1580092:NADRNF5 RS04560
gene id: 1580092:NADRNF5_RS04560
uniprot id: A0A0D5C2K4
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1580092:NADRNF5 RS02190
gene id: 1580092:NADRNF5_RS02190
uniprot id: A0A0D5C154
names: Cofactor
messages: Binds 1 copper ion per subunit.

1580092:NADRNF5 RS10295
gene id: 1580092:NADRNF5_RS10295
uniprot id: A0A0D5C645
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS05640
gene id: 1580092:NADRNF5_RS05640
uniprot id: A0A0D5C2W0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1580092:NADRNF5 RS01925
gene id: 1580092:NADRNF5_RS01925
uniprot id: A0A0D5C047
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1580092:NADRNF5 RS00025
gene id: 1580092:NADRNF5_RS00025
uniprot id: A0A0D5BYT1
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS04225
gene id: 1580092:NADRNF5_RS04225
uniprot id: A0A0D5C2D6
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1580092:NADRNF5 RS03725
gene id: 1580092:NADRNF5_RS03725
uniprot id: A0A0D5C2A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1580092:NADRNF5 RS04740
gene id: 1580092:NADRNF5_RS04740
uniprot id: A0A0D5C272
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

1580092:NADRNF5 RS03940
gene id: 1580092:NADRNF5_RS03940
uniprot id: A0A0D5C1S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1580092:NADRNF5 RS05885
gene id: 1580092:NADRNF5_RS05885
uniprot id: A0A0D5C3E9
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS08450
gene id: 1580092:NADRNF5_RS08450
uniprot id: A0A0D5C525
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1580092:NADRNF5 RS00380
gene id: 1580092:NADRNF5_RS00380
uniprot id: A0A0D5BYZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS02430
gene id: 1580092:NADRNF5_RS02430
uniprot id: A0A0D5C1A1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA.

1580092:NADRNF5 RS08780
gene id: 1580092:NADRNF5_RS08780
uniprot id: A0A0D5C4P1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1580092:NADRNF5 RS10065
gene id: 1580092:NADRNF5_RS10065
uniprot id: A0A0D5C4W9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1580092:NADRNF5 RS08275
gene id: 1580092:NADRNF5_RS08275
uniprot id: A0A0D5C4Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

1580092:NADRNF5 RS00310
gene id: 1580092:NADRNF5_RS00310
uniprot id: A0A0D5C0A4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1580092:NADRNF5 RS08860
gene id: 1580092:NADRNF5_RS08860
uniprot id: A0A0D5C569
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS03195
gene id: 1580092:NADRNF5_RS03195
uniprot id: A0A0D5C1V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).

1580092:NADRNF5 RS00485
gene id: 1580092:NADRNF5_RS00485
uniprot id: A0A0D5BZ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1580092:NADRNF5 RS09715
gene id: 1580092:NADRNF5_RS09715
uniprot id: A0A0D5C5R7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1580092:NADRNF5 RS04910
gene id: 1580092:NADRNF5_RS04910
uniprot id: A0A0D5C302
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1580092:NADRNF5 RS06205
gene id: 1580092:NADRNF5_RS06205
uniprot id: A0A0D5C2G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1580092:NADRNF5 RS08020
gene id: 1580092:NADRNF5_RS08020
uniprot id: A0A0D5C4R1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1580092:NADRNF5 RS02440
gene id: 1580092:NADRNF5_RS02440
uniprot id: A0A0D5C061
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

1580092:NADRNF5 RS06080
gene id: 1580092:NADRNF5_RS06080
uniprot id: A0A0D5C3I5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

1580092:NADRNF5 RS00415
gene id: 1580092:NADRNF5_RS00415
uniprot id: A0A0D5BZ85
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1580092:NADRNF5 RS07720
gene id: 1580092:NADRNF5_RS07720
uniprot id: A0A0D5C450
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS01360
gene id: 1580092:NADRNF5_RS01360
uniprot id: A0A0D5C090
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1580092:NADRNF5 RS08620
gene id: 1580092:NADRNF5_RS08620
uniprot id: A0A0D5C557
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1580092:NADRNF5 RS00955
gene id: 1580092:NADRNF5_RS00955
uniprot id: A0A0D5BZC7
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

1580092:NADRNF5 RS01980
gene id: 1580092:NADRNF5_RS01980
uniprot id: A0A0D5C0J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1580092:NADRNF5 RS03905
gene id: 1580092:NADRNF5_RS03905
uniprot id: A0A0D5C1A4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1580092:NADRNF5 RS02040
gene id: 1580092:NADRNF5_RS02040
uniprot id: A0A0D5C064
names: Subcellular Location Annotation
messages: Mitochondrion

1580092:NADRNF5 RS05795
gene id: 1580092:NADRNF5_RS05795
uniprot id: A0A0D5C2G9
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1580092:NADRNF5 RS00700
gene id: 1580092:NADRNF5_RS00700
uniprot id: A0A0D5BZW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

1580092:NADRNF5 RS01630
gene id: 1580092:NADRNF5_RS01630
uniprot id: A0A0D5BZY6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1580092:NADRNF5 RS00710
gene id: 1580092:NADRNF5_RS00710
uniprot id: A0A0D5C0J9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1580092:NADRNF5 RS01500
gene id: 1580092:NADRNF5_RS01500
uniprot id: A0A0D5C0B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1580092:NADRNF5 RS06070
gene id: 1580092:NADRNF5_RS06070
uniprot id: A0A0D5C3P1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1580092:NADRNF5 RS08535
gene id: 1580092:NADRNF5_RS08535
uniprot id: A0A0D5C501
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1580092:NADRNF5 RS00505
gene id: 1580092:NADRNF5_RS00505
uniprot id: A0A0D5BZS6
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS01375
gene id: 1580092:NADRNF5_RS01375
uniprot id: A0A0D5BZU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

1580092:NADRNF5 RS07475
gene id: 1580092:NADRNF5_RS07475
uniprot id: A0A0D5C363
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1580092:NADRNF5 RS01065
gene id: 1580092:NADRNF5_RS01065
uniprot id: A0A0D5C0I7
names: Similarity
messages: Belongs to the glutaredoxin family.

1580092:NADRNF5 RS07740
gene id: 1580092:NADRNF5_RS07740
uniprot id: A0A0D5C456
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1580092:NADRNF5 RS06260
gene id: 1580092:NADRNF5_RS06260
uniprot id: A0A0D5C3M0
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS02390
gene id: 1580092:NADRNF5_RS02390
uniprot id: A0A0D5C0S7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1580092:NADRNF5 RS06825
gene id: 1580092:NADRNF5_RS06825
uniprot id: A0A0D5C320
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

1580092:NADRNF5 RS03475
gene id: 1580092:NADRNF5_RS03475
uniprot id: A0A0D5C128
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

1580092:NADRNF5 RS02060
gene id: 1580092:NADRNF5_RS02060
uniprot id: A0A0D5BZY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1580092:NADRNF5 RS08115
gene id: 1580092:NADRNF5_RS08115
uniprot id: A0A0D5C4S7
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS05805
gene id: 1580092:NADRNF5_RS05805
uniprot id: A0A0D5C2Y9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS01470
gene id: 1580092:NADRNF5_RS01470
uniprot id: A0A0D5BZW0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Membrane

1580092:NADRNF5 RS00300
gene id: 1580092:NADRNF5_RS00300
uniprot id: A0A0D5BZL4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1580092:NADRNF5 RS03390
gene id: 1580092:NADRNF5_RS03390
uniprot id: A0A0D5C0T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1580092:NADRNF5 RS04305
gene id: 1580092:NADRNF5_RS04305
uniprot id: A0A0D5C2M1
names: Similarity
messages: Belongs to the UPF0111 family.

1580092:NADRNF5 RS08560
gene id: 1580092:NADRNF5_RS08560
uniprot id: A0A0D5C506
names: Similarity
messages: Belongs to the TPP enzyme family.

