGRAPES RS15925
gene id: 158190:SPIGRAPES_RS15925
uniprot id: G8QQL8
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS07355
gene id: 158190:SPIGRAPES_RS07355
uniprot id: G8QV57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS03780
gene id: 158190:SPIGRAPES_RS03780
uniprot id: G8QYN7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

158190:SPIGRAPES RS07515
gene id: 158190:SPIGRAPES_RS07515
uniprot id: G8QVN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS03225
gene id: 158190:SPIGRAPES_RS03225
uniprot id: G8QXY8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

158190:SPIGRAPES RS03650
gene id: 158190:SPIGRAPES_RS03650
uniprot id: G8QYL2
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

158190:SPIGRAPES RS10695
gene id: 158190:SPIGRAPES_RS10695
uniprot id: G8QRK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

158190:SPIGRAPES RS01650
gene id: 158190:SPIGRAPES_RS01650
uniprot id: G8QVF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

158190:SPIGRAPES RS04745
gene id: 158190:SPIGRAPES_RS04745
uniprot id: G8QRD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS04840
gene id: 158190:SPIGRAPES_RS04840
uniprot id: G8QRF1
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS11415
gene id: 158190:SPIGRAPES_RS11415
uniprot id: G8QSD8
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10900
gene id: 158190:SPIGRAPES_RS10900
uniprot id: G8QRW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

158190:SPIGRAPES RS14210
gene id: 158190:SPIGRAPES_RS14210
uniprot id: G8QX22
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

158190:SPIGRAPES RS02590
gene id: 158190:SPIGRAPES_RS02590
uniprot id: G8QWT3
names: Similarity
messages: Belongs to the peptidase M29 family.

158190:SPIGRAPES RS02290
gene id: 158190:SPIGRAPES_RS02290
uniprot id: G8QW74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

158190:SPIGRAPES RS01655
gene id: 158190:SPIGRAPES_RS01655
uniprot id: G8QVG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

158190:SPIGRAPES RS08980
gene id: 158190:SPIGRAPES_RS08980
uniprot id: G8QY38
names: Similarity
messages: Belongs to the glutamine synthetase family.

158190:SPIGRAPES RS11790
gene id: 158190:SPIGRAPES_RS11790
uniprot id: G8QSV7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

158190:SPIGRAPES RS12880
gene id: 158190:SPIGRAPES_RS12880
uniprot id: G8QUN7
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS16295
gene id: 158190:SPIGRAPES_RS16295
uniprot id: G8QR86
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

158190:SPIGRAPES RS11465
gene id: 158190:SPIGRAPES_RS11465
uniprot id: G8QSE7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

158190:SPIGRAPES RS04965
gene id: 158190:SPIGRAPES_RS04965
uniprot id: G8QRP4
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS08655
gene id: 158190:SPIGRAPES_RS08655
uniprot id: G8QXH6
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS12710
gene id: 158190:SPIGRAPES_RS12710
uniprot id: G8QU64
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

158190:SPIGRAPES RS05670
gene id: 158190:SPIGRAPES_RS05670
uniprot id: G8QSK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

158190:SPIGRAPES RS10085
gene id: 158190:SPIGRAPES_RS10085
uniprot id: G8QQW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

158190:SPIGRAPES RS10630
gene id: 158190:SPIGRAPES_RS10630
uniprot id: G8QRI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

158190:SPIGRAPES RS00620
gene id: 158190:SPIGRAPES_RS00620
uniprot id: G8QTM6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS06455
gene id: 158190:SPIGRAPES_RS06455
uniprot id: G8QTT7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

158190:SPIGRAPES RS14810
gene id: 158190:SPIGRAPES_RS14810
uniprot id: G8QXT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

158190:SPIGRAPES RS03270
gene id: 158190:SPIGRAPES_RS03270
uniprot id: G8QXZ8
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

158190:SPIGRAPES RS10700
gene id: 158190:SPIGRAPES_RS10700
uniprot id: G8QRK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

158190:SPIGRAPES RS04265
gene id: 158190:SPIGRAPES_RS04265
uniprot id: G8QQQ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS03310
gene id: 158190:SPIGRAPES_RS03310
uniprot id: G8QY06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS09205
gene id: 158190:SPIGRAPES_RS09205
uniprot id: G8QY82
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS14775
gene id: 158190:SPIGRAPES_RS14775
uniprot id: G8QXS7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

158190:SPIGRAPES RS12130
gene id: 158190:SPIGRAPES_RS12130
uniprot id: G8QTF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

158190:SPIGRAPES RS00180
gene id: 158190:SPIGRAPES_RS00180
uniprot id: G8QSZ7
names: Similarity
messages: Belongs to the threonine synthase family.

158190:SPIGRAPES RS14600
gene id: 158190:SPIGRAPES_RS14600
uniprot id: G8QXP2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

158190:SPIGRAPES RS04170
gene id: 158190:SPIGRAPES_RS04170
uniprot id: G8QQ93
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

158190:SPIGRAPES RS04655
gene id: 158190:SPIGRAPES_RS04655
uniprot id: G8QRB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS08680
gene id: 158190:SPIGRAPES_RS08680
uniprot id: G8QXI1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

158190:SPIGRAPES RS02425
gene id: 158190:SPIGRAPES_RS02425
uniprot id: G8QWQ0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

158190:SPIGRAPES RS07815
gene id: 158190:SPIGRAPES_RS07815
uniprot id: G8QW83
names: Similarity
messages: Belongs to the CapA family.

