1579979:WM2015 RS05385
gene id: 1579979:WM2015_RS05385
uniprot id: A0A0K0XUZ6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1579979:WM2015 RS01290
gene id: 1579979:WM2015_RS01290
uniprot id: A0A0K0XSI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1579979:WM2015 RS08585
gene id: 1579979:WM2015_RS08585
uniprot id: A0A0K0XWQ4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1579979:WM2015 RS05135
gene id: 1579979:WM2015_RS05135
uniprot id: A0A0K0XUL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1579979:WM2015 RS08245
gene id: 1579979:WM2015_RS08245
uniprot id: A0A0K0XWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1579979:WM2015 RS07170
gene id: 1579979:WM2015_RS07170
uniprot id: A0A0K0XVU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1579979:WM2015 RS10875
gene id: 1579979:WM2015_RS10875
uniprot id: A0A0K0XXT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1579979:WM2015 RS01840
gene id: 1579979:WM2015_RS01840
uniprot id: A0A0K0XSW3
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1579979:WM2015 RS07980
gene id: 1579979:WM2015_RS07980
uniprot id: A0A0K0XW95
names: Subunit
messages: Homodimer.

1579979:WM2015 RS16185
gene id: 1579979:WM2015_RS16185
uniprot id: A0A0K0XT13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1579979:WM2015 RS08455
gene id: 1579979:WM2015_RS08455
uniprot id: A0A0K0XWI1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1579979:WM2015 RS11475
gene id: 1579979:WM2015_RS11475
uniprot id: A0A0K0XY83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1579979:WM2015 RS10685
gene id: 1579979:WM2015_RS10685
uniprot id: A0A0K0XXW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1579979:WM2015 RS02820
gene id: 1579979:WM2015_RS02820
uniprot id: A0A0K0XTA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1579979:WM2015 RS09270
gene id: 1579979:WM2015_RS09270
uniprot id: A0A0K0XWY5
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS00505
gene id: 1579979:WM2015_RS00505
uniprot id: A0A0K0XS25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1579979:WM2015 RS10015
gene id: 1579979:WM2015_RS10015
uniprot id: A0A0K0XXC0
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1579979:WM2015 RS05120
gene id: 1579979:WM2015_RS05120
uniprot id: A0A0K0XUV0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS00205
gene id: 1579979:WM2015_RS00205
uniprot id: A0A0K0XS35
names: Similarity
messages: Belongs to the group II decarboxylase family.

1579979:WM2015 RS00570
gene id: 1579979:WM2015_RS00570
uniprot id: A0A0K0XSA6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1579979:WM2015 RS06950
gene id: 1579979:WM2015_RS06950
uniprot id: A0A0K0XVU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS05230
gene id: 1579979:WM2015_RS05230
uniprot id: A0A0K0XUQ9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1579979:WM2015 RS03220
gene id: 1579979:WM2015_RS03220
uniprot id: A0A0K0XTL0
names: Similarity
messages: Belongs to the BolA/IbaG family.

1579979:WM2015 RS11720
gene id: 1579979:WM2015_RS11720
uniprot id: A0A0K0XYC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1579979:WM2015 RS08995
gene id: 1579979:WM2015_RS08995
uniprot id: A0A0K0XWU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1579979:WM2015 RS07935
gene id: 1579979:WM2015_RS07935
uniprot id: A0A0K0XWE3
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1579979:WM2015 RS05250
gene id: 1579979:WM2015_RS05250
uniprot id: A0A0K0XUX2
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1579979:WM2015 RS10450
gene id: 1579979:WM2015_RS10450
uniprot id: A0A0K0XXM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1579979:WM2015 RS12255
gene id: 1579979:WM2015_RS12255
uniprot id: A0A0K0XYN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1579979:WM2015 RS12280
gene id: 1579979:WM2015_RS12280
uniprot id: A0A0K0XYP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1579979:WM2015 RS02060
gene id: 1579979:WM2015_RS02060
uniprot id: A0A0K0XSU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1579979:WM2015 RS09235
gene id: 1579979:WM2015_RS09235
uniprot id: A0A0K0XX29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1579979:WM2015 RS00815
gene id: 1579979:WM2015_RS00815
uniprot id: A0A0K0XS66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1579979:WM2015 RS10825
gene id: 1579979:WM2015_RS10825
uniprot id: A0A0K0XXV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1579979:WM2015 RS10545
gene id: 1579979:WM2015_RS10545
uniprot id: A0A0K0XXM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1579979:WM2015 RS08650
gene id: 1579979:WM2015_RS08650
uniprot id: A0A0K0XWM7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS05945
gene id: 1579979:WM2015_RS05945
uniprot id: A0A0K0XVA5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1579979:WM2015 RS07805
gene id: 1579979:WM2015_RS07805
uniprot id: A0A0K0XW60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1579979:WM2015 RS06470
gene id: 1579979:WM2015_RS06470
uniprot id: A0A0K0XVG1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1579979:WM2015 RS00010
gene id: 1579979:WM2015_RS00010
uniprot id: A0A0K0XRS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1579979:WM2015 RS08360
gene id: 1579979:WM2015_RS08360
uniprot id: A0A0K0XWH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1579979:WM2015 RS00790
gene id: 1579979:WM2015_RS00790
uniprot id: A0A0K0XS60
names: Similarity
messages: Belongs to the GARS family.

1579979:WM2015 RS05475
gene id: 1579979:WM2015_RS05475
uniprot id: A0A0K0XUX1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1579979:WM2015 RS03035
gene id: 1579979:WM2015_RS03035
uniprot id: A0A0K0XTN6
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1579979:WM2015 RS03730
gene id: 1579979:WM2015_RS03730
uniprot id: A0A0K0XU20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

1579979:WM2015 RS11520
gene id: 1579979:WM2015_RS11520
uniprot id: A0A0K0XY66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1579979:WM2015 RS10115
gene id: 1579979:WM2015_RS10115
uniprot id: A0A0K0XXD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1579979:WM2015 RS06865
gene id: 1579979:WM2015_RS06865
uniprot id: A0A0K0XVK7
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1579979:WM2015 RS01425
gene id: 1579979:WM2015_RS01425
uniprot id: A0A0K0XSI1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1579979:WM2015 RS12010
gene id: 1579979:WM2015_RS12010
uniprot id: A0A0K0XYH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1579979:WM2015 RS14930
gene id: 1579979:WM2015_RS14930
uniprot id: A0A0K0Y071
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1579979:WM2015 RS04985
gene id: 1579979:WM2015_RS04985
uniprot id: A0A0K0XUS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1579979:WM2015 RS08240
gene id: 1579979:WM2015_RS08240
uniprot id: A0A0K0XWI7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1579979:WM2015 RS00840
gene id: 1579979:WM2015_RS00840
uniprot id: A0A0K0XS72
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1579979:WM2015 RS04825
gene id: 1579979:WM2015_RS04825
uniprot id: A0A0K0XUI2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1579979:WM2015 RS13285
gene id: 1579979:WM2015_RS13285
uniprot id: A0A0K0XZ72
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

1579979:WM2015 RS01470
gene id: 1579979:WM2015_RS01470
uniprot id: A0A0K0XSJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1579979:WM2015 RS14025
gene id: 1579979:WM2015_RS14025
uniprot id: A0A0K0XZM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1579979:WM2015 RS10475
gene id: 1579979:WM2015_RS10475
uniprot id: A0A0K0XXN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1579979:WM2015 RS12875
gene id: 1579979:WM2015_RS12875
uniprot id: A0A0K0XYY7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1579979:WM2015 RS03465
gene id: 1579979:WM2015_RS03465
uniprot id: A0A0K0XTN0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS00775
gene id: 1579979:WM2015_RS00775
uniprot id: A0A0K0XSE5
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

1579979:WM2015 RS09165
gene id: 1579979:WM2015_RS09165
uniprot id: A0A0K0XWZ8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1579979:WM2015 RS07225
gene id: 1579979:WM2015_RS07225
uniprot id: A0A0K0XVT7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS07180
gene id: 1579979:WM2015_RS07180
uniprot id: A0A0K0XVY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1579979:WM2015 RS11745
gene id: 1579979:WM2015_RS11745
uniprot id: A0A0K0XYD1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1579979:WM2015 RS10340
gene id: 1579979:WM2015_RS10340
uniprot id: A0A0K0XXK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1579979:WM2015 RS07940
gene id: 1579979:WM2015_RS07940
uniprot id: A0A0K0XWD0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1579979:WM2015 RS11135
gene id: 1579979:WM2015_RS11135
uniprot id: A0A0K0XY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1579979:WM2015 RS00370
gene id: 1579979:WM2015_RS00370
uniprot id: A0A0K0XS33
names: Similarity
messages: Belongs to the peptidase S8 family.

1579979:WM2015 RS14255
gene id: 1579979:WM2015_RS14255
uniprot id: A0A0K0XZV0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1579979:WM2015 RS09780
gene id: 1579979:WM2015_RS09780
uniprot id: A0A0K0XXF9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1579979:WM2015 RS13845
gene id: 1579979:WM2015_RS13845
uniprot id: A0A0K0XZN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1579979:WM2015 RS02750
gene id: 1579979:WM2015_RS02750
uniprot id: A0A0K0XTE3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1579979:WM2015 RS03185
gene id: 1579979:WM2015_RS03185
uniprot id: A0A0K0XTR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

1579979:WM2015 RS13080
gene id: 1579979:WM2015_RS13080
uniprot id: A0A0K0XZ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1579979:WM2015 RS00515
gene id: 1579979:WM2015_RS00515
uniprot id: A0A0K0XS62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1579979:WM2015 RS00525
gene id: 1579979:WM2015_RS00525
uniprot id: A0A0K0XS98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1579979:WM2015 RS09475
gene id: 1579979:WM2015_RS09475
uniprot id: A0A0K0XX38
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1579979:WM2015 RS14960
gene id: 1579979:WM2015_RS14960
uniprot id: A0A0K0Y0D0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1579979:WM2015 RS11310
gene id: 1579979:WM2015_RS11310
uniprot id: A0A0K0XY91
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1579979:WM2015 RS08890
gene id: 1579979:WM2015_RS08890
uniprot id: A0A0K0XWP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1579979:WM2015 RS03340
gene id: 1579979:WM2015_RS03340
uniprot id: A0A0K0XTU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1579979:WM2015 RS14910
gene id: 1579979:WM2015_RS14910
uniprot id: A0A0K0Y0C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1579979:WM2015 RS09965
gene id: 1579979:WM2015_RS09965
uniprot id: A0A0K0XXA8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS01225
gene id: 1579979:WM2015_RS01225
uniprot id: A0A0K0XSM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS09660
gene id: 1579979:WM2015_RS09660
uniprot id: A0A0K0XXB4
names: Similarity
messages: Belongs to the CFA/CMAS family.

1579979:WM2015 RS07950
gene id: 1579979:WM2015_RS07950
uniprot id: A0A0K0XW58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1579979:WM2015 RS00795
gene id: 1579979:WM2015_RS00795
uniprot id: A0A0K0XSB6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1579979:WM2015 RS08215
gene id: 1579979:WM2015_RS08215
uniprot id: A0A0K0XWD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1579979:WM2015 RS02160
gene id: 1579979:WM2015_RS02160
uniprot id: A0A0K0XSZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1579979:WM2015 RS06925
gene id: 1579979:WM2015_RS06925
uniprot id: A0A0K0XVL7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1579979:WM2015 RS08955
gene id: 1579979:WM2015_RS08955
uniprot id: A0A0K0XWX3
names: Similarity
messages: Belongs to the citrate synthase family.

1579979:WM2015 RS13880
gene id: 1579979:WM2015_RS13880
uniprot id: A0A0K0XZJ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1579979:WM2015 RS14260
gene id: 1579979:WM2015_RS14260
uniprot id: A0A0K0XZR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS09145
gene id: 1579979:WM2015_RS09145
uniprot id: A0A0K0XWW1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1579979:WM2015 RS01175
gene id: 1579979:WM2015_RS01175
uniprot id: A0A0K0XSL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1579979:WM2015 RS11580
gene id: 1579979:WM2015_RS11580
uniprot id: A0A0K0XYE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1579979:WM2015 RS11480
gene id: 1579979:WM2015_RS11480
uniprot id: A0A0K0XYC9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1579979:WM2015 RS10855
gene id: 1579979:WM2015_RS10855
uniprot id: A0A0K0XY23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1579979:WM2015 RS03090
gene id: 1579979:WM2015_RS03090
uniprot id: A0A0K0XTI4
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1579979:WM2015 RS14815
gene id: 1579979:WM2015_RS14815
uniprot id: A0A0K0Y025
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1579979:WM2015 RS03310
gene id: 1579979:WM2015_RS03310
uniprot id: A0A0K0XTU1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1579979:WM2015 RS06565
gene id: 1579979:WM2015_RS06565
uniprot id: A0A0K0XVH5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1579979:WM2015 RS15065
gene id: 1579979:WM2015_RS15065
uniprot id: A0A0K0Y072
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1579979:WM2015 RS07645
gene id: 1579979:WM2015_RS07645
uniprot id: A0A0K0XW20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS02810
gene id: 1579979:WM2015_RS02810
uniprot id: A0A0K0XTJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS00575
gene id: 1579979:WM2015_RS00575
uniprot id: A0A0K0XSA9
names: Similarity
messages: Belongs to the UPF0758 family.

1579979:WM2015 RS06750
gene id: 1579979:WM2015_RS06750
uniprot id: A0A0K0XVR8
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1579979:WM2015 RS04640
gene id: 1579979:WM2015_RS04640
uniprot id: A0A0K0XUL1
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS02500
gene id: 1579979:WM2015_RS02500
uniprot id: A0A0K0XT94
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1579979:WM2015 RS00055
gene id: 1579979:WM2015_RS00055
uniprot id: A0A0K0XS06
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

1579979:WM2015 RS12285
gene id: 1579979:WM2015_RS12285
uniprot id: A0A0K0XYU0
names: Subcellular Location Annotation
messages: Cytoplasm

1579979:WM2015 RS07175
gene id: 1579979:WM2015_RS07175
uniprot id: A0A0K0XVZ8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1579979:WM2015 RS12160
gene id: 1579979:WM2015_RS12160
uniprot id: A0A0K0XYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS13235
gene id: 1579979:WM2015_RS13235
uniprot id: A0A0K0XZ57
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS01710
gene id: 1579979:WM2015_RS01710
uniprot id: A0A0K0XSP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS08185
gene id: 1579979:WM2015_RS08185
uniprot id: A0A0K0XWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1579979:WM2015 RS02250
gene id: 1579979:WM2015_RS02250
uniprot id: A0A0K0XT86
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1579979:WM2015 RS11560
gene id: 1579979:WM2015_RS11560
uniprot id: A0A0K0XYD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1579979:WM2015 RS07845
gene id: 1579979:WM2015_RS07845
uniprot id: A0A0K0XW62
names: Similarity
messages: Belongs to the RecJ family.