1580092:NADRNF5 RS10375
gene id: 1580092:NADRNF5_RS10375
uniprot id: A0A0D5C629
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

1580092:NADRNF5 RS06895
gene id: 1580092:NADRNF5_RS06895
uniprot id: A0A0D5C333
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS01265
gene id: 1580092:NADRNF5_RS01265
uniprot id: A0A0D5BZI3
names: Similarity
messages: Belongs to the PDCD5 family.

1580092:NADRNF5 RS04645
gene id: 1580092:NADRNF5_RS04645
uniprot id: A0A0D5C1I6
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1580092:NADRNF5 RS08035
gene id: 1580092:NADRNF5_RS08035
uniprot id: A0A0D5C4V1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1580092:NADRNF5 RS00690
gene id: 1580092:NADRNF5_RS00690
uniprot id: A0A0D5BZH1
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS05120
gene id: 1580092:NADRNF5_RS05120
uniprot id: A0A0D5C2W7
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1580092:NADRNF5 RS01525
gene id: 1580092:NADRNF5_RS01525
uniprot id: A0A0D5C0S4
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1580092:NADRNF5 RS10540
gene id: 1580092:NADRNF5_RS10540
uniprot id: A0A0D5C5R8
names: Similarity
messages: Belongs to the eIF-2-alpha family.

1580092:NADRNF5 RS01595
gene id: 1580092:NADRNF5_RS01595
uniprot id: A0A0D5C119
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

1580092:NADRNF5 RS03715
gene id: 1580092:NADRNF5_RS03715
uniprot id: A0A0D5C1N2
names: Similarity
messages: Belongs to the GARS family.

1580092:NADRNF5 RS01735
gene id: 1580092:NADRNF5_RS01735
uniprot id: A0A0D5C010
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS03190
gene id: 1580092:NADRNF5_RS03190
uniprot id: A0A0D5C0X4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS00385
gene id: 1580092:NADRNF5_RS00385
uniprot id: A0A0D5C0C0
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1580092:NADRNF5 RS10330
gene id: 1580092:NADRNF5_RS10330
uniprot id: A0A0D5C5N2
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS03415
gene id: 1580092:NADRNF5_RS03415
uniprot id: A0A0D5C0U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1580092:NADRNF5 RS04220
gene id: 1580092:NADRNF5_RS04220
uniprot id: A0A0D5C1G7
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1580092:NADRNF5 RS03205
gene id: 1580092:NADRNF5_RS03205
uniprot id: A0A0D5C0Q5
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

1580092:NADRNF5 RS03950
gene id: 1580092:NADRNF5_RS03950
uniprot id: A0A0D5C2F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1580092:NADRNF5 RS06750
gene id: 1580092:NADRNF5_RS06750
uniprot id: A0A0D5C2S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1580092:NADRNF5 RS00580
gene id: 1580092:NADRNF5_RS00580
uniprot id: A0A0D5BZ59
names: Similarity
messages: Belongs to the aspartokinase family.

1580092:NADRNF5 RS00825
gene id: 1580092:NADRNF5_RS00825
uniprot id: A0A0D5BZA3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1580092:NADRNF5 RS09145
gene id: 1580092:NADRNF5_RS09145
uniprot id: A0A0D5C5G9
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

1580092:NADRNF5 RS09015
gene id: 1580092:NADRNF5_RS09015
uniprot id: A0A0D5C5E3
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

1580092:NADRNF5 RS09260
gene id: 1580092:NADRNF5_RS09260
uniprot id: A0A0D5C4I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1580092:NADRNF5 RS02290
gene id: 1580092:NADRNF5_RS02290
uniprot id: A0A0D5C033
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

1580092:NADRNF5 RS07005
gene id: 1580092:NADRNF5_RS07005
uniprot id: A0A0D5C425
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS00225
gene id: 1580092:NADRNF5_RS00225
uniprot id: A0A0D5BYW7
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1580092:NADRNF5 RS03270
gene id: 1580092:NADRNF5_RS03270
uniprot id: A0A0D5C226
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

1580092:NADRNF5 RS00050
gene id: 1580092:NADRNF5_RS00050
uniprot id: A0A0D5BYT6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1580092:NADRNF5 RS07500
gene id: 1580092:NADRNF5_RS07500
uniprot id: A0A0D5C3F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1580092:NADRNF5 RS01760
gene id: 1580092:NADRNF5_RS01760
uniprot id: A0A0D5C015
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

1580092:NADRNF5 RS00925
gene id: 1580092:NADRNF5_RS00925
uniprot id: A0A0D5C0G2
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1580092:NADRNF5 RS07960
gene id: 1580092:NADRNF5_RS07960
uniprot id: A0A0D5C3T3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1580092:NADRNF5 RS03710
gene id: 1580092:NADRNF5_RS03710
uniprot id: A0A0D5C235
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1580092:NADRNF5 RS04310
gene id: 1580092:NADRNF5_RS04310
uniprot id: A0A0D5C1I5
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

1580092:NADRNF5 RS05710
gene id: 1580092:NADRNF5_RS05710
uniprot id: A0A0D5C2F5
names: Subunit
messages: Homodimer.

1580092:NADRNF5 RS05940
gene id: 1580092:NADRNF5_RS05940
uniprot id: A0A0D5C2B3
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS09195
gene id: 1580092:NADRNF5_RS09195
uniprot id: A0A0D5C472
names: Similarity
messages: Belongs to the isopentenyl phosphate kinase family.

1580092:NADRNF5 RS10545
gene id: 1580092:NADRNF5_RS10545
uniprot id: A0A0D5C4Z8
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

1580092:NADRNF5 RS01115
gene id: 1580092:NADRNF5_RS01115
uniprot id: A0A0D5BZF5
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

1580092:NADRNF5 RS02655
gene id: 1580092:NADRNF5_RS02655
uniprot id: A0A0D5C0I0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1580092:NADRNF5 RS03645
gene id: 1580092:NADRNF5_RS03645
uniprot id: A0A0D5C0Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1580092:NADRNF5 RS08265
gene id: 1580092:NADRNF5_RS08265
uniprot id: A0A0D5C4F7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1580092:NADRNF5 RS08510
gene id: 1580092:NADRNF5_RS08510
uniprot id: A0A0D5C4Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1580092:NADRNF5 RS01685
gene id: 1580092:NADRNF5_RS01685
uniprot id: A0A0D5C0V6
names: Similarity
messages: Belongs to the peptidase S8 family.

1580092:NADRNF5 RS04140
gene id: 1580092:NADRNF5_RS04140
uniprot id: A0A0D5C2J3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1580092:NADRNF5 RS00395
gene id: 1580092:NADRNF5_RS00395
uniprot id: A0A0D5C034
names: Similarity
messages: Belongs to the glutamine synthetase family.

1580092:NADRNF5 RS01490
gene id: 1580092:NADRNF5_RS01490
uniprot id: A0A0D5BZW5
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS07810
gene id: 1580092:NADRNF5_RS07810
uniprot id: A0A0D5C3Q3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

1580092:NADRNF5 RS03530
gene id: 1580092:NADRNF5_RS03530
uniprot id: A0A0D5C210
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1580092:NADRNF5 RS05895
gene id: 1580092:NADRNF5_RS05895
uniprot id: A0A0D5C2A4
names: Similarity
messages: Belongs to the ATPase gamma chain family.

1580092:NADRNF5 RS08455
gene id: 1580092:NADRNF5_RS08455
uniprot id: A0A0D5C427
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1580092:NADRNF5 RS09070
gene id: 1580092:NADRNF5_RS09070
uniprot id: A0A0D5C4F6
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

1580092:NADRNF5 RS03795
gene id: 1580092:NADRNF5_RS03795
uniprot id: A0A0D5C117
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1580092:NADRNF5 RS08280
gene id: 1580092:NADRNF5_RS08280
uniprot id: A0A0D5C3Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

1580092:NADRNF5 RS07175
gene id: 1580092:NADRNF5_RS07175
uniprot id: A0A0D5C4B1
names: Similarity
messages: Belongs to the glutaredoxin family.

1580092:NADRNF5 RS00045
gene id: 1580092:NADRNF5_RS00045
uniprot id: A0A0D5BZF4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1580092:NADRNF5 RS06005
gene id: 1580092:NADRNF5_RS06005
uniprot id: A0A0D5C2K9
names: Similarity
messages: Belongs to the peptidase T1A family.