158190:SPIGRAPES RS00425
gene id: 158190:SPIGRAPES_RS00425
uniprot id: G8QT45
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

158190:SPIGRAPES RS03200
gene id: 158190:SPIGRAPES_RS03200
uniprot id: G8QXY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

158190:SPIGRAPES RS13600
gene id: 158190:SPIGRAPES_RS13600
uniprot id: G8QVW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

158190:SPIGRAPES RS00960
gene id: 158190:SPIGRAPES_RS00960
uniprot id: G8QU89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

158190:SPIGRAPES RS01265
gene id: 158190:SPIGRAPES_RS01265
uniprot id: G8QUU3
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

158190:SPIGRAPES RS02700
gene id: 158190:SPIGRAPES_RS02700
uniprot id: G8QX95
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

158190:SPIGRAPES RS05340
gene id: 158190:SPIGRAPES_RS05340
uniprot id: G8QS39
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS00440
gene id: 158190:SPIGRAPES_RS00440
uniprot id: G8QT48
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

158190:SPIGRAPES RS02205
gene id: 158190:SPIGRAPES_RS02205
uniprot id: G8QW59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

158190:SPIGRAPES RS00085
gene id: 158190:SPIGRAPES_RS00085
uniprot id: G8QSI6
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS00580
gene id: 158190:SPIGRAPES_RS00580
uniprot id: G8QTL8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

158190:SPIGRAPES RS07680
gene id: 158190:SPIGRAPES_RS07680
uniprot id: G8QVR4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

158190:SPIGRAPES RS16345
gene id: 158190:SPIGRAPES_RS16345
uniprot id: G8QSH5
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS09570
gene id: 158190:SPIGRAPES_RS09570
uniprot id: G8QYU3
names: Similarity
messages: Belongs to the ParB family.

158190:SPIGRAPES RS02310
gene id: 158190:SPIGRAPES_RS02310
uniprot id: G8QW78
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

158190:SPIGRAPES RS14945
gene id: 158190:SPIGRAPES_RS14945
uniprot id: G8QYA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

158190:SPIGRAPES RS13615
gene id: 158190:SPIGRAPES_RS13615
uniprot id: G8QVW4
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

158190:SPIGRAPES RS07430
gene id: 158190:SPIGRAPES_RS07430
uniprot id: G8QV70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

158190:SPIGRAPES RS15305
gene id: 158190:SPIGRAPES_RS15305
uniprot id: G8QYW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

158190:SPIGRAPES RS06395
gene id: 158190:SPIGRAPES_RS06395
uniprot id: G8QTS4
names: Similarity
messages: Belongs to the UPF0758 family.

158190:SPIGRAPES RS05010
gene id: 158190:SPIGRAPES_RS05010
uniprot id: G8QRQ1
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS13060
gene id: 158190:SPIGRAPES_RS13060
uniprot id: G8QUS3
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10340
gene id: 158190:SPIGRAPES_RS10340
uniprot id: G8QR14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

158190:SPIGRAPES RS06095
gene id: 158190:SPIGRAPES_RS06095
uniprot id: G8QT78
names: Similarity
messages: Belongs to the sigma-54 factor family.

158190:SPIGRAPES RS16030
gene id: 158190:SPIGRAPES_RS16030
uniprot id: G8QQN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

158190:SPIGRAPES RS14560
gene id: 158190:SPIGRAPES_RS14560
uniprot id: G8QX93
names: Similarity
messages: Belongs to the arginase family.

158190:SPIGRAPES RS16175
gene id: 158190:SPIGRAPES_RS16175
uniprot id: G8QR62
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

158190:SPIGRAPES RS02270
gene id: 158190:SPIGRAPES_RS02270
uniprot id: G8QW70
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10765
gene id: 158190:SPIGRAPES_RS10765
uniprot id: G8QRL5
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

158190:SPIGRAPES RS00730
gene id: 158190:SPIGRAPES_RS00730
uniprot id: G8QTP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS09315
gene id: 158190:SPIGRAPES_RS09315
uniprot id: G8QYA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS07395
gene id: 158190:SPIGRAPES_RS07395
uniprot id: G8QV65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

158190:SPIGRAPES RS10875
gene id: 158190:SPIGRAPES_RS10875
uniprot id: G8QRW1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

158190:SPIGRAPES RS14865
gene id: 158190:SPIGRAPES_RS14865
uniprot id: G8QXU5
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15380
gene id: 158190:SPIGRAPES_RS15380
uniprot id: G8QYY0
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

158190:SPIGRAPES RS00830
gene id: 158190:SPIGRAPES_RS00830
uniprot id: G8QTR8
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS04335
gene id: 158190:SPIGRAPES_RS04335
uniprot id: G8QQS3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

158190:SPIGRAPES RS16025
gene id: 158190:SPIGRAPES_RS16025
uniprot id: G8QQN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

158190:SPIGRAPES RS15910
gene id: 158190:SPIGRAPES_RS15910
uniprot id: G8QQL5
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

158190:SPIGRAPES RS09210
gene id: 158190:SPIGRAPES_RS09210
uniprot id: G8QY83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

158190:SPIGRAPES RS12730
gene id: 158190:SPIGRAPES_RS12730
uniprot id: G8QUK7
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

158190:SPIGRAPES RS02740
gene id: 158190:SPIGRAPES_RS02740
uniprot id: G8QXA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

158190:SPIGRAPES RS02570
gene id: 158190:SPIGRAPES_RS02570
uniprot id: G8QWS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

158190:SPIGRAPES RS07565
gene id: 158190:SPIGRAPES_RS07565
uniprot id: G8QVP1
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

158190:SPIGRAPES RS05210
gene id: 158190:SPIGRAPES_RS05210
uniprot id: G8QRU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

158190:SPIGRAPES RS06525
gene id: 158190:SPIGRAPES_RS06525
uniprot id: G8QTV1
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS02600
gene id: 158190:SPIGRAPES_RS02600
uniprot id: G8QWT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS15985
gene id: 158190:SPIGRAPES_RS15985
uniprot id: G8QQM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

158190:SPIGRAPES RS13195
gene id: 158190:SPIGRAPES_RS13195
uniprot id: G8QV92
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

158190:SPIGRAPES RS11775
gene id: 158190:SPIGRAPES_RS11775
uniprot id: G8QSV4
names: Similarity
messages: Belongs to the FGGY kinase family.