1579979:WM2015 RS05320
gene id: 1579979:WM2015_RS05320
uniprot id: A0A0K0XUU1
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1579979:WM2015 RS09565
gene id: 1579979:WM2015_RS09565
uniprot id: A0A0K0XX96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1579979:WM2015 RS00720
gene id: 1579979:WM2015_RS00720
uniprot id: A0A0K0XSA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1579979:WM2015 RS02565
gene id: 1579979:WM2015_RS02565
uniprot id: A0A0K0XT78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1579979:WM2015 RS01190
gene id: 1579979:WM2015_RS01190
uniprot id: A0A0K0XSD5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1579979:WM2015 RS08195
gene id: 1579979:WM2015_RS08195
uniprot id: A0A0K0XWA8
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS03335
gene id: 1579979:WM2015_RS03335
uniprot id: A0A0K0XTU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1579979:WM2015 RS14835
gene id: 1579979:WM2015_RS14835
uniprot id: A0A0K0Y083
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1579979:WM2015 RS15715
gene id: 1579979:WM2015_RS15715
uniprot id: A0A0K0XT92
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1579979:WM2015 RS12055
gene id: 1579979:WM2015_RS12055
uniprot id: A0A0K0XYI1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1579979:WM2015 RS02185
gene id: 1579979:WM2015_RS02185
uniprot id: A0A0K0XT04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1579979:WM2015 RS05225
gene id: 1579979:WM2015_RS05225
uniprot id: A0A0K0XUW7
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1579979:WM2015 RS07460
gene id: 1579979:WM2015_RS07460
uniprot id: A0A0K0XW39
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1579979:WM2015 RS07435
gene id: 1579979:WM2015_RS07435
uniprot id: A0A0K0XW34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS11160
gene id: 1579979:WM2015_RS11160
uniprot id: A0A0K0XY62
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1579979:WM2015 RS11210
gene id: 1579979:WM2015_RS11210
uniprot id: A0A0K0XY73
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1579979:WM2015 RS07145
gene id: 1579979:WM2015_RS07145
uniprot id: A0A0K0XVT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1579979:WM2015 RS08970
gene id: 1579979:WM2015_RS08970
uniprot id: A0A0K0XWT8
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1579979:WM2015 RS12300
gene id: 1579979:WM2015_RS12300
uniprot id: A0A0K0XYM4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1579979:WM2015 RS01165
gene id: 1579979:WM2015_RS01165
uniprot id: A0A0K0XSD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1579979:WM2015 RS07965
gene id: 1579979:WM2015_RS07965
uniprot id: A0A0K0XWD5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1579979:WM2015 RS06715
gene id: 1579979:WM2015_RS06715
uniprot id: A0A0K0XVI8
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS08115
gene id: 1579979:WM2015_RS08115
uniprot id: A0A0K0XWB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1579979:WM2015 RS09195
gene id: 1579979:WM2015_RS09195
uniprot id: A0A0K0XX03
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1579979:WM2015 RS06820
gene id: 1579979:WM2015_RS06820
uniprot id: A0A0K0XVN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1579979:WM2015 RS12080
gene id: 1579979:WM2015_RS12080
uniprot id: A0A0K0XYI5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1579979:WM2015 RS15075
gene id: 1579979:WM2015_RS15075
uniprot id: A0A0K0Y0A2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS15375
gene id: 1579979:WM2015_RS15375
uniprot id: A0A0K0Y0I4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS03040
gene id: 1579979:WM2015_RS03040
uniprot id: A0A0K0XTH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1579979:WM2015 RS13890
gene id: 1579979:WM2015_RS13890
uniprot id: A0A0K0XZP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1579979:WM2015 RS13425
gene id: 1579979:WM2015_RS13425
uniprot id: A0A0K0XZ96
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS10270
gene id: 1579979:WM2015_RS10270
uniprot id: A0A0K0XXG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1579979:WM2015 RS06370
gene id: 1579979:WM2015_RS06370
uniprot id: A0A0K0XVE5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1579979:WM2015 RS03850
gene id: 1579979:WM2015_RS03850
uniprot id: A0A0K0XU39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1579979:WM2015 RS11810
gene id: 1579979:WM2015_RS11810
uniprot id: A0A0K0XYD2
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1579979:WM2015 RS13705
gene id: 1579979:WM2015_RS13705
uniprot id: A0A0K0XZH3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1579979:WM2015 RS10925
gene id: 1579979:WM2015_RS10925
uniprot id: A0A0K0XXU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1579979:WM2015 RS13120
gene id: 1579979:WM2015_RS13120
uniprot id: A0A0K0XZ50
names: Subcellular Location Annotation
messages: Mitochondrion

1579979:WM2015 RS04910
gene id: 1579979:WM2015_RS04910
uniprot id: A0A0K0XUJ9
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS00675
gene id: 1579979:WM2015_RS00675
uniprot id: A0A0K0XS91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1579979:WM2015 RS11750
gene id: 1579979:WM2015_RS11750
uniprot id: A0A0K0XYH2
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1579979:WM2015 RS09805
gene id: 1579979:WM2015_RS09805
uniprot id: A0A0K0XXE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS01040
gene id: 1579979:WM2015_RS01040
uniprot id: A0A0K0XSA4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1579979:WM2015 RS12005
gene id: 1579979:WM2015_RS12005
uniprot id: A0A0K0XYN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1579979:WM2015 RS09590
gene id: 1579979:WM2015_RS09590
uniprot id: A0A0K0XXA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1579979:WM2015 RS02350
gene id: 1579979:WM2015_RS02350
uniprot id: A0A0K0XTA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1579979:WM2015 RS05255
gene id: 1579979:WM2015_RS05255
uniprot id: A0A0K0XUR4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1579979:WM2015 RS09820
gene id: 1579979:WM2015_RS09820
uniprot id: A0A0K0XX98
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1579979:WM2015 RS11575
gene id: 1579979:WM2015_RS11575
uniprot id: A0A0K0XYA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1579979:WM2015 RS03935
gene id: 1579979:WM2015_RS03935
uniprot id: A0A0K0XU06
names: Similarity
messages: Belongs to the GST superfamily.

1579979:WM2015 RS06045
gene id: 1579979:WM2015_RS06045
uniprot id: A0A0K0XVC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1579979:WM2015 RS03240
gene id: 1579979:WM2015_RS03240
uniprot id: A0A0K0XTS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1579979:WM2015 RS02035
gene id: 1579979:WM2015_RS02035
uniprot id: A0A0K0XSU5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1579979:WM2015 RS06350
gene id: 1579979:WM2015_RS06350
uniprot id: A0A0K0XVI3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1579979:WM2015 RS01755
gene id: 1579979:WM2015_RS01755
uniprot id: A0A0K0XSS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1579979:WM2015 RS09470
gene id: 1579979:WM2015_RS09470
uniprot id: A0A0K0XX21
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1579979:WM2015 RS07215
gene id: 1579979:WM2015_RS07215
uniprot id: A0A0K0XW03
names: Similarity
messages: Belongs to the arginine deiminase family.

1579979:WM2015 RS14000
gene id: 1579979:WM2015_RS14000
uniprot id: A0A0K0XZM0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1579979:WM2015 RS05565
gene id: 1579979:WM2015_RS05565
uniprot id: A0A0K0XV30
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1579979:WM2015 RS01280
gene id: 1579979:WM2015_RS01280
uniprot id: A0A0K0XSN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1579979:WM2015 RS11815
gene id: 1579979:WM2015_RS11815
uniprot id: A0A0K0XYC6
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1579979:WM2015 RS09300
gene id: 1579979:WM2015_RS09300
uniprot id: A0A0K0XWZ3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1579979:WM2015 RS06545
gene id: 1579979:WM2015_RS06545
uniprot id: A0A0K0XVH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1579979:WM2015 RS06640
gene id: 1579979:WM2015_RS06640
uniprot id: A0A0K0XVI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1579979:WM2015 RS07755
gene id: 1579979:WM2015_RS07755
uniprot id: A0A0K0XW50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1579979:WM2015 RS07285
gene id: 1579979:WM2015_RS07285
uniprot id: A0A0K0XVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1579979:WM2015 RS08510
gene id: 1579979:WM2015_RS08510
uniprot id: A0A0K0XWN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1579979:WM2015 RS12270
gene id: 1579979:WM2015_RS12270
uniprot id: A0A0K0XYM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS01370
gene id: 1579979:WM2015_RS01370
uniprot id: A0A0K0XSJ6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

1579979:WM2015 RS05040
gene id: 1579979:WM2015_RS05040
uniprot id: A0A0K0XUN8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1579979:WM2015 RS09600
gene id: 1579979:WM2015_RS09600
uniprot id: A0A0K0XX40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1579979:WM2015 RS10575
gene id: 1579979:WM2015_RS10575
uniprot id: A0A0K0XXQ1
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1579979:WM2015 RS06980
gene id: 1579979:WM2015_RS06980
uniprot id: A0A0K0XVP5
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS03080
gene id: 1579979:WM2015_RS03080
uniprot id: A0A0K0XTP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1579979:WM2015 RS02340
gene id: 1579979:WM2015_RS02340
uniprot id: A0A0K0XT07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1579979:WM2015 RS04480
gene id: 1579979:WM2015_RS04480
uniprot id: A0A0K0XU89
names: Similarity
messages: Belongs to the Gfa family.

1579979:WM2015 RS04600
gene id: 1579979:WM2015_RS04600
uniprot id: A0A0K0XUD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1579979:WM2015 RS10220
gene id: 1579979:WM2015_RS10220
uniprot id: A0A0K0XXI2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1579979:WM2015 RS01245
gene id: 1579979:WM2015_RS01245
uniprot id: A0A0K0XSJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

1579979:WM2015 RS03030
gene id: 1579979:WM2015_RS03030
uniprot id: A0A0K0XTK2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1579979:WM2015 RS14520
gene id: 1579979:WM2015_RS14520
uniprot id: A0A0K0XZX7
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS01805
gene id: 1579979:WM2015_RS01805
uniprot id: A0A0K0XST7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1579979:WM2015 RS10225
gene id: 1579979:WM2015_RS10225
uniprot id: A0A0K0XXP9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1579979:WM2015 RS08975
gene id: 1579979:WM2015_RS08975
uniprot id: A0A0K0XWY6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1579979:WM2015 RS06985
gene id: 1579979:WM2015_RS06985
uniprot id: A0A0K0XVN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1579979:WM2015 RS04740
gene id: 1579979:WM2015_RS04740
uniprot id: A0A0K0XUN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1579979:WM2015 RS08110
gene id: 1579979:WM2015_RS08110
uniprot id: A0A0K0XWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1579979:WM2015 RS06745
gene id: 1579979:WM2015_RS06745
uniprot id: A0A0K0XVM1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1579979:WM2015 RS05870
gene id: 1579979:WM2015_RS05870
uniprot id: A0A0K0XV93
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS02875
gene id: 1579979:WM2015_RS02875
uniprot id: A0A0K0XTH1
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS12315
gene id: 1579979:WM2015_RS12315
uniprot id: A0A0K0XYU4
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1579979:WM2015 RS10755
gene id: 1579979:WM2015_RS10755
uniprot id: A0A0K0XY05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1579979:WM2015 RS12615
gene id: 1579979:WM2015_RS12615
uniprot id: A0A0K0XYZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS08090
gene id: 1579979:WM2015_RS08090
uniprot id: A0A0K0XWB4
names: Similarity
messages: Belongs to the peptidase S41A family.

1579979:WM2015 RS09040
gene id: 1579979:WM2015_RS09040
uniprot id: A0A0K0XWU2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1579979:WM2015 RS06505
gene id: 1579979:WM2015_RS06505
uniprot id: A0A0K0XVK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1579979:WM2015 RS06170
gene id: 1579979:WM2015_RS06170
uniprot id: A0A0K0XV66
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1579979:WM2015 RS00735
gene id: 1579979:WM2015_RS00735
uniprot id: A0A0K0XS74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1579979:WM2015 RS09750
gene id: 1579979:WM2015_RS09750
uniprot id: A0A0K0XX82
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS01320
gene id: 1579979:WM2015_RS01320
uniprot id: A0A0K0XSI7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1579979:WM2015 RS00740
gene id: 1579979:WM2015_RS00740
uniprot id: A0A0K0XS52
names: Similarity
messages: Belongs to the peptidase S8 family.

1579979:WM2015 RS04575
gene id: 1579979:WM2015_RS04575
uniprot id: A0A0K0XUD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1579979:WM2015 RS04735
gene id: 1579979:WM2015_RS04735
uniprot id: A0A0K0XUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1579979:WM2015 RS00500
gene id: 1579979:WM2015_RS00500
uniprot id: A0A0K0XS93
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1579979:WM2015 RS07920
gene id: 1579979:WM2015_RS07920
uniprot id: A0A0K0XW79
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1579979:WM2015 RS03050
gene id: 1579979:WM2015_RS03050
uniprot id: A0A0K0XTK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1579979:WM2015 RS02530
gene id: 1579979:WM2015_RS02530
uniprot id: A0A0K0XTE0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1579979:WM2015 RS01590
gene id: 1579979:WM2015_RS01590
uniprot id: A0A0K0XSV7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1579979:WM2015 RS01645
gene id: 1579979:WM2015_RS01645
uniprot id: A0A0K0XSW5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1579979:WM2015 RS08710
gene id: 1579979:WM2015_RS08710
uniprot id: A0A0K0XWU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1579979:WM2015 RS03070
gene id: 1579979:WM2015_RS03070
uniprot id: A0A0K0XTF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1579979:WM2015 RS06455
gene id: 1579979:WM2015_RS06455
uniprot id: A0A0K0XVE7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1579979:WM2015 RS02760
gene id: 1579979:WM2015_RS02760
uniprot id: A0A0K0XTI3
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1579979:WM2015 RS14620
gene id: 1579979:WM2015_RS14620
uniprot id: A0A0K0Y014
names: Similarity
messages: Belongs to the UPF0234 family.

1579979:WM2015 RS07970
gene id: 1579979:WM2015_RS07970
uniprot id: A0A0K0XW89
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1579979:WM2015 RS14730
gene id: 1579979:WM2015_RS14730
uniprot id: A0A0K0Y062
names: Similarity
messages: Belongs to the pirin family.

1579979:WM2015 RS05095
gene id: 1579979:WM2015_RS05095
uniprot id: A0A0K0XUU5
names: Similarity
messages: Belongs to the peptidase S9C family.