1580092:NADRNF5 RS04170
gene id: 1580092:NADRNF5_RS04170
uniprot id: A0A0D5C1F7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1580092:NADRNF5 RS02055
gene id: 1580092:NADRNF5_RS02055
uniprot id: A0A0D5C0L0
names: Similarity
messages: Belongs to the PdxS/SNZ family.

1580092:NADRNF5 RS08260
gene id: 1580092:NADRNF5_RS08260
uniprot id: A0A0D5C4V4
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

1580092:NADRNF5 RS09025
gene id: 1580092:NADRNF5_RS09025
uniprot id: A0A0D5C5A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

1580092:NADRNF5 RS08985
gene id: 1580092:NADRNF5_RS08985
uniprot id: A0A0D5C5D7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: Part of the 30S ribosomal subunit.

1580092:NADRNF5 RS07665
gene id: 1580092:NADRNF5_RS07665
uniprot id: A0A0D5C4P0
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS10115
gene id: 1580092:NADRNF5_RS10115
uniprot id: A0A0D5C607
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1580092:NADRNF5 RS06175
gene id: 1580092:NADRNF5_RS06175
uniprot id: A0A0D5C3K2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1580092:NADRNF5 RS09345
gene id: 1580092:NADRNF5_RS09345
uniprot id: A0A0D5C5J7
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS07715
gene id: 1580092:NADRNF5_RS07715
uniprot id: A0A0D5C4L0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS08320
gene id: 1580092:NADRNF5_RS08320
uniprot id: A0A0D5C3Q4
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

1580092:NADRNF5 RS02425
gene id: 1580092:NADRNF5_RS02425
uniprot id: A0A0D5C0E1
names: Caution
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS06060
gene id: 1580092:NADRNF5_RS06060
uniprot id: A0A0D5C334
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

1580092:NADRNF5 RS06575
gene id: 1580092:NADRNF5_RS06575
uniprot id: A0A0D5C3T7
names: Function
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

1580092:NADRNF5 RS01110
gene id: 1580092:NADRNF5_RS01110
uniprot id: A0A0D5C049
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS08080
gene id: 1580092:NADRNF5_RS08080
uniprot id: A0A0D5C4W2
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS00240
gene id: 1580092:NADRNF5_RS00240
uniprot id: A0A0D5BZZ2
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1580092:NADRNF5 RS03460
gene id: 1580092:NADRNF5_RS03460
uniprot id: A0A0D5C1J2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Membrane

1580092:NADRNF5 RS00055
gene id: 1580092:NADRNF5_RS00055
uniprot id: A0A0D5C058
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.
messages: Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.

1580092:NADRNF5 RS10410
gene id: 1580092:NADRNF5_RS10410
uniprot id: A0A0D5C4Y0
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1580092:NADRNF5 RS04770
gene id: 1580092:NADRNF5_RS04770
uniprot id: A0A0D5C1K9
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS05800
gene id: 1580092:NADRNF5_RS05800
uniprot id: A0A0D5C3D0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1580092:NADRNF5 RS02150
gene id: 1580092:NADRNF5_RS02150
uniprot id: A0A0D5C0M8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1580092:NADRNF5 RS10440
gene id: 1580092:NADRNF5_RS10440
uniprot id: A0A0D5C4Y3
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

1580092:NADRNF5 RS03400
gene id: 1580092:NADRNF5_RS03400
uniprot id: A0A0D5C113
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

1580092:NADRNF5 RS07870
gene id: 1580092:NADRNF5_RS07870
uniprot id: A0A0D5C481
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1580092:NADRNF5 RS08725
gene id: 1580092:NADRNF5_RS08725
uniprot id: A0A0D5C478
names: Similarity
messages: Belongs to the PstS family.

1580092:NADRNF5 RS02740
gene id: 1580092:NADRNF5_RS02740
uniprot id: A0A0D5C0J8
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS06085
gene id: 1580092:NADRNF5_RS06085
uniprot id: A0A0D5C338
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

1580092:NADRNF5 RS01655
gene id: 1580092:NADRNF5_RS01655
uniprot id: A0A0D5BZZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1580092:NADRNF5 RS01865
gene id: 1580092:NADRNF5_RS01865
uniprot id: A0A0D5C0H5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1580092:NADRNF5 RS01695
gene id: 1580092:NADRNF5_RS01695
uniprot id: A0A0D5BZR1
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS00565
gene id: 1580092:NADRNF5_RS00565
uniprot id: A0A0D5BZE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1580092:NADRNF5 RS00570
gene id: 1580092:NADRNF5_RS00570
uniprot id: A0A0D5C097
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

1580092:NADRNF5 RS00090
gene id: 1580092:NADRNF5_RS00090
uniprot id: A0A0D5BZW1
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1580092:NADRNF5 RS07695
gene id: 1580092:NADRNF5_RS07695
uniprot id: A0A0D5C444
names: Similarity
messages: Belongs to the UbiD family.

1580092:NADRNF5 RS04760
gene id: 1580092:NADRNF5_RS04760
uniprot id: A0A0D5C2P1
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

1580092:NADRNF5 RS05425
gene id: 1580092:NADRNF5_RS05425
uniprot id: A0A0D5C3C1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1580092:NADRNF5 RS08305
gene id: 1580092:NADRNF5_RS08305
uniprot id: A0A0D5C403
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1580092:NADRNF5 RS01645
gene id: 1580092:NADRNF5_RS01645
uniprot id: A0A0D5BZQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1580092:NADRNF5 RS05290
gene id: 1580092:NADRNF5_RS05290
uniprot id: A0A0D5C269
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates influx of magnesium ions.
messages: Membrane

1580092:NADRNF5 RS09030
gene id: 1580092:NADRNF5_RS09030
uniprot id: A0A0D5C4U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1580092:NADRNF5 RS01225
gene id: 1580092:NADRNF5_RS01225
uniprot id: A0A0D5C0M2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1580092:NADRNF5 RS07420
gene id: 1580092:NADRNF5_RS07420
uniprot id: A0A0D5C4B8
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

1580092:NADRNF5 RS00340
gene id: 1580092:NADRNF5_RS00340
uniprot id: A0A0D5BZ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

1580092:NADRNF5 RS09625
gene id: 1580092:NADRNF5_RS09625
uniprot id: A0A0D5C4N9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1580092:NADRNF5 RS09525
gene id: 1580092:NADRNF5_RS09525
uniprot id: A0A0D5C5K5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1580092:NADRNF5 RS01135
gene id: 1580092:NADRNF5_RS01135
uniprot id: A0A0D5C052
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS07700
gene id: 1580092:NADRNF5_RS07700
uniprot id: A0A0D5C3E0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1580092:NADRNF5 RS04160
gene id: 1580092:NADRNF5_RS04160
uniprot id: A0A0D5C183
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1580092:NADRNF5 RS03385
gene id: 1580092:NADRNF5_RS03385
uniprot id: A0A0D5C1H6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

1580092:NADRNF5 RS10600
gene id: 1580092:NADRNF5_RS10600
uniprot id: A0A0D5C507
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1580092:NADRNF5 RS01750
gene id: 1580092:NADRNF5_RS01750
uniprot id: A0A0D5BZS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.

1580092:NADRNF5 RS00140
gene id: 1580092:NADRNF5_RS00140
uniprot id: A0A0D5BZX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1580092:NADRNF5 RS09250
gene id: 1580092:NADRNF5_RS09250
uniprot id: A0A0D5C482
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1580092:NADRNF5 RS09510
gene id: 1580092:NADRNF5_RS09510
uniprot id: A0A0D5C5N1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

1580092:NADRNF5 RS06030
gene id: 1580092:NADRNF5_RS06030
uniprot id: A0A0D5C3H7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1580092:NADRNF5 RS08285
gene id: 1580092:NADRNF5_RS08285
uniprot id: A0A0D5C4V6
names: Similarity
messages: Belongs to the SDO1/SBDS family.