158190:SPIGRAPES RS02320
gene id: 158190:SPIGRAPES_RS02320
uniprot id: G8QW80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

158190:SPIGRAPES RS11580
gene id: 158190:SPIGRAPES_RS11580
uniprot id: G8QSG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

158190:SPIGRAPES RS08650
gene id: 158190:SPIGRAPES_RS08650
uniprot id: G8QXH5
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10575
gene id: 158190:SPIGRAPES_RS10575
uniprot id: G8QRH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

158190:SPIGRAPES RS16510
gene id: 158190:SPIGRAPES_RS16510
uniprot id: G8QUG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

158190:SPIGRAPES RS05870
gene id: 158190:SPIGRAPES_RS05870
uniprot id: G8QSP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

158190:SPIGRAPES RS09445
gene id: 158190:SPIGRAPES_RS09445
uniprot id: G8QYR8
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

158190:SPIGRAPES RS09195
gene id: 158190:SPIGRAPES_RS09195
uniprot id: G8QY80
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS05275
gene id: 158190:SPIGRAPES_RS05275
uniprot id: G8QRV5
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS14975
gene id: 158190:SPIGRAPES_RS14975
uniprot id: G8QYB4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

158190:SPIGRAPES RS02075
gene id: 158190:SPIGRAPES_RS02075
uniprot id: G8QW33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

158190:SPIGRAPES RS10150
gene id: 158190:SPIGRAPES_RS10150
uniprot id: G8QQX9
names: Similarity
messages: Belongs to the CarB family.

158190:SPIGRAPES RS13420
gene id: 158190:SPIGRAPES_RS13420
uniprot id: G8QVD6
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS00310
gene id: 158190:SPIGRAPES_RS00310
uniprot id: G8QT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS03250
gene id: 158190:SPIGRAPES_RS03250
uniprot id: G8QXZ4
names: Subcellular Location Annotation
messages: Cytoplasm

158190:SPIGRAPES RS02025
gene id: 158190:SPIGRAPES_RS02025
uniprot id: G8QW23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

158190:SPIGRAPES RS08395
gene id: 158190:SPIGRAPES_RS08395
uniprot id: G8QWY5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

158190:SPIGRAPES RS12310
gene id: 158190:SPIGRAPES_RS12310
uniprot id: G8QTJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

158190:SPIGRAPES RS10445
gene id: 158190:SPIGRAPES_RS10445
uniprot id: G8QR35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

158190:SPIGRAPES RS15070
gene id: 158190:SPIGRAPES_RS15070
uniprot id: G8QYD2
names: Similarity
messages: Belongs to the xylose isomerase family.

158190:SPIGRAPES RS10315
gene id: 158190:SPIGRAPES_RS10315
uniprot id: G8QR09
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

158190:SPIGRAPES RS00515
gene id: 158190:SPIGRAPES_RS00515
uniprot id: G8QTK4
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15895
gene id: 158190:SPIGRAPES_RS15895
uniprot id: G8QQL2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

158190:SPIGRAPES RS00900
gene id: 158190:SPIGRAPES_RS00900
uniprot id: G8QU77
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS02330
gene id: 158190:SPIGRAPES_RS02330
uniprot id: G8QWN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

158190:SPIGRAPES RS15260
gene id: 158190:SPIGRAPES_RS15260
uniprot id: G8QYG8
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

158190:SPIGRAPES RS04475
gene id: 158190:SPIGRAPES_RS04475
uniprot id: G8QQV0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

158190:SPIGRAPES RS16150
gene id: 158190:SPIGRAPES_RS16150
uniprot id: G8QR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS10840
gene id: 158190:SPIGRAPES_RS10840
uniprot id: G8QRN0
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS11130
gene id: 158190:SPIGRAPES_RS11130
uniprot id: G8QS12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS13710
gene id: 158190:SPIGRAPES_RS13710
uniprot id: G8QVY3
names: Similarity
messages: Belongs to the hexokinase family.

158190:SPIGRAPES RS01545
gene id: 158190:SPIGRAPES_RS01545
uniprot id: G8QUZ6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

158190:SPIGRAPES RS13985
gene id: 158190:SPIGRAPES_RS13985
uniprot id: G8QWI6
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

158190:SPIGRAPES RS15830
gene id: 158190:SPIGRAPES_RS15830
uniprot id: G8QQJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

158190:SPIGRAPES RS13050
gene id: 158190:SPIGRAPES_RS13050
uniprot id: G8QUS1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

158190:SPIGRAPES RS00315
gene id: 158190:SPIGRAPES_RS00315
uniprot id: G8QT23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS13275
gene id: 158190:SPIGRAPES_RS13275
uniprot id: G8QVA8
names: Similarity
messages: Belongs to the GARS family.

158190:SPIGRAPES RS14800
gene id: 158190:SPIGRAPES_RS14800
uniprot id: G8QXT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

158190:SPIGRAPES RS10745
gene id: 158190:SPIGRAPES_RS10745
uniprot id: G8QRL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

158190:SPIGRAPES RS04390
gene id: 158190:SPIGRAPES_RS04390
uniprot id: G8QQT3
names: Similarity
messages: Belongs to the TrpC family.