1579979:WM2015 RS12425
gene id: 1579979:WM2015_RS12425
uniprot id: A0A0K0XYW3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1579979:WM2015 RS10350
gene id: 1579979:WM2015_RS10350
uniprot id: A0A0K0XXK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1579979:WM2015 RS08335
gene id: 1579979:WM2015_RS08335
uniprot id: A0A0K0XWG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1579979:WM2015 RS14880
gene id: 1579979:WM2015_RS14880
uniprot id: A0A0K0Y064
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS09155
gene id: 1579979:WM2015_RS09155
uniprot id: A0A0K0XWX2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1579979:WM2015 RS11240
gene id: 1579979:WM2015_RS11240
uniprot id: A0A0K0XY25
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1579979:WM2015 RS00730
gene id: 1579979:WM2015_RS00730
uniprot id: A0A0K0XSD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1579979:WM2015 RS09745
gene id: 1579979:WM2015_RS09745
uniprot id: A0A0K0XX65
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1579979:WM2015 RS13655
gene id: 1579979:WM2015_RS13655
uniprot id: A0A0K0XZG4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1579979:WM2015 RS15225
gene id: 1579979:WM2015_RS15225
uniprot id: A0A0K0Y0B1
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS07990
gene id: 1579979:WM2015_RS07990
uniprot id: A0A0K0XWE0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1579979:WM2015 RS11990
gene id: 1579979:WM2015_RS11990
uniprot id: A0A0K0XYG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1579979:WM2015 RS00490
gene id: 1579979:WM2015_RS00490
uniprot id: A0A0K0XS58
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS05580
gene id: 1579979:WM2015_RS05580
uniprot id: A0A0K0XUZ2
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1579979:WM2015 RS07800
gene id: 1579979:WM2015_RS07800
uniprot id: A0A0K0XW27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1579979:WM2015 RS12340
gene id: 1579979:WM2015_RS12340
uniprot id: A0A0K0XYU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1579979:WM2015 RS09250
gene id: 1579979:WM2015_RS09250
uniprot id: A0A0K0XWW2
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1579979:WM2015 RS07255
gene id: 1579979:WM2015_RS07255
uniprot id: A0A0K0XVS2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1579979:WM2015 RS07880
gene id: 1579979:WM2015_RS07880
uniprot id: A0A0K0XW75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1579979:WM2015 RS07520
gene id: 1579979:WM2015_RS07520
uniprot id: A0A0K0XVZ6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1579979:WM2015 RS11655
gene id: 1579979:WM2015_RS11655
uniprot id: A0A0K0XYF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1579979:WM2015 RS10185
gene id: 1579979:WM2015_RS10185
uniprot id: A0A0K0XXG6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1579979:WM2015 RS00970
gene id: 1579979:WM2015_RS00970
uniprot id: A0A0K0XSE4
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS02610
gene id: 1579979:WM2015_RS02610
uniprot id: A0A0K0XTF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1579979:WM2015 RS04840
gene id: 1579979:WM2015_RS04840
uniprot id: A0A0K0XUQ2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1579979:WM2015 RS10620
gene id: 1579979:WM2015_RS10620
uniprot id: A0A0K0XXN8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1579979:WM2015 RS11500
gene id: 1579979:WM2015_RS11500
uniprot id: A0A0K0XY90
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1579979:WM2015 RS06575
gene id: 1579979:WM2015_RS06575
uniprot id: A0A0K0XVL4
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

1579979:WM2015 RS06660
gene id: 1579979:WM2015_RS06660
uniprot id: A0A0K0XVF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1579979:WM2015 RS00905
gene id: 1579979:WM2015_RS00905
uniprot id: A0A0K0XSH4
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS07250
gene id: 1579979:WM2015_RS07250
uniprot id: A0A0K0XVU3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1579979:WM2015 RS11725
gene id: 1579979:WM2015_RS11725
uniprot id: A0A0K0XYG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1579979:WM2015 RS07110
gene id: 1579979:WM2015_RS07110
uniprot id: A0A0K0XVR5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1579979:WM2015 RS02015
gene id: 1579979:WM2015_RS02015
uniprot id: A0A0K0XT00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1579979:WM2015 RS11610
gene id: 1579979:WM2015_RS11610
uniprot id: A0A0K0XYE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1579979:WM2015 RS07260
gene id: 1579979:WM2015_RS07260
uniprot id: A0A0K0XVV6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1579979:WM2015 RS08285
gene id: 1579979:WM2015_RS08285
uniprot id: A0A0K0XWL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1579979:WM2015 RS02965
gene id: 1579979:WM2015_RS02965
uniprot id: A0A0K0XTF9
names: Similarity
messages: Belongs to the peptidase U62 family.

1579979:WM2015 RS09205
gene id: 1579979:WM2015_RS09205
uniprot id: A0A0K0XWV1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1579979:WM2015 RS02175
gene id: 1579979:WM2015_RS02175
uniprot id: A0A0K0XT70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1579979:WM2015 RS04630
gene id: 1579979:WM2015_RS04630
uniprot id: A0A0K0XUB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1579979:WM2015 RS11440
gene id: 1579979:WM2015_RS11440
uniprot id: A0A0K0XY63
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS00935
gene id: 1579979:WM2015_RS00935
uniprot id: A0A0K0XSB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1579979:WM2015 RS02130
gene id: 1579979:WM2015_RS02130
uniprot id: A0A0K0XT58
names: Similarity
messages: Belongs to the acylphosphatase family.

1579979:WM2015 RS01800
gene id: 1579979:WM2015_RS01800
uniprot id: A0A0K0XSZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1579979:WM2015 RS08875
gene id: 1579979:WM2015_RS08875
uniprot id: A0A0K0XWX0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1579979:WM2015 RS05670
gene id: 1579979:WM2015_RS05670
uniprot id: A0A0K0XUZ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1579979:WM2015 RS13250
gene id: 1579979:WM2015_RS13250
uniprot id: A0A0K0XZC7
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1579979:WM2015 RS06785
gene id: 1579979:WM2015_RS06785
uniprot id: A0A0K0XVL9
names: Similarity
messages: Belongs to the TPP enzyme family.

1579979:WM2015 RS05570
gene id: 1579979:WM2015_RS05570
uniprot id: A0A0K0XUX4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

1579979:WM2015 RS00030
gene id: 1579979:WM2015_RS00030
uniprot id: A0A0K0XS01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1579979:WM2015 RS02945
gene id: 1579979:WM2015_RS02945
uniprot id: A0A0K0XTC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1579979:WM2015 RS11465
gene id: 1579979:WM2015_RS11465
uniprot id: A0A0K0XY67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1579979:WM2015 RS01720
gene id: 1579979:WM2015_RS01720
uniprot id: A0A0K0XSY1
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1579979:WM2015 RS01410
gene id: 1579979:WM2015_RS01410
uniprot id: A0A0K0XSQ5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1579979:WM2015 RS00480
gene id: 1579979:WM2015_RS00480
uniprot id: A0A0K0XS20
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1579979:WM2015 RS09265
gene id: 1579979:WM2015_RS09265
uniprot id: A0A0K0XX20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1579979:WM2015 RS08470
gene id: 1579979:WM2015_RS08470
uniprot id: A0A0K0XWP7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS01035
gene id: 1579979:WM2015_RS01035
uniprot id: A0A0K0XSD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1579979:WM2015 RS11565
gene id: 1579979:WM2015_RS11565
uniprot id: A0A0K0XY88
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1579979:WM2015 RS07340
gene id: 1579979:WM2015_RS07340
uniprot id: A0A0K0XW28
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS07070
gene id: 1579979:WM2015_RS07070
uniprot id: A0A0K0XVX8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1579979:WM2015 RS06390
gene id: 1579979:WM2015_RS06390
uniprot id: A0A0K0XVI5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1579979:WM2015 RS06870
gene id: 1579979:WM2015_RS06870
uniprot id: A0A0K0XVP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1579979:WM2015 RS00160
gene id: 1579979:WM2015_RS00160
uniprot id: A0A0K0XRV2
names: Similarity
messages: Belongs to the P(II) protein family.

1579979:WM2015 RS13225
gene id: 1579979:WM2015_RS13225
uniprot id: A0A0K0XZC4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1579979:WM2015 RS08355
gene id: 1579979:WM2015_RS08355
uniprot id: A0A0K0XWD9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1579979:WM2015 RS01955
gene id: 1579979:WM2015_RS01955
uniprot id: A0A0K0XSW0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1579979:WM2015 RS11980
gene id: 1579979:WM2015_RS11980
uniprot id: A0A0K0XYM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1579979:WM2015 RS06280
gene id: 1579979:WM2015_RS06280
uniprot id: A0A0K0XVH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1579979:WM2015 RS11605
gene id: 1579979:WM2015_RS11605
uniprot id: A0A0K0XYE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1579979:WM2015 RS16005
gene id: 1579979:WM2015_RS16005
uniprot id: A0A0K0XSK5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS05190
gene id: 1579979:WM2015_RS05190
uniprot id: A0A0K0XUR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1579979:WM2015 RS07685
gene id: 1579979:WM2015_RS07685
uniprot id: A0A0K0XW35
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1579979:WM2015 RS16050
gene id: 1579979:WM2015_RS16050
uniprot id: A0A0K0XXF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1579979:WM2015 RS02850
gene id: 1579979:WM2015_RS02850
uniprot id: A0A0K0XTG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1579979:WM2015 RS14210
gene id: 1579979:WM2015_RS14210
uniprot id: A0A0K0XZR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1579979:WM2015 RS12470
gene id: 1579979:WM2015_RS12470
uniprot id: A0A0K0XYX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1579979:WM2015 RS05710
gene id: 1579979:WM2015_RS05710
uniprot id: A0A0K0XV64
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1579979:WM2015 RS11555
gene id: 1579979:WM2015_RS11555
uniprot id: A0A0K0XYD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1579979:WM2015 RS07270
gene id: 1579979:WM2015_RS07270
uniprot id: A0A0K0XW04
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS04225
gene id: 1579979:WM2015_RS04225
uniprot id: A0A0K0XU72
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS09505
gene id: 1579979:WM2015_RS09505
uniprot id: A0A0K0XXA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1579979:WM2015 RS13740
gene id: 1579979:WM2015_RS13740
uniprot id: A0A0K0XZL1
names: Similarity
messages: Belongs to the P(II) protein family.

1579979:WM2015 RS11130
gene id: 1579979:WM2015_RS11130
uniprot id: A0A0K0XY59
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1579979:WM2015 RS09835
gene id: 1579979:WM2015_RS09835
uniprot id: A0A0K0XX97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1579979:WM2015 RS11715
gene id: 1579979:WM2015_RS11715
uniprot id: A0A0K0XYA5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1579979:WM2015 RS06475
gene id: 1579979:WM2015_RS06475
uniprot id: A0A0K0XVJ8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1579979:WM2015 RS02570
gene id: 1579979:WM2015_RS02570
uniprot id: A0A0K0XT54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1579979:WM2015 RS01640
gene id: 1579979:WM2015_RS01640
uniprot id: A0A0K0XST5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1579979:WM2015 RS16035
gene id: 1579979:WM2015_RS16035
uniprot id: A0A0K0XX69
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1579979:WM2015 RS10705
gene id: 1579979:WM2015_RS10705
uniprot id: A0A0K0XXZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1579979:WM2015 RS06855
gene id: 1579979:WM2015_RS06855
uniprot id: A0A0K0XVT4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1579979:WM2015 RS00615
gene id: 1579979:WM2015_RS00615
uniprot id: A0A0K0XS80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1579979:WM2015 RS00100
gene id: 1579979:WM2015_RS00100
uniprot id: A0A0K0XS11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1579979:WM2015 RS07870
gene id: 1579979:WM2015_RS07870
uniprot id: A0A0K0XW69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS02780
gene id: 1579979:WM2015_RS02780
uniprot id: A0A0K0XTI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1579979:WM2015 RS14245
gene id: 1579979:WM2015_RS14245
uniprot id: A0A0K0XZT2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1579979:WM2015 RS04565
gene id: 1579979:WM2015_RS04565
uniprot id: A0A0K0XUJ6
names: Similarity
messages: Belongs to the PhoH family.

1579979:WM2015 RS05490
gene id: 1579979:WM2015_RS05490
uniprot id: A0A0K0XUV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1579979:WM2015 RS01285
gene id: 1579979:WM2015_RS01285
uniprot id: A0A0K0XSN6
names: Similarity
messages: Belongs to the YicC/YloC family.

1579979:WM2015 RS00110
gene id: 1579979:WM2015_RS00110
uniprot id: A0A0K0XRU2
names: Similarity
messages: Belongs to the peptidase S9C family.

1579979:WM2015 RS14050
gene id: 1579979:WM2015_RS14050
uniprot id: A0A0K0XZM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1579979:WM2015 RS06175
gene id: 1579979:WM2015_RS06175
uniprot id: A0A0K0XVB0
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1579979:WM2015 RS04485
gene id: 1579979:WM2015_RS04485
uniprot id: A0A0K0XUD5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1579979:WM2015 RS06605
gene id: 1579979:WM2015_RS06605
uniprot id: A0A0K0XVH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1579979:WM2015 RS06425
gene id: 1579979:WM2015_RS06425
uniprot id: A0A0K0XVJ0
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1579979:WM2015 RS10500
gene id: 1579979:WM2015_RS10500
uniprot id: A0A0K0XXN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1579979:WM2015 RS01890
gene id: 1579979:WM2015_RS01890
uniprot id: A0A0K0XSX3
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS02575
gene id: 1579979:WM2015_RS02575
uniprot id: A0A0K0XTB0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1579979:WM2015 RS02150
gene id: 1579979:WM2015_RS02150
uniprot id: A0A0K0XT66
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1579979:WM2015 RS11305
gene id: 1579979:WM2015_RS11305
uniprot id: A0A0K0XY96
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1579979:WM2015 RS01415
gene id: 1579979:WM2015_RS01415
uniprot id: A0A0K0XSQ6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1579979:WM2015 RS03435
gene id: 1579979:WM2015_RS03435
uniprot id: A0A0K0XTM5
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1579979:WM2015 RS08370
gene id: 1579979:WM2015_RS08370
uniprot id: A0A0K0XWL4
names: Similarity
messages: Belongs to the BolA/IbaG family.

1579979:WM2015 RS10680
gene id: 1579979:WM2015_RS10680
uniprot id: A0A0K0XXY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1579979:WM2015 RS11315
gene id: 1579979:WM2015_RS11315
uniprot id: A0A0K0XY37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1579979:WM2015 RS02145
gene id: 1579979:WM2015_RS02145
uniprot id: A0A0K0XT25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1579979:WM2015 RS11175
gene id: 1579979:WM2015_RS11175
uniprot id: A0A0K0XY19
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1579979:WM2015 RS13275
gene id: 1579979:WM2015_RS13275
uniprot id: A0A0K0XZD3
names: Similarity
messages: Belongs to the pyruvate kinase family.

1579979:WM2015 RS06520
gene id: 1579979:WM2015_RS06520
uniprot id: A0A0K0XVG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1579979:WM2015 RS07635
gene id: 1579979:WM2015_RS07635
uniprot id: A0A0K0XW81
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1579979:WM2015 RS08045
gene id: 1579979:WM2015_RS08045
uniprot id: A0A0K0XW77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1579979:WM2015 RS03970
gene id: 1579979:WM2015_RS03970
uniprot id: A0A0K0XU25
names: Similarity
messages: Belongs to the CcdB toxin family.

1579979:WM2015 RS11395
gene id: 1579979:WM2015_RS11395
uniprot id: A0A0K0XY40
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1579979:WM2015 RS01905
gene id: 1579979:WM2015_RS01905
uniprot id: A0A0K0XSV0
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS07415
gene id: 1579979:WM2015_RS07415
uniprot id: A0A0K0XVX4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Homodimer.

1579979:WM2015 RS14735
gene id: 1579979:WM2015_RS14735
uniprot id: A0A0K0Y007
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1579979:WM2015 RS01575
gene id: 1579979:WM2015_RS01575
uniprot id: A0A0K0XSN1
names: Similarity
messages: Belongs to the DprA/Smf family.

1579979:WM2015 RS08375
gene id: 1579979:WM2015_RS08375
uniprot id: A0A0K0XWG4
names: Similarity
messages: Belongs to the YciI family.

1579979:WM2015 RS09770
gene id: 1579979:WM2015_RS09770
uniprot id: A0A0K0XX70
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1579979:WM2015 RS00125
gene id: 1579979:WM2015_RS00125
uniprot id: A0A0K0XS16
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1579979:WM2015 RS12180
gene id: 1579979:WM2015_RS12180
uniprot id: A0A0K0XYJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1579979:WM2015 RS02115
gene id: 1579979:WM2015_RS02115
uniprot id: A0A0K0XSW1
names: Similarity
messages: Belongs to the ArsC family.