1580092:NADRNF5 RS04325
gene id: 1580092:NADRNF5_RS04325
uniprot id: A0A0D5C1B9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS03360
gene id: 1580092:NADRNF5_RS03360
uniprot id: A0A0D5C1H2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

1580092:NADRNF5 RS02145
gene id: 1580092:NADRNF5_RS02145
uniprot id: A0A0D5C145
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1580092:NADRNF5 RS01355
gene id: 1580092:NADRNF5_RS01355
uniprot id: A0A0D5C0P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

1580092:NADRNF5 RS06945
gene id: 1580092:NADRNF5_RS06945
uniprot id: A0A0D5C342
names: Similarity
messages: Belongs to the malic enzymes family.

1580092:NADRNF5 RS06050
gene id: 1580092:NADRNF5_RS06050
uniprot id: A0A0D5C2L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1580092:NADRNF5 RS04850
gene id: 1580092:NADRNF5_RS04850
uniprot id: A0A0D5C2Y6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

1580092:NADRNF5 RS09130
gene id: 1580092:NADRNF5_RS09130
uniprot id: A0A0D5C5D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1580092:NADRNF5 RS09560
gene id: 1580092:NADRNF5_RS09560
uniprot id: A0A0D5C4E0
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS03705
gene id: 1580092:NADRNF5_RS03705
uniprot id: A0A0D5C166
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Homododecamer. The 12 identical subunits form a hollow sphere into which the mineral iron core of up to 300 Fe(3+) can be deposited.
messages: Protects DNA from oxidative damage by sequestering intracellular Fe2+ ion and storing it in the form of Fe3+ oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe2+ ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: nucleoid

1580092:NADRNF5 RS07705
gene id: 1580092:NADRNF5_RS07705
uniprot id: A0A0D5C4P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

1580092:NADRNF5 RS00095
gene id: 1580092:NADRNF5_RS00095
uniprot id: A0A0D5BZG7
names: Function
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.

1580092:NADRNF5 RS04165
gene id: 1580092:NADRNF5_RS04165
uniprot id: A0A0D5C2J8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1580092:NADRNF5 RS06190
gene id: 1580092:NADRNF5_RS06190
uniprot id: A0A0D5C3R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1580092:NADRNF5 RS00940
gene id: 1580092:NADRNF5_RS00940
uniprot id: A0A0D5BZM1
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

1580092:NADRNF5 RS10550
gene id: 1580092:NADRNF5_RS10550
uniprot id: A0A0D5C689
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1580092:NADRNF5 RS00985
gene id: 1580092:NADRNF5_RS00985
uniprot id: A0A0D5C0Q2
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS09670
gene id: 1580092:NADRNF5_RS09670
uniprot id: A0A0D5C4P7
names: Similarity
messages: Belongs to the archease family.

1580092:NADRNF5 RS00080
gene id: 1580092:NADRNF5_RS00080
uniprot id: A0A0D5C063
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1580092:NADRNF5 RS09575
gene id: 1580092:NADRNF5_RS09575
uniprot id: A0A0D5C5L4
names: Subcellular Location Annotation
messages: Nucleus

1580092:NADRNF5 RS05955
gene id: 1580092:NADRNF5_RS05955
uniprot id: A0A0D5C3G4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS08270
gene id: 1580092:NADRNF5_RS08270
uniprot id: A0A0D5C3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

1580092:NADRNF5 RS09535
gene id: 1580092:NADRNF5_RS09535
uniprot id: A0A0D5C4D4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1580092:NADRNF5 RS05625
gene id: 1580092:NADRNF5_RS05625
uniprot id: A0A0D5C3G0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS02195
gene id: 1580092:NADRNF5_RS02195
uniprot id: A0A0D5C0N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

1580092:NADRNF5 RS06885
gene id: 1580092:NADRNF5_RS06885
uniprot id: A0A0D5C2V5
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS01740
gene id: 1580092:NADRNF5_RS01740
uniprot id: A0A0D5C0W6
names: Caution
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS02250
gene id: 1580092:NADRNF5_RS02250
uniprot id: A0A0D5C1E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1580092:NADRNF5 RS02970
gene id: 1580092:NADRNF5_RS02970
uniprot id: A0A0D5C193
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1580092:NADRNF5 RS09020
gene id: 1580092:NADRNF5_RS09020
uniprot id: A0A0D5C4E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1580092:NADRNF5 RS07015
gene id: 1580092:NADRNF5_RS07015
uniprot id: A0A0D5C2X8
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

1580092:NADRNF5 RS05205
gene id: 1580092:NADRNF5_RS05205
uniprot id: A0A0D5C1T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1580092:NADRNF5 RS01870
gene id: 1580092:NADRNF5_RS01870
uniprot id: A0A0D5BZU7
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

1580092:NADRNF5 RS01235
gene id: 1580092:NADRNF5_RS01235
uniprot id: A0A0D5BZH8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

1580092:NADRNF5 RS00935
gene id: 1580092:NADRNF5_RS00935
uniprot id: A0A0D5C0P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1580092:NADRNF5 RS09695
gene id: 1580092:NADRNF5_RS09695
uniprot id: A0A0D5C5N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1580092:NADRNF5 RS10530
gene id: 1580092:NADRNF5_RS10530
uniprot id: A0A0D5C589
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1580092:NADRNF5 RS00500
gene id: 1580092:NADRNF5_RS00500
uniprot id: A0A0D5C081
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS08515
gene id: 1580092:NADRNF5_RS08515
uniprot id: A0A0D5C4J8
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

1580092:NADRNF5 RS07260
gene id: 1580092:NADRNF5_RS07260
uniprot id: A0A0D5C322
names: Similarity
messages: Belongs to the SUI1 family.

1580092:NADRNF5 RS06745
gene id: 1580092:NADRNF5_RS06745
uniprot id: A0A0D5C3G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1580092:NADRNF5 RS00160
gene id: 1580092:NADRNF5_RS00160
uniprot id: A0A0D5BZ32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS08475
gene id: 1580092:NADRNF5_RS08475
uniprot id: A0A0D5C528
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1580092:NADRNF5 RS09565
gene id: 1580092:NADRNF5_RS09565
uniprot id: A0A0D5C5N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

1580092:NADRNF5 RS09605
gene id: 1580092:NADRNF5_RS09605
uniprot id: A0A0D5C5L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1580092:NADRNF5 RS07095
gene id: 1580092:NADRNF5_RS07095
uniprot id: A0A0D5C2Z4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1580092:NADRNF5 RS00720
gene id: 1580092:NADRNF5_RS00720
uniprot id: A0A0D5C0C7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1580092:NADRNF5 RS01580
gene id: 1580092:NADRNF5_RS01580
uniprot id: A0A0D5C0T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

1580092:NADRNF5 RS00915
gene id: 1580092:NADRNF5_RS00915
uniprot id: A0A0D5C0N7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

1580092:NADRNF5 RS09185
gene id: 1580092:NADRNF5_RS09185
uniprot id: A0A0D5C5E6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1580092:NADRNF5 RS03005
gene id: 1580092:NADRNF5_RS03005
uniprot id: A0A0D5C1X5
names: Similarity
messages: Belongs to the peptidase T1A family.

1580092:NADRNF5 RS00575
gene id: 1580092:NADRNF5_RS00575
uniprot id: A0A0D5BZT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

1580092:NADRNF5 RS05215
gene id: 1580092:NADRNF5_RS05215
uniprot id: A0A0D5C207
names: Similarity
messages: Belongs to the TrpC family.