158190:SPIGRAPES RS08820
gene id: 158190:SPIGRAPES_RS08820
uniprot id: G8QXK8
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS04685
gene id: 158190:SPIGRAPES_RS04685
uniprot id: G8QRC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS09865
gene id: 158190:SPIGRAPES_RS09865
uniprot id: G8QQC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS12905
gene id: 158190:SPIGRAPES_RS12905
uniprot id: G8QUP2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

158190:SPIGRAPES RS04130
gene id: 158190:SPIGRAPES_RS04130
uniprot id: G8QQ85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

158190:SPIGRAPES RS02030
gene id: 158190:SPIGRAPES_RS02030
uniprot id: G8QW24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

158190:SPIGRAPES RS06125
gene id: 158190:SPIGRAPES_RS06125
uniprot id: G8QT84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

158190:SPIGRAPES RS15025
gene id: 158190:SPIGRAPES_RS15025
uniprot id: G8QYC3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

158190:SPIGRAPES RS09540
gene id: 158190:SPIGRAPES_RS09540
uniprot id: G8QYT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

158190:SPIGRAPES RS16155
gene id: 158190:SPIGRAPES_RS16155
uniprot id: G8QR58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS08800
gene id: 158190:SPIGRAPES_RS08800
uniprot id: G8QXK4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

158190:SPIGRAPES RS13875
gene id: 158190:SPIGRAPES_RS13875
uniprot id: G8QWG3
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS01770
gene id: 158190:SPIGRAPES_RS01770
uniprot id: G8QVI3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

158190:SPIGRAPES RS15500
gene id: 158190:SPIGRAPES_RS15500
uniprot id: G8QZ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS09730
gene id: 158190:SPIGRAPES_RS09730
uniprot id: G8QQ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

158190:SPIGRAPES RS14500
gene id: 158190:SPIGRAPES_RS14500
uniprot id: G8QX81
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS05910
gene id: 158190:SPIGRAPES_RS05910
uniprot id: G8QSP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

158190:SPIGRAPES RS16505
gene id: 158190:SPIGRAPES_RS16505
uniprot id: G8QTU9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS14265
gene id: 158190:SPIGRAPES_RS14265
uniprot id: G8QX33
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

158190:SPIGRAPES RS14085
gene id: 158190:SPIGRAPES_RS14085
uniprot id: G8QWK5
names: Similarity
messages: Belongs to the peptidase S14 family.

158190:SPIGRAPES RS14635
gene id: 158190:SPIGRAPES_RS14635
uniprot id: G8QXP9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

158190:SPIGRAPES RS01140
gene id: 158190:SPIGRAPES_RS01140
uniprot id: G8QUC4
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15980
gene id: 158190:SPIGRAPES_RS15980
uniprot id: G8QQM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

158190:SPIGRAPES RS13620
gene id: 158190:SPIGRAPES_RS13620
uniprot id: G8QVW5
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

158190:SPIGRAPES RS15395
gene id: 158190:SPIGRAPES_RS15395
uniprot id: G8QYY4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

158190:SPIGRAPES RS14420
gene id: 158190:SPIGRAPES_RS14420
uniprot id: G8QX65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

158190:SPIGRAPES RS02715
gene id: 158190:SPIGRAPES_RS02715
uniprot id: G8QX98
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS09535
gene id: 158190:SPIGRAPES_RS09535
uniprot id: G8QYT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

158190:SPIGRAPES RS16010
gene id: 158190:SPIGRAPES_RS16010
uniprot id: G8QQN4
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

158190:SPIGRAPES RS04385
gene id: 158190:SPIGRAPES_RS04385
uniprot id: G8QQT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS03655
gene id: 158190:SPIGRAPES_RS03655
uniprot id: G8QYL3
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

158190:SPIGRAPES RS14965
gene id: 158190:SPIGRAPES_RS14965
uniprot id: G8QYB2
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

158190:SPIGRAPES RS10760
gene id: 158190:SPIGRAPES_RS10760
uniprot id: G8QRL4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

158190:SPIGRAPES RS14785
gene id: 158190:SPIGRAPES_RS14785
uniprot id: G8QXS9
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

158190:SPIGRAPES RS02685
gene id: 158190:SPIGRAPES_RS02685
uniprot id: G8QWU9
names: Similarity
messages: Belongs to the UxaA family.

158190:SPIGRAPES RS03795
gene id: 158190:SPIGRAPES_RS03795
uniprot id: G8QYP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

158190:SPIGRAPES RS02460
gene id: 158190:SPIGRAPES_RS02460
uniprot id: G8QWQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

158190:SPIGRAPES RS00765
gene id: 158190:SPIGRAPES_RS00765
uniprot id: G8QTQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS03000
gene id: 158190:SPIGRAPES_RS03000
uniprot id: G8QXF3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

158190:SPIGRAPES RS01935
gene id: 158190:SPIGRAPES_RS01935
uniprot id: G8QVL5
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS00480
gene id: 158190:SPIGRAPES_RS00480
uniprot id: G8QT56
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

158190:SPIGRAPES RS10970
gene id: 158190:SPIGRAPES_RS10970
uniprot id: G8QRY0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

158190:SPIGRAPES RS01000
gene id: 158190:SPIGRAPES_RS01000
uniprot id: G8QU97
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

158190:SPIGRAPES RS02660
gene id: 158190:SPIGRAPES_RS02660
uniprot id: G8QWU4
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

158190:SPIGRAPES RS03170
gene id: 158190:SPIGRAPES_RS03170
uniprot id: G8QXX7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS14615
gene id: 158190:SPIGRAPES_RS14615
uniprot id: G8QXP5
names: Similarity
messages: Belongs to the RutC family.

158190:SPIGRAPES RS09675
gene id: 158190:SPIGRAPES_RS09675
uniprot id: G8QYW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

158190:SPIGRAPES RS11615
gene id: 158190:SPIGRAPES_RS11615
uniprot id: G8QSS2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

158190:SPIGRAPES RS04065
gene id: 158190:SPIGRAPES_RS04065
uniprot id: G8QQ72
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

158190:SPIGRAPES RS11225
gene id: 158190:SPIGRAPES_RS11225
uniprot id: G8QS99
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

158190:SPIGRAPES RS03085
gene id: 158190:SPIGRAPES_RS03085
uniprot id: G8QXW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

158190:SPIGRAPES RS08580
gene id: 158190:SPIGRAPES_RS08580
uniprot id: G8QX20
names: Similarity
messages: Belongs to the UPF0597 family.