1579979:WM2015 RS07915
gene id: 1579979:WM2015_RS07915
uniprot id: A0A0K0XWC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1579979:WM2015 RS12495
gene id: 1579979:WM2015_RS12495
uniprot id: A0A0K0XYS9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1579979:WM2015 RS02935
gene id: 1579979:WM2015_RS02935
uniprot id: A0A0K0XTL7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1579979:WM2015 RS10580
gene id: 1579979:WM2015_RS10580
uniprot id: A0A0K0XXX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1579979:WM2015 RS02915
gene id: 1579979:WM2015_RS02915
uniprot id: A0A0K0XTF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1579979:WM2015 RS13320
gene id: 1579979:WM2015_RS13320
uniprot id: A0A0K0XZE3
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

1579979:WM2015 RS01730
gene id: 1579979:WM2015_RS01730
uniprot id: A0A0K0XSS6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS10345
gene id: 1579979:WM2015_RS10345
uniprot id: A0A0K0XXI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1579979:WM2015 RS11515
gene id: 1579979:WM2015_RS11515
uniprot id: A0A0K0XY79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1579979:WM2015 RS07850
gene id: 1579979:WM2015_RS07850
uniprot id: A0A0K0XW37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1579979:WM2015 RS02065
gene id: 1579979:WM2015_RS02065
uniprot id: A0A0K0XT10
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1579979:WM2015 RS09390
gene id: 1579979:WM2015_RS09390
uniprot id: A0A0K0XX62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1579979:WM2015 RS04210
gene id: 1579979:WM2015_RS04210
uniprot id: A0A0K0XU87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1579979:WM2015 RS07830
gene id: 1579979:WM2015_RS07830
uniprot id: A0A0K0XW65
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS13985
gene id: 1579979:WM2015_RS13985
uniprot id: A0A0K0XZS8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1579979:WM2015 RS07890
gene id: 1579979:WM2015_RS07890
uniprot id: A0A0K0XWC0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1579979:WM2015 RS02580
gene id: 1579979:WM2015_RS02580
uniprot id: A0A0K0XTE8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1579979:WM2015 RS02025
gene id: 1579979:WM2015_RS02025
uniprot id: A0A0K0XT37
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1579979:WM2015 RS13700
gene id: 1579979:WM2015_RS13700
uniprot id: A0A0K0XZF7
names: Similarity
messages: Belongs to the GSP E family.

1579979:WM2015 RS09855
gene id: 1579979:WM2015_RS09855
uniprot id: A0A0K0XXF5
names: Similarity
messages: Belongs to the MlaA family.

1579979:WM2015 RS07465
gene id: 1579979:WM2015_RS07465
uniprot id: A0A0K0XVY5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1579979:WM2015 RS01705
gene id: 1579979:WM2015_RS01705
uniprot id: A0A0K0XSS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1579979:WM2015 RS03250
gene id: 1579979:WM2015_RS03250
uniprot id: A0A0K0XTJ0
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS12715
gene id: 1579979:WM2015_RS12715
uniprot id: A0A0K0XZ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1579979:WM2015 RS15030
gene id: 1579979:WM2015_RS15030
uniprot id: A0A0K0Y092
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS10830
gene id: 1579979:WM2015_RS10830
uniprot id: A0A0K0XY18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS09070
gene id: 1579979:WM2015_RS09070
uniprot id: A0A0K0XWU8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1579979:WM2015 RS07425
gene id: 1579979:WM2015_RS07425
uniprot id: A0A0K0XVY7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1579979:WM2015 RS10535
gene id: 1579979:WM2015_RS10535
uniprot id: A0A0K0XXT9
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1579979:WM2015 RS01665
gene id: 1579979:WM2015_RS01665
uniprot id: A0A0K0XST8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1579979:WM2015 RS10985
gene id: 1579979:WM2015_RS10985
uniprot id: A0A0K0XXY2
names: Similarity
messages: Belongs to the YciI family.

1579979:WM2015 RS02665
gene id: 1579979:WM2015_RS02665
uniprot id: A0A0K0XT98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1579979:WM2015 RS06360
gene id: 1579979:WM2015_RS06360
uniprot id: A0A0K0XVD2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1579979:WM2015 RS01790
gene id: 1579979:WM2015_RS01790
uniprot id: A0A0K0XSV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1579979:WM2015 RS00770
gene id: 1579979:WM2015_RS00770
uniprot id: A0A0K0XSB0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1579979:WM2015 RS09240
gene id: 1579979:WM2015_RS09240
uniprot id: A0A0K0XX14
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1579979:WM2015 RS09450
gene id: 1579979:WM2015_RS09450
uniprot id: A0A0K0XX34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1579979:WM2015 RS00695
gene id: 1579979:WM2015_RS00695
uniprot id: A0A0K0XS95
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS08805
gene id: 1579979:WM2015_RS08805
uniprot id: A0A0K0XWM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS02435
gene id: 1579979:WM2015_RS02435
uniprot id: A0A0K0XTB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS01375
gene id: 1579979:WM2015_RS01375
uniprot id: A0A0K0XSH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1579979:WM2015 RS12000
gene id: 1579979:WM2015_RS12000
uniprot id: A0A0K0XYN2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS01565
gene id: 1579979:WM2015_RS01565
uniprot id: A0A0K0XSV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1579979:WM2015 RS08595
gene id: 1579979:WM2015_RS08595
uniprot id: A0A0K0XWI4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1579979:WM2015 RS02855
gene id: 1579979:WM2015_RS02855
uniprot id: A0A0K0XTK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1579979:WM2015 RS09955
gene id: 1579979:WM2015_RS09955
uniprot id: A0A0K0XXH3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1579979:WM2015 RS06730
gene id: 1579979:WM2015_RS06730
uniprot id: A0A0K0XVQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1579979:WM2015 RS13445
gene id: 1579979:WM2015_RS13445
uniprot id: A0A0K0XZF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1579979:WM2015 RS05545
gene id: 1579979:WM2015_RS05545
uniprot id: A0A0K0XUW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1579979:WM2015 RS03410
gene id: 1579979:WM2015_RS03410
uniprot id: A0A0K0XTM0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS15105
gene id: 1579979:WM2015_RS15105
uniprot id: A0A0K0Y0G0
names: Similarity
messages: Belongs to the creatininase superfamily.

1579979:WM2015 RS10975
gene id: 1579979:WM2015_RS10975
uniprot id: A0A0K0XXX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1579979:WM2015 RS00155
gene id: 1579979:WM2015_RS00155
uniprot id: A0A0K0XS24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1579979:WM2015 RS04745
gene id: 1579979:WM2015_RS04745
uniprot id: A0A0K0XUM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1579979:WM2015 RS06905
gene id: 1579979:WM2015_RS06905
uniprot id: A0A0K0XVP4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1579979:WM2015 RS10395
gene id: 1579979:WM2015_RS10395
uniprot id: A0A0K0XXJ4
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS12655
gene id: 1579979:WM2015_RS12655
uniprot id: A0A0K0XYW2
names: Similarity
messages: Belongs to the peptidase M17 family.

1579979:WM2015 RS05950
gene id: 1579979:WM2015_RS05950
uniprot id: A0A0K0XV50
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

1579979:WM2015 RS06940
gene id: 1579979:WM2015_RS06940
uniprot id: A0A0K0XVP7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1579979:WM2015 RS09230
gene id: 1579979:WM2015_RS09230
uniprot id: A0A0K0XWY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1579979:WM2015 RS02635
gene id: 1579979:WM2015_RS02635
uniprot id: A0A0K0XTF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1579979:WM2015 RS12725
gene id: 1579979:WM2015_RS12725
uniprot id: A0A0K0XYV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1579979:WM2015 RS15090
gene id: 1579979:WM2015_RS15090
uniprot id: A0A0K0Y077
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1579979:WM2015 RS02630
gene id: 1579979:WM2015_RS02630
uniprot id: A0A0K0XTF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1579979:WM2015 RS11125
gene id: 1579979:WM2015_RS11125
uniprot id: A0A0K0XY06
names: Similarity
messages: Belongs to the UPF0178 family.

1579979:WM2015 RS03265
gene id: 1579979:WM2015_RS03265
uniprot id: A0A0K0XTT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1579979:WM2015 RS02245
gene id: 1579979:WM2015_RS02245
uniprot id: A0A0K0XT45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS05560
gene id: 1579979:WM2015_RS05560
uniprot id: A0A0K0XV35
names: Similarity
messages: Belongs to the SufE family.

1579979:WM2015 RS07770
gene id: 1579979:WM2015_RS07770
uniprot id: A0A0K0XW46
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1579979:WM2015 RS04850
gene id: 1579979:WM2015_RS04850
uniprot id: A0A0K0XUI7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1579979:WM2015 RS09320
gene id: 1579979:WM2015_RS09320
uniprot id: A0A0K0XX04
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS01545
gene id: 1579979:WM2015_RS01545
uniprot id: A0A0K0XSK7
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS07185
gene id: 1579979:WM2015_RS07185
uniprot id: A0A0K0XVT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1579979:WM2015 RS13060
gene id: 1579979:WM2015_RS13060
uniprot id: A0A0K0XZ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1579979:WM2015 RS11525
gene id: 1579979:WM2015_RS11525
uniprot id: A0A0K0XY92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1579979:WM2015 RS04595
gene id: 1579979:WM2015_RS04595
uniprot id: A0A0K0XUJ7
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1579979:WM2015 RS07910
gene id: 1579979:WM2015_RS07910
uniprot id: A0A0K0XWD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1579979:WM2015 RS07055
gene id: 1579979:WM2015_RS07055
uniprot id: A0A0K0XVQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1579979:WM2015 RS03425
gene id: 1579979:WM2015_RS03425
uniprot id: A0A0K0XTW2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1579979:WM2015 RS11245
gene id: 1579979:WM2015_RS11245
uniprot id: A0A0K0XY08
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1579979:WM2015 RS01740
gene id: 1579979:WM2015_RS01740
uniprot id: A0A0K0XSU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1579979:WM2015 RS02730
gene id: 1579979:WM2015_RS02730
uniprot id: A0A0K0XTH6
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS12975
gene id: 1579979:WM2015_RS12975
uniprot id: A0A0K0XZ09
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1579979:WM2015 RS07695
gene id: 1579979:WM2015_RS07695
uniprot id: A0A0K0XW31
names: Similarity
messages: Belongs to the peptidase S8 family.

1579979:WM2015 RS03290
gene id: 1579979:WM2015_RS03290
uniprot id: A0A0K0XTT8
names: Similarity
messages: Belongs to the TrpC family.

1579979:WM2015 RS06810
gene id: 1579979:WM2015_RS06810
uniprot id: A0A0K0XVM2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1579979:WM2015 RS01420
gene id: 1579979:WM2015_RS01420
uniprot id: A0A0K0XSK6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1579979:WM2015 RS08840
gene id: 1579979:WM2015_RS08840
uniprot id: A0A0K0XWR3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1579979:WM2015 RS01460
gene id: 1579979:WM2015_RS01460
uniprot id: A0A0K0XSR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS10100
gene id: 1579979:WM2015_RS10100
uniprot id: A0A0K0XXM4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1579979:WM2015 RS06220
gene id: 1579979:WM2015_RS06220
uniprot id: A0A0K0XV76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1579979:WM2015 RS07300
gene id: 1579979:WM2015_RS07300
uniprot id: A0A0K0XVV3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1579979:WM2015 RS09650
gene id: 1579979:WM2015_RS09650
uniprot id: A0A0K0XX63
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1579979:WM2015 RS10460
gene id: 1579979:WM2015_RS10460
uniprot id: A0A0K0XXS1
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS00670
gene id: 1579979:WM2015_RS00670
uniprot id: A0A0K0XS37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1579979:WM2015 RS08040
gene id: 1579979:WM2015_RS08040
uniprot id: A0A0K0XWA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1579979:WM2015 RS00920
gene id: 1579979:WM2015_RS00920
uniprot id: A0A0K0XSE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetylcitrulline deacetylase subfamily.
messages: Binds 1 Co(2+) ion per subunit.
messages: Catalyzes the deacetylation of N-acetyl-L-citrulline to produce L-citrulline. This is a step in an alternative arginine biosynthesis pathway.

1579979:WM2015 RS01875
gene id: 1579979:WM2015_RS01875
uniprot id: A0A0K0XT08
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1579979:WM2015 RS02345
gene id: 1579979:WM2015_RS02345
uniprot id: A0A0K0XT65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1579979:WM2015 RS11970
gene id: 1579979:WM2015_RS11970
uniprot id: A0A0K0XYI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1579979:WM2015 RS03210
gene id: 1579979:WM2015_RS03210
uniprot id: A0A0K0XTS2
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1579979:WM2015 RS10105
gene id: 1579979:WM2015_RS10105
uniprot id: A0A0K0XXK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1579979:WM2015 RS00785
gene id: 1579979:WM2015_RS00785
uniprot id: A0A0K0XS86
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1579979:WM2015 RS11955
gene id: 1579979:WM2015_RS11955
uniprot id: A0A0K0XYG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1579979:WM2015 RS02155
gene id: 1579979:WM2015_RS02155
uniprot id: A0A0K0XT62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1579979:WM2015 RS13370
gene id: 1579979:WM2015_RS13370
uniprot id: A0A0K0XZE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1579979:WM2015 RS01490
gene id: 1579979:WM2015_RS01490
uniprot id: A0A0K0XSL7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS09305
gene id: 1579979:WM2015_RS09305
uniprot id: A0A0K0XX10
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1579979:WM2015 RS02110
gene id: 1579979:WM2015_RS02110
uniprot id: A0A0K0XSZ0
names: Similarity
messages: Belongs to the WrbA family.

1579979:WM2015 RS11495
gene id: 1579979:WM2015_RS11495
uniprot id: A0A0K0XY61
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1579979:WM2015 RS15020
gene id: 1579979:WM2015_RS15020
uniprot id: A0A0K0Y063
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS12460
gene id: 1579979:WM2015_RS12460
uniprot id: A0A0K0XYQ4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1579979:WM2015 RS10480
gene id: 1579979:WM2015_RS10480
uniprot id: A0A0K0XXV0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1579979:WM2015 RS02785
gene id: 1579979:WM2015_RS02785
uniprot id: A0A0K0XTI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1579979:WM2015 RS09575
gene id: 1579979:WM2015_RS09575
uniprot id: A0A0K0XX37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1579979:WM2015 RS02830
gene id: 1579979:WM2015_RS02830
uniprot id: A0A0K0XTJ7
names: Similarity
messages: Belongs to the GSP N family.

1579979:WM2015 RS11660
gene id: 1579979:WM2015_RS11660
uniprot id: A0A0K0XYF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1579979:WM2015 RS13265
gene id: 1579979:WM2015_RS13265
uniprot id: A0A0K0XZ67
names: Similarity
messages: Belongs to the malic enzymes family.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1579979:WM2015 RS10165
gene id: 1579979:WM2015_RS10165
uniprot id: A0A0K0XXE8
names: Similarity
messages: Belongs to the PspA/IM30 family.

1579979:WM2015 RS08655
gene id: 1579979:WM2015_RS08655
uniprot id: A0A0K0XWT3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1579979:WM2015 RS05605
gene id: 1579979:WM2015_RS05605
uniprot id: A0A0K0XUZ7
names: Similarity
messages: Belongs to the PrpF family.