1580092:NADRNF5 RS05210
gene id: 1580092:NADRNF5_RS05210
uniprot id: A0A0D5C365
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1580092:NADRNF5 RS00520
gene id: 1580092:NADRNF5_RS00520
uniprot id: A0A0D5BZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-3 family.
messages: Membrane

1580092:NADRNF5 RS06535
gene id: 1580092:NADRNF5_RS06535
uniprot id: A0A0D5C2M8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1580092:NADRNF5 RS08470
gene id: 1580092:NADRNF5_RS08470
uniprot id: A0A0D5C3T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1580092:NADRNF5 RS03965
gene id: 1580092:NADRNF5_RS03965
uniprot id: A0A0D5C1T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1580092:NADRNF5 RS07730
gene id: 1580092:NADRNF5_RS07730
uniprot id: A0A0D5C4P8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1580092:NADRNF5 RS08440
gene id: 1580092:NADRNF5_RS08440
uniprot id: A0A0D5C4I5
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS02315
gene id: 1580092:NADRNF5_RS02315
uniprot id: A0A0D5C038
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1580092:NADRNF5 RS09870
gene id: 1580092:NADRNF5_RS09870
uniprot id: A0A0D5C5A5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1580092:NADRNF5 RS01650
gene id: 1580092:NADRNF5_RS01650
uniprot id: A0A0D5C129
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1580092:NADRNF5 RS01300
gene id: 1580092:NADRNF5_RS01300
uniprot id: A0A0D5BZT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1580092:NADRNF5 RS02380
gene id: 1580092:NADRNF5_RS02380
uniprot id: A0A0D5C0D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1580092:NADRNF5 RS00295
gene id: 1580092:NADRNF5_RS00295
uniprot id: A0A0D5C009
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1580092:NADRNF5 RS01350
gene id: 1580092:NADRNF5_RS01350
uniprot id: A0A0D5BZU2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

1580092:NADRNF5 RS01640
gene id: 1580092:NADRNF5_RS01640
uniprot id: A0A0D5C0E0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1580092:NADRNF5 RS06055
gene id: 1580092:NADRNF5_RS06055
uniprot id: A0A0D5C3I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1580092:NADRNF5 RS07125
gene id: 1580092:NADRNF5_RS07125
uniprot id: A0A0D5C4A0
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1580092:NADRNF5 RS02020
gene id: 1580092:NADRNF5_RS02020
uniprot id: A0A0D5C121
names: Subcellular Location Annotation
messages: Nucleus

1580092:NADRNF5 RS10170
gene id: 1580092:NADRNF5_RS10170
uniprot id: A0A0D5C523
names: Similarity
messages: Belongs to the NAD synthetase family.

1580092:NADRNF5 RS02980
gene id: 1580092:NADRNF5_RS02980
uniprot id: A0A0D5C1X0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1580092:NADRNF5 RS10610
gene id: 1580092:NADRNF5_RS10610
uniprot id: A0A0D5C5A3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1580092:NADRNF5 RS10510
gene id: 1580092:NADRNF5_RS10510
uniprot id: A0A0D5C653
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1580092:NADRNF5 RS02580
gene id: 1580092:NADRNF5_RS02580
uniprot id: A0A0D5C1L7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1580092:NADRNF5 RS00760
gene id: 1580092:NADRNF5_RS00760
uniprot id: A0A0D5BZI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1580092:NADRNF5 RS09205
gene id: 1580092:NADRNF5_RS09205
uniprot id: A0A0D5C4H5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1580092:NADRNF5 RS01610
gene id: 1580092:NADRNF5_RS01610
uniprot id: A0A0D5C0U1
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1580092:NADRNF5 RS04810
gene id: 1580092:NADRNF5_RS04810
uniprot id: A0A0D5C2Q2
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

1580092:NADRNF5 RS01025
gene id: 1580092:NADRNF5_RS01025
uniprot id: A0A0D5C031
names: Subunit
messages: Homotrimer.

1580092:NADRNF5 RS10360
gene id: 1580092:NADRNF5_RS10360
uniprot id: A0A0D5C5P0
names: Similarity
messages: Belongs to the DtxR/MntR family.

1580092:NADRNF5 RS04275
gene id: 1580092:NADRNF5_RS04275
uniprot id: A0A0D5C1A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1580092:NADRNF5 RS08995
gene id: 1580092:NADRNF5_RS08995
uniprot id: A0A0D5C5A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

1580092:NADRNF5 RS03200
gene id: 1580092:NADRNF5_RS03200
uniprot id: A0A0D5C1E1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS00440
gene id: 1580092:NADRNF5_RS00440
uniprot id: A0A0D5C0E8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS03145
gene id: 1580092:NADRNF5_RS03145
uniprot id: A0A0D5C1U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

1580092:NADRNF5 RS00770
gene id: 1580092:NADRNF5_RS00770
uniprot id: A0A0D5BZY4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

1580092:NADRNF5 RS08315
gene id: 1580092:NADRNF5_RS08315
uniprot id: A0A0D5C4G6
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

1580092:NADRNF5 RS03955
gene id: 1580092:NADRNF5_RS03955
uniprot id: A0A0D5C1B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1580092:NADRNF5 RS08465
gene id: 1580092:NADRNF5_RS08465
uniprot id: A0A0D5C4J0
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

1580092:NADRNF5 RS09355
gene id: 1580092:NADRNF5_RS09355
uniprot id: A0A0D5C5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1580092:NADRNF5 RS07850
gene id: 1580092:NADRNF5_RS07850
uniprot id: A0A0D5C4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

1580092:NADRNF5 RS00270
gene id: 1580092:NADRNF5_RS00270
uniprot id: A0A0D5BZZ8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1580092:NADRNF5 RS10150
gene id: 1580092:NADRNF5_RS10150
uniprot id: A0A0D5C5Z3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1580092:NADRNF5 RS08905
gene id: 1580092:NADRNF5_RS08905
uniprot id: A0A0D5C419
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1580092:NADRNF5 RS03230
gene id: 1580092:NADRNF5_RS03230
uniprot id: A0A0D5C0Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1580092:NADRNF5 RS00890
gene id: 1580092:NADRNF5_RS00890
uniprot id: A0A0D5C0N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1580092:NADRNF5 RS03300
gene id: 1580092:NADRNF5_RS03300
uniprot id: A0A0D5C0Z5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1580092:NADRNF5 RS07905
gene id: 1580092:NADRNF5_RS07905
uniprot id: A0A0D5C4S8
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

1580092:NADRNF5 RS04230
gene id: 1580092:NADRNF5_RS04230
uniprot id: A0A0D5C1X6
names: Similarity
messages: Belongs to the peptidase U62 family.

1580092:NADRNF5 RS08460
gene id: 1580092:NADRNF5_RS08460
uniprot id: A0A0D5C4Y8
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

1580092:NADRNF5 RS08520
gene id: 1580092:NADRNF5_RS08520
uniprot id: A0A0D5C3U5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

1580092:NADRNF5 RS08255
gene id: 1580092:NADRNF5_RS08255
uniprot id: A0A0D5C3Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1580092:NADRNF5 RS07920
gene id: 1580092:NADRNF5_RS07920
uniprot id: A0A0D5C492
names: Similarity
messages: Belongs to the TFIIB family.

1580092:NADRNF5 RS06950
gene id: 1580092:NADRNF5_RS06950
uniprot id: A0A0D5C416
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1580092:NADRNF5 RS04335
gene id: 1580092:NADRNF5_RS04335
uniprot id: A0A0D5C1J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1580092:NADRNF5 RS00125
gene id: 1580092:NADRNF5_RS00125
uniprot id: A0A0D5BYU9
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS01320
gene id: 1580092:NADRNF5_RS01320
uniprot id: A0A0D5C0W7
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

1580092:NADRNF5 RS02965
gene id: 1580092:NADRNF5_RS02965
uniprot id: A0A0D5C1Q9
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1580092:NADRNF5 RS00740
gene id: 1580092:NADRNF5_RS00740
uniprot id: A0A0D5BZI1
names: Similarity
messages: Belongs to the peptidase M24B family.

1580092:NADRNF5 RS07160
gene id: 1580092:NADRNF5_RS07160
uniprot id: A0A0D5C457
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

1580092:NADRNF5 RS06075
gene id: 1580092:NADRNF5_RS06075
uniprot id: A0A0D5C2M3
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

1580092:NADRNF5 RS07210
gene id: 1580092:NADRNF5_RS07210
uniprot id: A0A0D5C468
names: Similarity
messages: Belongs to the UPF0215 family.