158190:SPIGRAPES RS08610
gene id: 158190:SPIGRAPES_RS08610
uniprot id: G8QXG7
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10715
gene id: 158190:SPIGRAPES_RS10715
uniprot id: G8QRK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

158190:SPIGRAPES RS09525
gene id: 158190:SPIGRAPES_RS09525
uniprot id: G8QYT4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

158190:SPIGRAPES RS00735
gene id: 158190:SPIGRAPES_RS00735
uniprot id: G8QTP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS13260
gene id: 158190:SPIGRAPES_RS13260
uniprot id: G8QVA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

158190:SPIGRAPES RS05630
gene id: 158190:SPIGRAPES_RS05630
uniprot id: G8QS95
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

158190:SPIGRAPES RS12885
gene id: 158190:SPIGRAPES_RS12885
uniprot id: G8QUN8
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS01990
gene id: 158190:SPIGRAPES_RS01990
uniprot id: G8QW16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

158190:SPIGRAPES RS09965
gene id: 158190:SPIGRAPES_RS09965
uniprot id: G8QQE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

158190:SPIGRAPES RS10705
gene id: 158190:SPIGRAPES_RS10705
uniprot id: G8QRK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

158190:SPIGRAPES RS05845
gene id: 158190:SPIGRAPES_RS05845
uniprot id: G8QSN5
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

158190:SPIGRAPES RS03300
gene id: 158190:SPIGRAPES_RS03300
uniprot id: G8QY04
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

158190:SPIGRAPES RS07675
gene id: 158190:SPIGRAPES_RS07675
uniprot id: G8QVR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS07435
gene id: 158190:SPIGRAPES_RS07435
uniprot id: G8QV71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

158190:SPIGRAPES RS15540
gene id: 158190:SPIGRAPES_RS15540
uniprot id: G8QZ13
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS05065
gene id: 158190:SPIGRAPES_RS05065
uniprot id: G8QRR2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

158190:SPIGRAPES RS10335
gene id: 158190:SPIGRAPES_RS10335
uniprot id: G8QR13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

158190:SPIGRAPES RS03120
gene id: 158190:SPIGRAPES_RS03120
uniprot id: G8QXW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

158190:SPIGRAPES RS03840
gene id: 158190:SPIGRAPES_RS03840
uniprot id: G8QQ35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

158190:SPIGRAPES RS00380
gene id: 158190:SPIGRAPES_RS00380
uniprot id: G8QT36
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

158190:SPIGRAPES RS07620
gene id: 158190:SPIGRAPES_RS07620
uniprot id: G8QVQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS13625
gene id: 158190:SPIGRAPES_RS13625
uniprot id: G8QVW6
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

158190:SPIGRAPES RS06935
gene id: 158190:SPIGRAPES_RS06935
uniprot id: G8QUH5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

158190:SPIGRAPES RS15790
gene id: 158190:SPIGRAPES_RS15790
uniprot id: G8QQJ1
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15415
gene id: 158190:SPIGRAPES_RS15415
uniprot id: G8QYY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

158190:SPIGRAPES RS08390
gene id: 158190:SPIGRAPES_RS08390
uniprot id: G8QWY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS09225
gene id: 158190:SPIGRAPES_RS09225
uniprot id: G8QY86
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

158190:SPIGRAPES RS13255
gene id: 158190:SPIGRAPES_RS13255
uniprot id: G8QVA4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

158190:SPIGRAPES RS13690
gene id: 158190:SPIGRAPES_RS13690
uniprot id: G8QVX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

158190:SPIGRAPES RS10990
gene id: 158190:SPIGRAPES_RS10990
uniprot id: G8QRY4
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS05105
gene id: 158190:SPIGRAPES_RS05105
uniprot id: G8QRS0
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS02950
gene id: 158190:SPIGRAPES_RS02950
uniprot id: G8QXE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

158190:SPIGRAPES RS06685
gene id: 158190:SPIGRAPES_RS06685
uniprot id: G8QTY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

158190:SPIGRAPES RS02945
gene id: 158190:SPIGRAPES_RS02945
uniprot id: G8QXE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Membrane

158190:SPIGRAPES RS00605
gene id: 158190:SPIGRAPES_RS00605
uniprot id: G8QTM3
names: Similarity
messages: Belongs to the RecJ family.

158190:SPIGRAPES RS07010
gene id: 158190:SPIGRAPES_RS07010
uniprot id: G8QUJ0
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS08835
gene id: 158190:SPIGRAPES_RS08835
uniprot id: G8QXL1
names: Similarity
messages: Belongs to the BMP lipoprotein family.

158190:SPIGRAPES RS08545
gene id: 158190:SPIGRAPES_RS08545
uniprot id: G8QX12
names: Similarity
messages: Belongs to the DapA family.