1579979:WM2015 RS11570
gene id: 1579979:WM2015_RS11570
uniprot id: A0A0K0XY76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1579979:WM2015 RS14595
gene id: 1579979:WM2015_RS14595
uniprot id: A0A0K0XZY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1579979:WM2015 RS10775
gene id: 1579979:WM2015_RS10775
uniprot id: A0A0K0XXU2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS00565
gene id: 1579979:WM2015_RS00565
uniprot id: A0A0K0XS70
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1579979:WM2015 RS02550
gene id: 1579979:WM2015_RS02550
uniprot id: A0A0K0XTA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS08275
gene id: 1579979:WM2015_RS08275
uniprot id: A0A0K0XWC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1579979:WM2015 RS15045
gene id: 1579979:WM2015_RS15045
uniprot id: A0A0K0Y074
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1579979:WM2015 RS02380
gene id: 1579979:WM2015_RS02380
uniprot id: A0A0K0XTA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1579979:WM2015 RS09105
gene id: 1579979:WM2015_RS09105
uniprot id: A0A0K0XWW4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS03735
gene id: 1579979:WM2015_RS03735
uniprot id: A0A0K0XTW4
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS00150
gene id: 1579979:WM2015_RS00150
uniprot id: A0A0K0XS22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1579979:WM2015 RS03805
gene id: 1579979:WM2015_RS03805
uniprot id: A0A0K0XU30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1579979:WM2015 RS05495
gene id: 1579979:WM2015_RS05495
uniprot id: A0A0K0XUT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1579979:WM2015 RS10800
gene id: 1579979:WM2015_RS10800
uniprot id: A0A0K0XXS3
names: Similarity
messages: Belongs to the peptidase S8 family.

1579979:WM2015 RS02920
gene id: 1579979:WM2015_RS02920
uniprot id: A0A0K0XTC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1579979:WM2015 RS01330
gene id: 1579979:WM2015_RS01330
uniprot id: A0A0K0XSL3
names: Similarity
messages: Belongs to the citrate synthase family.

1579979:WM2015 RS09460
gene id: 1579979:WM2015_RS09460
uniprot id: A0A0K0XX78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1579979:WM2015 RS03360
gene id: 1579979:WM2015_RS03360
uniprot id: A0A0K0XTV1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1579979:WM2015 RS03230
gene id: 1579979:WM2015_RS03230
uniprot id: A0A0K0XTN9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1579979:WM2015 RS14705
gene id: 1579979:WM2015_RS14705
uniprot id: A0A0K0Y057
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS01535
gene id: 1579979:WM2015_RS01535
uniprot id: A0A0K0XST1
names: Similarity
messages: Belongs to the LOG family.

1579979:WM2015 RS00725
gene id: 1579979:WM2015_RS00725
uniprot id: A0A0K0XSD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1579979:WM2015 RS04765
gene id: 1579979:WM2015_RS04765
uniprot id: A0A0K0XUN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

1579979:WM2015 RS13085
gene id: 1579979:WM2015_RS13085
uniprot id: A0A0K0XZ29
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1579979:WM2015 RS01845
gene id: 1579979:WM2015_RS01845
uniprot id: A0A0K0XT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1579979:WM2015 RS07710
gene id: 1579979:WM2015_RS07710
uniprot id: A0A0K0XW96
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1579979:WM2015 RS14545
gene id: 1579979:WM2015_RS14545
uniprot id: A0A0K0XZY1
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS03665
gene id: 1579979:WM2015_RS03665
uniprot id: A0A0K0XTR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1579979:WM2015 RS11915
gene id: 1579979:WM2015_RS11915
uniprot id: A0A0K0XYF3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1579979:WM2015 RS13530
gene id: 1579979:WM2015_RS13530
uniprot id: A0A0K0XZD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1579979:WM2015 RS12330
gene id: 1579979:WM2015_RS12330
uniprot id: A0A0K0XYQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1579979:WM2015 RS06720
gene id: 1579979:WM2015_RS06720
uniprot id: A0A0K0XVL8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1579979:WM2015 RS05940
gene id: 1579979:WM2015_RS05940
uniprot id: A0A0K0XVB1
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS07985
gene id: 1579979:WM2015_RS07985
uniprot id: A0A0K0XWF4
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1579979:WM2015 RS06500
gene id: 1579979:WM2015_RS06500
uniprot id: A0A0K0XVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1579979:WM2015 RS09275
gene id: 1579979:WM2015_RS09275
uniprot id: A0A0K0XWW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1579979:WM2015 RS03085
gene id: 1579979:WM2015_RS03085
uniprot id: A0A0K0XTP9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1579979:WM2015 RS01010
gene id: 1579979:WM2015_RS01010
uniprot id: A0A0K0XSC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1579979:WM2015 RS01155
gene id: 1579979:WM2015_RS01155
uniprot id: A0A0K0XSL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1579979:WM2015 RS02255
gene id: 1579979:WM2015_RS02255
uniprot id: A0A0K0XT82
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1579979:WM2015 RS00460
gene id: 1579979:WM2015_RS00460
uniprot id: A0A0K0XRZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1579979:WM2015 RS11920
gene id: 1579979:WM2015_RS11920
uniprot id: A0A0K0XYH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1579979:WM2015 RS02615
gene id: 1579979:WM2015_RS02615
uniprot id: A0A0K0XT88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1579979:WM2015 RS01855
gene id: 1579979:WM2015_RS01855
uniprot id: A0A0K0XSU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1579979:WM2015 RS10440
gene id: 1579979:WM2015_RS10440
uniprot id: A0A0K0XXM0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1579979:WM2015 RS07930
gene id: 1579979:WM2015_RS07930
uniprot id: A0A0K0XW85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1579979:WM2015 RS10815
gene id: 1579979:WM2015_RS10815
uniprot id: A0A0K0XXZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1579979:WM2015 RS12630
gene id: 1579979:WM2015_RS12630
uniprot id: A0A0K0XYV7
names: Similarity
messages: Belongs to the peptidase S49 family.

1579979:WM2015 RS10520
gene id: 1579979:WM2015_RS10520
uniprot id: A0A0K0XXL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1579979:WM2015 RS02200
gene id: 1579979:WM2015_RS02200
uniprot id: A0A0K0XT76
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS12685
gene id: 1579979:WM2015_RS12685
uniprot id: A0A0K0XZ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1579979:WM2015 RS08740
gene id: 1579979:WM2015_RS08740
uniprot id: A0A0K0XWT4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1579979:WM2015 RS11510
gene id: 1579979:WM2015_RS11510
uniprot id: A0A0K0XYD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1579979:WM2015 RS07165
gene id: 1579979:WM2015_RS07165
uniprot id: A0A0K0XVQ4
names: Cofactor
messages: Can also use Mn(2+) ion.

1579979:WM2015 RS02585
gene id: 1579979:WM2015_RS02585
uniprot id: A0A0K0XTE7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1579979:WM2015 RS11120
gene id: 1579979:WM2015_RS11120
uniprot id: A0A0K0XXY1
names: Similarity
messages: Belongs to the PhzF family.

1579979:WM2015 RS11950
gene id: 1579979:WM2015_RS11950
uniprot id: A0A0K0XYM2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1579979:WM2015 RS09570
gene id: 1579979:WM2015_RS09570
uniprot id: A0A0K0XX44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS05725
gene id: 1579979:WM2015_RS05725
uniprot id: A0A0K0XUX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS01775
gene id: 1579979:WM2015_RS01775
uniprot id: A0A0K0XSY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1579979:WM2015 RS11940
gene id: 1579979:WM2015_RS11940
uniprot id: A0A0K0XYI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1579979:WM2015 RS06680
gene id: 1579979:WM2015_RS06680
uniprot id: A0A0K0XVQ0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1579979:WM2015 RS07815
gene id: 1579979:WM2015_RS07815
uniprot id: A0A0K0XWA7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1579979:WM2015 RS10095
gene id: 1579979:WM2015_RS10095
uniprot id: A0A0K0XXF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1579979:WM2015 RS14475
gene id: 1579979:WM2015_RS14475
uniprot id: A0A0K0XZX0
names: Similarity
messages: Belongs to the RelE toxin family.

1579979:WM2015 RS04355
gene id: 1579979:WM2015_RS04355
uniprot id: A0A0K0XU91
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1579979:WM2015 RS06630
gene id: 1579979:WM2015_RS06630
uniprot id: A0A0K0XVH7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1579979:WM2015 RS09685
gene id: 1579979:WM2015_RS09685
uniprot id: A0A0K0XXC1
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS07455
gene id: 1579979:WM2015_RS07455
uniprot id: A0A0K0XW47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1579979:WM2015 RS09330
gene id: 1579979:WM2015_RS09330
uniprot id: A0A0K0XX15
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1579979:WM2015 RS01585
gene id: 1579979:WM2015_RS01585
uniprot id: A0A0K0XSV4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1579979:WM2015 RS04890
gene id: 1579979:WM2015_RS04890
uniprot id: A0A0K0XUL4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS02595
gene id: 1579979:WM2015_RS02595
uniprot id: A0A0K0XT59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1579979:WM2015 RS16010
gene id: 1579979:WM2015_RS16010
uniprot id: A0A0K0XT01
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

1579979:WM2015 RS00015
gene id: 1579979:WM2015_RS00015
uniprot id: A0A0K0XRQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1579979:WM2015 RS15025
gene id: 1579979:WM2015_RS15025
uniprot id: A0A0K0Y067
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS00060
gene id: 1579979:WM2015_RS00060
uniprot id: A0A0K0XRT3
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1579979:WM2015 RS07810
gene id: 1579979:WM2015_RS07810
uniprot id: A0A0K0XWB9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1579979:WM2015 RS06830
gene id: 1579979:WM2015_RS06830
uniprot id: A0A0K0XVS9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

1579979:WM2015 RS09280
gene id: 1579979:WM2015_RS09280
uniprot id: A0A0K0XX05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1579979:WM2015 RS04585
gene id: 1579979:WM2015_RS04585
uniprot id: A0A0K0XUF5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1579979:WM2015 RS15410
gene id: 1579979:WM2015_RS15410
uniprot id: A0A0K0Y0E7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS14575
gene id: 1579979:WM2015_RS14575
uniprot id: A0A0K0Y002
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.

1579979:WM2015 RS05165
gene id: 1579979:WM2015_RS05165
uniprot id: A0A0K0XUR3
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1579979:WM2015 RS02400
gene id: 1579979:WM2015_RS02400
uniprot id: A0A0K0XT74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1579979:WM2015 RS04960
gene id: 1579979:WM2015_RS04960
uniprot id: A0A0K0XUR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1579979:WM2015 RS06650
gene id: 1579979:WM2015_RS06650
uniprot id: A0A0K0XVM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1579979:WM2015 RS11680
gene id: 1579979:WM2015_RS11680
uniprot id: A0A0K0XYG0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1579979:WM2015 RS04240
gene id: 1579979:WM2015_RS04240
uniprot id: A0A0K0XUD3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1579979:WM2015 RS05265
gene id: 1579979:WM2015_RS05265
uniprot id: A0A0K0XUT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1579979:WM2015 RS01620
gene id: 1579979:WM2015_RS01620
uniprot id: A0A0K0XSW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1579979:WM2015 RS07760
gene id: 1579979:WM2015_RS07760
uniprot id: A0A0K0XWA6
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1579979:WM2015 RS14005
gene id: 1579979:WM2015_RS14005
uniprot id: A0A0K0XZN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS03945
gene id: 1579979:WM2015_RS03945
uniprot id: A0A0K0XU21
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS00520
gene id: 1579979:WM2015_RS00520
uniprot id: A0A0K0XS97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1579979:WM2015 RS06550
gene id: 1579979:WM2015_RS06550
uniprot id: A0A0K0XVL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1579979:WM2015 RS04750
gene id: 1579979:WM2015_RS04750
uniprot id: A0A0K0XUG6
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS11900
gene id: 1579979:WM2015_RS11900
uniprot id: A0A0K0XYL2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1579979:WM2015 RS09640
gene id: 1579979:WM2015_RS09640
uniprot id: A0A0K0XX56
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1579979:WM2015 RS07050
gene id: 1579979:WM2015_RS07050
uniprot id: A0A0K0XVW6
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS09825
gene id: 1579979:WM2015_RS09825
uniprot id: A0A0K0XXH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1579979:WM2015 RS00620
gene id: 1579979:WM2015_RS00620
uniprot id: A0A0K0XSB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1579979:WM2015 RS01145
gene id: 1579979:WM2015_RS01145
uniprot id: A0A0K0XSI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1579979:WM2015 RS11540
gene id: 1579979:WM2015_RS11540
uniprot id: A0A0K0XY85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1579979:WM2015 RS09245
gene id: 1579979:WM2015_RS09245
uniprot id: A0A0K0XWY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1579979:WM2015 RS08835
gene id: 1579979:WM2015_RS08835
uniprot id: A0A0K0XWN0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1579979:WM2015 RS08500
gene id: 1579979:WM2015_RS08500
uniprot id: A0A0K0XWJ8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1579979:WM2015 RS08770
gene id: 1579979:WM2015_RS08770
uniprot id: A0A0K0XWT9
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1579979:WM2015 RS00065
gene id: 1579979:WM2015_RS00065
uniprot id: A0A0K0XRR1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS08815
gene id: 1579979:WM2015_RS08815
uniprot id: A0A0K0XWW0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1579979:WM2015 RS11165
gene id: 1579979:WM2015_RS11165
uniprot id: A0A0K0XY09
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1579979:WM2015 RS06800
gene id: 1579979:WM2015_RS06800
uniprot id: A0A0K0XVS8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1579979:WM2015 RS01440
gene id: 1579979:WM2015_RS01440
uniprot id: A0A0K0XSR1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1579979:WM2015 RS08345
gene id: 1579979:WM2015_RS08345
uniprot id: A0A0K0XWK8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS12230
gene id: 1579979:WM2015_RS12230
uniprot id: A0A0K0XYN0
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS08680
gene id: 1579979:WM2015_RS08680
uniprot id: A0A0K0XWT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1579979:WM2015 RS03285
gene id: 1579979:WM2015_RS03285
uniprot id: A0A0K0XTT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS03845
gene id: 1579979:WM2015_RS03845
uniprot id: A0A0K0XU08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1579979:WM2015 RS09620
gene id: 1579979:WM2015_RS09620
uniprot id: A0A0K0XX52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1579979:WM2015 RS06690
gene id: 1579979:WM2015_RS06690
uniprot id: A0A0K0XVI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1579979:WM2015 RS13510
gene id: 1579979:WM2015_RS13510
uniprot id: A0A0K0XZI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1579979:WM2015 RS00930
gene id: 1579979:WM2015_RS00930
uniprot id: A0A0K0XSH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1579979:WM2015 RS07885
gene id: 1579979:WM2015_RS07885
uniprot id: A0A0K0XWD3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1579979:WM2015 RS00260
gene id: 1579979:WM2015_RS00260
uniprot id: A0A0K0XRX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS03990
gene id: 1579979:WM2015_RS03990
uniprot id: A0A0K0XTY5
names: Similarity
messages: Belongs to the SecB family.