1580092:NADRNF5 RS00920
gene id: 1580092:NADRNF5_RS00920
uniprot id: A0A0D5BZL6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

1580092:NADRNF5 RS04145
gene id: 1580092:NADRNF5_RS04145
uniprot id: A0A0D5C1F2
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

1580092:NADRNF5 RS10020
gene id: 1580092:NADRNF5_RS10020
uniprot id: A0A0D5C5V3
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS03125
gene id: 1580092:NADRNF5_RS03125
uniprot id: A0A0D5C1C6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1580092:NADRNF5 RS07965
gene id: 1580092:NADRNF5_RS07965
uniprot id: A0A0D5C4Q3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1580092:NADRNF5 RS01770
gene id: 1580092:NADRNF5_RS01770
uniprot id: A0A0D5C0F9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

1580092:NADRNF5 RS06385
gene id: 1580092:NADRNF5_RS06385
uniprot id: A0A0D5C3V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1580092:NADRNF5 RS08330
gene id: 1580092:NADRNF5_RS08330
uniprot id: A0A0D5C406
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1580092:NADRNF5 RS02435
gene id: 1580092:NADRNF5_RS02435
uniprot id: A0A0D5C0T7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1580092:NADRNF5 RS03150
gene id: 1580092:NADRNF5_RS03150
uniprot id: A0A0D5C1D1
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).

1580092:NADRNF5 RS09110
gene id: 1580092:NADRNF5_RS09110
uniprot id: A0A0D5C4W4
names: Subunit
messages: Homotrimer.

1580092:NADRNF5 RS05110
gene id: 1580092:NADRNF5_RS05110
uniprot id: A0A0D5C337
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

1580092:NADRNF5 RS00905
gene id: 1580092:NADRNF5_RS00905
uniprot id: A0A0D5C013
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1580092:NADRNF5 RS10620
gene id: 1580092:NADRNF5_RS10620
uniprot id: A0A0D5C5T3
names: Similarity
messages: Belongs to the prespore-cell-inducing factor family.

1580092:NADRNF5 RS00765
gene id: 1580092:NADRNF5_RS00765
uniprot id: A0A0D5C0D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

1580092:NADRNF5 RS09465
gene id: 1580092:NADRNF5_RS09465
uniprot id: A0A0D5C4L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1580092:NADRNF5 RS04880
gene id: 1580092:NADRNF5_RS04880
uniprot id: A0A0D5C2R7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1580092:NADRNF5 RS10210
gene id: 1580092:NADRNF5_RS10210
uniprot id: A0A0D5C4T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1580092:NADRNF5 RS02450
gene id: 1580092:NADRNF5_RS02450
uniprot id: A0A0D5C0E5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1580092:NADRNF5 RS01545
gene id: 1580092:NADRNF5_RS01545
uniprot id: A0A0D5C108
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

1580092:NADRNF5 RS02085
gene id: 1580092:NADRNF5_RS02085
uniprot id: A0A0D5BZY9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1580092:NADRNF5 RS02120
gene id: 1580092:NADRNF5_RS02120
uniprot id: A0A0D5C141
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1580092:NADRNF5 RS06045
gene id: 1580092:NADRNF5_RS06045
uniprot id: A0A0D5C3N6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1580092:NADRNF5 RS05390
gene id: 1580092:NADRNF5_RS05390
uniprot id: A0A0D5C2Q6
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS01620
gene id: 1580092:NADRNF5_RS01620
uniprot id: A0A0D5BZP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1580092:NADRNF5 RS10315
gene id: 1580092:NADRNF5_RS10315
uniprot id: A0A0D5C650
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1580092:NADRNF5 RS09055
gene id: 1580092:NADRNF5_RS09055
uniprot id: A0A0D5C4V2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1580092:NADRNF5 RS03015
gene id: 1580092:NADRNF5_RS03015
uniprot id: A0A0D5C1R8
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

1580092:NADRNF5 RS04330
gene id: 1580092:NADRNF5_RS04330
uniprot id: A0A0D5C2M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1580092:NADRNF5 RS03160
gene id: 1580092:NADRNF5_RS03160
uniprot id: A0A0D5C209
names: Similarity
messages: Belongs to the diphthine synthase family.

1580092:NADRNF5 RS06065
gene id: 1580092:NADRNF5_RS06065
uniprot id: A0A0D5C2D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1580092:NADRNF5 RS08580
gene id: 1580092:NADRNF5_RS08580
uniprot id: A0A0D5C509
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1580092:NADRNF5 RS03285
gene id: 1580092:NADRNF5_RS03285
uniprot id: A0A0D5C1F6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

1580092:NADRNF5 RS04060
gene id: 1580092:NADRNF5_RS04060
uniprot id: A0A0D5C165
names: Similarity
messages: Belongs to the citrate synthase family.

1580092:NADRNF5 RS10405
gene id: 1580092:NADRNF5_RS10405
uniprot id: A0A0D5C5P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1580092:NADRNF5 RS00960
gene id: 1580092:NADRNF5_RS00960
uniprot id: A0A0D5C0P8
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS01635
gene id: 1580092:NADRNF5_RS01635
uniprot id: A0A0D5C0U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1580092:NADRNF5 RS05565
gene id: 1580092:NADRNF5_RS05565
uniprot id: A0A0D5C2U7
names: Similarity
messages: Belongs to the glutaredoxin family.

1580092:NADRNF5 RS05605
gene id: 1580092:NADRNF5_RS05605
uniprot id: A0A0D5C2D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1580092:NADRNF5 RS00375
gene id: 1580092:NADRNF5_RS00375
uniprot id: A0A0D5BZN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

1580092:NADRNF5 RS09600
gene id: 1580092:NADRNF5_RS09600
uniprot id: A0A0D5C4N5
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

1580092:NADRNF5 RS08845
gene id: 1580092:NADRNF5_RS08845
uniprot id: A0A0D5C564
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS05060
gene id: 1580092:NADRNF5_RS05060
uniprot id: A0A0D5C328
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1580092:NADRNF5 RS05655
gene id: 1580092:NADRNF5_RS05655
uniprot id: A0A0D5C2E4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1580092:NADRNF5 RS05150
gene id: 1580092:NADRNF5_RS05150
uniprot id: A0A0D5C2H2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Binds 2 Mg(2+) or Mn(2+) ions per subunit.
messages: Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS00465
gene id: 1580092:NADRNF5_RS00465
uniprot id: A0A0D5C0F7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-64 and Arg-67) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

1580092:NADRNF5 RS06565
gene id: 1580092:NADRNF5_RS06565
uniprot id: A0A0D5C3Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1580092:NADRNF5 RS06015
gene id: 1580092:NADRNF5_RS06015
uniprot id: A0A0D5C2C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

1580092:NADRNF5 RS05375
gene id: 1580092:NADRNF5_RS05375
uniprot id: A0A0D5C3B3
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS01765
gene id: 1580092:NADRNF5_RS01765
uniprot id: A0A0D5C0X1
names: Similarity
messages: Belongs to the HAM1 NTPase family.

1580092:NADRNF5 RS04190
gene id: 1580092:NADRNF5_RS04190
uniprot id: A0A0D5C2K2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS02310
gene id: 1580092:NADRNF5_RS02310
uniprot id: A0A0D5C0R2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1580092:NADRNF5 RS01245
gene id: 1580092:NADRNF5_RS01245
uniprot id: A0A0D5C0V2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1580092:NADRNF5 RS09310
gene id: 1580092:NADRNF5_RS09310
uniprot id: A0A0D5C5J1
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS01055
gene id: 1580092:NADRNF5_RS01055
uniprot id: A0A0D5BZE4
names: Similarity
messages: Belongs to the glutaredoxin family.

1580092:NADRNF5 RS08380
gene id: 1580092:NADRNF5_RS08380
uniprot id: A0A0D5C4X6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1580092:NADRNF5 RS09490
gene id: 1580092:NADRNF5_RS09490
uniprot id: A0A0D5C4L6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1580092:NADRNF5 RS00470
gene id: 1580092:NADRNF5_RS00470
uniprot id: A0A0D5BZC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1580092:NADRNF5 RS05610
gene id: 1580092:NADRNF5_RS05610
uniprot id: A0A0D5C3A1
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.