158190:SPIGRAPES RS03800
gene id: 158190:SPIGRAPES_RS03800
uniprot id: G8QYP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

158190:SPIGRAPES RS08765
gene id: 158190:SPIGRAPES_RS08765
uniprot id: G8QXJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS05875
gene id: 158190:SPIGRAPES_RS05875
uniprot id: G8QSP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

158190:SPIGRAPES RS03215
gene id: 158190:SPIGRAPES_RS03215
uniprot id: G8QXY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

158190:SPIGRAPES RS06750
gene id: 158190:SPIGRAPES_RS06750
uniprot id: G8QUE0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

158190:SPIGRAPES RS11435
gene id: 158190:SPIGRAPES_RS11435
uniprot id: G8QSE2
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS10740
gene id: 158190:SPIGRAPES_RS10740
uniprot id: G8QRL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

158190:SPIGRAPES RS01510
gene id: 158190:SPIGRAPES_RS01510
uniprot id: G8QUY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

158190:SPIGRAPES RS12940
gene id: 158190:SPIGRAPES_RS12940
uniprot id: G8QUP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

158190:SPIGRAPES RS02120
gene id: 158190:SPIGRAPES_RS02120
uniprot id: G8QW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

158190:SPIGRAPES RS02970
gene id: 158190:SPIGRAPES_RS02970
uniprot id: G8QXE7
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

158190:SPIGRAPES RS01895
gene id: 158190:SPIGRAPES_RS01895
uniprot id: G8QVK8
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS04680
gene id: 158190:SPIGRAPES_RS04680
uniprot id: G8QRB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS01960
gene id: 158190:SPIGRAPES_RS01960
uniprot id: G8QW10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

158190:SPIGRAPES RS03055
gene id: 158190:SPIGRAPES_RS03055
uniprot id: G8QXF8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

158190:SPIGRAPES RS04490
gene id: 158190:SPIGRAPES_RS04490
uniprot id: G8QQV3
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS00015
gene id: 158190:SPIGRAPES_RS00015
uniprot id: G8QSH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS15595
gene id: 158190:SPIGRAPES_RS15595
uniprot id: G8QZ23
names: Similarity
messages: Belongs to the TPP enzyme family.

158190:SPIGRAPES RS12295
gene id: 158190:SPIGRAPES_RS12295
uniprot id: G8QTI7
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

158190:SPIGRAPES RS05835
gene id: 158190:SPIGRAPES_RS05835
uniprot id: G8QSN3
names: Similarity
messages: Belongs to the DEAD box helicase family.

158190:SPIGRAPES RS07160
gene id: 158190:SPIGRAPES_RS07160
uniprot id: G8QV17
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

158190:SPIGRAPES RS11625
gene id: 158190:SPIGRAPES_RS11625
uniprot id: G8QSS4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

158190:SPIGRAPES RS12990
gene id: 158190:SPIGRAPES_RS12990
uniprot id: G8QUQ9
names: Similarity
messages: Belongs to the threonine aldolase family.

158190:SPIGRAPES RS00055
gene id: 158190:SPIGRAPES_RS00055
uniprot id: G8QSI0
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS16165
gene id: 158190:SPIGRAPES_RS16165
uniprot id: G8QR60
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

158190:SPIGRAPES RS10910
gene id: 158190:SPIGRAPES_RS10910
uniprot id: G8QRW8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS05325
gene id: 158190:SPIGRAPES_RS05325
uniprot id: G8QS36
names: Similarity
messages: Belongs to the DEAD box helicase family.

158190:SPIGRAPES RS14940
gene id: 158190:SPIGRAPES_RS14940
uniprot id: G8QYA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

158190:SPIGRAPES RS00535
gene id: 158190:SPIGRAPES_RS00535
uniprot id: G8QTK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

158190:SPIGRAPES RS15890
gene id: 158190:SPIGRAPES_RS15890
uniprot id: G8QQL1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

158190:SPIGRAPES RS06315
gene id: 158190:SPIGRAPES_RS06315
uniprot id: G8QTB7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

158190:SPIGRAPES RS10785
gene id: 158190:SPIGRAPES_RS10785
uniprot id: G8QRL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

158190:SPIGRAPES RS10140
gene id: 158190:SPIGRAPES_RS10140
uniprot id: G8QQX7
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS02060
gene id: 158190:SPIGRAPES_RS02060
uniprot id: G8QW30
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

158190:SPIGRAPES RS15990
gene id: 158190:SPIGRAPES_RS15990
uniprot id: G8QQN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Cytoplasm

158190:SPIGRAPES RS10685
gene id: 158190:SPIGRAPES_RS10685
uniprot id: G8QRJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

158190:SPIGRAPES RS02925
gene id: 158190:SPIGRAPES_RS02925
uniprot id: G8QXD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

158190:SPIGRAPES RS16305
gene id: 158190:SPIGRAPES_RS16305
uniprot id: G8QR88
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

158190:SPIGRAPES RS15005
gene id: 158190:SPIGRAPES_RS15005
uniprot id: G8QYC0
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

158190:SPIGRAPES RS04800
gene id: 158190:SPIGRAPES_RS04800
uniprot id: G8QRE3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

158190:SPIGRAPES RS02835
gene id: 158190:SPIGRAPES_RS02835
uniprot id: G8QXC2
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

158190:SPIGRAPES RS10145
gene id: 158190:SPIGRAPES_RS10145
uniprot id: G8QQX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS00450
gene id: 158190:SPIGRAPES_RS00450
uniprot id: G8QT50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS06915
gene id: 158190:SPIGRAPES_RS06915
uniprot id: G8QUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

158190:SPIGRAPES RS13120
gene id: 158190:SPIGRAPES_RS13120
uniprot id: G8QV77
names: Similarity
messages: Belongs to the peptidase S33 family.

158190:SPIGRAPES RS07615
gene id: 158190:SPIGRAPES_RS07615
uniprot id: G8QVQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS11840
gene id: 158190:SPIGRAPES_RS11840
uniprot id: G8QSW4
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

158190:SPIGRAPES RS11570
gene id: 158190:SPIGRAPES_RS11570
uniprot id: G8QSG5
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS09450
gene id: 158190:SPIGRAPES_RS09450
uniprot id: G8QYR9
names: Similarity
messages: Belongs to the peptidase M24B family.