1579979:WM2015 RS03355
gene id: 1579979:WM2015_RS03355
uniprot id: A0A0K0XTR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1579979:WM2015 RS00085
gene id: 1579979:WM2015_RS00085
uniprot id: A0A0K0XRT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1579979:WM2015 RS11590
gene id: 1579979:WM2015_RS11590
uniprot id: A0A0K0XY94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1579979:WM2015 RS02405
gene id: 1579979:WM2015_RS02405
uniprot id: A0A0K0XTB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1579979:WM2015 RS06655
gene id: 1579979:WM2015_RS06655
uniprot id: A0A0K0XVI1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1579979:WM2015 RS11550
gene id: 1579979:WM2015_RS11550
uniprot id: A0A0K0XY98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1579979:WM2015 RS02030
gene id: 1579979:WM2015_RS02030
uniprot id: A0A0K0XSX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1579979:WM2015 RS08675
gene id: 1579979:WM2015_RS08675
uniprot id: A0A0K0XWN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1579979:WM2015 RS06140
gene id: 1579979:WM2015_RS06140
uniprot id: A0A0K0XVE6
names: Similarity
messages: Belongs to the elongation factor P family.

1579979:WM2015 RS06200
gene id: 1579979:WM2015_RS06200
uniprot id: A0A0K0XVB5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS03225
gene id: 1579979:WM2015_RS03225
uniprot id: A0A0K0XTI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS06065
gene id: 1579979:WM2015_RS06065
uniprot id: A0A0K0XVD1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1579979:WM2015 RS12485
gene id: 1579979:WM2015_RS12485
uniprot id: A0A0K0XYQ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS11960
gene id: 1579979:WM2015_RS11960
uniprot id: A0A0K0XYG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1579979:WM2015 RS10780
gene id: 1579979:WM2015_RS10780
uniprot id: A0A0K0XY10
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

1579979:WM2015 RS00705
gene id: 1579979:WM2015_RS00705
uniprot id: A0A0K0XSD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1579979:WM2015 RS02005
gene id: 1579979:WM2015_RS02005
uniprot id: A0A0K0XSX1
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

1579979:WM2015 RS01675
gene id: 1579979:WM2015_RS01675
uniprot id: A0A0K0XSW9
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS03045
gene id: 1579979:WM2015_RS03045
uniprot id: A0A0K0XTF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1579979:WM2015 RS04215
gene id: 1579979:WM2015_RS04215
uniprot id: A0A0K0XUC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1579979:WM2015 RS02090
gene id: 1579979:WM2015_RS02090
uniprot id: A0A0K0XT15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1579979:WM2015 RS08290
gene id: 1579979:WM2015_RS08290
uniprot id: A0A0K0XWJ7
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1579979:WM2015 RS12885
gene id: 1579979:WM2015_RS12885
uniprot id: A0A0K0XZ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1579979:WM2015 RS10020
gene id: 1579979:WM2015_RS10020
uniprot id: A0A0K0XXD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1579979:WM2015 RS06555
gene id: 1579979:WM2015_RS06555
uniprot id: A0A0K0XVK9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS07705
gene id: 1579979:WM2015_RS07705
uniprot id: A0A0K0XW40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1579979:WM2015 RS03205
gene id: 1579979:WM2015_RS03205
uniprot id: A0A0K0XTN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1579979:WM2015 RS10355
gene id: 1579979:WM2015_RS10355
uniprot id: A0A0K0XXS2
names: Similarity
messages: Belongs to the TrpF family.

1579979:WM2015 RS07955
gene id: 1579979:WM2015_RS07955
uniprot id: A0A0K0XW90
names: Similarity
messages: Belongs to the fabD family.

1579979:WM2015 RS09670
gene id: 1579979:WM2015_RS09670
uniprot id: A0A0K0XX51
names: Similarity
messages: Belongs to the CFA/CMAS family.

1579979:WM2015 RS15095
gene id: 1579979:WM2015_RS15095
uniprot id: A0A0K0Y084
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1579979:WM2015 RS07750
gene id: 1579979:WM2015_RS07750
uniprot id: A0A0K0XW17
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1579979:WM2015 RS00590
gene id: 1579979:WM2015_RS00590
uniprot id: A0A0K0XS76
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1579979:WM2015 RS12200
gene id: 1579979:WM2015_RS12200
uniprot id: A0A0K0XYK4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1579979:WM2015 RS01300
gene id: 1579979:WM2015_RS01300
uniprot id: A0A0K0XSK9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1579979:WM2015 RS15080
gene id: 1579979:WM2015_RS15080
uniprot id: A0A0K0Y0F5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1579979:WM2015 RS02040
gene id: 1579979:WM2015_RS02040
uniprot id: A0A0K0XT05
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1579979:WM2015 RS02930
gene id: 1579979:WM2015_RS02930
uniprot id: A0A0K0XTL6
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

1579979:WM2015 RS02815
gene id: 1579979:WM2015_RS02815
uniprot id: A0A0K0XTD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS08670
gene id: 1579979:WM2015_RS08670
uniprot id: A0A0K0XWK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1579979:WM2015 RS03620
gene id: 1579979:WM2015_RS03620
uniprot id: A0A0K0XTW3
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS06365
gene id: 1579979:WM2015_RS06365
uniprot id: A0A0K0XVA3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1579979:WM2015 RS10945
gene id: 1579979:WM2015_RS10945
uniprot id: A0A0K0XXW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1579979:WM2015 RS04690
gene id: 1579979:WM2015_RS04690
uniprot id: A0A0K0XUM4
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS01365
gene id: 1579979:WM2015_RS01365
uniprot id: A0A0K0XSP7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1579979:WM2015 RS14345
gene id: 1579979:WM2015_RS14345
uniprot id: A0A0K0XZU9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1579979:WM2015 RS13090
gene id: 1579979:WM2015_RS13090
uniprot id: A0A0K0XZ30
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1579979:WM2015 RS10750
gene id: 1579979:WM2015_RS10750
uniprot id: A0A0K0XXT8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS02425
gene id: 1579979:WM2015_RS02425
uniprot id: A0A0K0XT81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1579979:WM2015 RS10360
gene id: 1579979:WM2015_RS10360
uniprot id: A0A0K0XXQ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS00715
gene id: 1579979:WM2015_RS00715
uniprot id: A0A0K0XS45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1579979:WM2015 RS11270
gene id: 1579979:WM2015_RS11270
uniprot id: A0A0K0XY14
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS07835
gene id: 1579979:WM2015_RS07835
uniprot id: A0A0K0XWC4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1579979:WM2015 RS13765
gene id: 1579979:WM2015_RS13765
uniprot id: A0A0K0XZL6
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS02355
gene id: 1579979:WM2015_RS02355
uniprot id: A0A0K0XTA2
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS06670
gene id: 1579979:WM2015_RS06670
uniprot id: A0A0K0XVQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS14175
gene id: 1579979:WM2015_RS14175
uniprot id: A0A0K0XZV4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1579979:WM2015 RS01595
gene id: 1579979:WM2015_RS01595
uniprot id: A0A0K0XSQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1579979:WM2015 RS01715
gene id: 1579979:WM2015_RS01715
uniprot id: A0A0K0XSU3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1579979:WM2015 RS02225
gene id: 1579979:WM2015_RS02225
uniprot id: A0A0K0XT80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS09595
gene id: 1579979:WM2015_RS09595
uniprot id: A0A0K0XX48
names: Similarity
messages: Belongs to the thioredoxin family.

1579979:WM2015 RS01105
gene id: 1579979:WM2015_RS01105
uniprot id: A0A0K0XSE7
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS10375
gene id: 1579979:WM2015_RS10375
uniprot id: A0A0K0XXL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1579979:WM2015 RS14675
gene id: 1579979:WM2015_RS14675
uniprot id: A0A0K0Y075
names: Similarity
messages: Belongs to the UPF0145 family.

1579979:WM2015 RS00075
gene id: 1579979:WM2015_RS00075
uniprot id: A0A0K0XS07
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS10030
gene id: 1579979:WM2015_RS10030
uniprot id: A0A0K0XXI7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1579979:WM2015 RS09425
gene id: 1579979:WM2015_RS09425
uniprot id: A0A0K0XX31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1579979:WM2015 RS09755
gene id: 1579979:WM2015_RS09755
uniprot id: A0A0K0XXF4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1579979:WM2015 RS00430
gene id: 1579979:WM2015_RS00430
uniprot id: A0A0K0XS12
names: Cofactor
messages: Binds 1 FAD per subunit.

1579979:WM2015 RS06665
gene id: 1579979:WM2015_RS06665
uniprot id: A0A0K0XVK8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS03330
gene id: 1579979:WM2015_RS03330
uniprot id: A0A0K0XTQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1579979:WM2015 RS09285
gene id: 1579979:WM2015_RS09285
uniprot id: A0A0K0XX59
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1579979:WM2015 RS03235
gene id: 1579979:WM2015_RS03235
uniprot id: A0A0K0XTS7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1579979:WM2015 RS12520
gene id: 1579979:WM2015_RS12520
uniprot id: A0A0K0XYT7
names: Similarity
messages: Belongs to the peptidase M1 family.

1579979:WM2015 RS02705
gene id: 1579979:WM2015_RS02705
uniprot id: A0A0K0XTH2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1579979:WM2015 RS08205
gene id: 1579979:WM2015_RS08205
uniprot id: A0A0K0XWJ9
names: Similarity
messages: Belongs to the HSP15 family.

1579979:WM2015 RS09255
gene id: 1579979:WM2015_RS09255
uniprot id: A0A0K0XWY8
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS06430
gene id: 1579979:WM2015_RS06430
uniprot id: A0A0K0XVE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine.

1579979:WM2015 RS01670
gene id: 1579979:WM2015_RS01670
uniprot id: A0A0K0XSX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1579979:WM2015 RS02375
gene id: 1579979:WM2015_RS02375
uniprot id: A0A0K0XTB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1579979:WM2015 RS02180
gene id: 1579979:WM2015_RS02180
uniprot id: A0A0K0XT68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1579979:WM2015 RS01485
gene id: 1579979:WM2015_RS01485
uniprot id: A0A0K0XSR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1579979:WM2015 RS15450
gene id: 1579979:WM2015_RS15450
uniprot id: A0A0K0Y0L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1579979:WM2015 RS13950
gene id: 1579979:WM2015_RS13950
uniprot id: A0A0K0XZL0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1579979:WM2015 RS11290
gene id: 1579979:WM2015_RS11290
uniprot id: A0A0K0XY33
names: Similarity
messages: Belongs to the UPF0102 family.

1579979:WM2015 RS06540
gene id: 1579979:WM2015_RS06540
uniprot id: A0A0K0XVD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1579979:WM2015 RS11595
gene id: 1579979:WM2015_RS11595
uniprot id: A0A0K0XY84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1579979:WM2015 RS11185
gene id: 1579979:WM2015_RS11185
uniprot id: A0A0K0XY68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1579979:WM2015 RS02205
gene id: 1579979:WM2015_RS02205
uniprot id: A0A0K0XT73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1579979:WM2015 RS10380
gene id: 1579979:WM2015_RS10380
uniprot id: A0A0K0XXS8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1579979:WM2015 RS08870
gene id: 1579979:WM2015_RS08870
uniprot id: A0A0K0XWR7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1579979:WM2015 RS11320
gene id: 1579979:WM2015_RS11320
uniprot id: A0A0K0XY24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1579979:WM2015 RS12260
gene id: 1579979:WM2015_RS12260
uniprot id: A0A0K0XYT4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1579979:WM2015 RS15000
gene id: 1579979:WM2015_RS15000
uniprot id: A0A0K0Y065
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS07715
gene id: 1579979:WM2015_RS07715
uniprot id: A0A0K0XW88
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS12345
gene id: 1579979:WM2015_RS12345
uniprot id: A0A0K0XYN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1579979:WM2015 RS09180
gene id: 1579979:WM2015_RS09180
uniprot id: A0A0K0XWX7
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS01395
gene id: 1579979:WM2015_RS01395
uniprot id: A0A0K0XSK1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS08310
gene id: 1579979:WM2015_RS08310
uniprot id: A0A0K0XWL8
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1579979:WM2015 RS02640
gene id: 1579979:WM2015_RS02640
uniprot id: A0A0K0XT93
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1579979:WM2015 RS00415
gene id: 1579979:WM2015_RS00415
uniprot id: A0A0K0XS43
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1579979:WM2015 RS02825
gene id: 1579979:WM2015_RS02825
uniprot id: A0A0K0XTG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1579979:WM2015 RS13715
gene id: 1579979:WM2015_RS13715
uniprot id: A0A0K0XZK6
names: Similarity
messages: Belongs to the YggT family.

1579979:WM2015 RS02940
gene id: 1579979:WM2015_RS02940
uniprot id: A0A0K0XTF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1579979:WM2015 RS06875
gene id: 1579979:WM2015_RS06875
uniprot id: A0A0K0XVU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1579979:WM2015 RS09785
gene id: 1579979:WM2015_RS09785
uniprot id: A0A0K0XXE1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1579979:WM2015 RS15445
gene id: 1579979:WM2015_RS15445
uniprot id: A0A0K0Y0G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1579979:WM2015 RS15420
gene id: 1579979:WM2015_RS15420
uniprot id: A0A0K0Y0L0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1579979:WM2015 RS10840
gene id: 1579979:WM2015_RS10840
uniprot id: A0A0K0XXU8
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1579979:WM2015 RS03655
gene id: 1579979:WM2015_RS03655
uniprot id: A0A0K0XU07
names: Similarity
messages: Belongs to the CFA/CMAS family.

1579979:WM2015 RS03000
gene id: 1579979:WM2015_RS03000
uniprot id: A0A0K0XTJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1579979:WM2015 RS10540
gene id: 1579979:WM2015_RS10540
uniprot id: A0A0K0XXP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1579979:WM2015 RS12070
gene id: 1579979:WM2015_RS12070
uniprot id: A0A0K0XYP6
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS05600
gene id: 1579979:WM2015_RS05600
uniprot id: A0A0K0XUV3
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1579979:WM2015 RS02165
gene id: 1579979:WM2015_RS02165
uniprot id: A0A0K0XSX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1579979:WM2015 RS09260
gene id: 1579979:WM2015_RS09260
uniprot id: A0A0K0XX35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1579979:WM2015 RS07405
gene id: 1579979:WM2015_RS07405
uniprot id: A0A0K0XW38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1579979:WM2015 RS13140
gene id: 1579979:WM2015_RS13140
uniprot id: A0A0K0XZ40
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS03060
gene id: 1579979:WM2015_RS03060
uniprot id: A0A0K0XTP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1579979:WM2015 RS10655
gene id: 1579979:WM2015_RS10655
uniprot id: A0A0K0XXY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS11485
gene id: 1579979:WM2015_RS11485
uniprot id: A0A0K0XYC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1579979:WM2015 RS07875
gene id: 1579979:WM2015_RS07875
uniprot id: A0A0K0XW42
names: Similarity
messages: Belongs to the YfgM family.

1579979:WM2015 RS10820
gene id: 1579979:WM2015_RS10820
uniprot id: A0A0K0XXU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1579979:WM2015 RS01865
gene id: 1579979:WM2015_RS01865
uniprot id: A0A0K0XSW8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS08905
gene id: 1579979:WM2015_RS08905
uniprot id: A0A0K0XWW3
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS07060
gene id: 1579979:WM2015_RS07060
uniprot id: A0A0K0XVP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS11665
gene id: 1579979:WM2015_RS11665
uniprot id: A0A0K0XYB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1579979:WM2015 RS12335
gene id: 1579979:WM2015_RS12335
uniprot id: A0A0K0XYV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1579979:WM2015 RS03445
gene id: 1579979:WM2015_RS03445
uniprot id: A0A0K0XTW6
names: Similarity
messages: Belongs to the ArsC family.