1580092:NADRNF5 RS05945
gene id: 1580092:NADRNF5_RS05945
uniprot id: A0A0D5C3L7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS04745
gene id: 1580092:NADRNF5_RS04745
uniprot id: A0A0D5C1K4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS00845
gene id: 1580092:NADRNF5_RS00845
uniprot id: A0A0D5C0M4
names: Caution
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS05915
gene id: 1580092:NADRNF5_RS05915
uniprot id: A0A0D5C309
names: Subcellular Location Annotation
messages: Cytoplasm

1580092:NADRNF5 RS01190
gene id: 1580092:NADRNF5_RS01190
uniprot id: A0A0D5BZG9
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS06600
gene id: 1580092:NADRNF5_RS06600
uniprot id: A0A0D5C3D7
names: Similarity
messages: Belongs to the UPF0045 family.

1580092:NADRNF5 RS10570
gene id: 1580092:NADRNF5_RS10570
uniprot id: A0A0D5C502
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1580092:NADRNF5 RS01860
gene id: 1580092:NADRNF5_RS01860
uniprot id: A0A0D5C0Y8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

1580092:NADRNF5 RS01880
gene id: 1580092:NADRNF5_RS01880
uniprot id: A0A0D5C039
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

1580092:NADRNF5 RS08490
gene id: 1580092:NADRNF5_RS08490
uniprot id: A0A0D5C4J3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1580092:NADRNF5 RS04765
gene id: 1580092:NADRNF5_RS04765
uniprot id: A0A0D5C278
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1580092:NADRNF5 RS10365
gene id: 1580092:NADRNF5_RS10365
uniprot id: A0A0D5C660
names: Similarity
messages: Belongs to the UPF0047 family.

1580092:NADRNF5 RS05930
gene id: 1580092:NADRNF5_RS05930
uniprot id: A0A0D5C2J6
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1580092:NADRNF5 RS05005
gene id: 1580092:NADRNF5_RS05005
uniprot id: A0A0D5C319
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS08990
gene id: 1580092:NADRNF5_RS08990
uniprot id: A0A0D5C4D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

1580092:NADRNF5 RS02000
gene id: 1580092:NADRNF5_RS02000
uniprot id: A0A0D5C114
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1580092:NADRNF5 RS00855
gene id: 1580092:NADRNF5_RS00855
uniprot id: A0A0D5C0F1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS08525
gene id: 1580092:NADRNF5_RS08525
uniprot id: A0A0D5C539
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS08830
gene id: 1580092:NADRNF5_RS08830
uniprot id: A0A0D5C4Q0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1580092:NADRNF5 RS08530
gene id: 1580092:NADRNF5_RS08530
uniprot id: A0A0D5C441
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

1580092:NADRNF5 RS09375
gene id: 1580092:NADRNF5_RS09375
uniprot id: A0A0D5C4K0
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS06040
gene id: 1580092:NADRNF5_RS06040
uniprot id: A0A0D5C2D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

1580092:NADRNF5 RS07465
gene id: 1580092:NADRNF5_RS07465
uniprot id: A0A0D5C4C7
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS08740
gene id: 1580092:NADRNF5_RS08740
uniprot id: A0A0D5C3Y9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1580092:NADRNF5 RS05140
gene id: 1580092:NADRNF5_RS05140
uniprot id: A0A0D5C348
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS03410
gene id: 1580092:NADRNF5_RS03410
uniprot id: A0A0D5C1I3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

1580092:NADRNF5 RS07725
gene id: 1580092:NADRNF5_RS07725
uniprot id: A0A0D5C3E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

1580092:NADRNF5 RS01305
gene id: 1580092:NADRNF5_RS01305
uniprot id: A0A0D5C0N5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1580092:NADRNF5 RS01035
gene id: 1580092:NADRNF5_RS01035
uniprot id: A0A0D5C0R0
names: Similarity
messages: Belongs to the glutaredoxin family.

1580092:NADRNF5 RS07085
gene id: 1580092:NADRNF5_RS07085
uniprot id: A0A0D5C442
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1580092:NADRNF5 RS02410
gene id: 1580092:NADRNF5_RS02410
uniprot id: A0A0D5C196
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1580092:NADRNF5 RS07930
gene id: 1580092:NADRNF5_RS07930
uniprot id: A0A0D5C4T6
names: Similarity
messages: Belongs to the UPF0235 family.

1580092:NADRNF5 RS07610
gene id: 1580092:NADRNF5_RS07610
uniprot id: A0A0D5C4I7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1580092:NADRNF5 RS01260
gene id: 1580092:NADRNF5_RS01260
uniprot id: A0A0D5C071
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

1580092:NADRNF5 RS03805
gene id: 1580092:NADRNF5_RS03805
uniprot id: A0A0D5C186
names: Cofactor
messages: Binds 1 copper ion per subunit.

1580092:NADRNF5 RS08485
gene id: 1580092:NADRNF5_RS08485
uniprot id: A0A0D5C4Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1580092:NADRNF5 RS09320
gene id: 1580092:NADRNF5_RS09320
uniprot id: A0A0D5C5H0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS05560
gene id: 1580092:NADRNF5_RS05560
uniprot id: A0A0D5C393
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

1580092:NADRNF5 RS07285
gene id: 1580092:NADRNF5_RS07285
uniprot id: A0A0D5C4D6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS06025
gene id: 1580092:NADRNF5_RS06025
uniprot id: A0A0D5C2L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

1580092:NADRNF5 RS05220
gene id: 1580092:NADRNF5_RS05220
uniprot id: A0A0D5C2Z5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS10380
gene id: 1580092:NADRNF5_RS10380
uniprot id: A0A0D5C5P2
names: Similarity
messages: Belongs to the CutA family.

1580092:NADRNF5 RS07890
gene id: 1580092:NADRNF5_RS07890
uniprot id: A0A0D5C4P2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1580092:NADRNF5 RS00480
gene id: 1580092:NADRNF5_RS00480
uniprot id: A0A0D5BZS1
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1580092:NADRNF5 RS05145
gene id: 1580092:NADRNF5_RS05145
uniprot id: A0A0D5C1Z2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1580092:NADRNF5 RS05635
gene id: 1580092:NADRNF5_RS05635
uniprot id: A0A0D5C3A6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1580092:NADRNF5 RS10470
gene id: 1580092:NADRNF5_RS10470
uniprot id: A0A0D5C5Q4
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS05540
gene id: 1580092:NADRNF5_RS05540
uniprot id: A0A0D5C2U1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS04715
gene id: 1580092:NADRNF5_RS04715
uniprot id: A0A0D5C2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1580092:NADRNF5 RS01130
gene id: 1580092:NADRNF5_RS01130
uniprot id: A0A0D5C0K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

1580092:NADRNF5 RS09360
gene id: 1580092:NADRNF5_RS09360
uniprot id: A0A0D5C504
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS09190
gene id: 1580092:NADRNF5_RS09190
uniprot id: A0A0D5C4X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS09390
gene id: 1580092:NADRNF5_RS09390
uniprot id: A0A0D5C5H8
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

1580092:NADRNF5 RS00715
gene id: 1580092:NADRNF5_RS00715
uniprot id: A0A0D5BZH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

1580092:NADRNF5 RS01480
gene id: 1580092:NADRNF5_RS01480
uniprot id: A0A0D5BZM6
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

1580092:NADRNF5 RS10205
gene id: 1580092:NADRNF5_RS10205
uniprot id: A0A0D5C5K2
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS10355
gene id: 1580092:NADRNF5_RS10355
uniprot id: A0A0D5C626
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

1580092:NADRNF5 RS09705
gene id: 1580092:NADRNF5_RS09705
uniprot id: A0A0D5C571
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

1580092:NADRNF5 RS09230
gene id: 1580092:NADRNF5_RS09230
uniprot id: A0A0D5C4I0
names: Similarity
messages: Belongs to the UPF0147 family.

1580092:NADRNF5 RS10120
gene id: 1580092:NADRNF5_RS10120
uniprot id: A0A0D5C505
names: Similarity
messages: Belongs to the PGI/PMI family.

1580092:NADRNF5 RS08480
gene id: 1580092:NADRNF5_RS08480
uniprot id: A0A0D5C431
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1580092:NADRNF5 RS10135
gene id: 1580092:NADRNF5_RS10135
uniprot id: A0A0D5C4R8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1580092:NADRNF5 RS09350
gene id: 1580092:NADRNF5_RS09350
uniprot id: A0A0D5C4J6
names: Subcellular Location Annotation
messages: Membrane

1580092:NADRNF5 RS08235
gene id: 1580092:NADRNF5_RS08235
uniprot id: A0A0D5C4U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS08060
gene id: 1580092:NADRNF5_RS08060
uniprot id: A0A0D5C4V8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1580092:NADRNF5 RS00370
gene id: 1580092:NADRNF5_RS00370
uniprot id: A0A0D5C027
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1580092:NADRNF5 RS03690
gene id: 1580092:NADRNF5_RS03690
uniprot id: A0A0D5C1M7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1580092:NADRNF5 RS07250
gene id: 1580092:NADRNF5_RS07250
uniprot id: A0A0D5C479
names: Caution
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1580092:NADRNF5 RS09570
gene id: 1580092:NADRNF5_RS09570
uniprot id: A0A0D5C4N0
names: Similarity
messages: Belongs to the MCM family.

1580092:NADRNF5 RS08290
gene id: 1580092:NADRNF5_RS08290
uniprot id: A0A0D5C4G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

1580092:NADRNF5 RS04135
gene id: 1580092:NADRNF5_RS04135
uniprot id: A0A0D5C179
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1580092:NADRNF5 RS09210
gene id: 1580092:NADRNF5_RS09210
uniprot id: A0A0D5C5F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

1580092:NADRNF5 RS00455
gene id: 1580092:NADRNF5_RS00455
uniprot id: A0A0D5BZR0
names: Similarity
messages: Belongs to the UPF0201 family.

1580092:NADRNF5 RS10035
gene id: 1580092:NADRNF5_RS10035
uniprot id: A0A0D5C5X3
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 2 family.

1580092:NADRNF5 RS03215
gene id: 1580092:NADRNF5_RS03215
uniprot id: A0A0D5C0X9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS10605
gene id: 1580092:NADRNF5_RS10605
uniprot id: A0A0D5C697
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

1580092:NADRNF5 RS04915
gene id: 1580092:NADRNF5_RS04915
uniprot id: A0A0D5C1U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm

1580092:NADRNF5 RS01825
gene id: 1580092:NADRNF5_RS01825
uniprot id: A0A0D5BZT3
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

1580092:NADRNF5 RS07910
gene id: 1580092:NADRNF5_RS07910
uniprot id: A0A0D5C3S3
names: Subcellular Location Annotation
messages: Cytoplasm

1580092:NADRNF5 RS09125
gene id: 1580092:NADRNF5_RS09125
uniprot id: A0A0D5C4G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1580092:NADRNF5 RS05195
gene id: 1580092:NADRNF5_RS05195
uniprot id: A0A0D5C2Y8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS08910
gene id: 1580092:NADRNF5_RS08910
uniprot id: A0A0D5C5C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1580092:NADRNF5 RS03470
gene id: 1580092:NADRNF5_RS03470
uniprot id: A0A0D5C259
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1580092:NADRNF5 RS02345
gene id: 1580092:NADRNF5_RS02345
uniprot id: A0A0D5C1G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1580092:NADRNF5 RS02125
gene id: 1580092:NADRNF5_RS02125
uniprot id: A0A0D5C0M5
names: Similarity
messages: Belongs to the PDCD5 family.

1580092:NADRNF5 RS08185
gene id: 1580092:NADRNF5_RS08185
uniprot id: A0A0D5C4T9
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1580092:NADRNF5 RS04895
gene id: 1580092:NADRNF5_RS04895
uniprot id: A0A0D5C1U5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1580092:NADRNF5 RS01625
gene id: 1580092:NADRNF5_RS01625
uniprot id: A0A0D5C124
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1580092:NADRNF5 RS04510
gene id: 1580092:NADRNF5_RS04510
uniprot id: A0A0D5C232
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1580092:NADRNF5 RS07815
gene id: 1580092:NADRNF5_RS07815
uniprot id: A0A0D5C4M7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

1580092:NADRNF5 RS10445
gene id: 1580092:NADRNF5_RS10445
uniprot id: A0A0D5C673
names: Function
names: Similarity
messages: Belongs to the GrpE family.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1580092:NADRNF5 RS09140
gene id: 1580092:NADRNF5_RS09140
uniprot id: A0A0D5C463
names: Similarity
messages: Belongs to the UPF0284 family.

1580092:NADRNF5 RS08300
gene id: 1580092:NADRNF5_RS08300
uniprot id: A0A0D5C4Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1580092:NADRNF5 RS01495
gene id: 1580092:NADRNF5_RS01495
uniprot id: A0A0D5C0R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1580092:NADRNF5 RS04870
gene id: 1580092:NADRNF5_RS04870
uniprot id: A0A0D5C2Z1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1580092:NADRNF5 RS08430
gene id: 1580092:NADRNF5_RS08430
uniprot id: A0A0D5C422
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1580092:NADRNF5 RS00155
gene id: 1580092:NADRNF5_RS00155
uniprot id: A0A0D5C076
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1580092:NADRNF5 RS05925
gene id: 1580092:NADRNF5_RS05925
uniprot id: A0A0D5C3L2
names: Similarity
messages: Belongs to the glutaredoxin family.

1580092:NADRNF5 RS03170
gene id: 1580092:NADRNF5_RS03170
uniprot id: A0A0D5C1U7
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

1580092:NADRNF5 RS08435
gene id: 1580092:NADRNF5_RS08435
uniprot id: A0A0D5C4Y2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1580092:NADRNF5 RS03945
gene id: 1580092:NADRNF5_RS03945
uniprot id: A0A0D5C143
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

1580092:NADRNF5 RS04925
gene id: 1580092:NADRNF5_RS04925
uniprot id: A0A0D5C2B6
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1580092:NADRNF5 RS01565
gene id: 1580092:NADRNF5_RS01565
uniprot id: A0A0D5BZP0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1580092:NADRNF5 RS02350
gene id: 1580092:NADRNF5_RS02350
uniprot id: A0A0D5C0C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1580092:NADRNF5 RS06020
gene id: 1580092:NADRNF5_RS06020
uniprot id: A0A0D5C3N2
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

1580092:NADRNF5 RS08505
gene id: 1580092:NADRNF5_RS08505
uniprot id: A0A0D5C435
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

1580092:NADRNF5 RS08735
gene id: 1580092:NADRNF5_RS08735
uniprot id: A0A0D5C4N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1580092:NADRNF5 RS09175
gene id: 1580092:NADRNF5_RS09175
uniprot id: A0A0D5C5H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1580092:NADRNF5 RS00345
gene id: 1580092:NADRNF5_RS00345
uniprot id: A0A0D5C019
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

1580092:NADRNF5 RS07525
gene id: 1580092:NADRNF5_RS07525
uniprot id: A0A0D5C4I1
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1580092:NADRNF5 RS10400
gene id: 1580092:NADRNF5_RS10400
uniprot id: A0A0D5C634
names: Similarity
messages: Belongs to the acylphosphatase family.

1580092:NADRNF5 RS01310
gene id: 1580092:NADRNF5_RS01310
uniprot id: A0A0D5C080
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

1580092:NADRNF5 RS00120
gene id: 1580092:NADRNF5_RS00120
uniprot id: A0A0D5BZH3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1580092:NADRNF5 RS04855
gene id: 1580092:NADRNF5_RS04855
uniprot id: A0A0D5C1T7
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1580092:NADRNF5 RS09180
gene id: 1580092:NADRNF5_RS09180
uniprot id: A0A0D5C4H2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1580092:NADRNF5 RS07840
gene id: 1580092:NADRNF5_RS07840
uniprot id: A0A0D5C476
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1580092:NADRNF5 RS10500
gene id: 1580092:NADRNF5_RS10500
uniprot id: A0A0D5C681
names: Similarity
messages: Belongs to the AdoMet synthase family.

1580092:NADRNF5 RS01515
gene id: 1580092:NADRNF5_RS01515
uniprot id: A0A0D5C104
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1580092:NADRNF5 RS09710
gene id: 1580092:NADRNF5_RS09710
uniprot id: A0A0D5C4G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.