158190:SPIGRAPES RS05965
gene id: 158190:SPIGRAPES_RS05965
uniprot id: G8QSQ9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS06495
gene id: 158190:SPIGRAPES_RS06495
uniprot id: G8QTU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS10555
gene id: 158190:SPIGRAPES_RS10555
uniprot id: G8QRH4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

158190:SPIGRAPES RS01920
gene id: 158190:SPIGRAPES_RS01920
uniprot id: G8QVL3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

158190:SPIGRAPES RS06710
gene id: 158190:SPIGRAPES_RS06710
uniprot id: G8QTY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS10620
gene id: 158190:SPIGRAPES_RS10620
uniprot id: G8QRI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

158190:SPIGRAPES RS08990
gene id: 158190:SPIGRAPES_RS08990
uniprot id: G8QY40
names: Similarity
messages: Belongs to the glutamate synthase family.

158190:SPIGRAPES RS02010
gene id: 158190:SPIGRAPES_RS02010
uniprot id: G8QW20
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA.

158190:SPIGRAPES RS07410
gene id: 158190:SPIGRAPES_RS07410
uniprot id: G8QV68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Monomer.

158190:SPIGRAPES RS12475
gene id: 158190:SPIGRAPES_RS12475
uniprot id: G8QU17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

158190:SPIGRAPES RS10510
gene id: 158190:SPIGRAPES_RS10510
uniprot id: G8QRG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

158190:SPIGRAPES RS11125
gene id: 158190:SPIGRAPES_RS11125
uniprot id: G8QS11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS01345
gene id: 158190:SPIGRAPES_RS01345
uniprot id: G8QUV7
names: Similarity
messages: Belongs to the DEAD box helicase family.

158190:SPIGRAPES RS10050
gene id: 158190:SPIGRAPES_RS10050
uniprot id: G8QQG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS03320
gene id: 158190:SPIGRAPES_RS03320
uniprot id: G8QY08
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

158190:SPIGRAPES RS12350
gene id: 158190:SPIGRAPES_RS12350
uniprot id: G8QTJ8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

158190:SPIGRAPES RS11700
gene id: 158190:SPIGRAPES_RS11700
uniprot id: G8QST9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS03430
gene id: 158190:SPIGRAPES_RS03430
uniprot id: G8QY29
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

158190:SPIGRAPES RS10890
gene id: 158190:SPIGRAPES_RS10890
uniprot id: G8QRW4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

158190:SPIGRAPES RS06065
gene id: 158190:SPIGRAPES_RS06065
uniprot id: G8QT72
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

158190:SPIGRAPES RS16270
gene id: 158190:SPIGRAPES_RS16270
uniprot id: G8QR81
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

158190:SPIGRAPES RS12465
gene id: 158190:SPIGRAPES_RS12465
uniprot id: G8QU15
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

158190:SPIGRAPES RS15235
gene id: 158190:SPIGRAPES_RS15235
uniprot id: G8QYG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

158190:SPIGRAPES RS01860
gene id: 158190:SPIGRAPES_RS01860
uniprot id: G8QVK1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS10905
gene id: 158190:SPIGRAPES_RS10905
uniprot id: G8QRW7
names: Similarity
messages: Belongs to the CinA family.

158190:SPIGRAPES RS13700
gene id: 158190:SPIGRAPES_RS13700
uniprot id: G8QVY1
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

158190:SPIGRAPES RS08770
gene id: 158190:SPIGRAPES_RS08770
uniprot id: G8QXJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS00385
gene id: 158190:SPIGRAPES_RS00385
uniprot id: G8QT37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

158190:SPIGRAPES RS13755
gene id: 158190:SPIGRAPES_RS13755
uniprot id: G8QVZ2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

158190:SPIGRAPES RS03190
gene id: 158190:SPIGRAPES_RS03190
uniprot id: G8QXY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

158190:SPIGRAPES RS09960
gene id: 158190:SPIGRAPES_RS09960
uniprot id: G8QQE4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

158190:SPIGRAPES RS03790
gene id: 158190:SPIGRAPES_RS03790
uniprot id: G8QYN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

158190:SPIGRAPES RS07050
gene id: 158190:SPIGRAPES_RS07050
uniprot id: G8QUJ8
names: Similarity
messages: Belongs to the BtpA family.

158190:SPIGRAPES RS10735
gene id: 158190:SPIGRAPES_RS10735
uniprot id: G8QRK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

158190:SPIGRAPES RS07805
gene id: 158190:SPIGRAPES_RS07805
uniprot id: G8QVT7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

158190:SPIGRAPES RS02055
gene id: 158190:SPIGRAPES_RS02055
uniprot id: G8QW29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

158190:SPIGRAPES RS10835
gene id: 158190:SPIGRAPES_RS10835
uniprot id: G8QRM9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS13970
gene id: 158190:SPIGRAPES_RS13970
uniprot id: G8QWI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

158190:SPIGRAPES RS11105
gene id: 158190:SPIGRAPES_RS11105
uniprot id: G8QS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS01070
gene id: 158190:SPIGRAPES_RS01070
uniprot id: G8QUB1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

158190:SPIGRAPES RS03835
gene id: 158190:SPIGRAPES_RS03835
uniprot id: G8QQ34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

158190:SPIGRAPES RS07670
gene id: 158190:SPIGRAPES_RS07670
uniprot id: G8QVR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS00525
gene id: 158190:SPIGRAPES_RS00525
uniprot id: G8QTK6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

158190:SPIGRAPES RS07185
gene id: 158190:SPIGRAPES_RS07185
uniprot id: G8QV22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS01835
gene id: 158190:SPIGRAPES_RS01835
uniprot id: G8QVJ6
names: Function
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.

158190:SPIGRAPES RS15390
gene id: 158190:SPIGRAPES_RS15390
uniprot id: G8QYY3
names: Similarity
messages: Belongs to the RutC family.

158190:SPIGRAPES RS10805
gene id: 158190:SPIGRAPES_RS10805
uniprot id: G8QRM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

158190:SPIGRAPES RS11050
gene id: 158190:SPIGRAPES_RS11050
uniprot id: G8QRZ6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

158190:SPIGRAPES RS03220
gene id: 158190:SPIGRAPES_RS03220
uniprot id: G8QXY7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

158190:SPIGRAPES RS05270
gene id: 158190:SPIGRAPES_RS05270
uniprot id: G8QRV4
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

158190:SPIGRAPES RS02385
gene id: 158190:SPIGRAPES_RS02385
uniprot id: G8QWP2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

158190:SPIGRAPES RS07135
gene id: 158190:SPIGRAPES_RS07135
uniprot id: G8QV12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS15720
gene id: 158190:SPIGRAPES_RS15720
uniprot id: G8QQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

158190:SPIGRAPES RS12575
gene id: 158190:SPIGRAPES_RS12575
uniprot id: G8QU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

158190:SPIGRAPES RS02830
gene id: 158190:SPIGRAPES_RS02830
uniprot id: G8QXC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS04275
gene id: 158190:SPIGRAPES_RS04275
uniprot id: G8QQR1
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS00835
gene id: 158190:SPIGRAPES_RS00835
uniprot id: G8QTR9
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS12585
gene id: 158190:SPIGRAPES_RS12585
uniprot id: G8QU39
names: Similarity
messages: Belongs to the LacAB/RpiB family.

158190:SPIGRAPES RS15120
gene id: 158190:SPIGRAPES_RS15120
uniprot id: G8QYE1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

158190:SPIGRAPES RS03645
gene id: 158190:SPIGRAPES_RS03645
uniprot id: G8QYL1
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

158190:SPIGRAPES RS08055
gene id: 158190:SPIGRAPES_RS08055
uniprot id: G8QWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS04440
gene id: 158190:SPIGRAPES_RS04440
uniprot id: G8QQU3
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

158190:SPIGRAPES RS06865
gene id: 158190:SPIGRAPES_RS06865
uniprot id: G8QUG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

158190:SPIGRAPES RS03630
gene id: 158190:SPIGRAPES_RS03630
uniprot id: G8QYK8
names: Similarity
messages: Belongs to the universal stress protein A family.

158190:SPIGRAPES RS05290
gene id: 158190:SPIGRAPES_RS05290
uniprot id: G8QS30
names: Similarity
messages: Belongs to the BMP lipoprotein family.

158190:SPIGRAPES RS06475
gene id: 158190:SPIGRAPES_RS06475
uniprot id: G8QTU1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

158190:SPIGRAPES RS13555
gene id: 158190:SPIGRAPES_RS13555
uniprot id: G8QVV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

158190:SPIGRAPES RS09575
gene id: 158190:SPIGRAPES_RS09575
uniprot id: G8QYU4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

158190:SPIGRAPES RS02870
gene id: 158190:SPIGRAPES_RS02870
uniprot id: G8QXC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

158190:SPIGRAPES RS03895
gene id: 158190:SPIGRAPES_RS03895
uniprot id: G8QQ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

158190:SPIGRAPES RS03865
gene id: 158190:SPIGRAPES_RS03865
uniprot id: G8QQ38
names: Similarity
messages: Belongs to the peptidase M29 family.

158190:SPIGRAPES RS15310
gene id: 158190:SPIGRAPES_RS15310
uniprot id: G8QYW6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

158190:SPIGRAPES RS04635
gene id: 158190:SPIGRAPES_RS04635
uniprot id: G8QRB0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

158190:SPIGRAPES RS06960
gene id: 158190:SPIGRAPES_RS06960
uniprot id: G8QUI0
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS02485
gene id: 158190:SPIGRAPES_RS02485
uniprot id: G8QWR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

158190:SPIGRAPES RS14840
gene id: 158190:SPIGRAPES_RS14840
uniprot id: G8QXU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

158190:SPIGRAPES RS02465
gene id: 158190:SPIGRAPES_RS02465
uniprot id: G8QWQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

158190:SPIGRAPES RS09860
gene id: 158190:SPIGRAPES_RS09860
uniprot id: G8QQC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS04375
gene id: 158190:SPIGRAPES_RS04375
uniprot id: G8QQT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

158190:SPIGRAPES RS08550
gene id: 158190:SPIGRAPES_RS08550
uniprot id: G8QX13
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

158190:SPIGRAPES RS13990
gene id: 158190:SPIGRAPES_RS13990
uniprot id: G8QWI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

158190:SPIGRAPES RS08440
gene id: 158190:SPIGRAPES_RS08440
uniprot id: G8QWZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

158190:SPIGRAPES RS12300
gene id: 158190:SPIGRAPES_RS12300
uniprot id: G8QTI8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS09670
gene id: 158190:SPIGRAPES_RS09670
uniprot id: G8QYV9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

158190:SPIGRAPES RS06460
gene id: 158190:SPIGRAPES_RS06460
uniprot id: G8QTT8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

158190:SPIGRAPES RS09465
gene id: 158190:SPIGRAPES_RS09465
uniprot id: G8QYS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

158190:SPIGRAPES RS06545
gene id: 158190:SPIGRAPES_RS06545
uniprot id: G8QTV5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

158190:SPIGRAPES RS10225
gene id: 158190:SPIGRAPES_RS10225
uniprot id: G8QQZ1
names: Subcellular Location Annotation
messages: Membrane

158190:SPIGRAPES RS15570
gene id: 158190:SPIGRAPES_RS15570
uniprot id: G8QZ18
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

158190:SPIGRAPES RS13410
gene id: 158190:SPIGRAPES_RS13410
uniprot id: G8QVD4
names: Similarity
messages: Belongs to the DprA/Smf family.

158190:SPIGRAPES RS11930
gene id: 158190:SPIGRAPES_RS11930
uniprot id: G8QSY0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

158190:SPIGRAPES RS14075
gene id: 158190:SPIGRAPES_RS14075
uniprot id: G8QWK3
names: Subcellular Location Annotation
messages: Virion