1579979:WM2015 RS02045
gene id: 1579979:WM2015_RS02045
uniprot id: A0A0K0XT48
names: Similarity
messages: Belongs to the glutamate synthase family.

1579979:WM2015 RS03215
gene id: 1579979:WM2015_RS03215
uniprot id: A0A0K0XTS3
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS04715
gene id: 1579979:WM2015_RS04715
uniprot id: A0A0K0XUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS10370
gene id: 1579979:WM2015_RS10370
uniprot id: A0A0K0XXJ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS08100
gene id: 1579979:WM2015_RS08100
uniprot id: A0A0K0XWC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1579979:WM2015 RS05145
gene id: 1579979:WM2015_RS05145
uniprot id: A0A0K0XUV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1579979:WM2015 RS08125
gene id: 1579979:WM2015_RS08125
uniprot id: A0A0K0XWC6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1579979:WM2015 RS04265
gene id: 1579979:WM2015_RS04265
uniprot id: A0A0K0XUD8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1579979:WM2015 RS13770
gene id: 1579979:WM2015_RS13770
uniprot id: A0A0K0XZG8
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS07065
gene id: 1579979:WM2015_RS07065
uniprot id: A0A0K0XVS1
names: Similarity
messages: Belongs to the UPF0047 family.

1579979:WM2015 RS11975
gene id: 1579979:WM2015_RS11975
uniprot id: A0A0K0XYM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1579979:WM2015 RS15255
gene id: 1579979:WM2015_RS15255
uniprot id: A0A0K0Y0I5
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1579979:WM2015 RS11335
gene id: 1579979:WM2015_RS11335
uniprot id: A0A0K0XY95
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1579979:WM2015 RS04525
gene id: 1579979:WM2015_RS04525
uniprot id: A0A0K0XUC1
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS01910
gene id: 1579979:WM2015_RS01910
uniprot id: A0A0K0XSS8
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS10920
gene id: 1579979:WM2015_RS10920
uniprot id: A0A0K0XXW3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1579979:WM2015 RS08330
gene id: 1579979:WM2015_RS08330
uniprot id: A0A0K0XWD4
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1579979:WM2015 RS15115
gene id: 1579979:WM2015_RS15115
uniprot id: A0A0K0Y082
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1579979:WM2015 RS02905
gene id: 1579979:WM2015_RS02905
uniprot id: A0A0K0XTL1
names: Similarity
messages: Belongs to the UPF0276 family.

1579979:WM2015 RS11340
gene id: 1579979:WM2015_RS11340
uniprot id: A0A0K0XY41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS08765
gene id: 1579979:WM2015_RS08765
uniprot id: A0A0K0XWV0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS06915
gene id: 1579979:WM2015_RS06915
uniprot id: A0A0K0XVU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1579979:WM2015 RS11675
gene id: 1579979:WM2015_RS11675
uniprot id: A0A0K0XYC2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1579979:WM2015 RS08685
gene id: 1579979:WM2015_RS08685
uniprot id: A0A0K0XWS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1579979:WM2015 RS02000
gene id: 1579979:WM2015_RS02000
uniprot id: A0A0K0XT33
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS04445
gene id: 1579979:WM2015_RS04445
uniprot id: A0A0K0XUG9
names: Similarity
messages: Belongs to the Gfa family.

1579979:WM2015 RS03925
gene id: 1579979:WM2015_RS03925
uniprot id: A0A0K0XU51
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS11360
gene id: 1579979:WM2015_RS11360
uniprot id: A0A0K0XYA1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1579979:WM2015 RS11670
gene id: 1579979:WM2015_RS11670
uniprot id: A0A0K0XY99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1579979:WM2015 RS00005
gene id: 1579979:WM2015_RS00005
uniprot id: A0A0K0XRZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1579979:WM2015 RS14405
gene id: 1579979:WM2015_RS14405
uniprot id: A0A0K0Y016
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1579979:WM2015 RS11470
gene id: 1579979:WM2015_RS11470
uniprot id: A0A0K0XY57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1579979:WM2015 RS06445
gene id: 1579979:WM2015_RS06445
uniprot id: A0A0K0XVJ5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1579979:WM2015 RS14645
gene id: 1579979:WM2015_RS14645
uniprot id: A0A0K0Y018
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1579979:WM2015 RS02295
gene id: 1579979:WM2015_RS02295
uniprot id: A0A0K0XT55
names: PTM
messages: Binds 1 heme group per subunit.

1579979:WM2015 RS13755
gene id: 1579979:WM2015_RS13755
uniprot id: A0A0K0XZI2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1579979:WM2015 RS09150
gene id: 1579979:WM2015_RS09150
uniprot id: A0A0K0XWU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1579979:WM2015 RS16045
gene id: 1579979:WM2015_RS16045
uniprot id: A0A0K0XXH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1579979:WM2015 RS09415
gene id: 1579979:WM2015_RS09415
uniprot id: A0A0K0XX22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS04820
gene id: 1579979:WM2015_RS04820
uniprot id: A0A0K0XUP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1579979:WM2015 RS09310
gene id: 1579979:WM2015_RS09310
uniprot id: A0A0K0XX64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1579979:WM2015 RS11020
gene id: 1579979:WM2015_RS11020
uniprot id: A0A0K0XY42
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1579979:WM2015 RS05985
gene id: 1579979:WM2015_RS05985
uniprot id: A0A0K0XV70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1579979:WM2015 RS08250
gene id: 1579979:WM2015_RS08250
uniprot id: A0A0K0XWB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1579979:WM2015 RS00035
gene id: 1579979:WM2015_RS00035
uniprot id: A0A0K0XRS8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1579979:WM2015 RS02590
gene id: 1579979:WM2015_RS02590
uniprot id: A0A0K0XT83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1579979:WM2015 RS05905
gene id: 1579979:WM2015_RS05905
uniprot id: A0A0K0XV12
names: Similarity
messages: Belongs to the peptidase S9C family.

1579979:WM2015 RS08350
gene id: 1579979:WM2015_RS08350
uniprot id: A0A0K0XWG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1579979:WM2015 RS14865
gene id: 1579979:WM2015_RS14865
uniprot id: A0A0K0Y088
names: Similarity
messages: Belongs to the creatininase superfamily.

1579979:WM2015 RS11255
gene id: 1579979:WM2015_RS11255
uniprot id: A0A0K0XY82
names: Similarity
messages: Belongs to the SCO1/2 family.

1579979:WM2015 RS12235
gene id: 1579979:WM2015_RS12235
uniprot id: A0A0K0XYT1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1579979:WM2015 RS06355
gene id: 1579979:WM2015_RS06355
uniprot id: A0A0K0XVI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1579979:WM2015 RS14055
gene id: 1579979:WM2015_RS14055
uniprot id: A0A0K0XZP3
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

1579979:WM2015 RS11535
gene id: 1579979:WM2015_RS11535
uniprot id: A0A0K0XYD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1579979:WM2015 RS01195
gene id: 1579979:WM2015_RS01195
uniprot id: A0A0K0XSI9
names: Similarity
messages: Belongs to the peptidase S41A family.

1579979:WM2015 RS01860
gene id: 1579979:WM2015_RS01860
uniprot id: A0A0K0XSS0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1579979:WM2015 RS10555
gene id: 1579979:WM2015_RS10555
uniprot id: A0A0K0XXW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1579979:WM2015 RS01725
gene id: 1579979:WM2015_RS01725
uniprot id: A0A0K0XSX9
names: Similarity
messages: Belongs to the universal stress protein A family.

1579979:WM2015 RS01445
gene id: 1579979:WM2015_RS01445
uniprot id: A0A0K0XSL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1579979:WM2015 RS13660
gene id: 1579979:WM2015_RS13660
uniprot id: A0A0K0XZL2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1579979:WM2015 RS01900
gene id: 1579979:WM2015_RS01900
uniprot id: A0A0K0XT12
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS09445
gene id: 1579979:WM2015_RS09445
uniprot id: A0A0K0XX16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1579979:WM2015 RS06570
gene id: 1579979:WM2015_RS06570
uniprot id: A0A0K0XVL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1579979:WM2015 RS06525
gene id: 1579979:WM2015_RS06525
uniprot id: A0A0K0XVK6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1579979:WM2015 RS11650
gene id: 1579979:WM2015_RS11650
uniprot id: A0A0K0XYB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1579979:WM2015 RS03020
gene id: 1579979:WM2015_RS03020
uniprot id: A0A0K0XTG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1579979:WM2015 RS09625
gene id: 1579979:WM2015_RS09625
uniprot id: A0A0K0XX58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1579979:WM2015 RS08440
gene id: 1579979:WM2015_RS08440
uniprot id: A0A0K0XWI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1579979:WM2015 RS02215
gene id: 1579979:WM2015_RS02215
uniprot id: A0A0K0XSY2
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1579979:WM2015 RS15455
gene id: 1579979:WM2015_RS15455
uniprot id: A0A0K0Y0J6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1579979:WM2015 RS02650
gene id: 1579979:WM2015_RS02650
uniprot id: A0A0K0XTC6
names: Similarity
messages: Belongs to the peptidase M16 family.

1579979:WM2015 RS03010
gene id: 1579979:WM2015_RS03010
uniprot id: A0A0K0XTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1579979:WM2015 RS02925
gene id: 1579979:WM2015_RS02925
uniprot id: A0A0K0XTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1579979:WM2015 RS02625
gene id: 1579979:WM2015_RS02625
uniprot id: A0A0K0XTB8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1579979:WM2015 RS07700
gene id: 1579979:WM2015_RS07700
uniprot id: A0A0K0XW07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

1579979:WM2015 RS09515
gene id: 1579979:WM2015_RS09515
uniprot id: A0A0K0XX36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1579979:WM2015 RS05260
gene id: 1579979:WM2015_RS05260
uniprot id: A0A0K0XUN5
names: Subcellular Location Annotation
messages: Nucleus

1579979:WM2015 RS08400
gene id: 1579979:WM2015_RS08400
uniprot id: A0A0K0XWG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1579979:WM2015 RS01000
gene id: 1579979:WM2015_RS01000
uniprot id: A0A0K0XSI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1579979:WM2015 RS11455
gene id: 1579979:WM2015_RS11455
uniprot id: A0A0K0XYC3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1579979:WM2015 RS01780
gene id: 1579979:WM2015_RS01780
uniprot id: A0A0K0XST4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1579979:WM2015 RS11545
gene id: 1579979:WM2015_RS11545
uniprot id: A0A0K0XY71
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1579979:WM2015 RS13695
gene id: 1579979:WM2015_RS13695
uniprot id: A0A0K0XZF1
names: Similarity
messages: Belongs to the GSP E family.

1579979:WM2015 RS07245
gene id: 1579979:WM2015_RS07245
uniprot id: A0A0K0XVZ9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1579979:WM2015 RS09325
gene id: 1579979:WM2015_RS09325
uniprot id: A0A0K0XWZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1579979:WM2015 RS10230
gene id: 1579979:WM2015_RS10230
uniprot id: A0A0K0XXM6
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1579979:WM2015 RS03780
gene id: 1579979:WM2015_RS03780
uniprot id: A0A0K0XU26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1579979:WM2015 RS12185
gene id: 1579979:WM2015_RS12185
uniprot id: A0A0K0XYK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1579979:WM2015 RS13745
gene id: 1579979:WM2015_RS13745
uniprot id: A0A0K0XZG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1579979:WM2015 RS10490
gene id: 1579979:WM2015_RS10490
uniprot id: A0A0K0XXN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1579979:WM2015 RS12845
gene id: 1579979:WM2015_RS12845
uniprot id: A0A0K0XZ38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1579979:WM2015 RS09945
gene id: 1579979:WM2015_RS09945
uniprot id: A0A0K0XXC5
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1579979:WM2015 RS13710
gene id: 1579979:WM2015_RS13710
uniprot id: A0A0K0XZM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1579979:WM2015 RS00700
gene id: 1579979:WM2015_RS00700
uniprot id: A0A0K0XSC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1579979:WM2015 RS06700
gene id: 1579979:WM2015_RS06700
uniprot id: A0A0K0XVQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1579979:WM2015 RS08460
gene id: 1579979:WM2015_RS08460
uniprot id: A0A0K0XWG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1579979:WM2015 RS12835
gene id: 1579979:WM2015_RS12835
uniprot id: A0A0K0XYZ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1579979:WM2015 RS02450
gene id: 1579979:WM2015_RS02450
uniprot id: A0A0K0XT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS10265
gene id: 1579979:WM2015_RS10265
uniprot id: A0A0K0XXI1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1579979:WM2015 RS07120
gene id: 1579979:WM2015_RS07120
uniprot id: A0A0K0XVT2
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1579979:WM2015 RS10250
gene id: 1579979:WM2015_RS10250
uniprot id: A0A0K0XXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1579979:WM2015 RS07450
gene id: 1579979:WM2015_RS07450
uniprot id: A0A0K0XVZ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1579979:WM2015 RS10715
gene id: 1579979:WM2015_RS10715
uniprot id: A0A0K0XXS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS03055
gene id: 1579979:WM2015_RS03055
uniprot id: A0A0K0XTP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1579979:WM2015 RS04855
gene id: 1579979:WM2015_RS04855
uniprot id: A0A0K0XUF7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1579979:WM2015 RS06495
gene id: 1579979:WM2015_RS06495
uniprot id: A0A0K0XVG3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1579979:WM2015 RS10235
gene id: 1579979:WM2015_RS10235
uniprot id: A0A0K0XXH6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1579979:WM2015 RS12695
gene id: 1579979:WM2015_RS12695
uniprot id: A0A0K0XYV4
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS11695
gene id: 1579979:WM2015_RS11695
uniprot id: A0A0K0XY84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1579979:WM2015 RS01430
gene id: 1579979:WM2015_RS01430
uniprot id: A0A0K0XSN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1579979:WM2015 RS05335
gene id: 1579979:WM2015_RS05335
uniprot id: A0A0K0XUS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1579979:WM2015 RS01275
gene id: 1579979:WM2015_RS01275
uniprot id: A0A0K0XSK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1579979:WM2015 RS08030
gene id: 1579979:WM2015_RS08030
uniprot id: A0A0K0XWA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1579979:WM2015 RS08705
gene id: 1579979:WM2015_RS08705
uniprot id: A0A0K0XWN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1579979:WM2015 RS00195
gene id: 1579979:WM2015_RS00195
uniprot id: A0A0K0XRZ8
names: Subcellular Location Annotation
messages: Cytoplasm

1579979:WM2015 RS11505
gene id: 1579979:WM2015_RS11505
uniprot id: A0A0K0XYD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1579979:WM2015 RS09010
gene id: 1579979:WM2015_RS09010
uniprot id: A0A0K0XWT7
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1579979:WM2015 RS09940
gene id: 1579979:WM2015_RS09940
uniprot id: A0A0K0XXA2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1579979:WM2015 RS11530
gene id: 1579979:WM2015_RS11530
uniprot id: A0A0K0XYD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1579979:WM2015 RS13145
gene id: 1579979:WM2015_RS13145
uniprot id: A0A0K0XZ55
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS01915
gene id: 1579979:WM2015_RS01915
uniprot id: A0A0K0XSX8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1579979:WM2015 RS09400
gene id: 1579979:WM2015_RS09400
uniprot id: A0A0K0XX06
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1579979:WM2015 RS13345
gene id: 1579979:WM2015_RS13345
uniprot id: A0A0K0XZD6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS00580
gene id: 1579979:WM2015_RS00580
uniprot id: A0A0K0XS42
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS05720
gene id: 1579979:WM2015_RS05720
uniprot id: A0A0K0XV05
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1579979:WM2015 RS10335
gene id: 1579979:WM2015_RS10335
uniprot id: A0A0K0XXP7
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1579979:WM2015 RS10805
gene id: 1579979:WM2015_RS10805
uniprot id: A0A0K0XXU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

1579979:WM2015 RS01500
gene id: 1579979:WM2015_RS01500
uniprot id: A0A0K0XSP4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1579979:WM2015 RS09175
gene id: 1579979:WM2015_RS09175
uniprot id: A0A0K0XWU6
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1579979:WM2015 RS06685
gene id: 1579979:WM2015_RS06685
uniprot id: A0A0K0XVK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1579979:WM2015 RS15400
gene id: 1579979:WM2015_RS15400
uniprot id: A0A0K0Y0I8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1579979:WM2015 RS10850
gene id: 1579979:WM2015_RS10850
uniprot id: A0A0K0XXV7
names: Similarity
messages: Belongs to the UPF0111 family.

1579979:WM2015 RS00445
gene id: 1579979:WM2015_RS00445
uniprot id: A0A0K0XS82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS10530
gene id: 1579979:WM2015_RS10530
uniprot id: A0A0K0XXW0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS09970
gene id: 1579979:WM2015_RS09970
uniprot id: A0A0K0XXD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1579979:WM2015 RS14230
gene id: 1579979:WM2015_RS14230
uniprot id: A0A0K0XZU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1579979:WM2015 RS02890
gene id: 1579979:WM2015_RS02890
uniprot id: A0A0K0XTE4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1579979:WM2015 RS08200
gene id: 1579979:WM2015_RS08200
uniprot id: A0A0K0XWE2
names: Subcellular Location Annotation
messages: Cytoplasm

1579979:WM2015 RS01735
gene id: 1579979:WM2015_RS01735
uniprot id: A0A0K0XSQ3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1579979:WM2015 RS01825
gene id: 1579979:WM2015_RS01825
uniprot id: A0A0K0XSZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1579979:WM2015 RS07625
gene id: 1579979:WM2015_RS07625
uniprot id: A0A0K0XVZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1579979:WM2015 RS09500
gene id: 1579979:WM2015_RS09500
uniprot id: A0A0K0XX39
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1579979:WM2015 RS01810
gene id: 1579979:WM2015_RS01810
uniprot id: A0A0K0XSR3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1579979:WM2015 RS08880
gene id: 1579979:WM2015_RS08880
uniprot id: A0A0K0XWV8
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

1579979:WM2015 RS10935
gene id: 1579979:WM2015_RS10935
uniprot id: A0A0K0XY29
names: Similarity
messages: Belongs to the peptidase S8 family.

1579979:WM2015 RS07480
gene id: 1579979:WM2015_RS07480
uniprot id: A0A0K0XW54
names: Similarity
messages: Belongs to the PhoH family.

1579979:WM2015 RS02995
gene id: 1579979:WM2015_RS02995
uniprot id: A0A0K0XTE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1579979:WM2015 RS10990
gene id: 1579979:WM2015_RS10990
uniprot id: A0A0K0XY39
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1579979:WM2015 RS03190
gene id: 1579979:WM2015_RS03190
uniprot id: A0A0K0XTR8
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1579979:WM2015 RS10320
gene id: 1579979:WM2015_RS10320
uniprot id: A0A0K0XXI0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS08445
gene id: 1579979:WM2015_RS08445
uniprot id: A0A0K0XWP2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1579979:WM2015 RS08340
gene id: 1579979:WM2015_RS08340
uniprot id: A0A0K0XWM3
names: Similarity
messages: Belongs to the universal stress protein A family.

1579979:WM2015 RS01660
gene id: 1579979:WM2015_RS01660
uniprot id: A0A0K0XSP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1579979:WM2015 RS14570
gene id: 1579979:WM2015_RS14570
uniprot id: A0A0K0XZY4
names: Similarity
messages: Belongs to the pirin family.

1579979:WM2015 RS13735
gene id: 1579979:WM2015_RS13735
uniprot id: A0A0K0XZM7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1579979:WM2015 RS01465
gene id: 1579979:WM2015_RS01465
uniprot id: A0A0K0XSL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS00995
gene id: 1579979:WM2015_RS00995
uniprot id: A0A0K0XSF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1579979:WM2015 RS08855
gene id: 1579979:WM2015_RS08855
uniprot id: A0A0K0XWV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1579979:WM2015 RS08450
gene id: 1579979:WM2015_RS08450
uniprot id: A0A0K0XWM9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1579979:WM2015 RS14550
gene id: 1579979:WM2015_RS14550
uniprot id: A0A0K0XZZ8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1579979:WM2015 RS13245
gene id: 1579979:WM2015_RS13245
uniprot id: A0A0K0XZ76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1579979:WM2015 RS07410
gene id: 1579979:WM2015_RS07410
uniprot id: A0A0K0XW29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1579979:WM2015 RS08830
gene id: 1579979:WM2015_RS08830
uniprot id: A0A0K0XWQ1
names: Similarity
messages: Belongs to the IMPACT family.

1579979:WM2015 RS05170
gene id: 1579979:WM2015_RS05170
uniprot id: A0A0K0XUW0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1579979:WM2015 RS10505
gene id: 1579979:WM2015_RS10505
uniprot id: A0A0K0XXV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1579979:WM2015 RS10550
gene id: 1579979:WM2015_RS10550
uniprot id: A0A0K0XXP6
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1579979:WM2015 RS13290
gene id: 1579979:WM2015_RS13290
uniprot id: A0A0K0XZ87
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1579979:WM2015 RS01785
gene id: 1579979:WM2015_RS01785
uniprot id: A0A0K0XSQ9
names: Similarity
messages: Belongs to the CutA family.

1579979:WM2015 RS10485
gene id: 1579979:WM2015_RS10485
uniprot id: A0A0K0XXS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1579979:WM2015 RS03015
gene id: 1579979:WM2015_RS03015
uniprot id: A0A0K0XTN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1579979:WM2015 RS01570
gene id: 1579979:WM2015_RS01570
uniprot id: A0A0K0XSQ1
names: Similarity
messages: Belongs to the Smg family.

1579979:WM2015 RS02620
gene id: 1579979:WM2015_RS02620
uniprot id: A0A0K0XT64
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS00975
gene id: 1579979:WM2015_RS00975
uniprot id: A0A0K0XSH8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1579979:WM2015 RS10930
gene id: 1579979:WM2015_RS10930
uniprot id: A0A0K0XXX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1579979:WM2015 RS00470
gene id: 1579979:WM2015_RS00470
uniprot id: A0A0K0XS87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1579979:WM2015 RS02370
gene id: 1579979:WM2015_RS02370
uniprot id: A0A0K0XT69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1579979:WM2015 RS09405
gene id: 1579979:WM2015_RS09405
uniprot id: A0A0K0XX84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1579979:WM2015 RS14135
gene id: 1579979:WM2015_RS14135
uniprot id: A0A0K0XZT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1579979:WM2015 RS13050
gene id: 1579979:WM2015_RS13050
uniprot id: A0A0K0XZ89
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS00625
gene id: 1579979:WM2015_RS00625
uniprot id: A0A0K0XSB9
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS02805
gene id: 1579979:WM2015_RS02805
uniprot id: A0A0K0XTJ2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1579979:WM2015 RS14870
gene id: 1579979:WM2015_RS14870
uniprot id: A0A0K0Y034
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1579979:WM2015 RS05055
gene id: 1579979:WM2015_RS05055
uniprot id: A0A0K0XUM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1579979:WM2015 RS05270
gene id: 1579979:WM2015_RS05270
uniprot id: A0A0K0XUX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1579979:WM2015 RS12135
gene id: 1579979:WM2015_RS12135
uniprot id: A0A0K0XYJ2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1579979:WM2015 RS14435
gene id: 1579979:WM2015_RS14435
uniprot id: A0A0K0Y001
names: Similarity
messages: Belongs to the HsdR family.

1579979:WM2015 RS07295
gene id: 1579979:WM2015_RS07295
uniprot id: A0A0K0XW09
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1579979:WM2015 RS09975
gene id: 1579979:WM2015_RS09975
uniprot id: A0A0K0XXJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1579979:WM2015 RS09615
gene id: 1579979:WM2015_RS09615
uniprot id: A0A0K0XXA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1579979:WM2015 RS02195
gene id: 1579979:WM2015_RS02195
uniprot id: A0A0K0XT35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1579979:WM2015 RS01160
gene id: 1579979:WM2015_RS01160
uniprot id: A0A0K0XSF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1579979:WM2015 RS08550
gene id: 1579979:WM2015_RS08550
uniprot id: A0A0K0XWK7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1579979:WM2015 RS10710
gene id: 1579979:WM2015_RS10710
uniprot id: A0A0K0XXX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1579979:WM2015 RS10205
gene id: 1579979:WM2015_RS10205
uniprot id: A0A0K0XXM1
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1579979:WM2015 RS00710
gene id: 1579979:WM2015_RS00710
uniprot id: A0A0K0XS71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1579979:WM2015 RS03025
gene id: 1579979:WM2015_RS03025
uniprot id: A0A0K0XTE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1579979:WM2015 RS10160
gene id: 1579979:WM2015_RS10160
uniprot id: A0A0K0XXG2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1579979:WM2015 RS07795
gene id: 1579979:WM2015_RS07795
uniprot id: A0A0K0XW51
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1579979:WM2015 RS06910
gene id: 1579979:WM2015_RS06910
uniprot id: A0A0K0XVU9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1579979:WM2015 RS02670
gene id: 1579979:WM2015_RS02670
uniprot id: A0A0K0XT72
names: Similarity
messages: Belongs to the peptidase S16 family.

1579979:WM2015 RS00020
gene id: 1579979:WM2015_RS00020
uniprot id: A0A0K0XRW6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1579979:WM2015 RS07960
gene id: 1579979:WM2015_RS07960
uniprot id: A0A0K0XWE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1579979:WM2015 RS08255
gene id: 1579979:WM2015_RS08255
uniprot id: A0A0K0XWF2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1579979:WM2015 RS00120
gene id: 1579979:WM2015_RS00120
uniprot id: A0A0K0XRY5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1579979:WM2015 RS04435
gene id: 1579979:WM2015_RS04435
uniprot id: A0A0K0XUC4
names: Subcellular Location Annotation
messages: Membrane

1579979:WM2015 RS11600
gene id: 1579979:WM2015_RS11600
uniprot id: A0A0K0XYA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1579979:WM2015 RS09765
gene id: 1579979:WM2015_RS09765
uniprot id: A0A0K0XX81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1579979:WM2015 RS00800
gene id: 1579979:WM2015_RS00800
uniprot id: A0A0K0XSE9
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1579979:WM2015 RS07470
gene id: 1579979:WM2015_RS07470
uniprot id: A0A0K0XVW0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1579979:WM2015 RS13070
gene id: 1579979:WM2015_RS13070
uniprot id: A0A0K0XZ41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1579979:WM2015 RS15060
gene id: 1579979:WM2015_RS15060
uniprot id: A0A0K0Y0C7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1579979:WM2015 RS06880
gene id: 1579979:WM2015_RS06880
uniprot id: A0A0K0XVT9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1579979:WM2015 RS09610
gene id: 1579979:WM2015_RS09610
uniprot id: A0A0K0XXC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

1579979:WM2015 RS02410
gene id: 1579979:WM2015_RS02410
uniprot id: A0A0K0XTB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1579979:WM2015 RS09490
gene id: 1579979:WM2015_RS09490
uniprot id: A0A0K0XX32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1579979:WM2015 RS01150
gene id: 1579979:WM2015_RS01150
uniprot id: A0A0K0XSL4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1579979:WM2015 RS03900
gene id: 1579979:WM2015_RS03900
uniprot id: A0A0K0XU46
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1579979:WM2015 RS12415
gene id: 1579979:WM2015_RS12415
uniprot id: A0A0K0XYR6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1579979:WM2015 RS07925
gene id: 1579979:WM2015_RS07925
uniprot id: A0A0K0XW53
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1579979:WM2015 RS04815
gene id: 1579979:WM2015_RS04815
uniprot id: A0A0K0XUP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1579979:WM2015 RS12500
gene id: 1579979:WM2015_RS12500
uniprot id: A0A0K0XYY0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1579979:WM2015 RS10880
gene id: 1579979:WM2015_RS10880
uniprot id: A0A0K0XXW2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1579979:WM2015 RS11730
gene id: 1579979:WM2015_RS11730
uniprot id: A0A0K0XYG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1579979:WM2015 RS08645
gene id: 1579979:WM2015_RS08645
uniprot id: A0A0K0XWJ5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1579979:WM2015 RS04260
gene id: 1579979:WM2015_RS04260
uniprot id: A0A0K0XU93
names: Similarity
messages: Belongs to the histone deacetylase family.

1579979:WM2015 RS07040
gene id: 1579979:WM2015_RS07040
uniprot id: A0A0K0XVR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1579979:WM2015 RS00240
gene id: 1579979:WM2015_RS00240
uniprot id: A0A0K0XRU8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1579979:WM2015 RS02790
gene id: 1579979:WM2015_RS02790
uniprot id: A0A0K0XTC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1579979:WM2015 RS04520
gene id: 1579979:WM2015_RS04520
uniprot id: A0A0K0XUI3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1579979:WM2015 RS02440
gene id: 1579979:WM2015_RS02440
uniprot id: A0A0K0XT52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS09200
gene id: 1579979:WM2015_RS09200
uniprot id: A0A0K0XWX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS03840
gene id: 1579979:WM2015_RS03840
uniprot id: A0A0K0XTV5
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1579979:WM2015 RS11145
gene id: 1579979:WM2015_RS11145
uniprot id: A0A0K0XXY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1579979:WM2015 RS08405
gene id: 1579979:WM2015_RS08405
uniprot id: A0A0K0XWE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1579979:WM2015 RS07510
gene id: 1579979:WM2015_RS07510
uniprot id: A0A0K0XW59
names: Similarity
messages: Belongs to the oxoprolinase family.

1579979:WM2015 RS09085
gene id: 1579979:WM2015_RS09085
uniprot id: A0A0K0XWZ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1579979:WM2015 RS10010
gene id: 1579979:WM2015_RS10010
uniprot id: A0A0K0XXD3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1579979:WM2015 RS10905
gene id: 1579979:WM2015_RS10905
uniprot id: A0A0K0XXW7
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1579979:WM2015 RS06770
gene id: 1579979:WM2015_RS06770
uniprot id: A0A0K0XVM6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1579979:WM2015 RS09455
gene id: 1579979:WM2015_RS09455
uniprot id: A0A0K0XX94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1579979:WM2015 RS12610
gene id: 1579979:WM2015_RS12610
uniprot id: A0A0K0XZ02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1579979:WM2015 RS11375
gene id: 1579979:WM2015_RS11375
uniprot id: A0A0K0XY64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1579979:WM2015 RS11935
gene id: 1579979:WM2015_RS11935
uniprot id: A0A0K0XYF8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1579979:WM2015 RS02795
gene id: 1579979:WM2015_RS02795
uniprot id: A0A0K0XTA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane